Zhonghua Bing Li Xue Za Zhi 2021 Nov;50(11):1240-1245
Department of Pathology, Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory of Head and Neck Molecular Diagnostic Pathology, Beijing 100730, China.
To investigate the clinicopathological characteristics, diagnosis, differential diagnosis and prognostic factors of SMARCB1 (INI1)-deficient sinonasal carcinoma (SDSC). Sixteen cases of SDSC diagnosed in the Department of Pathology, Beijing Tongren Hospital from January 2016 to September 2020 were enrolled. Ninety-nine cases of small round cell malignant tumors of the head and neck were selected as the control, including poorly-differentiated squamous cell carcinoma (10), poorly-differentiated adenocarcinoma (5), undifferentiated carcinoma (SNUC, 4), NUT carcinoma (5), neuroendocrine carcinoma (10), and other non-epithelial tumors [olfactory neuroblastoma (10), rhabdomyosarcoma (10), NK/T-cell lymphoma (10), malignant melanoma (10), Ewing's sarcoma/primitive neuroectodermal tumor (EWS/PNET, 5)] and non-keratinizing undifferentiated nasopharyngeal carcinoma (20). Read More