4,251 results match your criteria Lymphomas of the Head and Neck


19th International Symposium on Epstein-Barr Virus and Associated Diseases, 29-30 July 2021, Asahikawa, Japan.

Cancers (Basel) 2022 Jun 14;14(12). Epub 2022 Jun 14.

Department of Otolaryngology-Head and Neck Surgery, Asahikawa Medical University, Asahikawa 078-8510, Japan.

Novel insights into Epstein-Barr virus (EBV) pathogenicity were presented at the "19th International Symposium on Epstein-Barr Virus and Associated Diseases" in Asahikawa, Japan. In addition, basic and translational findings on EBV-associated tumors, including natural killer (NK)/T-cell lymphoma, gastric cancer, and nasopharyngeal cancer, were presented by an international group of scientists and clinicians. Read More

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Decision criteria for resource allocation: an analysis of CONITEC oncology reports.

Cien Saude Colet 2022 Jul 5;27(7):2563-2572. Epub 2021 Dec 5.

Departamento de Medicina Preventiva, Faculdade de Medicina da Universidade de São Paulo. São Paulo SP Brasil.

In health technology assessment (HTA), decision criteria are considered relevant to support the complex deliberative process that requires simultaneous consideration of multiple factors. The aim was to identify and analyze the decision criteria that have been used by the National Health Technology Assessment Commission (CONITEC) when recommending the incorporation of technologies for the treatment of cancer. Descriptive study, based on reports from CONITEC, between 2012 and 2018, on oncology technologies. Read More

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Histopathology of Head and Neck Lymphomas in Ibadan.

J West Afr Coll Surg 2020 Jul-Sep;10(3):40-44. Epub 2022 May 4.

Department of Oral and Maxillofacial Surgery, College of Medicine, University of Ibadan and University College Hospital, Ibadan, Oyo state, Nigeria.

Background: Lymphomas are a heterogeneous group of tumors of lymphoid tissue in which there is a malignant proliferation of cells of the lymphatic system. They are the most frequent nonepithelial malignancy in the head and neck region.

Objectives: The aim of this study was to evaluate the histological pattern of the disease in the head and neck region and trends in presentation seen in our center. Read More

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[Shock wave therapy in oncology: in vitro, in vivo, rehabilitation].

Vopr Kurortol Fizioter Lech Fiz Kult 2022 ;99(3):58-65

Moscow Scientific and Practical Center for Medical Rehabilitation, Restorative and Sports Medicine of the Department of Health of the City of Moscow, Moscow, Russia.

Extracorporeal shock wave therapy (ESWT) is a relatively new branch of physiotherapy.

Purpose Of The Study: Conduct an analytical review of the available literature data on the use of ESWT in oncology.

Material And Methods: A review was conducted, including data from electronic databases: Scopus, Web of Science, MedLine, World Health Organization, The Cochrane Central Register of Controlled Trials, ScienceDirect, US National Library of Medicine National Institutes of Health, PubMed, Google Scholar, elibrary, CyberLeninka, disserCat. Read More

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NK- and T-cell lymphoma of the nasal cavity and paranasal sinuses in Denmark 1980-2017: a nationwide cohort study.

Leuk Lymphoma 2022 Jun 14:1-10. Epub 2022 Jun 14.

Eye Pathology Section, Department of Pathology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

Compared to Asian and Latin American populations, sinonasal NK- or T-cell lymphoma is rare in Europe. All patients with sinonasal NK- or T-cell lymphoma in Denmark from 1980 to 2017 were validated histologically, and the disease behavior and demographics were extracted from medical records and national registries. Prognostic factors associated with mortality were determined using survival statistics. Read More

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The Rationale for "Laser-Induced Thermal Therapy (LITT) and Intratumoral Cisplatin" Approach for Cancer Treatment.

Int J Mol Sci 2022 May 25;23(11). Epub 2022 May 25.

Department of Otolaryngology and Head and Neck Surgery, Federal University of São Paulo (UNIFESP), Sao Paulo 04023-062, SP, Brazil.

Cisplatin is one of the most widely used anticancer drugs in the treatment of various types of solid human cancers, as well as germ cell tumors, sarcomas, and lymphomas. Strong evidence from research has demonstrated higher efficacy of a combination of cisplatin and derivatives, together with hyperthermia and light, in overcoming drug resistance and improving tumoricidal efficacy. It is well known that the antioncogenic potential of CDDP is markedly enhanced by hyperthermia compared to drug treatment alone. Read More

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PET-CT in Clinical Adult Oncology-V. Head and Neck and Neuro Oncology.

Cancers (Basel) 2022 May 31;14(11). Epub 2022 May 31.

Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT 84132, USA.

PET-CT is an advanced imaging modality with many oncologic applications, including staging, assessment of response to therapy, restaging, and longitudinal surveillance for recurrence. The goal of this series of six review articles is to provide practical information to providers and imaging professionals regarding the best use of PET-CT for specific oncologic indications, and the potential pitfalls and nuances that characterize these applications. In addition, key tumor-specific clinical information and representative PET-CT images are provided to outline the role that PET-CT plays in the management of oncology patients. Read More

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Multimodal Sonographic Appearance and Survival Outcomes of 69 Cases of Primary Thyroid Lymphoma Over 10 Years.

J Ultrasound Med 2022 Jun 8. Epub 2022 Jun 8.

Department of Ultrasound Medicine, Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer (IBMC), Chinese Academy Of Sciences, Hangzhou, China.

Objectives: To investigate ultrasound appearance and the survival outcomes for patients with primary thyroid lymphoma (PTL).

Methods: Ultrasonic images and clinical characteristics from pathologically confirmed 69 PTL patients (2008-2019) were retrospectively analyzed. The clinical characteristics, ultrasonic characters, and prognostic factors were analyzed. Read More

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Primary Burkitt lymphoma of the thyroid associated with Hashimoto's thyroiditis.

BMJ Case Rep 2022 Jun 7;15(6). Epub 2022 Jun 7.

Department of Otolaryngology, Head and Neck Surgery, Cantonal Hospital Graubunden, Chur, Switzerland.

Primary Burkitt lymphoma of the thyroid is an extremely rare entity with only a few reported cases. A female patient in her 70s with Hashimoto's thyroiditis presented with a 2-month history of progressive left-sided neck swelling. Ultrasound examination revealed a multinodular goitre and fine needle aspiration (FNA) showed no signs of malignancy. Read More

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Distinct Roles of Adenosine Deaminase Isoenzymes ADA1 and ADA2: A Pan-Cancer Analysis.

Front Immunol 2022 18;13:903461. Epub 2022 May 18.

Department of Clinical Laboratory, Tangdu Hospital, Air Force Medical University, Xi'an, China.

Objective: Adenosine deaminase (ADA) plays an important role in immune response, which includes two isoenzymes: ADA1 and ADA2. This study aims to explore the roles of ADA1 and ADA2 in cancers.

Methods: Human Protein Atlas (HPA) and Gene Expression Profiling Interactive Analysis (GEPIA2) databases were used to analyze the mRNA expression of ADA1 and ADA2 in human normal cells and tumor tissues. Read More

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Master of mimicry: Rare primary cutaneous anaplastic large cell lymphoma presenting as fungating parotid tumor-case report and review.

Int J Surg Case Rep 2022 May 30;94:107135. Epub 2022 Apr 30.

Reconstructive Sciences Unit, Hospital Universiti Sains Malayisa, Jalan Raja Perempuan Zainab II, Kubang Kerian, 16150 Kota Bharu, Kelantan, Malaysia. Electronic address:

Introduction: Primary cutaneous anaplastic large cell lymphomas (PC-ALCL) are rare. They fall within non-Hodgkin's lymphomas spectrum. Commonly misdiagnosed, this malignancy involving the skin has favorable prognosis. Read More

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Primary Diffuse Large B-Cell Lymphoma of the Frontal Sinus.

Ophthalmic Plast Reconstr Surg 2022 Jun 3. Epub 2022 Jun 3.

Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, Minnesota.

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Advanced Nasopharyngeal Carcinoma with Generalized Lymphadenopathy Masquerade as Lymphoma.

Iran J Otorhinolaryngol 2022 May;34(122):205-211

Department of Otorhinolaryngology-Head & Neck Surgery, School of Medical Sciences, University Sains Malaysia Health Campus, 16150 Kota Bharu, Kelantan, Malaysia.

Introduction: Nasopharyngeal carcinoma (NPC) is a nasopharyngeal epithelial neoplasm that has distinct aetiological, epidemiological and biological characteristics compared to other head and neck malignancies. Patients usually present late due to non-specific symptoms and deep location of the tumour in the nasopharynx.

Case Report: We would like to highlight a case of advanced NPC presenting with generalised lymphadenopathy, without the presence of an obvious nasopharyngeal mass that masqueraded as lymphoma in the initial stage. Read More

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[Clinical features and prognosis of children with Burkitt's lymphoma: an analysis of 62 cases].

Zhongguo Dang Dai Er Ke Za Zhi 2022 May;24(5):561-565

Department of Children's Hematology and Oncology, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.

Objectives: To study the clinical features and chemotherapy response of Burkitt's lymphoma (BL) in children and the influence of rituximab on the prognosis of children with BL.

Methods: A retrospective analysis was performed for the medical data of 62 children with BL, including clinical features, therapeutic efficacy, and prognostic factors. The Cox regression model was used to identify the factors associated with poor prognosis in children with BL. Read More

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Multimodality imaging of extra-nodal lymphoma in the head and neck.

Clin Radiol 2022 May 28. Epub 2022 May 28.

Department of Diagnostic and Interventional Radiology, Princess Margaret Hospital, Hong Kong.

Malignant lymphomas represent approximately 5% of all malignant neoplasms of the head and neck. The head and neck region is the second most frequent anatomical site of extra-nodal lymphomas (after the gastrointestinal tract). Most are non-Hodgkin's lymphomas of B-cell lineage, and overall diffuse large B-cell lymphoma is the most common type. Read More

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Dental MRI of Oral Soft-Tissue Tumors-Optimized Use of Black Bone MRI Sequences and a 15-Channel Mandibular Coil.

J Imaging 2022 May 22;8(5). Epub 2022 May 22.

Clinic of Cranio-Maxillofacial and Oral Surgery, Center of Dental Medicine, University of Zurich, 8032 Zurich, Switzerland.

Soft-tissue lesions in the oral cavity, one of the most common sites for tumors and tumor-like lesions, can be challenging to diagnose and treat due to the wide spectrum from benign indolent to invasive malignant lesions. We report an abnormally large, rapidly growing hyperplastic lesion originating from the buccal mucosa in a 28-year-old male patient. Clinical examination revealed a well-circumscribed, smooth-surfaced, pinkish nodular lesion measuring 2. Read More

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[Diffuse large B cell lymphoma misdiagnosed as peritonsillar abscess: a case report].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2022 May;57(5):629-631

Department of Otorhinolaryngology Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Shandong Provincial Clinical Research Center for Otorhinolaryngologic Disease, Yantai 264000, China.

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A Carotid Body Tumour Mimicking Richter's Transformation of Chronic Lymphocytic Leukaemia.

Cureus 2022 Apr 18;14(4):e24262. Epub 2022 Apr 18.

Department of Radiology, Basildon and Thurrock University Hospital, Basildon, GBR.

Carotid body tumours (CBT), also called carotid paragangliomas, are highly vascular glomus tumours that originate from paraganglionic cells of the carotid body. They are frequently asymptomatic, insidious, and non-secretory in nature. They typically present as a large, non-tender, pulsatile neck mass. Read More

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Recurrence 14 Years After Initial Treatment of Extranodal NK/T Cell Lymphoma, Nasal Type.

Cureus 2022 Apr 16;14(4):e24177. Epub 2022 Apr 16.

Department of Head and Neck Surgery-Otolaryngology, Ogaki Municipal Hospital, Ogaki, JPN.

Extranodal NK/T cell lymphoma, nasal type (ENKL) primarily involves the nasal cavity. Although patients might visit an otorhinolaryngologist with nasal symptoms, such as nasal obstruction and epistaxis, it would be difficult to make a diagnosis correctly. We present a case of ENKL in which the patient had been in remission after initial treatment and relapsed 14 years after treatment. Read More

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Otalgia and Facial Nerve Palsy: Common Symptoms Revealing the Uncommon Pathology of Middle Ear Lymphoma.

Cureus 2022 May 15;14(5):e25023. Epub 2022 May 15.

Otolaryngology - Head and Neck Surgery, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, MYS.

Lymphoma of the middle ear and mastoid is uncommon and is rarely diagnosed early. The clinical presentation occurs due to consequences of extensive progressive disease. It can manifest as benign middle ear pathologies such as otitis media; other presentations include facial nerve palsy, hearing loss, and vestibular dysfunction. Read More

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Timosaponin AIII Suppresses RAP1 Signaling Pathway to Enhance the Inhibitory Effect of Paclitaxel on Nasopharyngeal Carcinoma.

Comput Math Methods Med 2022 9;2022:6756676. Epub 2022 May 9.

Department of Head and Neck Surgery, People's Hospital of Guang'an City, Guang'an 638001, China.

Although PTX has been identified as an effective drug for nasopharyngeal carcinoma (NPC) therapy, it has serious side effects in the human body. Previous studies have shown that timosaponin AIII (TSAIII) can inhibit the malignant progression of NPC cells. This study investigated the active mechanism of the combination of TSAIII and paclitaxel (PTX) on NPC. Read More

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Change in Patients' Perceived Cognition Following Chimeric Antigen Receptor T-Cell Therapy for Lymphoma.

Transplant Cell Ther 2022 May 14. Epub 2022 May 14.

Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, Florida. Electronic address:

Chimeric antigen receptor (CAR) T-cell therapy can lead to durable responses in patients with relapsed/refractory hematologic malignancies. Immune effector cell-associated neurotoxicity syndrome (ICANS) and cytokine release syndrome (CRS) are common and may place patients at risk for longer-term cognitive impairment. This study examined changes in cognition in the first year after CD19-directed CAR T-cell therapy for lymphoma, as well as CAR T-cell therapy-specific risk-factors (e. Read More

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[Diagnostics and treatment of secondary malignancies of the parotid gland-An overview].

HNO 2022 May 17. Epub 2022 May 17.

Medizinische Fakultät und Uniklinik Köln, Klinik und Poliklinik für Hals-Nasen-Ohrenheilkunde, Kopf- und Hals-Chirurgie, Universität zu Köln, Kerpener Str. 62, 50937, Köln, Deutschland.

Background: Secondary malignancies of the parotid gland frequently have a cutaneous origin and the incidence in central Europe is increasing.

Objective: The aim of this review article was to present the epidemiology, (differential) diagnostics and treatment of secondary malignancies of the parotid gland.

Material And Methods: A literature search of the current guidelines and evidence was carried out in the web-based databank PubMed. Read More

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Extramedullary plasmacytoma: Tumor occurrence and therapeutic concepts-A follow-up.

Cancer Med 2022 May 16. Epub 2022 May 16.

Department of Otorhinolaryngology, Head & Neck Surgery, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

Background: Extramedullary plasmacytoma (EMP) is a solitary tumor consisting of neoplastic plasma cells, with very little to no bone marrow involvement. EMPs are usually located in the head and neck region, but can also occur along the digestive tract, in lungs, or extremities.

Methods: Following our publication on EMP, which appeared in 1999 (Cancer 85:2305-14), we conducted a literature search for EMP-related reports published between 1999 and 2021. Read More

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Enlargement of Inferior Alveolar Nerve Canal and Mental Neuropathy Associated With B-Cell Lymphoma: A Case Report and Literature Review.

J Oral Maxillofac Surg 2022 Apr 15. Epub 2022 Apr 15.

Assistant Professor of Oral and Maxillofacial Surgery, Chief of Oral and Maxillofacial Surgery, Philadelphia Veterans Affairs Medical Center, University of Pennsylvania Presbyterian Medical Center, Philadelphia, PA.

Enlargement of an inferior alveolar nerve canal (IANC) on radiographic imaging can indicate the presence of a wide variety of pathologic entities. Oral and maxillofacial surgeons have the unique opportunity to regularly examine panoramic radiographs and must exercise proficient clinical judgment when noting abnormal findings on imaging. While malignant processes associated with IANC enlargement are uncommon, these pathologies do occur and may be associated with significant sequelae, especially when accompanied by a delay in diagnosis in treatment. Read More

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Clustering of EORTC QLQ-C30 health-related quality of life scales across several cancer types: Validation study.

Eur J Cancer 2022 Jul 13;170:1-9. Epub 2022 May 13.

European Organization for Research and Treatment of Cancer (EORTC), Brussels, Belgium.

Introduction: The European Organisation for Research and Treatment of Cancer Quality of Life Core Questionnaire (EORTC QLQ-C30) measures 15 health-related quality of life (HRQoL) scales relevant to the disease and treatment of patients with cancer. A study by Martinelli (2011) demonstrated that these scales could be grouped into three main clusters: physical, psychological and gastrointestinal. This study aims to validate Martinelli's findings in an independent dataset and evaluate whether these clusters are consistent across cancer types and patient characteristics. Read More

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Primary Cutaneous Anaplastic Large Cell Lymphoma of the Nasal Dorsum and Nasal Tip.

Cureus 2022 Apr 4;14(4):e23811. Epub 2022 Apr 4.

Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital of Ioannina, Ioannina, GRC.

Primary cutaneous anaplastic large-cell lymphoma (C-ALCL) is described as a non-Hodgkin lymphoma that affects only the skin, with no evidence of an extracutaneous disease during the first six months following the diagnosis. We present an unusual case of a 53-year-old man with developed fever and a rapidly increasing ulcerated skin lesion located on the nasal dorsum and nasal tip. The nasal endoscopy revealed a reddish polypoid lesion over the anterior edge of the superior turbinate which had extended through the roof of the nasal cavity in the adjacent area of the nasal septum. Read More

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Myeloid cell leukemia-1 expression in cancers of the oral cavity: a scoping review.

Cancer Cell Int 2022 May 6;22(1):182. Epub 2022 May 6.

Department of Oral Pathology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, 03080, Republic of Korea.

Background: B cell lymphoma-2 (Bcl-2) family members play important roles in cell survival as well as cell death. The role of myeloid cell leukemia-1 (Mcl-1), an important member of the Bcl-2 family, is well established in hematopoietic malignancies. However, the association between Mcl-1 and oral cavity, cancers is not clearly defined. Read More

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Prevalence of Epstein-Barr virus infection in individuals with nasopharyngeal carcinoma in Malaysia: The first systematic review and meta-analysi.

Trop Biomed 2022 Mar;39(1):89-98

Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.

Epstein-Barr virus (EBV) was the first herpesvirus associated to human malignancies. Despite the well-known association between EBV and malignancies, the prevalence of EBV infection in Malaysians with malignancies is unknown. Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) was used to conduct a systematic review and meta- analysis of published data in this study. Read More

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Prognostic values of myeloid differentiation factor 88 (MYD88) and transducin (β)-like receptor 1 (TBLR1) expression in tissues of diffuse large B-cell non-Hodgkin lymphoma patients - an immunohistochemical study.

Contemp Oncol (Pozn) 2022 30;26(1):49-58. Epub 2022 Mar 30.

Department of General Surgery, Faculty of Medicine, Benha, Egypt.

Introduction: Diffuse large B-cell non- Hodgkin lymphoma (DLBCL) is the largest common category of adult lymphoma. Recurrence and treatment resistance occurs in one-third of cases, triggering them to the progressive stage of DLBCL after treatment. Detection of novel predictive and prognostic biomarkers leads to improvement of its treatment and prognosis. Read More

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