5,870 results match your criteria Lymphoma Mediastinal


The role of mediastinoscopy in the diagnosis of thoracic disease: 107-case analysis.

Med Glas (Zenica) 2019 Aug 1;16(2). Epub 2019 Aug 1.

Department of Thoracic Surgery, School of Medicine, Canakkale Onsekiz Mart University, Turkey.

Aim To evaluate the efficacy, safety and feasibility of mediastinoscopy in 107 cases with mediastinal lesions that could not be diagnosed histopathologically with other methods. Methods A total of 107 cases (73 males, 34 females; mean age 57.4, range 30-88 years) with mediastinal lymphadenopathy, who underwent mediastinoscopy between 12 September 2012 and 29 November 2018 were examined retrospectively. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17392/1001-19DOI Listing

Clinical features and outcomes of diffuse large B-cell lymphoma based on nodal or extranodal primary sites of origin: Analysis of 1,085 WHO classified cases in a single institution in China.

Chin J Cancer Res 2019 Feb;31(1):152-161

Department of Medical Oncology, Beijing Key Laboratory of Clinical Study on Anticancer Molecular Targeted Drugs, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

Objective: To explore the clinicobiologic features and outcomes of diffuse large B-cell lymphoma (DLBCL) patients in China according to the primary site.

Methods: A total of 1,085 patients diagnosed with DLBCL in National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College during a 6-year period were enrolled. Their clinical characteristics and outcomes were analyzed according to the primary site. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21147/j.issn.1000-9604.2019.01.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433587PMC
February 2019

Image-guided Fine Needle Aspiration Cytology of Intrathoracic Lesions.

J Cytol 2019 Apr-Jun;36(2):106-110

Department of Pulmonary Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Mangalore, Karnataka, India.

Background: Percutaneous, image-guided transthoracic fine needle aspiration cytology (TTFNAC) is a rapid, yet accurate, and well-established diagnostic method used in the cytological evaluation of intrathoracic lesions. The study was done to determine the utility of image-guided TTFNAC in diagnosis of intrathoracic lesions.

Subjects And Methods: A retrospective analysis of all cases who underwent image-guided TTFNAC of a suspected intrathoracic lesion, in a tertiary care hospital was done over a period of 3 years. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/JOC.JOC_187_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425786PMC

Consolidative mediastinal irradiation of malignant lymphoma using active scanning proton beams: clinical outcome and dosimetric comparison.

Strahlenther Onkol 2019 Apr 10. Epub 2019 Apr 10.

Department of Radiation Oncology, University Hospital Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.

Purpose: Current research approaches in lymphoma focus on reduction of therapy-associated long-term side effects. Especially in mediastinal lymphoma, proton beam radiotherapy (PT) may be a promising approach for reducing the dose to organs at risk (OAR).

Patients: In total, 20 patients were irradiated with active scanning PT at Heidelberg Ion Beam Therapy Center (HIT) between September 2014 and February 2017. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00066-019-01460-7DOI Listing
April 2019
2 Reads

Primary Mediastinal Large B-Cell Lymphoma in a Child Presenting With Superior Mediastinal Syndrome and Chylous Pleural and Pericardial Effusion.

J Pediatr Hematol Oncol 2019 Apr 3. Epub 2019 Apr 3.

Departments of Pediatric Oncology.

Primary mediastinal (thymic) large B-cell lymphoma is an aggressive B-cell lymphoma. It comprises <3% of all pediatric non-Hodgkin lymphomas (NHLs). Primary mediastinal (thymic) large B-cell lymphoma usually presents with serous pleural effusion, but presentation with chylous pleural and pericardial effusions is rare. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MPH.0000000000001472DOI Listing
April 2019
4 Reads

Mediastinal peripheral T-cell lymphoma presenting with hematemesis.

Dig Liver Dis 2019 Mar 26. Epub 2019 Mar 26.

The University of Texas Medical Branch, Department of Gastroenterology and Hepatology, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.dld.2019.02.016DOI Listing
March 2019
1 Read

Clinical Predictors and Prognostic Model for Pediatric Lymphoblastic Lymphoma Treated With Uniform BFM90 Protocol: A Single-Center Experience of 65 Patients From Asia.

Clin Lymphoma Myeloma Leuk 2019 Feb 8. Epub 2019 Feb 8.

Department of Medical Oncology, Dr BRA IRCH, All India Institute of Medical Sciences, New Delhi, India. Electronic address:

Background: There is a lack of clinical predictors for prognosticating lymphoblastic lymphoma (LBL). In view of this lacuna, we evaluated outcomes and prognostic factors for LBL treated with a uniform protocol at our center.

Patients And Methods: This study included consecutive patients of pediatric LBL aged ≤18 years from January 2003 to January 2017. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clml.2019.01.008DOI Listing
February 2019
1 Read

Cytology versus histology in the primary diagnosis of lymphoma located in the mediastinum.

Ann Thorac Surg 2019 Mar 20. Epub 2019 Mar 20.

Department of Thoracic Surgery and Thoracic Endoscopy, Ruhrlandklinik, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany.

Background: Endobronchial ultrasound-guided transbronchial needle aspirations (EBUS-TBNA) are well-established for staging lung cancer. A growing number of publications report on lymphoma diagnosis via EBUS-TBNA acquired cytology; however, current guidelines recommend histological diagnosis. Research on the value of EBUS-TBNA acquired cytology versus surgical acquired histology in the diagnosis of lymphoma is lacking. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00034975193037
Publisher Site
http://dx.doi.org/10.1016/j.athoracsur.2019.02.030DOI Listing
March 2019
5 Reads

Utility and safety of endobronchial ultrasound-guided transbronchial needle aspiration and endoscopic ultrasound with an echobronchoscope-guided fine needle aspiration in children with mediastinal pathology.

Pediatr Pulmonol 2019 Mar 19. Epub 2019 Mar 19.

Division of Pediatric Pulmonology, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.

Background: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) and endoscopic ultrasound with an echobronchoscope-guided fine needle aspiration (EUS-B-FNA) are useful modalities in the evaluation of mediastinal pathologies in adults. However, sparse data are available in children.

Objective: To describe the utility and safety of EBUS-TBNA and EUS-B-FNA in children with mediastinal pathologies of unknown etiology. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ppul.24313DOI Listing
March 2019
1 Read

A possible case of Erdheim-Chester Disease.

Rom J Ophthalmol 2018 Oct-Dec;62(4):308-311

University Hospital in Château-Gontier, France.

To present the case of a 57-year-old male with progressive bilateral proptosis. The patient presented with bilateral proptosis and strength deficiency on the upper limbs. During hospitalization, the progression was unfavorable; proptosis progressed, causing a severe loss of vision in the left eye (from 0. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421492PMC

Persistent Anemia Combined Increased Serum Sedimentation (ESR) for More Than Two Years Firstly Misdiagnosed as Lymphoma Ultimately Confirmed Systemic Lymph Nodes Tuberculosis by Endobronchial Ultrasound-guided Transbronchial Needle Aspiration Pathology: a Case Report and Literature Review.

Clin Lab 2019 Mar;65(3)

Background: Anemia combined with increased serum sedimentation (ESR) can be secondary to many diseases and may be ignored when the patient had few clinical symptoms. We report a case of persistent anemia combined with ESR for more than 2 years firstly misdiagnosed as lymphoma. When she received a chest CT scan multiple enlarged lymph nodes were found. Read More

View Article

Download full-text PDF

Source
http://www.clin-lab-publications.com/article/2941
Publisher Site
http://dx.doi.org/10.7754/Clin.Lab.2018.180836DOI Listing
March 2019
4 Reads

Phase 2 Study of Dose-Reduced Consolidation Radiation Therapy in Diffuse Large B-Cell Lymphoma.

Int J Radiat Oncol Biol Phys 2019 Mar 8. Epub 2019 Mar 8.

Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina.

Purpose: To evaluate the feasibility of reducing the dose of consolidation radiation therapy (RT) in diffuse large B-cell lymphoma.

Methods And Materials: This phase 2 study enrolled patients with diffuse large B-cell lymphoma, not otherwise specified and primary mediastinal (thymic) large B-cell lymphoma in complete response on positron emission tomography-computed tomography imaging after ≥4 cycles of a rituximab/anthracycline-containing combination chemotherapy regimen. Consolidation RT used a dose of 19. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijrobp.2019.02.055DOI Listing
March 2019
4 Reads

[Successful treatment with preceding low-intensity chemotherapy in a primary mediastinal large B cell lymphoma patient diagnosed at 11 weeks of pregnancy].

Rinsho Ketsueki 2019;60(2):112-117

Department of Hematology, Kawaguchi Municipal Medical Center.

At 11 weeks of pregnancy, a 31-year-old woman presented with an anterior chest tumor and dyspnea. A computed tomography (CT) scan revealed a bulky tumor in the mediastinum that compressed the trachea. She underwent a CT-guided needle biopsy and was diagnosed with primary mediastinal large B cell lymphoma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.11406/rinketsu.60.112DOI Listing
January 2019
1 Read

[A Case of Upper Urinary Tract MALT Lymphoma with Remarkable Thickness of Renal Pelvis and Ureter Wall].

Hinyokika Kiyo 2018 Dec;64(12):489-495

The Department of Urology, Faculty of Medicine, University of Tsukuba.

A 78-year-old man was referred to Tsukuba University Hospital for right hydronephrosis. He had undergone ureteroscopy and ureteral stenting in another hospital, but no tumor was revealed in renal pelvis and ureter. The urinary cytology was negative. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14989/ActaUrolJap_64_12_489DOI Listing
December 2018
2 Reads

Pediatric Malignant Mediastinal Masses.

J Coll Physicians Surg Pak 2019 Mar;29(3):258-262

Department of Pediatric Hematology-Oncology and Bone Marrow Transplant, The Children's Hospital and Institute of Child Health, Lahore, Pakistan.

Objective: To describe the clinical spectrum and outcome-associated variables of pediatric malignant mediastinal masses in a resource-limited setting.

Study Design: Descriptive study.

Place And Duration Of Study: Department of Pediatric Hematology-Oncology, The Children's Hospital, Lahore, from October 2016 to November 2017. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.29271/jcpsp.2019.03.258DOI Listing
March 2019
4 Reads

Histological findings in patients with suspected mediastinal lymphoma relapse according to positive positron emission tomography scan during follow-up: a large retrospective analysis in 96 patients.

Leuk Lymphoma 2019 Mar 1:1-8. Epub 2019 Mar 1.

a Institute of Hematology "L. e A. Seràgnoli", University of Bologna , Bologna , Italy.

Residual masses in patients with mediastinal lymphoma may be positron emission tomography (PET) positive during follow-up also in cases of complete response. The aim of this retrospective study is to verify the reliability of mediastinal PET-positive findings in suggesting disease relapse or progression during follow-up by histological verification. From January 2002 to March 2016, 96 patients with mediastinal lymphoma underwent PET follow-up after front-line treatment. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/10428194.2019.1
Publisher Site
http://dx.doi.org/10.1080/10428194.2019.1581931DOI Listing
March 2019
9 Reads

Lymphoblastic lymphoma in children and adolescents: review of current challenges and future opportunities.

Br J Haematol 2019 Feb 27. Epub 2019 Feb 27.

Pediatric Hematology and Oncology, University of California, San Francisco, CA, USA.

Lymphoblastic lymphoma (LBL) is the second most common type of Non-Hodgkin Lymphoma (NHL) in childhood and adolescence, accounting for 25-35% of all cases. The majority, 70-80%, is of T-lymphoblastic origin while 20-25% arise from B lymphoblasts. With current therapy, the event-free and overall survivals for paediatric LBL patients now exceeds 80%. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bjh.15793DOI Listing
February 2019
1 Read

Life-Saving Stenting of Pulmonary Arteries Critically Narrowed by Mediastinal Lymphoma.

Am J Respir Crit Care Med 2019 Feb 26. Epub 2019 Feb 26.

Silesian Centre for Heart Diseases, Department of Cardiac Anesthesia and Intensive Care, Zabrze, Poland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/rccm.201807-1366IMDOI Listing
February 2019
3 Reads

Baseline PET features to predict prognosis in primary mediastinal B cell lymphoma: a comparative analysis of different methods for measuring baseline metabolic tumour volume.

Eur J Nucl Med Mol Imaging 2019 Feb 26. Epub 2019 Feb 26.

Institute of Oncology Research, Bellinzona, Switzerland.

Purpose: This study assessed the performance of four different methods for the estimation of metabolic tumour volume (MTV) in primary mediastinal B cell lymphoma (PMBCL).

Method: MTV was estimated using either a region growing automatic software program (RG) or a fixed threshold (FT) segmentation algorithm with the three most common cut-offs proposed in the literature (i.e. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00259-019-04286-8DOI Listing
February 2019
1 Read

Excellent Outcomes of Grey Zone Lymphoma: Case Series of Paediatric Patients Treated at a Single Centre.

J Pak Med Assoc 2019 Feb;69(2):267-270

Shaukat Khanum Memorial Cancer Hospital & Research Centre, Lahore, Pakistan.

Our objective was to review clinical presentation, treatment protocol used and its efficacy and effectiveness in patients of grey zone lymphoma during last 5 years at our centre. A retrospective chart review of children below 18 years of age was done from 2011 to 2016. A proforma was devised for this purpose and the findings of cases detected during the specified period were noted over it. Read More

View Article

Download full-text PDF

Source
February 2019
1 Read

American Registry of Pathology Expert Opinions: Immunohistochemical evaluation of classic Hodgkin lymphoma.

Ann Diagn Pathol 2019 Feb 6;39:105-110. Epub 2019 Feb 6.

Mayo Clinic, Rochester, MN, United States of America.

The diagnosis of classic Hodgkin lymphoma requires immunohistochemical confirmation in most cases and one can argue for these studies as standard-of-care in the diagnostic workup. The authors propose a panel of studies for primary identification of CHL to include: CD3, CD20, CD15, CD30 and PAX5. When pattern discordances are identified, additional assessment is recommended. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.anndiagpath.2019.02.001DOI Listing
February 2019
1 Read

Sensitivity and specificity of fine needle aspiration for the diagnosis of mediastinal lesions.

Ann Diagn Pathol 2019 Feb 10;39:69-73. Epub 2019 Feb 10.

Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA. Electronic address:

Fine needle aspiration cytology (FNAC) of mediastinal masses allows for rapid on-site evaluation and the triaging of material for ancillary studies. However, surgical pathology is often considered to be the gold standard for diagnosis. This study examines the sensitivity and specificity of FNAC compared to a concurrent or subsequent surgical pathology specimen in 77 mediastinal lesions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.anndiagpath.2019.02.011DOI Listing
February 2019
2 Reads

Durable response to the ALK inhibitor alectinib in inflammatory myofibroblastic tumor of the head and neck with a novel SQSTM1-ALK fusion: a case report.

Invest New Drugs 2019 Feb 21. Epub 2019 Feb 21.

Department of Clinical Oncology, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi, 464-8681, Japan.

An inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal neoplasm that typically develops in the lungs and seldom in the head and neck region. It is often related to the anaplastic lymphoma kinase (ALK) fusion gene. Crizotinib, a first-generation ALK inhibitor, has been shown to have a notable response in patients with ALK-positive IMT. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10637-019-00742-2DOI Listing
February 2019
5 Reads

Ibrutinib Caused Mediastinal Emphysema and Pneumothorax in the Treatment of a Patient with Mantle Cell Lymphoma.

Drug Saf Case Rep 2019 Feb 21;6(1). Epub 2019 Feb 21.

Department of Hematology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

A 70-year-old Japanese man with mantle cell lymphoma underwent extensive chemotherapy and radiation because of the relapse of mantle cell lymphoma. He developed mediastinal emphysema and a pneumothorax 14 days after treatment with 560 mg of ibrutinib. The mediastinal emphysema and the right pneumothorax disappeared after the ibrutinib treatment was tapered off. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s40800-019-0098-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384285PMC
February 2019
1 Read

Can we differentiate malignant peripheral nerve sheath tumor from benign neurofibroma without invasive sampling.

World J Nucl Med 2019 Jan-Mar;18(1):66-68

Department of Nuclear Medicine, Elazig Medical Park Hospital, Elazığ, Turkey.

One of the most important benign tumors in neurofibromatosis type 1 (NF1) is plexiform neurofibroma, and there is a risk of developing malignant peripheral nerve sheath tumor (MPNST) throughout life approximately 10%. However lesion characterization by anatomical imaging methods are not possible. Because of that most of cases goes to biopsy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/wjnm.WJNM_11_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357707PMC
February 2019
2 Reads

Imaging features of SMARCA4-deficient thoracic sarcomas: a multi-centric study of 21 patients.

Eur Radiol 2019 Feb 14. Epub 2019 Feb 14.

Department of Radiology, Institut Bergonié, Comprehensive Cancer Center, 229, cours de l'Argonne, F-33000, Bordeaux, France.

Objectives: SMARCA4-deficient thoracic sarcoma (SMARCA4-DTS) is a recently identified aggressive subtype of sarcoma. The aim of this study was to characterize the CT imaging features of SMARCA4-DTS.

Methods: From June 2011 to May 2017, 21 adult patients with histologically proven SMARCA4-DTS were identified in the radiological database of 2 French sarcoma reference centers with at least one chest CT scan available. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00330-019-06017-xDOI Listing
February 2019
5 Reads

Biology and therapy of primary mediastinal B-cell lymphoma: current status and future directions.

Br J Haematol 2019 Apr 10;185(1):25-41. Epub 2019 Feb 10.

Blood Cancer Research Group, Mater Research, University of Queensland, Translational Research Institute, Brisbane, QLD, Australia.

Primary mediastinal B-cell lymphoma (PMBCL) is a distinct disease closely related to classical nodular sclerosing Hodgkin lymphoma. Conventional diagnostic paradigms utilising clinical, morphological and immunophenotypical features can be challenging due to overlapping features with other B-cell lymphomas. Reliable diagnostic and prognostic biomarkers that are applicable to the conventional diagnostic laboratory are largely lacking. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bjh.15778DOI Listing
April 2019
1 Read

The optimal chemotherapy regimen for primary mediastinal B-cell lymphoma: we may never know.

Authors:
Peter Martin

Leuk Lymphoma 2019 May 8;60(5):1110-1111. Epub 2019 Feb 8.

a Department of Medicine , Weil Cornell Medicine , New York , NY , USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/10428194.2018.1535119DOI Listing
May 2019
2 Reads

[Ring-shaped lesions on a lung scan].

Ned Tijdschr Geneeskd 2019 Jan 30;163. Epub 2019 Jan 30.

Radboudumc, afd. Hematologie, Nijmegen.

A 25-year-old man was treated with pembrolizumab for a relapsed-refractory primary mediastinal large B-cell lymphoma. On an evaluation PET-CT scan multiple 'reversed halo signs' were noticed. No infectious cause was established and we diagnosed the lesions as pembrolizumab-induced pneumonitis, an immune-related adverse event. Read More

View Article

Download full-text PDF

Source
January 2019
3 Reads

A PET Radiomics Model to Predict Refractory Mediastinal Hodgkin Lymphoma.

Sci Rep 2019 Feb 4;9(1):1322. Epub 2019 Feb 4.

Department of Radiation Oncology, Division of Radiation Oncology, MD Anderson Cancer Center, Houston, TX, USA.

First-order radiomic features, such as metabolic tumor volume (MTV) and total lesion glycolysis (TLG), are associated with disease progression in early-stage classical Hodgkin lymphoma (HL). We hypothesized that a model incorporating first- and second-order radiomic features would more accurately predict outcome than MTV or TLG alone. We assessed whether radiomic features extracted from baseline PET scans predicted relapsed or refractory disease status in a cohort of 251 patients with stage I-II HL who were managed at a tertiary cancer center. Read More

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41598-018-37197-z
Publisher Site
http://dx.doi.org/10.1038/s41598-018-37197-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361903PMC
February 2019
11 Reads
5.078 Impact Factor

Primary central nervous system Hodgkin Lymphoma: A case discussion and a hypothesis on the etiology.

Avicenna J Med 2019 Jan-Mar;9(1):28-31

Hematogenix Laboratory Services, Tinley Park, IL, USA.

Hodgkin Lymphoma (HL) is a systemic disease with involvement of the cervical, supraclavicular, and mediastinal lymph nodes. It is commonly diagnosed in patients within the second and third decades of their lives. Diagnosis is usually made based on the distinct morphological and immunohistochemical characteristics, with the tissue biopsy being the cornerstone of workup. Read More

View Article

Download full-text PDF

Source
http://www.avicennajmed.com/preprintarticle.asp?id=240257
Publisher Site
http://dx.doi.org/10.4103/ajm.AJM_104_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335883PMC
January 2019
12 Reads

Feline Lymphoma and a High Correlation with Feline Leukaemia Virus Infection in Brazil.

J Comp Pathol 2019 Jan 29;166:20-28. Epub 2018 Nov 29.

Laboratory of Animal Pathology, Agroveterinary Sciences Center, Brazil. Electronic address:

Lymphoma is the most important haemopoietic tumour in cats and has been associated with feline leukaemia virus (FeLV) infection. In Brazil, no studies have established a correlation between FeLV infection and lymphoma. The aim of this study was to characterize lymphomas arising in cats in Brazil anatomically and microscopically, and to correlate these data with FeLV infection as determined by immunohistochemistry for the FeLV gp70 antigen. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jcpa.2018.10.171DOI Listing
January 2019
1 Read

Cutaneous involvement as the first manifestation of T-lymphoblastic lymphoma and review of the literature.

J Cutan Pathol 2019 Jan 24. Epub 2019 Jan 24.

Department of Pathology, Hospital Universitario de La Princesa, Madrid, Spain.

Lymphoblastic lymphomas (LBLs) are uncommon malignant neoplasms derived from immature T- or B-lymphoid progenitor cells. Although cutaneous involvement may reach 33% in B-LBL, only 12 cutaneous cases of T-LBL have been published. We report the case of a 49-year-old woman with 2-month history of erythematous-violaceous plaques in the sternal region and breasts. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cup.13431DOI Listing
January 2019
1 Read

Spontaneous Regression of Clinically Indolent Lymphomas Revealed by 18F-FDG PET/CT.

Clin Nucl Med 2019 Apr;44(4):321-323

Department of Hematology, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing, China.

A 48-year-old man and a 55-year-old woman, who were diagnosed with follicular lymphoma and small B lymphocytic cell lymphoma, respectively, underwent initial "watch-and-wait" approach against lymphoma. The initial F-FDG PET/CT of both patients showed multiple FDG-avid lymph nodes in the neck, mediastinum, abdomen, and inguinal regions. During their active surveillance, the follow-up PET/CT of both patients revealed spontaneous regression of lymphoma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/RLU.0000000000002457DOI Listing
April 2019
5 Reads

Parapharyngeal Ganglioneuroma Detected by 18F-FDG PET/CT in a Patient With Hodgkin Lymphoma.

Clin Nucl Med 2019 Mar;44(3):240-243

Pathology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan.

A 38-year-old woman with anterior mediastinal Hodgkin lymphoma underwent F-FDG PET/CT, revealing abnormal uptake at the left retrostyloid parapharyngeal space. After chemotherapy, follow-up PET/CT showed regression of previously avid lesions but not the left retropharyngeal mass. Subsequent MRI revealed findings suggestive of neurogenic tumor. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/RLU.0000000000002444DOI Listing
March 2019
6 Reads

PET-adapted treatment for newly diagnosed advanced Hodgkin lymphoma (AHL2011): a randomised, multicentre, non-inferiority, phase 3 study.

Lancet Oncol 2019 Feb 15;20(2):202-215. Epub 2019 Jan 15.

LYSA Imaging, Hôpital H Mondor, Creteil, France.

Background: Increased-dose bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone (BEACOPP) improves progression-free survival in patients with advanced Hodgkin lymphoma compared with doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD), but is associated with increased risks of haematological toxicity, secondary myelodysplasia or leukaemia, and infertility. We investigated whether PET monitoring during treatment could allow dose de-escalation by switching regimen (BEACOPP to ABVD) in early responders without loss of disease control compared with standard treatment without PET monitoring.

Methods: AHL2011 is a randomised, non-inferiority, phase 3 study done in 90 centres across Belgium and France. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1470-2045(18)30784-8DOI Listing
February 2019
6 Reads
24.690 Impact Factor

R-CHOP without radiation in frontline management of primary mediastinal B-cell lymphoma.

Leuk Lymphoma 2019 May 18;60(5):1261-1265. Epub 2019 Jan 18.

a Department of Oncology , Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine , Baltimore , MD , USA.

Prior to the introduction of rituximab, primary mediastinal B-cell lymphoma (PMBCL) had high rates of treatment failure with cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP), prompting the use of consolidative mediastinal radiation or more intensive chemotherapy regimens. Cure rates improved dramatically with rituximab, but mediastinal radiation was still commonly employed with R-CHOP. We performed a retrospective review of patients treated with R-CHOP alone without radiation for PMBCL. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/10428194.2018.1519812DOI Listing
May 2019
6 Reads

ROS1-rearranged high-PD-L1-expressing lung adenocarcinoma manifesting as mediastinal tumor: A case report.

Oncol Lett 2019 Jan 25;17(1):488-491. Epub 2018 Oct 25.

Division of Thoracic Surgery, Graduate School of Medicine, Kobe University, Kobe, Hyogo 650-0017, Japan.

ROS proto-oncogene 1 receptor tyrosine kinase (ROS1)-rearranged lung cancer is rare and comprises only 1% of lung adenocarcinoma cases. It has recently been reported to have good response to crizotinib, a tyrosine kinase inhibitor of anaplastic lymphoma kinase. Driver oncogene mutations with approved therapies seldom coexist with a high expression of Programmed death-ligand 1 (PD-L1). Read More

View Article

Download full-text PDF

Source
http://www.spandidos-publications.com/10.3892/ol.2018.9622
Publisher Site
http://dx.doi.org/10.3892/ol.2018.9622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313173PMC
January 2019
14 Reads

Mediastinal follicular dendritic cell sarcoma: a rare, potentially under-recognized, and often misdiagnosed disease.

Diagn Pathol 2019 Jan 15;14(1). Epub 2019 Jan 15.

Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.

Background: Mediastinal follicular dendritic cell sarcoma (FDCS) is extremely rare. Due to potential under-recognization of this disease, it happens to be misdiagnosed, especially on core needle biopsy. We report 3 cases of mediastinal FDCS and provide a literature review to improve better understanding of the tumor and to reduce misdiagnosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13000-019-0779-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334468PMC
January 2019
3 Reads

Six-year-old boy with mediastinal mass.

J Pak Med Assoc 2019 Jan;69(1):135

Department of Pediatric Oncology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan.

Lymphoblastic lymphomas account for 20-30% of all non-Hodgkin lymphomas (NHL) in children, and most cases of childhood lymphoblastic lymphoma are T-cell type (T-LL). T-LL occurs most frequently in late childhood and adolescence; with male predominance of 2:1.We present a paediatric case with a right sided mediastinal mass causing mediastinal shift diagnosed as T-LL. Read More

View Article

Download full-text PDF

Source
January 2019
4 Reads

Predictive Factors for Inaccurate Diagnosis of Swollen Lymph Nodes in Endoscopic Ultrasound-Guided Fine Needle Aspiration.

Clin Endosc 2019 Mar 7;52(2):152-158. Epub 2019 Jan 7.

Department of Gastroenterology, Sendai City Medical Center, Sendai, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama, Japan.

Background/aims: This study aimed to identify the predictive factors for inaccurate endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) diagnosis of swollen lymph nodes without rapid on-site cytopathological evaluation.

Methods: Eighty-three consecutive patients who underwent EUS-FNA for abdominal or mediastinal lymph nodes from January 2008 to June 2017 were included from a prospectively maintained EUS-FNA database and retrospectively reviewed. The sensitivity, specificity, and accuracy of EUS-FNA for the detection of neoplastic diseases were calculated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5946/ce.2018.125DOI Listing
March 2019
4 Reads

Six versus eight doses of rituximab in patients with aggressive B cell lymphoma receiving six cycles of CHOP: results from the "Positron Emission Tomography-Guided Therapy of Aggressive Non-Hodgkin Lymphomas" (PETAL) trial.

Ann Hematol 2019 Apr 4;98(4):897-907. Epub 2019 Jan 4.

Klinik für Hämatologie, Universitätsklinikum Essen, Essen, Germany.

Standard first-line treatment of aggressive B cell lymphoma comprises six or eight cycles of cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) plus eight doses of rituximab (R). Whether adding two doses of rituximab to six cycles of R-CHOP is of therapeutic benefit has not been systematically investigated. The Positron Emission Tomography-Guided Therapy of Aggressive Non-Hodgkin Lymphomas (PETAL) trial investigated the ability of [F]-fluorodesoxyglucose PET scanning to guide treatment in aggressive non-Hodgkin lymphomas. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00277-018-3578-0DOI Listing
April 2019
8 Reads

The management of primary mediastinal B-cell lymphoma: a British Society for Haematology Good Practice Paper.

Br J Haematol 2019 May 4;185(3):402-409. Epub 2019 Jan 4.

Department of Medical Oncology, Southampton General Hospital, Southampton, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bjh.15731DOI Listing
May 2019
3 Reads

Secondary Thymoma among Adult Treated For Acute Lymphoblastic Lymphoma/Leukemia: Report of a Case and Review of the Literature.

Open Access Maced J Med Sci 2018 Dec 14;6(12):2373-2375. Epub 2018 Dec 14.

Hematology and Pediatric Oncology Center, Hospital 20 Aout Pediatric, Casablanca, Morocco.

Background: Concomitant thymoma and T- lymphoblastic/leukaemia lymphoma is possible. Secondary thymoma after treatment for T-lymphoblastic/leukaemia lymphoma was also occasionally reported, although this is quite rare.

Case Report: We report a case of 44-year-old women with secondary thymoma after chemotherapy treatment for T Acute Lymphoblastic leukaemia/lymphoma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3889/oamjms.2018.396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311490PMC
December 2018
3 Reads

Crazy paving pattern as a rare radiological manifestation of peripheral T-cell lymphoma (PTCL) with lung involvement: A case report.

Respir Med Case Rep 2018 26;25:253-256. Epub 2018 Sep 26.

3rd Department of Medicine, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

We report on a 70-year old woman with dyspnea, systemic lymphadenopathy and abnormal chest computed tomography (CT) findings. A complete laboratory testing as well as mediastinal tissue sampling via Endobronchial Ultrasound (EBUS)-guided Transbronchial Needle Biopsy (TBNB) did not reveal a definite diagnosis. After experiencing acute respiratory failure which led to intensive care unit, the patient underwent a cervical lymph node biopsy which revealed peripheral T-cell lymphoma not otherwise specified (PTCL-NOS). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.rmcr.2018.09.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308371PMC
September 2018
3 Reads

Dyspnea in Pregnancy: A Case Report of a Third Trimester Mediastinal Mass in Pregnancy.

Am J Case Rep 2018 Dec 28;19:1536-1540. Epub 2018 Dec 28.

Department of Obstetrics, University of Tennessee, Knoxville, TN, USA.

BACKGROUND Dyspnea in pregnancy is common and attributable to a variety of etiologies including normal physiology. The obstetric provider is challenged with distinguishing between physiologic versus pathologic dyspnea. CASE REPORT A 31-year-old G2 P1001 female at 34 weeks gestation presented with dyspnea, tachycardia, and inability to lie supine. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12659/AJCR.910725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322058PMC
December 2018
3 Reads