335 results match your criteria Lymphogranuloma Venereum LGV


Bacterial sexually transmitted infections in France: recent trends and patients' characteristics in 2016.

Euro Surveill 2019 Jan;24(5)

Santé publique France (the French national public health agency), Saint-Maurice, France.

Diagnoses of bacterial sexually transmitted infections (STI) have been increasing in France since their resurgence in the late 1990s. This article presents recent epidemiological trends until 2016 and the patients' characteristics. STI surveillance relies on sentinel networks: a clinician-based network RésIST (clinical, biological and behavioural data for early syphilis and gonorrhoea), the lymphogranuloma venereum (LGV) network (clinical, biological and behavioural data for rectal LGV, and the laboratory networks Rénachla and Rénago (demographic and biological data for chlamydial infections and gonorrhoea, respectively). Read More

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http://dx.doi.org/10.2807/1560-7917.ES.2019.24.5.1800038DOI Listing
January 2019
3 Reads

Lymphogranuloma venereum is on the rise in Belgium among HIV negative men who have sex with men: surveillance data from 2011 until the end of June 2017.

BMC Infect Dis 2018 Dec 20;18(1):689. Epub 2018 Dec 20.

Department of Clinical Sciences, Institute of Tropical Medicine, Nationalestraat 155, 2000, Antwerp, Belgium.

Background: The number of cases of Lymphogranuloma venereum (LGV) is increasing in Europe. The described epidemic is mostly confined to HIV positive men who have sex with men (MSM). However, dissemination of LGV from HIV positive to HIV negative MSM could take place due to the implementation of pre-exposure prophylaxis (PrEP) and subsequent possible decrease in condom use. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-018-3600-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302394PMC
December 2018
5 Reads

Lymphogranuloma venereum presenting as an ulcer on the tongue.

Sex Transm Infect 2018 Dec 15. Epub 2018 Dec 15.

Dermatology Department, Hospital Clínic de Barcelona, Universitat de Barcelona, Barcelona, Spain

Oropharyngeal lymphogranuloma venereum (LGV) is an uncommon presentation and mainly consists of either asymptomatic infections or enlarged cervical lymphadenopathy. According to cross-sectional studies, the prevalence of pharyngeal LGV among men who have sex with men (MSM) seems to be very low. Tissue tropism could explain the difference between rectal and oral mucosa infection frequencies. Read More

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2018-053787
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http://dx.doi.org/10.1136/sextrans-2018-053787DOI Listing
December 2018
11 Reads

Lymphoganuloma venereum in the Western world, 15 years after its re-emergence: new perspectives and research priorities.

Curr Opin Infect Dis 2019 Feb;32(1):43-50

Department of Infectious Diseases, STI Outpatient Clinic, Public Health Service of Amsterdam.

Purpose Of Review: Lymphogranuloma venereum (LGV) is a serious sexually transmitted infection caused by Chlamydia trachomatis. If left untreated LGV can cause irreversible late sequelae. LGV is endemic among a high-risk population of men who have sex with men (MSM), and largely reported in Western metropoles. Read More

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http://dx.doi.org/10.1097/QCO.0000000000000519DOI Listing
February 2019
12 Reads

Lymphogranuloma venereum (LGV) in men who have sex with men (MSM): a re-emerging problem, Malta, 2018.

Euro Surveill 2018 Oct;23(43)

Genitourinary Clinic, Mater Dei Hospital, Msida, Malta.

From 1 January to 30 June 2018, 11 cases of Lymphogranuloma venereum (LGV; all preserved samples (n = 4) genovar L2b) were identified at the Genitourinary Clinic (GUC), Mater Dei Hospital, Msida, Malta. All cases were diagnosed in men who have sex with men (MSM); six participated in three group-sex parties. Here, we describe the outbreak and risk factors associated with LGV diagnoses in MSM in Malta in 2018. Read More

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https://www.eurosurveillance.org/content/10.2807/1560-7917.E
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http://dx.doi.org/10.2807/1560-7917.ES.2018.23.43.1800541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208008PMC
October 2018
4 Reads

[Sexually Transmitted Infections in the Tropics].

Authors:
C Bendick

Hautarzt 2018 Nov;69(11):945-959

Department of Dermatology, Preah Kossamak-Hospital, BP 1006, Phnom Penh, Kambodscha.

Sexually transmitted infections (STI) are common all over the world and the incidence of chlamydia, gonorrhea, syphilis and trichomoniasis alone is estimated at 500 million/year. Of these infections 75% occur in tropical countries in Latin America, sub-Saharan Africa and South as well as Southeast Asia. The bacterial infections chancroid, lymphogranuloma venereum (LGV) and granuloma inguinale (GI, Donovanosis) are termed tropical STI. Read More

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http://link.springer.com/10.1007/s00105-018-4275-6
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http://dx.doi.org/10.1007/s00105-018-4275-6DOI Listing
November 2018
10 Reads

Lymphogranuloma Venereum: An Increasingly Common Anorectal Infection Among Men Who Have Sex With Men Attending New York City Sexual Health Clinics.

Sex Transm Dis 2019 Feb;46(2):e14-e17

Wadsworth Center, New York State Department of Health, Albany, NY.

Using Chlamydia trachomatis anorectal specimens routinely tested for lymphogranuloma venereum (LGV) (2008-2011) and samples of archived specimens tested for LGV (2012-2015), we observed increased LGV positivity among men who have sex with men attending NYC Sexual Health Clinics. Using clinical data, we determined predictors of anorectal LGV that may guide clinical management. Read More

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http://Insights.ovid.com/crossref?an=00007435-201902000-0001
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http://dx.doi.org/10.1097/OLQ.0000000000000921DOI Listing
February 2019
2 Reads

Lymphogranuloma venereum in Spain, 2005-2015: A literature review.

Med Clin (Barc) 2018 Nov 27;151(10):412-417. Epub 2018 Aug 27.

Unidad de Vigilancia del VIH/Sida y Comportamientos de Riesgo, Centro Nacional de Epidemiología, Instituto de Salud Carlos III, Madrid, España.

Lymphogranuloma venereum (LGV) was an unusual disease in Europe until 2003, when several outbreaks among men who have sex with men (MSM) emerged. Since 2015, LGV has been included notifiable disease in Spain. Our aim is to review LGV cases published in Spain from 2005 to 2015. Read More

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http://dx.doi.org/10.1016/j.medcli.2018.05.036DOI Listing
November 2018
3 Reads

Delayed diagnosis of colorectal sexually transmitted diseases due to their resemblance to inflammatory bowel diseases.

Int J Infect Dis 2018 Oct 17;75:34-38. Epub 2018 Aug 17.

Infectious Disease Unit, Sheba Medical Center, Ramat Gan, Israel; Sackler Medical School, Tel Aviv University, Tel Aviv, Israel.

Objective: Sexually transmitted diseases (STDs), mainly lymphogranuloma venereum (LGV), induce colorectal symptoms that may be misdiagnosed as inflammatory bowel disease (IBD). This study describes patients who presented with STDs masquerading as IBD in order to improve understanding of missed diagnosis of colorectal STDs and their association with LGV in Israel.

Methods: This retrospective, descriptive study characterized the clinical, endoscopic, and pathological findings of 16 patients who were diagnosed with a colorectal STD after erroneously being diagnosed with IBD. Read More

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http://dx.doi.org/10.1016/j.ijid.2018.08.004DOI Listing
October 2018
13 Reads

Genital ulcers in an immunocompromised man.

JAAD Case Rep 2018 Aug 14;4(7):619-621. Epub 2018 Jul 14.

The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York.

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http://dx.doi.org/10.1016/j.jdcr.2017.10.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070680PMC
August 2018
2 Reads

Observational study of anorectal Chlamydia trachomatis infections in France through the lymphogranuloma venereum surveillance network, 2010-2015.

Int J STD AIDS 2018 Oct 4;29(12):1215-1224. Epub 2018 Jul 4.

4 Santé Publique France (the French National Public Health Agency), Saint-Maurice, France.

The objective of this article is to describe the epidemiology of lymphogranuloma venereum (LGV) and non-LGV Chlamydia trachomatis anorectal infections in France and to examine the characteristics of the affected populations via a voluntary sentinel surveillance system for LGV between 2010 and 2015. Anorectal samples positive for C. trachomatis (CT) were sent by the participating laboratories to the National Reference Center for CT for LGV identification. Read More

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http://dx.doi.org/10.1177/0956462418785266DOI Listing
October 2018
17 Reads

Multiple recurrent abscesses in a patient with undiagnosed IL-12 deficiency and infection by Burkholderia gladioli.

IDCases 2018 27;12:80-83. Epub 2018 Mar 27.

Division of Infectious Disease, Rhode Island Hospital and The Miriam Hospital, Providence, RI, USA.

We report the occurrence of two severe illnesses experienced by one patient over a 19 year period of time. Both illnesses were characterized by severe inflammation and tissue destruction. Signs and symptoms of the first illness were characteristic of lymphogranuloma venereum (LGV). Read More

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http://dx.doi.org/10.1016/j.idcr.2018.03.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010958PMC

[Clinical polymorphism of anorectal lymphogranuloma venereum in Buenos Aires City].

Medicina (B Aires) 2018;78(3):207-210

Cátedra de Microbiología Clínica, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Argentina.

From 2003 to date there has been a rising number of reports from developed countries on cases of lymphogranuloma venereum with anorectal localization in HIV-infected men who have sex with men. This localization differs from the classical inguinal abscesses which are typical of the disease in the tropics. The objective of this work is to document the presence of anorectal lymphogranuloma venereum in Buenos Aires and to describe its varied clinical manifestations. Read More

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January 2018
3 Reads

[Haemorrhagic proctocolitis as primary manifestation of lymphogranuloma venereum in an HIV-positive male].

Ugeskr Laeger 2018 May;180(20)

This is a case report of lymphogranuloma venereum (LGV) manifesting as haemorrhagic proctocolitis in a homosexual HIV-positive male. The primary symptom was a rectal abscess, which was initially surgically treated and subsequently insufficiently treated with single-dose tablet azithromycin. The patient's symptoms were successfully treated after a 21-day doxycycline regime. Read More

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May 2018
30 Reads

Lymphogranuloma venereum in Quebec: Re-emergence among men who have sex with men.

Can Commun Dis Rep 2018 Feb 1;44(2):55-61. Epub 2018 Feb 1.

Département de microbiologie, infectiologie et immunologie, Université de Montréal, Montréal, QC.

Background: Lymphogranuloma venereum (LGV) is a sexually transmitted infection (STI) caused by genotypes L, L and L. This LGV is associated with significant morbidity and increased risk of HIV transmission. While fewer than two cases per year were reported in Quebec before 2005, LGV emerged in 2005-2006 with 69 cases, followed by a period of low incidence (2007-2012), and subsequent re-emergence since 2013. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864252PMC
February 2018
2 Reads

Lymphogranuloma venereum: a rare and forgotten cause of rectal stricture formation.

Int J STD AIDS 2018 Nov 11;29(11):1133-1135. Epub 2018 May 11.

GU Department, Nottingham City Hospital, Nottingham, UK.

Lymphogranuloma venereum (LGV) is caused by L1, L2 and L3 serovars of Chlamydia trachomatis. The anorectal syndrome caused by LGV is often misdiagnosed as inflammatory bowel disease and may rarely lead to stricture formation. Recurrent stricture formation, despite adequate LGV treatment, has not to our knowledge, previously been reported. Read More

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http://dx.doi.org/10.1177/0956462418773224DOI Listing
November 2018

Proctitis and perirectal abscesses: is there anything else to think about?

Rev Esp Enferm Dig 2018 Jun;110(6):410

Radiodiagnóstico, Hospital General Universitario, Ciudad Real.

Lymphogranuloma venereum (LGV) is a condition caused by invasive serovars of Chlamydia trachomatis. The classical inguinal presentation that is characterized by the development of transient genital ulcer(s) and inguinal or femoral lymphadenopathy has decreased in our environment. At present, infection by this bacterium has emerged as an important cause of proctitis and proctocolitis in men who have sex with other men. Read More

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http://dx.doi.org/10.17235/reed.2018.5500/2018DOI Listing
June 2018
5 Reads

Sexually transmitted diseases of the anus and rectum: Causal agents, coinfections, HIV infection and high-risk sexual behaviour.

Med Clin (Barc) 2019 Feb 19;152(3):98-101. Epub 2018 Apr 19.

Servicio de Dermatología, Hospital Clínic de Barcelona, Universitat de Barcelona, Barcelona, España. Electronic address:

Introduction And Objective: Sexually transmitted infections of the rectum and anus (STI-RA) mainly affect men who have sex with men (MSM). The incidence of STI-RA among them has increased in recent years.

Material And Methods: Retrospective study in patients with diagnoses of STI-RA in an STI unit during the years 2014 and 2015. Read More

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http://dx.doi.org/10.1016/j.medcli.2018.02.014DOI Listing
February 2019
14 Reads

Lymphogranuloma venereum genovar L2b concomitantly with syphilis and hepatitis C in a male patient in Poland – case report

Przegl Epidemiol 2018 ;72(1):45-51

WHO Collaborating Centre for Gonorrhoea and Other STIs, National Reference Laboratory for STIs, Department of Laboratory Medicine, Faculty of Medicine and Health, Ӧrebro University, Ӧrebro,Sweden

We describe the first case of lymphogranuloma venereum (LGV) in Poland, with inguino-femoral lymphadenopathy, diagnosed and successfully treated according to the 2013 European LGV guideline. Chlamydia trachomatis genovar L2b, mainly responsible for the ongoing LGV epidemics among men who have sex with men (MSM) in Western European countries, was confirmed. The case also verified that co-infections with other sexually transmitted infections (syphilis and hepatitis C virus) are frequent in MSM LGV patients, as well as the very large difficulties with contact tracing for these patients. Read More

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January 2018
9 Reads

Lymphogranuloma venereum among patients presenting at the HIV/STI clinic in Antwerp, Belgium : a case series.

Acta Gastroenterol Belg 2017 Jul-Sep;80(3):385-387

Institute of Tropical Medicine, Clinical Sciences.

Objective of this study was to describe the patient characteristics and clinical presentation of laboratory confirmed lymphogranuloma venereum (LGV) cases, diagnosed at the Institute of Tropical Medicine (ITM), Antwerp, Belgium. Demographic and biomedical characteristics of all patients with chlamydia-positive sample results were retrieved for the years 2013 and 2014. Samples were obtained from both symptomatic and asymptomatic patients who consulted at the HIV/STI clinic. Read More

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April 2018
2 Reads

Chlamydia trachomatis in Cervical Lymph Node of Man with Lymphogranuloma Venereum, Croatia, 2014.

Emerg Infect Dis 2018 04;24(4):806-808

We report an HIV-infected person who was treated for lymphogranuloma venereum cervical lymphadenopathy and proctitis in Croatia in 2014. Infection with a variant L2b genovar of Chlamydia trachomatis was detected in a cervical lymph node aspirate. A prolonged course of doxycycline was required to cure the infection. Read More

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http://dx.doi.org/10.3201/eid2404.171872DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875274PMC
April 2018
3 Reads
6.750 Impact Factor

[Haemorrhagic proctocolitis as primary manifestation of lymphogranuloma venereum in an HIV-positive male].

Ugeskr Laeger 2018 Mar;180(11)

This is a case report of lymphogranuloma venereum (LGV) manifesting as haemorrhagic proctocolitis in a homosexual HIV-positive male. The primary symptom was a rectal abscess, which was initially surgically treated and subsequently insufficiently treated with single-dose tablet azithromycin. The patient's symptoms were successfully treated after a 21-day doxycycline regime. Read More

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March 2018
10 Reads

Observed Treatment Responses to Short-Course Doxycycline Therapy for Rectal Lymphogranuloma Venereum in Men Who Have Sex With Men.

Sex Transm Dis 2018 Jun;45(6):406-408

Central and North West London NHS Foundation Trust, London, United Kingdom.

Background: Lymphogranuloma venereum (LGV) has reestablished itself as an endemic sexually transmitted infection in the United Kingdom and elsewhere in Europe and North America over the last decade. Current guidelines suggest treatment with 21 days of doxycycline; however, the evidence base for LGV treatment including its duration is very limited.

Methods: We conducted a retrospective review in 2 central London genitourinary medicine clinics of men who have sex with men (MSM) with LGV in whom less than 21 days of doxycycline was used initially. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000772DOI Listing
June 2018
2 Reads

Plasmid Negative Regulation of CPAF Expression Is Pgp4 Independent and Restricted to Invasive Biovars.

MBio 2018 01 30;9(1). Epub 2018 Jan 30.

National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada

is an obligate intracellular bacterial pathogen that causes blinding trachoma and sexually transmitted disease. isolates are classified into 2 biovars-lymphogranuloma venereum (LGV) and trachoma-which are distinguished biologically by their natural host cell infection tropism. LGV biovars infect macrophages and are invasive, whereas trachoma biovars infect oculo-urogenital epithelial cells and are noninvasive. Read More

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http://dx.doi.org/10.1128/mBio.02164-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790913PMC
January 2018
7 Reads

Asymptomatic lymphogranuloma venereum among Nigerian men who have sex with men.

Sex Transm Infect 2018 12 29;94(8):578-581. Epub 2018 Jan 29.

Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Objectives: Recent outbreaks of anorectal lymphogranuloma venereum (LGV) among men who have sex with men (MSM) have been characterised by proctocolitis requiring extended antibiotic treatment compared with infections caused by other serovars of (CT). We describe the prevalence and clinical features of LGV among Nigerian MSM diagnosed with anorectal CT.

Methods: MSM were recruited for this observational cohort in Lagos, Nigeria, using respondent-driven sampling and screened for HIV and bacterial STIs every three months for up to 18 months. Read More

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http://dx.doi.org/10.1136/sextrans-2017-053414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064673PMC
December 2018
14 Reads

Asymptomatic urethral lymphogranuloma venereum: a case report.

Int J STD AIDS 2018 07 19;29(8):828-830. Epub 2018 Jan 19.

1 Clinique médicale l'Actuel, Montréal, Canada.

Since 2003, there has been a resurgence of lymphogranuloma venereum (LGV), a variant of Chlamydia trachomatis (CT), among men who have sex with men (MSM) in several urban areas of Europe and North America. LGV infection occurs most often at anal sites causing proctitis. Urethral and oropharyngeal infections are rare. Read More

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http://dx.doi.org/10.1177/0956462417751813DOI Listing
July 2018
4 Reads

The Etiology of Genital Ulcer Disease and Coinfections With Chlamydia trachomatis and Neisseria gonorrhoeae in Zimbabwe: Results From the Zimbabwe STI Etiology Study.

Sex Transm Dis 2018 01;45(1):61-68

From the *Zimbabwe Ministry of Health and Child Care; †Department of Community Medicine, University of Zimbabwe, College of Health Sciences, Harare, Zimbabwe; ‡US Centers for Disease Control and Prevention, Zimbabwe and Division of Global HIV/AIDS, CDC, Atlanta, GA; §Fogarty International Center, National Institutes of Health, Bethesda, MD; ¶Zimbabwe Community Health Intervention Research (ZiCHIRe) Project, Harare, Zimbabwe; ∥Western Sydney Sexual Health Centre, Parramatta; **Marie Bashir Institute for Infectious Diseases and Biosecurity & Sydney Medical School-Westmead, University of Sydney, Sydney, New South Wales, Australia; ††School of Medicine, University of Washington, Seattle, WA; ‡‡Colorado School of Public Health, University of Colorado Denver, Denver, CO; §§Rietmeijer Consulting LLC, Denver, CO.

Background: In many countries, sexually transmitted infections (STIs) are treated syndromically. Thus, patients diagnosed as having genital ulcer disease (GUD) in Zimbabwe receive a combination of antimicrobials to treat syphilis, chancroid, lymphogranuloma venereum (LGV), and genital herpes. Periodic studies are necessary to assess the current etiology of GUD and assure the appropriateness of current treatment guidelines. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994235PMC
January 2018
19 Reads

Lymphogranuloma venereum rates increased and Chlamydia trachomatis genotypes changed among men who have sex with men in Sweden 2004-2016.

J Med Microbiol 2017 Nov 12;66(11):1684-1687. Epub 2017 Oct 12.

1​Department of Medical Sciences, Section of Clinical Bacteriology, Uppsala University, Uppsala, Sweden.

This study aimed to determine the incidence of lymphogranuloma venereum (LGV) in Sweden since 2004 and to study in detail a consecutive number of Chlamydia trachomatis cases in men who have sex with men (MSM) during a 10 month period (September 2014 to July 2015). LGV increased from sporadic import cases in 2004 to comprise a spread within Sweden in 2016. Initially, only the L2b ompA genotype was detected, but in 2015 half of the genotyped LGV cases were L2 genotype. Read More

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http://dx.doi.org/10.1099/jmm.0.000597DOI Listing
November 2017
15 Reads

Laboratory Processes for Confirmation of Lymphogranuloma Venereum Infection During a 2015 Investigation of a Cluster of Cases in the United States.

Sex Transm Dis 2017 11;44(11):691-694

From the Division of STD Prevention, CDC, Atlanta, GA.

In September 2015, the Centers for Disease Control and Prevention were notified of a suspected outbreak investigation of lymphogranuloma venereum (LGV) cases by the Michigan Department of Health and Human Services. The Centers for Disease Control and Prevention offered support with a laboratory-developed polymerase chain reaction test for LGV. This note describes the laboratory workflow and procedures used for the laboratory confirmation of LGV infection. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000667DOI Listing
November 2017
12 Reads

LGV serotypes: an update from Milan, Italy.

Sex Transm Infect 2017 09;93(6):395

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

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http://dx.doi.org/10.1136/sextrans-2016-052985DOI Listing
September 2017
25 Reads

A Macaque Model for Rectal Lymphogranuloma Venereum and Non-Lymphogranuloma Venereum Chlamydia trachomatis: Impact on Rectal Simian/Human Immunodeficiency Virus Acquisition.

Sex Transm Dis 2017 09;44(9):551-556

From the *Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention; †Libra Management Group, ‡Division of Sexually Transmitted Disease Prevention, Centers for Disease Control and Prevention, Atlanta, GA; §The DESA group, Columbia, SC; and ¶Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA.

Background: Sustained genital tract inflammation caused by sexually transmitted infections (STIs) is known to increase risk of vaginal human immunodeficiency virus (HIV) infections but, to our knowledge, there are no nonhuman primate studies that have evaluated its link to rectal HIV acquisition.

Methods: Rhesus macaques inoculated with Chlamydia trachomatis (CT) (serovars LGV-L2 and CT-E; n = 7) or saline (n = 7) received up to 20 rectal challenges twice a week of simian/HIV immunodeficiency virus (SHIVSF162p3). SHIV viremia was determined by real-time PCR and Chlamydia infection by APTIMA Combo 2 testing. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000644DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606231PMC
September 2017
42 Reads

Low Prevalence of Urethral Lymphogranuloma Venereum Infections Among Men Who Have Sex With Men: A Prospective Observational Study, Sexually Transmitted Infection Clinic in Amsterdam, the Netherlands.

Sex Transm Dis 2017 09;44(9):547-550

From the *Department of Dermatology/Allergology, University Medical Center Utrecht, Utrecht; †Public Health Service of Amsterdam, STI Outpatient Clinic, Public Health Laboratory, Department of Infectious Diseases; ‡Amsterdam Infection and Immunity Institute, Academic Medical Centre, University of Amsterdam; and §Department of Dermatology, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands.

In contrast to anorectal lymphogranuloma venereum (LGV), few urogenital LGV cases are reported in men who have sex with men. Lymphogranuloma venereum was diagnosed in 0.06% (7/12,174) urine samples, and 0. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559185PMC
September 2017
16 Reads

The first case of lymphogranuloma venereum in a woman in East-Central Europe and its multiple co-infections.

Folia Microbiol (Praha) 2018 Jan 24;63(1):93-95. Epub 2017 Jul 24.

Department of Dermatovenereology, Second Faculty of Medicine, Charles University and Hospital Bulovka, Budinova 2, 180 81, Prague 8, Czech Republic.

We are reporting the first case of lymphogranuloma venereum in women in East-Central Europe. A 22-year-old heterosexual woman attended our department of venereology. She complained about a burning sensation in the urethra and vaginal discharge. Read More

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http://dx.doi.org/10.1007/s12223-017-0538-3DOI Listing
January 2018
25 Reads

Extra-rectal lymphogranuloma venereum in France: a clinical and molecular study.

Sex Transm Infect 2018 02 11;94(1):3-8. Epub 2017 Jul 11.

CHU Bordeaux, Service des Maladies Infectieuses et Tropicales, F-33000 Bordeaux, France.

Objectives: To describe a series of extrarectal lymphogranuloma venereum (LGV) cases diagnosed in France.

Methods: Consecutive LGV cases confirmed at the French Reference Centre for chlamydiae with an extrarectal sample from January 2010 to December 2015 were included. The first part of the study consisted of a retrospective case note review and analysis. Read More

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http://dx.doi.org/10.1136/sextrans-2017-053126DOI Listing
February 2018
12 Reads

Inguinal and anorectal Lymphogranuloma Venereum: a case series from a sexually transmitted disease center in Rome, Italy.

BMC Infect Dis 2017 06 2;17(1):386. Epub 2017 Jun 2.

Clinic of Dermatology and Infectious Diseases (STI/HIV Unit), San Gallicano Dermatological Institute (IFO-IRCCS), Rome, Italy.

Background: Lymphogranuloma venereum (LGV) is a sexually transmitted infection caused by L1, L2, L3 serovars of C. trachomatis (CT). Since 2003, LGV cases have been increasing in Europe. Read More

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http://dx.doi.org/10.1186/s12879-017-2484-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455085PMC
June 2017
21 Reads

Rapid detection and strain typing of Chlamydia trachomatis using a highly multiplexed microfluidic PCR assay.

PLoS One 2017 31;12(5):e0178653. Epub 2017 May 31.

NetBio, Waltham, Massachusetts, United States of America.

Nucleic acid amplification tests (NAATs) are recommended by the CDC for detection of Chlamydia trachomatis (Ct) urogenital infections. Current commercial NAATs require technical expertise and sophisticated laboratory infrastructure, are time-consuming and expensive, and do not differentiate the lymphogranuloma venereum (LGV) strains that require a longer duration of treatment than non-LGV strains. The multiplexed microfluidic PCR-based assay presented in this work simultaneously interrogates 13 loci to detect Ct and identify LGV and non-LGV strain-types. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0178653PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451082PMC
September 2017
29 Reads

Lymphogranuloma Venereum-Serovar L2b Presenting With Painful Genital Ulceration: An Emerging Clinical Presentation?

Sex Transm Dis 2017 05;44(5):310-312

From the *Dermatologie et Vénéréologie, Hopital Saint Louis, Universités Bobigny, Paris, France; †Dermatologie et Vénéréologie, Hopital Hammoud, Beyrouth, Liban; ‡Centre National de Référence des Chlamydiae et des Mycoplasma, Université de Bordeaux, Bordeaux ; and §Dermatologie et Vénéréologie, Hopital Saint Louis, Paris, France.

These 5 cases of atypical inflammatory lymphogranula venereum (LGV) serovar L2b presenting initially with edema and persistent painful ulceration illustrate that clinical manifestations of LGV in the current outbreak in men who have sex with men reflect the influence of both the serovars virulence and the host immune system and are not confined to proctitis. L2b serovar could have a particular high virulence profile, and the need for awareness of LGV as a cause of genital ulceration is crucial. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000597DOI Listing
May 2017
13 Reads

Emergence of the lymphogranuloma venereum L2c genovariant, Hungary, 2012 to 2016.

Euro Surveill 2017 Feb;22(5)

Department of Phage and Molecular Typing, National Centre for Epidemiology, Budapest, Hungary.

In eastern Europe, few countries have so far reported laboratory-confirmed cases of lymphogranuloma venereum (LGV). Here we describe 22 LGV cases in men who have sex with men (MSM) detected in Hungary from November 2012 to July 2016. Sequence analyses show that 16 of these 22 cases were affected by the L2c genovariant, with from 2012 to 2014, one LGV L2c case detected per year, followed by seven cases in 2015 and six up to July 2016. Read More

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http://dx.doi.org/10.2807/1560-7917.ES.2017.22.5.30455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388118PMC
February 2017
10 Reads

Lymphogranuloma venereum proctitis.

Proc (Bayl Univ Med Cent) 2016 Oct;29(4):418-419

Division of Cardiology (Harrison), Department of Internal Medicine (Som, Stroup), Oklahoma State University Medical Center, Tulsa, Oklahoma.

We describe a 60-year-old man who presented with rectal pain and bleeding of a month's duration. His presentation was highly suggestive of lymphogranuloma venereum (LGV) proctitis. Nucleic acid amplification for chlamydia and gonorrhea via rectal swab revealed evidence supportive of anorectal chlamydia. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023305PMC
October 2016
10 Reads

Diagnostic Procedures to Detect Chlamydia trachomatis Infections.

Authors:
Thomas Meyer

Microorganisms 2016 Aug 5;4(3). Epub 2016 Aug 5.

Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf (UKE), Hamburg 20246, Germany.

The intracellular life style of chlamydia and the ability to cause persistent infections with low-grade replication requires tests with high analytical sensitivity to directly detect C. trachomatis (CT) in medical samples. Nucleic acid amplification tests (NAATs) are the most sensitive assays with a specificity similar to cell culture and are considered the method of choice for CT detection. Read More

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http://www.mdpi.com/2076-2607/4/3/25
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039585PMC
http://dx.doi.org/10.3390/microorganisms4030025DOI Listing
August 2016
13 Reads

Notes from the Field: Cluster of Lymphogranuloma Venereum Cases Among Men Who Have Sex with Men - Michigan, August 2015-April 2016.

MMWR Morb Mortal Wkly Rep 2016 Sep 2;65(34):920-1. Epub 2016 Sep 2.

Lymphogranuloma venereum (LGV) is a sexually transmitted disease (STD) caused by infection with invasive Chlamydia trachomatis serovars L1-L3 (1). LGV is characterized by inguinal and/or femoral lymphadenopathy, typically following a transient, self-limited genital ulcer or papule that might go unnoticed. Rectal infection can result in proctocolitis that can present with mucoid and/or hemorrhagic rectal discharge, anal pain, constipation, fever, and tenesmus, and signs of granulomas and/or ulcerations on anoscopy (1,2). Read More

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http://dx.doi.org/10.15585/mmwr.mm6534a6DOI Listing
September 2016
19 Reads

Systematic Review and Meta-Analysis of Doxycycline Efficacy for Rectal Lymphogranuloma Venereum in Men Who Have Sex with Men.

Emerg Infect Dis 2016 10 15;22(10):1778-84. Epub 2016 Oct 15.

Rectal lymphogranuloma venereum (LGV) has reemerged as a sexually transmitted infection among men who have sex with men (MSM), particularly those who are HIV-positive. We undertook a systematic review and meta-analysis to determine the efficacy of doxycycline (100 mg 2×/d for 21 days) for rectal LGV in MSM. Nine studies were included: 4 prospective, 4 retrospective, and 1 combined retrospective and prospective. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038401PMC
http://dx.doi.org/10.3201/eid2210.160986DOI Listing
October 2016
5 Reads

A Case of Reactive Arthritis Associated With Lymphogranuloma Venereum Infection in a Woman.

Sex Transm Dis 2016 09;43(9):584-6

From the *Department of Microbiology, and †Department of Dermatology, DIMES, University of Bologna, Bologna, Italy.

We report the first case of reactive arthritis associated with lymphogranuloma venereum (LGV) in an Italian human immunodeficiency virus-negative woman with urogenital and rectal Chlamydia trachomatis L2 serovar infection. The LGV-associated arthritis has to be considered even when classic symptoms of arthritis are missing and in case of asymptomatic or cryptic LGV localizations. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000482DOI Listing
September 2016
6 Reads

Approach to lymphogranuloma venereum.

Can Fam Physician 2016 Jul;62(7):554-8

Nurse practitioner at the Ottawa Public Health Sexual Health Centre.

Objective: To review the literature about lymphogranuloma venereum (LGV) and to provide an overview and discussion of practice guidelines.

Sources Of Information: The terms Chlamydia trachomatis and lymphogranuloma venereum were searched separately in PubMed. Empirical studies, practice reviews, and clinical guidelines were included. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955081PMC
July 2016
6 Reads

A suspected case of lymphogranuloma venereum (LGV) suggests underdiagnosed LGV infection among Slovenian men who have sex with men.

Acta Dermatovenerol Alp Pannonica Adriat 2016 Jun;25(2):35-7

Zdrav Splet, Lackova cesta 54, Maribor, Slovenia.

Lymphogranuloma venereum (LGV) is sexually transmitted infection caused by serovars of Chlamydia trachomatis, mostly seen among HIV-positive men who have sex with men. The first three reports of possible LGV in Slovenia were from April to June 2015, followed by a confirmed case of LGV in August 2015. We present the case of an HIV-positive MSM that presented with an anorectal abscess, discharge, lymphadenopathy, and unusual perianal plaque. Read More

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June 2016
9 Reads

Anorectal Lymphogranuloma Venereum in Madrid: A Persistent Emerging Problem in Men Who Have Sex With Men.

Sex Transm Dis 2016 07;43(7):414-9

From the *Division of Infectious Diseases, †Departments of Microbiology, ‡Department of Immunology, Fundación Jiménez Díaz, QuironSalud, Universidad Autónoma de Madrid; and §Department of Microbiology. Hospital Ramón y Cajal, Madrid, Spain.

Background: Since 2003, outbreaks of lymphogranuloma venereum (LGV) with anorectal syndrome have been increasingly recognized in many Western countries. All of them have been classified as LGV serovar L2b, mainly occurring in human immunodeficiency virus (HIV)-infected men who have had sex with men (MSM). We describe a series of 26 diagnosed cases of LGV proctitis in downtown Madrid, Spain, in 2014, after implementing routine diagnostic procedures for this disease in symptomatic MSM. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000459DOI Listing
July 2016
25 Reads