2,447 results match your criteria Lymphogranuloma Venereum


Lymphoganuloma venereum in the Western world, 15 years after its re-emergence: new perspectives and research priorities.

Curr Opin Infect Dis 2018 Nov 30. Epub 2018 Nov 30.

Department of Infectious Diseases, STI Outpatient Clinic, Public Health Service of Amsterdam.

Purpose Of Review: Lymphogranuloma venereum (LGV) is a serious sexually transmitted infection caused by Chlamydia trachomatis. If left untreated LGV can cause irreversible late sequelae. LGV is endemic among a high-risk population of men who have sex with men (MSM), and largely reported in Western metropoles. Read More

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November 2018
4 Reads

Lymphogranuloma venereum (LGV) in men who have sex with men (MSM): a re-emerging problem, Malta, 2018.

Euro Surveill 2018 Oct;23(43)

Genitourinary Clinic, Mater Dei Hospital, Msida, Malta.

From 1 January to 30 June 2018, 11 cases of Lymphogranuloma venereum (LGV; all preserved samples (n = 4) genovar L2b) were identified at the Genitourinary Clinic (GUC), Mater Dei Hospital, Msida, Malta. All cases were diagnosed in men who have sex with men (MSM); six participated in three group-sex parties. Here, we describe the outbreak and risk factors associated with LGV diagnoses in MSM in Malta in 2018. Read More

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October 2018
3 Reads

[Sexually Transmitted Infections in the Tropics].

Authors:
C Bendick

Hautarzt 2018 Nov;69(11):945-959

Department of Dermatology, Preah Kossamak-Hospital, BP 1006, Phnom Penh, Kambodscha.

Sexually transmitted infections (STI) are common all over the world and the incidence of chlamydia, gonorrhea, syphilis and trichomoniasis alone is estimated at 500 million/year. Of these infections 75% occur in tropical countries in Latin America, sub-Saharan Africa and South as well as Southeast Asia. The bacterial infections chancroid, lymphogranuloma venereum (LGV) and granuloma inguinale (GI, Donovanosis) are termed tropical STI. Read More

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November 2018
7 Reads

Development of a rapid colorimetric multiplex PCR-reverse line blot for the detection and typing of 14 Chlamydia trachomatis genovars.

J Med Microbiol 2018 Oct 10. Epub 2018 Oct 10.

3​Department of Obstetrics and Gynaecology, University of Melbourne, Australia.

Purpose: Chlamydia trachomatis is responsible for trachoma-associated blindness as well as the most common sexually transmitted bacterial infection worldwide, although the genovars for the former are typically A-C, whilst for the latter they are D-K and for the uncommon infection lymphogranuloma venereum they are L1-3. Nucleotide variations within the ompA gene facilitate the identification of C. trachomatis genovars. Read More

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October 2018
6 Reads

Lymphogranuloma venereum: an increasingly common anorectal infection among men who have sex with men attending New York City Sexual Health Clinics.

Sex Transm Dis 2018 Oct 1. Epub 2018 Oct 1.

New York City Department of Health and Mental Hygiene, Bureau of Sexually Transmitted Infections, Queens, NY.

Using Chlamydia trachomatis anorectal specimens routinely tested for LGV (2008-2011) and samples of archived specimens tested for LGV (2012-2015), we observed increased LGV positivity among men-who-have-sex-with-men attending NYC Sexual Health Clinics. Using clinical data, we determined predictors of anorectal LGV that may guide clinical management. Read More

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October 2018
2 Reads

Atypical lymphogranuloma venereum mimicking an anorectal neoplasm.

Rev Esp Enferm Dig 2018 Oct;110(10):676-677

Hospital do Salnés.

Lymphogranuloma venereum (LV) is a sexually transmitted disease that may have atypical clinical manifestations mimicking tumors or inflammatory conditions, which renders its diagnosis difficult. LV requires both a clinical and endoscopic diagnosis before early treatment may be administered, and should be included as a differential diagnosis for individuals with risk factors. Read More

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October 2018

Lymphogranuloma venereum in Spain, 2005-2015: A literature review.

Med Clin (Barc) 2018 Nov 27;151(10):412-417. Epub 2018 Aug 27.

Unidad de Vigilancia del VIH/Sida y Comportamientos de Riesgo, Centro Nacional de Epidemiología, Instituto de Salud Carlos III, Madrid, España.

Lymphogranuloma venereum (LGV) was an unusual disease in Europe until 2003, when several outbreaks among men who have sex with men (MSM) emerged. Since 2015, LGV has been included notifiable disease in Spain. Our aim is to review LGV cases published in Spain from 2005 to 2015. Read More

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November 2018
2 Reads

Delayed diagnosis of colorectal sexually transmitted diseases due to their resemblance to inflammatory bowel diseases.

Int J Infect Dis 2018 Oct 17;75:34-38. Epub 2018 Aug 17.

Infectious Disease Unit, Sheba Medical Center, Ramat Gan, Israel; Sackler Medical School, Tel Aviv University, Tel Aviv, Israel.

Objective: Sexually transmitted diseases (STDs), mainly lymphogranuloma venereum (LGV), induce colorectal symptoms that may be misdiagnosed as inflammatory bowel disease (IBD). This study describes patients who presented with STDs masquerading as IBD in order to improve understanding of missed diagnosis of colorectal STDs and their association with LGV in Israel.

Methods: This retrospective, descriptive study characterized the clinical, endoscopic, and pathological findings of 16 patients who were diagnosed with a colorectal STD after erroneously being diagnosed with IBD. Read More

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October 2018
9 Reads

Sexual behaviours and sexually transmitted infection outcomes in a cohort of HIV-negative men who have sex with men attending sexual health clinics in England.

Int J STD AIDS 2018 Aug 16:956462418789333. Epub 2018 Aug 16.

1 HIV&STI Department, Centre for Infectious Disease Surveillance and Control, Public Health England, London, UK.

Men who have sex with men (MSM) attending sexual health (SH) clinics are at high risk for HIV acquisition and are disproportionately affected by sexually transmitted infections (STIs). We collected standardised behavioural data from MSM attending clinics to characterise sexual behaviours and identify predictors for HIV and STIs. In 2012-2013, HIV-negative MSM attending five SH clinics in England reported sexual behaviours in the previous three months via a self-administered questionnaire. Read More

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August 2018
11 Reads

Genital ulcers in an immunocompromised man.

JAAD Case Rep 2018 Aug 14;4(7):619-621. Epub 2018 Jul 14.

The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York.

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August 2018
1 Read

Lymphogranuloma Venereum Proctitis.

Clin Gastroenterol Hepatol 2018 Aug 3. Epub 2018 Aug 3.

Gastroenterology Department, Amiens University Hospital, Amiens, France.

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August 2018
3 Reads

Observational study of anorectal Chlamydia trachomatis infections in France through the lymphogranuloma venereum surveillance network, 2010-2015.

Int J STD AIDS 2018 Oct 4;29(12):1215-1224. Epub 2018 Jul 4.

4 Santé Publique France (the French National Public Health Agency), Saint-Maurice, France.

The objective of this article is to describe the epidemiology of lymphogranuloma venereum (LGV) and non-LGV Chlamydia trachomatis anorectal infections in France and to examine the characteristics of the affected populations via a voluntary sentinel surveillance system for LGV between 2010 and 2015. Anorectal samples positive for C. trachomatis (CT) were sent by the participating laboratories to the National Reference Center for CT for LGV identification. Read More

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October 2018
10 Reads

Multiple recurrent abscesses in a patient with undiagnosed IL-12 deficiency and infection by Burkholderia gladioli.

IDCases 2018 27;12:80-83. Epub 2018 Mar 27.

Division of Infectious Disease, Rhode Island Hospital and The Miriam Hospital, Providence, RI, USA.

We report the occurrence of two severe illnesses experienced by one patient over a 19 year period of time. Both illnesses were characterized by severe inflammation and tissue destruction. Signs and symptoms of the first illness were characteristic of lymphogranuloma venereum (LGV). Read More

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[Clinical polymorphism of anorectal lymphogranuloma venereum in Buenos Aires City].

Medicina (B Aires) 2018 ;78(3):207-210

Cátedra de Microbiología Clínica, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Argentina.

From 2003 to date there has been a rising number of reports from developed countries on cases of lymphogranuloma venereum with anorectal localization in HIV-infected men who have sex with men. This localization differs from the classical inguinal abscesses which are typical of the disease in the tropics. The objective of this work is to document the presence of anorectal lymphogranuloma venereum in Buenos Aires and to describe its varied clinical manifestations. Read More

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January 2018
2 Reads

Glycosylation-dependent galectin-receptor interactions promote infection.

Proc Natl Acad Sci U S A 2018 06 11;115(26):E6000-E6009. Epub 2018 Jun 11.

Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas, C1428ADN Buenos Aires, Argentina;

() constitutes the most prevalent sexually transmitted bacterium worldwide. Chlamydial infections can lead to severe clinical sequelae including pelvic inflammatory disease, ectopic pregnancy, and tubal infertility. As an obligate intracellular pathogen, has evolved multiple strategies to promote adhesion and invasion of host cells, including those involving both bacterial and host glycans. Read More

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June 2018
10 Reads

[Haemorrhagic proctocolitis as primary manifestation of lymphogranuloma venereum in an HIV-positive male].

Ugeskr Laeger 2018 May;180(20)

This is a case report of lymphogranuloma venereum (LGV) manifesting as haemorrhagic proctocolitis in a homosexual HIV-positive male. The primary symptom was a rectal abscess, which was initially surgically treated and subsequently insufficiently treated with single-dose tablet azithromycin. The patient's symptoms were successfully treated after a 21-day doxycycline regime. Read More

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May 2018
18 Reads

Lymphogranuloma venereum in Quebec: Re-emergence among men who have sex with men.

Can Commun Dis Rep 2018 Feb 1;44(2):55-61. Epub 2018 Feb 1.

Département de microbiologie, infectiologie et immunologie, Université de Montréal, Montréal, QC.

Background: Lymphogranuloma venereum (LGV) is a sexually transmitted infection (STI) caused by genotypes L, L and L. This LGV is associated with significant morbidity and increased risk of HIV transmission. While fewer than two cases per year were reported in Quebec before 2005, LGV emerged in 2005-2006 with 69 cases, followed by a period of low incidence (2007-2012), and subsequent re-emergence since 2013. Read More

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February 2018
1 Read

Lymphogranuloma venereum: a rare and forgotten cause of rectal stricture formation.

Int J STD AIDS 2018 Nov 11;29(11):1133-1135. Epub 2018 May 11.

GU Department, Nottingham City Hospital, Nottingham, UK.

Lymphogranuloma venereum (LGV) is caused by L1, L2 and L3 serovars of Chlamydia trachomatis. The anorectal syndrome caused by LGV is often misdiagnosed as inflammatory bowel disease and may rarely lead to stricture formation. Recurrent stricture formation, despite adequate LGV treatment, has not to our knowledge, previously been reported. Read More

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November 2018

Proctitis and perirectal abscesses: is there anything else to think about?

Rev Esp Enferm Dig 2018 Jun;110(6):410

Radiodiagnóstico, Hospital General Universitario, Ciudad Real.

Lymphogranuloma venereum (LGV) is a condition caused by invasive serovars of Chlamydia trachomatis. The classical inguinal presentation that is characterized by the development of transient genital ulcer(s) and inguinal or femoral lymphadenopathy has decreased in our environment. At present, infection by this bacterium has emerged as an important cause of proctitis and proctocolitis in men who have sex with other men. Read More

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June 2018
2 Reads

Sexually transmitted diseases of the anus and rectum: Causal agents, coinfections, HIV infection and high-risk sexual behaviour.

Med Clin (Barc) 2018 Apr 18. Epub 2018 Apr 18.

Servicio de Dermatología, Hospital Clínic de Barcelona, Universitat de Barcelona, Barcelona, España. Electronic address:

Introduction And Objective: Sexually transmitted infections of the rectum and anus (STI-RA) mainly affect men who have sex with men (MSM). The incidence of STI-RA among them has increased in recent years.

Material And Methods: Retrospective study in patients with diagnoses of STI-RA in an STI unit during the years 2014 and 2015. Read More

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April 2018
13 Reads

Lymphogranuloma venereum genovar L2b concomitantly with syphilis and hepatitis C in a male patient in Poland – case report

Przegl Epidemiol 2018 ;72(1):45-51

WHO Collaborating Centre for Gonorrhoea and Other STIs, National Reference Laboratory for STIs, Department of Laboratory Medicine, Faculty of Medicine and Health, Ӧrebro University, Ӧrebro,Sweden

We describe the first case of lymphogranuloma venereum (LGV) in Poland, with inguino-femoral lymphadenopathy, diagnosed and successfully treated according to the 2013 European LGV guideline. Chlamydia trachomatis genovar L2b, mainly responsible for the ongoing LGV epidemics among men who have sex with men (MSM) in Western European countries, was confirmed. The case also verified that co-infections with other sexually transmitted infections (syphilis and hepatitis C virus) are frequent in MSM LGV patients, as well as the very large difficulties with contact tracing for these patients. Read More

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January 2018
6 Reads

Lymphogranuloma Venereum Treatment and Terminology.

Sex Transm Dis 2018 Jun;45(6):409-411

From the University of Washington Center for AIDS and STD, Harborview Medical Center, Seattle, WA.

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Trends in the relative prevalence of genital ulcer disease pathogens and association with HIV infection in Johannesburg, South Africa, 2007-2015.

PLoS One 2018 4;13(4):e0194125. Epub 2018 Apr 4.

Marie Bashir Institute for Infectious Diseases and Biosecurity, University of Sydney, Sydney, Australia.

Background: In South Africa, treatment of genital ulcer disease (GUD) occurs in the context of syndromic management. GUD aetiological studies have been conducted in Johannesburg since 2007. We report on GUD pathogen prevalence, sero-prevalence of STI co-infections and aetiological trends among GUD patients presenting to a community-based primary healthcare facility in Johannesburg over a 9-year period. Read More

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July 2018
6 Reads

Lymphogranuloma venereum among patients presenting at the HIV/STI clinic in Antwerp, Belgium : a case series.

Acta Gastroenterol Belg 2017 Jul-Sep;80(3):385-387

Institute of Tropical Medicine, Clinical Sciences.

Objective of this study was to describe the patient characteristics and clinical presentation of laboratory confirmed lymphogranuloma venereum (LGV) cases, diagnosed at the Institute of Tropical Medicine (ITM), Antwerp, Belgium. Demographic and biomedical characteristics of all patients with chlamydia-positive sample results were retrieved for the years 2013 and 2014. Samples were obtained from both symptomatic and asymptomatic patients who consulted at the HIV/STI clinic. Read More

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Proctocolitis caused by lymphogranuloma venereum.

CMAJ 2018 Mar;190(11):E331-E333

Immunodeficiency Clinic, Department of Medicine, University Health Network, Toronto, Ont.

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March 2018
1 Read

Chlamydia trachomatis in Cervical Lymph Node of Man with Lymphogranuloma Venereum, Croatia, 2014.

Emerg Infect Dis 2018 04;24(4):806-808

We report an HIV-infected person who was treated for lymphogranuloma venereum cervical lymphadenopathy and proctitis in Croatia in 2014. Infection with a variant L2b genovar of Chlamydia trachomatis was detected in a cervical lymph node aspirate. A prolonged course of doxycycline was required to cure the infection. Read More

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April 2018
2 Reads
6.750 Impact Factor

Unusual case of a rectal tumour.

BMJ Case Rep 2018 Mar 15;2018. Epub 2018 Mar 15.

Epsom and Saint Helier University Hospitals NHS Trust, Carshalton, UK.

A 48-year-old man presented as an emergency with a 3-week history of rectal bleeding. Examination of his rectum revealed a circumferential tumour, 2 cm from the anal verge. An MRI scan reported a locally infiltrative mid-lower rectal tumour staged as T3d/T4 N2 MX. Read More

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March 2018
4 Reads

[Haemorrhagic proctocolitis as primary manifestation of lymphogranuloma venereum in an HIV-positive male].

Ugeskr Laeger 2018 Mar;180(11)

This is a case report of lymphogranuloma venereum (LGV) manifesting as haemorrhagic proctocolitis in a homosexual HIV-positive male. The primary symptom was a rectal abscess, which was initially surgically treated and subsequently insufficiently treated with single-dose tablet azithromycin. The patient's symptoms were successfully treated after a 21-day doxycycline regime. Read More

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March 2018
7 Reads

Observed Treatment Responses to Short-Course Doxycycline Therapy for Rectal Lymphogranuloma Venereum in Men Who Have Sex With Men.

Sex Transm Dis 2018 Jun;45(6):406-408

Central and North West London NHS Foundation Trust, London, United Kingdom.

Background: Lymphogranuloma venereum (LGV) has reestablished itself as an endemic sexually transmitted infection in the United Kingdom and elsewhere in Europe and North America over the last decade. Current guidelines suggest treatment with 21 days of doxycycline; however, the evidence base for LGV treatment including its duration is very limited.

Methods: We conducted a retrospective review in 2 central London genitourinary medicine clinics of men who have sex with men (MSM) with LGV in whom less than 21 days of doxycycline was used initially. Read More

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June 2018
1 Read

Plasmid Negative Regulation of CPAF Expression Is Pgp4 Independent and Restricted to Invasive Biovars.

MBio 2018 01 30;9(1). Epub 2018 Jan 30.

National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada

is an obligate intracellular bacterial pathogen that causes blinding trachoma and sexually transmitted disease. isolates are classified into 2 biovars-lymphogranuloma venereum (LGV) and trachoma-which are distinguished biologically by their natural host cell infection tropism. LGV biovars infect macrophages and are invasive, whereas trachoma biovars infect oculo-urogenital epithelial cells and are noninvasive. Read More

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January 2018
5 Reads

Asymptomatic lymphogranuloma venereum among Nigerian men who have sex with men.

Sex Transm Infect 2018 Dec 29;94(8):578-581. Epub 2018 Jan 29.

Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Objectives: Recent outbreaks of anorectal lymphogranuloma venereum (LGV) among men who have sex with men (MSM) have been characterised by proctocolitis requiring extended antibiotic treatment compared with infections caused by other serovars of (CT). We describe the prevalence and clinical features of LGV among Nigerian MSM diagnosed with anorectal CT.

Methods: MSM were recruited for this observational cohort in Lagos, Nigeria, using respondent-driven sampling and screened for HIV and bacterial STIs every three months for up to 18 months. Read More

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December 2018
9 Reads

Asymptomatic urethral lymphogranuloma venereum: a case report.

Int J STD AIDS 2018 Jul 19;29(8):828-830. Epub 2018 Jan 19.

1 Clinique médicale l'Actuel, Montréal, Canada.

Since 2003, there has been a resurgence of lymphogranuloma venereum (LGV), a variant of Chlamydia trachomatis (CT), among men who have sex with men (MSM) in several urban areas of Europe and North America. LGV infection occurs most often at anal sites causing proctitis. Urethral and oropharyngeal infections are rare. Read More

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July 2018
3 Reads

The Etiology of Genital Ulcer Disease and Coinfections With Chlamydia trachomatis and Neisseria gonorrhoeae in Zimbabwe: Results From the Zimbabwe STI Etiology Study.

Sex Transm Dis 2018 01;45(1):61-68

From the *Zimbabwe Ministry of Health and Child Care; †Department of Community Medicine, University of Zimbabwe, College of Health Sciences, Harare, Zimbabwe; ‡US Centers for Disease Control and Prevention, Zimbabwe and Division of Global HIV/AIDS, CDC, Atlanta, GA; §Fogarty International Center, National Institutes of Health, Bethesda, MD; ¶Zimbabwe Community Health Intervention Research (ZiCHIRe) Project, Harare, Zimbabwe; ∥Western Sydney Sexual Health Centre, Parramatta; **Marie Bashir Institute for Infectious Diseases and Biosecurity & Sydney Medical School-Westmead, University of Sydney, Sydney, New South Wales, Australia; ††School of Medicine, University of Washington, Seattle, WA; ‡‡Colorado School of Public Health, University of Colorado Denver, Denver, CO; §§Rietmeijer Consulting LLC, Denver, CO.

Background: In many countries, sexually transmitted infections (STIs) are treated syndromically. Thus, patients diagnosed as having genital ulcer disease (GUD) in Zimbabwe receive a combination of antimicrobials to treat syphilis, chancroid, lymphogranuloma venereum (LGV), and genital herpes. Periodic studies are necessary to assess the current etiology of GUD and assure the appropriateness of current treatment guidelines. Read More

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January 2018
15 Reads

Strain Types Have Diversified Regionally and Globally with Evidence for Recombination across Geographic Divides.

Front Microbiol 2017 13;8:2195. Epub 2017 Nov 13.

UCSF Benioff Children's Hospital Oakland Research Institute, Oakland, CA, United States.

() is the leading cause of bacterial sexually transmitted diseases worldwide. The Multi Locus Sequence Typing (MLST) scheme is effective in differentiating strain types (ST), deciphering transmission patterns and treatment failure, and identifying recombinant strains. Here, we analyzed 323 reference and clinical samples, including 58 samples from Russia, an area that has not previously been represented in typing schemes, to expand our knowledge of the global diversification of STs. Read More

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November 2017
7 Reads

Cervical lymphadenopathy due to infection.

Sex Transm Infect 2017 12;93(8):589

Division of Infectious Diseases, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

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December 2017
8 Reads

[Diagnostic issues of lymphogranuloma venereum: A case series of 5 patients].

Rev Med Interne 2017 Dec 8;38(12):794-799. Epub 2017 Nov 8.

Service de médecine interne, hôpital Ambroise-Paré, AP-HP, 92100 Boulogne-Billancourt, France. Electronic address:

Introduction: Lymphogranuloma venereum (LG) is a sexually transmitted infection (STI) caused by Chlamydia trachomatis L serovar.

Methods: These five consecutive cases aim to highlight the risk of LG misdiagnosis, in case of initial presentation with isolated inguinal adenitis.

Results: Five men (mean age: 30±7 years) were seen in an internal medicine department, for inguinal adenopathy. Read More

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December 2017
3 Reads

Chlamydia trachomatis Biovar L2 Infection in Women in South Africa.

Emerg Infect Dis 2017 11;23(11):1913-1915

We detected Chlamydia trachomatis biovar L2 in vaginal swab specimens of 7 women with vaginal discharge in South Africa. Whole-genome sequencing directly from clinical specimens identified a closely related cluster of strains. The clinical role of this infection in the context of syndromic management should be clarified. Read More

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November 2017
5 Reads

Lymphogranuloma venereum rates increased and Chlamydia trachomatis genotypes changed among men who have sex with men in Sweden 2004-2016.

J Med Microbiol 2017 Nov 12;66(11):1684-1687. Epub 2017 Oct 12.

1​Department of Medical Sciences, Section of Clinical Bacteriology, Uppsala University, Uppsala, Sweden.

This study aimed to determine the incidence of lymphogranuloma venereum (LGV) in Sweden since 2004 and to study in detail a consecutive number of Chlamydia trachomatis cases in men who have sex with men (MSM) during a 10 month period (September 2014 to July 2015). LGV increased from sporadic import cases in 2004 to comprise a spread within Sweden in 2016. Initially, only the L2b ompA genotype was detected, but in 2015 half of the genotyped LGV cases were L2 genotype. Read More

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November 2017
14 Reads

Acquisition of wild-type HIV-1 infection in a patient on pre-exposure prophylaxis with high intracellular concentrations of tenofovir diphosphate: a case report.

Lancet HIV 2017 11 14;4(11):e522-e528. Epub 2017 Sep 14.

Department of Infectious Diseases, Amsterdam Infection and Immunity Institute (AI&II), Academic Medical Center, University of Amsterdam, Netherlands; Department of Global Health and Amsterdam Institute for Global Health and Development, Academic Medical Center, University of Amsterdam, Netherlands.

Background: Pre-exposure prophylaxis (PrEP) with emtricitabine and tenofovir disoproxil fumarate is highly effective against acquisition of HIV infection, and only two cases of infection with a multidrug-resistant virus have been reported under adequate long-term adherence, as evidenced by tenofovir diphosphate concentrations in dried blood spots. We report a case of wild-type HIV-1 infection despite consistent use of emtricitabine and tenofovir disoproxil fumarate.

Methods: The patient participated in the Amsterdam PrEP project, a demonstration project of daily and event-driven PrEP. Read More

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November 2017
24 Reads

Frequency and genotypes of Chlamydia trachomatis in patients attending the obstetrics and gynecology clinics in Jalisco, Mexico and correlation with sociodemographic, behavioral, and biological factors.

BMC Womens Health 2017 Sep 15;17(1):83. Epub 2017 Sep 15.

Servicio de Gastroenterología, Hospital Universitario Dr. Jose Eleuterio Gonzalez, Universidad Autónoma de Nuevo León, Av. Gonzalitos and Madero, Mitras Centro PC, 64460, Monterrey, Nuevo León, Mexico.

Background: Chlamydia trachomatis is the causative agent of the most common bacterial sexually transmitted infection worldwide. The aim of this study was to investigate the frequency and genotypes of C. trachomatis in patients attending an obstetrics and gynecology clinic in Jalisco, Mexico and correlates them with sociodemographic, behavioral, and biological factors. Read More

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September 2017
35 Reads

Laboratory Processes for Confirmation of Lymphogranuloma Venereum Infection During a 2015 Investigation of a Cluster of Cases in the United States.

Sex Transm Dis 2017 11;44(11):691-694

From the Division of STD Prevention, CDC, Atlanta, GA.

In September 2015, the Centers for Disease Control and Prevention were notified of a suspected outbreak investigation of lymphogranuloma venereum (LGV) cases by the Michigan Department of Health and Human Services. The Centers for Disease Control and Prevention offered support with a laboratory-developed polymerase chain reaction test for LGV. This note describes the laboratory workflow and procedures used for the laboratory confirmation of LGV infection. Read More

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November 2017
7 Reads

CME.

Praxis (Bern 1994) 2017 Aug;106(17):911-918

1 Klinik und Poliklinik für Innere Medizin, Universitätsspital Zürich.

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August 2017
14 Reads

LGV serotypes: an update from Milan, Italy.

Sex Transm Infect 2017 09;93(6):395

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

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September 2017
21 Reads

A Macaque Model for Rectal Lymphogranuloma Venereum and Non-Lymphogranuloma Venereum Chlamydia trachomatis: Impact on Rectal Simian/Human Immunodeficiency Virus Acquisition.

Sex Transm Dis 2017 09;44(9):551-556

From the *Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention; †Libra Management Group, ‡Division of Sexually Transmitted Disease Prevention, Centers for Disease Control and Prevention, Atlanta, GA; §The DESA group, Columbia, SC; and ¶Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA.

Background: Sustained genital tract inflammation caused by sexually transmitted infections (STIs) is known to increase risk of vaginal human immunodeficiency virus (HIV) infections but, to our knowledge, there are no nonhuman primate studies that have evaluated its link to rectal HIV acquisition.

Methods: Rhesus macaques inoculated with Chlamydia trachomatis (CT) (serovars LGV-L2 and CT-E; n = 7) or saline (n = 7) received up to 20 rectal challenges twice a week of simian/HIV immunodeficiency virus (SHIVSF162p3). SHIV viremia was determined by real-time PCR and Chlamydia infection by APTIMA Combo 2 testing. Read More

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September 2017
27 Reads

Low Prevalence of Urethral Lymphogranuloma Venereum Infections Among Men Who Have Sex With Men: A Prospective Observational Study, Sexually Transmitted Infection Clinic in Amsterdam, the Netherlands.

Sex Transm Dis 2017 09;44(9):547-550

From the *Department of Dermatology/Allergology, University Medical Center Utrecht, Utrecht; †Public Health Service of Amsterdam, STI Outpatient Clinic, Public Health Laboratory, Department of Infectious Diseases; ‡Amsterdam Infection and Immunity Institute, Academic Medical Centre, University of Amsterdam; and §Department of Dermatology, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands.

In contrast to anorectal lymphogranuloma venereum (LGV), few urogenital LGV cases are reported in men who have sex with men. Lymphogranuloma venereum was diagnosed in 0.06% (7/12,174) urine samples, and 0. Read More

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September 2017
14 Reads

Global survey of mRNA levels and decay rates of trachoma and lymphogranuloma venereum biovars.

Heliyon 2017 Jul 26;3(7):e00364. Epub 2017 Jul 26.

Reference Laboratory of Bacterial Sexually Transmitted Infections, Department of Infectious Diseases, National Institute of Health, Lisbon, Portugal.

Interpreting the intricate bacterial transcriptomics implies understanding the dynamic relationship established between transcription and the degradation of transcripts. Here, we performed a comparative overview of gene expression levels and mRNA decay rates for different-biovar (trachoma and lymphogranuloma venereum) strains of the obligate intracellular bacterium . By using RNA-sequencing to measure gene expression levels at mid developmental stage and mRNA decay rates upon rifampicin-based transcription blockage, we observed that: ) 60-70% of the top-50 expressed genes encode proteins with unknown function and proteins involved in "Translation, ribosomal structure and biogenesis" for all strains; ) the expression ranking by genes' functional categories was in general concordant among different-biovar strains; ) the median of the half-life time (t) values of transcripts were 15-17 min, indicating that the degree of transcripts' stability seems to correlate with the bacterial intracellular life-style, as these values are considerably higher than the ones observed in other studies for facultative intracellular and free-living bacteria; ) transcript decay rates were highly heterogeneous within each strain and did not correlate with steady-state expression levels; ) only at very few instances (essentially at gene functional category level) was possible to unveil dissimilarities potentially underlying phenotypic differences between biovars. Read More

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July 2017
3 Reads

The first case of lymphogranuloma venereum in a woman in East-Central Europe and its multiple co-infections.

Folia Microbiol (Praha) 2018 Jan 24;63(1):93-95. Epub 2017 Jul 24.

Department of Dermatovenereology, Second Faculty of Medicine, Charles University and Hospital Bulovka, Budinova 2, 180 81, Prague 8, Czech Republic.

We are reporting the first case of lymphogranuloma venereum in women in East-Central Europe. A 22-year-old heterosexual woman attended our department of venereology. She complained about a burning sensation in the urethra and vaginal discharge. Read More

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January 2018
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Eosinophilic hyperplastic lymphogranuloma: Clinical diagnosis and treatment experience of 41 cases.

Am J Otolaryngol 2017 Sep - Oct;38(5):626-629. Epub 2017 Jul 12.

Department of otolaryngology, Hubei Material and Child Health Hospital, Wuhan, China.

Purpose: The purpose of this study was to investigate the clinical features of eosinophilic hyperplastic lymphogranuloma (EHLG) in the head and neck.

Materials And Methods: Collecting the patients who diagnose with EHLG by pathological examination. The EHLG patients with the masses involved regions, such as involved inguinal region, chest wall, abdominal wall, anterior superior iliac spine or clavicle, instead of head and neck were excluding. Read More

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June 2018
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