1,775 results match your criteria Lymphocytoma Cutis
Contact Dermatitis 2018 Dec 5. Epub 2018 Dec 5.
Department of Dermatology, Hospital Universitario Príncipe de Asturias, Madrid, Spain.
Upper eyelid gold weight implants are an established tool in the symptomatic treatment of lagophthalmos, the inability to close your eyes completely. Complications associated to this procedure are infrequent. When noted, non-infectious inflammatory reactions corresponding to type IV hypersensitivity reactions are resolved with the removal of the implant. Read More
Open Forum Infect Dis 2018 Nov 17;5(11):ofy259. Epub 2018 Oct 17.
Palo Alto Medical Foundation Toxoplasma Serology Laboratory, National Reference Center for the Study and Diagnosis of Toxoplasmosis, Palo Alto, California.
We report the case of a 65-year-old patient with pseudolymphoma who developed acute toxoplasmosis following 6 cycles of rituximab and bendamustine therapy. Acute toxoplasmosis in the setting of biological response modifiers, rather than reactivation, is a unique unreported infection. The patient developed severe disease with multi-organ involvement, including retinitis, myocarditis, and myositis. Read More
Eur J Clin Microbiol Infect Dis 2018 Nov 19. Epub 2018 Nov 19.
University Hospital "Dr. Jose Eleuterio Gonzalez", Department of Dermatology, Universidad Autonoma de Nuevo Leon, Av. Madero y Gonzalitos s/n, Colonia Mitras Centro, 64460, Monterrey, NL, Mexico.
Lyme disease (borreliosis) is one of the most common vector-borne diseases worldwide. Its incidence and geographic expansion has been steadily increasing in the last decades. Lyme disease is caused by Borrelia burgdorferi sensu lato, a heterogeneous group of which three genospecies have been systematically associated to Lyme disease: B. Read More
J Cutan Pathol 2018 Nov 8. Epub 2018 Nov 8.
Department of Dermatology and Allergology, Klinikum Bremen-Mitte, Bremen, Germany.
A 42-year-old Caucasian man suffered from disseminated plaques and ulcerated nodules for 6 weeks. He had weight loss and generalized lymphadenopathy. Underlying diseases were not known up till then. Read More
Cutis 2018 Sep;102(3):E31-E34
Department of Dermatopathology, Western University of Health Sciences, Pomona, California, USA.
Primary cutaneous diffuse large B-cell lymphoma, leg type (DLBCLLT) is a rare, intermediately aggressive form of primary cutaneous B-cell lymphoma (CBCL) that is characterized by the presence of large round cells on histopathology. Clinically, patients present with red-brown nodules on the distal legs. The prognosis is less favorable than other types of CBCLs, with a 5-year survival rate of 50%. Read More
Blood 2018 Oct;132(17):1859
University of Arkansas for Medical Sciences.
BMJ Case Rep 2018 Oct 21;2018. Epub 2018 Oct 21.
Affiliated Dermatology, Scottsdale, Arizona, USA.
J Cutan Pathol 2018 Oct 16. Epub 2018 Oct 16.
University of Washington Division of Dermatology, Seattle, Washington.
We present a case of a widespread fixed drug eruption histologically mimicking CD8 positive cutaneous T-cell lymphoma (CTCL). CTCL has several potential histological and clinical mimics, and accurate diagnosis relies on a combination of clinicopathological correlation and molecular studies. We add generalized fixed drug eruption to the list of possible CTCL mimics. Read More
Pediatr Dermatol 2018 Oct 15. Epub 2018 Oct 15.
Department of Pathology & Laboratory Medicine, Weill Cornell Medicine, New York, New York.
Acral pseudolymphomatous angiokeratoma of children (APACHE) and unilesional mycosis fungoides (MF) are two rare dermatoses in the pediatric population which may have overlapping clinical and histopathologic features, making differentiation between these two diagnoses difficult. We present two similar cases of a solitary plaque on the thigh of a child, one representing APACHE and the other representing unilesional MF with granulomatous features, and we provide a brief overview of the clinical and histopathologic features of APACHE and unilesional MF. Read More
Ear Nose Throat J 2018 Jul;97(7):193-194
Department of Otolaryngology-Head and Neck Surgery, Wake Forest Baptist Medical Center, Winston Salem, NC, USA.
Vet Clin North Am Equine Pract 2018 Aug;34(2):313-343
Newmarket-Indialantic Equine, Newmarket, NH, USA. Electronic address:
Given the variable clinical signs attributed to Borrelia burgdorferi, including infectious arthritis, neurologic disease, and behavioral changes, B burgdorferi is an important differential for decreased performance in sport horses. The primary vectors (Ixodes tick species) are expanding their range and thus Borrelia species are located in a wider area, making exposure more likely. Due to regionally high seroprevalence and vague clinical signs, diagnosis of Lyme disease in the horse is believed overestimated. Read More
Int J Surg Case Rep 2018 28;49:136-139. Epub 2018 Jun 28.
Department of Digestive Surgery, Nagano Municipal Hospital, Nagano, 381-8551, Japan.
Introduction: Pseudolymphoma of the liver is a very rare disease. It is usually resected and pathologically diagnosed because of the difficulty of discrimination from the malignant neoplasm. For this reason, few cases which were observed for several years have been reported. Read More
Appl Immunohistochem Mol Morphol 2018 Jul;26(6):411-419
Department of Pathology, University of Valencia, Valencia, Spain.
High-endothelial venules are a common feature of 3 types of cutaneous pseudolymphomas: pretibial lymphoplasmacytic plaque (PLP) of children, acral pseudolymphomatous angiokeratoma of children (APACHE), and T-cell rich angiomatoid polypoid pseudolymphoma (TRAPP). In addition, primary cutaneous angioplasmacellular hyperplasia (PCAH) overlaps with these other 3 conditions. We intend to study the expression of peripheral node addressins in PLP, APACHE, TRAPP, and PCAH. Read More
J Investig Allergol Clin Immunol 2018 Jun;28(3):199-201
Allergology Section, Hospital General Universitario de Ciudad Real, Spain.
Case Rep Gastroenterol 2016 Sep-Dec;10(3):826-835. Epub 2017 Dec 21.
Department of Surgery, Hyogo College of Medicine, Nishinomiya, Japan.
A 69-year-old woman with chronic hepatitis B was admitted to our hospital with a hepatic tumor. The levels of 2 tumor markers, carcinoembryonic antigen and carbohydrate antigen 19-9, were slightly elevated; however, the α-fetoprotein and protein levels induced by vitamin K antagonist II were within the normal limits. Abdominal ultrasonography showed a well-defined peripheral hypoechoic mass that was isoechoic and homogeneous on the inside. Read More
J Pathol Transl Med 2018 Jul 15;52(4):211-218. Epub 2018 Jun 15.
Department of Pathology and Translational Genomics, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Background: Pulmonary nodular lymphoid hyperplasia (PNLH) is a non-neoplastic pulmonary lymphoid disorder that can be mistaken for malignancy on radiography. Herein, we present nine cases of PNLH, emphasizing clinicoradiological findings and histological features.
Methods: We analyzed radiological and clinicopathological features from the electronic medical records of nine patients (eight females and one male) diagnosed with PNLH. Read More
Acta Cytol 2018 15;62(3):204-208. Epub 2018 May 15.
Background: Enlarged lymph nodes in adult patients often present a diagnostic challenge. In the absence of granuloma or necrosis, the cytology/tissue findings are misleading and relate the enlarged lymph nodes to reactive lymphoid hyperplasia (RLH), because granuloma formation is an immunological response that usually takes 14-100 days to develop. This study assesses the role of real-time (RT)-PCR in the diagnosis of the Mycobacterium complex (MTBC) in lymph node aspirates compared with culture in cases of RLH. Read More
Postepy Dermatol Alergol 2018 Apr 24;35(2):225-226. Epub 2018 Apr 24.
Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Wroclaw, Poland.
Clin Exp Rheumatol 2018 Jan-Feb;36 Suppl 110(1):10-24. Epub 2018 May 3.
Paediatric Clinic, University of Brescia and ASST Spedali Civili di Brescia, Italy.
Fever of unknown origin (FUO) can be caused by a wide group of diseases, and can include both benign and serious conditions. Since the first definition of FUO in the early 1960's, several updates to the definition, diagnostic and therapeutic approaches have been proposed. This review outlines a case report of an elderly Italian male patient with high fever and migrating arthralgia who underwent many procedures and treatments before a final diagnosis of Adult-onset Still's disease was achieved. Read More
JAAD Case Rep 2018 Apr 28;4(3):245-247. Epub 2018 Feb 28.
Division of Dermatology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.
CMAJ 2018 Apr;190(13):E398
Faculty of Medicine (Zhou), University of Ottawa, Ottawa, Ont.; Division of Dermatology (Mistry), Department of Medicine, University of Toronto, Toronto, Ont.
Acta Cytol 2018 29;62(2):93-98. Epub 2018 Mar 29.
Department of Surgery, Kuma Hospital, Kobe, Japan.
Objective: To identify cytological differences between mucosa-associated lymphoid tissue lymphoma (MALT-L) and nonneoplastic lymphocytes using thyroid liquid-based cytology (LBC).
Study Design: We observed LBC and conventional specimens from 35 MALT-L cases, 3 diffuse large B-cell cell lymphoma (DLBCL) cases, and 44 prominent nonneoplastic lymphocytic infiltration cases.
Results: In MALT-L cases, the incidence of lymphoglandular bodies in the LBC specimens was lower than that in the conventional specimens (p < 0. Read More
Acta Gastroenterol Belg 2017 Jul-Sep;80(3):405-410
Internal Medicine Department, Faculty of Medicine, Cairo University, Egypt.
Nodular lymphoid hyperplasia (NLH) is a rare benign condition that is characterized by diffuse hyperplasia of the lymphoid follicles of the gastrointestinal tract (GIT). During endoscopy, NLH appears as multiple or occasionally innumerable nodules measuring a few millimeters in diameter. NLH occurs mainly in the small intestine, less commonly in the large intestine and rarely involves the stomach. Read More
Zhongguo Dang Dai Er Ke Za Zhi 2018 Mar;20(3):214-217
Department of Pediatrics, First Affiliated Hospital of Hunan Normal University/Hunan Provincial People's Hospital, Changsha 410005, China.
Objective: To study the difference in expression of TOPK/PBK in lymph nodes between children with malignant lymphoma and those with reactive lymphoid hyperplasia.
Methods: Eighty children with malignant lymphoma and twenty children with reactive lymphoid hyperplasia were enrolled as subjects. Immunohistochemistry was used to determine the expression of TOPK/PBK in all the subjects. Read More
J Eur Acad Dermatol Venereol 2018 Sep 18;32(9):e358-e360. Epub 2018 May 18.
Department of Dermatology and Venereology, I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation.
J Dtsch Dermatol Ges 2018 Apr 9;16(4):465-467. Epub 2018 Mar 9.
Dermatology Department, Hospital Santo António dos Capuchos, Centro Hospitalar Lisboa Central, Lisbon, Portugal.
Clin Nucl Med 2018 May;43(5):e166-e169
Hepatic pseudolymphoma, also known as reactive lymphoid hyperplasia or nodular lymphoid hyperplasia, is a rare benign lymphoproliferative lesion. Preoperative diagnosis of hepatic pseudolymphoma is challenging. We present 2 cases of hepatic pseudolymphoma with focal intense FDG uptake on FDG PET/CT mimicking malignancy. Read More
Eur Rev Med Pharmacol Sci 2018 Feb;22(4):1051-1060
Department of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Objective: B lymphoma is a type of malignant tumor originating from the lymphatic hematopoietic system. The pathogenesis and treatment methods are not clear. The change of oxidative stress is closely related to the cell DNA damage and cell apoptosis, which may be served as a target for cancer treatment. Read More
Clin Nucl Med 2018 May;43(5):354-355
A 38-year-old man with sigmoid colon cancer underwent a preoperative contrast-enhanced CT which incidentally revealed a modestly enhancing splenic mass. FDG PET/CT showed mildly increased uptake in the splenic lesion in contrast to prominently increased uptake in the colonic tumor. In addition, the splenic mass demonstrated only slightly increased signal intensity in diffusion-weighted MRI, suggesting low probability of metastasis. Read More
J Invest Dermatol 2018 Jul 23;138(7):1573-1581. Epub 2018 Feb 23.
Comprehensive Cancer Center Mainfranken, University of Würzburg, Würzburg, Germany; Department of Dermatology, Venereology and Allergology and Skin Cancer Center, University Hospital Würzburg, Würzburg, Germany.
Primary cutaneous marginal zone lymphoma (PCMZL) represents an indolent subtype of non-Hodgkin lymphoma that is clinically characterized by slowly growing skin tumors with a very low propensity for systemic dissemination. The underlying genetic basis of PCMZL has not been comprehensively elucidated. To gain deeper insight into the molecular pathogenesis of PCMZL, we performed hybridization-based panel sequencing of 38 patients with well-characterized PCMZL. Read More
J Vet Intern Med 2018 Mar 22;32(2):617-632. Epub 2018 Feb 22.
Department of Clinical Studies, University of Pennsylvania, School of Veterinary Medicine, Kennett Square, PA.
Borrelia burgdorferi infection is common in horses living in Lyme endemic areas and the geographic range for exposure is increasing. Morbidity after B. burgdorferi infection in horses is unknown. Read More
Contact Dermatitis 2018 Mar;78(3):230-233
Department of Dermatology, Hospital del Mar. Institut Mar d'Investigacions Médiques, Universitat Autònoma, 08003, Barcelona, Spain.
Abdom Radiol (NY) 2018 Sep;43(9):2288-2294
Shanghai Institute of Medical Imaging, No. 180 Fenglin Road, Xuhui District, Shanghai, 200032, China.
Purpose: To investigate dynamic contrast-enhanced (DCE) MR findings and diffusion-weighted imaging (DWI) characteristics of hepatic pseudolymphoma.
Materials And Methods: The MR data of 20 lesions in 14 patients with histopathologically proven hepatic pseudolymphoma were retrospectively analyzed. All patients underwent dynamic gadopentetate dimeglumine-enhanced MR imaging and DWI. Read More
Medicine (Baltimore) 2017 Nov;96(47):e8656
Rationale: Conjunctival lymphoproliferative lesions constitute a significant diagnostic challenge and it is essential to exclude neoplastic lesions. Histopathological and immunohistochemical tests are very useful in establishing the correct diagnosis. Reactive lymphoid hyperplasia (RLH) is part of a spectrum of lymphocytic infiltrative disorders. Read More
J Cutan Pathol 2018 Apr 18;45(4):296-298. Epub 2018 Feb 18.
Associates in Dermatology, MD PL, Fort Myers, Florida.
Cutaneous intravascular CD30+ pseudolymphoma is an uncommon incidental finding that may mimic intravascular or angiotropic lymphoma. We describe a 78-year-old female with a traumatized regressing keratoacanthoma on her left cheek. A shave biopsy revealed intravascular staining of atypical lymphocytes positive for CD45, CD3 and CD30. Read More
Semin Diagn Pathol 2018 Jul 1;35(4):247-259. Epub 2018 Feb 1.
Regional Medical Laboratory, 4142 South Mingo Road, Tulsa, OK 74146-3632, United States.
Atypical lymphocytic infiltrates of the skin comprise a broad spectrum of entities ranging from benign infiltrates to those that are malignant. Many of these infiltrates are in fact reactive lymphomatoid ones related to drug therapy falling under the general category of drug associated pseudolymphoma. Within this nosologic umbrella are nodular and diffuse infiltrates resembling low grade T and B cell lymphoma consistent with lymphocytoma cutis, drug associated reversible T cell dyscrasias which draw a strong morphologic and phenotypic parallel with mycosis fungoides and the various pre-lymphomatous T cell dyscrasias, and angiocentric CD30 positive infiltrates mirroring lymphomatoid papulosis. Read More
Zhonghua Bing Li Xue Za Zhi 2018 Jan;47(1):39-44
Department of Pathology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
To study the clinicopathological features of primary hepatic extranodal marginal zone lymphoma of mucosa associated lymphoid tissue (MALT lymphoma) and hepatic pseudolymphoma, and to discuss their differential diagnosis, treatment and prognosis. Three primary hepatic MALT lymphomas and two hepatic pseudolymphomas collected from January 2012 to March 2017 in the First Affiliated Hospital of Nanjing Medical University were evaluated by HE and immunohistochemistry(IHC), in-situ hybridization and immunoglobulin (Ig) gene rearrangement detection, and the relevant literature reviewed. In the three MALT lymphomas, tumor cells infiltrated the portal areas with nodular pattern, and invaded the surrounding normal liver with serpiginous configuration and formation of confluent sheets. Read More
J Cutan Pathol 2018 Apr 9;45(4):274-277. Epub 2018 Feb 9.
Departments of Dermatology and Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
Lyme disease classically evolves through clinical manifestations according to the stage of illness. Because many of the systemic symptoms are non-specific, and because serology may yield false negative results, cutaneous findings merit even greater importance to diagnosis. The prototypical skin lesion, erythema migrans (EM), occurs early and is the only independent diagnostic clinical feature according to the guidelines of the Infectious Diseases Society of America. Read More
An Bras Dermatol 2017 ;92(5 Suppl 1):135-137
Department of Pathology. Hospital Universitario Doctor Peset. Valencia. Spain.
Pseudolymphomatous folliculitis is a rare entity included among the cutaneous pseudolymphomas. A 32-year-old man, with an unremarkable medical history, presented with a two-month history of an asymptomatic solitary nodule on his left cheek. Histopathological examination demonstrated a dense nodular and diffuse dermal lymphocytic infiltrate with numerous histiocytes and dendritic cells that surrounded hypertrophic hair follicles. Read More
An Bras Dermatol 2017 ;92(5 Suppl 1):98-100
Department of Medicine of the Faculdade Integral Diferencial (Facid-DeVry) - Teresina (PI), Brazil.
Lymphocytoma cutis, or benign reactive lymphoid hyperplasia, is an inflammatory skin lesion that mimics clinically and histologically malignant lymphoma. Most cases are idiopathic, but they may also be triggered by multiple factors, such as insect bites, tattoos, injections and herpes zoster. Clinically, the lesions are erythematous, soft papules, plaques or nodules, usually located on the upper limbs and face. Read More
Pediatr Dermatol 2018 Jan 4;35(1):e90-e91. Epub 2017 Dec 4.
Division of Dermatology, Department of Pediatrics, School of Medicine, University of Washington and Seattle Children's Hospital, Seattle, WA, USA.
Lyme disease is a common tick-borne infection caused by Borrelia burgdorferi in the United States, where infection is most prevalent in the northeastern and mid-Atlantic states. Although classically associated with erythema migrans, Lyme disease caused by Borrelia species found in Europe may also present with other cutaneous findings. Here we report the case of a girl who was clinically diagnosed with Lyme disease based on her history of recent travel and the appearance of an areolar lymphocytoma; this was confirmed by testing. Read More
BMC Cancer 2017 Dec 4;17(1):815. Epub 2017 Dec 4.
Department of Pathology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Background: PCDH10, one of the non-clustered protocadherins, is identified as a tumor suppressor gene in many tumors. Recently, promoter methylation of PCDH10 was found in diffuse large B-cell lymphoma (DLBCL) but not in normal lymph nodes, suggesting that its epigenetic aberrance is essential to the lymphomagenesis. However, there are few studies on the clinicopathological relevance and prognostic significance of PCDH10 methylation status in DLBCL. Read More
J Cutan Pathol 2018 Mar 27;45(3):226-228. Epub 2017 Dec 27.
Department of Dermatology, Mayo Clinic, Rochester, Minnesota.
Cutaneous reactions to red tattoo pigment rarely manifest as pseudolymphomatous reactions. We describe an exceedingly rare case of red tattoo-related T-cell predominant pseudolymphoma microscopically mimicking mycosis fungoides. Careful clinicopathological correlation was required to obtain the correct diagnosis and aid in an effective treatment course. Read More
Virus Res 2018 01 21;244:147-152. Epub 2017 Nov 21.
College of Animal Science, Fujian Agriculture and Forestry University, Fuzhou, 350002, PR China; Fujian Key Laboratory of Traditional Chinese Veterinary Medicine and Animal Health, Fujian Agricultural and Forestry University, Fuzhou, 350002, PR China.
Avian leukosis virus (ALV) induces multiple avian tumors, growth decrease and immune suppression. Previously, a novel natural recombinant ALV isolate FJ15HT0 was proven to be associated with significant body weight decrease, immune suppression and lymphocytoma in infected SPF chickens. In order to uncover the interaction between virus and host, we compared differences in the transcriptomes of the thymuses from the mock chickens and simulated congenitally infected chickens at 5days (d), 13d and 21d of age by RNA-seq analysis of the thymuses. Read More
Mod Pathol 2018 03 17;31(3):378-384. Epub 2017 Nov 17.
Institute for Advanced Biosciences, UGA/Inserm U 1209/CNRS UMR 5309 joint research center, Grenoble, France.
Pathologists typically encounter many disparate exogenous materials in clinical specimens during their routine histopathological examinations, especially within the skin, lymph nodes, and lungs. These foreign substances may be free extracellular deposits or induce several clinical abnormalities or histopathological patterns. However, pathologists almost never investigate or report the chemical nature of exogenous metals in clinical specimens due to a lack of convenient and available technologies. Read More
Acta Derm Venereol 2018 Mar;98(3):310-317
Department of Dermatology, Jena University Hospital Erfurter Straße 35, DE-07743 Jena, Germany.
Cutaneous pseudolymphoma (CPL) is a reactive polyclonal T- or B-cell lymphoproliferative process. CPL may appear as localized or disseminated skin lesions. While most cases of CPL are idiopathic, they may also occur as a response to, for example, contact dermatitis, arthropod reactions, and bacterial infections. Read More
Cornea 2018 Feb;37(2):255-257
Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, Philadelphia, PA.
Purpose: To describe a case of reactive lymphoid hyperplasia (RLH) of the conjunctiva responding to cyclosporine immunosuppressant monotherapy.
Methods: A 66-year-old man with a 2-year history of biopsy-proven bilateral RLH presented for dry eye evaluation with chief complaints of burning, stinging, and irritation in both eyes. After slit-lamp examination and positive findings of matrix metalloproteinase 9 in the patient's tear film, he was diagnosed with meibomian gland dysfunction and tear-insufficiency dry eye disease. Read More
Hum Pathol 2018 01 28;71:100-108. Epub 2017 Oct 28.
Department of Pathology and INSERM U955 team 9, AP-HP, Henri-Mondor Hospital, 94220 Créteil, France. Electronic address:
Eruption of lymphocyte recovery (ELR) may occur during bone marrow aplasia after chemotherapies. We reviewed the clinical and pathologic features of 12 patients (male-female ratio, 7:5; median age, 61 years) with an atypical ELR histologically mimicking a primary cutaneous T-cell lymphoma such as Sézary syndrome or CD30+ T-cell lymphoproliferative disorder. All the patients displayed an erythematous maculopapular eruption on the trunk and the limbs associated with fever. Read More
Oral Maxillofac Surg 2017 Dec 25;21(4):475-481. Epub 2017 Oct 25.
Department of Pathology and Parasitology, Institute of Biomedical Sciences, Federal University of Alfenas, Rua Gabriel Monteiro da Silva, 700, Alfenas, MG, 37130-001, Brazil.
Follicular lymphoid hyperplasia is a very rare though benign reactive process of an unknown pathogenesis that may resemble a follicular lymphoma, clinically and histologically. Oral reactive follicular hyperplasia (RFH) has been described on the hard or soft palate and at the base of the tongue. We describe here the first case of RFH presenting as an aggressive tumor on the right posterior side of the maxilla in a 24-year-old male patient. Read More
Intern Med 2018 Jan 16;57(2):223-230. Epub 2017 Oct 16.
Department of Gastroenterological, Faculty of Medicine, Fukuoka University, Japan.
A 49-year-old woman who was asymptomatic was found to have a small liver tumor on abdominal ultrasonography (US) at her annual health checkup. US revealed a hypoechoic, solid, mass measuring 17-mm in size in segment 6. The tumor markers associated with liver malignancy were negative. Read More