Search our Database of Scientific Publications and Authors

I’m looking for a

    13522 results match your criteria Lymphedema

    1 OF 271

    Morbidity and Outcomes Following Axillary Lymphadenectomy for Melanoma: Weighing the Risk of Surgery in the Era of MSLT-II.
    Ann Surg Oncol 2017 Nov 20. Epub 2017 Nov 20.
    Division of Surgical Oncology, Department of Surgery, Winship Cancer Institute, Emory University, Atlanta, GA, USA.
    Background: Limited data exist characterizing complications after axillary lymphadenectomy for melanoma. With high rates of complications reported after dissection for breast cancer and data suggesting that completion lymphadenectomy may have limited therapeutic benefit, this study characterized morbidity to facilitate clinical decision-making.

    Methods: Using a broad definition for complications, patients who underwent axillary dissection for melanoma at a single center (from 2003 to 2015) were assessed through retrospective chart review. Read More

    A journey through liposuction and liposculture: Review.
    Ann Med Surg (Lond) 2017 Dec 6;24:53-60. Epub 2017 Nov 6.
    Department of Medicine and Surgery, Plastic Surgery Section, University of Parma, Cutaneous, Mini-invasive, Regenerative and Plastic Surgery Unit, Parma University Hospital, Parma, Italy.
    Introduction: Nowadays, liposuction is the most frequently performed aesthetic surgery procedure in Western Countries. This technique has had rapid development since the 1970s, when it was experimented for the first time by A. and G. Read More

    [TB/HIV co-infection associated with Kaposi's sarcoma under opioid substitution treatment using methadone: about a case].
    Pan Afr Med J 2017 15;28:43. Epub 2017 Sep 15.
    Service des Maladies Infectieuses et Tropicales, Centre Hospitalier National Universitaire de Fann Dakar /Université Cheikh Anta Diop de Dakar, BP 5035 Dakar, Sénégal.
    Late diagnosis of HIV infection can be fatal because it favors the appearance of opportunistic infections whose management requires the use of several molecules which can cause drug interactions. We report the case of a 45-year old female patient under heroin substitution treatment, using methadone and with HIV1 under antiretroviral treatment. This patient had nonspecific pulmonary appearance associated with dry nagging cough and progressive dyspnea evolving in a feverish context. Read More

    Air Travel and Postoperative Lymphedema-A Systematic Review.
    Clin Breast Cancer 2017 Oct 19. Epub 2017 Oct 19.
    Department of Surgery, Queen Mary Hospital, The University of Hong Kong, Hong Kong, Hong Kong Special Administrative Region. Electronic address:
    Lymphedema is not uncommon after axillary dissection for breast cancer. Improved survival of patients with breast cancer from advances in adjuvant therapy has resulted in increased awareness of the quality of life for long-term survivors. Air travel has been postulated as 1 of the risk factors of lymphedema exacerbation. Read More

    Estimating the number of cases of podoconiosis in Ethiopia using geostatistical methods.
    Wellcome Open Res 2017 4;2:78. Epub 2017 Sep 4.
    Wellcome Trust Brighton and Sussex Centre for Global Health Research, Brighton and Sussex Medical School, Brighton, UK.
    Background: In 2011, the World Health Organization recognized podoconiosis as one of the neglected tropical diseases. Nonetheless, the number of people with podoconiosis and the geographical distribution of the disease is poorly understood. Based on a nationwide mapping survey and geostatistical modelling, we predict the prevalence of podoconiosis and estimate the number of cases across Ethiopia. Read More

    Toe web intertrigo in Kaposi's sarcoma patients: a microbiological study in a large cohort of patients.
    Eur J Clin Microbiol Infect Dis 2017 Nov 17. Epub 2017 Nov 17.
    Dermatology Unit, I.R.C.C.S. Foundation Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
    Kaposi 's sarcoma (KS) is a rare multifocal angioproliferative disease associated with human herpes virus 8 (HHV-8) infection, characterized by cutaneous nodules or plaques especially on the lower limbs. Some skin modifications, such as chronic lymphedema, plantar hyperkeratosis and interdigital desquamation, may be associated with consequent impairment of the local immunosurveillance and increased risk of some bacterial or mycotic infections. With the objective of evaluating if bacterial or mycotic infections in KS patients are supported by different microorganisms compared to control patients, we performed an observational retrospective study, comparing positive cultural swabs of interdigital intertrigo of KS patients with positive cultural swabs of interdigital intertrigo of patients admitted to our dermatologic unit during the last 10 years. Read More

    Incidence of lower limb lymphedema after vulvar cancer: A systematic review and meta-analysis.
    Medicine (Baltimore) 2017 Nov;96(46):e8722
    Division of Plastic and Reconstructive Surgery, Peking Union Medical College Hospital, Beijing, China.
    Background: Lower limb lymphedema (LLL) is an important concern for patients with vulvar cancer. Studies of the incidence of vulvar cancer-related lymphedema and its risk factors have substantially increased in the new millennium.

    Objectives: This article is a meta-analysis that aimed to systematically evaluate the incidence of LLL and its risk factors related to vulvar cancer. Read More

    Use of a Novel Portable Three-Dimensional Scanner to Measure Limb Volume and Circumference in Patients with Filarial Lymphedema.
    Am J Trop Med Hyg 2017 Oct 16. Epub 2017 Oct 16.
    Infectious Diseases Division, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.
    The World Health Organization's Global Program to Eliminate Lymphatic Filariasis (LF) has reduced LF transmission worldwide, but millions remain affected by filarial lymphedema. Tools for clinically monitoring lymphedema in developing nations are limited. We tested a novel, portable, infrared three-dimensional (3D) scanner against water displacement (WD) and tape measurement of limb circumference (TMLC) among patients with filarial leg lymphedema in Galle, Sri Lanka. Read More

    Immunohistochemical and Fluorescence In Situ Hybridization Analysis of MYC in a Series of 17 Cutaneous Angiosarcomas: A Single-Center Study.
    Am J Dermatopathol 2017 Nov 7. Epub 2017 Nov 7.
    Departments of *Dermatology, †Molecular Biology, ‡Oncology, and §Pathology, Instituto Valenciano de Oncología, Valencia, Spain.
    Cutaneous angiosarcoma (AS) is an uncommon aggressive sarcoma whose incidence is rising because of the increasing use of radiation therapy, especially in breast cancer. The few studies on the relevance of prognostic factors, such as MYC status in cutaneous AS, have reported inconclusive findings, with some authors reporting MYC amplification only in postirradiation and lymphedema-associated AS and others reporting evidence of MYC amplification in idiopathic AS. We analyzed 17 cases of cutaneous AS (6 idiopathic AS, 10 postirradiation AS, and 1 lymphedema-associated AS) treated at our institute between 2000 and 2015. Read More

    Lymphedema: Diagnostic workup and management.
    J Am Acad Dermatol 2017 Dec;77(6):995-1006
    Department of Dermatology, Boston University School of Medicine, Boston, Massachusetts.
    Lymphedema is a localized form of tissue swelling resulting from excessive retention of lymphatic fluid in the interstitial compartment. It is caused by impaired lymphatic drainage. Lymphedema is a chronic progressive disease with serious physical and psychosocial implications. Read More

    Lymphedema: Pathophysiology and clinical manifestations.
    J Am Acad Dermatol 2017 Dec;77(6):1009-1020
    Department of Dermatology, Boston University School of Medicine, Boston, Massachusetts.
    Lymphedema is a localized form of tissue swelling resulting from excessive retention of lymphatic fluid in the interstitial compartment and caused by impaired lymphatic drainage. Lymphedema is classified as primary or secondary. Primary lymphedema is caused by developmental lymphatic vascular anomalies. Read More

    Surgical Intervention for Lymphedema.
    Surg Oncol Clin N Am 2018 Jan;27(1):195-215
    Department of Surgery, The University of North Carolina at Chapel Hill, Campus Box 7213, 1150 POB, 170 Manning Drive, Chapel Hill, NC 27599-7123, USA.
    Lymphedema is a chronic, progressive disease with no curative treatment. Breast cancer therapy is the most common cause of secondary lymphedema in the developed world. Treatment includes nonsurgical and surgical strategies. Read More

    Guidelines for teaching yoga to women with breast cancer-related lymphoedema: an evidence-based approach.
    Int J Yoga Therap 2017 Nov;27(1):95-112
    4. Department of Surgery, Flinders University, Adelaide, Australia.
    Breast cancer-related lymphoedema (BCRL) is a chronic condition that requires lifelong management to prevent the condition worsening and to reduce the threat of infection. Women are affected in all domains of their life. As a holistic practice, yoga may be of benefit by reducing both the physical and psychosocial effects of lymphoedema. Read More

    Usability of advanced pneumatic compression to treat cancer-related head and neck lymphedema: A feasibility study.
    Head Neck 2017 Nov 13. Epub 2017 Nov 13.
    Department of Otolaryngology, Sound Health Services, St. Louis, Missouri.
    Background: This functional usability study assessed ease of use, fit, comfort, and potential clinical benefits of advanced pneumatic compression treatment of cancer-related head and neck lymphedema.

    Methods: Patient-reported comfort and other treatment aspects were evaluated and multiple face and neck measurements were obtained on 44 patients with head and neck lymphedema before and after 1 treatment session to assess usability and treatment-related lymphedema changes.

    Results: A majority of the patients (82%) reported the treatment was comfortable; most patients (61%) reported feeling better after treatment, and 93% reported that they would be likely to use this therapy at home. Read More

    [Nursing role and TPE in patients with lymphoedema of the limbs].
    Rev Infirm 2017 Nov;66(235):41-43
    Centre national de référence des maladies vasculaires rares (lymphœdèmes primaires), Unité de lymphologie, Hôpital Cognacq-Jay, 15, rue Eugène-Millon, 75015 Paris, France.
    Lymphoedema, primary and secondary after cancer treatment, is a chronic condition which has a significant impact on patients' quality of life. Therapeutic education plays an important role in the initial care and in the follow-up of these conditions. Read More

    Changes in volume and incidence of lymphedema during and after treatment with docetaxel, doxorubicin, and cyclophosphamide (TAC) in patients with breast cancer.
    Support Care Cancer 2017 Nov 10. Epub 2017 Nov 10.
    Department of Medical Oncology, Radboud University Medical Center, Nijmegen, The Netherlands.
    Purposes: The purposes of this study were to investigate the incidence of lymphedema in patients with breast cancer during and after adjuvant treatment with docetaxel, doxorubicin, and cyclophosphamide (TAC), to identify predictors for development of lymphedema, and to describe consequences in daily life in relation to lymphedema.

    Methods: This is a prospective study with measurements before chemotherapy (T0), during chemotherapy before cycle 2 (T1), cycle 4 (T2), and 1 month after completion of treatment (T3). Volume change was monitored using tape measurements. Read More

    Evaluation of the economic impact of a national lymphoedema service in Wales.
    Br J Nurs 2017 Nov;26(20):1093-1100
    National Clinical Lead for Lymphoedema in Wales, Lymphoedema Network Wales, Cimla Social Care Centre, Neath, West Glamorgan.
    Lymphoedema Network Wales has focused on maximising the impact of its service through the effective use of available resources to ensure high-quality and consistent care for people with lymphoedema across Wales. The aim of this evaluation was to estimate the economic impact of a national lymphoedema service on the NHS Wales budget. Work was undertaken to determine the care pathway within Lymphoedema Network Wales and develop a hypothetical 'world without' the service as a comparator. Read More

    Single nucleotide polymorphisms in the angiogenic and lymphangiogenic pathways are associated with lymphedema caused by Wuchereria bancrofti.
    Hum Genomics 2017 Nov 9;11(1):26. Epub 2017 Nov 9.
    Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Germany.
    Background: Lymphedema (LE) is a chronic clinical manifestation of filarial nematode infections characterized by lymphatic dysfunction and subsequent accumulation of protein-rich fluid in the interstitial space-lymphatic filariasis. A number of studies have identified single nucleotide polymorphisms (SNPs) associated with primary and secondary LE. To assess SNPs associated with LE caused by lymphatic filariasis, a cross-sectional study of unrelated Ghanaian volunteers was designed to genotype SNPs in 285 LE patients as cases and 682 infected patients without pathology as controls. Read More

    A review of squamous cell vulvar cancers in Waikato region, New Zealand.
    N Z Med J 2017 Nov 10;130(1465):19-28. Epub 2017 Nov 10.
    Medical Oncologist, Lomas Building, Waikato Hospital, Pembroke Street, Hamilton.
    Background: Squamous cell vulvar cancers (SCVC) are rare. Although management guidelines have recently been published, New Zealand studies presenting "real world" outcomes are limited.

    Methods: Retrospective single-centre review of SCVC diagnosed between 1 January 2000 and 31 August 2015. Read More

    [What physiotherapeutic method for the treatment of post-mastectomy lymphedema is the most effective?]
    Vopr Kurortol Fizioter Lech Fiz Kult 2017 ;94(4):59-66
    Moscow state autonomous healthcare facility 'Moscow Scientific and Practical Centre for Medical Rehabilitation, Restorative and Sports Medicine', Zemlyanoy val, 53, Moscow, Russia, 105120.
    We have undertaken the search for the publications of interest in the following databases: Scopus, Web of Science, MedLine, The Cochrane Library, CyberLeninka, and Russian science citation index. In addition, we evaluated the effectiveness of the physical agents and procedures having different mechanisms of action of the known factors responsible for the development of post-mastectomy lymphedema. Such agents and procedures include self-massage, manual lymphatic drainage, therapeutic physical exercises, compression bandaging, wearing elastic compression garments, Kinesio Tex taping, pneumatic compression, ultrasonic, electrostatic, extracorporeal shock wave therapy, electrical muscle stimulation, microcurrent and low-intensity laser therapy. Read More

    Managing chronic oedema and wet legs in the community: a service evaluation.
    Nurs Stand 2017 Nov;32(11):39-50
    Lymphoedema Network Wales, Cimla Hospital, West Glamorgan, Wales.
    Patients with chronic oedema and 'wet legs' are frequently seen in the community setting, with research indicating that more than half of community nurses' caseloads are patients with chronic oedema. However, a lack of nurse education and standardised care pathways for this condition has been identified. In June 2016, the Welsh Government supported the development of the On the Ground Education Project (OGEP), which aimed to raise community nurses' awareness and recognition of chronic oedema and wet legs, to improve the management of these conditions, and to support the efficient use of community nurses' time and resources. Read More

    Post-irradiation morphoea of the breast: a case report and review of the literature.
    Histopathology 2017 Aug 14. Epub 2017 Aug 14.
    Breast Cancer Research Program, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA.
    We describe a 44-year-old female with triple-negative breast cancer who developed skin erythaema, sclerosis and contracture of her entire right breast 15 months after completion of post-lumpectomy chemotherapy and radiotherapy, consistent with post-irradiation morphoea (PIM). PIM is a rare complication of breast irradiation that impairs a patient's quality of life. PIM is located usually at the radiation port or in the surrounding tissue. Read More

    [Use of indocyanine green angiography in oncological and reconstructive breast surgery].
    Ann Chir Plast Esthet 2017 Oct 26. Epub 2017 Oct 26.
    Department of Plastic Surgery, Gustave-Roussy, 114, rue Edouard-Vaillant, 94800 Villejuif, France.
    The Indocyanine green (ICG) is a soluble dye that is eliminated by the liver and excreted in bile. When illuminated by an near-infrared light, the ICG emits fluorescence in the near-infrared spectrum, which can be captured by a near-infrared camera-handled device. In case of intravenous injection, ICG may be used as a marker of skin perfusion. Read More

    Factors associated with professional healthcare advice seeking in women at risk for developing breast cancer-related lymphedema.
    Patient Educ Couns 2017 Oct 18. Epub 2017 Oct 18.
    Vanderbilt University School of Nursing, Nashville, USA.
    Objectives: Approximately 6-20% of breast cancer patients undergoing lymph node surgery will develop lymphedema. At-risk individuals are encouraged to seek professional healthcare advice if symptoms arise. This study aimed to identify cognitive and affective factors associated with professional healthcare advice (PHCA) seeking behavior in women with heightened lymphedema risk. Read More

    Effect of pneumatic compression therapy on lymph movement in lymphedema-affected extremities, as assessed by near-infrared fluorescence lymphatic imaging.
    J Innov Opt Health Sci 2017 Mar 28;10(2). Epub 2016 Sep 28.
    Center for Molecular Imaging, The Brown Institute for Molecular Medicine, UTHealth, Houston, Texas.
    Previous studies have shown cost effectiveness and quality-of-life benefit of pneumatic compression therapy (PCT) for lymphedema. Insurers, such as the Centers for Medicare/Medicaid (CMS), however, desire visual proof that PCT moves lymph. Near-infrared fluorescence lymphatic imaging (NIRFLI) was used to visualize lymphatic anatomy and function in four subjects with primary and cancer treatment-related lymphedema (LE) of the lower extremities before, during, and after pneumatic compression therapy (PCT). Read More

    Multi-site lymphatic venous anastomosis using echography to detect suitable subcutaneous vein in severe lymphedema patients.
    J Plast Reconstr Aesthet Surg 2017 Oct 17. Epub 2017 Oct 17.
    Department of Plastic and Reconstructive Surgery, the University of Tokyo, Tokyo, Japan.
    Background: The method of lymphatic venous anastomosis (LVA), including its indications or preoperative examinations, has not been established. The purpose of this study is to reveal the possible application of preoperative echography in surgical LVA outcome.

    Methods: We performed a retrospective case-control study on patients with lower limb lymphedema who underwent LVA between August 15, 2013 and August 15, 2014. Read More

    Investigating the Lymphatic System by Dual-Color Elemental Mass Spectrometry Imaging.
    Contrast Media Mol Imaging 2017 29;2017:4035721. Epub 2017 Jan 29.
    Department of General and Visceral Surgery, University Hospital Muenster, 48149 Muenster, Germany.
    Secondary lymphedema accompanied with strong restrictions in quality of life is still major side effects in cancer therapy. Therefore, dedicated diagnostic tools and further investigation of the lymphatic system are crucial to improve lymphedema therapy. In this pilot study, a method for quantitative analysis of the lymphatic system in a rat model by laser ablation (LA) with inductively coupled plasma mass spectrometry imaging (ICP-MSI) is presented. Read More

    Prevalence and Consequences of Axillary Lymph Node Dissection in the Era of Sentinel Lymph Node Biopsy for Breast Cancer.
    Med Care 2017 Oct 30. Epub 2017 Oct 30.
    *Department of Surgery ‡Division of Biostatistics §Department of Medicine †Center for Patient Care and Outcomes Research, Medical College of Wisconsin, Milwaukee, WI.
    Background: Despite clear guidelines for its use and wide adoption, no population-based study has examined the extent to which patients with early stage breast cancer are benefiting from sentinel lymph node biopsy (SLNB) by being spared a potentially avoidable axillary lymph node dissection (ALND) and its associated morbidity.

    Objective: Examine variation in type of axillary surgery performed by surgeon volume; investigate the extent and consequences of potentially avoidable ALND.

    Research Design/subjects: Observational study of older women with pathologically node-negative stage I-II invasive breast cancer who underwent surgery in a SEER state in 2008-2009. Read More

    Strategies for Avoiding Benzopyrone Hepatotoxicity in Lymphedema Management-The Role of Pharmacogenetics, Metabolic Enzyme Gene Identification, and Patient Selection.
    Lymphat Res Biol 2017 Oct 31. Epub 2017 Oct 31.
    2 Lymphoedema Clinical Research Unit , Department of Surgery, Flinders Medical Centre, South Australia, Australia .
    Introduction: Benzopyrones are plant-derived chemicals which have an evidenced degree of clinical efficacy in lymphedema management indicated in past trials. Unfortunately, in some of these cases idiosyncratic hepatotoxicity have been documented in a minority of patients. This review aims to tackle the problem of benzopyrone (particularly coumarin) toxicity by considering their metabolic pathways and identifying relevant alleles needed to take a targeted pharmacogenetic approach in its future use. Read More

    Local Echo-Free Space in a Limb with Lymphedema Represents Extracellular Fluid in the Entire Limb.
    Lymphat Res Biol 2017 Oct 31. Epub 2017 Oct 31.
    Division of Vascular Surgery, Department of Surgery and Clinical Science, Yamaguchi University Graduate School of Medicine , Yamaguchi, Japan .
    Background: We previously reported that local subcutaneous echo-free space (SEFS) in the leg was stirringly correlated with extracellular fluid (ECF) status in the same part of the leg when assessed using bioelectrical impedance analysis (BIA). In this study, we examined whether local SEFS represents the ECF status in the entire limb.

    Methods And Results: In 51 legs and 40 arms with lymphedema (LE), subcutaneous tissue ultrasonography was performed to determine SEFS severity (range, 0-2). Read More

    Donor-Site Lymphedema Following Lymph Node Transfer for Breast Cancer-Related Lymphedema: A Systematic Review of the Literature.
    Lymphat Res Biol 2017 Oct 31. Epub 2017 Oct 31.
    Department of Plastic Surgery, Faculty of Health Sciences, School of Medicine, "Papageorgiou" Hospital, Aristotle University of Thessaloniki , Thessaloniki, Greece .
    Abstracts Background: Among current surgical options used for treating breast cancer-related lymphedema (BCRL), autologous lymph node transfer (ALNT) is shown to provide favorable results. However, postoperative donor-site lymphedema (DSL), following the lymphatic flap harvesting from the groin area, has already been reported. Our aim is to summarize the recent literature for evidence of DSL following an ALNT for BCRL. Read More

    Adapting Lymphedema Treatment in Patients with a Mental Disability.
    Case Rep Psychiatry 2017 11;2017:4958127. Epub 2017 Sep 11.
    Research Group of Clínica Godoy, São José do Rio Preto, SP, Brazil.
    Background And Purpose: Mental disability is often characterized by significant limitations in adaptive skills. When this condition is associated with lymphedema, treatment requires greater commitment of the care team. The objective of this study is to report the treatment of lymphedema using only one therapeutic technique, a low-stretch grosgrain stocking. Read More

    Initiating Exercise Interventions to Promote Wellness in Cancer Patients and Survivors.
    Oncology (Williston Park) 2017 10;31(10):711-7
    Exercise is associated with significant reductions in the recurrence and mortality rates of several common cancers. Cancer survivors who exercise can potentially benefit from reduced levels of fatigue, and improved quality of life, physical function, and body composition (ie, healthier ratios of lean body mass to fat mass). The amount of activity required to achieve protective effects is moderate (eg, walking 30 minutes per day at 2. Read More

    RAMP1 signaling improves lymphedema and promotes lymphangiogenesis in mice.
    J Surg Res 2017 Nov 23;219:50-60. Epub 2017 Jun 23.
    Department of Pharmacology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan. Electronic address:
    Background: Secondary lymphedema commonly arises as a complication of cancer surgery and radiation treatment; however, the underlying mechanisms are poorly understood. Receptor activity-modifying protein 1 (RAMP1) forms a complex with calcitonin receptor-like receptor to generate the receptor for calcitonin gene-related peptide. The present study examined whether RAMP1 plays a role in increased lymphangiogenesis during secondary lymphedema. Read More

    Bipolar Radiofrequency Ablation (Coblation) of External Auditory Canal Lymphatic Malformation and Other Soft Stenoses.
    Ann Otol Rhinol Laryngol 2017 Dec 27;126(12):835-838. Epub 2017 Oct 27.
    1 The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
    Introduction: Soft tissue occlusion of the external auditory canal (EAC) can cause intense pruritis, recurrent foul smelling otorrhea, recurrent otitis externa, and conductive hearing loss. Occlusion of the EAC can be challenging to treat as the area is prone to circumferential scarring.

    Methods: We describe the novel use of serial bipolar radiofrequency ablation (coblation) to treat 3 children with complete EAC occlusion from congenital and acquired conditions including lymphedema (1), microcystic lymphatic malformation (1), and venolymphatic malformation (1). Read More

    Human Immunodeficiency Virus-Negative-Associated Lymphangioma-like Kaposi's Sarcoma with Variable Clinical PresentationsA Case Report.
    J Am Podiatr Med Assoc 2017 Sep;107(5):461-466
    Lymphangioma-like Kaposi's sarcoma (LLKS) is a rare histologic variant of KS. Kaposi's sarcoma is also known as human herpesvirus type 8. The clinical presentation of the LLKS lesion is highly unusual and similar to that of classic KS but with multinodular vascular tumors and lymphedema. Read More

    Local anesthetic delivery via surgical drain provides improved pain control versus direct skin infiltration following axillary node dissection for breast cancer.
    Breast Cancer 2017 Oct 26. Epub 2017 Oct 26.
    Anesthetics and Surgical Department, Medway Maritime Foundation Trust, Gillingham, Kent, UK.
    Background: Axillary node dissection has a central role in the surgical management of breast cancer; however, it is associated with a significant risk of lymphoedema and chronic pain. Peri-operative administration of local anesthesia reduces acute and persistent post-surgical pain, but there is currently no consensus on the optimal method of local anesthetic delivery.

    Methods: Patients undergoing axillary dissection for breast cancer were randomly assigned to receive a one-off dose of levobupivacaine 0. Read More

    Promoter-level transcriptome in primary lesions of endometrial cancer identified biomarkers associated with lymph node metastasis.
    Sci Rep 2017 Oct 26;7(1):14160. Epub 2017 Oct 26.
    Division of Genomic Technologies, RIKEN Center for Life Science Technologies, Yokohama, Japan.
    For endometrial cancer patients, lymphadenectomy is recommended to exclude rarely metastasized cancer cells. This procedure is performed even in patients with low risk of recurrence despite the risk of complications such as lymphedema. A method to accurately identify cases with no lymph node metastases (LN-) before lymphadenectomy is therefore highly required. Read More

    Lymphatic Territories (Lymphosomes) in the Rat: An Anatomical Study for Future Lymphatic Research.
    Plast Reconstr Surg 2017 Nov;140(5):945-951
    Sydney, New South Wales, Australia; Houston, Texas; and Zurich, Switzerland From Australian Lymphoedema Education, Research and Treatment, Faculty of Medicine and Health Sciences, Macquarie University; the Department of Plastic Surgery, University of Texas M. D. Anderson Cancer Center; and the Department of Plastic Surgery and Hand Surgery, University Hospital Zurich.
    Background: Understanding the precise anatomy in experimental animals is crucial for correct design of research projects. Rats are commonly used for scientific research in plastic surgery because of their availability in academic institutions, moderate cost, and sizable vessels for microsurgical procedures. In past publications about rat anatomy, lymphatic mapping has been limited and incomplete. Read More

    Yellow Nail Syndrome Presenting With a Pericardial Effusion: A Case Report and Review of the Literature.
    J Cutan Med Surg 2017 Oct 1:1203475417738970. Epub 2017 Oct 1.
    2 Professor of Medicine, University of Calgary, Alberta, Canada.
    Yellow nail syndrome (YNS) is a constellation of clinical findings including at least 2 of the 3 features of thickened yellow nails, respiratory tract involvement, and lymphedema. We report the case of a middle-aged man presenting with dystrophic, thickened yellow nails; an idiopathic pericardial effusion in the absence of pleural effusion(s); and unilateral apical bronchiectasis found on computed tomography of the chest. This represents a unique presentation of YNS as the first report of a patient with YNS and a pericardial effusion in the absence of pleural effusions and lymphedema and is the 11th case report of YNS with pericardial effusion. Read More

    Leiomyosarcoma presenting as 'idiopathic' unilateral lower limb lymphoedema.
    BMJ Case Rep 2017 Oct 23;2017. Epub 2017 Oct 23.
    Trauma and Orthopaedics Department, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK.
    A 74-year-old woman presented with an 8-year history of unilateral swelling of her right lower limb, which was thought to be 'idiopathic' lymphoedema until she noticed a painless swelling in her right groin. Physical examination showed a painless, non-pulsatile, deep-seated mass in her right proximal thigh with significant lymphoedema distally. MRI scan showed a large mass at her right inguinal region, involving the common femoral vein. Read More

    Translating Research into Reality: Elimination of Lymphatic Filariasis from Haiti.
    Am J Trop Med Hyg 2017 Oct;97(4_Suppl):71-75
    University of Notre Dame, Notre Dame, Indiana.
    Research provides the essential foundation of disease elimination programs, including the global program to eliminate lymphatic filariasis (GPELF). The development and validation of new diagnostic tools and intervention strategies, critical steps in the evolution of GPELF, required a global effort. Lymphatic filariasis research in Haiti involved many partners and was directly linked to the development of the national elimination program and to the success achieved to date. Read More

    The Effect of Yoga on Arm Volume, Strength, and Range of Motion in Women at Risk for Breast Cancer-Related Lymphedema.
    J Altern Complement Med 2017 Oct 24. Epub 2017 Oct 24.
    10 Department of Physical Therapy and Rehabilitation Science, University of California San Francisco , San Francisco, CA.
    Objectives: To assess the feasibility, safety, and initial estimates of efficacy of a yoga program in postoperative care for women at high risk for breast cancer-related lymphedema (BCRL).

    Design: Single-group pretest-post-test design.

    Settings/location: Patients were recruited from the University of California, San Francisco Carol Franc Buck Breast Care Center. Read More

    Reducing chronic breast cancer-related lymphedema utilizing a program of prospective surveillance with bioimpedance spectroscopy.
    Breast J 2017 Oct 24. Epub 2017 Oct 24.
    Nashville Breast Center, Nashville, TN, USA.
    This single-institution experience evaluated the use of bioimpedance spectroscopy to facilitate early detection and treatment of breast cancer-related lymphedema (BCRL) in a cohort of 596 patients (79.6% high risk). Seventy-three patients (12%) developed an elevated L-Dex score with axillary lymph node dissection (P < . Read More

    Integrated geometric and mechanical analysis of an image-based lymphatic valve.
    J Biomech 2017 Nov 7;64:172-179. Epub 2017 Oct 7.
    ZCCE, College of Engineering, Swansea University, United Kingdom. Electronic address:
    Lymphatic valves facilitate the lymphatic system's role in maintaining fluid homeostasis. Malformed valves are found in several forms of primary lymphœdema, resulting in incurable swelling of the tissues and immune dysfunction. Their experimental study is complicated by their small size and operation in low pressure and low Reynolds number environments. Read More

    Lymphatic pathology in asymptomatic and symptomatic children with Wuchereria bancrofti infection in children from Odisha, India and its reversal with DEC and albendazole treatment.
    PLoS Negl Trop Dis 2017 Oct 23;11(10):e0005631. Epub 2017 Oct 23.
    Tropical Projects, Hitchin, United Kingdom.
    Background: Once interruption of transmission of lymphatic filariasis is achieved, morbidity prevention and management becomes more important. A study in Brugia malayi filariasis from India has shown sub-clinical lymphatic pathology with potential reversibility. We studied a Wuchereria bancrofti infected population, the major contributor to LF globally. Read More

    1 OF 271