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    1 OF 131

    Synovial sarcoma complicating Maffucci syndrome.
    Indian J Dermatol Venereol Leprol 2018 Apr 17. Epub 2018 Apr 17.
    Department of Dermatology, Farhat Hached University Hospital, Sousse, Tunisia.
    Maffucci syndrome is a rare nonhereditary disorder comprising of lymphovascular malformations and multiple enchondromas, which may be associated with several internal malignancies. This report describes a new association of Maffucci syndrome with pedal synovial sarcoma. Our case is also remarkable as lymphangioma circumscriptum is the sole lymphovascular component, which has been rarely reported. Read More

    Experience with OK-432 in lymphatic vascular malformations in a hospital from northern Mexico.
    Bol Med Hosp Infant Mex 2018 ;75(2):89-93
    Escuela de Medicina, Tecnológico de Monterrey, Monterrey. Nuevo León, México.
    Background: Lymphatic vascular malformations (LVM) or formerly called lymphangiomas are congenital malformations present in about 1 out of 6000 to -16000 births. The most relevant classification system for lymphangioma management is based on the size of the cysts. Spontaneous resolution is uncommon; thus, expectant management is not recommended. Read More

    Percutaneous full endoscopic treatment of cystic lymphangioma of cauda equina: a case report.
    Br J Neurosurg 2018 Apr 16:1-3. Epub 2018 Apr 16.
    c Department of Neurosurgery , Nanoori Incheon Hospital , Incheon , South Korea.
    Intraspinal epidural lymphangioma of cauda equina are extremely rare, only three cases have been reported in the past. We report a 63-year-old female with lymphangioma at S1-S2 level which was resected under epidural anesthesia using a percutaneous full endoscope with no evidence of recurrence at 19 months follow-up. Read More

    Isolated splenic lymphangioma presenting as a huge mass causing anemia and abdominal distension in an adult patient: a case report.
    J Med Case Rep 2018 Apr 16;12(1):97. Epub 2018 Apr 16.
    Department of Pathology, Hassan II University Hospital, Fez, Morocco.
    Background: Lymphangiomas are uncommon benign lesions of lymphatic vessels very rarely affecting the spleen. Isolated involvement of the spleen in adult patients is rarely reported.

    Case Presentation: We report a case of a 40-year-old Arabic woman who presented with a 25-cm abdominal mass, fatigue, and anemia evolving for 6 months. Read More

    Robotic resection of benign nonadrenal retroperitoneal tumors: A consecutive case series.
    Int J Surg 2018 Apr 12. Epub 2018 Apr 12.
    Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong Special Administrative Region. Electronic address:
    Background: The deep location, narrow operative space and proximity to major vessels make minimally invasive resection of nonadrenal retroperitoneal tumors (NTRs) challenging and rarely reported. This study aimed to evaluate the safety and feasibility of robotic resection of benign nonadrenal retroperitoneal tumors.

    Methods: The demographics and perioperative outcomes of a consecutive series of patients who underwent robotic NTR resection between January 1, 2015, and August 30, 2017, were analyzed. Read More

    A case of extensive acquired progressive lymphangioma.
    Pediatr Dermatol 2018 Apr 6. Epub 2018 Apr 6.
    Department of Dermatology, Mayo Clinic, Rochester, MN, USA.
    Acquired progressive lymphangioma (benign lymphangioendothelioma) is a rare lymphatic anomaly of unclear pathogenesis. Excision is generally advised for local disease, although other therapies have been tried. This report describes a unique case of extensive acquired progressive lymphangioma involving the abdomen, genitalia, and lower extremity of a 1-year-old boy. Read More

    Unilateral Straight Hair-A Symptom of Acquired Horner's Syndrome in a Neonate.
    European J Pediatr Surg Rep 2018 Jan 6;6(1):e32-e36. Epub 2018 Apr 6.
    Department of Pediatric Surgery, University Children's Hospital Basel, Basel, Switzerland.
    A multicystic tumor of the right neck was detected in a girl at 29 weeks of gestation by fetal ultrasound and magnetic resonance imaging (MRI). The baby was delivered by cesarean section at week 37 of gestation. The newborn adapted well, with minimal compromise of breathing and drinking. Read More

    Interpreting body MRI cases: classic findings in abdominal MRI.
    Abdom Radiol (NY) 2018 Mar 28. Epub 2018 Mar 28.
    Radiology, Thomas Jefferson University Hospital, 132 South 10th Street, Suite 1087, Main Building, Philadelphia, PA, 19107, USA.
    Few things in radiology are "pathognomonic" in their appearance or presentation. However, having an awareness of those findings which are specific to a certain entity is important when interpreting imaging studies. These classic findings can be identified with many imaging modalities, but no modality provides as many recognizable observations as an MRI. Read More

    Orbital Lymphaticovenous Malformation with Intradural Extension: A Rare Case.
    World Neurosurg 2018 Mar 16. Epub 2018 Mar 16.
    Department of Clinical Neurosciences, University of Calgary, Foothills Medical Centre, Calgary, Alberta, Canada. Electronic address:
    Background: Orbital lymphaticovenous malformations (LVM) are congenital vascular lesions that are typically infiltrative in nature. There have been reports of orbital LVMs extending intracranially through orbital fissures, but there have been no reports of intradural extension.

    Case Description: We report the first case of orbital LVM extending intradurally through a bony defect in the medial orbital roof. Read More

    Small bowel lymphangioma causing ileo-ileal intussusception in adults.
    Int J Surg Case Rep 2017 21;41:469-472. Epub 2017 Nov 21.
    Department of Surgery, Montefiore New Rochelle Hospital, New York, USA.
    Introduction: Lymphangioma is a rare benign tumor found in gastrointestinal tract. Most lymphangiomas can occur at any age and but mostly are found in children and infants. They are mainly due to malformation of the lymphatic system. Read More

    [Unusual macrocystic lymphatic malformation in an adult patient].
    Pan Afr Med J 2017 10;28:128. Epub 2017 Oct 10.
    Service de Dermatologie-Vénéréologie, CHU Ibn Rochd, Université Hassan II, Casablanca, Maroc.
    Macrocystic lymphatic malformations (MLMs) constitute a circumscribed variation in deep lymphangiomas. They are characterized by a rare occurrence in adults, by their rapid expansion and by their frequent occurrence at the level of the cervicofacial region (75%) and axillary region (20%). They rarely occur in lower limbs. Read More

    Oral lymphangiomas - clinical and histopathological relations: An immunohistochemically analyzed case series of varied clinical presentations.
    J Oral Maxillofac Pathol 2018 Jan;22(Suppl 1):S108-S111
    Department of Oral Pathology and Microbiology, Sarjug Dental College, Darbhanga, Bihar, India.
    Lymphangiomas are benign malformations that represent hamartoma of malformed lymphatics and are composed of cystically dilated lymphatic channels which do not communicate or drain into other lymphatic channels or veins leading to accumulation of lymph. They are congenital malformations with rare occurrence in oral cavity within which tongue dorsum is the most affected site. Venous malformations are often difficult to differentiate from lymphatic malformations leading to the development of several lymphatic markers like D2-40 which seems to be useful for distinguishing vascular from lymphatic vessels. Read More

    Congenital lymphangioma circumscriptum of vulva presenting as multiple giant mass lesions: a case report and literature review.
    J Obstet Gynaecol Res 2018 Feb 27. Epub 2018 Feb 27.
    Department of Pathology, Cancer Institute, Imam Khomeini Hospital Complex, Tehran, Iran.
    A G2L2 33-year-old woman presented to our clinic with large verrucous warty masses in labia major, perinea and the end portion of her spine measuring about 15 × 7, 9 × 7 and 8 × 8 cm, which had been enlarged following puberty and pregnancy. Her right upper and left lower limbs had gross congenital lymphedema. The masses were removed by superficial partial vulvectomy with a qualified margin and repaired without skin graft. Read More

    Triparametric ultrasound in differentiating multicystic renal masses: a rare presentation of unilateral focal renal lymphangioma.
    Radiol Case Rep 2017 Dec 18;12(4):731-737. Epub 2017 Aug 18.
    Radiology department, Southend University Hospital, Essex, UK.
    We describe a rare case of renal lymphangioma presenting as a focal unilateral multicystic renal mass and document the first reported use of triparametric ultrasound (B-mode, Doppler, and contrast-enhanced ultrasound) in its diagnosis and discrimination from other focal multicystic lesions. Renal lymphangiomas are rare, benign, typically developmental lesions composed of cystic dilatation of the lymphatic ducts, usually occurring bilaterally as perinephric collections or parapelvic cysts mimicking hydronephrosis. Radiologists have an important role in suggesting the diagnosis, as clinical presentation can be nonspecific. Read More

    Lymphangioma cavernous of the small bowel mesentery, an infrequent cause of acute abdomen in adult.
    J Surg Case Rep 2018 Feb 14;2018(2):rjy018. Epub 2018 Feb 14.
    Resident General Surgery, P.U.C.E., Quito-Ecuador.
    Lymphangioma is a benign mass lesion characterized by numerous thin-walled lymphatic spaces that usually manifests in the first few years of life. They generally appear in the head, neck and axillary regions. Abdominal lymphangiomas have been reported however they are rare 5%. Read More

    Bleomycin Sclerotherapy in Lymphangiomas of Head and Neck: Prospective Study of 8 Cases.
    Indian J Otolaryngol Head Neck Surg 2018 Mar 8;70(1):145-148. Epub 2018 Jan 8.
    Department of ENT, Tata Main Hospital, Bistupur, Jamshedpur, 831001 India.
    The aim of this study is to evaluate the role of bleomycin as a primary mode of nonsurgical treatment in lymphangiomas of head and neck and study their complications. This is a prospective study of 8 patients diagnosed with lymphangioma of head and neck presenting to ENT department of Tata main Hospital from December 2014 to January 2017. They were clinically and radiologically evaluated and treated with intralesional injection of bleomycin diluted in normal saline. Read More

    Thirty-day perioperative outcomes in resection of cervical lymphatic malformations.
    Int J Pediatr Otorhinolaryngol 2018 Mar 3;106:31-34. Epub 2018 Jan 3.
    Ann & Robert H Lurie Children's Hospital of Chicago, Department of Otolarynology Head and Neck Surgery, Northwestern Feinberg School of Medicine, 225 E Chicago Ave, Chicago, IL 60610-11, United States.
    Introduction: Limited information exists regarding short-term morbidity in the resection of lymphatic malformations. In order to make informed collaborative medical decisions, clinicians and families would benefit from information on 30-day outcomes and the expected course associated with surgical excision of lymphatic malformations.

    Methods: A retrospective chart review was conducted to develop a case series of patients who underwent resection of lymphatic malformation at a pediatric tertiary care center between June 1, 2007 and September 30, 2016. Read More

    Sirolimus-induced regression of a large orbital lymphangioma.
    Orbit 2018 Feb 6:1-2. Epub 2018 Feb 6.
    b Center for Orbital Diseases, Medical Center and Medical Faculty , University of Freiburg , Freiburg , Germany.
    Microcystic lymphatic malformations are difficult to treat surgically, especially when located in the orbital apex. Recently, pharmacologic inhibition of the mTOR pathway by sirolimus was reported as a safe and efficacious treatment option for lymphatic malformations (also known as lymphangiomas). We report the case of a young male patient in which a unilateral, retrobulbar lymphatic malformation regressed to a large extent under treatment with 1 mg sirolimus given orally twice a day over a period of six months. Read More

    The use of sirolimus in the treatment of giant cystic lymphangioma: Four case reports and update of medical therapy.
    Medicine (Baltimore) 2017 Dec;96(51):e8871
    Neonatal Intensive Care Unit.
    Rationale: Lymphatic malformations (LMs) are rare and benign anomalies resulting from the defective embryological development of the primordial lymphatic structures. Due to their permeative growth throughout all tissue layers, treatment is often challenging. Small asymptomatic lesions can be conservatively managed, while symptomatic lesions require active management. Read More

    Ileal Cystic Lymphangioma presenting with Acute Appendicitis.
    J Indian Assoc Pediatr Surg 2018 Jan-Mar;23(1):36-38
    Department of Pediatric Surgery, National University of Hospital, Singapore.
    Mesenteric lymphatic malformations are rare benign tumors that are most commonly found in children. The presentation of these tumors can be variable. It has been suggested that mesenteric lymphatic malformations are congenital; however, there is evidence that their size may be increased by infection. Read More

    Two cases of hemolymphangioma in the thoracic spinal canal and spinal epidural space on MRI: The first report in the literature.
    Medicine (Baltimore) 2017 Dec;96(52):e9524
    Department of Radiology.
    Rationale: Hemolymphangioma is a rare, noninvasive benign tumor of mesenchymal origin resulting from malformation of vascular and lymphatic vessels. The incidence of hemolymphangioma in the spinal canal is low.

    Patient Concerns: This report describes 2 patients with a lesion located in the thoracic spinal canal or spinal epidural space, who were misdiagnosed with suspected meningioma or suspected schwannoma, respectively, based on magnetic resonance imaging (MRI). Read More

    Percutaneous therapy of a mediastinal lymphangioma with fibrin glue: case report with clinical success after 4 years.
    BMC Surg 2018 Jan 24;18(1). Epub 2018 Jan 24.
    Department of Thoracic Surgery, First Hospital of China Medical University, NO.155 of north Nanjing street, Shenyang, Liaoning, China.
    Background: Lymphangioma of the mediastinum is a rare benign tumor, and most of the cases are treated by a surgical approach.

    Case Presentation: This work reports the case of a 62-year-old female with a large lymphangioma extending from her neck to her abdomen with dysphagia, dyspnea, and cough for 2 months. Because of the location of the mass, only bilateral excision could remove the multiloculated cyst completely. Read More

    A rare cause of small-bowel bleeding: haemorrhagic small-bowel lymphangioma diagnosed by antegrade double-balloon enteroscopy.
    Endoscopy 2018 Apr 19;50(4):E86-E87. Epub 2018 Jan 19.
    Royal Free Unit for Endoscopy, The Royal Free Hospital and University College London (UCL) Institute for Liver and Digestive Health, London, United Kingdom.

    Surgery of multiple lymphangioma in small bowel: a rare case report of chronic gastrointestinal bleeding.
    Ann Surg Treat Res 2018 Jan 28;94(1):52-56. Epub 2017 Dec 28.
    Section of Colon and Rectal Surgery, Department of Surgery, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea.
    Small bowel lymphangioma is a rare benign tumor of the lymphatic system, characterized by the presence of dilated lymphatic spaces and significant gastrointestinal bleeding. Small bowel lymphangiomas are rare in adults and case reports are few. Lymphangiomas in the jejunum or ileum are extremely rare and account for less than 1% of all lymphangiomas. Read More

    Lymphangioma circumscriptum of the tongue: A case with marked hemorrhagic component.
    J Cutan Pathol 2018 Apr 6;45(4):278-281. Epub 2018 Feb 6.
    Department of Pathology and Microbiology, Faculty of Medicine, King Abdullah University Hospital, Jordan University of Science and Technology, Irbid, Jordan.
    Lymphangioma circumscriptum (LC) is considered a superficial variant of lymphangioma with characteristic small lymphatic channels. Diagnosis is routinely made through histopathology in addition to immunostaining. An unusual case of LC presenting as a painless overgrowth of the tongue in a middle-aged male is reported, with emphasis on the clinical and histopathological differential diagnosis. Read More

    National Characteristics of Lymphatic Malformations in Children: Inpatient Estimates and Trends in the United States, 2000 to 2009.
    J Pediatr Hematol Oncol 2018 Apr;40(3):221-223
    Department of Surgery, Division of Urology, Duke University, Durham, NC.
    With ever increasing demands to manage finite resources for health care utilization, we performed an investigation to identify inpatient clinical characteristics and trends in children with lymphatic malformations using the Kids' Inpatient Database, years 2000 to 2009, to help identify populations best suited for resource deployment. Subjects included children 18 years and below with International Classification of Diseases (ICD), ninth revision code: 228.1-lymphangioma, any site. Read More

    Robotic-assisted laparoscopic surgery for pediatric tumors: a bicenter experience.
    J Robot Surg 2017 Dec 29. Epub 2017 Dec 29.
    Service de chirurgie viscérale pédiatrique, Hôpital de Clocheville-CHU de TOURS, 49 boulevard Béranger, 37044, Tours Cedex, France.
    Mini-invasive surgery is more and more integrated in pediatric surgery. The robotic-assisted surgery brought new advantages from which the patient and the surgeon could benefit compared to laparoscopy. Its use in oncological surgery is still controversial. Read More

    Thoracoscopic resection of a huge mediastinal cystic lymphangioma.
    J Thorac Dis 2017 Oct;9(10):E887-E889
    Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
    Mediastinal cystic lymphangioma is an extremely uncommon benign tumor. The patients with mediastinal cystic lymphangioma are often misdiagnosed because of no specific symptoms. The cysts usually are incidentally found and preoperative diagnosis is difficult due to their atypical appearance on imaging studies. Read More

    Acquired lymphangiomas mimicking multiple hallux warts.
    An Bras Dermatol 2017 ;92(5 Suppl 1):11-13
    Department of Dermatology and Venereology, I.R.C.C.S. Istituto Ortopedico Galeazzi, University of Milan - Milan, Italy.
    Lymphangioma is an uncommon benign vascular tumour that involves lymphatic vessels. It can be acquired or, most frequently, congenital. The acquired form presents with dilated lymphatic channels due to an obstruction. Read More

    Epididymal Cystic Lymphangioma Presenting as Scrotal Swelling in a Post Surgery Case of Carcinoma Rectum- A Case Report.
    J Clin Diagn Res 2017 Sep 1;11(9):TD03-TD04. Epub 2017 Sep 1.
    Senior Resident, Department of Paediatrics, Aruna Asaf Ali Hospital, New Delhi, India.
    Cystic lymphangiomas are usually congenital malformations of draining lymphatic channels with most common sites including neck, axilla, mediastinum and retroperitoneum. Occurrence of lymphangiomas in scrotum or inguinal region is a rare entity and epididymal origin of these lesions is even more infrequent. We herein report a case of epididymal lymphangioma detected on USG, which developed after surgical abdominal lymph nodal dissection in an adult patient of carcinoma rectum presenting as painless scrotal swelling. Read More

    Cystic Lymphangioma of the Chest Wall in a 5-Year-Old Male Patient: A Rare and Atypical Localization-A Case Report and Comprehensive Review of the Literature.
    Case Rep Pediatr 2017 23;2017:2083204. Epub 2017 Oct 23.
    1st Department of Pediatric Surgery, Aristotle University of Thessaloniki, General Hospital G. Gennimatas, Thessaloniki, Greece.
    Lymphangioma is a benign congenital malformation. The extremely rare and atypical localization of a lymphangioma in the chest wall was the real motive for the present case study. A 5-year-old boy was admitted to the Emergency Department of the 1st Department of Pediatric Surgery, Aristotle University of Thessaloniki, due to the presence of a mildly painful swelling in the left lateral chest wall, which was first noticed three months ago, after a blunt injury during sport. Read More

    Rare Tumors and Lesions of the Pancreas.
    Surg Clin North Am 2018 Feb;98(1):169-188
    Department of Surgery, Mayo Clinic, 4500 San Pablo Road South, Jacksonville, FL 32224, USA. Electronic address:
    There are a few entities that account for most solid and cystic masses of the pancreas. The pancreas harbors a wide array of diseases, including adenocarcinoma, and its variants, such as anaplastic and adenosquamous carcinoma. Other neoplasms include acinar cell carcinoma, solid pseudopapillary tumor, and sarcomas. Read More

    Lymphangioma secondary to irradiation after mastectomy.
    An Bras Dermatol 2017 May-Jun;92(3):395-397
    Pathological Anatomy Service, Hospital Universitário Polydoro Ernani de São Thiago, Universidade Federal de Santa Catarina (HU-UFSC) - Florianópolis (SC) Brazil.
    Lymphangioma is a rare benign disease of the lymphatic vessels. Typically, they are primary conditions but may be acquired secondarily, such as those caused by irradiation during radiotherapy for the treatment of breast cancer. The local lymphatic obstruction provoked by irradiation causes the appearance of asymptomatic hyaline vesicles on the irradiated skin. Read More

    Rare Case of Pancreatic Cystic Lymphangioma.
    Intern Med 2018 Mar 20;57(6):813-817. Epub 2017 Nov 20.
    Department of Internal Medicine, Okayama Saiseikai General Hospital, Japan.
    Pancreatic cystic lymphangioma is an extremely rare tumor. The characteristic imaging findings are poorly defined, and distinguishing between this disease and other pancreatic cyst-related tumors is very difficult. We herein report a case of a Japanese woman in her 50s with this lesion, located in the tail of the pancreas. Read More

    [Lymphangioma of the breast: about a case].
    Pan Afr Med J 2017 13;28:23. Epub 2017 Sep 13.
    Département de Chirurgie, Cliniques Universitaires de Lubumbashi, Faculté de Médecine, Université de Lubumbashi, Lubumbashi, Republique Démocratique du Congo.
    Lymphangioma is a benign lesion of the lymphatic vessels. It is a rare paediatric condition and it is exceptional among adults. It mainly occurs in the neck, armpit and abdomen. Read More

    Natural Course of Fetal Axillary Lymphangioma Based on Prenatal Ultrasound Studies.
    J Ultrasound Med 2018 May 9;37(5):1273-1281. Epub 2017 Nov 9.
    Departments of Obstetrics and Gynecology, Chiang Mai University, Chiang Mai, Thailand.
    This series and literature review aimed to prenatally characterize the nature of axillary lymphangioma. A total of 30 cases, including our 5 cases, were analyzed. Insights gained from this review are as follows: Septate and nonseptate cysts seem to be different entities. Read More

    Splenic lymphangioma in an adult.
    Saudi Med J 2017 Nov;38(11):1148-1152
    Department of Pathology, Salmaniya Medical Complex, Ministry of Health, Manama, Bahrain, E-mail.
    Splenic lymphangiomas are exceedingly rare benign neoplasms that occur mainly in children. They are commonly seen in the neck and axillary region. Abdominal lymphangiomas accounts for less than 5% of cases. Read More

    Systemic Cystic Angiomatosis Mimicking Metastatic Cancer: A Case Report and Review of the Literature.
    Case Rep Med 2017 11;2017:5032630. Epub 2017 Sep 11.
    Department of Hematology and Oncology, Maimonides Cancer Center, Brooklyn, NY, USA.
    Systemic cystic angiomatosis is a rare benign disorder due to the maldeveloped vascular and lymphatic system with less than 50 cases reported in literature so far. We report here a case of systemic cystic angiomatosis (SCA) with multisystem involvement affecting the neck, thyroid, thoracic cavity, and skeletal system. The patient initially presented in her 4th decade of life with isolated lymphangioma in the neck requiring surgery. Read More

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