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    1 OF 131

    Bleomycin Sclerotherapy in Lymphangiomas of Head and Neck: Prospective Study of 8 Cases.
    Indian J Otolaryngol Head Neck Surg 2018 Mar 8;70(1):145-148. Epub 2018 Jan 8.
    Department of ENT, Tata Main Hospital, Bistupur, Jamshedpur, 831001 India.
    The aim of this study is to evaluate the role of bleomycin as a primary mode of nonsurgical treatment in lymphangiomas of head and neck and study their complications. This is a prospective study of 8 patients diagnosed with lymphangioma of head and neck presenting to ENT department of Tata main Hospital from December 2014 to January 2017. They were clinically and radiologically evaluated and treated with intralesional injection of bleomycin diluted in normal saline. Read More

    Thirty-day perioperative outcomes in resection of cervical lymphatic malformations.
    Int J Pediatr Otorhinolaryngol 2018 Mar 3;106:31-34. Epub 2018 Jan 3.
    Ann & Robert H Lurie Children's Hospital of Chicago, Department of Otolarynology Head and Neck Surgery, Northwestern Feinberg School of Medicine, 225 E Chicago Ave, Chicago, IL 60610-11, United States.
    Introduction: Limited information exists regarding short-term morbidity in the resection of lymphatic malformations. In order to make informed collaborative medical decisions, clinicians and families would benefit from information on 30-day outcomes and the expected course associated with surgical excision of lymphatic malformations.

    Methods: A retrospective chart review was conducted to develop a case series of patients who underwent resection of lymphatic malformation at a pediatric tertiary care center between June 1, 2007 and September 30, 2016. Read More

    Sirolimus-induced regression of a large orbital lymphangioma.
    Orbit 2018 Feb 6:1-2. Epub 2018 Feb 6.
    b Center for Orbital Diseases, Medical Center and Medical Faculty , University of Freiburg , Freiburg , Germany.
    Microcystic lymphatic malformations are difficult to treat surgically, especially when located in the orbital apex. Recently, pharmacologic inhibition of the mTOR pathway by sirolimus was reported as a safe and efficacious treatment option for lymphatic malformations (also known as lymphangiomas). We report the case of a young male patient in which a unilateral, retrobulbar lymphatic malformation regressed to a large extent under treatment with 1 mg sirolimus given orally twice a day over a period of six months. Read More

    The use of sirolimus in the treatment of giant cystic lymphangioma: Four case reports and update of medical therapy.
    Medicine (Baltimore) 2017 Dec;96(51):e8871
    Neonatal Intensive Care Unit.
    Rationale: Lymphatic malformations (LMs) are rare and benign anomalies resulting from the defective embryological development of the primordial lymphatic structures. Due to their permeative growth throughout all tissue layers, treatment is often challenging. Small asymptomatic lesions can be conservatively managed, while symptomatic lesions require active management. Read More

    Ileal Cystic Lymphangioma presenting with Acute Appendicitis.
    J Indian Assoc Pediatr Surg 2018 Jan-Mar;23(1):36-38
    Department of Pediatric Surgery, National University of Hospital, Singapore.
    Mesenteric lymphatic malformations are rare benign tumors that are most commonly found in children. The presentation of these tumors can be variable. It has been suggested that mesenteric lymphatic malformations are congenital; however, there is evidence that their size may be increased by infection. Read More

    Two cases of hemolymphangioma in the thoracic spinal canal and spinal epidural space on MRI: The first report in the literature.
    Medicine (Baltimore) 2017 Dec;96(52):e9524
    Department of Radiology.
    Rationale: Hemolymphangioma is a rare, noninvasive benign tumor of mesenchymal origin resulting from malformation of vascular and lymphatic vessels. The incidence of hemolymphangioma in the spinal canal is low.

    Patient Concerns: This report describes 2 patients with a lesion located in the thoracic spinal canal or spinal epidural space, who were misdiagnosed with suspected meningioma or suspected schwannoma, respectively, based on magnetic resonance imaging (MRI). Read More

    Percutaneous therapy of a mediastinal lymphangioma with fibrin glue: case report with clinical success after 4 years.
    BMC Surg 2018 Jan 24;18(1). Epub 2018 Jan 24.
    Department of Thoracic Surgery, First Hospital of China Medical University, NO.155 of north Nanjing street, Shenyang, Liaoning, China.
    Background: Lymphangioma of the mediastinum is a rare benign tumor, and most of the cases are treated by a surgical approach.

    Case Presentation: This work reports the case of a 62-year-old female with a large lymphangioma extending from her neck to her abdomen with dysphagia, dyspnea, and cough for 2 months. Because of the location of the mass, only bilateral excision could remove the multiloculated cyst completely. Read More

    A rare cause of small-bowel bleeding: haemorrhagic small-bowel lymphangioma diagnosed by antegrade double-balloon enteroscopy.
    Endoscopy 2018 Jan 19. Epub 2018 Jan 19.
    Royal Free Unit for Endoscopy, The Royal Free Hospital and University College London (UCL) Institute for Liver and Digestive Health, London, United Kingdom.

    Surgery of multiple lymphangioma in small bowel: a rare case report of chronic gastrointestinal bleeding.
    Ann Surg Treat Res 2018 Jan 28;94(1):52-56. Epub 2017 Dec 28.
    Section of Colon and Rectal Surgery, Department of Surgery, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea.
    Small bowel lymphangioma is a rare benign tumor of the lymphatic system, characterized by the presence of dilated lymphatic spaces and significant gastrointestinal bleeding. Small bowel lymphangiomas are rare in adults and case reports are few. Lymphangiomas in the jejunum or ileum are extremely rare and account for less than 1% of all lymphangiomas. Read More

    Lymphangioma circumscriptum of the tongue: A case with marked hemorrhagic component.
    J Cutan Pathol 2018 Jan 5. Epub 2018 Jan 5.
    Department of Pathology and Microbiology, Faculty of Medicine, King Abdullah University Hospital, Jordan University of Science and Technology, Irbid, Jordan.
    Lymphangioma circumscriptum (LC) is considered a superficial variant of lymphangioma with characteristic small lymphatic channels. Diagnosis is routinely made through histopathology in addition to immunostaining. An unusual case of LC presenting as a painless overgrowth of the tongue in a middle-aged male is reported, with emphasis on the clinical and histopathological differential diagnosis. Read More

    National Characteristics of Lymphatic Malformations in Children: Inpatient Estimates and Trends in the United States, 2000 to 2009.
    J Pediatr Hematol Oncol 2017 Dec 29. Epub 2017 Dec 29.
    Department of Surgery, Division of Urology, Duke University, Durham, NC.
    With ever increasing demands to manage finite resources for health care utilization, we performed an investigation to identify inpatient clinical characteristics and trends in children with lymphatic malformations using the Kids' Inpatient Database, years 2000 to 2009, to help identify populations best suited for resource deployment. Subjects included children 18 years and below with International Classification of Diseases (ICD), ninth revision code: 228.1-lymphangioma, any site. Read More

    Robotic-assisted laparoscopic surgery for pediatric tumors: a bicenter experience.
    J Robot Surg 2017 Dec 29. Epub 2017 Dec 29.
    Service de chirurgie viscérale pédiatrique, Hôpital de Clocheville-CHU de TOURS, 49 boulevard Béranger, 37044, Tours Cedex, France.
    Mini-invasive surgery is more and more integrated in pediatric surgery. The robotic-assisted surgery brought new advantages from which the patient and the surgeon could benefit compared to laparoscopy. Its use in oncological surgery is still controversial. Read More

    Thoracoscopic resection of a huge mediastinal cystic lymphangioma.
    J Thorac Dis 2017 Oct;9(10):E887-E889
    Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
    Mediastinal cystic lymphangioma is an extremely uncommon benign tumor. The patients with mediastinal cystic lymphangioma are often misdiagnosed because of no specific symptoms. The cysts usually are incidentally found and preoperative diagnosis is difficult due to their atypical appearance on imaging studies. Read More

    Acquired lymphangiomas mimicking multiple hallux warts.
    An Bras Dermatol 2017 ;92(5 Suppl 1):11-13
    Department of Dermatology and Venereology, I.R.C.C.S. Istituto Ortopedico Galeazzi, University of Milan - Milan, Italy.
    Lymphangioma is an uncommon benign vascular tumour that involves lymphatic vessels. It can be acquired or, most frequently, congenital. The acquired form presents with dilated lymphatic channels due to an obstruction. Read More

    Epididymal Cystic Lymphangioma Presenting as Scrotal Swelling in a Post Surgery Case of Carcinoma Rectum- A Case Report.
    J Clin Diagn Res 2017 Sep 1;11(9):TD03-TD04. Epub 2017 Sep 1.
    Senior Resident, Department of Paediatrics, Aruna Asaf Ali Hospital, New Delhi, India.
    Cystic lymphangiomas are usually congenital malformations of draining lymphatic channels with most common sites including neck, axilla, mediastinum and retroperitoneum. Occurrence of lymphangiomas in scrotum or inguinal region is a rare entity and epididymal origin of these lesions is even more infrequent. We herein report a case of epididymal lymphangioma detected on USG, which developed after surgical abdominal lymph nodal dissection in an adult patient of carcinoma rectum presenting as painless scrotal swelling. Read More

    Cystic Lymphangioma of the Chest Wall in a 5-Year-Old Male Patient: A Rare and Atypical Localization-A Case Report and Comprehensive Review of the Literature.
    Case Rep Pediatr 2017 23;2017:2083204. Epub 2017 Oct 23.
    1st Department of Pediatric Surgery, Aristotle University of Thessaloniki, General Hospital G. Gennimatas, Thessaloniki, Greece.
    Lymphangioma is a benign congenital malformation. The extremely rare and atypical localization of a lymphangioma in the chest wall was the real motive for the present case study. A 5-year-old boy was admitted to the Emergency Department of the 1st Department of Pediatric Surgery, Aristotle University of Thessaloniki, due to the presence of a mildly painful swelling in the left lateral chest wall, which was first noticed three months ago, after a blunt injury during sport. Read More

    Rare Tumors and Lesions of the Pancreas.
    Surg Clin North Am 2018 Feb;98(1):169-188
    Department of Surgery, Mayo Clinic, 4500 San Pablo Road South, Jacksonville, FL 32224, USA. Electronic address:
    There are a few entities that account for most solid and cystic masses of the pancreas. The pancreas harbors a wide array of diseases, including adenocarcinoma, and its variants, such as anaplastic and adenosquamous carcinoma. Other neoplasms include acinar cell carcinoma, solid pseudopapillary tumor, and sarcomas. Read More

    Lymphangioma secondary to irradiation after mastectomy.
    An Bras Dermatol 2017 May-Jun;92(3):395-397
    Pathological Anatomy Service, Hospital Universitário Polydoro Ernani de São Thiago, Universidade Federal de Santa Catarina (HU-UFSC) - Florianópolis (SC) Brazil.
    Lymphangioma is a rare benign disease of the lymphatic vessels. Typically, they are primary conditions but may be acquired secondarily, such as those caused by irradiation during radiotherapy for the treatment of breast cancer. The local lymphatic obstruction provoked by irradiation causes the appearance of asymptomatic hyaline vesicles on the irradiated skin. Read More

    Rare Case of Pancreatic Cystic Lymphangioma.
    Intern Med 2017 Nov 20. Epub 2017 Nov 20.
    Department of Internal medicine, Okayama Saiseikai General Hospital, Japan.
    Pancreatic cystic lymphangioma is an extremely rare tumor. The characteristic imaging findings are poorly defined, and distinguishing between this disease and other pancreatic cyst-related tumors is very difficult. We herein report a case of a Japanese woman in her 50s with this lesion, located in the tail of the pancreas. Read More

    [Lymphangioma of the breast: about a case].
    Pan Afr Med J 2017 13;28:23. Epub 2017 Sep 13.
    Département de Chirurgie, Cliniques Universitaires de Lubumbashi, Faculté de Médecine, Université de Lubumbashi, Lubumbashi, Republique Démocratique du Congo.
    Lymphangioma is a benign lesion of the lymphatic vessels. It is a rare paediatric condition and it is exceptional among adults. It mainly occurs in the neck, armpit and abdomen. Read More

    Natural Course of Fetal Axillary Lymphangioma Based on Prenatal Ultrasound Studies.
    J Ultrasound Med 2017 Nov 9. Epub 2017 Nov 9.
    Departments of Obstetrics and Gynecology, Chiang Mai University, Chiang Mai, Thailand.
    This series and literature review aimed to prenatally characterize the nature of axillary lymphangioma. A total of 30 cases, including our 5 cases, were analyzed. Insights gained from this review are as follows: Septate and nonseptate cysts seem to be different entities. Read More

    Splenic lymphangioma in an adult.
    Saudi Med J 2017 Nov;38(11):1148-1152
    Department of Pathology, Salmaniya Medical Complex, Ministry of Health, Manama, Bahrain, E-mail.
    Splenic lymphangiomas are exceedingly rare benign neoplasms that occur mainly in children. They are commonly seen in the neck and axillary region. Abdominal lymphangiomas accounts for less than 5% of cases. Read More

    Systemic Cystic Angiomatosis Mimicking Metastatic Cancer: A Case Report and Review of the Literature.
    Case Rep Med 2017 11;2017:5032630. Epub 2017 Sep 11.
    Department of Hematology and Oncology, Maimonides Cancer Center, Brooklyn, NY, USA.
    Systemic cystic angiomatosis is a rare benign disorder due to the maldeveloped vascular and lymphatic system with less than 50 cases reported in literature so far. We report here a case of systemic cystic angiomatosis (SCA) with multisystem involvement affecting the neck, thyroid, thoracic cavity, and skeletal system. The patient initially presented in her 4th decade of life with isolated lymphangioma in the neck requiring surgery. Read More

    Cystic intra-abdominal masses in children.
    Pediatr Rep 2017 Oct 6;9(3):7284. Epub 2017 Oct 6.
    Division of Pediatric General, Thoracic and Minimally Invasive Surgery, AOU Città della Salute e della Scienza, Regina Margherita Children's Hospital, Torino, Italy.
    Benign intra-abdominal cystic masses in infancy are fairly uncommon and their etiopathogenesis, histology and clinical presentation differ significantly. Our aim is to report our experience in their treatment in order to discuss the best diagnostic and treatment modality. The medical records of 5 children (2M, 3F) with cystic intraabdominal masses referred to our hospital between November 2012 and September 2016, were retrospectively reviewed. Read More

    Human Immunodeficiency Virus-Negative-Associated Lymphangioma-like Kaposi's Sarcoma with Variable Clinical Presentations.
    J Am Podiatr Med Assoc 2017 Sep;107(5):461-466
    Lymphangioma-like Kaposi's sarcoma (LLKS) is a rare histologic variant of KS. Kaposi's sarcoma is also known as human herpesvirus type 8. The clinical presentation of the LLKS lesion is highly unusual and similar to that of classic KS but with multinodular vascular tumors and lymphedema. Read More

    Spontaneous Regression of Lymphangiomas in a Single Center Over 34 Years.
    Plast Reconstr Surg Glob Open 2017 Sep 25;5(9):e1501. Epub 2017 Sep 25.
    Department of Plastic and Reconstructive Surgery, Lymph Clinic, Saitama Children's Medical Center, Saitma, Japan; Department of Pediatric Surgery, Saitama Children's Medical Center, Saitma, Japan; and Department of Plastic and Reconstructive Surgery, The University of Tokyo, Tokyo, Japan.
    Background: A lymphangioma, also called a lymphatic malformation, is a congenital condition that frequently occurs in young children. It is classified into 3 groups depending on the size of the cysts (macrocystic, microcystic, and mixed). Spontaneous regression occurs in some cases; however, the characteristics of patients who show regression have not been studied previously. Read More

    Evaluation of lymphatic vessel dilatations by anterior segment swept-source optical coherence tomography: case report.
    BMC Ophthalmol 2017 Oct 23;17(1):194. Epub 2017 Oct 23.
    Faculty of Medicine Department of Ophthalmology, Semmelweis University, Budapest, Hungary.
    Background: Conjunctival lymphangiectasia is a rare condition presumably caused by the obstruction of lymphatic channels or by an abnormal connection between conjunctival lymphatic and blood vessels. Diagnosis is based on clinical appearance and histology. We report a case of conjunctival lymphangiectasia in which anterior segment optical coherence tomography (OCT) was used to assist the diagnosis and the planning of the biopsy location. Read More

    Large cystic lympangioma of the pancreas: a case reportum.
    Ann R Coll Surg Engl 2018 Jan 19;100(1):e12-e14. Epub 2017 Oct 19.
    Department of Surgical Gastroenterology, Sakra World Hospital, Bengaluru , Karnataka , India.
    Lymphangioma of the pancreas is rare and presents as a large cystic mass in the retroperitoneum. The pancreatic origin can be confirmed by careful evaluation of cross sectional imaging. Preoperative differentiation from other pancreatic cystic neoplasms is difficult but possible. Read More

    Inconsistency in classifying vascular anomalies: What's in a name?
    Pediatr Blood Cancer 2018 Mar 8;65(3). Epub 2017 Oct 8.
    Division of Pediatric Hematology Oncology, University of North Carolina School of Medicine, Chapel Hill, North Carolina.
    Background: Vascular anomalies are a heterogeneous group of disorders seen in children and adults. A standard nomenclature for classification has been offered by the International Society for the Study of Vascular Anomalies. Its application is important for communication among the multiple specialties involved in the care of patients and for planning treatment, as well as for research and billing. Read More

    Cystic lymphangioma of the lesser omentum in a pregnant woman: a case report and review of the literature.
    J Exp Ther Oncol 2017 Sep;11(2):155-158
    Department of Clinics Pathalogy, Ankara Numune Education and Research Hospital, Ankara, Turkey.
    Objective: Lymphangiomas are rare benign tumors which are generally seen in pediatric population and the etiopathogenesis has not yet been understood. They occasionally occur in the head and neck or axillary region with only 5% of them being located in the abdominal or mediastinal cavity. These tumors may be asymptomatic or may cause acute abdominal symptoms due to the location and extention. Read More

    Cavernous lymphangioma of the tongue in an adult: a case report.
    J Istanb Univ Fac Dent 2017 3;51(2):49-53. Epub 2017 Apr 3.
    Department of Oral and Maxillofacial Surgery Faculty of Dentistry Istanbul University Turkey.
    Lymphangioma is a benign hamartomatous lesion caused by congenital malformation of the lymphatic system. This benign tumor is detected most commonly at birth or in early childhood but rarely in adults. On clinical examination, most lymphangiomas contain clear lymph fluid, but some may present as transparent vesicles containing red blood cells due to hemorrhage. Read More

    Acquired progressive lymphangioma: Case report with partial response to imiquimod 5% cream.
    Pediatr Dermatol 2017 Nov 21;34(6):e302-e304. Epub 2017 Sep 21.
    Department of Dermatology, School of Medicine, Marmara University, Istanbul, Turkey.
    Acquired progressive lymphangioma (APL), or benign lymphangioendothelioma, is an unusual entity derived from vascular structures. Clinically and histopathologically it may resemble Kaposi's sarcoma and well-differentiated angiosarcoma, causing a diagnostic problem. We report an individual with APL initially diagnosed with Kaposi's sarcoma who underwent unnecessary laboratory testing. Read More

    An acute presentation of pediatric mesenteric lymphangioma: a case report and literature overview.
    Acta Chir Belg 2017 Sep 19:1-5. Epub 2017 Sep 19.
    a Departments of General Surgery , Mariaziekenhuis , Overpelt , Belgium.
    Introduction: Lymphangioma accounts for 5% of benign pediatric tumors and less than 1% is located in the abdomen. While mesenteric lymphatic malformation or mesenteric lymphangioma (ML), mostly appears asymptomatic in adults, an acute clinical presentation is seen more often in children. Symptoms can mimic obstruction or peritonitis and diagnosis can therefore be challenging. Read More

    Treatment of Tongue Lymphangioma with Intralesional Combination Injection of Steroid, Bleomycin and Bevacizumab.
    Arch Craniofac Surg 2017 Mar 25;18(1):54-58. Epub 2017 Mar 25.
    Department of Plastic Surgery, Kyung Hee University College of Medicine, Seoul, Korea.
    Lymphangioma is a congenital malformed lymphatic tumor that rarely involves the tongue. In our clinic, a 10-year-old female presented with lymphangioma circumscriptum involving the right two-thirds of the tongue. We administered an intralesional combination injection of triamcinolone, bleomycin, and bevacizumab as a treatment. Read More

    A rare case of giant mesenteric cystic lymphangioma of the small bowel in an adult: A case presentation and literature review.
    Acta Gastroenterol Belg 2016 Sep-Dec;79(3):491-493
    Background : Lymphangiomas are tumours that are often found in the head and neck in children and, rarely, in adults. Among all lymphangiomas in adults, the small bowel mesentery type accounts for less than 1%. We aim to present a rare case of small bowel symptomatic cystic lymphangioma in an adult patient, as well as its diagnosis and subsequent treatment. Read More

    Malignant perivascular epithelioid cell tumor of the orbit: Report of a case and review of literature.
    Indian J Ophthalmol 2017 Sep;65(9):889-891
    Department of Ocular Pathology, Sankara Nethralaya, Medical Research Foundation, Chennai, Tamil Nadu, India.
    Perivascular epithelioid cell tumor (PEComa) is a rare neoplasm considered to arise from myomelanocytic cell lineage. The uterus is reportedly the most common site to be involved. Orbital PEComa is extremely rare with only two cases reported till date. Read More

    When Fever, Leukocytosis, and Right Lower Quadrant Pain Is Not Appendicitis.
    Pediatr Emerg Care 2017 Sep;33(9):e46-e47
    From the *Emergency Medicine Attending, and †Division of Emergency Medicine, Maimonides Medical Center, Brooklyn, NY.
    Mesenteric cystic lymphangioma (MCL) is an uncommon, benign, slow-growing abdominal tumor that is derived from the lymphatic vessels (World J Gastroenterol. 2012;18:6328-6332, Radiographics. 1994;14:729-737). Read More

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