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Sisli Etfal Hastan Tip Bul 2020 10;54(2):222-226. Epub 2019 Oct 10.

Department of Pediatrics, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.

Objectives: In our study, we aimed to investigate the clinical characteristics and cancer frequency in patients referred to our pediatric oncology outpatient clinic for lymphadenopathy.

Methods: The charts of patients admitted to our pediatric oncology outpatient clinics for lymphadenopathy between January 2014, and December 2016 were retrospectively reviewed in this study. Age, gender, duration of complaints, previous therapies, systemic signs and symptoms, lymph node characteristics and laboratory findings were recorded. Read More

Int Cancer Conf J 2020 Jul 27;9(3):162-167. Epub 2020 May 27.

Department of Surgical Oncology, Gifu University Graduate School of Medicine, Gifu, Japan.

A 75-year-old woman was diagnosed with anemia during hospitalization for the treatment of right superior ophthalmic arteriovenous fistula. Colonoscopy revealed an entire circumference of type 2 tumor in the ascending colon. Computed tomography showed ascending colon wall thickening, a tumor with a maximum diameter of 32 mm on the right external iliac artery and multiple low-density nodules in the spleen. Read More

Respir Investig 2020 Jun 20. Epub 2020 Jun 20.

Department of Thoracic Surgery, Kyoto City Hospital, Kyoto, Japan.

A 53-year-old man was referred to our hospital for examination of a nodule in the right hilar region observed on a chest roentgenogram. Computed tomography and magnetic resonance imaging revealed a 34 × 32-mm multilocular cystic mass with partial calcification adjacent to the hilar structures in the right upper lung lobe. The mass was resected using video-assisted thoracoscopic surgery and identified as pulmonary cystic lymphangioma through postoperative histopathological analysis. Read More

Surg Case Rep 2020 Jun 18;6(1):140. Epub 2020 Jun 18.

Department of Gastroenterological Surgery II, Hokkaido University Faculty School of Medicine, North 15 West 7, Kita-ku, Sapporo, Hokkaido, 0608638, Japan.

Background: Lymphangioma is a benign malformation of the lymphatic system and is often found in the neck and axilla, the orbit, the mediastinum, etc. However, isolated splenic lymphangioma is a rare disease in young women, and its treatment is controversial. We report a case of laparoscopic partial splenectomy for isolated splenic lymphangioma in a young woman. Read More

Int J Surg Case Rep 2020 Jun 11;72:255-259. Epub 2020 Jun 11.

Department of Diagnostic Pathology, Hamamatsu University School of Medicine, Hamamatsu, Japan.

Introduction: Lymphangiomas are benign cystic tumors which arise from congenital malformations of the lymphatic system and are extremely rare in adulthood. We report a case of adult lymphangioma of the axilla that was removed after identifying the feeding lymphatic vessel using an indocyanine green (ICG) fluorescence imaging system.

Presentation Of Case: A 35-year old woman presented to our hospital with a rapidly growing mass on her left axilla. Read More

Radiol Case Rep 2020 Aug 9;15(8):1189-1193. Epub 2020 Jun 9.

Student Research Committee, Sari Branch, Islamic Azad University, Sari, Iran.

Generalized lymphangiomatosis (GLA) is a rare lymphatic abnormality, mostly affects children and young individuals and can be a diagnostic challenge because of wide spectrum of clinical manifestations. A 26-year-old woman presented to the emergency department of our institution with respiratory distress and hypoxia. The patient reported similar episodes for the past 10 years without a definite diagnosis. Read More

Semin Diagn Pathol 2020 May 5. Epub 2020 May 5.

University of Florida College of Medicine Department of Pathology, Immunology and Laboratory Medicine P.O. Box 100275 1600 SW Archer Road Gainesville, FL 32610-0275.

This review focuses on the diagnosis of select benign processes, ranging from reactive entities to heterotopic tissues to neoplasms, which may occur in the mediastinum. Currently, the mediastinum can be evaluated and biopsied with endoscopic procedures. Therefore, cytopathology specimens, fine needle aspirations, and small biopsies play an important role in the diagnosis of these lesions. Read More

Oral Maxillofac Surg 2020 Jun 13. Epub 2020 Jun 13.

The Vascular Birthmark Foundation, VBF Europe, VBF Italy, PO Box 106, Latham, NY, 12110, USA.

Oral Maxillofac Surg 2020 Jun 12. Epub 2020 Jun 12.

Division of Otolaryngology, Maggiore della Carità Hospital, University of Eastern Piedmont, Novara, Italy.

In this reply to a letter, the Authors discuss the raised points regarding the nomenclature and management of Lymphatic Malformations / Lymphangiomas. Read More

World J Clin Cases 2020 May;8(10):1973-1978

Department of Nuclear Medicine and PET/CT Center, Tianjin First Center Hospital, Nankai University, Tianjin 300192, China.

Background: Lymphangioma is a rare benign cystic tumor believed to be a proliferation of heterotopic lymphocytes. It is caused by congenital lymphatic dysplasia or other acquired factors related to surgery, trauma, infection, or cancer. In this article, we present the case of an adult patient who underwent multi-modal imaging and whose condition was finally confirmed to be multiple cystic lymphangiomas by pathological examination. Read More

Am J Obstet Gynecol 2020 Jun 3. Epub 2020 Jun 3.

Nuffield Department of Women's and Reproductive Health, University of Oxford, John Radcliffe Hospital, Oxford, UK. Electronic address:

Background: Third-trimester scans are increasingly used to try to prevent adverse outcomes associated with abnormalities of fetal growth. Unexpected fetal malformations detected at third-trimester growth scans are rarely reported.

Objective: To determine the incidence and type of fetal malformations detected in women attending a routine third-trimester growth scan. Read More

An Bras Dermatol 2020 Jul - Aug;95(4):477-479. Epub 2020 May 5.

Bibliometric Investigation Unit, Universidad San Ignacio de Loyola, Lima, Peru.

Lymphangioma is a rare and understudied pathology that is usually detected in the first decade of life, and its appearance in adults is rare. This report details a 51-year-old man with morbid obesity who presented, for the last eight months, multiple asymmetric tumor lesions with extension to the scrotal region. The diagnosis of circumscribed lymphangioma with associated infection was confirmed. Read More

Med J Malaysia 2020 May;75(Suppl 1):48-50

Airlangga University, Faculty of Medicine, Department of Surgery, Jalan Mayjen. Prof. Dr. Moestopo 6-8 Surabaya, Jawa Timur, Indonesia 60119.

Chylous mesenteric cyst is a very rare case, with some vague clinical findings, and it is hard to establish the diagnosis before surgery. The most common complaints post-surgery are abdominal pain and abdominal distention. We report a case of chylous mesenteric cyst in a 4-year-old boy with chief complaint of a lump in the abdomen. Read More

J Ayub Med Coll Abbottabad 2020 Jan- Mar;32(1):42-45

Department of Paediatric Surgery, Children Hospital and Institute of Child Health, Multan, Pakistan.

Background: This study is aimed to assess the efficacy of intralesional Bleomycin sclerotherapy in macrocystic lymphangioma in children.

Methods: This prospective observational study included 40 children diagnosed with macrocystic lymphangioma and treated with intralesional injection of Bleomycin from March 2016 to Dec 2018. We excluded all the patients above 12 years of age, lesions with size less than 2 cm, and post-surgical recurrent lesions. Read More

Int J Surg Case Rep 2020 8;71:176-178. Epub 2020 May 8.

Department of Pediatric Surgery, West China Hospital of Sichuan University, Chengdu, Sichuan Province, People's Republic of China.

Introduction: Mesothelial cyst (MC) is very uncommon in clinic, which could occasionally occur in peritoneal, retroperitoneal or even pleural cavity.

Presentation Of Case: We hereby described an infant patient with retroperitoneal MC who was misdiagnosed as congenital choledochal cyst by both radiologists and clinicians. A choledochal cyst resection with hepatojejunostomy under the da Vinci surgical system was routinely prepared for this patient but a local resection for the whole lesion was unexpectedly performed during the operation. Read More

J Surg Case Rep 2020 May 15;2020(5):rjaa031. Epub 2020 May 15.

Medico, Ministerio de Salud Publica, Quito, Ecuador.

The lymphangioma is a benign neoplasm, mostly connate, it occurs more often in children. It is more frequently located in the head-neck region, as well as in the armpit, and less frequently in the abdomen. The diagnosis, as well as their appearance is variant, they can be asymptomatic depending on the size. Read More

Acta Otorrinolaringol Esp 2020 May 17. Epub 2020 May 17.

Hospital Universitario de Gran Canaria Dr. Negrín, Santa Brígida (Las Palmas), España.

Int J Surg Pathol 2020 May 18:1066896920924120. Epub 2020 May 18.

Queen Elizabeth Hospital, Hong Kong SAR China.

Composite hemangioendothelioma is a rare vascular tumor morphologically comprising several distinct vascular components and exhibits a borderline malignant potential. We described the case of a 53-year-old female who presented with an infiltrative mass in the paravertebral soft tissue. The tumor showed discrete nests of synaptophysin-expressing epithelioid cells accompanied by rich vasculature, features highly reminiscent of sympathetic paraganglioma. Read More

Am J Clin Dermatol 2020 May 14. Epub 2020 May 14.

Department of Radiation Oncology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Radiation therapy is a mainstay for the treatment of primary malignancies and metastatic disease and is associated with several dermatological adverse events that are underreported in the literature. The objective of this paper was to review the literature regarding cutaneous manifestations associated with radiation therapy in order to promote awareness of the cutaneous radiation therapy-associated adverse effects. This extensive literature review was performed using the Pubmed and Embase databases. Read More

Gan To Kagaku Ryoho 2020 Mar;47(3):534-536

Dept. of Gastrointestinal Surgery, Saitama Medical University International Medical Center.

A 72-year-old woman who underwent colorectal endoscopy because of positive fecal occult blood test results was diagnosed with ascending colon cancer.Preoperative CT revealed advanced ascending colon cancer and portosystemic shunt between the ileocecal vein and inferior vena cava.It was necessary to cut the shunt when ileocecal resection was performed. Read More

Rev Gastroenterol Peru 2020 Jan-Mar;40(1):64-68

Servicio de Gastroenterología, Hospital Nacional Arzobispo Loayza, Lima, Perú.

Lymphangiomas are benign lesions due to a developmental malformation in the lymphatic system that occurs during the embryonic stage. They are more frequent in children. They can be found in the abdominal cavity, being the involvement of the gastrointestinal tract occasionally. Read More

Gulf J Oncolog 2020 Jan;1(32):63-65

Department of Pediatric Urology, MITR Hospital, Kharghar, India.

A 5-year old boy presented with a picture of communicating hydrocele and was discovered to have an abdominoscrotal lymphangioma after undergoing hydrocele surgery. Upon initial presentation the lymphangioma was missed and the child underwent inguinal approach surgery for hydrocele. The lymphangioma was then noticed as an abdominal lump due to a rapid increase in size within 1 week following the hydrocele surgery. Read More

Pan Afr Med J 2020 24;35:20. Epub 2020 Jan 24.

Department of Pediatric Surgery, CHU Hassan II, Faculty of Medicine and Pharmacy, Sidi Mohamed Ben Abdellah University, Fez, Morocco.

Omental cystic lymphangioma is a rare benign intraabdominal anomaly with uncertain etiology, predominantly occurring in children. Most cases of abdominal lymphangioma are asymptomatic. However, patients may occasionally present with acute abdomen because of an intestinal obstruction or peritonitis caused by infected cysts, hemorrhaging, and/or torsion. Read More

BMJ Case Rep 2020 Apr 26;13(4). Epub 2020 Apr 26.

Radiodiagnosis, SGPGIMS, Lucknow, Uttar Pradesh, India

A 36-year-old woman presented to the radiology department with a history of gradual increase in the size of her left breast and greenish discolouration of the skin over it since 1.5 months. Physical examination revealed a soft non-tender mass involving the whole of the left breast. Read More

Dermatol Ther 2020 Apr 27:e13463. Epub 2020 Apr 27.

Department of Special Patient Care, Hospital Dentistry Clinic, UCLA School of Dentistry, Los Angeles, California, USA.

Lymphangioma circumscriptum is a benign lymphatic malformation that usually presents at birth or early childhood. Acquired oral lymphangioma has been reported secondary to radiation therapy and denture-induced trauma due to damage to previously normal lymphatics. To the best of our knowledge, this is the first report of acquired oral lymphangioma due to childhood tuberculous adenitis. Read More

J Vasc Surg Venous Lymphat Disord 2020 Apr 20. Epub 2020 Apr 20.

Department of Surgery A, Galilee Medical Center, Nahariya, Israel. Electronic address:

Lymphangioma is a malformation of the lymphatic system for which surgical excision is a possible treatment. However, complete excision may be hindered by the lesion's size, anatomic location, unclear borders, and invasion into adjacent tissues. We describe a 14-year-old girl who presented with a rapidly progressing axillary swelling. Read More

Med Arch 2020 Feb;74(1):28-33

Department of Dermatology and Venereology, the Royal Medical Services (RMS), Amman, Jordan.

Introduction: Anogenital area is a small compartment in the human body. Recognition of various dermatological conditions affecting this area in children is essential for any physician involved in pediatric examination and evaluation.

Aim: To assess the nature, diagnoses, and gender differences of Anogenital lesions in pediatric patients presented to Royal Medical Services (RMS) general dermatology clinics, who were five year old and younger. Read More

World J Gastroenterol 2020 Apr;26(13):1540-1545

Department of Gastroenterology, Air Force Medical Center, Beijing 100142, China.

Background: Hemolymphangiomas are rare malformations composed of both lymphatic and vascular vessels and are located in the pancreas, spleen, mediastinum, . Small intestinal hemolymphangioma is extremely rare and often presents as obscure gastrointestinal bleeding. It is rarely diagnosed correctly before the operation. Read More

J Otolaryngol Head Neck Surg 2020 Apr 19;49(1):19. Epub 2020 Apr 19.

Department of Otolaryngology Head and Neck Surgery, Ann and Robert H. Lurie Children's Hospital of Chicago, Northwestern Feinberg School of Medicine, 225 E Chicago Ave, Chicago, IL, 60610, USA.

Background: Previous literature has reported on the incidence of short-term complications following resection of cervical lymphatic malformations (LMs) in children, however no research has yet investigated the long-term symptomatic course in these patients. This study aims to provide families and providers with an understanding of expectations for long-term symptom control, specifically in association with subsequent upper respiratory infections (URIs).

Methods: A retrospective chart review produced a case series of patients who underwent resection of cervical LM at a pediatric tertiary care center between 2007 and 2016. Read More

Abdom Radiol (NY) 2020 Apr 15. Epub 2020 Apr 15.

Department of Digestive Diagnostic and Interventional Radiology, University Hospital Claude Huriez - Regional University Hospital Center, rue Michel Polonoski, 59037, Lille Cedex, France.

Purpose: The aim of the study is to describe the imaging features, complications and differential diagnoses of abdominal cystic lymphangiomas (ACLs).

Results: ACLs are benign lymphatic malformations that mainly arise in the subperitoneal space and the retroperitoneum. The typical presentation of an ACL is a multilocular lesion with homogenous serous content, presenting a thin wall and septa, usually free from adjacent organ compression. Read More

SAGE Open Med Case Rep 2020 2;8:2050313X20915415. Epub 2020 Apr 2.

Department of Otolaryngology-Head & Neck Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.

Perforation of the larynx is very rare but may result in severe airway complications that include pneumothorax, pneumonia, mediastinitis, and retropharyngeal abscess. If conservative treatment fails, aggressive treatments including reconstructive surgery with pedicle flap are considered. Negative pressure wound therapy has been used for large skin defects, necrotizing fasciitis, pharyngocutaneous fistula, stoma dehiscence, osteoradionecrosis of the mandible, chyle fistula, flap failure, and lymphangioma in the field of head and neck surgery. Read More

J Visc Surg 2020 Apr 10. Epub 2020 Apr 10.

Digestive Surgery Department, Dupuytren University Hospital, 87000 Limoges, France; University Limoges, CNRS, XLIM, UMR 7252, 87000 Limoges, France.

J Lasers Med Sci 2020 15;11(2):234-237. Epub 2020 Mar 15.

School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.

Lymphangioma is a rare vascular anomaly that affects the lymphatic vessels. Its etiology is not yet clear and it usually occurs in the head and neck region. This pathology is commonly diagnosed in childhood and there is no consensus about the most effective treatment of it. Read More

J Lasers Med Sci 2020 15;11(2):226-227. Epub 2020 Mar 15.

Men's Health & Reproductive Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Lymphangioma is a sporadic benign tumor of the bladder. It is a congenital disorder and based on the size of lymphatic spaces, it is divided into 3 types of capillary, cavernous, and cystic. In this paper, we presented a 40-year-old woman with microscopic hematuria and a normal urinary ultrasound. Read More

World Neurosurg 2020 04;136:427

Kaiser Permanente, Kaiser Sacramento Medical Center, Sacramento, California, USA.

World Neurosurg 2020 04;136:426

Neurosurgery Unit, Clínica La Pequeña Familia, Buenos Aires, Argentina.

J Visc Surg 2020 Jun 20;157(3):217-230. Epub 2020 Mar 20.

Clinique de chirurgie digestive et endocrinienne, institut des maladies de l'appareil digestif, centre hospitalier universitaire de Nantes, 44093 Nantes, France. Electronic address:

Discovery of an adrenal mass is nowadays a frequent situation. While adrenal tumors can cause a variety of symptoms, more often than not they are diagnosed incidentally on imaging exams such as CT-scan or MRI performed for another purpose. However, any retroperitoneal supra-renal mass can have an extra-adrenal origin. Read More

BMJ Case Rep 2020 Mar 17;13(3). Epub 2020 Mar 17.

Trauma and Surgical Oncology Unit, Royal Adelaide Hospital, Adelaide, South Australia, Australia.

Mesenteric lymphangioma is a benign cystic tumour of the lymphatic vessels that occurs rarely in adults. Due to the infrequency of cases and the insidious presentation, these tumours can be diagnosed late and become massive. Resection of mesenteric lymphangioma in its entirety is the recommended management in order to prevent recurrence. Read More

Asian J Neurosurg 2020 Jan-Mar;15(1):168-171. Epub 2020 Feb 25.

Department of Neurosurgery, Government Medical College, Thrissur, Kerala, India.

Orbital lymphangioma is an intra-orbital, nonencapsulated, congenital vascular tumor with a propensity for recurrent hemorrhage. It is a common vascular tumor in children below 10 years of age. Adult orbital intraconal lymphangiomas are very rare. Read More

Oman J Ophthalmol 2020 Jan-Apr;13(1):43-45. Epub 2020 Feb 17.

Department of Oculoplasty, Dr. Shroff's Charity Eye Hospital, New Delhi, India.

Lymphangioma is a benign hamartomatous lesion of vascular system which frequently involves orbit and ocular adnexa. A 35-year-old male patient presented with a subconjunctival mass extending from limbus to fornices. There was a history of recurrent swellings following episodes of upper respiratory tract infection. Read More

Rev Bras Anestesiol 2020 Jan - Feb;70(1):59-62. Epub 2020 Feb 19.

Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Serviço de Anestesiologia, Lisboa, Portugal.

The Ex- Utero Intrapartum Treatment (EXIT) is a surgical procedure performed in cases of expected postpartum fetal airway obstruction, allowing the establishment of patent airway while maintaining placental circulation. Anesthesia for EXIT procedure has several specific features such as adequate uterine relaxation, maintenance of maternal blood pressure fetal anesthesia and fetal airway establishment. The anesthesiologist should be aware of these particularities in order to contribute to a favorable outcome. Read More

J Indian Assoc Pediatr Surg 2020 Mar-Apr;25(2):80-84. Epub 2020 Jan 28.

Department of Pediatric Surgery, Indira Gandhi Institute of Child Health, Bengaluru, Karnataka, India.

Introduction: The management of lymphatic malformations (LMs) continues to improve with advancement in molecular genetics, imaging, and treatment options. However, the management of tongue LMs remains a challenge due to the location, function involved, and long-term disabilities. We propose injection sclerotherapy with bleomycin in the management of spectrum of tongue LMs. Read More

Anticancer Res 2020 Mar;40(3):1631-1636

Department of Otorhinolaryngology, China Medical University Hospital, Taichung, Taiwan, R.O.C

Lymphangioma insults in adults are uncommon and the occurrence in the oropharynx is extremely rare. Although disease history and clinical symptoms may help in distinguishing it from malignant tumors, the pathophysiology of lymphangioma via histological examinations should be established for convenient and precise diagnosis. We present a 20-year-old male with lymphangioma in the right oropharynx, and the multiple-angle examination and treatment plan used. Read More

Ophthalmic Plast Reconstr Surg 2020 Feb 24. Epub 2020 Feb 24.

Department of Ophthalmology, University of Washington School of Medicine, Seattle, Washington.

A 22-year-old male presented with spontaneous unilateral hemolacria and was found to have complete opacification of the ipsilateral nasolacrimal sac and duct. Endoscopic biopsy with histopathologic analysis revealed the diagnosis of nasolacrimal lymphangioma. Additional management included nasolacrimal stenting, and there was no hemolacria recurrence or epiphora. Read More

J Ultrasound Med 2020 Mar 2. Epub 2020 Mar 2.

Obstetrics and maternal-fetal Medicin, Hospital Necker Enfants Malades, APHP, University Paris Descartes, Paris, France.

Congenital orbital masses are rare disorders. A wide variety of lesions, including malignant and benign tumors, may develop around the orbit; hemangioma, lymphangioma, and optic nerve meningioma are the most common. Counseling for the prognosis and postnatal treatment depends on antenatal suspicion. Read More

Int J Surg Case Rep 2020 11;67:250-253. Epub 2020 Feb 11.

Department of Surgery, University of the Philippines-Philippine General Hospital, Philippines.

Introduction: Splenic disease are uncommon and primary tumors of the spleen are very rare. These are classified as splenic cyst, benign and malignant tumors. Splenic lymphangioma is a rare, slow-growing benign tumor of the spleen. Read More

Case Rep Surg 2020 28;2020:8932017. Epub 2020 Jan 28.

Department of Pathology, Maulana Azad Medical College, New Delhi, India.

. Omental cysts are a part of cystic lymphangiomas and are benign proliferations of ectopic lymphatics without a communication with the normal lymphatic system. They commonly involve the neck in the pediatric population and are uncommon at other sites and occur rarely in adults. Read More

BMJ Case Rep 2020 Feb 13;13(2). Epub 2020 Feb 13.

Radiodiagnosis, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India

Indian J Dermatol Venereol Leprol 2020 Mar-Apr;86(2):230

Department of Dermatology, Topiwala National Medical College and B.Y.L. Nair Ch. Hospital, Mumbai, Maharashtra, India.

The incidence of lymphangioma is 1.2 to 2.8/1000 newborns. Read More

Adv Exp Med Biol 2020 ;1226:51-56

Department of Cardiothoracic Surgery, New York Presbyterian Hospital, Weill Cornell Medicine, New York City, NY, USA.

Cardiac tumors are found in less than 1% of adult and pediatric autopsies. More than three-fourths of primary cardiac neoplasms are benign, with myxomas and rhabdomyomas being the most common cardiac tumors seen in adults and children, respectively. Primary malignant cardiac tumors are extremely rare, whereas metastatic lesions can be seen in approximately 8% of patients dying from cancer. Read More