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    TNFΔARE Mice Display Abnormal Lymphatics and Develop Tertiary Lymphoid Organs in the Mesentery.
    Am J Pathol 2017 Feb 6. Epub 2017 Feb 6.
    Inflammation Research Network and Smooth Muscle Research Group, Department of Physiology & Pharmacology, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada. Electronic address:
    Chronic inflammatory diseases are associated with a persistent and enhanced response to environmental antigens. As an adaptive response to this exaggerated immune state, affected tissue typically develops tertiary lymphoid organs. Studies of Crohn disease (CD), a chronic inflammatory disease of the intestinal tract, report tertiary lymphoid organs present within the mucosal wall, along with other lymphatic diseases, such as lymphangiogenesis and obstructed lymphatic vessels. Read More

    A Quick Reference on Hypocalcemia.
    Vet Clin North Am Small Anim Pract 2017 Mar 22;47(2):249-256. Epub 2016 Dec 22.
    The Ohio State University, 317 West 6th Avenue, Columbus, OH 43201, USA. Electronic address:
    Primary hypoparathyroidism should be considered in dogs with vague signs, including tremors, facial rubbing, and seizures. Ionized hypocalcemia should be considered in dogs with protein-losing enteropathy, especially lymphangiectasia caused by hypovitaminosis D. Ionized hypocalcemia typically occurs only in advanced chronic kidney disease. Read More

    Histopathology of Conjunctivochalasis Compared to Normal Conjunctiva.
    J Ophthalmic Vis Res 2016 Oct-Dec;11(4):345-349
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Massachusetts, Boston, USA.
    Purpose: To evaluate the histopathologic changes in the conjunctiva of patients with conjunctivochalasis (CCh) compared to age-matched controls.

    Methods: This cross-sectional, controlled study included 27 eyes of 27 patients with CCh and 16 eyes of 16 age-matched controls. A biopsy of the bulbar conjunctiva was performed along the temporal lower lid margin before cataract surgery in both groups. Read More

    Interventional Treatment of Pulmonary Lymphatic Anomalies.
    Tech Vasc Interv Radiol 2016 Dec 8;19(4):299-304. Epub 2016 Oct 8.
    CHOP/HUP Center for Lymphatic Imaging and Interventions, Children's Hospital of Philadelphia, Penn Medicine: Hospital of University of Pennsylvania, Philadelphia, PA. Electronic address:
    Pulmonary lymphatic diseases have been recognized for many years and have been referred as pulmonary lymphangiectasia, pulmonary lymphangiomatosis, plastic bronchitis, and idiopathic chylothorax or chylopericardium. The lymphatic etiology of these conditions has been determined by detection of cystic lymphatic structures on biopsy or postmortem examination. Development of new imaging techniques such as dynamic contrast-enhanced magnetic resonance lymphangiography has allowed better understanding of pathophysiology of these conditions. Read More

    Deep Vein Thrombosis as Initial Manifestation of Whipple Disease.
    Case Rep Gastroenterol 2016 Sep-Dec;10(3):640-645. Epub 2016 Nov 7.
    Universidade Federal da Paraíba, João Pessoa, Brazil.
    Introduction: Wipple disease (WD) is a rare chronic disease caused by the bacillus Tropheryma whipplei. Constitutive, rheumatologic, gastrointestinal, cardiac, cerebral, lymphatic, cutaneous, and ophthalmological signs are possible systemic symptoms. However, thrombotic manifestations are rarely described as "stroke-like syndrome" or arterial thrombosis. Read More

    Marginal Zone Lymphoma Complicated by Protein Losing Enteropathy.
    Case Rep Hematol 2016 9;2016:9351408. Epub 2016 Nov 9.
    Department of Gastroenterology and Hepatology, University Hospital Zurich, Zurich University, Zurich, Switzerland.
    Protein losing enteropathy (PLE) refers to excessive intestinal protein loss, resulting in hypoalbuminemia. Underlying pathologies include conditions leading to either reduced intestinal barrier or lymphatic congestion. We describe the case of a patient with long-lasting diffuse abdominal problems and PLE. Read More

    [Nephrotic syndrome complicated by chylous ascites in a girl of 2 years and 8 months old].
    Arch Pediatr 2017 Jan 21;24(1):24-27. Epub 2016 Nov 21.
    Service de pédiatrie nourrissons, CHU de Brazzaville, Brazzaville, Congo; Faculté des sciences de la santé, université Marien Ngouabi, Brazzaville, Congo.
    We report on a case of nephrotic syndrome with focal and segmental hyalinosis complicated by chylous ascites in a girl of 2 years and 8 months old. This pure nephrotic syndrome in its early stage was initially treated with intensive steroid treatment at 2mg/kg/day orally for 2 months, followed by a bolus of methylprednisolone. The persistence of proteinuria meant corticosteroid resistance. Read More

    Young patient with generalized lymphangiomatosis: Differentiating the differential.
    Indian J Radiol Imaging 2016 Jul-Sep;26(3):411-415
    Department of Radiotherapy, Christian Medical College, Vellore, Tamil Nadu, India.
    We present the case of a 19-year-old man who was extensively evaluated in multiple centres for long-standing cough, dyspnea, and hemoptysis without a definitive diagnosis. His chest radiograph at presentation showed mediastinal widening, bilateral pleural effusions, and Kerley B lines. Computed tomography of the thorax showed a confluent, fluid-density mediastinal lesion enveloping the mediastinal viscera without any mass effect. Read More

    Diffuse Pulmonary Lymphangiomatosis: MDCT Findings After Direct Lymphangiography.
    AJR Am J Roentgenol 2017 Feb 15;208(2):300-305. Epub 2016 Nov 15.
    1 Department of CT, Beijing Shijitan Hospital, Capital Medical University, Yangfangdian Tieyiyuan Rd No. 10, Haidian District, Beijing 100038, China.
    Objective: The aim of this study was to analyze the findings of MDCT performed after direct lymphangiography in patients with diffuse pulmonary lymphangiomatosis.

    Materials And Methods: Twenty-three patients (13 male and 10 female patients) diagnosed with diffuse pulmonary lymphangiomatosis on the basis of clinical features and findings from imaging, bronchoscopy, and pathologic analysis were retrospectively evaluated. All patients underwent pulmonary MDCT after direct lymphangiography, surgical operation or open lung biopsy, and histopathologic examination. Read More

    Bilateral Renal Lymphangiectasia.
    J Clin Diagn Res 2016 Sep 1;10(9):TD01-TD02. Epub 2016 Sep 1.
    Professor, Department of Nephrology, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases & Research Centre (IKDRC) & Dr.H.L. Trivedi Institute of Transplantation Sciences (ITS) , Gujarat, India .
    Renal Lymphangiectasia (RLM) is very rare benign lymphatic malformation. It can be misdiagnosed for other cystic renal masses, most commonly polycystic kidneys. Though incidentally found in most cases, it may be the cause for hypertension and renal failure in undiagnosed patients. Read More

    Gastrointestinal Lymphorrhea Diagnosed by Exercise Lymphoscintigraphy.
    Clin Nucl Med 2016 Dec;41(12):e520-e521
    From the *Department of Nuclear Medicine, and †Paediatric Department, University Hospital Split, Split, Croatia.
    Lymphoscintigraphy is not considered as a first line diagnostic procedure in abdominal or thoracic lymphorrhea of various origin. We report a patient with lymphangiectasia in whom posttraumatic lymphorrhea was diagnosed by lymphoscintigraphy only after third attempt when we applied pushups exercise with the aim to raise venous pressure and thus provoke lymph backflow in ductus thoracicus and enteric lymphytics. Lymphorrhea was clearly visible in colon ascendens and colon transversum on 9h planar scintigram. Read More

    Surgical Drainage of Lymphangiectasia Haemorrhagica Conjunctivae.
    Cornea 2017 Jan;36(1):116-118
    *Cole Eye Institute, Cleveland Clinic, Cleveland, OH; and †Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH.
    Purpose: To report a case of nonresolving lymphangiectasia haemorrhagica conjunctivae (LHC) successfully treated with surgical drainage.

    Methods: Retrospective case report.

    Results: A 17-year-old white girl presented with a history of a large red lesion affecting her right eye. Read More

    [Malabsorption is a leading clinical sign of small bowel disease].
    Ter Arkh 2016;88(8):4-9
    Moscow Clinical Research and Practical Center, Moscow Healthcare Department, Moscow, Russia.
    The paper presents a variety of clinical manifestations of malabsorption syndrome (MAS) in celiac disease, collagenous sprue, Whipple's disease, Crohn's disease, intestinal lymphangiectasia, amyloidosis, common variable immune deficiency, and treatment of short bowel syndrome. It shows the specific features of the pathophysiology, diagnosis, and treatment of MAS in small bowel diseases. Read More

    Lymphovenous Anastomosis and Secondary Resection for Noonan Syndrome with Vulvar Lymphangiectasia.
    Plast Reconstr Surg Glob Open 2016 Aug 29;4(8):e1007. Epub 2016 Aug 29.
    Department of Plastic and Reconstructive Surgery, Radboud University Medical Center, Nijmegen, the Netherlands.
    In this case report we describe the use of a 2-stage approach to treat severe recurrent vulvar lymphangiectasia in a patient with Noonan syndrome. First, 3 functional lymphatic vessels were identified and anastomosed to venules in an end-to-end fashion. Then, in a second surgical procedure, the vulvar lesions were resected as much as possible and the vulva was reconstructed. Read More

    Pathological Investigation of Acquired Lymphangiectasia Accompanied by Lower Limb Lymphedema: Lymphocyte Infiltration in the Dermis and Epidermis.
    Lymphat Res Biol 2016 Sep 6;14(3):172-80. Epub 2016 Sep 6.
    2 Department of Plastic and Reconstructive Surgery, The University of Tokyo Hospital , Tokyo, Japan .
    Background: Sometimes acquired lymphangiectasia (lymphangioma circumscriptum), the pathological mechanism of which is unknown, accompanies lymphedema. The purpose of this study was to better understand the pathological changes present in acquired lymphangiectasia.

    Methods And Results: We examined the pathological characteristics of acquired lymphangiectasia with lymphedema among patients treated at the University of Tokyo Hospital from March 2008 to December 2015. Read More

    US-Guided, Direct Puncture Retrograde Thoracic Duct Access, Lymphangiography, and Embolization: Feasibility and Efficacy.
    J Vasc Interv Radiol 2016 Dec 29;27(12):1890-1896. Epub 2016 Aug 29.
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S. Kingshighway Boulevard, Box 8131, St. Louis, MO 63110.
    Purpose: To describe technical details, success rate, and advantages of direct puncture of the thoracic duct (TD) under direct ultrasound (US) guidance at venous insertion in the left neck.

    Materials And Methods: All patients who underwent attempted thoracic duct embolization (TDE) via US-guided retrograde TD access in the left neck were retrospectively reviewed. Indications for lymphangiography were iatrogenic chyle leak, pulmonary lymphangiectasia, and plastic bronchitis. Read More

    Glutamine decreases intestinal mucosal injury in a rat model of intestinal ischemia-reperfusion by downregulating HMGB1 and inflammatory cytokine expression.
    Exp Ther Med 2016 Sep 17;12(3):1367-1372. Epub 2016 Jun 17.
    Department of Anesthesiology, East Hospital, Tongji University School of Medicine, Shanghai 200120, P.R. China.
    Intestinal ischemia-reperfusion (IR) is a common clinical pathophysiological process that is common in severe trauma, major surgery, and in post-resuscitation. Glutamine (Gln) reduces intestinal IR injury, however, its mechanism of action remains to be determined. High mobility group box 1 (HMGB1) protein, nuclear factor-κB (NF-κB), tumor necrosis factor-α (TNF-α), and interleukin-1 (IL-1) are mediators involved in the pathophysiology of intestinal IR injury. Read More

    Duodenal hemangiolymphangioma presenting as chronic anemia: a case report.
    BMC Res Notes 2016 Aug 31;9(1):426. Epub 2016 Aug 31.
    U. Sabana, Bogotá, Colombia.
    Background: Lymphangiomas are a heterogeneous group of congenital vascular malformations characterized by cystic dilation of lymphatic vessels. They can occur at any age, but they are more common during childhood and in cutaneous localizations. Hemangiomas and vascular malformations of the gastrointestinal tract are very uncommon. Read More

    Nonmalignant Adult Thoracic Lymphatic Disorders.
    Clin Chest Med 2016 09;37(3):409-20
    Division of Pulmonary, Critical Care and Sleep Medicine, University of Cincinnati, MSB 6165, 231 Albert Sabin Way, Cincinnati, OH 45267-0564, USA.
    The thoracic lymphatic disorders are a heterogeneous group of uncommon conditions that are associated with thoracic masses, interstitial pulmonary infiltrates, and chylous complications. Accurate diagnosis of the thoracic lymphatic disorders has important implications for the newest approaches to management, including embolization and treatment with antilymphangiogenic drugs. New imaging techniques to characterize lymphatic flow, such as dynamic contrast-enhanced magnetic resonance lymphangiogram, are redefining approaches to disease classification and therapy. Read More

    Disorders of the lymphatic system of the abdomen.
    Clin Radiol 2016 Oct 19;71(10):941-52. Epub 2016 Jul 19.
    Departments of Radiology, Apollo Hospitals, Bannerghatta Road, Bangalore, India.
    The lymphatic system of the abdomen comprises of the cisterna chyli, its major and minor lymphatic tributaries, and lymph nodes. Disorders of the lymphatic system of the abdomen are rarely encountered and consist of primary and secondary types. Abdominal lymphangiomas constitute the majority and have characteristic imaging features. Read More

    Intestinal Lymphangiectasia: Insights on Management and Literature Review.
    Am J Case Rep 2016 Jul 21;17:512-22. Epub 2016 Jul 21.
    Department of Gastroenterology, Aleppo University, Aleppo, Syrian Arab Republic.
    BACKGROUND Intestinal lymphangiectasia (IL) is a rare disease characterized by a dilatation of the intestinal lymphatics and loss of lymph fluid into the gastrointestinal tract leading to hypoproteinemia, edema, lymphocytopenia, hypogammaglobinemia, and immunological abnormalities. Iron, calcium, and other serum components (e.g. Read More

    Expanding the genotypic spectrum of CCBE1 mutations in Hennekam syndrome.
    Am J Med Genet A 2016 Oct 27;170(10):2694-7. Epub 2016 Jun 27.
    Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.
    Hennekam lymphangiectasia-lymphedema syndrome is an autosomal recessive disorder, with 25% of patients having mutations in CCBE1. We identified a family with two brothers presenting with primary lymphedema, and performed exome sequencing to determine the cause of their disease. Analysis of four family members showed that both affected brothers had the same rare compound heterozygous mutations in CCBE1. Read More

    Hyperplasia, de novo lymphangiogenesis, and lymphatic regression in mice with tissue-specific, inducible overexpression of murine VEGF-D.
    Am J Physiol Heart Circ Physiol 2016 Aug 24;311(2):H384-94. Epub 2016 Jun 24.
    Division of Lymphatic Biology, Department of Medical Physiology, Texas A&M Health Science Center School of Medicine, College Station, Texas; Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas; and
    Lymphatic vessels modulate tissue fluid balance and inflammation and provide a conduit for endocrine and lipid transport. The growth of new lymphatic vessels in the adult, lymphangiogenesis, is predominantly mediated through vascular endothelial growth factor receptor-3 (VEGFR-3) signaling. We took advantage of the unique binding of murine VEGF-D specifically to VEGFR-3 and generated mice capable of inducible, tissue-specific expression of murine VEGF-D under a tightly-controlled tetracycline response element (TRE) promoter to stimulate adult tissue lymphangiogenesis. Read More

    Successful Treatment of Acquired Balanic Lymphangiectasia Following Circumcision Using 2,940-nm Erbium-Doped Yttrium Aluminium Garnet Laser.
    Dermatol Surg 2016 Aug;42(8):1017-8
    Department of Dermatology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China Department of Radiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China Department of Dermatology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.

    Successful Treatment of Conjunctival Lymphangiectasia With Subconjunctival Injection of Bevacizumab.
    Cornea 2016 Oct;35(10):1375-7
    *Department of Ophthalmology, Prince of Wales Hospital, Sydney, Australia; †Hispath, Specialist Pathologists, Sydney, Australia; and ‡Ophthalmic Surgeons, Sydney, Australia.
    Purpose: To report a novel intervention for the treatment of conjunctival lymphangiectasia-subconjunctival injection of bevacizumab.

    Methods: A 53-year-old white male presented with a 3-month history of right ocular discomfort and redness unresponsive to conventional topical treatment of lubricants and steroids. A clinical diagnosis of conjunctival lymphangiectasia was confirmed by biopsy. Read More

    Protein-losing enteropathy with intestinal lymphangiectasia in skeletal dysplasia with Lys650Met mutation.
    Am J Med Genet A 2016 Nov 23;170(11):2993-2997. Epub 2016 May 23.
    Division of Anatomic and Molecular Pathology, Department of Pathology and Immunology, St. Louis Children's Hospital, Washington University Medical Center, St. Louis, Missouri.
    Protein-losing enteropathy is a primary or secondary manifestation of a group of conditions, and etiologies which are broadly divisible into those with mucosal injury on the basis of inflammatory and ulcerative conditions, mucosal injury without erosions or ulcerations, and lymphatic abnormalities. We describe the first case of protein-losing enteropathy in a pediatric patient, with severe skeletal dysplasia consistent with thanatophoric dysplasia type I and DNA analysis that revealed a c.1949A>T (p. Read More

    [Clinical analysis of two cases with diffuse pulmonary lymphatic disease].
    Zhonghua Er Ke Za Zhi 2016 May;54(5):360-4
    Department of Respiratory Diseases, Beijing Children's Hospital Affiliated to Capital Medical University, Beijing 100045, China.
    Objective: To analyze the clinical characteristics and diagnosis of 2 cases with diffuse pulmonary lymphatic disease.

    Method: Clinical manifestations of the children were retrospectively analyzed. Two patients were both from Beijing Children Hospital in 2013 and 2014. Read More

    Ten-Year Experience With Bowel Transplantation at Seoul St. Mary's Hospital.
    Transplant Proc 2016 Mar;48(2):473-8
    Department of Surgery, Intestinal Transplantation and Rehabilitation Unit, Organ Transplantation Center, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea. Electronic address:
    A retrospective review of intestinal transplantation (ITx) at Seoul St. Mary's Hospital was made by collecting clinical data over the past 10 years. Fifteen consecutive cases from 2004 were analyzed. Read More

    Successful therapy for protein-losing enteropathy caused by chronic neuronopathic Gaucher disease.
    Mol Genet Metab Rep 2016 Mar 29;6:13-5. Epub 2015 Dec 29.
    Department of Pediatrics and Child Health, University of Manitoba, Canada; Department of Biochemistry and Medical Genetics, University of Manitoba, Canada.
    Gaucher disease (OMIM #230800) is caused by β-glucosidase deficiency and primarily involves the mononuclear phagocyte system (also called Reticuloendothelial System or Macrophage System). The disease is classified into three main phenotypes based on the presence or absence of neurological manifestations: non-neuronopathic (type 1), acute neuronopathic (type 2) and chronic neuronopathic (type 3). Typical manifestations include hepatosplenomegaly, skeletal deformities, hematological abnormalities, interstitial lung fibrosis and neurodegeneration in neuronopathic cases. Read More

    Acquired Lymphangiectasia of the Breast After Breast Conserving Surgery.
    Indian J Surg 2015 Dec 25;77(Suppl 3):1421-2. Epub 2015 Jan 25.
    Department of General Surgery, Turgut Özal University, Ankara, Turkey.
    Lymphangiectasia is characterized by vesicular dilation of lymphatic vessels and is generally a complication of radiotherapy or surgery of various malignant tumors such as breast and cervical cancers. Although it is not a precancerous disease, correct diagnosis is important to rule out Stewart-Treves syndrome which is defined as lymphangiosarcoma that develops in long-standing chronic postmastectomy lymphedema. Observation alone or many therapeutic options including cryosurgery, electrocauterization, sclerotherapy, and excision have been widely used in the management. Read More

    Acquired lymphangiectasia (lymphangioma circumscriptum) of the vulva: Clinicopathologic study of 11 patients from a single institution and 67 from the literature.
    Int J Dermatol 2016 Sep 9;55(9):e482-7. Epub 2016 Mar 9.
    Department of Dermatology, Mayo Clinic, Rochester, MN, USA.
    Background: Acquired lymphangiectasia of the vulva (ALV) is a rare condition thought to be secondary to pelvic lymphatic obstruction. Although benign, this entity often occurs after previous malignancy and can be confused with conditions such as genital warts. We sought to clarify the clinicopathologic features of ALV by studying affected patients from our institution and from the existing literature. Read More

    Primary Intestinal Lymphangiectasia Manifested as Unusual Edemas and Effusions: A Case Report.
    Medicine (Baltimore) 2016 Mar;95(10):e2849
    From the Department of Cardiology, Department of Respiratory Medicine, Department of Pathology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
    Primary intestinal lymphangiectasia (PIL) is a rare disorder of unknown etiology characterized by diffuse or localized dilation and eventual rupture of the enteric lymphatic vessels in mucosa, submucosa, and/or subserosa. Lymph, rich in all kinds of proteins and lymphocytes, leaks into the gastrointestinal tract via the affected lymphatic vessels causing hypoproteinemia and lymphopenia. The main symptom is variable degrees of pitting edemas of bilateral lower limbs. Read More

    Secondary hypogammaglobulinemia in Waldmann's disease treated with subcutaneous immunoglobulins.
    Eur Ann Allergy Clin Immunol 2016 Mar;48(2):55-7
    Department of Medicine, University of Verona, Verona, Italy.
    Primary intestinal lymphangiectasia (PIL) is rare disorder characterized by congenital malformation or obstruction of intestinal lymphatic drainage; it is responsible for protein losing enteropathy leading to lymphopenia, hypoalbuminemia and hypogammaglobulinemia. A low-fat diet associated with medium-chain triglyceride supplementation is the cornerstone of PIL management. The administration of intravenous immunoglobulins does not always lead to satisfactory plasma levels and therefore the replacement therapy with immunoglobulins is controversial. Read More

    Everolimus for Primary Intestinal Lymphangiectasia With Protein-Losing Enteropathy.
    Pediatrics 2016 Mar 16;137(3):e20152562. Epub 2016 Feb 16.
    Departments of Pediatrics.
    Primary intestinal lymphangiectasia (PIL), also known as Waldmann's disease, is an exudative enteropathy resulting from morphologic abnormalities in the intestinal lymphatics. In this article, we describe a 12-year-old boy with PIL that led to protein-losing enteropathy characterized by diarrhea, hypoalbuminemia associated with edema (serum albumin level: 1.0 g/dL), and hypogammaglobulinemia (serum IgG level: 144 mg/dL). Read More

    Congenital generalized lymphangiectasia: a rare developmental disorder for non-immune fetal hydrops.
    Autops Case Rep 2015 Oct-Dec;5(4):27-33. Epub 2015 Dec 30.
    Pediatrics Department - Faculty of Medicine - University of São Paulo, São Paulo/SP - Brazil .
    Firstly described by Rudolf Virchow in the 19th century, congenital generalized lymphangiectasia is a rare entity characterized by dilation of lymphatic vessels, and was recently classified in primary or secondary lymphangiectasia. Generalized forms may be diagnosed during pre-natal follow-up with ultrasound examination, and, depending on its severity, the newborn outcome is very poor. The authors report the case of a female newborn with a previous diagnosis of fetal hydropsy who was born after a full-term gestation with respiratory failure due to bilateral voluminous pleural effusion and ascites. Read More

    The role of capsule endoscopy in etiological diagnosis and management of obscure gastrointestinal bleeding.
    Intest Res 2016 Jan 26;14(1):69-74. Epub 2016 Jan 26.
    Department of Gastroenterology, Lokmanya Tilak Municipal Medical College & Lokmanya Tilak Municipal General Hospital, Mumbai, India.
    Background/aims: To investigate the various etiologies, yields, and effects of capsule endoscopy (CE) on management and complications, along with follow up of patients with obscure gastrointestinal (GI) bleeding.

    Methods: The study group of patients included those having obscure, overt, or occult GI bleeding. The findings were categorized as (A) obvious/definitive, (B) equivocal, or (C) negative. Read More

    Disorders associated with malabsorption of iron: A critical review.
    Pak J Med Sci 2015 Nov-Dec;31(6):1549-53
    Khansa Qamar, M.Phil. (Hematology). Baqai Institute of Hematology, Baqai Medical University, Karachi, Pakistan.
    Malabsorption is a disorder of the gastrointestinal tract that leads to defective digestion, absorption and transport of important nutrients across the intestinal wall. Small intestine is the major site where most of the nutrients are absorbed. There are three main mechanisms of malabsorption; premucosal, mucosal and postmucosal. Read More

    Renal Lymphangiectasia: A Curious Cause of Pleural Effusion.
    Tanaffos 2015 ;14(3):213-6
    Telemedicine Research Center, NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
    Renal lymphangiectasia is a disorder of the lymphatic system of the kidneys, which can be congenital or acquired. Although the exact etiology remains unknown, an obstructive process resulting from several causes, including infection, inflammation or malignant infiltration, has been suggested to be responsible for the acquired form. This disorder may be associated with several pathologies. Read More

    Intestinal lymphangiectasia in children. A favorable response to dietary modifications.
    Saudi Med J 2016 Feb;37(2):199-204
    Department of Pediatrics, Salmaniya Medical Complex, Manama, Bahrain. E-mail.
    Intestinal lymphangiectasia (IL) is a rare disease characterized by dilatation of intestinal lymphatics. It can be classified as primary or secondary according to the underlying etiology. The clinical presentations of IL are pitting edema, chylous ascites, pleural effusion, acute appendicitis, diarrhea, lymphocytopenia, malabsorption, and intestinal obstruction. Read More

    Ocular Adnexal Acne Agminata: Histopathological and Clinical Case Series.
    Ophthal Plast Reconstr Surg 2016 Mar-Apr;32(2):150-3
    *Department of Ophthalmology, Albany Medical College, Albany, New York; †Division of Dermatology and Dermatopathology, Department of Pathology, Albany Medical College, Albany, New York; and ‡Ophthalmic Plastic Surgery, Department of Ophthalmology, Albany Medical College, Lions Eye Institute, Slingerlands, New York, U.S.A.
    Purpose: Acne agminata has only been rarely reported in the ocular adnexa. This study was undertaken to identify histopathological, clinical, and management features of this disorder.

    Methods: A computerized database was utilized to identify cases of ocular adnexal acne agminata. Read More

    Noonan Syndrome Complicated by Primary Pulmonary Lymphangiectasia.
    Neonatal Netw 2015 ;34(2):117-25
    Noonan syndrome is a genetic disorder that has several features common to other conditions, making diagnosis a challenge. This column summarizes the case of a neonate with an atypical presentation of Noonan syndrome involving a fatal type of lymphangiectasia resulting in persistent pleural effusions. Radiographic features of this condition are presented along with the complexities of diagnosis and treatment. Read More

    A 42-Year-Old Woman With Abnormal Chest CT Scan and Chylous Ascites.
    Chest 2016 Jan 6;149(1):e25-8. Epub 2016 Jan 6.
    Department of Pulmonary and Critical Care Medicine, Case Western Reserve University, Louis Stokes Cleveland Department of Veterans Affair Medical Center, Cleveland OH. Electronic address:
    A 42-year-old white woman presented to the pulmonary clinic for evaluation of abnormal chest imaging. Twenty years prior to presentation, she was noted to have an abnormal chest radiograph during a routine preemployment evaluation. A subsequent bronchoscopy was nondiagnostic. Read More

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