2,506 results match your criteria Lymph Node Dissection Retroperitoneal


Preservation of Ejaculatory Function After Postchemotherapy Retroperitoneal Lymph Node Dissection (PC-RPLND) in Patients With Testicular Cancer: Template vs. Bilateral Resection.

Front Surg 2018 17;5:80. Epub 2019 Jan 17.

Department of Urology, Medical Faculty, University of Duesseldorf, Duesseldorf, Germany.

Post-chemotherapy retroperitoneal lymph node dissection (PC-RPLND) plays a crucial role in treatment of metastatic non-seminomatous germ cell cancer. To evaluate the functional outcome regarding the preservation of ejaculatory function comparing a bilateral vs. unilateral template resection in PC-RPLND patients. Read More

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http://dx.doi.org/10.3389/fsurg.2018.00080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345078PMC
January 2019
1 Read

[A Case of Retroperitoneal Metastasis of Breast Cancer with Effective Insertion of Plural Stents].

Gan To Kagaku Ryoho 2018 Dec;45(13):2220-2222

Dept. of Breast Endocrinological Surgery, Tokyo Women's Medical University Yachiyo Medical Center.

A 61-year-old woman was referred to our hospital because of epigastric pain during chemotherapy for breast cancer recurrence. She was diagnosed with left breast cancer and underwent mastectomy with axillary lymph node dissection 13 years previously. The postoperative pathological examination result was luminal invasive lobular carcinoma. Read More

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December 2018

[Primary Undifferentiated Pleomorphic Sarcoma of the Ileum-A Case Report].

Gan To Kagaku Ryoho 2018 Dec;45(13):2141-2143

Dept. of Surgery, The Nippon Dental University, School of Life Dentistry.

Undifferentiated pleomorphic sarcoma(UPS)of the small intestine is extremely rare and has a poor prognosis. We encountered a case of primary UPS of the ileum without metastatic lesions. The patient was a 44-year-old man who presented with the chief complaint of lower abdominal pain for 9 months. Read More

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December 2018
1 Read

Management of Residual Mass in Germ Cell Tumors After Chemotherapy.

Curr Oncol Rep 2019 Jan 21;21(1). Epub 2019 Jan 21.

Department of Urology, Indiana University School of Medicine, 535 Barnhill Dr., Indianapolis, IN, 46202, USA.

Purpose Of Review: The purpose of this review is to educate medical oncologists on the management of patients with residual germ cell tumors and the role of surgical resection after platinum-based chemotherapy.

Recent Findings: Patients with non-seminomatous testicular cancer and residual enlarged retroperitoneal lymph nodes > 1 cm following induction chemotherapy with normal tumor markers should undergo a post-chemotherapy retroperitoneal lymph node dissection. All patients with primary mediastinal non-seminoma should undergo surgical resection of the mediastinal mass post-chemotherapy. Read More

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http://dx.doi.org/10.1007/s11912-019-0758-6DOI Listing
January 2019
2 Reads

[RETROPERITONEAL LIPOSARCOMA WITH MULTIPLE RECURRENCE OF LUNG METASTASES TREATED BY MULTIMODAL THERAPY CENTERING ON THE OPERATION: A CASE REPORT].

Nihon Hinyokika Gakkai Zasshi 2018 ;109(1):25-29

Department of Urology, Kanagawa Cancer Center.

A 34-year-old man presented with scrotal pain and slight fever. The scrotal pain was improved by the treatment of antibiotics, but the slight fever remained and an abdominal protuberance appeared. Computed tomography showed a 22 cm abdominal tumor with lipid density. Read More

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http://dx.doi.org/10.5980/jpnjurol.109.25DOI Listing
February 2019
1 Read

Therapeutic supine robotic retroperitoneal lymph node dissection for post-chemotherapy residual masses in testicular cancer: technique and outcome analysis of initial experience.

J Robot Surg 2019 Jan 17. Epub 2019 Jan 17.

Max Institute of Cancer Care, New Delhi, India.

Retroperitoneal lymph node dissection (RPLND) is a therapeutic standard of care for post-chemotherapy residual masses in testicular cancer. While a robotic approach to this procedure has the potential of decreasing the morbidity associated with this major endeavour, it is often criticised for its inability to provide a bilateral complete template resection without redocking and repositioning the patient. Herein, we present the technique and initial outcomes of a supine approach to Robotic RPLND (R-RPLND) using the da Vinci Xi system, which obviates the need for repositioning or redocking for a bilateral full template resection. Read More

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http://dx.doi.org/10.1007/s11701-018-00903-0DOI Listing
January 2019

Endoscopic trans-esophageal submucosal tunneling surgery: A new therapeutic approach for diseases located around the aorta ventralis.

World J Gastroenterol 2019 Jan;25(1):85-94

Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Beijing 100853, China.

Aim: To assess the efficiency of endoscopic trans-esophageal submucosal tunneling surgery (EESTS) technique for diseases located around the aorta ventralis.

Methods: Nine pigs were assigned to EESTs. The procedures were as follows: First, a long esophageal submucosal tunnel was established. Read More

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http://dx.doi.org/10.3748/wjg.v25.i1.85DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328960PMC
January 2019
2 Reads

Considerations When Treating Patients with Good-risk Germ Cell Tumors.

Eur Urol Focus 2019 Jan 10. Epub 2019 Jan 10.

Department of Urology, Indiana University, Indiana, IN, USA.

Three cycles of bleomycin, etoposide, and cisplatin or four cycles of etoposide and cisplatin are options for patients with good-risk germ cell tumors. Despite no significant differences in clinical outcomes in a randomized trial, studies suggest variable impact on postchemotherapy retroperitoneal lymph node dissection histology, which may help inform treatment decisions. Read More

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http://dx.doi.org/10.1016/j.euf.2019.01.002DOI Listing
January 2019

Current controversies on the role of lymphadenectomy for testicular cancer for the journal: Urologic Oncology: Seminars and Original Investigations for the special seminars section on the role of lymphadenectomy for urologic cancers.

Urol Oncol 2019 Jan 7. Epub 2019 Jan 7.

Department of Urology, Indiana University School of Medicine, Indianapolis, IN.

The role of surgery in the locoregional management of many solid tumors has long been established. For testicular cancer, the incorporation of lymphadenectomy has played an important part in generating long-term survival outcomes in excess of 90% for germ cell tumor patients. In this review, we address several clinical scenarios in which lymphadenectomy at times is underutilized, and others ill advised. Read More

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http://dx.doi.org/10.1016/j.urolonc.2018.12.021DOI Listing
January 2019
2 Reads

Robotic retroperitoneal lymph node dissection for testicular cancer: feasibility and latest outcomes.

Curr Opin Urol 2019 Mar;29(2):173-179

Swedish Urology Group, Seattle, Washington, USA.

Purpose Of Review: Robotic-assisted laparoscopic retroperitoneal lymph node dissection (R-RPLND) is gaining acceptance as an alternative to open and laparoscopic RPLND for the treatment of testicular cancer. We discuss the current state of R-RPLND and summarize the latest relevant literature regarding the feasibility of this operation.

Recent Findings: R-RPLND has been utilized effectively for both treatment of high-risk, clinical stage I testicular cancer as well as in the postchemotherapy setting. Read More

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http://Insights.ovid.com/crossref?an=00042307-900000000-9913
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http://dx.doi.org/10.1097/MOU.0000000000000582DOI Listing
March 2019
2 Reads

[Clinicopathologic and survival analysis of synchronous primary endometrial and ovarian cancer].

Zhonghua Fu Chan Ke Za Zhi 2018 Dec;53(12):816-822

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.

To demonstrate the clinicopathological characteristics and determine the prognostic factors for women with synchronous primary endometrial and ovarian cancer (SEOC) . A retrospective analysis of 63 pathologically proven cases of SEOC diagnosed in Peking Union Medical College Hospital from January 2000 to May 2018 was carried out. (1) Clinical features: mean age at diagnosis was (48. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-567x.2018.12.004DOI Listing
December 2018
2 Reads

Concurrent primary repair of obturator nerve transection during pelvic lymphadenectomy procedure via laparoscopical approach.

Int J Surg Case Rep 2018 13;53:394-396. Epub 2018 Nov 13.

TC Ministry of Health, Health Sciences University, Gazi Yaşargil Diyarbakır Training and Research Hospital, Obstetrics and Gynecology, Diyarbakir, Turkey. Electronic address:

Introduction: Obturator nerve is barely injured during gynecological surgeries. The risk for obturator nerve injury is increased during pelvic lymphadenectomy procedures of gynecological malignancies. In case of any obturator nerve injury, surgical management involve laparoscopic approaches suchas end-to-end anastomosis in very early period. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.10.081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259042PMC
November 2018
1 Read

L1 Cell Adhesion Molecule (L1CAM) expression in endometrioid endometrial carcinomas: A possible pre-operative surrogate of lymph vascular space invasion.

PLoS One 2018 17;13(12):e0209294. Epub 2018 Dec 17.

Department of Pathology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.

Background: Risk stratification of endometrial carcinomas is primarily based on surgical staging that requires extensive retroperitoneal lymph node dissection. One of the most powerful predictor of lymph node involvement is the lymph vascular space invasion (LVSI). The objective of this study was to determine the potential of L1 Cell Adhesion Molecule (L1CAM) to predict LVSI and its association with other risk factors in endometrioid endometrial carcinomas. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0209294PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296540PMC
December 2018

Benefits of Elective Para-Aortic Radiotherapy for pN1 Prostate Cancer Using Arc Therapy (Intensity-Modulated or Volumetric Modulated Arc Therapy): Protocol for a Nonrandomized Phase II Trial.

JMIR Res Protoc 2018 Dec 13;7(12):e11256. Epub 2018 Dec 13.

Department of Radiation Oncology, University Hospitals Leuven, University of Leuven, Leuven, Belgium.

Background: In patients with prostate cancer (PCa) with histopathologically proven pelvic lymph node (LN) metastasis (pN1) after extended pelvic lymph node dissection (ePLND), multimodality treatment consisting of treatment of the primary tumor and whole pelvic radiotherapy (WPRT) combined with androgen deprivation therapy (ADT) offers promising results, leading to better cause-specific survival rates compared with ADT alone. However, in case more than one pelvic LN is invaded by the tumor, approximately 40% of the patients relapse biochemically and clinically. Clinical relapse is present in the para-aortic LNs (M1a disease) in up to 77% of the relapsing cases. Read More

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https://www.researchprotocols.org/2018/12/e11256/
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http://dx.doi.org/10.2196/11256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315267PMC
December 2018
5 Reads

Nodal Oligorecurrent Prostate Cancer: Anatomic Pattern of Possible Treatment Failure in Relation to Elective Surgical and Radiotherapy Treatment Templates.

Eur Urol 2018 Nov 28. Epub 2018 Nov 28.

Department of Radiation Oncology and Experimental Cancer Research, Ghent University, Ghent, Belgium. Electronic address:

Background: Patients with biochemical recurrence following primary prostate cancer (PCa) treatment often experience relapse in the lymph nodes (LNs). Both salvage LN dissection (sLND) and elective nodal radiotherapy (ENRT) are potential treatment options.

Objective: To describe anatomic patterns of nodal oligorecurrent PCa in relation to different surgical and radiotherapy templates. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03022838183083
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http://dx.doi.org/10.1016/j.eururo.2018.10.044DOI Listing
November 2018
11 Reads

Diagnosis and management of the growing teratoma syndrome: A single-center experience and review of the literature.

Urol Oncol 2018 12 13;36(12):529.e23-529.e30. Epub 2018 Nov 13.

Department of Urology, University Hospital Cologne, Cologne, Germany. Electronic address:

Objectives: To evaluate the diagnostic, surgical as well as oncological outcome of patients with a growing teratoma syndrome.

Material And Methods: We performed a retrospective analysis including 680 patients with advanced nonseminomatous germ cell tumors who underwent a postchemotherapy retroperitoneal lymph node dissection. The peri- and postoperative outcome of 22 patients (3%) that fulfilled the criteria of a growing teratoma syndrome were analyzed: nonseminomatous germ cell tumors with increasing tumor size during or after chemotherapy despite normalized or decreasing tumor markers. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10781439183035
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http://dx.doi.org/10.1016/j.urolonc.2018.09.012DOI Listing
December 2018
17 Reads

Current controversies on the role of retroperitoneal lymphadenectomy for testicular cancer.

Urol Oncol 2019 Mar 13;37(3):209-218. Epub 2018 Nov 13.

Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY. Electronic address:

Retroperitoneal lymph node dissection (RPLND) is an important component of the multimodal treatment which cures most patients diagnosed with testicular germ cell tumors. Considering the high cure rates achieved, research focus in recent years has been directed toward improving quality of life and decreasing long-term treatment related sequelae. Consequently, the role of RPLND has evolved over the past 3 decades in both low-stage and advanced testicular cancer. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10781439183035
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http://dx.doi.org/10.1016/j.urolonc.2018.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379133PMC
March 2019
15 Reads

Patterns of Lymph Node Recurrence in Adrenocortical Carcinoma: Possible Implications for Primary Surgical Treatment.

Ann Surg Oncol 2019 Feb 15;26(2):531-538. Epub 2018 Nov 15.

Department of General, Viszeral, and Thoracic Surgery, Kreisklinik Altötting, Altötting, Germany.

Background: In the surgical treatment of adrenocortical carcinoma (ACC), lymphadenectomy may improve oncologic outcome. However, patterns of metastatic lymphatic spread in ACC are unknown.

Methods: Clinical data of patients included in the European Network for the Study of Adrenal Tumors (ENSAT) registry were retrospectively reviewed. Read More

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http://link.springer.com/10.1245/s10434-018-6999-z
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http://dx.doi.org/10.1245/s10434-018-6999-zDOI Listing
February 2019
10 Reads

Sentinel Node Biopsy in Clinical Stage I Testicular Cancer Enables Early Detection of Occult Metastatic Disease.

BJU Int 2018 Nov 11. Epub 2018 Nov 11.

Department of Oncological Urology, UMC Utrecht Cancer Center, University Medical Center Utrecht, Utrecht, The Netherlands.

Objectives: To report the long-term results of the sentinel node approach in clinical stage I testicular tumour patients in our facility.

Patients And Methods: Analysis of 27 consecutive patients suspected of clinical stage I testicular germ cell tumour and treated with a sentinel node procedure at our tertiary referral centre. Sentinel nodes were identified using lymphoscintigraphy with or without single photo emission computed tomography with computed tomography. Read More

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http://doi.wiley.com/10.1111/bju.14618
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http://dx.doi.org/10.1111/bju.14618DOI Listing
November 2018
12 Reads

Huge mucinous tubular and spindle cell carcinoma of kidney: A rare case report and literature review.

Medicine (Baltimore) 2018 Oct;97(43):e12933

Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.

Rationale: Mucinous tubular and spindle cell carcinoma (MTSCC) is a variant of renal cell carcinoma newly added to the WHO classification in 2004. It is a rare variant of renal cell carcinoma and sometimes it is not easy to distinguish MTSCC from papillary renal cell carcinoma, chromophobe renal cell cancer, etc. The prognosis of MTSCC is favorable after surgical resection. Read More

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http://dx.doi.org/10.1097/MD.0000000000012933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221687PMC
October 2018
4 Reads

Which Patients with Clinically Node-positive Prostate Cancer Should Be Considered for Radical Prostatectomy as Part of Multimodal Treatment? The Impact of Nodal Burden on Long-term Outcomes.

Eur Urol 2018 Nov 5. Epub 2018 Nov 5.

Unit of Urology, Division of Oncology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy; Vita-Salute San Raffaele University, Milan, Italy.

Background: A role for local therapies including radical prostatectomy (RP) in prostate cancer (PCa) patients with clinical lymphadenopathies has been proposed. However, no data are available to identify men who would benefit from RP in this setting.

Objective: To identify predictors of clinical recurrence (CR) in surgically managed PCa patients with clinical lymphadenopathies. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03022838183083
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http://dx.doi.org/10.1016/j.eururo.2018.10.042DOI Listing
November 2018
5 Reads

Castleman disease: Case series of two surgical patients from different ends of the disease spectrum with literature review.

Int J Surg Case Rep 2018 29;53:163-167. Epub 2018 Oct 29.

Goa Medical College, Bambolim, Goa, 403202, India. Electronic address:

Castleman Disease (CD) is a rare, heterogeneous group of hyperimmune lymphoproliferative disorders, not very familiar to surgeons. Unicentric Castleman Disease (UCCD) at one end of the spectrum is a localized disease, with little or no systemic symptoms. It may be an incidental radiological finding or detected while investigating for a symptomatic lymph node mass. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22102612183047
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http://dx.doi.org/10.1016/j.ijscr.2018.10.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216084PMC
October 2018
9 Reads

Primitive neuroectodermal tumor transformation of testicular teratoma.

Urol Ann 2018 Oct-Dec;10(4):413-415

Department of Urology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.

Malignant transformation of teratoma develops in a small subset of testis cancer patients. Primitive neuroectodermal tumor represents a highly malignant component of testicular germ cell tumors. It is a rare clinical entity which is characterized by a high risk of disease progression and death. Read More

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http://dx.doi.org/10.4103/UA.UA_182_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194792PMC
November 2018
6 Reads

[Feasibility analysis on membrane-based right-sided approach of laparoscopic suprapancreatic lymph node dissection for advanced distal gastric cancer].

Zhonghua Wei Chang Wai Ke Za Zhi 2018 Oct;21(10):1142-1147

Department of Gastrointestinal Surgery, Institute of Gastrointestinal Oncology of Xiamen University School of Medicine, Xiamen Municipal Key Laboratory of Gastrointestinal Oncology, Zhongshan Hospital, Xiamen University, Xiamen 361004, China.Email:

Objective: To investigate the feasibility and safety of membrane-based right-sided approach of laparoscopic suprapancreatic lymph node dissection for advanced distal gastric cancer.

Methods: The clinical data of 41 patients with advanced distal gastric cancer who underwent laparoscopic gastrectomy using membrane-based right-sided approach for laparoscopic suprapancreatic lymph node dissection at the Department of Gastrointestinal Surgery, Zhongshan Hospital of Xiamen University from January 2016 to January 2018 were retrospectively analyzed. There were 24 males and 17 females with a mean age of 56. Read More

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October 2018
16 Reads

Is there still a place for retroperitoneal lymph node dissection in clinical stage 1 nonseminomatous testicular germ-cell tumours? A retrospective clinical study.

BMC Urol 2018 Oct 26;18(1):95. Epub 2018 Oct 26.

MVZ Hanse Histologikum, Hamburg, Germany.

Background: Primary retroperitoneal lymph node dissection (RPLND) ultimately lost its role as the standard management of clinical stage (CS) 1 nonseminomatous (NS) testicular germ cell tumours (GCTs) in Europe when the European Germ Cell Cancer Consensus Group released their recommendations in 2008. Current guide-lines recommend surgery only for selected patients but reasons for selection remain rather ill-defined. We evaluated the practice patterns of the management of CS1 patients and looked specifically to the role of RPLND among other standard treatment options. Read More

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https://bmcurol.biomedcentral.com/articles/10.1186/s12894-01
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http://dx.doi.org/10.1186/s12894-018-0412-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204050PMC
October 2018
14 Reads

Delayed Return of Ejaculatory Function in Adolescent Males Treated With Retroperitoneal Lymph Node Dissection and Adjuvant Therapy for Paratesticular Rhabdomyosarcoma.

Urology 2018 Oct 23. Epub 2018 Oct 23.

Department of Urology, Boston Children's Hospital, Boston, MA; Department of Surgery, Harvard Medical School, Boston, MA. Electronic address:

Due to the rarity of the disease, adverse events related to ejaculatory function following the management of paratesticular rhabdomyosarcoma with multimodal therapy in adolescents are rarely discussed. Two patients, age 14 and 15 at time of diagnosis were treated with multimodal therapy with nerve-sparing retroperitoneal lymph node dissection, chemotherapy, and radiotherapy. Each developed ejaculatory dysfunction during the treatment period, which resolved 1 year after completion of all therapies. Read More

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http://dx.doi.org/10.1016/j.urology.2018.10.030DOI Listing
October 2018
2 Reads

Malignant mesothelioma of tunica vaginalis testis: Report of a very rare case with review of the literature.

Arch Ital Urol Androl 2018 Sep 30;90(3):212-214. Epub 2018 Sep 30.

General Hospital of Bolzano, Department of Urology, Bolzano.

Introduction: Mesothelioma of the tunica vaginalis testis is a extremely rare tumor and represents 0.3 to 0.5% of all malignant mesotheliomas. Read More

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https://www.pagepressjournals.org/index.php/aiua/article/vie
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http://dx.doi.org/10.4081/aiua.2018.3.212DOI Listing
September 2018
19 Reads

The Value of Tc-PSMA SPECT/CT-Guided Surgery for Identifying and Locating Lymph Node Metastasis in Prostate Cancer Patients.

Ann Surg Oncol 2019 Feb 15;26(2):653-659. Epub 2018 Oct 15.

Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, China.

Background: This study evaluated the effect of technetium-99m (Tc)-labeled prostate-specific membrane antigen (PSMA)-based image-guided surgery on the oncologic outcomes for patients with primary or recurrent prostate cancer (PCa).

Methods: This study retrospectively analyzed 54 consecutive patients with PCa who underwent Tc-labeled PSMA-based image-guided surgery between January 2016 and September 2017. These patients received a radical prostatectomy (RP) with pelvic lymph node dissection (PLND) or salvage lymph node dissection (sLND). Read More

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http://link.springer.com/10.1245/s10434-018-6805-y
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http://dx.doi.org/10.1245/s10434-018-6805-yDOI Listing
February 2019
15 Reads

Identifying the Optimal Candidate for Salvage Lymph Node Dissection for Nodal Recurrence of Prostate Cancer: Results from a Large, Multi-institutional Analysis.

Eur Urol 2019 01 6;75(1):176-183. Epub 2018 Oct 6.

Division of Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy. Electronic address:

Background: Salvage lymph node dissection (SLND) represents a possible treatment option for prostate cancer patients affected by nodal recurrence after local treatment. However, SLND may be associated with intra- and postoperative complications, and the oncological benefit may be limited to specific groups of patients.

Objective: To identify the optimal candidates for SLND based on preoperative characteristics. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03022838183065
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http://dx.doi.org/10.1016/j.eururo.2018.09.009DOI Listing
January 2019
3 Reads

Low-dose, short course alteplase treatment of submassive pulmonary embolism: a case series from the National Institutes of Health Clinical Center.

Blood Coagul Fibrinolysis 2018 Dec;29(8):701-707

Department of Radiologic Diagnostics, National Institutes of Health Clinical Center, Bethesda, Maryland, USA.

: Guidelines-recommend thrombolytic therapy for pulmonary embolism in patients with severe hemodynamic compromise and low risk of bleeding. Thrombolytics in submassive pulmonary embolism have an unfavorable risk/benefit ratio and remain controversial. Based on our experience with extensive, lower extremity thrombi, nine patients with symptomatic, submassive pulmonary embolisms (five medical, four surgical) were treated with low-dose alteplase (<10 mg/day, infused over 6 h per treatment). Read More

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http://Insights.ovid.com/crossref?an=00001721-900000000-9859
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http://dx.doi.org/10.1097/MBC.0000000000000774DOI Listing
December 2018
13 Reads

Surgical Management of Patients with Advanced Germ Cell Tumors Following Salvage Chemotherapy: Memorial Sloan Kettering Cancer Center (MSKCC) Experience.

Urology 2018 Oct 6. Epub 2018 Oct 6.

Urology Service, Department of Surgery, Sidney Kimmel Center for Prostate and Urological Cancers, Memorial Sloan Kettering Cancer Center, New York, NY.

Objective: To characterize clinical and pathologic outcomes of cisplatin-refractory or relapsed germ cell tumor (GCT) patients who underwent retroperitoneal lymph node dissection (RPLND) following salvage chemotherapy with either conventional or high dose regimens.

Methods: Data were reviewed to identify all patients treated with TIP or TICE salvage chemotherapy between 1994 and 2011(n = 184) at our institution. We report clinicopathologic and outcomes data on 131 patients who were further managed with surgical resection. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00904295183106
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http://dx.doi.org/10.1016/j.urology.2018.09.024DOI Listing
October 2018
18 Reads

Efficacy of a Fibrin Sealant (Tissucol Duo) for the Preventionof Lymphocele after Laparoscopic Pelvic Lymphadenectomy:A Randomized Controlled Trial.

J Minim Invasive Gynecol 2018 Oct 5. Epub 2018 Oct 5.

Gynecologic Oncology Unit, Department of Gynaecology and Obstetrics, Hospital Universitario Donostia, San Sebastián, Spain (all authors).

Study Objective: To assess the efficacy of Tissucol Duo (Baxter AG, Vienna, Austria) fibrin sealant in decreasing the incidence of lymphocele (LC) after pelvic laparoscopic lymph node dissection using harmonic shears.

Design: Randomized controlled trial (Canadian Task Force classification level I).

Setting: Tertiary referral and educational center. Read More

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http://dx.doi.org/10.1016/j.jmig.2018.10.002DOI Listing
October 2018
10 Reads

Ex vivo indocyanine green fluorescence imaging for the detection of lymph node involvement in advanced-stage ovarian cancer.

J Surg Oncol 2018 Dec 7;118(7):1163-1169. Epub 2018 Oct 7.

Department of Surgery, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.

Background And Objectives: The aim of this study was to evaluate the role of indocyanine green (ICG) fluorescence imaging (FI) for the ex vivo detection of metastatic lymph nodes (LNs) in advanced stage ovarian cancer (AOC).

Methods: Paraffin-embedded LNs from patients included in a previous ICG-FI study (Protocol NCT01834469) were further assessed for fluorescence. Intravenous injection of ICG was delivered intraoperatively. Read More

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http://doi.wiley.com/10.1002/jso.25263
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http://dx.doi.org/10.1002/jso.25263DOI Listing
December 2018
3 Reads

Can systematic lymphadenectomy be omitted for low-risk endometrial cancer?

J Med Invest 2018 ;65(3.4):221-224

Tokushima University Hospital.

The objective of this study was to identify pathological indicators that could be used to identify a subgroup of patients with apparent stage I endometrial cancer who do require retroperitoneal lymphadenectomy. 188 T1 endometrial cancer patients underwent primary surgery at Tokushima University Hospital. We retrospectively evaluated their clinical records and histopathological factors. Read More

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http://dx.doi.org/10.2152/jmi.65.221DOI Listing
January 2019

[Laparoscopic Surgery for isolated lymph nodes recurrence in gynecology. Experience in Argentina.]

Rev Fac Cien Med Univ Nac Cordoba 2018 06 10;75(2):72-81. Epub 2018 Jun 10.

Hospital Italiano de Buenos Aires, Argentina.

Objectives: to describe the perioperative and oncological outcomes of a serie of cases treated with laparoscopic surgery for isolated nodal metastasis of gynecologic malignancies at the Gynecology Service of Hospital Italiano de Buenos Aires and conduct a literature review on the surgical treatment provided to patients with this condition.

Methods: A search was conducted in the surgery records of the Gynecology Service of Hospital Italiano of patients who underwent laparoscopic cytoreductive surgery for isolated nodal recurrence of a gynecologic primary tumor in the period 2009-2015. The medical records were reviewed and data on the patients’ characteristics, the tumor, the surgery and its complications were collected and analyzed. Read More

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http://dx.doi.org/10.31053/1853.0605.v75.n2.17097DOI Listing
June 2018
3 Reads

[Safety and feasibility of the combined medial and caudal approach in laparoscopic D3 lymphadenectomy plus complete mesocolic excision for right hemicolectomy in the treatment of right hemicolon cancer complicated with incomplete ileus].

Zhonghua Wei Chang Wai Ke Za Zhi 2018 Sep;21(9):1039-1044

Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China

Objective: To explore the safety and feasibility of the combined medial and caudal approach in laparoscopic D3 lymphadenectomy plus complete mesocolic excision(CME) for right hemicolectomy in the treatment of right hemicolon cancer complicated with incomplete ileus.

Methods: Clinical data of 65 patients with incomplete obstructive right-sided colon cancer (T1 to 4M0) diagnosed by abdominal CT enhanced scan or MRI and/or electric colonscope undergoing laparoscopic right hemicolectomy (D3 lymphadenectomy + CME) at Department of Emergency Medicine and Department of Gastrointestinal Surgery from June 2014 to June 2017 were retrospectively analyzed. Among them, 33 patients received the combined medial and caudal approach (combined medial and caudal approach group) and the other 32 patients received the cephalo medial-to-lateral approach (cephalo medial-to-lateral approach group). Read More

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September 2018
3 Reads

Late Retroperitoneal Hematoma with Abscess Formation Following Laparoscopic Staging of Endometrial Cancer.

Gynecol Minim Invasive Ther 2018 Jan-Mar;7(1):31-32. Epub 2018 Feb 16.

Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital at Linkou and Chang Gung University College of Medicine, Kwei-Shan, Taoyuan, Taiwan.

Herein, we report a case of a 63-year-old, nonobese, woman who underwent laparoscopic surgical staging for endometrial cancer with pelvic and para-aortic lymph node dissection. After being discharged, the patient presented to the emergency department with fever and abdominal pain, 1 week after the procedure. Abdominal tenderness, fever, and anemia were the key clinical and laboratory findings. Read More

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http://dx.doi.org/10.4103/GMIT.GMIT_3_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135148PMC
February 2018
2 Reads

Is 11C-choline Positron Emission Tomography/Computed Tomography Accurate to Detect Nodal Relapses of Prostate Cancer After Biochemical Recurrence? A Multicentric Study Based on Pathologic Confirmation from Salvage Lymphadenectomy.

Eur Urol Focus 2018 03 24;4(2):288-293. Epub 2015 Dec 24.

Department of Urology, University of Turin, Turin, Italy. Electronic address:

Background: A 11C-choline positron emission tomography/computed tomography (PET/CT) scan is used for restaging prostate cancer (PCa) patients with biochemical recurrence (BCR). Only a few reports have focused on the correlation between PET/CT and nodal relapse location at pathologic examination.

Objective: To assess the accuracy of PET/CT in predicting the site of nodal relapses in patients undergoing pelvic and/or retroperitoneal salvage lymph node dissection (sLND). Read More

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http://dx.doi.org/10.1016/j.euf.2015.12.004DOI Listing
March 2018
2 Reads

Clinical and Radiographic Predictors of Great Vessel Resection or Reconstruction During Retroperitoneal Lymph Node Dissection for Testicular Cancer.

Urology 2019 Jan 1;123:186-190. Epub 2018 Sep 1.

University of Chicago, Department of Surgery, Section of Urology, Chicago, IL.

Objective: To evaluate whether specific clinical or radiographic factors predict inferior vena cava (IVC) or abdominal aortic (AA) resection or reconstruction (RoR) at the time of postchemotherapy retroperitoneal lymph node dissection (RPLND) for germ cell tumors of the testicle.

Materials And Methods: Two hundred seventy-seven patients undergoing postchemotherapy RPLND at two institutions between 2005 and 2015 were identified. Preoperative imaging was reviewed with radiologists blinded to operative details. Read More

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http://dx.doi.org/10.1016/j.urology.2018.08.028DOI Listing
January 2019
11 Reads

Modern Management of Testicular Cancer.

Cancer Treat Res 2018 ;175:273-308

University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA.

Testicular cancer is a rare urological malignancy with high cure rate. The development of highly effective systemic treatment regimens along with advances in surgical treatment of advanced disease has led to continued improvement in outcomes. Patients with testicular cancer who are treated following the treatment guideline mostly achieved high quality of life and long-term survival. Read More

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http://link.springer.com/10.1007/978-3-319-93339-9_13
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http://dx.doi.org/10.1007/978-3-319-93339-9_13DOI Listing
January 2018
21 Reads

Risk of Bleomycin-Related Pulmonary Toxicities and Operative Morbidity After Postchemotherapy Retroperitoneal Lymph Node Dissection in Patients With Good-Risk Germ Cell Tumors.

J Clin Oncol 2018 Oct 29;36(29):2950-2954. Epub 2018 Aug 29.

All authors: Indiana University School of Medicine, Indianapolis, IN.

Purpose: Three cycles of bleomycin, etoposide, and cisplatin (BEP × 3) or four cycles of etoposide and cisplatin (EP × 4) are first-line chemotherapy regimens for men with International Germ Cell Cancer Collaborative Group (IGCCCG) good-risk germ cell tumors (GCTs). We determined whether inclusion of bleomycin affected pulmonary and operative morbidity after postchemotherapy retroperitoneal lymph node dissection (PC-RPLND).

Patients And Methods: We queried our database to identify IGCCCG good-risk patients who received BEP × 3 or EP × 4 induction chemotherapy before PC-RPLND from 2006 to 2016. Read More

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http://dx.doi.org/10.1200/JCO.18.00431DOI Listing
October 2018
12 Reads

Expanding the indications of robotic surgery in urology: A systematic review of the literature.

Arab J Urol 2018 Sep 7;16(3):270-284. Epub 2018 Aug 7.

Bristol Urological Institute, Southmead Hospital, Bristol, UK.

Objectives: To evaluate the recent developments in robotic urological surgery, as the introduction of robotic technology has overcome many of the difficulties of pure laparoscopic surgery enabling surgeons to perform complex minimally invasive procedures with a shorter learning curve. Robot-assisted surgery (RAS) is now offered as the standard for various surgical procedures across multiple specialities.

Methods: A systematic search of MEDLINE, PubMed and EMBASE databases was performed to identify studies evaluating robot-assisted simple prostatectomy, salvage radical prostatectomy, surgery for urolithiasis, distal ureteric reconstruction, retroperitoneal lymph node dissection, augmentation ileocystoplasty, and artificial urinary sphincter insertion. Read More

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http://dx.doi.org/10.1016/j.aju.2018.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105341PMC
September 2018
4 Reads

[Minimal fat renalangiomyolipoma with multiple lymph nodes enlargement and postoperative refractory lymphatic fistula: a case report and literature review].

Beijing Da Xue Xue Bao Yi Xue Ban 2018 Aug;50(4):717-721

Department of Urology, Peking University People's Hospital, Beijing 100044, China.

Renal angiomyolipoma (AML) is a common benign tumor in the urinary system, mainly composed of adipose tissue, blood vessels and muscle tissue. Renal AML is sporadic in most of patients, while a few are associated with tuberous sclerosis. Classical renal AML occurs predominantly in middle-aged females. Read More

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August 2018
19 Reads

The Use of CT-Guided Marking for the Laparoscopic Resection of a Solitary Retroperitoneal Metastasis of Colon Cancer.

J Endourol Case Rep 2018 1;4(1):120-123. Epub 2018 Aug 1.

Division of Urology, Kansai Rosai Hospital, Amagasaki, Japan.

CT-guided marking technique is rarely used in abdominal or urologic surgery. We developed and performed a marking technique for a small tumor, undetectable by ultrasound, using CT guidance before laparoscopic resection of the tumor. A 73-year-old woman with a history of breast cancer underwent right colectomy with D3 lymph node dissection for ascending colon cancer. Read More

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http://dx.doi.org/10.1089/cren.2018.0049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080126PMC
August 2018
4 Reads

Successful retroperitoneal lymphadenectomy for double inferior vena cava with preoperative assessment using contrast-enhanced and three-dimensional computed tomography.

Gynecol Oncol 2018 10 4;151(1):180-181. Epub 2018 Aug 4.

Department of Reproductive Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.

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http://dx.doi.org/10.1016/j.ygyno.2018.08.001DOI Listing
October 2018

Use of 18F-FDG-PET/CT for Retroperitoneal/Intra-Abdominal Soft Tissue Sarcomas.

Contrast Media Mol Imaging 2018 2;2018:2601281. Epub 2018 Jul 2.

Sarcoma Center, Peking University Cancer Hospital & Institute, Beijing, China.

Rationale: To assess the diagnostic value of 18F-FDG-PET/CT for different retroperitoneal soft tissue sarcomas (STS) and other similar tumors. To analyze the predictive value of 18F-FDG-PET/CT for histological grade and main prognostic factors.

Methods: 195 patients with 44 different diseases have been included. Read More

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http://dx.doi.org/10.1155/2018/2601281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051286PMC
July 2018
8 Reads

[A Case of Giant Testicular Tumor with Pelvic and Inguinal Lymph Nodes Metastasis].

Hinyokika Kiyo 2018 Jun;64(6):277-281

The Department of Urology, Wakayama Medical University.

A 51-year-old man visited our hospital since he had noticed remarkable increase in size of left scrotal contents. Computed tomography revealed left testicular swelling, retroperitoneal, pelvic and left inguinal lymph nodes. Serum testicular tumor markers (α fetoprotein, β-human chorionic gonadotropin, lactate dehydrogenase) were elevated. Read More

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http://dx.doi.org/10.14989/ActaUrolJap_64_6_277DOI Listing
June 2018
16 Reads

Performance of In-labelled PSMA ligand in patients with nodal metastatic prostate cancer: correlation between tracer uptake and histopathology from lymphadenectomy.

Eur J Nucl Med Mol Imaging 2018 11 30;45(12):2062-2070. Epub 2018 Jul 30.

Department of Urology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Purpose: Intraoperative identification of lymph node (LN) metastases (LNM) detected on preoperative PSMA PET/CT may be facilitated by PSMA radioguided surgery with the use of a gamma probe. We evaluated the uptake of In-labelled PSMA ligand DKFZ-617 (referred to as In-PSMA-617) in unaffected LN and LNM at the level of single LN.

Methods: Six patients with prostate cancer (PCa) with suspicion of LNM on preoperative PSMA PET/CT underwent In-PSMA-617-guided lymphadenectomy (LA; four salvage LA and two primary LA). Read More

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http://link.springer.com/10.1007/s00259-018-4094-0
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http://dx.doi.org/10.1007/s00259-018-4094-0DOI Listing
November 2018
5 Reads