6,622 results match your criteria Lymph Node Dissection Pelvic


infection 3 months post-robotic-assisted laparoscopic prostatectomy.

BMJ Case Rep 2019 Apr 12;12(4). Epub 2019 Apr 12.

Urology, NHS Greater Glasgow and Clyde, Glasgow, UK.

infection is a rare bacterial infection with only 46 cases reported from its discovery in 1958. This case highlights an immunocompetent patient who presented with an infected lymphocele and bacteraemia following a robotic-assisted laparoscopic prostatectomy and extended pelvic lymph node dissection 3 months previously. He was treated for a fever of unclear origin initially using amoxicillin, gentamicin and metronidazole. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22818
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http://dx.doi.org/10.1136/bcr-2018-228184DOI Listing
April 2019
1 Read

Totally extraperitoneal approach to laparoscopic lateral lymph node dissection for patients with recurrent lateral pelvic lymph nodes after rectal cancer surgery: a novel technique-M TEP LLND.

Surg Today 2019 Apr 10. Epub 2019 Apr 10.

Department of General and Gastroenterological Surgery, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki, 569-8686, Japan.

Lateral lymph node dissection (LLND) for recurrence of lateral pelvic lymph node metastasis after rectal cancer surgery is technically demanding because of the need for re-do surgery. We herein report a novel technique of laparoscopic LLND via a totally extraperitoneal (TEP) approach. Since October 2018, we have performed LLND based on a TEP approach, called "M TEP LLND", with two cases treated. Read More

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http://dx.doi.org/10.1007/s00595-019-01808-7DOI Listing
April 2019
1 Read

Risk factors of positive surgical margins after robot-assisted radical prostatectomy in high-volume center: results in 732 cases.

J Robot Surg 2019 Apr 5. Epub 2019 Apr 5.

Department of Urology, University of Verona, Verona, Italy.

The aim of the study was to evaluate clinical, pathological and peri-operative factors associated with the risk of positive surgical margins (PSM) after robot-assisted radical prostatectomy (RARP) in a high-volume center. The study is a retrospective analysis of prospectively collected data. We excluded cases who were under androgen deprivation or had prior treatments. Read More

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http://dx.doi.org/10.1007/s11701-019-00954-xDOI Listing

Robotic intracorporeal ileal conduit: Technical aspects.

Arch Esp Urol 2019 04;72(3):299-308

Catherine & Joseph Aresty Department of Urology. USC Institute of Urology and the Keck School of Medicine. University of Southern California. Los Angeles. CA. USA.

Objective: To present a review of the technical aspects of robotic intracorporeal ileal conduit  (IC) reconstruction after robot assisted radical cystectomy (RARC). METHODS: A non-systematic review is performed in order  to summarize technical aspects on robot assisted ileal conduit procedure following radical cystectomy in patients with muscle invasive bladder cancer.  RESULTS: Radical cystectomy with pelvic lymph node dissection and urinary diversion is the gold-standard therapy for localized muscle-invasive bladder cancer. Read More

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April 2019
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Robot-assisted extended pelvic lymph node dissection in prostate cancer. When and how?

Arch Esp Urol 2019 04;72(3):257-265

Divisão de Urologia. Faculdade de Medicina da Universidade de São Paulo. Instituto do Câncer do Estado de São Paulo ICESP. São Paulo. Brazil.

Objective: To review the literature evaluating the role of the extended pelvic lymph node dissectione PLND during robot assisted radical prostatectomy (RARP) in the management of PCa patients, as well as the preoperative clinic pathologic factors that predict lymph node metastases (LNM). The technique and current outcomes of robotic ePLND will be presented.

Methods: Medline®/Pubmed® were searched up to august 2018 to find comparative studies of different anatomic limits of pelvic lymph node dissection (PLND) during RARP, open or pure laparoscopic surgery that reported number of nodes retrieved, oncologic outcomes and complications. Read More

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April 2019
3 Reads

Risk factors, complications and management of lymphocele formation after radical prostatectomy: A mini-review.

Int J Urol 2019 Apr 2. Epub 2019 Apr 2.

Department of Urology, University Hospital Dresden, Dresden, Germany.

Lymphocele formation is the most common adverse event of pelvic lymphadenectomy during radical prostatectomy for prostate cancer. Previous studies failed to favor one surgical technique over the other in terms of minimizing its rate. Data on risk factors for its development are still conflicting and warranting further research. Read More

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http://dx.doi.org/10.1111/iju.13964DOI Listing

Radical Prostatectomy and Pelvic Lymph Node Dissection in Kaiser Permanente Southern California: 15-Year Experience.

Perm J 2019 ;23

Department of Urology, Sunset Medical Center, Los Angeles, CA.

Introduction: Radical prostatectomy (RP) with pelvic lymph node dissection (PLND) is the standard treatment of high-risk prostate cancer. High-risk patients and those with lymph node metastasis (LNM) require further treatment. We review outcomes of RP+PLND in Kaiser Permanente Southern California (KPSC). Read More

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http://dx.doi.org/10.7812/TPP/17-233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380477PMC
January 2019
1 Read

Clinical outcomes and costs of robotic surgery in prostate cancer: a multiinstitutional study in Korea.

Prostate Int 2019 Mar 4;7(1):19-24. Epub 2018 May 4.

Department of Nursing Science, College of Nursing, Gachon University, Incheon, Korea.

Background: This study compared the surgical, functional, and oncologic outcomes of robot-assisted laparoscopic radical prostatectomy (RALP), laparoscopic radical prostatectomy (LRP), and retropubic radical prostatectomy (RRP) in Korean men.

Methods: The study population included 864 patients who underwent radical prostatectomy for prostate cancer in the departments of urology of five tertiary hospitals between 2010 and 2011. RALP, LRP, and RRP perioperative, oncological, and functional outcomes as well as complications were assessed. Read More

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http://dx.doi.org/10.1016/j.prnil.2018.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424675PMC
March 2019
1 Read

The prognostic significance of aortic lymph node metastasis in endometrial cancer: Potential implications for selective aortic lymph node assessment.

Gynecol Oncol 2019 Mar 30. Epub 2019 Mar 30.

Division of Epidemiology, The Ohio State University College of Public Health, Columbus, OH, United States of America.

Objectives: To evaluate the prognostic impact of aortic vs. pelvic lymph node (LN) metastasis among women with endometrial cancer (EC).

Methods: Using data from the SEER 18 Registries we identified 3650 women with LN positive (stage IIIC) EC. Read More

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http://dx.doi.org/10.1016/j.ygyno.2019.03.251DOI Listing
March 2019
1 Read

Posterior muscle-fascial reconstruction and knotless urethro-neo bladder anastomosis during robot-assisted radical cystectomy: Description of the technique and its impact on urinary continence.

Arch Ital Urol Androl 2019 Mar 29;91(1):5-10. Epub 2019 Mar 29.

Department of Urology, Policlinic of Abano Terme (Padova); Department of Urology, S. Orsola-Malpighi Hospital, University of Bologna.

Objective: The aim of our study is to describe the use of posterior muscle-fascial reconstruction during urethro-ileal anastomosis in bladder cancer (BC) patients submitted to robot-assisted radical cystectomy (RC) with orthotopic neobladder (ON) and its role in facilitating day- and night-time continence recovery during a 12-month follow up.

Materials And Methods: We prospectively collected data from 42 consecutive patients who underwent RARC with totally intracorporeal ON and extended pelvic lymph node dissection (PLND) at our Institution from June 2014 to October 2017. Prior to the urethro-neobladder anastomosis we reconstructed the Denonvilliers Fascia (DF) as previously described for radical prostatectomy using a bidirectional barbed suture. Read More

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http://dx.doi.org/10.4081/aiua.2019.1.5DOI Listing
March 2019
2 Reads

Current Management of pT3b Prostate Cancer After Robot-assisted Laparoscopic Prostatectomy.

Eur Urol Oncol 2019 Feb 27;2(1):110-117. Epub 2018 May 27.

Department of Urology, Ghent University Hospital, Ghent, Belgium.

Background: Robot-assisted radical prostatectomy (RALP) in high-risk and locally advanced prostate cancer (PCa) is gaining increasing traction. The optimal use of additional treatments for PCa with seminal vesicle invasion (pT3b) after RALP remains ill explored.

Objective: To evaluate the management of pT3b PCa after RALP in current clinical practice. Read More

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http://dx.doi.org/10.1016/j.euo.2018.05.005DOI Listing
February 2019
2 Reads

Internal hernia beneath the left external iliac artery after robotic-assisted laparoscopic prostatectomy with extended pelvic lymph node dissection: a case report.

Surg Case Rep 2019 Mar 28;5(1):49. Epub 2019 Mar 28.

Department of Surgery, Cosmos Hospital, 1131-1 Tomuro, Usuki, 875-0051, Japan.

Background: Formation of an internal hernia beneath a skeletonized pelvic vessel after pelvic lymph node dissection is extremely rare. We report a case of an internal hernia formation beneath the left external iliac artery after a robotic-assisted laparoscopic prostatectomy with extended pelvic lymph node dissection.

Case Presentation: A 72-year-old man visited our hospital complaining of severe lower abdominal pain. Read More

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http://dx.doi.org/10.1186/s40792-019-0609-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439070PMC
March 2019
1 Read

Lymphangiography and Lymphatic Embolization for the Management of Pelvic Lymphocele After Radical Prostatectomy in Prostatic Cancer.

Cardiovasc Intervent Radiol 2019 Mar 27. Epub 2019 Mar 27.

Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.

Purpose: To retrospectively evaluate the short-term outcomes of lymphangiography and lymphatic embolization in the treatment of pelvic lymphocele after radical prostatectomy in patients with prostate cancer.

Materials And Methods: The data of nine, consecutive patients who underwent lymphangiography and lymphatic embolization for pelvic lymphocele after radical prostatectomy with pelvic lymph node dissection (PLND) between January 2016 and May 2018, were retrospectively reviewed. Lymphangiography was performed through inguinal lymph nodes in order to identify the lymphatic leakage. Read More

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http://dx.doi.org/10.1007/s00270-019-02209-6DOI Listing
March 2019
1 Read

[A Case of Laparoscopic Abdominoperineal Resection of Anorectal Malignant Melanoma].

Gan To Kagaku Ryoho 2019 Mar;46(3):573-575

Dept. of Surgery and Endoscopic Surgery, Onomichi General Hospital.

A 56-year-old woman with complaints of anal bleeding and pain visited our hospital, and an elastic soft mass was detected in the anal canal on digital examination.Colonoscopy showed a black Isp polypoid lesion with a black pit from the anal canal to the lower rectum(P-Rb).She was diagnosed with malignant melanoma based on colonoscopic biopsy. Read More

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March 2019
2 Reads

[Locally Advanced Rectal Cancer Presenting with Perforation That Was Successfully Resected after Preoperative Chemotherapy with mFOLFOX6 plus Panitumumab].

Gan To Kagaku Ryoho 2019 Mar;46(3):475-477

Dept. of Surgery, Kure Kyosai Hospital.

We report a case of locally advanced rectal cancer presenting with perforation that was successfully resected after preoperative chemotherapy. A 66-year-old woman visited our emergency room complaining of lower abdominal pain. Abdominal CT showed a rectal tumor with fluid collection and free air in the pelvis. Read More

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March 2019
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[A Case of Recurrence in the Lateral Pelvic Lymph Node after Local Excision of Lower Rectal pT1a Cancer].

Gan To Kagaku Ryoho 2019 Feb;46(2):363-365

Dept. of Surgery, Yao Municipal Hospital.

The patient was a man in his 70s who visited our hospital to undergo an examination for fecal occult blood, which detected a 20 mm, Ⅱa lesion in the lower rectum on colonoscopy. He was diagnosed with SM-invasive cancer and was planned to undergo trans-anal local excision. After the surgery, he had a good postoperative course without complications. Read More

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February 2019
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The impact of completeness of last transurethral resection of bladder tumors on the outcomes of radical cystectomy.

World J Urol 2019 Mar 25. Epub 2019 Mar 25.

Klinik für Urologie, Luzerner Kantonsspital, Lucerne, Switzerland.

Purpose: To evaluate the role of a complete transurethral resection of bladder tumors (c-TURBT) on oncological outcomes after radical cystectomy (RC) and its relationship with adverse pathological features.

Methods: We retrospectively analyzed data of 727 patients treated with RC and bilateral pelvic lymph node dissection at three tertiary referral centers. Possible c-TURBT was reported by the treating surgeon. Read More

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http://link.springer.com/10.1007/s00345-019-02734-6
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http://dx.doi.org/10.1007/s00345-019-02734-6DOI Listing
March 2019
4 Reads

Pelvic Lymphadenectomy; Step-By-Step Surgical Education Video

J Turk Ger Gynecol Assoc 2019 03 25. Epub 2019 Mar 25.

Department of Gynecologic Oncology, Health Sciences University, Zekai Tahir Burak Woman’s Health Education and Research Hospital, Ankara, Turkey

Pevic lymph node dissection is one of the leading surgical procedures in gynecologic oncology practice. Learning the proper technique with anatomical landmarks will improve the surgical skills and confidence. This video demonstrates a right side systematic pelvic lymphadenectomy in a cadaveric model. Read More

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http://dx.doi.org/10.4274/jtgga.galenos.2019.2018.0167DOI Listing
March 2019
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Lymphatic micrometastases predict biochemical recurrence in patients undergoing radical prostatectomy and pelvic lymph node dissection for prostate cancer.

Aktuelle Urol 2019 Mar 21. Epub 2019 Mar 21.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Klinik für Urologie, Campus Mitte, Berlin.

Background:  Nodal metastasis is a strong prognostic parameter in prostate cancer (PCa). We analysed the detection of micrometastases (miN + ) in initially nodal-negative (pN0) radical prostatectomy specimens from pT2a-c and pT3a PCa patients by immunohistochemistry (IHC).

Material And Methods:  A total of 2352 lymph nodes of 193 PCa patients were centrally re-examined for miN + or miN- status using IHC. Read More

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http://dx.doi.org/10.1055/a-0856-6545DOI Listing
March 2019
1 Read

Laparoscopic resection of a dumbbell-shaped lipoma extending through the obturator foramen: A case report.

Asian J Endosc Surg 2019 Mar 19. Epub 2019 Mar 19.

Division of Lower Gastrointestinal Surgery, Department of Surgery, Hyogo College of Medicine, Nishinomiya, Japan.

Lipomas are often lightweight and small in size with few subjective symptoms. Giant lipomas are uncommon. We herein report a case involving a giant, deep-seated dumbbell-shaped intermuscular lipoma in the right thigh that extended into the pelvic region through the obturator foramen and caused obturator neuropathy. Read More

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http://dx.doi.org/10.1111/ases.12700DOI Listing
March 2019
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Correlation Between Pelvic Peritoneal Disease and Nodal Metastasis in Advanced Ovarian Cancer: Can Intraoperative Findings Define the Need for Systematic Nodal Dissection?

Indian J Surg Oncol 2019 Feb 7;10(Suppl 1):84-90. Epub 2019 Feb 7.

1Department Peritoneal Oncology, Saifee Hospital, Mumbai, India.

To explore the relationship of peritoneal, and rectal involvement with lymph nodal metastases to identify clinical parameters to guide systematic nodal dissection in advanced ovarian cancer (stage 3c). It is a retrospective study of stage III C epithelial ovarian cancers undergoing cytoreductive surgery with systematic nodal dissection, from January 2011 to December 2016. LS3 score is a cumulative score given for the presence of size 3 lesion (peritoneal disease measuring more than 5 cm) in regions 5, 6, and 7. Read More

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http://dx.doi.org/10.1007/s13193-019-00881-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397118PMC
February 2019
1 Read

Predictors of Lymphoceles in Women Who Underwent Laparotomic Retroperitoneal Lymph Node Dissection for Early Gynecologic Cancer: A Retrospective Cohort Study.

Int J Environ Res Public Health 2019 Mar 15;16(6). Epub 2019 Mar 15.

Department of Obstetrics and Gynecology, Far Eastern Memorial Hospital, Banqiao, New Taipei 220, Taiwan.

Lymphoceles could represent a detrimental complication after retroperitoneal lymph node dissection. Our aim was to elucidate predictors of lymphoceles. Between 2011 and 2017, medical records of consecutive women who underwent laparotomic retroperitoneal lymph node dissection for FIGO stage I or II gynecologic cancer were reviewed. Read More

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http://dx.doi.org/10.3390/ijerph16060936DOI Listing
March 2019
1 Read

Step-by-step technique for single-port robot-assisted radical cystectomy and pelvic lymph nodes dissection using the da Vinci SP™ surgical system.

BJU Int 2019 Mar 13. Epub 2019 Mar 13.

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.

Objectives: To describe a step-by-step technique for robot-assisted radical cystectomy (RARC) with pelvic lymph node dissection (PLND) performed using the da Vinci SP™ surgical system (Intuitive Surgical Inc., Sunnyvale, CA, USA).

Patients And Methods: Four consecutive patients diagnosed with urothelial carcinoma of the bladder were counselled for RARC with PLND and ileal conduit urinary diversion performed using the da Vinci SP surgical system. Read More

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http://dx.doi.org/10.1111/bju.14744DOI Listing
March 2019
9 Reads

Management of positive lymph nodes following radical prostatectomy.

Arch Esp Urol 2019 Mar;72(2):182-191

Department of Urology and Robot-assisted and Reconstructive Surgical Urology. University of Cologne. Cologne. Germany.

Oligometastatic prostate cancer (PCA) has increasingly been detected in the era of modern imaging studies such as choline-specific and prostate-specific membrane antigen (PSMA)-positron emission tomography and X-ray computed tomography (PET/CT). Recent evidence suggests that durable control is attainable with local treatment modalities such as salvage metastasectomy or stereotactic radiation therapy targeting oligometastases, either with or without the use of systemic therapy.The purpose of this article is to critically review the current findings on the indication, extent, and oncologic outcome of salvage lymphadenectomy (SLND). Read More

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March 2019
2 Reads

The Outcome of Post-Chemotherapy Retroperitoneal Lymph Node Dissection in Patients with Metastatic Bladder Cancer in the Retroperitoneum.

Bladder Cancer 2019 Jan 31;5(1):13-19. Epub 2019 Jan 31.

Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Purpose: While a definitive cure can be achieved by radical cystectomy and pelvic lymph node dissection in select patients with regional lymphadenopathy, the benefit remains uncertain in patients who present with non-regional metastases. We analyzed the survival outcomes of post-chemotherapy retroperitoneal lymph node dissection.

Materials And Methods: We reviewed our institutional database and identified 13 patients with radiographically evident or biopsy proven retroperitoneal nodal metastases with a significant response to chemotherapy. Read More

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http://dx.doi.org/10.3233/BLC-180186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401561PMC
January 2019
1 Read

Human epidermal growth factor receptor 2 amplification as a biomarker for treatment in patients with lymph node-metastatic penoscrotal extramammary Paget's disease.

Oncol Lett 2019 Mar 14;17(3):2677-2686. Epub 2019 Jan 14.

Department of Urology, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.

The role of human epidermal growth factor receptor 2 (HER2) amplification as a biomarker for treatment in patients with lymph node (LN)-metastatic penoscrotal extramammary Paget's disease (EMPD) was investigated in the present study. A total of 11 male patients with LN-metastatic penoscrotal EMPD were retrospectively reviewed. Positron emission tomography/computed tomography (PET/CT) was conducted prior to surgery. Read More

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http://dx.doi.org/10.3892/ol.2019.9930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365939PMC
March 2019
3 Reads

Evaluation of Cause of Death After Radical Cystectomy for Patients With Bladder Cancer: The Impact of Age at the Time of Surgery.

Clin Genitourin Cancer 2019 Feb 13. Epub 2019 Feb 13.

Unit of Urology/Division of Oncology, IRCCS Ospedale San Raffaele, URI Milan, Milan, Italy.

Introduction: Patients with bladder cancer treated with radical cystectomy (RC) have heterogeneous results in term of cancer-specific (CSM) and other cause mortality (OCM). Our aim is to assess the impact of age on cause of death after RC.

Patients And Methods: We retrospectively analyzed the data of 1222 patients treated with RC and bilateral pelvic lymph node dissection owing to nonmetastatic bladder cancer between 1990 and 2013. Read More

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http://dx.doi.org/10.1016/j.clgc.2019.02.001DOI Listing
February 2019
1 Read

Perioperative venous thromboembolism prophylaxis in prostate cancer surgery.

World J Urol 2019 Mar 6. Epub 2019 Mar 6.

Division of Urology, Department of Surgery, Woodstock General Hospital, Woodstock, ON, Canada.

Purpose: To describe a patient and procedure specific approach to selecting Venous thromboembolism (VTE) prophylaxis for men who undergo radical prostatectomy.

Methods: We performed a literature search and narrative review of VTE after radical prostatectomy. We describe the current paradigm of perioperative thromboprophylaxis and underlying rationale. Read More

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http://dx.doi.org/10.1007/s00345-019-02705-xDOI Listing
March 2019
3 Reads

Robotic Radical Cystectomy with Intracorporeal Studer Pouch Formation for Bladder Cancer: Experience in Ninety-Eight Cases.

J Endourol 2019 Mar 30. Epub 2019 Mar 30.

2 Department of Urology, School of Medicine, Koç University, Istanbul, Turkey.

Aim: To report the outcomes of robot-assisted radical cystectomy (RARC) with bilateral extended pelvic lymph node dissection (BEPLND) and intracorporeal Studer pouch formation for bladder cancer.

Materials And Methods: Overall 98 patients (92 males, 6 females) were included. Patient demographics, operative and postoperative variables, pathological parameters, complications, and functional outcomes were evaluated. Read More

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http://dx.doi.org/10.1089/end.2019.0036DOI Listing
March 2019
4 Reads

[A Case of Advanced Right Renal Pelvic Cancer with Left Supraclavicular Lymph Node Metastasis that Attained Long-Term Survival by Multidisciplinary Treatments].

Hinyokika Kiyo 2019 Jan;65(1):13-17

The Department of Urology, Kyoto University Hospital.

A man in his 70s was referred to our hospital for further examination of a positive occult blood finding. Imaging studies showed that the patient had right renal pelvic cancer with interaortocaval, multiple paracaval and left supraclavicular lymph node metastases (cT3N2Ml). Induction chemotherapy was performed with 5 cycles of MEC (methotrexate/epirubicin/cisplatin) followed by 2 cycles of GT (gemcitabine/paclitaxel). Read More

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http://dx.doi.org/10.14989/ActaUrolJap_65_1_13DOI Listing
January 2019
2 Reads

[Infected Pelvic Lymphocele after Robot-Assisted Radical Prostatectomy].

Hinyokika Kiyo 2019 Jan;65(1):1-6

The Department of Urology, Hiroshima City Asa Hospital.

The aim of this study is to clarify the incidences of infected pelvic lymphocele (IPL) after robot-assisted radical prostatectomy (RARP). From 2016 to 2017, we evaluated 173 consecutive patients who underwent RARP. The transperitoneal approach was used for the RARPs. Read More

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http://dx.doi.org/10.14989/ActaUrolJap_65_1_1DOI Listing
January 2019
2 Reads

Pattern of metastatic deposit in recurrent prostate cancer: a whole-body MRI-based assessment of lesion distribution and effect of primary treatment.

World J Urol 2019 Mar 2. Epub 2019 Mar 2.

Department of Radiology, Centre Du Cancer and Institut de Recherche Expérimentale Et Clinique (IREC, IMAG), Cliniques Universitaires Saint-Luc, Université Catholique de Louvain (UCLouvain), Avenue Hippocrate 10, 1200, Brussels, Belgium.

Purpose: It is generally accepted that when metastases develop in a patient with biochemical recurrence of prostate cancer (PCa), they follow a centrifuge pattern of seeding from the pelvis and that most patients enter the disease as oligometastatic. In this study, we used whole-body magnetic resonance imaging (WB-MRI) to assess the anatomical distribution of oligo- and polymetastatic disease and the impact of the initial treatment on this distribution in patients.

Materials And Methods: WB-MRI examinations of patients with a rising prostate-specific antigen (PSA) after radical treatment by surgery or/and radiotherapy were analyzed for disease recurrence. Read More

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http://dx.doi.org/10.1007/s00345-019-02700-2DOI Listing
March 2019
2 Reads

Modelling Study with an Interactive Model Assessing the Cost-effectiveness of Ga Prostate-specific Membrane Antigen Positron Emission Tomography/Computed Tomography and Nano Magnetic Resonance Imaging for the Detection of Pelvic Lymph Node Metastases in Patients with Primary Prostate Cancer.

Eur Urol Focus 2019 Feb 27. Epub 2019 Feb 27.

Department of Operating Rooms, Radboud University Medical Centre, Nijmegen, The Netherlands; Department of Health Evidence, Radboud University Medical Centre, Nijmegen, The Netherlands.

Background: Outcomes of extended pelvic lymph node dissection (ePLND) show that only 16% of prostate cancer (PCa) patients harbour lymph node (LN) metastases. Ga-68 prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) and nano magnetic resonance imaging (nano-MRI) might be noninvasive alternatives for ePLND; however, it remains uncertain whether they are cost-effective.

Objective: To develop an interactive model to determine the cost-effectiveness of Ga PSMA PET/CT and nano-MRI as compared with ePLND for the detection of pelvic LN metastases in patients with intermediate- to high-risk PCa. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24054569193003
Publisher Site
http://dx.doi.org/10.1016/j.euf.2019.02.013DOI Listing
February 2019
8 Reads

Rise in Node-Positive Prostate Cancer Incidence in Context of Evolving Use and Extent of Pelvic Lymphadenectomy.

Clin Genitourin Cancer 2019 Jan 26. Epub 2019 Jan 26.

Department of Urology, Emory University School of Medicine, Atlanta, GA; Winship Cancer Institute, Emory Healthcare, Atlanta, GA; Atlanta Veterans Affairs Medical Center, Decatur, GA. Electronic address:

Background: The incidence of node-positive prostate cancer has risen and might be partially explained by evolving use of lymphadenectomy at a population level. We assessed trends of node-positive prostate cancer in context of extent of lymphadenectomy among men treated surgically for prostate cancer.

Patients And Methods: This was a retrospective study using data from a population-based cancer registry to identify men older than 50 years of age diagnosed with prostate cancer from 2010 to 2015 without distant metastases. Read More

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http://dx.doi.org/10.1016/j.clgc.2019.01.012DOI Listing
January 2019

Robotic radical prostatectomy in 93 cases: Outcomes of the first ERUS robotic urology curriculum trained surgeon in Turkey.

Turk J Urol 2019 Feb 4. Epub 2019 Feb 4.

Clinic of Urology, Ankara Atatürk Training and Research Hospital, Ankara, Turkey.

Objective: This study presents the surgical, oncological, and functional outcomes of the first 93 robotic radical prostatectomy (RARP) procedures performed in Erzurum, Turkey. These procedures were performed by a single surgeon who had completed the European Association of Urology Robotic Urology Section (ERUS) RARP curriculum in an ERUS-certified training center in Ankara.

Material And Methods: The mean patient age was 63. Read More

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http://turkishjournalofurology.com/eng/makale/3461/155/Full-
Publisher Site
http://dx.doi.org/10.5152/tud.2019.24444DOI Listing
February 2019
2 Reads

A Randomized Trial of Lymphadenectomy in Patients with Advanced Ovarian Neoplasms.

N Engl J Med 2019 02;380(9):822-832

From the Department of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte, Essen (P. Harter, A. du Bois), Department of Gynecology, Charité-Universitätsmedizin Berlin, Berlin (J.S.), the Coordinating Center for Clinical Trials, Philipps University Marburg (A.R., C.S.-B.), and the Department of Gynecology and Obstetrics, University Hospital Giessen and Marburg (U.W.), Marburg, the Department of Gynecology and Obstetrics, Kaiserswerther Diakonie (B.L.), and the Department of Obstetrics and Gynecology, Heinrich-Heine-University Düsseldorf (W.M.), Düsseldorf, the Department of Gynecology and Obstetrics, University Medicine Greifswald, Greifswald (A.M.), the Department of Gynecology, University Medical Center Hamburg-Eppendorf (S.M.), and the Department of Gynecology and Obstetrics, Albertinen Krankenhaus (I.L.), Hamburg, University Women's Hospital, Department of Gynecology and Reproductive Medicine and Center for Gynecologic Oncology, Jena University Hospital, Jena (I.B.R.), the Department of Obstetrics and Gynecology, University Munich rechts der Isar (B.S.), and the Department of Obstetrics and Gynecology, University Hospital, Ludwig-Maximilians-Universität München (A. Burges), Munich, West German Cancer Center, Department of Gynecology and Obstetrics, University of Duisburg-Essen, Duisburg (R.K.), the Department of Gynecology and Obstetrics, University Hospital Kiel, Kiel (F.H.), University Medical Center Freiburg, Freiburg (A.H.), University Medical Center Mainz, Department of Gynecology and Obstetrics, Mainz (A.H.), and the Department of Gynecology and Obstetrics, Hannover Medical School, Hannover (P. Hillemanns) - all in Germany; the Gynecologic Oncology Unit, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Istituto Nazionale Tumori (D.L., F.R.), and the Department of Gynecologic Oncology, European Institute of Oncology, University of Milan (G.A.), Milan, the Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome (G.S.), Gynecologic Oncology, Istituto Nazionale per lo Studio e la Cura dei Tumori di Napoli, IRCCS Fondazione G. Pascale, Naples (S.G.), and the Cancer Reference Center, Centro di Riferimento Oncologico, Aviano (G.G.) - all in Italy; the Department of Gynecological Oncology, University Hospitals Leuven, Leuven Cancer Institute, Leuven, Belgium (I.V.); the Department of Obstetrics and Gynecology, Medical University Innsbruck, Innsbruck, Austria (C.M.); the Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, South Korea (J.-W.K.); and the Gynecologic Oncology Center, Department of Obstetrics and Gynecology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic (D.C.).

Background: Systematic pelvic and paraaortic lymphadenectomy has been widely used in the surgical treatment of patients with advanced ovarian cancer, although supporting evidence from randomized clinical trials has been limited.

Methods: We intraoperatively randomly assigned patients with newly diagnosed advanced ovarian cancer (International Federation of Gynecology and Obstetrics stage IIB through IV) who had undergone macroscopically complete resection and had normal lymph nodes both before and during surgery to either undergo or not undergo lymphadenectomy. All centers had to qualify with regard to surgical skills before participation in the trial. Read More

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http://dx.doi.org/10.1056/NEJMoa1808424DOI Listing
February 2019
5 Reads

Selective tetramodal bladder-preservation therapy, incorporating induction chemoradiotherapy and consolidative partial cystectomy with pelvic lymph node dissection for muscle-invasive bladder cancer: oncological and functional outcomes of 107 patients.

BJU Int 2019 Feb 27. Epub 2019 Feb 27.

Department of Urology, Tokyo Medical and Dental University, Tokyo, Japan.

Objectives: To evaluate the oncological and functional outcomes associated with selective tetramodal bladder-sparing therapy, comprising maximal transurethral resection of bladder tumour (TURBT), induction chemoradiotherapy (CRT), and consolidative partial cystectomy (PC) with pelvic lymph node dissection (PLND).

Materials And Methods: In the present study, 154 patients with non-metastatic muscle-invasive bladder cancer (MIBC), prospectively enrolled in the tetramodal bladder-preservation protocol, were analysed. After TURBT and induction CRT, patients showing complete remission were offered consolidative PC with PLND for the achievement of bladder preservation. Read More

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http://doi.wiley.com/10.1111/bju.14736
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http://dx.doi.org/10.1111/bju.14736DOI Listing
February 2019
6 Reads

Sentinel bruising as a presentation of metastatic melanoma.

BMJ Case Rep 2019 Feb 25;12(2). Epub 2019 Feb 25.

Medical Oncology, Portsmouth Hospitals NHS Trust, Portsmouth, UK.

A 46-year-old man presented with a 4-week history of bruising with subcutaneous nodules and weight loss. He also had a 2-week history of progressive back and hip pain. He had been diagnosed with stage Ib cutaneous melanoma 30 months previously, which had been fully excised. Read More

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http://dx.doi.org/10.1136/bcr-2018-228114DOI Listing
February 2019
3 Reads

[Internal herniation underneath the left external iliac artery after radical prostatectomy with extensive lymph node dissection].

Authors:
Erik Frostberg

Ugeskr Laeger 2019 Feb;181(9)

A 65-year-old male underwent acute surgery because of a partly ischaemic small intestine due to internal herniation underneath the left external iliac artery. The iatrogenic defect in the peritoneum was created 15 months earlier, when the patient had a robot-assisted radical prostat-ectomy with pelvic lymph node dissection performed. The ischaemic small bowel was resected under a laparotomy, and creation of a temporary stoma was necessary. Read More

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February 2019
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Development of symptomatic lymphoceles after radical prostatectomy and pelvic lymph node dissection is independent of surgical approach: a single-center analysis.

Int Urol Nephrol 2019 Apr 22;51(4):633-640. Epub 2019 Feb 22.

Department of Urology and Pediatric Urology, Mainz University Medicine, Langenbeckstr. 1, 55131, Mainz, Germany.

Purpose: Lymphocele (LC) is the most common adverse sequela of pelvic lymphadenectomy (PLND) during radical prostatectomy for prostate cancer. Current evidence on comparison between robotic (RARP) and open retropubic prostatectomy (RRP) in terms of the development of symptomatic LCs (SLCs) is conflicting. Moreover, no single-center assessment has illuminated the impact of the anterior vs. Read More

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http://link.springer.com/10.1007/s11255-019-02103-7
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http://dx.doi.org/10.1007/s11255-019-02103-7DOI Listing
April 2019
5 Reads

Contemporary trends of pelvic lymph node dissection at radical cystectomy for urothelial carcinoma of urinary bladder and associated cancer specific mortality and complications: comparison between octogenarian versus younger patients.

Cancer Epidemiol 2019 Apr 13;59:135-142. Epub 2019 Feb 13.

Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Québec, Canada; Division of Urology, University of Montreal Hospital Center (CHUM), Montreal, Quebec, Canada.

Background: We analysed contemporary pelvic lymph node dissection (PLND) trend during radical cystectomy (RC) for urothelial carcinoma of urinary bladder (UCUB), as well as PLND association with cancer specific mortality (CSM) and complications after stratification according to octogenarian vs. younger age.

Materials And Methods: Within the SEER and NIS databases, respectively 10,427 (T2 and T3 stages) and 19,203 (all T-stages) RC patients (2004-2015) for UCUB were identified. Read More

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http://dx.doi.org/10.1016/j.canep.2019.02.002DOI Listing
April 2019
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Extended pelvic lymphadenectomy for prostate cancer: should the cloquet's nodes dissection be considered only an option?

Minerva Urol Nefrol 2019 Feb 14. Epub 2019 Feb 14.

Department of Urology, University of Verona, Verona, Italy.

Background: To assess the anatomical prevalence and secondary involvement of Cloquet's nodes in patients undergoing robotic radical prostatectomy (RRP) and extended pelvic lymph node dissection (ePLND) for prostate cancer (PCa).

Methods: RRP and ePLND were performed by two expert surgeons (WA and VDM). Data were prospectively collected and retrospectively analysed. Read More

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http://dx.doi.org/10.23736/S0393-2249.19.03342-3DOI Listing
February 2019

8-armed octopus: Evaluation of clinicopathologic prognostic factors of urothelial carcinoma of the upper urinary system

Turk J Med Sci 2019 Feb 11;49(1):153-161. Epub 2019 Feb 11.

Background/aim: This study was designed to determine the characteristic features of upper urinary system urothelial carcinomas (UUSUCs) and to evaluate the clinicopathological parameters associated with prognosis.

Materials And Methods: A total of 74 cases of UUSUC were included, from three different centers. Demographic data and histopathological features such as tumor localization, concomitant tumor in the urinary system, distant metastasis with overall survival and disease-free survival obtained from the hospital records were evaluated retrospectively. Read More

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http://dx.doi.org/10.3906/sag-1805-51DOI Listing
February 2019
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Multiple cutaneous metastasis of synchronous urothelial carcinoma of the bladder and the renal pelvis: a case report.

J Med Case Rep 2019 Feb 14;13(1):34. Epub 2019 Feb 14.

Surgical Oncology Department, Institute Salah Azaiez de Cancer, Tunis, Tunisia.

Introduction: Cutaneous metastatic disease arising from urinary tract carcinoma is rare and associated with a poor prognosis. We report a case of metastatic disease occurring in a patient treated for synchronous urothelial tumor of the bladder and left renal pelvis.

Case Presentation: A 61-year-old Caucasian man was treated for a synchronous urothelial tumor of the bladder and left renal pelvis. Read More

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http://dx.doi.org/10.1186/s13256-019-1997-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375173PMC
February 2019
1 Read

Difficulty of predicting lymph node metastasis on CT in patients with rectal neuroendocrine tumors.

PLoS One 2019 11;14(2):e0211675. Epub 2019 Feb 11.

Department of Gastroenterological Surgery, Gastroenterological Center, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Koto-ku, Tokyo, Japan.

Background: Surgical indications for rectal neuroendocrine tumors with potential lymph node metastasis remain controversial. Although accurate preoperative diagnosis of nodal status may be helpful for treatment strategy, scant data about clinical values of lymph node size have been reported. The aim of this retrospective study was to investigate the relationship between lymph node size and lymph node metastasis. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0211675PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370204PMC
February 2019
2 Reads

SLN mapping in early-stage cervical cancer as a minimal-invasive triaging tool for multimodal treatment.

Eur J Surg Oncol 2019 04 30;45(4):679-683. Epub 2019 Jan 30.

Department of Obstetrics and Gynecology, University Hospital of Bern and University of Berne, Berne, Switzerland.

Background: To evaluate sensitivity, false negative rate and negative predictive value of the combination of sentinel lymph node (SLN) mapping and frozen section (FS) in triaging cervical cancer patients to a definitive chemo-radiotherapy.

Methods: A retrospective analysis of patients with histologically proven cervical cancer undergoing laparoscopic SLN mapping and frozen section of the SLNs followed by a completion radical hysterectomy, pelvic and/or paraarotic lymphadenectomy. Sensitivity, false negative rate and negative predictive value of the SLN mapping, of the frozen section and of the combination of the two in identifying micro- and macrometastases were calculated. Read More

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http://dx.doi.org/10.1016/j.ejso.2019.01.184DOI Listing
April 2019
3 Reads

Accurate Quantification of Residual Cancer Cells in Pelvic Washing Reveals Association with Cancer Recurrence Following Robot-Assisted Radical Cystectomy.

J Urol 2019 Feb 5:101097JU0000000000000142. Epub 2019 Feb 5.

Department of Urology, Roswell Park Comprehensive Cancer Center , Buffalo , New York.

Purpose: Bladder cancer recurrence following cystectomy remains a significant cause of bladder cancer specific mortality. Residual cancer cells contribute to cancer recurrence due to tumor spillage or undetectable preexisting micrometastatic tumor clones. We detected and quantified residual cancer cells in pelvic washing using ultradeep targeted sequencing. Read More

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http://dx.doi.org/10.1097/JU.0000000000000142DOI Listing
February 2019
10 Reads
4.471 Impact Factor

Important surgical concepts and techniques in inguinal lymph node dissection.

Curr Opin Urol 2019 May;29(3):286-292

Department of Genitourinary Oncology, Moffitt Cancer Center, Tampa, Florida, USA.

Purpose Of Review: Penile cancer is a rare disease with significant physical and psychosocial morbidity. It has a propensity to spread to the inguinal lymph nodes where it can progress to the pelvis and beyond. Here, we present a contemporary review on the surgical management of the lymph nodes. Read More

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http://dx.doi.org/10.1097/MOU.0000000000000591DOI Listing
May 2019
7 Reads
2.333 Impact Factor

Optimal treatment strategy for rectal cancer based on the risk factors for recurrence patterns.

Int J Clin Oncol 2019 Feb 5. Epub 2019 Feb 5.

Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

Background: For rectal cancer, multimodality therapeutic approach is necessary to prevent local recurrence and distant metastasis. However, the efficacy of additional treatments, such as neoadjuvant chemoradiotherapy (nCRT), neoadjuvant chemotherapy (NAC), and lateral pelvic lymph node dissection (LPLND), has not been scrutinized.

Methods: Recurrence patterns were categorized into local recurrence and distant metastasis. Read More

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http://dx.doi.org/10.1007/s10147-019-01400-6DOI Listing
February 2019
4 Reads

Long term complications following pelvic and para-aortic lymphadenectomy for endometrial cancer, incidence and potential risk factors: a single institution experience.

Int J Gynecol Cancer 2019 Feb 18;29(2):312-319. Epub 2019 Jan 18.

Department of Gynecology and Obstetrics, University of Parma, Parma, Italy.

Objective: To determine the incidence of long term lymphadenectomy complications in primary surgery for endometrial cancer and to elucidate risk factors for these complications.

Methods: A retrospective chart review was carried out for all patients with endometrial cancer managed at Parma University Hospital Unit of Gynecology and Obstetrics between 2010 and 2016. Inclusion criteria were surgical procedure including hysterectomy and lymphadenectomy (pelvic or pelvic and aortic). Read More

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http://dx.doi.org/10.1136/ijgc-2018-000084DOI Listing
February 2019
7 Reads