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    Disseminated extrafacial rosacea with papulonecrotic lesions.
    J Dermatol Case Rep 2016 Dec 31;10(4):68-72. Epub 2016 Dec 31.
    Department of Dermatology, Jichi Medical University Saitama Medical Center, Japan.
    Background: Rosacea is a common skin disease and predominantly affects on the face of middle-aged women. It exceptionally occurs on the extrafacial areas such as ear, neck, axilla, and upper extremities, and has been reported as disseminated rosacea.

    Main Observation: A 40-year-old Japanese female presented with one-month history of erythematous skin eruption with burning sensation on the face, neck, and upper limbs. Read More

    Alcohol intake and risk of rosacea in US women.
    J Am Acad Dermatol 2017 Apr 1. Epub 2017 Apr 1.
    Department of Dermatology, Warren Alpert Medical School, Brown University, Providence, Rhode Island; Department of Epidemiology, School of Public Health, Brown University, Providence, Rhode Island. Electronic address:
    Background: The epidemiologic association between alcohol and rosacea is unclear and inconsistent based on the previous cross-sectional or case-control studies.

    Objective: We conducted a cohort study to determine the association between alcohol intake and the risk of rosacea in women.

    Methods: A total of 82,737 women were included from the Nurses' Health Study II (1991-2005). Read More

    Minocycline-Induced Hyperpigmentation in a Patient Treated with Erlotinib for Non-Small Cell Lung Adenocarcinoma.
    Case Rep Oncol 2017 Jan-Apr;10(1):156-160. Epub 2017 Feb 15.
    Walter Reed National Military Medical Center, Bethesda, MD, USA.
    Introduction: While epidermal growth factor receptor (EGFR) inhibitors have improved progression-free survival in patients with non-small cell lung cancer (NSCLC), one of the most common adverse effects is papulopustular skin eruption, which is frequently severe enough to be treated with oral minocycline or doxycycline.

    Case: We present a case of an 87-year-old man who developed a severe papulopustular skin eruption secondary to erlotinib therapy for NSCLC. Control of the eruption with 100 mg of minocycline twice daily for 8 months eventually led to blue-gray skin hyperpigmentation. Read More

    [Granulomatous periocular eruption].
    Ann Dermatol Venereol 2017 Apr 11. Epub 2017 Apr 11.
    Clinique universitaire de dermatologie, allergologie et photobiologie, CHU de Grenoble, boulevard de la Chantourne, 38700 La Tronche, France.
    Background: Herein, we report a case of atypical periorificial dermatitis in a patient that had been receiving treatment for some time for atopic dermatitis. The specific feature of this rash was its periocular predominance with no perioral involvement, its clinical aspect and its histological picture evocative of sarcoidosis.

    Patients And Methods: A 33-year-old man was being treated for a atopic dermatitis limited to the face and poorly responsive to dermal corticosteroids. Read More

    Dermatological comorbidity in psoriasis: results from a large-scale cohort of employees.
    Arch Dermatol Res 2017 Apr 12. Epub 2017 Apr 12.
    German Center for Health Services Research in Dermatology (CVderm), Institute for Health Services Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
    The field of dermatological comorbidity in psoriasis is only passively explored with contradictory results. Objective of this study was to further investigate the complex field of psoriasis and associated skin diseases by identifying skin comorbidity patterns in an extensive cohort of employees in Germany. Retrospective analysis of data deriving from occupational skin cancer screenings was conducted. Read More

    Rosacea Subtypes Visually and Optically Distinct When Viewed with Parallel-Polarized Imaging Technique.
    Ann Dermatol 2017 Apr 24;29(2):167-172. Epub 2017 Mar 24.
    Department of Dermatology, Korea University College of Medicine, Seoul, Korea.
    Background: Parallel-polarized light (PPL) photography evaluates skin characteristics by analyzing light reflections from the skin surface.

    Objective: The aim of this study was to determine the significance of quantitative analysis of PPL images in rosacea patients, and to provide a new objective evaluation method for use in clinical research and practice.

    Methods: A total of 49 rosacea patients were enrolled. Read More

    Demodex Mite Density Determinations by Standardized Skin Surface Biopsy and Direct Microscopic Examination and Their Relations with Clinical Types and Distribution Patterns.
    Ann Dermatol 2017 Apr 24;29(2):137-142. Epub 2017 Mar 24.
    Department of Dermatology, Gachon University School of Medicine, Incheon, Korea.
    Background: Demodicosis is a parasitic skin disease caused by Demodex mites, and the determination of mite density per square centimeter is important to diagnose demodicosis. Standardized skin surface biopsy (SSSB) and direct microscopic examination (DME) are commonly used to determine Demodex mites density (Dd). However, no study has previously compared these two methods with respect to clinical types and distribution patterns of demodicosis. Read More

    New Uses of AbobotulinumtoxinA in Aesthetics.
    Aesthet Surg J 2017 May;37(suppl_1):S45-S58
    Dr Schlessinger is a dermatologist and cosmetic surgeon in private practice in Omaha, NE. Dr Gilbert is a dermatologist in private practice in Brooklyn, NY. Dr Cohen is a dermatologist in private practice in Greenwood Village, CO. Dr Kaufman is dermatologist in private practice in Miami, FL.
    BotulinumtoxinA (BoNT-A) is now widely established for the main approved indication of reducing glabellar lines, and is also widely used off-label to improve the appearance of wrinkles and lines in other parts of the face. The number of aesthetic procedures continues to increase as the patient population becomes more diverse, in particular with increasing numbers of people of color and men. Further developments in treatment may continue to expand the audience for BoNT-A by making procedures more comfortable and by delivering a more natural, less static appearance. Read More

    Microscale coiling in bis-imidazolium supramolecular hydrogel fibres induced by the release of a cationic serine protease inhibitor.
    Chem Commun (Camb) 2017 Apr;53(32):4509-4512
    Departament de Farmacologia, Toxicologia i Química Terapèutica, Universitat de Barcelona, Av. Joan XXIII, 27-31, 08028 Barcelona, Spain.
    Gels formed by a gemini dicationic amphiphile incorporate a serine protease inhibitor, which could be used in a new approach to the treatment of Rosacea, within the fibres as well as in the space between them, affecting a number of gel properties but most importantly inducing remarkable fibre coiling at the microscopic level as a result of drug release from the gel. Drug release and skin permeation experiments show its potential for topical administration. Read More

    Azelaic Acid Topical Formulations: Differentiation of 15% Gel and 15% Foam.
    J Clin Aesthet Dermatol 2017 Mar 1;10(3):37-40. Epub 2017 Mar 1.
    Adjunct Clinical Professor (Dermatology), Touro University Nevada, Henderson, Nevada; Research Director/Principal Investigator, JDR Dermatology Research, LLC, Las Vegas, Nevada; Dermatology and Cutaneous Surgery, Thomas Dermatology, Las Vegas, Nevada.
    In this article, the author reviews topical formulations of azelaic acid used to treat papulopustular rosacea. Emphasis is placed on differences in vehicle technology and potential clinical impact of the possibility for neurosensory cutaneous tolerability reactions. Read More

    Dermasence refining gel modulates pathogenetic factors of rosacea in vitro.
    J Cosmet Dermatol 2017 Mar 27. Epub 2017 Mar 27.
    P&M Cosmetics GmbH & Co. KG, Münster, Germany.
    Background: Over the counter cosmetics sold for local treatment of slight to moderate rosacea often state the claim of actively modulating rosacea pathogenesis. Factors involved in the pathogenesis of this common yet complex skin disorder include kallikrein-related peptidase 5 (KLK5), LL-37, as well as protease-activated receptor 2 (PAR2) and vascular endothelial growth factor (VEGF).

    Objective: The objective was to prove the modulating effect of the cosmetic skin care agent Dermasence Refining Gel (DRG) on factors involved in rosacea pathogenesis. Read More

    Role of high resolution optical coherence tomography in diagnosing ocular surface squamous neoplasia with coexisting ocular surface diseases.
    Ocul Surf 2017 Mar 24. Epub 2017 Mar 24.
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA. Electronic address:
    Purpose: Coexistence of an ocular surface disease can mask the typical features of ocular surface squamous neoplasia (OSSN). The purpose of this study was to evaluate high resolution optical coherence tomography (HR-OCT) as an adjunct in the detection and differentiation of OSSN within coexisting ocular surface pathologies.

    Methods: Retrospective study of 16 patients with ocular surface disease and lesions suspicious for OSSN that were evaluated with HR-OCT. Read More

    Giant Rhinophyma: A Rare Case of Total Nasal Obstruction and Restitutio Ad Integrum.
    Aesthetic Plast Surg 2017 Mar 24. Epub 2017 Mar 24.
    Department of Plastic and Aesthetic Surgery, Florence-Nightingale Hospital, Kaiserswerther Diakonie, Kreuzbergstrasse 79, 40489, Duesseldorf, Germany.
    Rhinophyma is considered the end stage in the development of rosacea, accompanied by hypertrophy of the sebaceous glands, which causes an enlargement of the nose. It is an uncommon condition that often results in both functional and cosmetic impairment. A large variety of surgical and nonsurgical treatments have been published to treat it. Read More

    TRPV4 Moves toward Center-Fold in Rosacea Pathogenesis.
    J Invest Dermatol 2017 Apr;137(4):801-804
    Department of Neurology, Duke University, School of Medicine, Durham, North Carolina, USA; Department of Anesthesiology, Duke University, School of Medicine, Durham, North Carolina, USA; Department of Neurobiology, Duke University, School of Medicine, Durham, North Carolina, USA. Electronic address:
    Mascarenhas et al. report that TRPV4 expression is upregulated in mast cells in response to the proteolytic cathelicidin fragment LL37 in a murine rosacea model and that TRPV4 loss of function attenuates mast cell degranulation. These findings render TRPV4 a translational-medical target in rosacea. Read More

    Skin disorders in Parkinson's disease: potential biomarkers and risk factors.
    Clin Cosmet Investig Dermatol 2017 9;10:87-92. Epub 2017 Mar 9.
    Department of Dermatology and Allergy, Herlev and Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.
    Parkinson's disease (PD) is one of the most common neurodegenerative disorders, characterized by a symptom triad comprising resting tremor, rigidity, and akinesia. In addition, non-motor symptoms of PD are well recognized and often precede the overt motor manifestations. Cutaneous manifestations as markers of PD have long been discussed, and cumulative evidence shows an increased prevalence of certain dermatological disorders in PD. Read More

    Cost of diagnosing psoriasis and rosacea for dermatologists versus primary care physicians.
    Cutis 2017 Feb;99(2):134-136
    Center for Dermatology Research, Departments of Dermatology, Pathology, and Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
    Growing incentives to control health care costs may cause accountable care organizations (ACOs) to reconsider how skin disease is best managed. Limited data have suggested that disease management by a primary care physician (PCP) may be less costly than seeing a specialist, though it is not clear if the same is true for the management of skin disease. This study assessed the cost of seeing a dermatologist versus a PCP for diagnosis of psoriasis and rosacea. Read More

    Morbihan syndrome: a case report and literature review.
    An Bras Dermatol 2016 Sep-Oct;91(5 suppl 1):157-159
    Universidade de Santo Amaro (Unisa) - São Paulo (SP), Brazil.
    Morbihan syndrome is a rare entity that more commonly affects women in the third or fourth decade of life. It is considered a special form of rosacea and its pathogenesis is not fully known. It is clinically characterized by the slow appearance of erythema and solid edemas on the upper portion of the face, with accentuation in the periorbital region, forehead, glabella, nose, and cheeks. Read More

    Rosacea fulminans: unusual clinical presentation of rosacea.
    An Bras Dermatol 2016 Sep-Oct;91(5 suppl 1):151-153
    Fundação Alfredo da Matta (Fuam) - Manaus (AM), Brazil.
    Rosacea fulminans or pyoderma faciale is a rare cutaneous disorder that usually affects women usually between the ages of 15-46. The disease is characterized by sudden onset of papules, pustules, cysts, and painful coalescing nodules with red-cyanotic centrofacial erythema. Although its etiology remains unknown, hormonal, immunological, and vascular factors have been reported. Read More

    Selection of experimental strawberry (Fragaria x ananassa) hybrids based on selection indices.
    Genet Mol Res 2017 Mar 8;16(1). Epub 2017 Mar 8.
    Departamento de Agronomia, Universidade Estadual do Centro-Oeste, Guarapuava, PR, Brasil.
    The strawberry (Fragaria x ananassa Dutch.), is the only vegetable belonging to the rosacea family. All strawberry species have now emerged from wild species and belong to the genus Fragaria, being that this genus presents more than 45 described species, and only 11 are considered natural species. Read More

    Cosmeceuticals for rosacea.
    Clin Dermatol 2017 Mar - Apr;35(2):213-217. Epub 2016 Oct 27.
    Consulting Professor, Department of Dermatology, Duke University School of Medicine, Durham, North Carolina. Electronic address:
    Patients with rosacea present a challenge to the dermatologist, as they typically possess sensitive skin, need facial Demodex and bacterial colonization control, exhibit vasomotor instability, require camouflaging of telangiectatic mats, and desire prescription treatment. Currently available pharmaceuticals are aimed at inflammation reduction, primarily with the use of topical and oral antibiotics. Recently, vasoconstrictor formulations have emerged, but these drugs have only a temporary effect and improve appearance without addressing the underlying cause, which remains largely unknown. Read More

    Pharmacologic treatments for rosacea.
    Clin Dermatol 2017 Mar - Apr;35(2):207-212. Epub 2016 Oct 27.
    Department of Dermatology, Harrogate and District NHS Foundation Trust, Harrogate, United Kingdom. Electronic address:
    Rosacea represents a common and chronic inflammatory skin disorder. Clinical features include transient and permanent erythema, inflammatory papules and pustules, phymatous changes, and ocular signs and symptoms. Rosacea is generally classified into four subtypes and one variant. Read More

    The "red face": Not always rosacea.
    Clin Dermatol 2017 Mar - Apr;35(2):201-206. Epub 2016 Oct 27.
    Department of Dermatology, Andreas Syggros Hospital, University of Athens, 5, Dragoumi str, Athens, 16121, Greece. Electronic address:
    Facial erythema (the "red face") is a straightforward clinical finding, and it is evident even to the untrained eye; however, a red face does not represent a single cutaneous entity. It may be due to a plethora of distinct underlying conditions of varying severity, including rosacea, demodicosis, dermatomyositis, lupus erythematosus, allergic contact dermatitis, drug-induced erythema, and emotional blushing. In clinical practice, dermatologists do not encounter only one type of facial erythema but rather a number of different shades of red. Read More

    Demodex and rosacea revisited.
    Clin Dermatol 2017 Mar - Apr;35(2):195-200. Epub 2016 Oct 27.
    The Charles Institute of Dermatology, University College Dublin, Dublin, Ireland. Electronic address:
    Demodex mites are part of the vast microbiome living on and within human skin. The interaction of the various microorganisms with the skin plays a key role in the maintenance of homeostasis. The precise role and function of Demodex mites within normal and diseased human skin remains elusive. Read More

    [RISK-FSCTORS OF CARDIOVASCULAR DISEASE IN PATIENTS WITH ROSACEA].
    Georgian Med News 2017 Jan(262):49-52
    Tbilisi State Medical University,Department of Dermatology and Venerology, Georgia.
    The purpose of the research was to study the lipid profile, some indices of hemostasis and cytokine status of rosacea patients with severe climacteric syndrome. Serum lipid profile was studied by means of the following parameters: total cholesterol, high density lipoproteins (HDL), low density lipoproteins (LDL), triglycerides (the study of lipid profile was performed by the device "INTEGRAM +400" (Company "ROSH»). Haemostatic system was evaluated in terms of prothrombin, thrombin time. Read More

    Topical Treatment of Rosacea with Ivermectin Inhibits Gene Expression of Cathelicidin Innate Immune Mediators, LL-37 and KLK5, in Reconstructed and Ex Vivo Skin Models.
    Dermatol Ther (Heidelb) 2017 Feb 27. Epub 2017 Feb 27.
    Nestlé Skin Health R&D, Sophia Antipolis, France.
    Introduction: Numerous intrinsic and extrinsic factors have been associated with the pathophysiology of rosacea, including dysregulation of innate immunity. A high level of cathelicidin antimicrobial peptides (e.g. Read More

    Usefulness of dermoscopy in the diagnosis and monitoring treatment of demodicidosis.
    Dermatol Pract Concept 2017 Jan 31;7(1):35-38. Epub 2017 Jan 31.
    Dermatology Department, Instituto de Investigaciones Médicas "A. Lanari", University of Buenos Aires, Argentina.
    Demodicidosis is a common infestation and should be considered in the differential diagnosis of recurrent or recalcitrant perioral dermatitis or rosacea-like eruptions of the face. We report on a 34-year-old male, who presented with facial erythema and desquamation accompanied by a pruritic sensation. Dermoscopic examination revealed Demodex tails and Demodex follicular openings, both specific features of this entity. Read More

    Underrecognized clinical features of folliculotropic mycosis fungoides: a large clinical series.
    J Dtsch Dermatol Ges 2017 Mar 27;15(3):289-299. Epub 2017 Feb 27.
    Department of Pathology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey.
    Background And Objective: A rare variant of mycosis fungoides (MF), folliculotropic MF (FMF) is characterized by a broad clinical spectrum that primarily includes follicle-based lesions but also many atypical clinical manifestations. The objective of the present study was to conduct a clinical analysis of patients with FMF, with a particular focus on highlighting underrecognized dermatological features.

    Patients And Methods: Overall, 27 FMF patients enrolled in our department';s MF registry, which includes 572 patients, were retrospectively reevaluated with regard to demographics, clinical features, treatment modalities, follow-up, and outcomes. Read More

    Epidemiology of rosacea in Colombia.
    Int J Dermatol 2017 May 27;56(5):510-513. Epub 2017 Feb 27.
    Universidad Autónoma de Bucaramanga, Bucaramanga, Colombia.
    Background: Prevalence of rosacea has been estimated around the world in the range of 0-22%. In Colombia, the prevalence of rosacea remains unknown. The aim of this study was to determine the prevalence of rosacea and the frequencies of its subtypes in Colombia. Read More

    Rosacea Fulminans Precipitated by Acute Stress: A Case Report Describing an Integrative Approach for a Patient Reluctant to Use Isotretinoin.
    Integr Med (Encinitas) 2016 Dec;15(6):32-35
    , is a medical student at Indiana University; , is assistant professor of clinical dermatology at Indiana University; is a resident at Geisinger Health.
    Context: Rosacea fulminans is a rare skin disorder with a multifactorial etiology. Stress is one of the common precipitating factors of this condition but is not often targeted in treatment. Isotretinoin is considered part of the first-line therapy for this condition but, in cases where its use is restricted, other therapeutic interventions as part of an integrative approach may be effective. Read More

    Friends or Foes? Host defense (antimicrobial) peptides and proteins in human skin diseases.
    Exp Dermatol 2017 Feb 13. Epub 2017 Feb 13.
    Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan.
    Host defense peptides/proteins (HDPs), also known as antimicrobial peptides/proteins (AMPs), are key molecules in the cutaneous innate immune system. AMPs/HDPs historically exhibit broad-spectrum killing activity against bacteria, enveloped viruses, fungi and several parasites. Recently, AMPs/HDPs were shown to have important biological functions, including inducing cell proliferation, migration and differentiation; regulating inflammatory responses; controlling the production of various cytokines/chemokines; promoting wound healing; and improving skin barrier function. Read More

    Ten-year incidence and prevalence of clinically diagnosed blepharitis in South Korea: a nationwide population-based cohort study.
    Clin Exp Ophthalmol 2017 Feb 9. Epub 2017 Feb 9.
    Department of Ophthalmology, Severance Hospital, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea.
    Importance: Blepharitis is one of the most common conditions. However, no study has yet evaluated the epidemiology by evaluating a large population-based sample.

    Background: To evaluate the incidence and prevalence of clinically diagnosed blepharitis in South Korea. Read More

    Development and clinical validation of a novel photography-based skin erythema evaluation system: a comparison with the calculated consensus of dermatologists.
    Int J Cosmet Sci 2017 Feb 8. Epub 2017 Feb 8.
    Department of Biomedical Engineering, Seoul National University College of Medicine, Seoul, 110-799, Korea.
    Objective: Erythema is the most common presenting sign in patients with skin diseases, and various methods to treat erythema symptoms have become common. To evaluate changes in erythema, a reliable device that can support objective diagnosis is required. We developed a novel photography-based system for erythema diagnosis that provides a high-resolution three-view photograph taken in a consistent photography environment with a curved surface light source and can be integrated with optimized image processing algorithms. Read More

    Activation of p38 and Erk Mitogen-Activated Protein Kinases Signaling in Ocular Rosacea.
    Invest Ophthalmol Vis Sci 2017 Feb;58(2):843-848
    Department of Ophthalmology, Albany Medical College, Albany, New York, United States 5Department of Molecular and Cellular Physiology, Albany Medical College, Albany, New York, United States.
    Purpose: Rosacea-related cutaneous inflammation is a common cause of ocular surface disease. Currently, there are no specific pharmacologic therapies to treat ocular rosacea. Here, we aimed at determining the differences in intracellular signaling activity in eyelid skin from patients with and without ocular rosacea. Read More

    A Report of Two Cases of Solid Facial Edema in Acne.
    Dermatol Ther (Heidelb) 2017 Mar 6;7(1):167-174. Epub 2017 Feb 6.
    Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.
    Introduction: Solid facial edema (SFE) is a rare complication of acne vulgaris. To examine the clinical features of acne patients with solid facial edema, and to give an overview on the outcome of previous topical and systemic treatments in the cases so far published.

    Methods: We report two cases from Switzerland, both young men with initially papulopustular acne resistant to topical retinoids. Read More

    Erythroid Differentiation Regulator 1 as a Novel Biomarker for Hair Loss Disorders.
    Int J Mol Sci 2017 Feb 3;18(2). Epub 2017 Feb 3.
    Department of Dermatology, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 07345, Korea.
    Erythroid differentiation regulator 1 (Erdr1) is known to be involved in the inflammatory process via regulating the immune system in many cutaneous disorders, such as psoriasis and rosacea. However, the role of Erdr1 in various hair loss disorders remains unclear. The aim of this study was to investigate the putative role of Erdr1 in alopecias. Read More

    De novo characterization of microRNAs in oriental fruit moth Grapholita molesta and selection of reference genes for normalization of microRNA expression.
    PLoS One 2017 3;12(2):e0171120. Epub 2017 Feb 3.
    Department of Entomology, China Agricultural University, Beijing, China.
    MicroRNAs (miRNAs) are a group of endogenous non-coding small RNAs that have critical regulatory functions in almost all known biological processes at the post-transcriptional level in a variety of organisms. The oriental fruit moth Grapholita molesta is one of the most serious pests in orchards worldwide and threatens the production of Rosacea fruits. In this study, a de novo small RNA library constructed from mixed stages of G. Read More

    Four cases of Morbihan disease successfully treated with doxycycline.
    J Dermatol 2017 Feb 2. Epub 2017 Feb 2.
    Department of Dermatology, Kitakami Saiseikai Hospital, Kitakami, Japan.
    Morbihan disease (MD) is rosacea-like disease characterized by persistent lymphedema on the upper half of the face. Currently, there is no established standard treatment for MD. Recently, MD has been reported to be associated with the infiltration of mast cells. Read More

    9th Skin Academy Symposium: Building Bridges in Dermatology Chair's Introduction.
    Dermatol Ther (Heidelb) 2017 Jan 1;7(Suppl 1):1-3. Epub 2017 Feb 1.
    Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
    An introduction to the proceedings sharing an overview of presentations given as part of the 9th Skin Academy Symposium, held in Barcelona, Spain, April 9-10, 2016. The Skin Academy is an international and interdisciplinary dermatology initiative created to contribute to the growth in scientific knowledge of those dealing with skin diseases. This year's meeting aimed to 'build bridges' between the latest research and everyday clinical practice, providing dermatologists with important updates on some of the most common skin diseases, as well as current 'hot' topics. Read More

    Acne and Rosacea.
    Dermatol Ther (Heidelb) 2017 Jan 1;7(Suppl 1):43-52. Epub 2017 Feb 1.
    University of Western Ontario, Windsor, ON, Canada.
    Acne, one of the most common skin diseases, affects approximately 85% of the adolescent population, and occurs most prominently at skin sites with a high density of sebaceous glands such as the face, back, and chest. Although often considered a disease of teenagers, acne is occurring at an increasingly early age. Rosacea is a chronic facial inflammatory dermatosis characterized by flushing (or transient facial erythema), persistent central facial erythema, inflammatory papules/pustules, and telangiectasia. Read More

    A case report of combination treatment with potassium-titanyl phosphate laser and brimonidine topical gel in erythematotelangiectatic rosacea.
    J Cosmet Laser Ther 2017 Jan 31:1-3. Epub 2017 Jan 31.
    a Department of Dermatology , Venerology and Allergology, Charité Universitätsmedizin Berlin , Berlin , Germany.
    Laser therapies have been shown to provide symptom improvement in patients with erythema and telangiectasia of rosacea; however, they are associated with side effects such as erythema. Combinatorial treatment with pharmacological agents and laser have demonstrated better efficacy, fewer side effects and continued long-term remission compared with monotherapies. A case of moderate facial erythema that responded well to combination treatment with brimonidine 3 mg/g gel and a treatment course of potassium-titanyl phosphate (KTP) laser therapy is presented, showing a reduction from baseline, maintained after final laser session, by applying brimonidine 3 mg/g gel daily. Read More

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