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Medicine (Baltimore) 2021 Jun;100(22):e26191

Laboratory of Statistics, Graduate School of Medicine, Osaka City University, Osaka, Japan.

Abstract: Case-control studies by examining the lumbar spine computed tomography (CT) findings focusing on the spinous processes."Passing spine" was defined as a lumbar degenerative change observed on CT images. In contrast, kissing spine, which is also an image finding, has been acknowledged as an established clinical condition. Read More

BMJ Case Rep 2021 May 31;14(5). Epub 2021 May 31.

Acute Medical Unit, Southend Hospital, Westcliff-on-Sea, Essex, UK.

A 65-year-old patient with background of alcohol excess and previous gunshot wounds was admitted with significant weight loss, leg cramps, dizziness and lethargy for the last 3 months. He was diagnosed with type 2 diabetes mellitus in July 2020 and was started on Metformin and Gliclazide by his in July; he was later commenced on alogliptin and empaglaflozin by diabetes specialist nurse in early August. He also had generalised muscle wasting, dorsal guttering in both hands and was cachectic when he presented to hospital. Read More

Clin Sports Med 2021 Jul;40(3):471-490

Department of Orthopaedic Surgery, University of Virginia, PO Box 800159, Charlottesville, VA 22908, USA. Electronic address:

Repetitive stress on the lumbosacral spine during sporting activity places the athletic patient at risk of developing symptomatic pars defect. Clinical history, physical examination, and diagnostic imaging are important to distinguish spondylolysis from other causes of lower back pain. Early pars stress reaction can be identified with advanced imaging, before the development of cortical fracture or vertebral slip progression to spondylolisthesis. Read More

J Int Med Res 2021 May;49(5):3000605211015559

Department of Orthopaedic Surgery, 183174Fukushima Medical University School of Medicine, Fukushima City, Fukushima, Japan.

The incidence of lumbar spondylolysis is affected by sex, race, and congenital abnormalities. These differences suggest a genetic component to the etiology of spondylolysis. However, no definitive evidence has been presented regarding the inheritance of lumbar spondylolysis. Read More

Int J Environ Res Public Health 2021 04 12;18(8). Epub 2021 Apr 12.

Department of Physical Medicine & Rehabilitation, College of Medicine, Kyung Hee University, Seoul 02447, Korea.

The objective of this study was to assess the cross-sectional areas (CSA) of lumbar paraspinal muscles and their fatty degeneration in adults with degenerative lumbar spondylolisthesis (DLS) diagnosed with chronic radiculopathy, compare them with those of the same age- and sex-related groups with radiculopathy, and evaluate their correlations and the changes observed on magnetic resonance imaging (MRI). This retrospective study included 62 female patients aged 65-85 years, who were diagnosed with lumbar polyradiculopathy. The patients were divided into two groups: 30 patients with spondylolisthesis and 32 patients without spondylolisthesis. Read More

Int J Mol Sci 2021 Mar 31;22(7). Epub 2021 Mar 31.

Department of Surgery, Division of Neurosurgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan.

Transforaminal lumber interbody fusion (TLIF) is the last resort to address the lumber degenerative disorders such as spondylolisthesis, causing lower back pain. The current surgical intervention for these abnormalities includes open TLIF. However, in recent years, minimally invasive TLIF (MIS-TLIF) has gained a high momentum, as it could minimize the risk of infection, blood loss, and post-operative complications pertaining to fusion surgery. Read More

BMC Musculoskelet Disord 2021 Feb 23;22(1):218. Epub 2021 Feb 23.

Department of Spine Surgery, Beijing Jishuitan Hospital, No. 31, Xinjiekou East Street, Xicheng District, Beijing, 100035, People's Republic of China.

Background: For patients with degenerative spondylolisthesis, whether additional posterior fixation can further improve segmental alignment is unknown, compared with stand-alone cage insertion in oblique lumbar interbody fusion (OLIF) procedure. The aim of this study was to compare changes of the radiographical segmental alignment following stand-alone cage insertion and additional posterior fixation in the same procedure setting of OLIF for patients with degenerative spondylolisthesis.

Methods: A retrospective observational study. Read More

Neurosurgery 2021 02;88(3):E246-E247

Goodman Campbell Brain and Spine, Indianapolis, Indiana.

BMC Musculoskelet Disord 2021 Jan 13;22(1):75. Epub 2021 Jan 13.

Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.

Background: If bone union is expected, conservative treatment is generally selected for lumbar spondylolysis. However, sometimes conservative treatments are unsuccessful. We sought to determine the factors associated with failure of bony union in acute unilateral lumbar spondylolysis with bone marrow edema including contralateral pseudarthrosis. Read More

BMC Musculoskelet Disord 2021 Jan 5;22(1):17. Epub 2021 Jan 5.

Department of Orthopaedic Surgery, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-8510, Japan.

Background: Utilization of a cage with a large footprint in lateral lumbar interbody fusion (LLIF) for the treatment of spondylolisthesis leads to a high fusion rate and neurological improvement owing to the indirect decompression effect and excellent alignment correction. However, if an interbody space is too narrow for insertion of an LLIF cage for cases of spondylolisthesis of Meyerding grade II or higher, LLIF cannot be used. Therefore, we developed a novel strategy, LLIF after reduction by the percutaneous pedicle screw (PPS) insertion system in the lateral position (LIFARL), for surgeons to perform accurate and safe LLIF with PPS in patients with such pathology. Read More

Spine (Phila Pa 1976) 2020 Dec 31;Publish Ahead of Print. Epub 2020 Dec 31.

Forest Orthopaedic Sports Clinic, Japan Graduate School of Health Sciences, Gunma University, Japan School of Physiotherapy, University of Otago, New Zealand.

Study Design: Case control study.

Objective: To establish an algorithm to distinguish acute lumbar spondylolysis (LS) from non-specific low back pain (NSLBP) among patients in junior high school by classification and regression tree (CART) analysis.

Summary Of Background Data: Rapid identification of acute LS is important because delayed diagnosis may result in pseudarthrosis in the pars interarticularis. Read More

Int Orthop 2021 04 4;45(4):997-1001. Epub 2021 Jan 4.

Department of Radiology and Medical Imaging, University of Medicine and Pharmacy "Victor Babes", Timișoara, Romania.

Purpose: Long time recognized as a cause of lumbar stenosis, degenerative spondylolisthesis has an evolution in interrelation with sagittal balance. This study aimed to assess the role of ALIF in correcting the sagittal balance in patients with degenerative spondylolisthesis.

Material And Methods: Twenty patients aged between 47 and 70 years were operated between July 2011 and September 2014 for degenerative spondylolisthesis by ALIF. Read More

Spine (Phila Pa 1976) 2021 Jan;46(2):122-128

Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation.

Study Design: Cross-sectional study.

Objective: The aim of this study was to evaluate the actual prevalence of degenerative spinal changes and their association with age in a cohort of professional soccer players.

Summary Of Background Data: Presently, there are data that athletes have more degenerative changes than nonathletes; however, the research examining the prevalence of degenerative spinal conditions among professional elite soccer players is scarce. Read More

J Back Musculoskelet Rehabil 2021 ;34(1):131-137

Occupational Medicine Department, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Background: Low back pain (LBP) is a common health condition and the leading cause of activity limitation and absenteeism in most parts of the world. One-fifth of patients with LBP develop chronic pain disability.

Objective: This study investigated the disability levels in patients with different types of lumbar spinal disorders. Read More

Neurosurgery 2021 01;88(2):322-331

Department of Spine Surgery, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, China.

Background: Lumbosacral spondylolisthesis-induced scoliosis is a rare clinical entity. Sagittal reconstruction and the coronal curve evolution after surgery for spondylolisthesis have not been investigated in depth.

Objective: To compare the curve characteristics between sciatic scoliosis and olisthetic scoliosis and to further investigate the effects of lumbosacral transforaminal lumbar interbody fusion (TLIF) on scoliosis evolution. Read More

Zhongguo Gu Shang 2020 Sep;33(9):862-6

Department of Traumatology and Orthopaedics, Yijishan Hospital, Wannan Medical College, Wuhu 241001, Anhui, China.

Objective: To analyze the characteristics of lumbar spine-pelvic structure in degenerative lumbar spondylolisthesis and its significance in degenerative lumbar spondylolisthesis(DLS).

Methods: The clinical data of 45 patients with simple degenerative L-segment lumbar spondylolisthesis (spondylolisthesis group) admitted from April 2015 to January 2017 were retrospectively analyzed, which were compared with 50 healthy people with complete physical examination data in the same period(control group). Statistical analysis of the lumbar spine-pelvic structure parameters of the subjects through imaging data was performed to analyze the characteristics of the spine-pelvis of DLS patients. Read More

Unfallchirurg 2020 Nov;123(11):890-895

Klinik für Orthopädie, Unfall- und Handchirurgie, Helios Klinikum Krefeld, Lutherplatz 40, 47805, Krefeld, Deutschland.

This article reports on the case of a rare combination injury of a C3 pelvic ring fracture (Malgaigne's fracture) and simultaneous unstable traumatic spondylolisthesis (Meyerding grade 2) of the lumbosacral spine. The patient had pronounced neurological deficits of the lower extremities and tearing of the thecal sac. The selected primary and secondary surgical treatment algorithm of the polytraumatized patient as well as the course are described and critically discussed on the basis of the sparsely available literature. Read More

Clin Interv Aging 2020 21;15:1213-1219. Epub 2020 Jul 21.

Orthopaedic Department, Chengde Medical University Affiliated Hospital, Chengde 067000, Hebei, People's Republic of China.

Purpose: Percutaneous transforaminal endoscopic decompression (PTED) is an ultra-minimally invasive surgical option for patients that does not involve the same amount of destabilizing facet joint removal as a traditional laminectomy. The objective of this study was to describe the procedure of PTED under local anesthesia for geriatric patients with central spinal stenosis and degenerative lumbar spondylolisthesis (CSS-DLS).

Materials And Methods: From January 2016 to December 2018, 30 consecutive geriatric patients who underwent surgery for single-level CSS-DLS were retrospectively reviewed. Read More

Neurosurgery 2020 10;87(5):E609-E610

Department of Neurological Surgery University of California San Francisco San Francisco, California.

Neurosurgery 2020 10;87(5):E608

Department of Neurosurgery Sanjay Gandhi Post Graduate Institute of Medical Sciences Lucknow, India.

Eur Spine J 2020 10 31;29(10):2465-2469. Epub 2020 Jul 31.

Department of Orthopaedic Surgery, University of Tsukuba (Tsukuba Pediatric Orthopaedic Group), Tsukuba City, Ibaraki, Japan.

Purpose: We often encounter elementary school-aged children with fresh lumbar spondylolysis and non-union of bone. They may have factors that impede healing, and treatment outcomes need improvement. The purpose of this study was to investigate elementary school-aged patients with fresh lumbar spondylolysis and to identify characteristics that can aid in prompt diagnosis and proper therapy. Read More

Clin Orthop Relat Res 2020 08;478(8):1889-1891

C. Reitman, Professor, Department of Orthopaedics and Physical Medicine, Medical University of South Carolina, Charleston, SC, USA.

BMC Musculoskelet Disord 2020 Jul 22;21(1):483. Epub 2020 Jul 22.

Department of Spinal Surgery, Nanfang Hospital, Southern Medical University, 1838 North Guangzhou Avenue, Guangzhou, China.

Background: This study was conducted to compare differences in imaging features and clinical symptoms between patients with single-level isthmic spondylolisthesis (IS) at L4 and at L5 and to investigate the correlation between imaging and clinical parameters.

Methods: This cross-sectional study evaluated patients with single-level IS who were enrolled between June 2011 and June 2018. A total of 139 patients, 44 in the L4 IS group and 95 in the L5 IS group, met the study criteria and were included. Read More

J Orthop Surg Res 2020 Jul 6;15(1):243. Epub 2020 Jul 6.

Department of Orthopaedics, Peking University Third Hospital, No.49 Huayuan Bei Road, Beijing, 100191, China.

Background: Although pelvic and related parameters have been well stated in lumbar developmental spondylolisthesis, cervical sagittal alignment in these patients is poorly studied, especially in high dysplastic developmental spondylolisthesis (HDDS). The purpose of this study is to investigate the sagittal alignment of the cervical spine in HDDS and how the cervical spine responds to reduction of spondylolisthesis.

Methods: Thirty-three adolescent patients with lumbar developmental spondylolisthesis who received preoperative and postoperative whole-spine x-rays were reviewed. Read More

Zhongguo Gu Shang 2019 Oct;32(10):965-970

Department of Orthopaedics, Tianyou Hospital Affiliated to Wuhan University of Science and Technology, Wuhan 430000, Hubei, China;

Objective: To compare the clinical results between the Wiltse approach and traditional approach in lumbar fusion.

Methods: The clinical data of 70 patients with lumbar disc herniation or lumbar spondylolisthesis within Meyerding II degree who underwent lumbar fusion surgery from May 2016 to May 2017 were retrospectively analyzed. According to the surgical approach, the patients were divided into Wiltse approach group and traditional approach group. Read More

Oper Orthop Traumatol 2020 Jun 28;32(3):192-199. Epub 2020 May 28.

Wirbelsäulenzentrum, Schön Klinik München Harlaching, Akademisches Lehrkrankenhaus und Institut für Wirbelsäulenforschung der PMU Salzburg, Harlachinger Str. 51, 81547, München, Deutschland.

Objective: Stable interbody fusion of the lumbosacral segment via an anterior retroperitoneal approach using an interbody spacer as an anterior stand-alone device which is fixed with four locking screws.

Indications: Degenerative disc disease without instability or deformity; adjacent segment degeneration; pseudarthrosis.

Contraindications: Translational instabilities as in spondylolisthesis at the index segment; deformities; steep sacral slope. Read More

Spine (Phila Pa 1976) 2020 Oct;45(20):1451-1458

Computational Neurosciences Outcomes Center, Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

Study Design: Retrospective cohort study.

Objective: The primary objective of our study was to evaluate the surgical outcomes and complications of minimally invasive surgery (MIS) versus open surgery in the management of intermediate to high grade spondylolisthesis, and secondarily to compare the outcomes following MIS in-situ fusion versus MIS reduction and open in-situ fusion versus open reduction subgroups.

Summary Of Background Data: High-grade spondylolisthesis is a relatively rare spine pathology with unknown prevalence. Read More

Clin Neurol Neurosurg 2020 07 16;194:105918. Epub 2020 May 16.

Orthopaedic Department, Chengde Medical University Affiliated Hospital, Chengde 067000, Hebei, China. Electronic address:

Objectives: Percutaneous transforaminal endoscopic decompression (PTED) under local anesthesia is rarely performed for lumbar spinal stenosis (LSS) with degenerative lumbar spondylolisthesis (DLS) because of the limited field of vision, inherent instability, etc. The objective of this study was to describe the procedure of the PTED technique and to demonstrate the early clinical outcomes.

Patients And Methods: From January 2017 to January 2019, 40 consecutive patients aged 60 and older were diagnosed with LSS with DLS in our institution and underwent PTED. Read More

World Neurosurg 2020 10 17;142:e18-e31. Epub 2020 May 17.

Department of Orthopedics, Changzheng Hospital, Second Affiliated Hospital of Second Military Medical University, Shanghai, People's Republic of China. Electronic address:

Objective: To propose and validate a novel and comprehensive classification of lumbosacral spondylolysis and spondylolisthesis in the pediatric population according to surgical managements.

Methods: Cases of pediatric lumbosacral (L5/S1 level) spondylolysis and spondylolisthesis were reviewed. Lumbar Japanese Orthopedics Association score, health-related quality of life, spondylolisthesis, lumbosacral disc degeneration, and dysplastic features were included for evaluation of outcomes after surgery. Read More