1,326 results match your criteria Lumbosacral Radiculopathy


Neurogenic calf amyotrophy with CK elevation by entrapment radiculopathy; clinical, radiological, and pathological analyses of 18 cases.

J Neurol 2020 Jul 3. Epub 2020 Jul 3.

Department of Neurology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma, 371-8511, Japan.

Objective: To characterize the clinical, radiological, and pathological manifestations of 18 cases showing neurogenic calf amyotrophy with creatine kinase (CK) elevation by entrapment radiculopathy (NCACKEER).

Methods: We retrospectively reviewed and evaluated the medical records of patients who complained of weakness or atrophy of the calf muscles in our department between 2004 and 2019. We identified 18 cases fulfilling the proposed criteria of NCACKEER. Read More

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http://dx.doi.org/10.1007/s00415-020-10021-3DOI Listing

[General hydro galvanic baths in the treatment of patients with lumbosacral radiculopathy].

Vopr Kurortol Fizioter Lech Fiz Kult 2020 ;97(3):35-42

Scientific practical center of medical and social rehabilitation named after L.I. Shvetsova, Moscow, Russia.

Introduction: Hydrogalvanic baths are a hydrotherapy method based on the combined effect of electric current and fresh water on the body.

Aim Of Study: Scientific evidence and evaluation of the effectiveness of use of general hydrogalvanic baths in the treatment of patients with lumbosacral radiculopathy with the background of degenerative spinal disorder.

Materials And Methods: A randomized comparative clinical trial included 84 patients. Read More

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http://dx.doi.org/10.17116/kurort20209703135DOI Listing
January 2020

Evaluation of Persons with Suspected Lumbosacral and Cervical Radiculopathy: Electrodiagnostic Assessment and Implications for Treatment and Outcomes (PART II).

Muscle Nerve 2020 Jun 21. Epub 2020 Jun 21.

Clinical Director, Musculoskeletal Spine & Sports Rehabilitation Medicine, MossRehab, Einstein Spine Institute, Co-Chair, Albert Einstein Healthcare Network, Clinical Associate Professor of Rehabilitation Medicine, Thomas Jefferson University.

The electrodiagnostic (EDX) examination with needle electromyography (EMG) is the most important means of testing for radiculopathy. This test has modest sensitivity but high specificity and complements imaging of the spine. In this second of a two-part review, the implications of electrodiagnostic findings for diagnosis and clinical management of persons with radiculopathy are reviewed. Read More

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http://dx.doi.org/10.1002/mus.27008DOI Listing

Evaluation of Persons with Suspected Lumbosacral and Cervical Radiculopathy: Electrodiagnostic Assessment and Implications for Treatment and Outcomes (PART I).

Muscle Nerve 2020 Jun 17. Epub 2020 Jun 17.

Clinical Director, Musculoskeletal Spine & Sports Rehabilitation Medicine, MossRehab Einstein Spine Institute, Co-Chair, Albert Einstein Healthcare Network, Clinical Associate Professor of Rehabilitation Medicine, Thomas Jefferson University, USA.

Persons with back, neck, and limb symptoms constitute a major referral population to specialists in electrodiagnostic (EDX) medicine. The evaluation of these patients involves consideration of both the common and less common disorders. The EDX examination with needle electromyography (EMG) is the most important means of testing for radiculopathy. Read More

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http://dx.doi.org/10.1002/mus.26997DOI Listing

Etiology of Lumbosacral Radiculoplexopathy: Sacral Insufficiency Fracture on Magnetic Resonance Imaging.

HSS J 2020 Jul 6;16(2):126-129. Epub 2020 Feb 6.

Department of Radiology and Imaging, Hospital for Special Surgery, 535 E. 70th St., New York, NY 10021 USA.

Background: Sacral insufficiency fracture (SIF) can cause lumbosacral radiculoplexopathy (LSRP) and is probably under-recognized. Symptoms may include nonspecific lumbar spine or buttock pain that is exacerbated by physical activity and alleviated with rest. The frequency of LSRP secondary to SIF has not been reported. Read More

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http://dx.doi.org/10.1007/s11420-020-09750-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253557PMC

Lumbosacral Radiculopathy as the Clinical Presentation of Neurocysticercosis.

Am J Trop Med Hyg 2020 Jun;102(6):1166-1167

Department of Radiology, Hospital Universitario 12 de Octubre, Madrid, Spain.

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http://dx.doi.org/10.4269/ajtmh.19-0757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253111PMC

Balance Ability in Low Back Pain Patients With Lumbosacral Radiculopathy Evaluated With Tetrax: A Matched Case-Control Study.

Ann Rehabil Med 2020 Jun 29;44(3):195-202. Epub 2020 May 29.

Department of Rehabilitation Medicine, Bundang Jesaeng General Hospital, Seongnam, Korea.

Objective: To compare postural balance ability in patients with low back pain between groups with and without lumbosacral radiculopathy.

Methods: Patients who were referred for electromyography because of low back pain during the period from April 2017 through June 2018 were chosen as subjects. They were divided into groups with and without lumbosacral radiculopathy based on the results of electromyography. Read More

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http://dx.doi.org/10.5535/arm.19101DOI Listing

40% reoperation rate in adolescents with spondylolisthesis.

Spine Deform 2020 May 6. Epub 2020 May 6.

Children's Orthopaedic Center, Children's Hospital Los Angeles, 4650 Sunset Blvd, Mailstop #69, Los Angeles, CA, 90027, USA.

Study Design: Multicenter retrospective.

Objective: To determine the long-term complication rate associated with surgical treatment of spondylolisthesis in adolescents. There is limited information on the complication rate associated with posterior spinal fusion (PSF) of spondylolisthesis in the pediatric and adolescent population. Read More

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http://dx.doi.org/10.1007/s43390-020-00121-5DOI Listing

Evaluation of L7-S1 nerve root pathology with low-field MRI in dogs with lumbosacral foraminal stenosis.

Vet Surg 2020 Jul 27;49(5):947-957. Epub 2020 Apr 27.

Clinic of Diagnostic Imaging, Vetsuisse Faculty, University of Zürich, Switzerland.

Objective: To describe low-field MRI findings associated with lumbosacral foraminal stenosis and radiculopathy and correlate these with clinical signs.

Study Design: Retrospective study.

Animals: Client-owned dogs (n = 240) that underwent a clinical examination and standardized MRI protocol of the lumbosacral junction. Read More

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http://dx.doi.org/10.1111/vsu.13424DOI Listing

Evaluation of Treatment Patterns and Direct Costs Associated with the Management of Neuropathic Pain.

Pain Res Manag 2020 30;2020:9353940. Epub 2020 Mar 30.

Pfizer S.A.S, Bogotá, Colombia.

Background: Neuropathic pain has a prevalence of 2-17% in the general population. Diagnosis and treatment of neuropathic pain are not fully described in different populations. The aim was to determine the treatment patterns and direct costs of care associated with the management of neuropathic pain from the onset of the first symptom to up to two years after diagnosis. Read More

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http://dx.doi.org/10.1155/2020/9353940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149442PMC

Lumbar Radicular Pain Response to First Injection with Non-particulate Steroid.

Cureus 2020 Feb 26;12(2):e7104. Epub 2020 Feb 26.

Molecular Medicine, Physical Medicine and Rehabilitation, The Feinstein Institute for Medical Research/Hofstra Northwell School of Medicine, Manhasset, USA.

Introduction Recent studies on the use of transforaminal epidural steroid injection (TFESI) to treat lumbar radicular pain have highlighted controversies pertaining to the choice of corticosteroid agent utilized in lumbosacral TFESI, in terms of both safety and efficacy. The primary objective was to characterize the radicular pain response after a first transforaminal injection with dexamethasone. The secondary objective was to document the response of those who failed to respond to a dexamethasone injection when particulate steroid was utilized for a second injection. Read More

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http://dx.doi.org/10.7759/cureus.7104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100620PMC
February 2020

Comparing pain relief and functional improvement between methylprednisolone and dexamethasone lumbosacral transforaminal epidural steroid injections: a self-controlled study.

Korean J Pain 2020 Apr;33(2):192-198

Department of Physical Medicine & Rehabilitation, Medical College of Wisconsin, Milwaukee, WI, USA.

Background: Previous studies have shown varying results between lumbosacral transforaminal epidural steroid injections (TFESIs) performed with particulate versus non-particulate corticosteroids. The purpose of this study was to investigate the difference in pain relief and functional improvement between particulate and non-particulate lumbosacral TFESIs in patients who had undergone both injections, sequentially.

Methods: This was a self-controlled, retrospective study of 20 patients who underwent both a methylprednisolone and a dexamethasone TFESI to the same vertebral level and side. Read More

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http://dx.doi.org/10.3344/kjp.2020.33.2.192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136301PMC

Motor unit number index in quantitatively assessing motor root lesions and monitoring treatment outcomes in patients with lumbosacral radiculopathy.

Muscle Nerve 2020 Jun 14;61(6):759-766. Epub 2020 Mar 14.

Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai, China.

Introduction: We investigated the feasibility of motor unit number index (MUNIX) in quantitatively assessing motor root lesions and tracking different treatment outcomes in lumbosacral radiculopathy (LR).

Methods: Bilateral MUNIX was recorded from the abductor hallucis, extensor digitorum brevis, and tibialis anterior in 44 normal controls and 108 patients with LR, and this was repeated approximately 12 months after treatment in 60 patients with LR.

Results: More abnormalities were observed when side-to-side differences of MUNIX measurements were used to evaluate LR (P < . Read More

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http://dx.doi.org/10.1002/mus.26854DOI Listing

Tissue distribution of S-metabolically labeled neublastin (BG00010) in rats.

J Pharm Biomed Anal 2020 May 6;184:113154. Epub 2020 Feb 6.

Biogen, Cambridge, MA 02142, United States.

Neublastin (NBN) is a neurotrophic growth factor that promotes the survival and regenerative properties of nociceptive neurons and has been tested in clinical trials as a treatment for neuropathic pain in individuals with sciatica and painful lumbosacral radiculopathy. Like many low molecular weight heparin binding proteins, NBN is rapidly cleared from the blood following systemic administration. To explore ADME properties of NBN in rats, we used metabolically S-labeled NBN following IV and SC administration quantifying counts and intact protein in kidney, liver, brain, serum, and urine at 5 min, 8 h, 24 h and 48 h, and biodistribution in whole body carcasses by QWBA at 2, 8, 48, 96, and 168 h post dose. Read More

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http://dx.doi.org/10.1016/j.jpba.2020.113154DOI Listing

Electrodiagnostic characteristics of upper lumbar stenosis: Discrepancy between neurological and structural levels.

Muscle Nerve 2020 05 7;61(5):580-586. Epub 2020 Mar 7.

Department of Rehabilitation Medicine, Seoul National University Hospital, Seoul, Republic of Korea.

Background: Radiculopathies caused by spinal stenosis in the upper lumbar spinal canal (L1/2, L2/3, L3/4) have not been comprehensively investigated.

Methods: This retrospective study reviewed 14 patients from a tertiary hospital outpatient clinic. The inclusion criteria were upper lumbar stenosis seen on MRI and radiculopathies with active denervation confirmed on electromyography. Read More

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http://dx.doi.org/10.1002/mus.26844DOI Listing

Correlation between Findings in Physical Examination, Magnetic Resonance Imaging, and Nerve Conduction Studies in Lumbosacral Radiculopathy Caused by Lumbar Intervertebral Disc Herniation.

Adv Orthop 2020 24;2020:9719813. Epub 2020 Jan 24.

Department of Orthopaedics Surgery and Traumatology, Faculty of Medicine, University of Khartoum, Khartoum, Sudan.

Purpose: The aim of this study was to find out the correlation between magnetic resonance imaging (MRI) and nerve conduction studies' (NCS) findings in patients with lumbosacral radiculopathy caused by lumbar intervertebral disc herniation. In addition, the study aimed at finding the correlation between the clinical manifestations of lumbosacral radiculopathy and both MRI and NCS. . Read More

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http://dx.doi.org/10.1155/2020/9719813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008266PMC
January 2020

On the Outcome of Pulsed Radiofrequency Treatment According to Electrodiagnosis in Patients with Intractable Lumbosacral Radicular Pain.

Authors:
Min Cheol Chang

Pain Med 2020 02;21(2):432-433

Spine Center, Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Taegu, Republic of Korea.

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http://dx.doi.org/10.1093/pm/pnz229DOI Listing
February 2020

A quantitative and clinical evaluation of nerve roots in lumbosacral radiculopathy using diffusion tensor imaging.

Jpn J Radiol 2020 Mar 21;38(3):222-230. Epub 2019 Dec 21.

The Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, People's Republic of China.

Purpose: This study aimed to investigate the relationship between the fractional anisotropy (FA) values of compressed nerves derived in diffusion tensor imaging (DTI) and the corresponding clinical symptoms for quantitative and clinical evaluation in patients with lumbosacral radiculopathy.

Methods: Thirty-six patients and ten volunteers participated in the study and measured with DTI. The resultant FA values for L5-S1 lumbar nerve roots were calculated at three sub-regions. Read More

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http://dx.doi.org/10.1007/s11604-019-00913-4DOI Listing

A Video of Ultrasound-Guided S1 Transforaminal Epidural Injection Using Color Doppler: Technical Reports.

Pain Pract 2020 04 9;20(4):396-398. Epub 2019 Dec 9.

Department of Rehabilitation Medicine, Daegu Fatima Hospital, Daegu, South Korea.

Lumbosacral radicular pain with or without radiculopathy is a fairly common clinical condition. In such cases, lumbosacral transforaminal epidural injection (TFEI) is one of the most commonly performed interventions. Recent studies have explored the effectiveness of ultrasound (US)-guided lumbosacral TFEI. Read More

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http://dx.doi.org/10.1111/papr.12858DOI Listing

A rare case of parasagittal meningioma causing isolated foot drop: case report and review of the literature.

Acta Neurol Belg 2019 Nov 30. Epub 2019 Nov 30.

Department of Neurology, Clinical Hospital Centre Zagreb, Kišpatićeva 12, 10000, Zagreb, Croatia.

Foot drop represents a very common reason for a neurologist referral and is often first seen in emergency departments or by a general practitioner. This condition is defined as weakness of ankle dorsiflexion (mainly through tibialis anterior muscle weakness). The most common causes include lower motor neuron lesion, with L4-L5 radiculopathy and peroneal neuropathy being the most frequent ones. Read More

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http://dx.doi.org/10.1007/s13760-019-01255-8DOI Listing
November 2019

Extraordinary features of the intraspinal extradural and intradural nerve root courses.

Neuro Endocrinol Lett 2019 Oct 8;40(Suppl1):29-36. Epub 2019 Oct 8.

Department of Neurosurgery, Faculty of Medicine, University Hospital, Comenius University, Bratislava, Slovakia.

Objectives: Very few studies have reported occasional intradural and extradural communications between adjacent nerve roots. These studies mostly focus on lumbosacral regions followed by cervical regions, and rarely in the thoracic region.

Design: The aim of this work is to point out some extraordinary extradural and intradural features of the intraspinal nerve root courses and their possible participation in radiculopathy. Read More

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October 2019

Transforaminal Versus Lateral Parasagittal Versus Midline Interlaminar Lumbar Epidural Steroid Injection for Management of Unilateral Radicular Lumbar Pain: A Randomized Double-Blind Trial.

Pain Physician 2019 11;22(6):561-573

Department of Endocrinology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Background: Epidural steroid injections (ESIs) are commonly used for management of lumbosacral radicular pain. Midline interlaminar (MIL) or transforaminal (TF) routes are commonly used. The TF route, although associated with higher delivery of drug to the ventral epidural space, has serious complications including spinal cord injury and permanent paralysis reported in literature. Read More

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November 2019

Motor lumbosacral radiculopathy in HIV-infected patients.

South Afr J HIV Med 2019 28;20(1):992. Epub 2019 Oct 28.

Department of Neurology, University of KwaZulu-Natal, Durban, South Africa.

Background: This study is a review of the clinical findings and treatment outcome of 11 HIV-infected patients with motor lumbosacral radiculopathy.

Objectives: To describe the clinical, laboratory, electrophysiological features and treatment outcome in HIV-infected motor lumbosacral radiculopathy which is a rare manifestation of HIV.

Method: A retrospective review of HIV-infected patients with motor lumbosacral radiculopathy was performed at Inkosi Albert Luthuli Central Hospital (IALCH), Durban, South Africa between 2010 and 2015. Read More

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http://dx.doi.org/10.4102/sajhivmed.v20i1.992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852262PMC
October 2019

Tibial motor and sural electrophysiological relationship in subjects without and patients with mild axonal peripheral neuropathy.

Acta Neurol Belg 2020 Jun 4;120(3):677-680. Epub 2019 Nov 4.

Academic Department of Neurosciences, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.

The distal motor fibers of the tibial and sural nerves are predominantly derived from the S1 root. We aimed to describe the electrophysiological relationship of these two nerves. Clinical, radiological and neurophysiological data of patients with mild, length-dependent, peripheral neuropathy (PN) and subjects without PN were retrospectively collected and analyzed. Read More

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http://dx.doi.org/10.1007/s13760-019-01233-0DOI Listing

Clinical effectiveness of caudal epidural pulsed radiofrequency stimulation in managing refractory chronic leg pain in patients with postlumbar surgery syndrome.

J Back Musculoskelet Rehabil 2020 ;33(3):523-528

Background And Objective: We evaluated the effect of caudal epidural pulsed radiofrequency stimulation in patients with chronic lumbosacral radicular pain due to postlumbar surgery syndrome who were unresponsive to at least two epidural steroid injections through the interlaminar, transforaminal, or caudal route.

Methods: We recruited 25 patients with chronic persistent radicular pain in one or both legs (⩾ 4 on the Numeric Rating Scale [NRS]) despite spinal surgery. They were unresponsive to at least two epidural steroid injections. Read More

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http://dx.doi.org/10.3233/BMR-170981DOI Listing
January 2020
2 Reads

Isolated asymptomatic atrophy of the extensor digitorum brevis muscle.

Muscle Nerve 2020 01 17;61(1):E10-E11. Epub 2019 Oct 17.

Department of Neurology, Ibn Sina Hospital, POB 25427, Sabah Health Area, Safat, Kuwait.

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http://dx.doi.org/10.1002/mus.26732DOI Listing
January 2020
4 Reads
2.283 Impact Factor

The effect of needle tip position on the analgesic efficacy of pulsed radiofrequency treatment in patients with chronic lumbar radicular pain: a retrospective observational study.

Korean J Pain 2019 Oct;32(4):280-285

Department of Anesthesiology and Pain Medicine, Ewha Womans University Mokdong Hospital, School of Medicine, Ewha Womans University, Seoul, Korea.

Background: Pulsed radiofrequency (PRF) is a treatment modality that alleviates radicular pain by intermittently applying high-frequency currents adjacent to the dorsal root ganglion. There has been no comparative study on analgesic effect according to the position of the needle tip in PRF treatment. The objective of this study is to evaluate the clinical outcomes of PRF according to the needle tip position. Read More

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http://dx.doi.org/10.3344/kjp.2019.32.4.280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813899PMC
October 2019
3 Reads

The ambiguity of sciatica as a clinical diagnosis: A case series.

J Am Assoc Nurse Pract 2019 Sep 24. Epub 2019 Sep 24.

Logan University Health Centers-Integrative Clinics, Chesterfield, Missouri.

Sciatica as a clinical diagnosis is nonspecific. A diagnosis of sciatica is typically used as a synonym for lumbosacral radiculopathy. However, the differential for combined low back and leg pain is broad, and the etiology can be one several different conditions. Read More

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http://dx.doi.org/10.1097/JXX.0000000000000288DOI Listing
September 2019
3 Reads

A Staged Treatment of Symptomatic Lumbar Intraspinal Synovial Cysts.

Pain Physician 2019 09;22(5):E451-E456

Department of Anesthesia and Pain Medicine, School of Medicine, Pusan National University, Yangsan, Korea.

Background: Lumbar intraspinal synovial cyst (LISC) refers to a cyst that arises from the zygapophyseal joint capsule of the lumbar spine and contains serous or gelatinous fluid. In cases of LISCs resistant to conservative treatments, various minimally invasive percutaneous spinal techniques (MIPSTs) may be applied prior to open surgery.

Objectives: The outcomes of 3-staged MIPSTs for the treatment of symptomatic LISCs resistant to conservative treatments were evaluated. Read More

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September 2019
2 Reads

Is fluoroscopy-guided percutaneous rupture of facet cyst an alternative to surgery? A case report.

Turk J Phys Med Rehabil 2018 Dec 4;64(4):362-365. Epub 2018 Nov 4.

Department of Pain Medicine, Ochsner Baptist Medical Center, New Orleans, USA.

Lumbar intraspinal synovial cysts (LISCs) are rare cause of the lumbosacral radicular syndrome. Fluoroscopy-guided percutaneous cyst rupture (PCR) is an option in the treatment. This report introduces long-term symptom relief after fluoroscopy-guided PCR of LISC. Read More

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http://dx.doi.org/10.5606/tftrd.2018.2253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648033PMC
December 2018
2 Reads

Dorsal root ganglion pulsed radiofrequency treatment for chronic cervical radicular pain: a retrospective review of outcomes in fifty-nine cases.

Ir J Med Sci 2020 Feb 22;189(1):299-303. Epub 2019 Aug 22.

Department of Pain Medicine, St James's Hospital, James Street, Dublin 8, Ireland.

Pulsed radiofrequency treatment adjacent to the cervical dorsal root ganglion is used to treat persistent cervical radicular pain that has not responded to conservative therapies. This technique has gained popularity in years for both cervical and lumbosacral radicular pain. The evidence to support its use is still evolving. Read More

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http://link.springer.com/10.1007/s11845-019-02087-4
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http://dx.doi.org/10.1007/s11845-019-02087-4DOI Listing
February 2020
3 Reads

Electrodiagnostic findings in dogs with apparently painful lumbosacral foraminal stenosis.

J Vet Intern Med 2019 Sep 5;33(5):2167-2174. Epub 2019 Aug 5.

Department of Small Animal Clinical Sciences, Texas A&M University, College Station, Texas.

Background: Development of management strategies for lumbosacral stenosis in dogs is hampered by the lack of objective diagnostic criteria and outcome measures.

Objective: To explore the suitability of electrodiagnostic tests as ancillary diagnostic aids, inclusion criteria, or outcome measures.

Sample Population: Sixty-one client-owned dogs with clinical signs of lumbosacral foraminal stenosis. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jvim.15589
Publisher Site
http://dx.doi.org/10.1111/jvim.15589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766485PMC
September 2019
19 Reads

Evaluation of clinical efficacy of silver-needle warm acupuncture in treating adults with acute low back pain due to lumbosacral disc herniation: study protocol for a randomized controlled trial.

Trials 2019 Jul 31;20(1):470. Epub 2019 Jul 31.

Shanghai Pudong New Area Hospital of Traditional Chinese Medicine, 399 Pingchuan Road, Pudong New Area, Shanghai, 201299, China.

Background: As a common cause of low back pain, lumbosacral disc herniation (LDH) is usually dealt with using non-surgical interventions. In the face of concerns about prescription opioid abuse, alternative and complementary treatments may be promising, among which silver-needle warm acupuncture is considered as an upgrading option for its potential anti-inflammatory and strong analgesic effect for patients with chronic pain. In this proposed study, we aim to assess its clinical efficacy in comparison with conventional stainless steel filiform-needle warm acupuncture. Read More

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http://dx.doi.org/10.1186/s13063-019-3566-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668190PMC
July 2019
2 Reads

Parallels between lumbosacral radiculopathy and complex regional pain syndrome: α1-adrenoceptor upregulation, reduced dermal nerve fibre density, and hemisensory disturbances in postsurgical sciatica.

Pain 2019 08;160(8):1891-1900

Psychology Unit, College of Science, Health, Engineering and Education, Murdoch University, Perth, Australia.

Residual lower-limb pain after low back surgery (postsurgical sciatica) and complex regional pain syndrome (CRPS) involving a lower limb are separate conditions but may share some mechanisms (eg, tissue inflammation, neuroimmune disturbances, and central neuroplasticity). As adrenergically evoked pain contributes, in part, to CRPS, whether an adrenergic mechanism also contributes to postsurgical sciatica was investigated in this study. Immunohistochemistry was used to identify α1-adrenoceptors (α1-AR) on nerve fibres and other targets in the affected and contralateral skin of 25 patients with postsurgical sciatica, and α1-AR expression was investigated in relation to pain and pinprick hyperalgesia after intradermal injection of the α1-AR agonist phenylephrine. Read More

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http://dx.doi.org/10.1097/j.pain.0000000000001574DOI Listing
August 2019
3 Reads

Relationship Between Cauda Equina Conduction Time and Type of Neurogenic Intermittent Claudication due to Lumbar Spinal Stenosis.

J Clin Neurophysiol 2020 Jan;37(1):62-67

Department of Orthopaedic Surgery, Yamaguchi Rosai Hospital, Yamaguchi, Japan.

Introduction: This study investigated whether the prolongation of the cauda equina conduction time (CECT) was related to the type of neurogenic intermittent claudication due to lumbar spinal stenosis.

Methods: In total, 149 patients who underwent surgery due to lumbar spinal stenosis with neurogenic intermittent claudication were classified into three groups as follows: cauda equina-type(n = 67), radicular-type(n = 29), and mixed-type(n = 53). Cauda equina conduction time was measured by placing disc electrodes on the abductor hallucis muscle, electrically stimulating the tibial nerve of the ankle and recording the compound muscle action potentials and F-waves. Read More

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http://dx.doi.org/10.1097/WNP.0000000000000607DOI Listing
January 2020
5 Reads

Outcome After Extreme Lateral Transpsoas Approach: Corpectomies Versus Interbody Fusion.

World Neurosurg 2019 Nov 19;131:e170-e175. Epub 2019 Jul 19.

Swedish Neuroscience Institute, Swedish Medical Center, Seattle, Washington, USA.

Introduction: The lateral transpsoas approach (LTPA) has gained popularity in thoracolumbar spine surgery procedures; however, there is an insufficient amount of data pertaining to motor and sensory complications that arise when a corpectomy is performed through the LTPA approach.

Methods: Patients who underwent a corpectomy through a LTPA at a single institution between 2006 and 2016 were analyzed. Demographics, neurological outcomes, and complications were recorded. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.07.102DOI Listing
November 2019

Cost-effectiveness of combination therapy (Mechanical Diagnosis and Treatment and Transforaminal Epidural Steroid Injections) among patients with an indication for a Lumbar Herniated Disc surgery: Protocol of a randomized controlled trial.

Physiother Res Int 2020 Jan 9;25(1):e1796. Epub 2019 Jul 9.

Department of Health Sciences, Faculty of Science, Amsterdam Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

Objectives: The general consensus is that surgical treatment is advised when conservative methods fail in patients with lumbosacral radicular syndrome (LRS). Preliminary evidence from our pilot study indicates that combination therapy (mechanical diagnosis therapy and transforaminal epidural injections) can prevent surgical treatment in patients on the waiting list for surgery. The pilot study lacked a control group, and therefore, firm conclusions pertaining to effects could not be made. Read More

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http://dx.doi.org/10.1002/pri.1796DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050498PMC
January 2020
3 Reads

Lumbar foraminal neuropathy: an update on non-surgical management.

Authors:
Young Kook Choi

Korean J Pain 2019 Jul;32(3):147-159

New Jersey Pain Medicine for the Difficult and Failed Pain, Robert Wood Johnson University Hospital Rahway, Rahway, NJ, USA.

Lumbar foraminal pathology causing entrapment of neurovascular contents and radicular symptoms are commonly associated with foraminal stenosis. Foraminal neuropathy can also be derived from inflammation of the neighboring lateral recess or extraforaminal spaces. Conservative and interventional therapies have been used for the treatment of foraminal inflammation, fibrotic adhesion, and pain. Read More

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http://dx.doi.org/10.3344/kjp.2019.32.3.147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615450PMC
July 2019
8 Reads

Ultrasound-Guided Percutaneous Peripheral Nerve Stimulation for the Treatment of Lower Extremity Pain: A Rare Case Report.

Pain Pract 2019 11 7;19(8):861-865. Epub 2019 Jul 7.

Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Jacksonville, Florida, U.S.A.

Objective: This case report presents an application of percutaneous peripheral nerve stimulation to the right superficial peroneal nerve to treat a patient with chronic intractable L5-S1 radiculopathy pain that conventional treatment failed to ameliorate.

Methods: The patient underwent an uneventful implantation of a percutaneous peripheral nerve stimulator. The implanted lead (15 cm in length and 1. Read More

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http://dx.doi.org/10.1111/papr.12810DOI Listing
November 2019
13 Reads

Sacral Myeloradiculitis: An Uncommon Complication of Genital Herpes Infection.

Pediatrics 2019 07;144(1)

Boston Children's Hospital, Boston, Massachusetts.

Herpes simplex virus 1 and 2 infections affect up to 50 million people in the United States, with a natural history of recurrent viral shedding with or without recurrence of symptoms. Although many patients remain asymptomatic or with mild symptoms, a spectrum of rare but significant nervous system complications have been reported. Although urinary retention and constipation associated with genital herpesvirus infections is often attributed to painful genital ulcerations, herpesvirus-associated lumbosacral myeloradiculitis has been reported in adults. Read More

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http://dx.doi.org/10.1542/peds.2018-2631DOI Listing
July 2019
4 Reads

Slippage reduction of lumbar spondylolisthesis using percutaneous pedicle screw with reduction fixation system after interbody fusion: A comparison with traditional open fusion and pedicle screw fixation.

J Clin Neurosci 2019 Sep 14;67:156-162. Epub 2019 Jun 14.

Department of Neurosurgery, Suwon Leon Wiltse Memorial Hospital, Suwon, Republic of Korea.

Reduction of the slipped vertebra as a part of surgical approach is still debatable. The author investigated the usefulness of percutaneous reduction fixation system for the treatment of lumbar spondylolisthesis via a comparison with traditional open pedicle screw fixation after posterior decompression and interbody fusion. This study included 65 patients with lumbar spondylolisthesis, who underwent either open transpedicular screw fixation (OTPSF) with posterior lumbar interbody fusion (PLIF) (OTPSF group, n = 33) or PPSF with reduction system (PPSFr group, n = 32) after PLIF. Read More

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http://dx.doi.org/10.1016/j.jocn.2019.05.040DOI Listing
September 2019
7 Reads

An Atraumatic Sacral Fracture with Lumbosacral Radiculopathy Complicating the Early Postpartum Period: A Case Report.

Am J Case Rep 2019 06 6;20:794-799. Epub 2019 Jun 6.

Department of General Medicine, Joondalup Health Campus, Joondalup, WA, Australia.

BACKGROUND Sacral stress fractures are rare complications of pregnancy and the early postpartum. Of these, few present with lumbosacral radiculopathy. We report the first Australian case of a young multiparous woman who sustained an atraumatic, fatigue sacral fracture with associated radiculopathy. Read More

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http://dx.doi.org/10.12659/AJCR.915764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570995PMC
June 2019
16 Reads

Correlation of the self-reported Leeds assessment of neuropathic symptoms and signs score, clinical neurological examination and MR imaging in patients with lumbo-sacral radiculopathy.

BMC Neurol 2019 May 30;19(1):107. Epub 2019 May 30.

Department of Physiotherapy, Faculty of Community and Health Sciences, University of the Western Cape, Private Bag X17, Bellville, 7535, South Africa.

Background: Lumbo-sacral radiculopathy (LSR) is a common musculoskeletal disorder for which patients seek medical care and referrals for advanced imaging. However, accurate diagnosis remains challenging. Neuropathic pain screening questionnaires, clinical neurological examination and magnetic resonance imaging (MRI) are used in the initial diagnosis. Read More

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http://dx.doi.org/10.1186/s12883-019-1333-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542141PMC
May 2019
7 Reads

Fluoroscopic evaluation of the influence of needle gauge on epidural spread in caudal block.

Medicine (Baltimore) 2019 May;98(22):e15896

Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University, School of Medicine.

Caudal block has limited injectate distribution to the desired lumbar level due to the relatively long distance from the injection site and reduction in the volume of injectate due to leakage into the sacral foramen. The objective of this study was to investigate the influence of needle gauge on fluoroscopic epidural spread and to assess the correlation between the spread level and analgesic efficacy in patients undergoing caudal block. We retrospectively analyzed data from 80 patients who received caudal block for lower back and radicular pain. Read More

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http://dx.doi.org/10.1097/MD.0000000000015896DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709147PMC
May 2019
21 Reads

Implementation of web-based hospital specialist consultations to improve quality and expediency of general practitioners' care: a feasibility study.

BMC Fam Pract 2019 05 29;20(1):73. Epub 2019 May 29.

Department of Internal Medicine, Canisius Wilhelmina Hospital, Nijmegen, the Netherlands.

Background: Rising healthcare costs due to unnecessary referrals to secondary healthcare services underscore the need for optimizing current referral procedures. This study investigates whether the use of web-based consultation (WBC) in general practice is a feasible alternative to decrease referrals.

Methods: Patients with lumbosacral radicular syndrome, knee complaints, or thyroid dysfunction, who visited the general practitioner (GP) between May 2015 and December 2016 were included for a WBC. Read More

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http://dx.doi.org/10.1186/s12875-019-0960-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540440PMC
May 2019
2 Reads

Degenerative Disc Disease: What is in a Name?

Spine (Phila Pa 1976) 2019 Nov;44(21):1523-1529

Department of General Internal Medicine, University of Washington, Seattle, WA.

Study Design: A systematic search and review OBJECTIVE.: The aim of this study was to investigate the term, degenerative disc disease, to elucidate its current usage and inform clinical, research, and policy recommendations.

Summary Of Background Data: Degenerative disc disease has long been a dominant concept in common, painful spinal disorders. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003103DOI Listing
November 2019
26 Reads

Factors Predicting Favorable Short-Term Response to Transforaminal Epidural Steroid Injections for Lumbosacral Radiculopathy.

Medicina (Kaunas) 2019 May 18;55(5). Epub 2019 May 18.

Department of Rehabilitation Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.

The purpose of this retrospective study was to identify predictors of short-term outcomes associated with a lumbosacral transforaminal epidural steroid injection (TFESI). The medical records of 218 patients, who were diagnosed with lumbosacral radiculopathy and treated with a TFESI, were reviewed in this retrospective study. A mixture of corticosteroid, lidocaine, and hyaluronidase was injected during TFESI. Read More

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http://dx.doi.org/10.3390/medicina55050162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571939PMC
May 2019
5 Reads

Lumbosacral Radiculopathy: Inciting Events and Their Association with Epidural Steroid Injection Outcomes.

Pain Med 2019 12;20(12):2360-2370

Departments of Anesthesiology and Critical Care Medicine.

Objective: Low back pain is the leading cause of worldwide disability, with lumbosacral radiculopathy accounting for over one-third of these cases. There are limited data on the relationship between etiologies and lumbosacral radiculopathy, and it is unknown whether specific causes predict treatment outcomes.

Design, Setting, And Subjects: This study explores patient-reported etiologies for lumbosacral radiculopathy in a chronic pain clinic between January 2007 and December 2015 and examines whether these causes affected epidural steroid injection outcomes. Read More

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http://dx.doi.org/10.1093/pm/pnz097DOI Listing
December 2019
7 Reads

Degenerative Lumbar Spondylolisthesis: Definition, Natural History, Conservative Management, and Surgical Treatment.

Neurosurg Clin N Am 2019 Jul;30(3):299-304

Department of Neurosurgery, Mayo Clinic Neuro-Informatics Lab, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA.

Degenerative lumbar spondylolisthesis is one of the most common causes of low back pain and is defined as displacement of one vertebra over subjacent vertebra, associated with degenerative changes, without an associated disruption or defect in the vertebral ring. Undersetanding natural history of degenerative spondylolisthesis is important to tailor an individualized management plan for each patient. A trial of conservative therapy may be considered for patients with low-grade spondylolisthesis presenting with radiculopathy and/or pseudoclaudication. Read More

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http://dx.doi.org/10.1016/j.nec.2019.02.003DOI Listing
July 2019
5 Reads