1,400 results match your criteria Lumbosacral Radiculopathy

Intraneural ganglion cyst of the lumbosacral plexus mimicking L5 radiculopathy: A case report.

World J Clin Cases 2021 Jun;9(17):4433-4440

Department of Physical Medicine and Rehabilitation, College of Medicine, Chung-Ang University, Seoul 06973, South Korea.

Background: Intraneural ganglion cysts are benign gelatinous masses that form within the epineurium of a peripheral nerve. Only few cases of intraneural ganglion cyst arising from the hip joint have been reported.

Case Summary: A previously healthy 65-year-old woman who had been experiencing left buttock pain radiating to the dorsum of the foot for 2 years visited our clinic. Read More

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Biportal endoscopic posterior lumbar decompression and vertebroplasty for extremely elderly patients affected by lower lumbar delayed vertebral collapse with lumbosacral radiculopathy.

J Orthop Surg Res 2021 Jun 14;16(1):380. Epub 2021 Jun 14.

Department of Orthopedic Surgery, Spine Center, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, 1, Singil-ro, Yeongdeungpo-gu, Seoul, Republic of Korea, 07441.

Background: Lower lumbar osteoporotic vertebral compression fracture in extremely elderly patients can often lead to lumbosacral radiculopathy (LSR) due to delayed vertebral collapse (DVC). Surgical intervention requires posterior instrumented lumbar fusion as well as vertebral augmentation or anterior column reconstruction depending on the cleft formation and intravertebral instability. However, it is necessary to decide on surgery in consideration of the patient's frail status, surgical invasiveness, and rehabilitation. Read More

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Lumbar spine teratoma with associated neuroendocrine tumour (NET) in a 37-year-old woman.

J Clin Neurosci 2021 Jul 5;89:68-70. Epub 2021 May 5.

College of Medicine & Dentistry, James Cook University, 1 James Cook Dr, Townsville, QLD, Australia.

Spinal teratoma with associated neuroendocrine tumour (NET) is a rare entity. To date there have been only three such cases reported in the literature. Information available to clinicians regarding clinical presentation, behaviour of this tumour over time, management options and follow-up, are as a consequence very limited. Read More

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Primary Intradural Extramedullary Sporadic Spinal Hemangioblastomas: CASE Report and Systematic Review.

World Neurosurg 2021 Jun 1. Epub 2021 Jun 1.

Department of Neurological Surgery, Loyola University Medical Center, Maywood, IL; Edward Hines Jr V.A. Medical Center, Hines, IL. Electronic address:

Background: Hemangioblastomas are benign vascular neoplasms of the central nervous system that may occur sporadically or in association with Von Hippel Lindau (VHL) disease. A minority of these lesions can occur in the spine, mostly as intramedullary masses. The authors present a rare CASE of primary sporadic spinal hemangioblastoma occurring as an intradural extramedullary (IDEM) lesion. Read More

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Anterior Lumbar Interbody Fusion (ALIF) L5-S1 with overpowering of posterior lumbosacral instrumentation and fusion mass: a reliable solution in revision spine surgery.

Eur Spine J 2021 Jun 3. Epub 2021 Jun 3.

IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.

Background And Purpose: In cases of spine surgical revisions of patients affected by sagittal malalignment, the restoration of the ideal lumbar lordosis (LL) is mandatory. ALIF procedures represent a powerful and effective approach to improve the LL in case of hypolordosis. This study evaluates the feasibility of ALIF to overpower posterior lumbar instrumentation and fusion mass in revision spine surgery and secondarily to estimate complications, clinical and radiological outcomes. Read More

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When infection mimics cauda equina syndrome: a cautionary tale.

Ann R Coll Surg Engl 2021 Jun;103(6):e181-e183

Queen's Hospital Burton, Burton on Trent, UK.

A 63-year-old man presented to the emergency department with low back pain, perineal and genital numbness, together with bilateral lower limb paraesthesia and urinary retention. He was admitted under the orthopaedic service for investigation of suspected cauda equina syndrome. Magnetic resonance imaging of his spine did not reveal any evidence of cauda equina compression. Read More

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Prevalence and Predictive Factors of Asymptomatic Spondylotic Cervical Spinal Stenosis in Patients with Symptomatic Lumbar Spinal Stenosis.

World Neurosurg 2021 May 24. Epub 2021 May 24.

Department of Orthopaedics, First Affiliated Hospital of Nanjing Medical University, Nanjing, China. Electronic address:

Objective: We performed a retrospective cohort study to investigate the prevalence of and risk factors for asymptomatic spondylotic cervical spinal stenosis (ASCSS) in the setting of lumbar spinal stenosis (LSS).

Methods: A total of 114 patients with a diagnosis of LSS without cervical myelopathy and radiculopathy were grouped into ASCSS and non-ASCSS groups. The medical data and radiological parameters, including age, sex, body mass index, Charlson comorbidity index, symptom duration, redundant nerve roots, dural sac cross-sectional area (DCSA), facet joint angle, lumbar lordosis angle (LLA), pelvic incidence (PI), Torg-Pavlov ratio, and lumbosacral transitional vertebrae, were analyzed. Read More

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A Case of Elsberg Syndrome in the Setting of Asymptomatic SARS-CoV-2 Infection.

J Clin Neuromuscul Dis 2021 Jun;22(4):228-231

Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY; and.

Abstract: Elsberg syndrome is a rare cause of lumbosacral radiculitis with concomitant thoracic and lumbosacral myelitis that can be seen after an acute or reactivated viral infection. After the initial coronavirus surge in New York City, a 68-year-old man developed progressive lower extremity weakness and a defined sensory level at the lower abdomen. He had highly elevated SARS-CoV-2 IgG antibodies despite an absence of preceding COVID-19 symptoms. Read More

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Identifying treatment patterns in patients with Bertolotti syndrome: an elusive cause of chronic low back pain.

Spine J 2021 May 16. Epub 2021 May 16.

Center for Spine Health, Department of Neurosurgery, Neurologic Institute, Cleveland Clinic Foundation, 9500 Euclid Av, Suite S40, Cleveland, OH, 44195, USA; Department of Neurosurgery, Cleveland Clinic Lerner College of Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA.

Background Context: Bertolotti Syndrome is a diagnosis given to patients with lower back pain arising from a lumbosacral transitional vertebra (LSTV). These patients can experience symptomatology similar to common degenerative diseases of the spine, making Bertolotti Syndrome difficult to diagnose with clinical presentation alone. Castellvi classified the LSTV seen in this condition and specifically in types IIa and IIb, a "pseudoarticulation" is present between the fifth lumbar transverse process and the sacral ala, resulting in a semi-mobile joint with cartilaginous surfaces. Read More

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Repeat Epidural Injections of SP-102 (Dexamethasone Sodium Phosphate Injectable Gel) in Subjects with Lumbosacral Radiculopathy.

J Pain Res 2021 5;14:1231-1239. Epub 2021 May 5.

Global Research and Development, Scilex Pharmaceuticals Inc, Palo Alto, CA, USA.

Purpose: SP-102 is a novel epidural steroid injection (ESI) formulation of 10 mg dexamethasone sodium phosphate in a viscous gel solution. Repeat dosing of ESIs is possible if required for pain relief, but with consideration of hypothalamic-pituitary-adrenal (HPA) axis suppression from prolonged systemic exposure. This phase I/II study investigated the effect of initial and repeat SP-102 injections on HPA suppression and analgesia. Read More

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Reliability and validity of the Istanbul low back pain disability index in lumbosacral radiculopathy.

J Back Musculoskelet Rehabil 2021 Apr 30. Epub 2021 Apr 30.

Department of Physical Medicine and Rehabilitation, Marmara University Faculty of Medicine, Division of Rheumatology, Istanbul, Turkey.

Background: Lumbosacral radiculopathy is associated with a broad range of complaints; therefore, specific disability measurements should be validated for this condition.

Objectives: The aim of this study was to investigate the validity and reliability of the Istanbul Low Back Pain Disability Index (ILBPDI) in lumbosacral radiculopathy.

Methods: Patients diagnosed with radiculopathy caused by a disc herniation were included. Read More

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Association of Lumbar Paraspinal Muscle Morphometry with Degenerative Spondylolisthesis.

Int J Environ Res Public Health 2021 04 12;18(8). Epub 2021 Apr 12.

Department of Physical Medicine & Rehabilitation, College of Medicine, Kyung Hee University, Seoul 02447, Korea.

The objective of this study was to assess the cross-sectional areas (CSA) of lumbar paraspinal muscles and their fatty degeneration in adults with degenerative lumbar spondylolisthesis (DLS) diagnosed with chronic radiculopathy, compare them with those of the same age- and sex-related groups with radiculopathy, and evaluate their correlations and the changes observed on magnetic resonance imaging (MRI). This retrospective study included 62 female patients aged 65-85 years, who were diagnosed with lumbar polyradiculopathy. The patients were divided into two groups: 30 patients with spondylolisthesis and 32 patients without spondylolisthesis. Read More

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Traumatic Bilateral L3-4 Facet Dislocation With Open Decompression and Short Segment Fusion.

Int J Spine Surg 2021 Feb 18;14(s4):S21-S25. Epub 2021 Jan 18.

Department of Orthopaedics & Rehabilitation, University of Rochester Medical Center, Rochester, New York.

Traumatic lumbar facet dislocations are exceedingly rare, with reported cases primarily involving the lumbosacral junction. This injury arises from very high flexion distraction forces imparted on the lumbar spine. Herein we describe a bilateral L3-4 facet dislocation, a particularly rare injury pattern, using a short-segment posterior decompression and fusion followed by an interbody fusion through a lateral approach. Read More

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February 2021

Cauda equina syndrome due to herpes simplex virus type 2-associated meningoradiculitis (Elsberg syndrome) after posterior lumbar spinal fusion surgery: Case report and review of literature.

Clin Neurol Neurosurg 2021 Apr 1;205:106624. Epub 2021 Apr 1.

Functional Neurosurgery Research Center, Shohada Tajrish Comprehensive Neurosurgical Center of Excellence, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address:

Elsberg syndrome is a rare but well-defined clinical condition, including acute or subacute lumbosacral meningoradiculitis, which might be accompanied by myelitis and is often associated with herpes simplex virus type 2 (HSV-2) infection. We report the case of an immunocompetent 24-year-old man who presented with perineal pain, saddle hypoesthesia, and urinary retention associated with Elsberg syndrome due to HSV-2 infection 20-day after the posterior lumbar spinal fusion surgery. Lumbar magnetic resonance imaging (MRI) with gadolinium enhancement showed mildly enhanced and swollen right sacral nerve roots. Read More

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Postpartum lumbosacral radiculopathy: a neuraxial anaesthesia complication or an intrinsic obstetric palsy?

BMJ Case Rep 2021 Apr 21;14(4). Epub 2021 Apr 21.

Anesthesiology, Centro Hospitalar Universitário Lisboa Norte EPE, Lisbon, Portugal.

Postpartum peripheral nerve disorders are an uncommon obstetrical complication, with most cases resulting from intrinsic obstetric palsies. We present the case of a full-term nulliparous pregnant 33-year-old woman with a vacuum-assisted vaginal delivery due to a prolonged second stage of labour and occipitoposterior position of the fetal head. For analgesia, a combined spinal-epidural technique was used. Read More

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Population Pharmacokinetics of Vixotrigine in Healthy Volunteers and Subjects with Trigeminal Neuralgia, Painful Lumbosacral Radiculopathy and Erythromelalgia.

Eur J Drug Metab Pharmacokinet 2021 May;46(3):395-404

Ann Arbor Pharmacometrics Group, Ann Arbor, MI, USA.

Background: Vixotrigine is a voltage and use dependent sodium channel blocker currently under development for treatment of various neuropathic pain indications.

Objective: The objective of this work was to develop a population pharmacokinetic model and assess effects of various covariates on pharmacokinetic parameters of vixotrigine.

Method: Plasma concentration-time data from 12 Phase 1 or 2 studies were included in the analyses. Read More

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Lumbosacral Radiculoplexus Neuropathy: Neurologic Outcomes and Survival in a Population-Based Study.

Neurology 2021 04 2;96(16):e2098-e2108. Epub 2021 Mar 2.

From the Departments of Neurology (M.V.P., R.S.L., P.J.D., P.J.B.D.), Radiology (B.M.H.), and Biomedical Statistics and Informatics (P.T.), Mayo Clinic, Rochester, MN; and Department of Neurology, National Neuroscience Institute (P.-S.N.), Singapore.

Objective: To determine whether patients in the community with lumbosacral radiculoplexus neuropathy (LRPN) have milder neuropathy than referral patients, we characterized the outcomes and survival of population-based compared to referral-based LRPN cohorts.

Background: Previously, we found that the incidence of LRPN is 4.16/100,000/y, a frequency greater than other inflammatory neuropathies. Read More

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Comparison Between a Single Subpedicular Transforaminal Epidural Steroid Injection and Lateral Recess Steroid Injection in Reducing Paracentral Disc Herniation-Related Chronic Neuropathic Leg Pain: A Retrospective Study.

World Neurosurg 2021 May 9;149:e392-e399. Epub 2021 Feb 9.

Department of Anesthesiology, All India Institute of Medical Sciences, Bhopal, India.

Background: This retrospective study compares the results of 2 different techniques of transforaminal epidural steroid injection (TFESI)-subpedicular (SP-TFESI) and lateral recess epidural steroid injection (LRSI) in relieving chronic lumbar radicular pain.

Methods: Records of 97 patients who had undergone injection for unilateral lumbar radicular pain and had a paracentral disc were analyzed. Numerical rating scale (NRS) and Oswestry Disability Index (ODI) scores were measured at baseline and at 2, 4, 12, and 24 weeks thereafter. Read More

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Qualitative Sensory Testing in Outcome Prediction of Transforaminal Epidural Steroid Injection for Chronic Painful Unilateral Lumbosacral Radiculopathy: Prospective Observational Study.

Pain Pract 2021 Jan 27. Epub 2021 Jan 27.

Clinic of Anaesthesiology and Intensive Care, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

Background: Transforaminal epidural steroid injection (TFESI) is widely practiced for the treatment of radicular pain. As its effectiveness is still subject to debate, a better patient selection for TFESI is necessary. We aimed to evaluate the potential of bedside-suitable qualitative sensory testing (QualST) to determine the early effectiveness of TFESI for the treatment of chronic lumbosacral radiculopathy (LSR)-related pain. Read More

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January 2021

Retrospective radiographic analysis of anterior lumbar fusion for high grade lumbar spondylolisthesis.

J Spine Surg 2020 Dec;6(4):650-658

Mayo Clinic Arizona, 5777 E Mayo Blvd, Phoenix, AZ, USA.

Background: High-grade spondylolisthesis (>50% slippage) is infrequently encountered in adults and frequently requires surgical treatment. The optimal surgical treatment is controversial with limited literature guidance as to optimal approach to treatment. An observational study to examine the technique and radiographic outcomes of adult patients treated with anterior lumbar interbody fusion (ALIF) and posterior percutaneous instrumentation for high-grade spondylolisthesis. Read More

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December 2020

Repetitive Peripheral Magnetic Stimulation (rPMS) in Subjects With Lumbar Radiculopathy: An Electromyography-guided Prospective, Randomized Study.

In Vivo 2021 Jan-Feb;35(1):623-627

Department of Physical and Rehabilitation Medicine, "Elias" Emergency University Hospital, Bucharest, Romania.

Background/aim: Lumbar radiculopathy refers to the disruption of one or more lumbosacral nerve root functions, usually causing radiating pain and functional impairments.

Patients And Methods: We aimed to analyze the role of repetitive peripheral magnetic stimulation (rPMS) alone or in association with physiokinesiotherapy (PKT) in treating lumbar radiculopathy. A total of 41 patients diagnosed with lumbar radiculopathy were randomly allocated to the rPMS group and the rPMS plus PKT group. Read More

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Quantitative Evaluation of Intraspinal Lumbar Disc Herniation-related Lumbosacral Radiculopathy Before and After Percutaneous Transforaminal Endoscopic Discectomy Using Diffusion Tensor Imaging.

Spine (Phila Pa 1976) 2021 Jul;46(13):E734-E742

The Department of Orthopedics, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Study Design: A prospective study.

Objective: The aim of this study was to investigate the relationship between diffusion tensor imaging (DTI) derived parameters of compressed nerve roots at subregions and the corresponding clinical symptoms to evaluate the patients with intraspinal lumbar disc herniation (LDH)-related lumbosacral radiculopathy pre- and postoperatively.

Summary Of Background Data: It is crucial to explore whether magnetic resonanve imaging (MRI) can quantitatively evaluate intraspinal LDH-related lumbosacral radiculopathy before and after surgery. Read More

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Postfixed lumbosacral plexus with split L5 ventral ramus and furcal nerve arising from L5.

Morphologie 2020 Dec 1. Epub 2020 Dec 1.

Department of Anatomical Sciences, St. George's University, St. George's, Grenada, West Indies; Department of Neurosurgery, Tulane Center for Clinical Neurosciences, Tulane University School of Medicine, New Orleans, LA, USA; Department of Neurology, Tulane University School of Medicine, New Orleans, LA, USA; Department of Structural & Cellular Biology, Tulane University School of Medicine, New Orleans, LA, USA; Department of Neurosurgery and Ochsner Neuroscience Institute, Ochsner Health System, New Orleans, LA, USA.

Variations of the peripheral nerve plexuses are important to those clinicians who diagnose and treat patients with pathology of their parts. During routine dissection, a postfixed lumbosacral plexus with a furcal nerve arising from L5, not L4, was discovered. In addition, the case was found to have a split L5 ventral ramus. Read More

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December 2020

Clinical outcome of biportal endoscopic revisional lumbar discectomy for recurrent lumbar disc herniation.

J Orthop Surg Res 2020 Nov 23;15(1):557. Epub 2020 Nov 23.

Department of Orthopedic Surgery, Spine Center, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, 1, Singil-ro, Yeongdeungpo-gu, Seoul, Republic of Korea.

Background: Although literature provides evidence regarding the superiority of surgery over conservative treatment in patients with lumbar disc herniation, recurrent lumbar disc herniation (RLDH) was the indication for reoperation in 62% of the cases. The major problem with revisional lumbar discectomy (RLD) is that the epidural scar tissue is not clearly isolated from the boundaries of the dura matter and nerve roots; therefore, unintended durotomy and nerve root injury may occur. The biportal endoscopic (BE) technique is a newly emerging minimally invasive spine surgical modality. Read More

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November 2020

Retrospective Assessment of Salvage to 10 kHz Spinal Cord Stimulation (SCS) in Patients Who Failed Traditional SCS Therapy: RESCUE Study.

J Pain Res 2020 10;13:2861-2867. Epub 2020 Nov 10.

Carolinas Pain Institute, Winston-Salem, NC 27103, USA.

Background And Objectives: A randomized clinical trial demonstrated that 10 kHz SCS (10kHz-SCS) therapy is superior to traditional low-frequency SCS (LF-SCS) at 12- and 24-month clinical follow-ups and led to Food and Drug Administration (FDA) approval of the therapy. The results of the study led our practices to trial 10kHz-SCS in patients who had not maintained pain relief with LF-SCS therapy. Here, we report a large set of data from two clinical sites to assess if 10kHz-SCS is an effective salvage modality when LF-SCS fails. Read More

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November 2020

Lumbosacral extradural extramedullary hematopoiesis in thalassemia major causing spinal canal stenosis.

Surg Neurol Int 2020 8;11:331. Epub 2020 Oct 8.

Department of Neurosurgery, Rutgers Robert Wood Johnson University Hospital, New Brunswick, New Jersey, United States.

Background: Extramedullary hematopoiesis (EH) is common in patients with ineffective erythropoiesis like thalassemia major (TM). EH commonly involves intra-abdominal organs (e.g. Read More

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October 2020

Rapid Growth of a Facet Joint Cyst Mimicking an Aggressive Tumor in the Lumbar Spine.

J Neurosci Rural Pract 2020 Oct 31;11(4):646-650. Epub 2020 Aug 31.

Department of Neurosurgery, Leeds General Infirmary, Leeds, United Kingdom.

A 67-year-old patient with a history of fully treated bowel carcinoma presented with a short history of unilateral lumbosacral radiculopathy. No neurological deficit was found on examination. Magnetic resonance imaging (MRI) demonstrated initially L4/5 foraminal narrowing that was believed to be the cause for the patient's symptoms; however, a nerve root block led to no improvement in symptoms. Read More

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October 2020

Are epidural corticosteroid injections effective for lumbosacral radicular pain? A Cochrane Review summary with commentary.

NeuroRehabilitation 2020 ;47(4):509-511

IRCCS Istituto Ortopedico Galeazzi, Italy.

Background: Epidural corticosteroid injection is one of the most common non-surgical procedures for lumbosacral radicular pain.

Objective: To assess efficacy and safety of epidural corticosteroid injections compared with placebo injections in patients with lumbosacral radicular pain.

Methods: A summary and commentary of a Cochrane Review by Oliveira et al. Read More

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Comparison between anteroposterior and oblique "Scotty dog" approach during S1 transforaminal epidural steroid injection: A randomized controlled trial.

Medicine (Baltimore) 2020 Oct;99(43):e22895

Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

Background: Traditionally, S1 transforaminal epidural steroid injection (TFESI) has been performed using an anteroposterior (AP) fluoroscopic view. In 2007, the oblique "Scotty dog" (OS) approach was introduced as an alternative technique. We compared passage time of the needle into S1 foramen (Tf) between the anteroposterior (AP) and oblique "Scotty dog" (OS) approach during S1 TFESI. Read More

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October 2020