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Spine (Phila Pa 1976) 2022 Jun 7;47(12):849-858. Epub 2022 Mar 7.

Department of Neurosurgery, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany.

Study Design: We performed a prospective nonblinded single center observational study.

Objective: To investigate the relationship between expectations, outcome, and satisfaction with the outcome in patients undergoing cervical spine stabilization surgery.

Summary Of Background Data: In modern healthcare, patient-reported outcome measures and patient satisfaction have become an important aspect of quality control. Read More

Cureus 2022 May 22;14(5):e25212. Epub 2022 May 22.

Neurosurgery, Inova Neuroscience Institute, Falls Church, USA.

Spinal epidural lipomatosis (SEL) is a common pathology of the lumbar spine. While the natural history is not well understood, there is a strong association with metabolic syndrome and endocrine dysfunction. Clinical presentation typically involves slow, progressive onset of radicular and myelopathic symptoms. Read More

Biomedicines 2022 Jun 4;10(6). Epub 2022 Jun 4.

Neuropathological Institute, University Hospitals Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany.

The treatment options for neuropathic pain caused by lumbar disc herniation have been debated controversially in the literature. Whether surgical or conservative therapy makes more sense in individual cases can hardly be answered. We have investigated whether a machine learning-based prediction of outcome, regarding neuropathic pain development, after lumbar disc herniation treatment is possible. Read More

Front Endocrinol (Lausanne) 2022 6;13:901265. Epub 2022 Jun 6.

Department of Trauma and Orthopaedic Surgery, Division of Orthopaedics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Intact mineralization of the auditory ossicles - the smallest bones in the body - is essential for sound transmission in the middle ear, while ossicular hypomineralization is associated with conductive hearing loss. Here, we performed a high-resolution analysis of the ossicles in vitamin D receptor deficient mice ( ), which are characterized by hypocalcemia and skeletal mineralization defects, and investigated whether local hypomineralization can be prevented by feeding a calcium-rich rescue diet ( ). In mice fed a regular diet ( ), quantitative backscattered electron imaging (qBEI) revealed an increased void volume (porosity, p<0. Read More

Rev Bras Med Trab 2021 Oct-Dec;19(4):465-471. Epub 2021 Dec 30.

Departamento de Educação Integrada em Saúde, Universidade Federal do Espírito Santo, Vitória, Espírito Santo, Brazil.

Introduction: Musculoskeletal symptoms can affect workers' quality of life and work productivity, leading to sick leave and company losses.

Objectives: To identify the prevalence of musculoskeletal symptoms among administrative workers at a hospital in the state of Espírito Santo, the most frequent complaints, and the associated personal and occupational factors.

Methods: This is an observational, cross-sectional study. Read More

World Neurosurg 2022 Jun 17. Epub 2022 Jun 17.

Department of Neurological Surgery, Case Western Reserve University School of Medicine, MetroHealth Medical Center, Cleveland, OH, United States of America. (2500 MetroHealth Drive Cleveland, Ohio 44109). Electronic address:

Background: Most vertebral compression fractures (VCFs) are successfully managed conservatively, however, some patients fail conservative management and require further surgical treatment. Here, we identify significant variables that contribute to progressive vertebral collapse in non-operative treatment of traumatic VCFs.

Methods: A systematic review using PRISMA guidelines identified original research articles of conservatively managed VCF secondary to trauma from inception to September 2021. Read More

Cureus 2022 May 17;14(5):e25086. Epub 2022 May 17.

Neurological Surgery, American Neurospine Institute, Plano, USA.

Sarcopenia is a muscle-wasting disease common among older adults. The condition has been associated with adverse perioperative and postoperative outcomes following spinal surgery. The combination of this muscle-wasting syndrome and spondylolisthesis and how we approached the case makes it a compelling study for surgeons attempting to treat this patient population more effectively. Read More

World Neurosurg 2022 Jun 15. Epub 2022 Jun 15.

Investigations performed at Pediatric Orthopaedics; Department of Trauma, Orthopaedic and Plastic Surgery, University Medical Center Goettingen; Robert-Koch-Str. 40, 37075, Goettingen, Germany.

Background: The majority of children with spinal muscular atrophy (SMA) develop spinal deformity, which may require surgical intervention. In addition to poor bone stock, vertebral body shape may hinder the placement of spinal implants resulting in complications and poor outcome. The aim of this study was to analyze whether vertebral body morphology of SMA children and adolescents is altered in comparison to healthy age-matched controls. Read More

Sci Rep 2022 Jun 17;12(1):10189. Epub 2022 Jun 17.

Department of Preventive Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.

There is a clear relationship between rheumatoid arthritis (RA) and major osteoporotic fracture (MOF), although there is limited evidence on the effect of continuity of care (COC) on MOF in these patients. We investigated the association between COC and risk of MOF, including fractures of the lumbar spine and pelvis, forearm, and hip, among newly diagnosed RA patients aged ≥ 60 years. A total of 8715 incident RA patients from 2004 to 2010 were included from the Korean National Health Insurance Service-Senior cohort database. Read More

Eur J Radiol 2022 Jun 1;154:110343. Epub 2022 Jun 1.

Radiology Unit, "Casa Sollievo della Sofferenza" Hospital, San Giovanni Rotondo, Italy; Radiology Unit "Dimiccoli" Teaching Hospital, Barletta, Italy; Department of Clinical and Experimental Medicine, Foggia University School of Medicine, Italy. Electronic address:

Spine trauma is an ominous event with a high morbidity, frequent mortality, and significant psychological, social, and financial consequences for patients, their relatives and society. On average three out of four spinal fractures involve the thoracolumbar spine and up to one-third are complicated by spinal cord injury. Spinal cord injuries (SCI) are a significant cause of disability in US and in all western countries. Read More

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2022 Jun;36(6):653-659

Department of Spine Surgery, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou Guangdong, 510630, P. R. China.

Objective: To review and evaluate the technical advantages and disadvantages and research progress of percutaneous endoscopic lumbar interbody fusion.

Methods: The domestic and foreign related research literature on percutaneous endoscopic lumbar interbody fusion was extensively consulted. The advantages, disadvantages, and effectiveness were summarized. Read More

Orthop Surg 2022 Jun 16. Epub 2022 Jun 16.

University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Orthopedics and Trauma Surgery, Cologne, Germany.

Objective: To assess which radiological alignment parameters are associated with a satisfactory long-term clinical outcome after performing lumbar spinal fusion for treating degenerative spondylolisthesis.

Methods: This single-center prospective study assessed the relation between radiological alignment parameters measured on standing lateral lumbar spine radiographs and the patient-reported outcome using four different questionnaires (COMI, EQ-5D, ODI and VAS) as primary outcome measures (level of evidence: II). The following spinopelvic alignment parameters were used: gliding angle, sacral inclination, anterior displacement, sagittal rotation, lumbar lordosis, sacral slope, pelvic tilt and pelvic incidence. Read More

World J Surg Oncol 2022 Jun 16;20(1):208. Epub 2022 Jun 16.

Department of Orthopedics, Trauma and Plastic Surgery, University Hospital Leipzig, Liebigstraße 20, 04103, Leipzig, Germany.

Background: No comparison of a single hypervascular tumor entity in terms of major complications in different spinal regions has been performed. We aimed to evaluate post-embolic and post-operative outcomes in anatomic regions with renal cell carcinoma (RCC) metastases to the spine.

Methods: We retrospectively evaluated data from patients with confirmed, embolized, and surgically treated RCC spine metastases at a single-spine center between 2010 and 2020. Read More

Traffic Inj Prev 2022 Jun 16:1-6. Epub 2022 Jun 16.

Department of Emergency Medicine, Alpert Medical School of Brown University and Hasbro Children's Hospital, Providence, Rhode Island.

Objective: The objective was to develop a disability-based metric for quantifying disability rates as a result of motor vehicle crash (MVC) spine injuries and compare functional outcomes between pediatric and adult subgroups.

Methods: Disability rate was quantified using Functional Independence Measure (FIM) scores within the National Trauma Data Bank-Research Data System for the top 95% most frequent Abbreviated Injury Scale (AIS) 3 spine injuries (14 unique injuries). Pediatric (7-18 years), young adult (19-45 years), middle-aged adult (46-65 years), and older adult (66+ years) MVC occupants with FIM scores available and at least one of the 14 spine injuries were included. Read More

Am J Case Rep 2022 Jun 16;23:e936179. Epub 2022 Jun 16.

Department of Orthopaedic and Spine Surgery, Evangelismos Hospital, Paphos, Cyprus.

BACKGROUND Pyogenic spondylitis comprises several clinical entities, including native vertebral osteomyelitis, septic discitis, pyogenic spondylodiscitis, and epidural abscess. The lumbar spine is most often infected, followed by the thoracic and cervical areas. It mainly develops (i) after spine surgery; (ii) from history of blunt trauma to the spinal column; (iii) from infections in adjacent structures (such as soft tissues); (iv) from iatrogenic inoculation after invasive procedures (such as lumbar puncture); and (v) from hematogenous bacterial spread to the vertebra (mainly through the venous route). Read More

Physiother Theory Pract 2022 Jan 4:1-9. Epub 2022 Jan 4.

Department of Neurosciences, Rehabilitation, Ophthalmology, Genetic and Maternal Infantile Sciences (Dinogmi), University of Genova - Campus of Savona, Savona, Italy.

Background: The prevalence of Thoracic Pain (TP) is estimated to be low compared to other common musculoskeletal disorders such as nonspecific low back pain (LBP). Notably, compared to LBP, TP or referral pain to the thoracic area potentially may involve serious pathologies. Visceral referral of pain may present to the thoracic spine or anteriorly in the abdomen or chest. Read More

Acta Orthop Traumatol Turc 2022 May;56(3):210-216

Department for Orthopedics, Trauma and Plastic Surgery, University Hospital Leipzig, Leipzig, Germany.

Objective: The aim of the study was to assess the relationship between the expression of elastin, collagen type I, II,III and the degenera- tion of the facet joint capsule and the ligamentum flavum.

Methods: 10 patients (4 male, 6 female) (mean age 61 ± 14,9) undergoing surgery for degenerative lumbar spine syndrome and 5 cadav- ers (3 male, 2 female) (age of death 87 ± 8,6 years) were included in this study. One set of tissue samples was taken from each patient in the patient group intraoperatively and two sets of samples were taken from each cadaver in the cadaver group posthumosly from the ligamentum flavum (medial and lateral) and from the facet joint capsules (superior and inferior articular process) at the L4/5 segment. Read More

BMC Musculoskelet Disord 2022 Jun 14;23(1):575. Epub 2022 Jun 14.

Department of Radiology, The Third Hospital of Hebei Medical University, No. 139 Ziqiang St, Qiaoxi District, Shijiazhuang, Hebei, CN 050050, China.

Background: To explore the vertebral deformity angle (VD angle) of 1 lumbar vertebral body (L1) in elderly women, investigate the influence of VD on vertebral stiffness (VS) by biomechanical analysis using quantitative computed tomography-based finite element analysis (QCT-FEA).

Methods: Two hundred seventy eight participants were recruited, and underwent QCT scan. Measured VD angles of L1, and constructed QCT-FEA models of L1 with the minimum (0. Read More

Chin J Traumatol 2022 May 18. Epub 2022 May 18.

School of Rehabilitation, Capital Medical University, Beijing, 100068, China; Department of Spine and Spinal Cord Surgery, Beijing Boai Hospital, China Rehabilitation Research Center, Beijing, 100068, China. Electronic address:

Purpose: The long-term situation of children with spinal cord injury (SCI) was investigated, and suggestions for helping them better return to the society were provided.

Methods: SCI patients less than 18 years old hospitalized in Beijing Boai Hospital from January 2011 to December 2020 were retrospectively analyzed. Information including motor function, complications, characteristic changes, self-care abilities, school attendance and social participation were collected by telephone interview and electronic questionnaire. Read More

Arch Osteoporos 2022 Jun 9;17(1):83. Epub 2022 Jun 9.

Interdisciplinary Center of Bone Diseases, Bone and Joint Department, Lausanne University Hospital, Lausanne, Switzerland.

Lumbar spine bone mineral density (BMD) and trabecular bone score (TBS) are both calculated on L1-L4 vertebrae. This study investigated the ability to predict osteoporotic fractures of BMD and TBS as calculated based on all possible adjacent L1-L4 vertebrae combinations. Present findings indicate that L1-L3 is an optimal combination to calculate LS-BMD or TBS. Read More

World Neurosurg 2022 Jun 4. Epub 2022 Jun 4.

Department of Surgery, Yorkshire and Humber Deanery. Electronic address:

Study Design: Systematic review OBJECTIVE: The objective of this systematic review is to determine the fate of spinal implants when the patients develop postoperative wound infection after posterior instrumental fusion in a degenerative spine.

Methods: A systematic review of the English-language literature (published between January 2001 and July 2020) was undertaken to identify articles documenting the management strategy for surgical-site infections after posterior lumbar spinal fusion. Studies on pedicle screw fixation after trauma, immunocompromised, metastatic spine disease, and combined anterior/posterior approach were excluded. Read More

Front Endocrinol (Lausanne) 2022 20;13:882163. Epub 2022 May 20.

Department of Diagnostic and Interventional Neuroradiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.

Purpose: To establish and evaluate the diagnostic accuracy of volumetric bone mineral density (vBMD) threshold values at different spinal levels, derived from opportunistic quantitative computed tomography (QCT), for the prediction of incident vertebral fractures (VF).

Materials And Methods: In this case-control study, 35 incident VF cases (23 women, 12 men; mean age: 67 years) and 70 sex- and age-matched controls were included, based on routine multi detector CT (MDCT) scans of the thoracolumbar spine. Trabecular vBMD was measured from routine baseline CT scans of the thoracolumbar spine using an automated pipeline including vertebral segmentation, asynchronous calibration for HU-to-vBMD conversion, and correction of intravenous contrast medium (https://anduin. Read More

Zhonghua Fu Chan Ke Za Zhi 2022 May;57(5):346-351

Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing 100034, China.

To verify the efficacy and safety of daily oral minodronate in postmenopausal women with established osteoporosis. In this randomized, double-blinded, placebo-controlled trial, 262 postmenopausal women were enrolled. Patients were randomized to receive daily oral minodronate 1 mg with supplements of 500 mg calcium and 200 U vitamin D (=130) or placebo (=132) with daily supplements of 500 mg calcium and 200 U vitamin D, for 48 weeks. Read More

Biomed Res Int 2022 25;2022:2863379. Epub 2022 Apr 25.

Department of Spinal Surgery, The Third Affiliated Hospital of Shihezi University Medical College, Shihezi, 832000 Xinjiang Uygur Autonomous Region, China.

This research was developed to accurately evaluate the unstable fractures of thoracolumbar before and after surgery and discuss the treatment timing and methods. Three-dimensional (3D) finite element method was adopted to construct the T-L segment model of human body. The efficiency of percutaneous kyphoplasty (PKP) and percutaneous vertebroplasty (PVP), two commonly used internal fixation procedures, was retrospectively compared. Read More

BMC Surg 2022 Jun 2;22(1):212. Epub 2022 Jun 2.

Department of Spine, General Hospital of Pingmei Shenma Medical Group, Pingdingshan City, Henan Province, China.

Background: A ruptured drainage tube which remains in the incision is a rare surgical complication. The usual mode of retrieval is to detach the suture and explore the pre-existing incisional wound. However, spinal endoscopy provides an alternative method for successful removal, avoiding the enlargement of the surgical wound. Read More

Semin Musculoskelet Radiol 2022 Jun 2;26(3):314-328. Epub 2022 Jun 2.

Department of Musculoskeletal Radiology, Hôpital Cochin, AP-HP Centre, Université de Paris, Paris, France.

Management of patients after lumbar spine surgery or interventional radiology can be complex, and postoperative imaging patterns are often poorly understood by nonspecialized radiologists. This article focuses on postoperative imaging features of the lumbar spine in five clinical settings (with corresponding interventions): vertebral osteoporotic fractures (percutaneous vertebroplasty and vertebral augmentation), lumbar disk herniation (surgical diskectomy and percutaneous interventional radiology), lumbar spinal stenosis (surgical decompression), lumbar spondylolisthesis (surgical decompression and fusion), and degenerative scoliosis (techniques of osteotomies).For each intervention, we discuss imaging indications, depending if the patient is asymptomatic or if there are suspected complications, describe normal and pathologic imaging features, and present key points. Read More

Ulus Travma Acil Cerrahi Derg 2022 Jun;28(6):857-862

Department of Neurosurgery, İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, İstanbul-Turkey.

Background: The aim of the study was to investigate the relationship between the interpedicular distance increase ratio and the ratio of canal compromise in thoracolumbar burst fractures.

Methods: Thirty-one patients (18 male and 13 female) with an average age of 30.8 (14-57) who had been treated for thoraco-lumbar burst fractures in the Department of Orthopaedics and Traumatology were included in the study. Read More

Emerg Med Int 2022 20;2022:2577920. Epub 2022 May 20.

The Second Department of Spine, Baoji Hospital of Traditional Chinese Medicine, Baoji, Shanxi 721001, China.

Background: Lumbar spondylolisthesis is a common clinical spinal lesion. The upper vertebral body of the patient is displaced relative to the lower vertebral body, causing spinal instability and nerve compression. The clinical manifestations are low back and leg pain, abnormal lower limb sensation, and intermittent rupture. Read More

J Therm Biol 2022 May 15;106:103247. Epub 2022 Apr 15.

Department of Animal Medicine, Production and Health, University of Padova, 35020, Legnaro, Italy. Electronic address:

The aim this study was to evaluate variation in body surface temperature (BST) in healthy and spinal cord injured (SCI) dogs, and to outline temperature variation at rest (T0), during (T1) and after (T2) water-treadmill physiotherapy sessions in SCI using infrared thermography (IRT). Sixty-seven dogs of different sex, breed, body weight and age were enrolled: 14 healthy dogs and 53 dogs affected by disc pathologies. The study examined three regions of interest (ROIs): the total image of the spine (IMAGE), the spinal cord area from 1st thoracic vertebra to the last lumbar vertebra (AR01) and the surgery wound or spinal cord lesion area (AR02). Read More

J Sports Sci 2022 May 28:1-7. Epub 2022 May 28.

School of Sport Exercise and Health Sciences, Loughborough University, Loughborough, UK.

Cricket fast bowling is associated with a high prevalence of lumbar bone stress injuries (LBSI), especially in adolescent bowlers. This has not been sufficiently explained by risk factors identified in adult players. This study aimed to examine the incidence of LBSI in adolescent fast bowlers over a prospective study and potential risk factors. Read More