Search Our Scientific Publications & Authors

Comput Methods Programs Biomed 2020 Jun 20;196:105618. Epub 2020 Jun 20.

RBG Labs, Department of Engineering Design, IIT Madras, Chennai 600036, India. Electronic address:

Background And Objective: Recent research and tested data suggested that spinal injuries occur more often in a frontal impact. Most of the published information is focused on the lumbar spinal injury with respect to axial compression force by varying the height of drops. Parametric studies on the lumbar spinal injury are very scanty. Read More

Medicine (Baltimore) 2020 Jun;99(25):e20524

Department of Minimally Invasive Spine Surgery, the Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, No.109, Xueyuan Western Road, Wenzhou City, Zhejiang Province, P.R. China.

Background: It is currently controversial whether unilateral or bilateral balloon kyphoplasty (BKP) is superior in terms of postoperative outcomes in treatment of osteoporotic vertebral compression fracture (OVCF). In this context, the aim of this study was to prospectively evaluate and compare the radiographic and clinical outcomes of BKP using unilateral and bilateral approaches.

Methods: This was a randomized controlled study and was approved by the Severance Institutional Review Board in our hospital. Read More

Case Rep Crit Care 2020 4;2020:2425973. Epub 2020 Jun 4.

Advent Health, Orlando, FL, USA.

Objective: This case describes symptomatic pulmonary cement embolism as a rare postvertebroplasty complication and highlights its critical yet ill-defined management.

Background: Pulmonary cement embolism (PCE) is a feared complication of vertebroplasty in the treatment of vertebral fractures. While the majority of PCEs are asymptomatic, symptomatic PCEs often present with chest pain, tachycardia, signs of severe respiratory distress, and death. Read More

World Neurosurg 2020 Jun 10. Epub 2020 Jun 10.

Mayo Clinic Neuro-Informatics Laboratory, Department of Neurologic Surgery, Mayo Clinic, Rochester, MN, USA; Department of Neurologic Surgery, Mayo Clinic, Rochester, MN, USA. Electronic address:

Introduction: Vertebral cement augmentation techniques are routinely employed to treat osteoporotic vertebral compression fractures (VCF). In the current study, we employed a state-level outpatient database to compare costs and post-operative outcomes between vertebroplasty and kyphoplasty.

Methods: We queried the 2016 Florida State-Ambulatory Surgery Database of the Healthcare Cost and Utilization Project for patients undergoing thoraco-lumbar vertebroplasty or kyphoplasty for osteoporotic VCFs. Read More

Asian Spine J 2020 Jun 12. Epub 2020 Jun 12.

Department of Orthopedic Surgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

Study Design: A single-center retrospective study.

Purpose: To investigate the prevalence of proximal junctional kyphosis (PJK) and its risk factors after surgical treatment of adult spinal deformity (ASD) with oblique lateral interbody fusion (OLIF).

Overview Of Literature: Correction of ASD using OLIF has been developed because it is less invasive, and enables correction of severe deformities. Read More

Clin Nucl Med 2020 Aug;45(8):659-660

From the Department of Nuclear Medicine, University at Buffalo.

A 73-year-old man with chronic obstructive pulmonary disease and no known malignancies was evaluated for back pain. MR examination showed lumbar spine compression fractures, and an F-FDG PET/CT scan was requested to assess for skeletal metastatic disease and potential detection of a primary neoplasm. The PET/CT examination revealed scattered FDG-avid pulmonary opacities with upper lobe preponderance highly suspicious for COVID-19. Read More

World Neurosurg 2020 Jun 2. Epub 2020 Jun 2.

Department of anatomy, Southern Medical University.

Background: The most common complication of oblique lumbar interbody fusion (OLIF) is endplate fracture/subsidence. The mechanics of endplate fracture in OLIF surgery are still unclear. The aim of this study was to evaluate the biomechanical stability in patients undergoing OLIF surgery with stand-alone (SA) methods and bilateral pedicle screw fixation (BPSF). Read More

Medicine (Baltimore) 2020 May;99(21):e20276

Department of Spine Surgery, Affiliated Hospital of Chengde Medical University, Shuangqiao District, Chengde, Hebei Province.

Rationale: The most common fractures of the spine are associated with the thoracolumbar junction (T10-L2). And burst fractures make up 15% of all traumatic thoracolumbar fractures, which are often accompanied by neurological deficits and require open surgeries. Common surgeries include either anterior, posterior or a combination of these approaches. Read More

Bone 2020 May 29;137:115438. Epub 2020 May 29.

Department of Orthopaedic Surgery, Vanderbilt University Medical Center, 1215 21(st) Ave. S., Suite 4200, Nashville, TN 37232, USA; Center for Bone Biology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Biomedical Engineering, Vanderbilt University, 5824 Stevenson Center, Nashville, TN 37232, USA; Department of Veterans Affairs, Tennessee Valley Healthcare System, 1310 24(th) Ave. S., Nashville, TN 37212, USA. Electronic address:

The likelihood of experiencing an osteoporotic fracture of one or more vertebral bodies increases with age, and this increase is not solely due to sex steroid deficiency. For the purpose of assessing the effectiveness of novel therapeutic strategies in the prevention of vertebral fractures among the elderly, we hypothesized that the BALB/c mouse model of aging phenocopies the age-related decrease in human VB strength. To test this hypothesis, we assessed the age-related changes in trabecular architecture of the L6 VB, with respect to those in the distal femur metaphysis, between 6-mo. Read More

Spine J 2020 May 28. Epub 2020 May 28.

Department of Neurosurgery, Johns Hopkins University School of Medicine, 600 N. Wolfe St, Meyer 5-185A, Baltimore, MD 21287, USA. Electronic address:

Background: Current evidence suggests that dual-energy x-ray absorptiometry (DXA) scans, the conventional method defining osteoporosis, is underutilized and, when used, may underestimate patient risk for skeletal fragility. It has recently been suggested that other imaging modalities may better estimate bone quality, such as the magnetic resonance imaging (MRI)-based vertebral bone quality (VBQ) score which also may assess vertebral compression fracture risk in patients with spine metastases.

Purpose: To evaluate whether VBQ score is predictive of fragility fractures in a population with pre-existing low bone density and at high-risk for fracture. Read More

J Korean Neurosurg Soc 2020 May 27. Epub 2020 May 27.

Department of Radiology, Seoul National University Bundang Hospital, Seongnam, Korea.

Objective: To evaluate the effectiveness and long-term outcome predictors of percutaneous sacroplasty (PSP).

Methods: This single-center study assessed 40 patients with sacral insufficiency fractures using the short-axis technique under C-arm flat-panel detector computed tomography (CT). Two radiologists reviewed the patients' magnetic resonance and CT images to obtain imaging findings before PSP and determine technical success, respectively. Read More

Zhongguo Gu Shang 2020 May;33(5):459-64

Department of Orthopaedics, Traditional Chinese Medical Hospital of Xiaoshan, Jiangnan Hospital, Zhejiang University of Traditional Chinese Medicine, Hangzhou 311201, Zhejiang, China.

Objective: To investigate the clinical outcome of single or double-segment pedicle subtraction osteotomy (PSO) for the treatment of old thoracolumbar osteoporotic compression fractures with kyphosis.

Methods: The clinical data of 26 patients with old thoracolumbar osteoporotic compression fractures with kyphosis who underwent surgery from January 2015 to June 2017 were retrospectively analyzed. There were 12 males and 14 females, aged from 58 to 72 years old with an average of 65. Read More

Zhongguo Gu Shang 2020 May;33(5):445-8

Department of Traumatology and Orthopaedics, Yanjishan Hospital, Wannan Medical College, Wuhu 241000, Anhui, China.

Objective: To investigate the influencing factors of hidden blood loss (HBL) during the treatment of percutaneous vertebroplasty (PVP).

Methods: The clinical data of 125 patients with osteoporotic vertebral compression fractures (OVCFs) treated with percutaneous vertebroplasty from March 2016 to December 2017 were retrospectively analyzed. All patients underwent X rays of the AP and lateral lumbar spine, double oblique, and dynamic positions. Read More

Oper Orthop Traumatol 2020 Jun 23;32(3):180-191. Epub 2020 May 23.

Zentrum für Wirbelsäulenchirurgie und Neurotraumatologie, Berufsgenossenschaftliche Unfallklinik Frankfurt am Main, Friedberger Landstr. 430, 60389, Frankfurt am Main, Deutschland.

Objective: Instrumented fusion of lumbar motion segments using a minimally invasive technique.

Indications: Degenerative disc disease, segmental degeneration, degenerative spondylolisthesis, isthmic spondylolisthesis, pseudarthrosis, other spinal lumbar instabilities, disc prolapse, revision for failed back surgery syndrome, unilateral neuroforaminal stenosis, facet joint arthrosis.

Contraindications: High-grade spondylolisthesis (Meyerding grades III/IV, spondyloptosis), bilateral nerve root compression, vertebral fractures, tumors, high-grade spinal instabilities, primary spinal deformities, multilevel pathologies. Read More

Spine J 2020 May 19. Epub 2020 May 19.

Department of Biomedical Engineering, University of Melbourne, Melbourne, Victoria, Australia. Electronic address:

Background Context: While burst fracture is a well-known cause of spinal canal occlusion with dynamic, axial spinal compression, it is unclear how such loading mechanisms might cause occlusion without fracture.

Purpose: To determine how spinal canal occlusion during dynamic compression of the lumbar spine is differentially caused by fracture or mechanisms without fracture and to examine the influence of spinal level on occlusion.

Study Design: A cadaveric biomechanical study. Read More

J Opioid Manag 2020 May/Jun;16(3):215-218

Department of Anesthesiology and Pharmacology, Louisiana State University School of Medicine, New Or-leans, Louisiana.

Objective: Two patient case reports are presented describing the use of cannabidiol (CBD) for the symptomatic relief of a lumbar compression fracture and in the mitigation of thoracic discomfort and dysesthesia secondary to a surgically resected meningioma.

Discussion: CBD appears to have antisnociceptive and anti-inflammatory effects on opioid-naive patients with neuro-pathic and radicular pain. Of note, the patients in this case series used the same CBD cream: Baskin Essentials Body Wellness Cream (400 mg CBD per two oz. Read More

J Sports Sci Med 2020 Jun 1;19(2):237-244. Epub 2020 May 1.

Mie Prefectural College of Nursing, Faculty of Nursing, Tsu, Mie, Japan.

Unlike the lumbar spine and femur, the radius does not bear a gravitational mechanical compression load during daily activities. The distal radius is a common fracture site, but few studies have addressed the effects of exercise on fracture risk. The aim of this study was to determine the effects of the pole push-off movement of Nordic walking (NW) on the bone mineral content (BMC) and areal bone mineral density (aBMD) of the distal radius and the muscle cross-sectional area (CSA) at the mid-humeral and mid-femoral levels. Read More

Cardiovasc Intervent Radiol 2020 Jul 7;43(7):1041-1048. Epub 2020 May 7.

Department Interventional Radiology Unit, Imaging Department, Gustave Roussy Cancer Campus, 114 rue Edouard Vaillant, 94805, Villejuif, France.

Purpose: To assess safety and efficacy of multi-level vertebroplasty, when treating 6 or more levels in the same procedural setting for the management of osteoporotic vertebral compression fractures (oVCF) in cancer patients.

Materials And Methods: Single institution retrospective review from 2015 to 2019 of patients treated for multi-level oVCF in a single session procedural setting by vertebroplasty of 6 or more levels. Procedure outcomes collected included procedural complications, pre- and 4 week post-procedure pain score by numeric rating scale, opioid usage, and vertebral height changes. Read More

Eur Heart J Case Rep 2020 Apr 29;4(2):1-4. Epub 2020 Feb 29.

Division of Cardiovascular Medicine, Department of Internal Medicine, Tokai University School of Medicine, Shimokasuya 143, Isehara-shi, Kanagawa 259-1193, Japan.

Background: Platypnoea-orthodeoxia syndrome (POS) is characterized by dyspnoea and arterial desaturation in the sitting position. Although its pathophysiology is complex and still needed to be investigated, the disease is one of the clinical situations which should be immediately and adequately managed by health care workers from the initial presentation.

Case Summary: A 66-year-old woman with a history of systemic lupus erythematosus, deep vein thrombosis, and lumbar compression fracture was admitted for evaluation of the sudden onset of dyspnoea, while in the sitting position that was relieved on placing her in the supine position. Read More

BMC Surg 2020 Apr 15;20(1):74. Epub 2020 Apr 15.

Department of Orthopedics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Shuaifuyuan No. 1, Wangfujing, Dongcheng District, Beijing, 100730, China.

Background: Percutaneous kyphoplasty (PKP) has become an important minimally invasive surgical technique for fracture stabilization and pain relief in patients with vertebral compression fractures. However, intraspinal cement leakage following PKP is a serious postoperative complication that can lead to morbidity and mortality.

Case Presentation: We describe an uncommon case of epidural leakage of bone cement in an 81-year-old woman who underwent posterior lumbar decompression and fusion from L3-5 4 years prior and had an unremarkable postoperative course. Read More

Cureus 2020 Mar 14;12(3):e7273. Epub 2020 Mar 14.

Neurosurgery, Mayo Clinic, Jacksonville, USA.

Osteoporosis is a common cause of vertebral compression fractures. Often times affecting post-menopausal women, these fractures may occur spontaneously or following minor trauma and are typically managed non-surgically. Here we present a case of a 67-year-old patient who presented with acute compression fracture of the lumbar 5 vertebra and bilateral pedicle fractures of the fourth and fifth lumbar vertebrae following an episode of coughing secondary to tracheitis. Read More

Bone 2020 Jul 11;136:115362. Epub 2020 Apr 11.

Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia; School of Allied Health Sciences, Griffith University, Gold Coast, Queensland, Australia; The Bone Clinic, Brisbane, Queensland, Australia. Electronic address:

Introduction: Few data exist on the effects of bone-targeted exercise on geometric and biomechanical indices of bone strength in men. The Lifting Intervention For Training Muscle and Osteoporosis Rehabilitation for Men (LIFTMOR-M) trial was designed to compare the efficacy and safety of two novel, supervised, twice-weekly, high-intensity exercise programs in middle-aged and older men with osteopenia and osteoporosis on musculoskeletal health and risk factors related to falls and fractures. The current report includes secondary outcomes of the LIFTMOR-M exercise intervention trial. Read More

J Geriatr Phys Ther 2020 Apr 8. Epub 2020 Apr 8.

Department of Rehabilitation, Teikyo University School of Medicine University Hospital, Kawasaki, Kanagawa, Japan.

Background And Purpose: Most patients become physically inactive after vertebral compression fracture and thus need help for early mobilization. This study sought to investigate the effect of early rehabilitation on activities of daily living in patients following acute vertebral compression fracture.

Methods: We conducted this retrospective cohort study with a hospital-based database created by the Japan Medical Data Center and comprising data from a Diagnosis Procedure Combination survey from more than 100 acute care hospitals across Japan. Read More

Gerontol Geriatr Med 2020 Jan-Dec;6:2333721420914771. Epub 2020 Mar 25.

University of Tsukuba, Ibaraki, Japan.

Bone densitometry is widely used to evaluate osteoporosis; however, it is pointed out that bone density may be high in the case of fractures, deformities, and osteosclerotic changes. The present study evaluated bone density measured at our hospital and evaluated its correlation with the presence or absence of lumbar spine fractures. Bone density of the lumbar spine and femur was measured in 185 patients from July 2017 to June 2019 at our hospital, and the presence or absence of a lumbar spine compression fracture was evaluated on the basis of the image. Read More

Diagnostics (Basel) 2020 Mar 27;10(4). Epub 2020 Mar 27.

Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Daegu 42415, Korea.

A 77-year-old woman having back pain due to an L2 vertebral body compression fracture took a lumbar spine magnetic resonance imaging (MRI). In MRI, in addition to the L2 vertebral body fracture, invagination of the small intestine into the intervertebral disc space at L5-S1 was found by chance. On a lateral lumbar spinal X-ray, the lordotic angle was markedly increased at the L5-S1 level. Read More

JOR Spine 2020 Mar 19;3(1):e1078. Epub 2020 Jan 19.

Department of Mechanical Engineering University of California Berkeley California.

Adverse clinical outcomes for total disc arthroplasty (TDA), including subsidence, heterotopic ossification, and adjacent-level vertebral fracture, suggest problems with the underlying biomechanics. To gain insight, we investigated the role of size and stiffness of TDA implants on load-transfer within a vertebral body. Uniquely, we accounted for the realistic multi-scale geometric features of the trabecular micro-architecture and cortical shell. Read More

JOR Spine 2020 Mar 3;3(1):e1077. Epub 2020 Feb 3.

Institute of Medical and Biological Engineering, Mechanical Engineering University of Leeds Leeds UK.

Vertebroplasty has been widely used for the treatment of osteoporotic compression fractures but the efficacy of the technique has been questioned by the outcomes of randomized clinical trials. Finite-element (FE) models allow an investigation into the structural and geometric variation that affect the response to augmentation. However, current specimen-specific FE models are limited due to their poor reproduction of cement augmentation behavior. Read More

Lancet Neurol 2020 04 18;19(4):298-306. Epub 2020 Mar 18.

Clinical Research Centre and Department of Neurology, National Hospital Organization Utano National Hospital, Kyoto, Japan.

Background: Pharmacological prevention against relapses in patients with neuromyelitis optica spectrum disorder (NMOSD) is developing rapidly. We aimed to investigate the safety and efficacy of rituximab, an anti-CD20 monoclonal antibody, against relapses in patients with NMOSD.

Methods: We did a multicentre, randomised, double-blind, placebo-controlled clinical trial at eight hospitals in Japan. Read More

Medicine (Baltimore) 2020 Mar;99(12):e19578

Department of Spine Surgery, The First Hospital of Jilin University.

Introduction: Spondyloptosis is a form of vertebral dislocation and the most advanced form of spondylolisthesis. Traumatic spondyloptosis is usually caused by high-energy impact and results in unstable spine deformity and spinal canal deformation, which lead to severe spinal cord injury. Traumatic spondyloptosis is mostly reported in the lumbo-sacral junction, while it is rarely documented in mid-lumbar segments. Read More

Gene 2020 May 9;741:144543. Epub 2020 Mar 9.

Shanghai Clinical Research Center of Bone Disease, Department of Osteoporosis and Bone Diseases, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China. Electronic address:

Introduction: Collagen cross-linking, which is regulated by lysyl oxidase (LOX), plays critical roles in bone mechanical strength. LOX can influence bone remodeling by modulating osteoblast and osteoclast activity. This study aimed to explore the effect of LOX gene polymorphisms on osteoporotic fractures susceptibility in postmenopausal Chinese women. Read More

Case Rep Orthop 2020 22;2020:7372821. Epub 2020 Feb 22.

Department of Spinal Surgery, Kameda Medical Center, 929 Higashi-cho, Kamogawa-shi, Chiba 296-8602, Japan.

Spinal subdural abscesses are rare lesions. We report the case of surgical site infection complicated with meningitis and rapidly progressive spinal subdural abscess caused by following transforaminal lumbar interbody fusion (TLIF). A 72-year-old woman was admitted to our hospital complaining of drop foot syndrome and sciatica caused by stenosis of the L5/6 intervertebral foramen accompanied by L5 lumbar vertebral fracture. Read More

Spine (Phila Pa 1976) 2020 Mar 6. Epub 2020 Mar 6.

Department of Neurosurgery, Koç University Hospital, Istanbul, Turkey.

Study Design: Technique note OBJECTIVE.: To evaluate the feasibility of endoscopy in various spinal pathologies SUMMARY OF BACKGROUND DATA.: Osteoporotic vertebral fractures are a common pathology in the elderly. Read More

World Neurosurg 2020 Jun 3;138:e354-e360. Epub 2020 Mar 3.

Department of Neurosurgery, Istanbul University Faculty of Medicine, Istanbul, Turkey.

Objective: The aim to evaluate central sarcopenia, as measured by psoas cross-sectional area on admission imaging, is associated with outcomes in patients with vertebral compression fractures (VCFs) treated with percutaneous vertebral augmentation treatment.

Methods: We evaluated the records of patients aged >60 years treated with vertebroplasty or kyphoplasty between 2009 and 2018 for osteoporotic VCFs. The Social Security Death Index was used to determine death. Read More

Zhongguo Gu Shang 2020 Feb;33(2):111-5

Department of Orthopaedics, the First People's Hospital of Huzhou, Huzhou 313000, Zhejiang, China.

Objective: To investigate the guiding significance of lumbar quantitative computed tomography (QCT) in percutaneous vertebroplasty (PKP) for osteoporotic vertebral compression fractures (OVCF).

Methods: The clinical data of 90 patients with OVCF underwent PKP from December 2017 to December 2018 were retrospectively analyzed. There were 24 femalesand66males, withanaverage agedof (74. Read More

Int J Spine Surg 2020 Feb 10;14(Suppl 1):3-13. Epub 2020 Feb 10.

Engineering Center for Orthopaedic Research Excellence (E-CORE), Departments of Bioengineering and Orthopaedics, The University of Toledo, Toledo, Ohio.

Background: The sacroiliac joints (SIJs), the largest axial joints in the body, sit in between the sacrum and pelvic bones on either side. They connect the spine to the pelvis and thus facilitate load transfer from the lumbar spine to the lower extremities. The majority of low back pain (LBP) is perceived to originate from the lumbar spine; however, another likely source of LBP that is mostly overlooked is the SIJ. Read More

Spine J 2020 Feb 24. Epub 2020 Feb 24.

Spine lab, Department of Orthopedic Surgery, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. Electronic address:

Background Context: Although vertebral augmentation with bone cement has been commonly used to treat symptomatic osteoporotic vertebral compression fractures, relatively little is known about the impact of augmentation on the adjacent spinal components.

Purpose: To determine the imaging effects of vertebral augmentation on the adjacent discs, the augmented vertebra, and the involved spinal segment.

Study Design: Retrospective radiographic study. Read More

IDCases 2020 20;19:e00687. Epub 2019 Dec 20.

Department of Emergency Medicine, Shin Yurigaoka General Hospital, 255 Furusawatuko Asou-ku, Kawasaki, Kanagawa, 247-8581 Japan.

An 83-year-old man visited an orthopedic hospital for his lower back pain. A compression fracture was noted in his second lumbar vertebra. He had taken pain medication for approximately five weeks, but the pain had worsened and he was unable to walk by himself. Read More

Radiol Med 2020 Jun 17;125(6):551-560. Epub 2020 Feb 17.

Department of Studies in Computer Science, University of Mysore, Manasagangotri, Mysore, Karnataka, 570006, India.

Vertebral fractures are important indicators of osteoporosis. Fractures with partial collapse of vertebral bodies are referred to as vertebral compression fractures (VCFs) that are usually non-traumatic in nature. Some common causes of VCFs are trauma, bone failure related to osteoporosis (benign) and metastatic cancer (malignant). Read More

Medicine (Baltimore) 2020 Feb;99(7):e19037

Department of Neurosurgery, Chonnam National University Hospital and Medical School, Gwangju, Republic of Korea.

Rationale: We present a rare case of a traumatic intradural ruptured disc associated with a mild vertebral body compression fracture along with a review of the relevant medical literature. An intradural ruptured disc often occurs due to chronic degenerative diseases and is rarely due to trauma. It can cause irreversible neurological complications if the appropriate treatment is not planned. Read More

Spine (Phila Pa 1976) 2020 Jul;45(13):895-902

Department of Orthopaedics, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.

Study Design: Prospective cohort study.

Objective: To characterize a patient population with nonunion after acute osteoporotic vertebral fractures (OVFs) and compare the union and nonunion groups to identify risk factors for nonunion.

Summary Of Background Data: While OVFs are the most common type of osteoporotic fracture, the predictive value of a clinical assessment for nonunion at 48 weeks after OVF has not been extensively studied. Read More

J Clin Densitom 2020 Jan 11. Epub 2020 Jan 11.

Department of Physical Education, Division of Education, Faculty of Arts and Sciences, University of Balamand, Kelhat El-Koura, Lebanon. Electronic address:

The aim of the present study was to explore the influence of physical activity level on composite indices of femoral neck strength (compression strength index [CSI], bending strength index, and impact strength index) in a group of young overweight men. To do so, we compared composite indices of femoral neck strength in active overweight men and insufficiently active overweight men. They were divided into 2 groups based on their physical activity level: 70 active overweight men (engaging in more than 150 minutes of physical activity per week; 8. Read More

Medicine (Baltimore) 2020 Feb;99(6):e19053

Department of Spine Surgery, The Third Hospital of Shijiazhuang, Shijiazhuang, China.

Rationale: Traditionally, transpedicular approach was used in the treatment of osteoporotic lumbar compression fracture. In order to avoid the risks of pedicle disruption and spinal canal intrusion, extrapedicular approache has been attempted. The aim of the article is to present the modified extrapedicular kyphoplasty technique for the treatment of osteoporotic lumbar compression fracture. Read More

Bone 2020 May 3;134:115261. Epub 2020 Feb 3.

Shriners Hospital for Children - Canada, McGill University, Montreal, QC, Canada.

Heterozygous mutations in the gene encoding the sphingomyelin synthase 2, SGMS2, have recently been linked to childhood-onset osteoporosis and skeletal dysplasia. One nonsense variant at position c.148C>T (p. Read More

Praxis (Bern 1994) 2020 Feb;109(2):87-95

Facharzt FMH Neurochirurgie, c/o Neuromed, Zürich.

Everyone Has Low Back Pain: Degenerative Lumbar Spinal Disorders and Their Treatment Options Back pain is one of the most widespread diseases. Up to 84 % of people have low back pain at some point in their lives. Unspecific back pain is treated conservatively. Read More

World Neurosurg 2020 May 31;137:e286-e290. Epub 2020 Jan 31.

Department of Neurosurgery, Tulane Center for Clinical Neurosciences, Tulane University School of Medicine, New Orleans, Louisiana, USA; Department of Anatomical Sciences, St. George's University, St. George's, Grenada; Department of Structural & Cellular Biology, Tulane University School of Medicine, New Orleans, Louisiana, USA; Department of Neurosurgery and Ochsner Neuroscience Institute, Ochsner Health System, New Orleans, Louisiana, USA.

Background: Bone cement augmentation with polymethylmethacrylate is a reliable method for stabilizing osteoporotic compression fractures and improving fixation of pedicle screws. However, cement extrusion into the vertebral venous system can result in pulmonary cement embolism. The goal of this anatomic study was to identify the relationship between the internal/external vertebral plexus and neighboring abdominal caval system. Read More

PLoS One 2020 30;15(1):e0228341. Epub 2020 Jan 30.

Department of Spine Surgery, Shandong Provincial Hospital affiliated to Shandong University, Jinan, P.R. China.

Background: Osteoporotic vertebral compression fractures (OVCFs) often cause local kyphosis. Percutaneous kyphoplasty (PKP) is a common method for the treatment of local kyphosis. However, the influence of kyphoplasty on spino-pelvic alignment and global sagittal balance when performed at specific treatment sites in the spine remains unclear. Read More

Asian Spine J 2020 Jan 30. Epub 2020 Jan 30.

Department of Orthopedics and Traumatology, Dokuz Eylul University School of Medicine, Izmir, Turkey.

Study Design: Biomechanical study.

Purpose: This study investigates the benefits of supplemental hook fixation (SHF) on short-segment pedicle instrumentation (SSPI) in relation to anterior strut graft positioning. In addition, it seeks to determine whether the integrity of the posterior ligamentous complex (PLC) affects the stability of the spinal construct. Read More

Biomed Res Int 2019 26;2019:4780426. Epub 2019 Dec 26.

Department of Orthopedics Surgery, Bone and Joint Research Center, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan.

Background: For thoracolumbar burst fractures, traditional four-screw (one above and one below) short-segment instrumentation is popular and has a high failure rate. Additional augmentation at the fractured vertebrae is believed to reduce surgical failure. The purpose of this study was to examine the clinical and radiographic results of patients who underwent short-segment posterior instrumentation with augmentation by screws and bone substitutes at the fractured vertebrae and to compare these data to those of patients who underwent long-segment instrumentation for thoracolumbar burst fractures. Read More