2,167,494 results match your criteria Low Energy Availability in the Female Athlete


[The UroLift® system for treatment of the benign prostatic syndrome (BPS)].

Aktuelle Urol 2018 Dec 6;49(6):515-518. Epub 2018 Dec 6.

Klinikum Großhadern/Innenstadt, Ludwig-Maximilians-Universität München, Urologische Klinik und Poliklinik, München.

Minimally-invasive treatment options for patients with LUTS due to benign prostatic obstruction (BPO) become more and more important because they provide equal long-term efficacy compared with the reference method TURP, while having a more favourable safety profile. There are promising results for PUL (Prostatic Urethral Lift - UroLift) with low complication rates. UroLift is clearly superior regarding the preservation of sexual functions without impairment of ejaculatory function. Read More

View Article
December 2018
6 Reads

Hypercortisolism in Newly Diagnosed Type 2 Diabetes: A Prospective Study of 384 Newly Diagnosed Patients.

Horm Metab Res 2018 Dec 6. Epub 2018 Dec 6.

Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark.

Cross-sectional studies in small and selected populations report a high prevalence of hypercortisolism in patients with type 2 diabetes (T2D), which could have therapeutic implications, if confirmed. We therefore estimated the prevalence of hypercortisolism in a large and unselected cohort of recently diagnosed T2D patients. Consecutive patients with recently diagnosed T2D first underwent an overnight dexamethasone (1 mg) suppression test (OD). Read More

View Article
December 2018
1 Read

Downregulation of microRNA-376a in Gastric Cancer and Association with Poor Prognosis.

Cell Physiol Biochem 2018 Dec 6;51(5):2010-2018. Epub 2018 Dec 6.

Background/aims: MicroRNAs have a significant role in the tumorigenesis and progression of cancers, including gastric cancer (GC). Our study aimed to identify a novel biomarker to predict the prognosis of patients with GC.

Methods: The GC microarray dataset, GSE28700, was downloaded from the Gene Expression Omnibus (GEO) database and screened for differentially expressed miRNAs (DEMs). Read More

View Article
December 2018
2 Reads

Potential Role of microRNA-183 as a Tumor Suppressor in Hepatocellular Carcinoma.

Cell Physiol Biochem 2018 Dec 6;51(5):2065-2072. Epub 2018 Dec 6.

Department of General Surgery of East District, The Second Hospital of Hebei Medical University, Shijiazhuang,

Background/aims: Disseminated tumors, known as metastases, are responsible for ninety-percent of mortality due to cancer. Epithelial to mesenchymal transition, a phenomenon required for morphological conversion of non-motile discoid shaped epithelial cells to highly motile spindle-shaped mesenchymal cells, is thought to be a pre-requisite for metastatic progression. Metastasis-associated 1 (MTA1) protein is a prime inducer of EMT and metastatic progression in all solid tumors including hepatocellular carcinoma (HCC). Read More

View Article
December 2018
3 Reads

Gliquidone Alleviates Diabetic Nephropathy by Inhibiting Notch/Snail Signaling Pathway.

Cell Physiol Biochem 2018 Dec 6;51(5):2085-2097. Epub 2018 Dec 6.

Background/aims: Diabetic nephropathy is a common complication of diabetes. This study explored the renal protective effect and possible mechanism of gliquidone in mice with diabetic nephropathy.

Methods: Animal model of diabetic nephropathy was established in KKAy mice. Read More

View Article
December 2018
2 Reads

Association of Central Venous Oxygen Saturation Variability and Mortality in Hemodialysis Patients.

Blood Purif 2018 Dec 6:1-8. Epub 2018 Dec 6.

Renal Research Institute, New York, New York,

Background: Central venous oxygen saturation (ScvO2) is correlated with cardiac output. In most patients, ScvO2 declines during hemodialysis (HD) due to factors such as reduced preload, myocardial stunning, and intermittent arrhythmias. Previous research has shown that low ScvO2 is associated with higher mortality in chronic HD patients. Read More

View Article
December 2018

In silico Leishmania proteome mining applied to identify drug target potential to be used to treat against visceral and tegumentary leishmaniasis.

J Mol Graph Model 2018 Nov 29;87:89-97. Epub 2018 Nov 29.

Programa de Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Departamento de Patologia Clínica, COLTEC, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil. Electronic address:

New therapeutic strategies against leishmaniasis are desirable, since the treatment against disease presents problems, such as the toxicity, high cost and/or parasite resistance. As consequence, new antileishmanial compounds are necessary to be identified, as presenting high activity against Leishmania, but low toxicity in mammalian hosts. In the present study, a Leishmania proteome mining strategy was developed, in order to select new drug targets with low homology to human proteins, but that are considered relevant for the parasite' survival. Read More

View Article
November 2018
1 Read

Behavioral problems are associated with cognitive and language scores in toddlers born extremely preterm.

Early Hum Dev 2018 Dec 3;128:48-54. Epub 2018 Dec 3.

Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.

Objective: To evaluate the relationship of parent-reported child behaviors on the Child Behavior Checklist (CBCL) to cognition, language, and motor skills on the Bayley Scales of Infant and Toddler Development - III (Bayley-III) in toddlers born extremely preterm.

Study Design: Toddlers born extremely preterm (gestational ages 22 0/7 to 26 6/7 weeks) were tested at 22-26 months corrected age with Bayley-III while parents completed the CBCL. Socio-demographic variables and medical history were recorded. Read More

View Article
December 2018
3 Reads

Agreement is very low between a clinical prediction rule and physiotherapist assessment for classifying the risk of poor recovery of individuals with acute whiplash injury.

Musculoskelet Sci Pract 2018 Nov 19;39:73-79. Epub 2018 Nov 19.

Menzies Health Institute Queensland, Griffith University, G05, 3.20E Parklands Drive, Southport, 4222, Australia; Recover Injury Research Centre, NHMRC Centre of Research Excellence in Recovery Following Road Traffic Injuries, The University of Queensland, Level 7 Oral Health Centre, 288 Herston Road, Herston, Queensland, 4006, Australia. Electronic address:

Background: A prognostic clinical prediction rule (whiplash CPR) has been validated for use in individuals with acute whiplash associated disorders (WAD). The clinical utility of this tool is unknown.

Objectives: To investigate: 1) the level of agreement between physiotherapist- and whiplash CPR-determined prognostic risk classification of people with acute WAD; 2) which clinical findings are used by physiotherapists to classify prognostic risk; and 3) whether physiotherapists plan to differ the number of treatment sessions provided based on prognostic risk classification. Read More

View Article
November 2018
2 Reads

Measurement of absolute γ-ray emission probabilities in the decay of Ac in equilibrium with its progeny.

Appl Radiat Isot 2018 Aug 30;144:34-46. Epub 2018 Aug 30.

European Commission, Joint Research Centre, Directorate for Nuclear Safety and Security, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany. Electronic address:

The emission probabilities of γ rays produced in the Ac decay series were determined by high-resolution γ-ray spectrometry of sources with standardised activity. The sources were prepared quantitatively on glass discs by drop deposition of a solution with Ac in radioactive equilibrium with its daughter nuclides. Their activity was measured by a primary standardisation technique based on alpha-particle counting at a defined low solid angle. Read More

View Article

Investigating associations between caffeinated beverage consumption and later alcohol consumption among early adolescents.

Addict Behav 2018 Nov 23;90:362-368. Epub 2018 Nov 23.

Department of Psychology, Rutgers University, Camden 311 North 5th Street, Camden NJ 08102, United States. Electronic address:

Previous research has demonstrated that caffeinated beverage consumption predicts alcohol consumption among early adolescents. This study aimed to investigate this association in two ways: (1) by examining if this association remained significant once other established risk factors for alcohol were adjusted for statistically; and (2) by considering three possible moderators of this association: gender, sensation-seeking, and parental monitoring. Data from the Camden Youth Development Study, a longitudinal, community-based study of middle-school students, were used. Read More

View Article
November 2018

Tobacco and cannabis co-use and interrelatedness among adults.

Addict Behav 2018 Nov 27;90:354-361. Epub 2018 Nov 27.

Medical University of South Carolina, Department of Psychiatry and Behavioral Sciences, Charleston, SC, USA.

Cannabis and tobacco co-use is prevalent, but consensus regarding the reasons for co-use among adults and the degree of interrelatedness between these substances is lacking. Reasons for co-use have been explored with younger users, but little data exists for more experienced users with entrenched patterns of co-use. The goal of this study was to examine characteristics and patterns of cannabis-tobacco co-use among adults in the Southeastern United States (US), where there is a legal landscape of generally restrictive cannabis legislation coupled with more permissive tobacco control compared to other US regions. Read More

View Article
November 2018
1 Read

How much of a market is involved in a biodiversity offset? A typology of biodiversity offset policies.

J Environ Manage 2018 Dec 3;232:679-691. Epub 2018 Dec 3.

Stockholm Resilience Centre, Stockholm University, Kräftriket 2B, SE-114 19, Stockholm, Sweden.

Biodiversity offsets (BO) are increasingly promoted and adopted by governments and companies worldwide as a policy instrument to compensate for biodiversity losses from infrastructure development projects. BO are often classified as 'market-based instruments' both by proponents and critics, but this representation fails to capture the varieties of how BO policies actually operate. To provide a framing for understanding the empirical diversity of BO policy designs, we present an ideal-typical typology based on the institutions from which BO is organised: Public Agency, Mandatory Market and Voluntary Offset. Read More

View Article
December 2018

Management of slurry in Gran Canaria Island with full-scale natural treatment systems for wastewater (NTSW). One year experience in livestock farms.

J Environ Manage 2018 Dec 3;232:666-678. Epub 2018 Dec 3.

Institute for Environmental Studies and Natural Resources (i-UNAT), University of Las Palmas de Gran Canaria, Spain. Electronic address:

The aim of this work is to describe the performance of three full-scale natural treatment systems for wastewater, which operated in an integrated manner in livestock pig farms (1000-1500pigsintotal) over one year. Slurry management was performed with these natural treatment systems operating under the normal waste loading conditions of the livestock farms in which were integrated. The systems were comprised of elements such as first generation digesters, subsurface flow constructed wetlands and facultative ponds. Read More

View Article
December 2018
1 Read

An approach to the implementation of Low Impact Development measures towards an EcoCampus classification.

J Environ Manage 2018 Dec 3;232:654-659. Epub 2018 Dec 3.

ECT-School of Science and Technology, University of Trás-os-Montes e Alto Douro UTAD, Quinta de Prados, 5000-801 Vila Real, Portugal; Centre for Transdisciplinary Development Studies, University of Trás-os-Montes e Alto Douro, Quinta de Prados, 5000-801 Vila Real, Portugal.

Impervious cover has important hydrologic impacts, namely the increased runoff volume and peak discharges in the rainwater network, which can lead to significant consequences like rapid urban floods with social, environmental and economic implications. LID (Low Impact Development) consist of distributed runoff management measures, like green roofs, pervious pavements, waterways covered with vegetation and filter trails, among others, that seek to control stormwater in the origin, reducing imperviousness. These solutions avoid increased runoff rate and volume, increase infiltration and groundwater recharge. Read More

View Article
December 2018

Socioeconomic differences among resident, users and neighbour populations of a protected area in the Brazilian dry forest.

J Environ Manage 2018 Dec 3;232:607-614. Epub 2018 Dec 3.

Departamento de Biociências, Universidade Federal Rural do Semiárido, Av. Francisco Mota, 572, Mossoró, Rio Grande do Norte, Brazil. Electronic address:

Protected areas are an important strategy to safeguard biodiversity. However, if social development is not considered, biological conservation targets may not be achieved. In this empirical study, we assess the relationship between poverty and conservation goals in dry forests within a 62,000-ha Brazilian National Park (Caatinga biome). Read More

View Article
December 2018
1 Read

Longer schooling but not better off? A quasi-experimental study of the effect of compulsory schooling on biomarkers in France.

Soc Sci Med 2018 Nov 23;220:379-386. Epub 2018 Nov 23.

Department of Social and Behavioral Sciences, Harvard T H Chan School of Public Health, 677 Huntington Ave, Boston, MA, 02115, USA; CUNY Graduate School of Public Health and Health Policy, 205 East 42nd Street, New York, NY, 10017, USA.

Less schooling is associated with increased biological risks for chronic disease, but whether increasing years of schooling through policy interventions reduces these risks remains unclear. We examine the effect of a major education reform introduced in 1959 that raised the minimum school leaving age from 14 to 16 years in France, offering a unique natural experiment. We assess the causal impact of increased schooling duration on 16 biomarkers of cardiovascular, metabolic, organ and immune function in a large cohort of men and women born around 1953. Read More

View Article
November 2018
4 Reads

Impairment of the antifibrotic prostaglandin E pathway may influence neutrophil extracellular traps-induced fibrosis in the mare endometrium.

Domest Anim Endocrinol 2018 Nov 3;67:1-10. Epub 2018 Nov 3.

Department of Morphology and Function, CIISA- Centre for Interdisciplinary Research in Animal Health, Faculty of Veterinary Medicine, University of Lisbon, Lisbon, Portugal.

Prostaglandin E (PGE) has contradictory effects in many organs. It may have proinflammatory, anti-inflammatory, or anti-fibrotic roles, depending on the type of receptors to which it binds. By signaling through its receptors EP2 and EP4, PGE mediates anti-inflammatory and anti-fibrotic actions. Read More

View Article
November 2018
2 Reads

Neuroprotective effects of a novel carnosine-hydrazide derivative on hippocampal CA1 damage after transient cerebral ischemia.

Eur J Med Chem 2018 Nov 28;163:207-214. Epub 2018 Nov 28.

Department of Neurosurgery, Kurume University, School of Medicine, Fukuoka, Japan. Electronic address:

Ischemia-reperfusion injuries produce reactive oxygen species that promote the peroxide lipid oxidation process resulting in the production of an endogenic lipid peroxide, 4-hydroxy-trans-2-nonenal (4-HNE), a highly cytotoxic aldehyde that induces cell death. We synthesized a novel 4-HNE scavenger - a carnosine-hydrazide derivative, l-carnosine hydrazide (CNN) - and examined its neuroprotective effect in a model of transient ischemia. PC-12 cells were pre-incubated with various doses (0-50 mmol/L) of CNN for 30 min, followed by incubation with 4-HNE (250 μM). Read More

View Article
November 2018
1 Read

Highly effective and safe intermediate based on deep eutectic medium for carrier less-three phase hollow fiber microextraction of antiarrhythmic agents in complex matrices.

J Chromatogr B Analyt Technol Biomed Life Sci 2018 Nov 7;1104:196-204. Epub 2018 Nov 7.

Department of Chemistry, Semnan University, Semnan 35195-363, Iran.

For the first time, three phase hollow fiber liquid phase microextraction using an influential, and green middle phase comprised a new relatively-hydrophobic deep eutectic solvent (three-phase HF-LPME-DES) was developed for trace analyses of antiarrhythmic drugs in biological and environmental samples. The extraction solvent was easily synthesized by mixing the green and cheap raw materials, namely choline chloride and 1-phenylethanol (ChCl: Ph-ETOH), in the ambient temperature. Good compatibility to pores of hollow-fiber, high ability for extraction of ionizable organic compounds with no need to any carrier agents, and easy availability in the laboratory environment turned this new proposed deep eutectic intermediate to a worthy generation of the supported liquid membrane (SLM). Read More

View Article
November 2018
2 Reads

Does exclusive breastfeeding relate to the longer duration of breastfeeding? A prospective cohort study.

Midwifery 2018 Nov 19;69:163-171. Epub 2018 Nov 19.

Department of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA. Electronic address:

Objectives: Suboptimal breastfeeding contributes to morbidity and mortality in children. Studies in high-income countries (HICs) show that exclusive-breastfeeding (EBF) is associated with longer breastfeeding duration. The aim of this study was to determine whether maternal reports of EBF at six months are associated with longer duration of breastfeeding during the first two years of life in a low and middle-income country (LMIC) setting, and to identify determinants of breastfeeding duration. Read More

View Article
November 2018

Social support and second trimester depression.

Midwifery 2018 Nov 23;69:158-162. Epub 2018 Nov 23.

Nursing Department of Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, No.2699, West Gaoke Road, Pudong New Area, Shanghai 201204, China.

Background: Depression is the most prevalent psychiatric disease during and after pregnancy (Aktas and Yesilcicek, 2015). Social supportive system (SSS) serves to protect against the development of depressive symptoms (Moshki and Cheravi, 2016). The mitigating effect of SSS on depression among expectant Chinese women is unclear. Read More

View Article
November 2018
1 Read

Quantifying streamflow response to climate variability, wastewater inflow, and sprawling urbanization in a heavily modified river basin.

Sci Total Environ 2018 Nov 23;656:458-467. Epub 2018 Nov 23.

Department of Hydrology, Faculty of Geography and Regional Studies, University of Warsaw, Krakowskie Przedmieście 30, 00-927 Warsaw, Poland. Electronic address:

Considering the growing recognition that human activity and climate variability are critical stressors influencing river regimes, there is an urgent need to identify the contribution of these fundamental factors. Here we examine the runoff changes of a wastewater-effluent dominated river flowing in a heavily modified urban environment. The study concerns the Utrata River basin (727 km), central Poland, a challenging human-natural system for investigating changes in hydrological processes. Read More

View Article
November 2018

A sensitive biosensing method for detecting of ultra-trace amounts of AFB1 based on "Aptamer/reduced graphene oxide" nano-bio interaction.

Colloids Surf B Biointerfaces 2018 Dec 1;175:98-105. Epub 2018 Dec 1.

Department of Chemistry, Payame Noor University (PNU), P.O. Box: 19395-4697, Tehran, Iran. Electronic address:

A simple, low-cost and sensitive label-free aptasensor assembled with assisting reduced graphene oxide nanosheets as the signal amplifier was fabricated and applied for detecting ultra-low levels of Aflatoxin B1(AFB1) through a nano-bio interaction system. The conditions of different modified glassy carbon electrodes as the base of aptasensor were investigated by cyclic voltammetry (CV), differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS). The performance of the fabricated aptasensor was evaluated by FESEM, HRTEM and AFM images. Read More

View Article
December 2018

Elaboration of a thermosensitive smart biomaterial: From synthesis to the ex vivo bioadhesion evaluation.

Colloids Surf B Biointerfaces 2018 Nov 30;175:91-97. Epub 2018 Nov 30.

CIRIMAT, Université de Toulouse 3 - Paul Sabatier, CNRS, Toulouse, France. Electronic address:

Alginate and chitosan are polysaccharides that are widely used in the biomedical field, especially as wound dressings. Controlled bioadhesion is an advanced functionality that offers the potential to reduce injuries due to the stripping-off of the biomaterial. Herein, we report the efficient grafting of poly-N(isopropylacryamide) (PNIPAM), a thermosensitive polymer that exhibits a lower critical solution temperature (LCST) at 32 °C on the alginate/chitosan polyelectrolyte complex (PEC) surface. Read More

View Article
November 2018

Impact of short-term traffic-related air pollution on the metabolome - Results from two metabolome-wide experimental studies.

Environ Int 2018 Dec 3;123:124-131. Epub 2018 Dec 3.

MRC/PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom; Italian Institute for Genomic Medicine (IIGM), Turin, Italy. Electronic address:

Exposure to traffic-related air pollution (TRAP) has been associated with adverse health outcomes but underlying biological mechanisms remain poorly understood. Two randomized crossover trials were used here, the Oxford Street II (London) and the TAPAS II (Barcelona) studies, where volunteers were allocated to high or low air pollution exposures. The two locations represent different exposure scenarios, with Oxford Street characterized by diesel vehicles and Barcelona by normal mixed urban traffic. Read More

View Article
December 2018
1 Read

Ultrasonic torsion welding of ageing-resistant Al/CFRP joints: Properties, microstructure and joint formation.

Ultrasonics 2018 Nov 22;93:139-144. Epub 2018 Nov 22.

University of Freiburg, Walter and Ingeborg Herrmann Professorship for Engineering of Functional Materials (EFM), Department for Sustainable Systems Engineering (INATECH), Faculty of Engineering, 79110 Freiburg, Germany.

Ultrasonic metal welding is a promising process for joining light metals with fiber-reinforced thermoplastics. The technique is characterized by high reproducibility, short process times, low energy input, no additional filler materials and finally the possibility of extensive process data logging. With this process, dissimilar aerospace materials are ultrasonically welded and the applied process parameters are optimized by statistical methods. Read More

View Article
November 2018
2 Reads

Early impact of pulmonary stereotactic fractionated body radiotherapy (SBRT) on Quality of Life (QoL): Benefit for patients with low initial scores (STRIPE trial).

J Thorac Oncol 2018 Dec 3. Epub 2018 Dec 3.

Department of Radiation Oncology, Medical Center, Faculty of Medicine, University of Freiburg, Germany; German Cancer Consortium (DKTK) Partner Site Freiburg, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany.

Introduction: Quality of life (QoL) of comorbid patients with pulmonary malignancies is a key issue in considering stereotactic fractionated body radiotherapy (SBRT) indication. This study investigates the early impact of SBRT on QoL.

Methods: 100 patients with pulmonary lesions were treated with SBRT from 02/2011 to 11/2014 within the prospective, monocenter, phase II STRIPE trial. Read More

View Article
December 2018
1 Read

Enrichment of common carp (Cyprinus carpio) fingerlings diet with Psidium guajava: The effects on cutaneous mucosal and serum immune parameters and immune related genes expression.

Fish Shellfish Immunol 2018 Dec 3. Epub 2018 Dec 3.

Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand. Electronic address:

The present study aimed at evaluation of possible effects of Psidium guajava as immunostimulant on mucosal and serum immunity, as well as related genes expression in common carp (Cyprinus carpio) fingerlings. In an eight weeks feeding trial, fish were fed with experimental diets containing guava leaf powder [GLP] (0, 0.25, 0. Read More

View Article
December 2018
4 Reads

Carotid Endarterectomy for Medical Therapy-resistant Symptomatic Low-grade Stenosis.

World Neurosurg 2018 Dec 3. Epub 2018 Dec 3.

Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Background: Plaque characteristics play pivotal roles in ischemic events, but stenosis severity does not accurately reflect carotid plaque volume due to expansive remodeling in some patients with low-grade stenosis (LGS).

Objective: This study aimed to assess the safety, efficacy, and durability of carotid endarterectomy (CEA) for symptomatic LGS.

Methods: Study participants comprised 61 consecutive patients who underwent CEA for symptomatic carotid stenosis. Read More

View Article
December 2018

Radiochemical synthesis and preclinical evaluation of Ga-labeled NODAGA-hydroxypropyl-beta-cyclodextrin (Ga-NODAGA-HPBCD).

Eur J Pharm Sci 2018 Dec 3. Epub 2018 Dec 3.

Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Debrecen, Nagyerdei St. 98, H-4032 Debrecen, Hungary. Electronic address:

A new renaissance started in the research and application of cyclodextrins a few years ago. 2-Hydroxypropyl-beta-cyclodextrin (HPBCD) is used in the formulation of drugs and recently orphan designation was granted for the treatment of Niemann-Pick disease, type C. HPBCD is considered to be safe, but the exact mechanism of action and side effects are not completely explained. Read More

View Article
December 2018

Ecological niche modeling as a tool for prediction of the potential geographic distribution of Bacillus anthracis spores in Tanzania.

Int J Infect Dis 2018 Dec 3. Epub 2018 Dec 3.

Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Oslo, Norway.

Introduction: Anthrax is caused by the spore-forming, Gram-positive bacterium Bacillus anthracis. The aim of the study was to predict the potential distribution of B. anthracis in Tanzania and produce epidemiological evidence for management of anthrax outbreaks in the country. Read More

View Article
December 2018
1 Read
2.330 Impact Factor

Preparation and characterization of poly(ε-caprolactone) scaffolds modified with cell-loaded fibrin gel.

Int J Biol Macromol 2018 Dec 3. Epub 2018 Dec 3.

Middle East Technical University (METU), BIOMATEN Center of Excellence in Biomaterials and Tissue Engineering, Ankara 06800, Turkey; Middle East Technical University (METU), Graduate Department of Micro and Nanotechnology, Ankara 06800, Turkey; Middle East Technical University (METU), Department of Chemistry, Ankara 06800, Turkey. Electronic address:

Poly(ε-caprolactone) (PCL) is one of the most commonly used polymers in the production of tissue engineered scaffolds for hard tissue treatments. Incorporation of cells into these scaffolds significantly enhances the healing rate of the tissue. In this study, PCL scaffolds were prepared by wet spinning technique and modified by addition of fibrinogen in order to form a fibrin network between the PCL fibers. Read More

View Article
December 2018
1 Read

Influence of arabic gum on in vitro starch digestibility and noodle-making quality of Segoami.

Int J Biol Macromol 2018 Dec 3. Epub 2018 Dec 3.

Department of Food and Nutrition, Hanyang University, Seoul, 04763, Republic of Korea. Electronic address:

The effects of arabic gum on the quality attributes of rice noodles were characterized in terms of physical properties as well as in vitro starch digestibility. Segoami (high amylose rice) was used to develop rice noodle with low predicted glycemic index (pGI). First, the processing condition for Segoami noodle was investigated at different levels of water content (100%-175%) and steaming time (1-5 min). Read More

View Article
December 2018
1 Read

Structural characterization, teratogenicity and in vitro avian antimicrobial activity of posterior salivary gland (PSG) toxin from cuttlefish, Sepia prashadi.

Int J Biol Macromol 2018 Dec 3. Epub 2018 Dec 3.

Native Medicine and Marine Pharmacology Laboratory, Faculty of Allied Health Sciences, Chettinad Academy of Research and Education, Kelambakkam, Chennai 603 103, Tamil Nadu, India. Electronic address:

A low molecular weight posterior salivary gland (PSG) toxin was isolated and purified from the cuttlefish Sepia prashadi by Reverse Phase High Performance Liquid Chromatography (RP-HPLC). The protein and neutral sugar content of the PSG toxin was determined to be 1.033 mg/g and 282 μg/g. Read More

View Article
December 2018

Preparation of thin-film electrolyte from chitosan-containing ionic liquid for application to electric double-layer capacitors.

Int J Biol Macromol 2018 Dec 3. Epub 2018 Dec 3.

Faculty of Chemistry, Materials and Bioengineering, Kansai University, Osaka 564-8680, Japan. Electronic address:

A novel thin-film electrolyte (TFE) based on chitosan (CS) with 1‑ethyl‑3‑methylimidazolium tetrafluoroborate (EMImBF) was prepared by a new procedure for use as a solid electrolyte in electric double-layer capacitors (EDLCs). In this system, EMImBF plays important roles as both a dissolving solution and a charge carrier for EDLC application. By analyzing and characterizing the obtained products, the CS-TFEs showed a surface without CS/EMImBF phase separation and with high thermal stability and good tensile properties. Read More

View Article
December 2018
1 Read

The novel cationic cell-penetrating peptide PEP-NJSM is highly active against Staphylococcus epidermidis biofilm.

Int J Biol Macromol 2018 Dec 3. Epub 2018 Dec 3.

Laboratory of Molecular and Cellular Screening Processes, Centre of Biotechnology of Sfax, University of Sfax, Road Sidi Mansour km 6, PO BOX 1177, 3018 Sfax, Tunisia.

A cationic cell-penetrating peptide PEP-NJSM was identified in human virus proteomes by a screening of charge clusters in protein sequences generating cell penetrating peptides (CPP). PEP-NJSM was selectively active against Gram positive Staphylococcus epidermidis as antibacterial agent with MIC value of 128 μM compared to the Gram-negative Pseudomonas aeruginosa strain with MIC value exceeded 512 μM. The selected peptide exhibited an important anti-biofilm activity even at sub-MIC levels. Read More

View Article
December 2018
1 Read

Glucuronorhamnoxylan from Capsosiphon fulvescens inhibits the growth of HT-29 human colon cancer cells in vitro and in vivo via induction of apoptotic cell death.

Int J Biol Macromol 2018 Dec 3. Epub 2018 Dec 3.

Department of Biotechnology, The Catholic University of Korea, Bucheon, Gyeonggi-do 14662, Republic of Korea. Electronic address:

Colorectal cancer is the third most diagnosed cancer and a leading cause of cancer death. Dissatisfaction with currently available anti-colorectal cancer drugs caused by unwanted side effects and low efficacy necessitates new therapeutic agents. In the present study, a sulfated glucuronorhamnoxylan polysaccharide (named SPS-CF) purified from a green alga Capsosiphon fulvescens was evaluated for its anti-cancer activity in vitro and in vivo against colorectal cancer. Read More

View Article
December 2018

Violence and aggression in young women: The importance of psychopathy and neurobiological function.

Physiol Behav 2018 Dec 3. Epub 2018 Dec 3.

Institute for Drug and Alcohol Studies, Departments of Psychiatry, Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA 23298, United States.

Psychopathy is one of the most researched risk factors for violence. Yet, research in women is sparse. The present study aimed to test if the link between the four-facet structure of psychopathy and interpersonal violence and aggression was moderated by neurobiological function (indexed by resting respiratory sinus arrhythmia; RSA). Read More

View Article
December 2018

Anticancer activity modulation of an innovative solid formulation of extra virgin olive oil by cultured zeolite scaffolds.

Food Chem Toxicol 2018 Dec 3. Epub 2018 Dec 3.

Research Institute on Membrane Technology, Unit of Zeolite Membranes, ITM-CNR, University of Calabria, Cubo 17/c, 87036, Rende, Italy.

This paper deals with the design and manufacture of pure and hybrid synthetic (Mixed Matrix Membranes, MMMs) zeolite scaffolds (containing various amount of zeolite crystals dispersed in a polymeric matrix) to obtain new biomaterials. These scaffolds can potentially be used in the field of translational medicine to obtain innovative results to address tumorigenesis mechanisms with the promotion of an effort to deal with technical methods and information. Since olive oil has beneficial effects in healthy human cells and slows down and/or inhibits cell growth, the aim of this work was to monitor the protective and beneficial antitumor effects of olive oil in a new solid formulation (Spread Bio-Oil) on cancer cell cultured on zeolite scaffolds. Read More

View Article
December 2018

Optimal control applied to a temperature dependent schistosomiasis model.

Biosystems 2018 Dec 3. Epub 2018 Dec 3.

School of Life Sciences, College of Agriculture, Engineering and Science, Westville Campus, University of KwaZulu-Natal, Durban, South Africa.

Schistosomiasis, the most common water-borne infection worldwide, continues to pose a serious public health challenge in developing nations and to travellers who visit these endemic regions. We apply optimal control on a temperature dependent schistosomiasis model. Our optimal control aims to minimize the pre-patent and patent human population at minimal costs. Read More

View Article
December 2018
1 Read

An Interactive and Low-Cost Full Body Rehabilitation Framework Based on 3D Immersive Serious Games.

J Biomed Inform 2018 Dec 3. Epub 2018 Dec 3.

Department of Computer Science Sapienza University of Rome, Via Salaria 113, 00198, Rome, Italy. Electronic address:

Strokes, surgeries, or degenerative diseases can impair motor abilities and balance. Long-term rehabilitation is often the only way to recover, as completely as possible, these lost skills. To be effective, this type of rehabilitation should follow three main rules. Read More

View Article
December 2018
1 Read

Soluble mannose receptor levels in blood correlate to disease severity in patients with community-acquired pneumonia.

Immunol Lett 2018 Dec 3. Epub 2018 Dec 3.

Department of R&D, Hycult Biotechnology, Uden, the Netherlands. Electronic address:

Purpose: Community-acquired pneumonia (CAP) is the most common form of pneumonia and is a leading infectious cause worldwide. Identification of patients that are at risk to develop severe disease has proven to be a major challenge. Soluble mannose receptor (sMR; sCD206) is a new serum marker for macrophage activation. Read More

View Article
December 2018
2 Reads

Bisphenol F causes disruption of gonadotropin-releasing hormone neural development in zebrafish via an estrogenic mechanism.

Neurotoxicology 2018 Dec 3. Epub 2018 Dec 3.

Department of Biology, Neuroscience Program, University of Puget Sound, Tacoma, Washington, USA. Electronic address:

Gonadotropin releasing hormone (GnRH) neurons in the brain are the main controllers of reproduction and reproductive behavior in most vertebrates, and are susceptible to endocrine disruption by different bisphenols. While the endocrine disrupting properties of bisphenol A have been well documented, commonly used analogues such as bisphenol F (BPF) are not as well studied. In this study we examined the effects of early, low-dose, chronic BPF exposure on the development of the GnRH neural system in the zebrafish embryo. Read More

View Article
December 2018

Regulation of Human Hsc70 ATPase and Chaperone Activities by Apg2: Role of the Acidic Subdomain.

J Mol Biol 2018 Dec 3. Epub 2018 Dec 3.

Instituto Biofisika (UPV/EHU, CSIC) y Dpto. de Bioquímica y Biología Molecular, Facultad de Ciencia y Tecnología, Universidad del País Vasco, Barrio Sarriena S/N, 48490, Leioa, Spain. Electronic address:

Protein aggregate reactivation in metazoans is accomplished by the combined activity of Hsp70, Hsp40 and Hsp110 chaperones. Hsp110s support the refolding of aggregated polypeptides acting as specialized nucleotide exchange factors of Hsp70. We have studied how Apg2, one of the three human Hsp110s, regulates the activity of Hsc70 (HspA8), the constitutive Hsp70 in our cells. Read More

View Article
December 2018

A diagnostic study comparing conventional and real-time PCR for Strongyloides stercoralis on urine and on faecal samples.

Acta Trop 2018 Dec 3. Epub 2018 Dec 3.

Centre for Tropical Diseases, IRCCS Sacro Cuore Don Calabria Hospital, Negrar 37024, Italy.

Strongyloides stercoralis is a soil-transmitted helminth with a wide distribution in tropical and subtropical areas. The diagnosis of S. stercoralisinfection can be challenging, due to the low sensitivity of microscopic examination of stool samples and coproculture. Read More

View Article
December 2018
  • Page 1 of 43350