1,672 results match your criteria Low Back Pain and Sciatica


The utility of diagnostic selective nerve root blocks in the management of patients with lumbar radiculopathy: a systematic review.

BMJ Open 2019 Apr 20;9(4):e025790. Epub 2019 Apr 20.

Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

Objective: Lumbar radiculopathy (LR) often manifests as pain in the lower back radiating into one leg (sciatica). Unsuccessful back surgery is associated with significant healthcare costs and risks to patients. This review aims to examine the diagnostic accuracy of selective nerve root blocks (SNRBs) to identify patients most likely to benefit from lumbar decompression surgery. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-025790DOI Listing

Normalization of Spinal Cord Displacement with the Straight leg Raise and Resolution of Sciatica in Patients with Lumbar Intervertebral Disc Herniation: A 1.5-Year Follow-up Study.

Spine (Phila Pa 1976) 2019 Mar 26. Epub 2019 Mar 26.

Department of Physical and Rehabilitation Medicine, Kuopio University Hospital, Kuopio.

Study Design: Controlled radiologic follow-up study.

Objective: To ascertain if changes in cord excursion with SLR at 1.5-year follow-up time accompany changes in clinical symptoms SUMMARY OF BACKGROUND DATA. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003047DOI Listing
March 2019
1 Read

Parallels between lumbosacral radiculopathy and complex regional pain syndrome: α1-adrenoceptor upregulation, reduced dermal nerve fibre density and hemi-sensory disturbances in post-surgical sciatica.

Pain 2019 Apr 2. Epub 2019 Apr 2.

College of Science, Health, Engineering and Education, Murdoch University, Perth, Western Australia.

Residual lower limb pain after low back surgery (post-surgical sciatica) and complex regional pain syndrome involving a lower limb (CRPS) are separate conditions, but may share some mechanisms (e.g., tissue inflammation, neuro-immune disturbances and central neuro-plasticity). Read More

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http://dx.doi.org/10.1097/j.pain.0000000000001574DOI Listing
April 2019
1 Read

Responsiveness of the modified lower extremity functional scale in patients with low back pain and sciatica: A comparison with pain intensity and the modified Roland-Morris Disability Scale.

Medicine (Baltimore) 2019 Apr;98(14):e15105

Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan, ROC.

We tested the responsiveness of the modified Lower Extremity Functional Scale (LEFS) for patients with low back pain (LBP) and sciatica and made a comparison with the modified Roland-Morris Disability Scale for sciatica (RMS-L) and self-reported pain intensity measured by visual analogue scale (VAS).One hundred and forty-eight participants were recruited from 2 university hospitals. The evaluation included demographic data, LBP history, and the modified LEFS, RMS-L, and VAS, with a follow-up one month later. Read More

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http://dx.doi.org/10.1097/MD.0000000000015105DOI Listing
April 2019
2 Reads

Systematic Review of Decision Analytic Modelling in Economic Evaluations of Low Back Pain and Sciatica.

Appl Health Econ Health Policy 2019 Apr 3. Epub 2019 Apr 3.

Arthritis Research UK Primary Care Centre, Research Institute for Primary Care and Health Sciences, Keele University, Staffordshire, UK.

Background: Low back pain (LBP) and sciatica place significant burden on individuals and healthcare systems, with societal costs alone likely to be in excess of £15 billion. Two recent systematic reviews for LBP and sciatica identified a shortage of modelling studies in both conditions.

Objectives: The aim of this systematic review was to document existing model-based economic evaluations for the treatment and management of both conditions; critically appraise current modelling techniques, analytical methods, data inputs, and structure, using narrative synthesis; and identify unresolved methodological problems and gaps in the literature. Read More

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http://dx.doi.org/10.1007/s40258-019-00471-wDOI Listing
April 2019
4 Reads

Benefits and harms of spinal manipulative therapy for the treatment of chronic low back pain: systematic review and meta-analysis of randomised controlled trials.

BMJ 2019 Mar 13;364:l689. Epub 2019 Mar 13.

Department of Health Sciences, Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1085, 1081HV Amsterdam, Netherlands.

Objective: To assess the benefits and harms of spinal manipulative therapy (SMT) for the treatment of chronic low back pain.

Design: Systematic review and meta-analysis of randomised controlled trials.

Data Sources: Medline, PubMed, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), CINAHL, Physiotherapy Evidence Database (PEDro), Index to Chiropractic Literature, and trial registries up to 4 May 2018, including reference lists of eligible trials and related reviews. Read More

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http://dx.doi.org/10.1136/bmj.l689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396088PMC

[Spine injections in athletes].

Sportverletz Sportschaden 2019 Feb 27. Epub 2019 Feb 27.

SRH-Gesundheitszentrum Bad Herrenalb.

A major proportion of athletes have intermittent acute low back pain at some stage of their sport life. Some athletes develop chronic low back pain, which may be a major source of failing in sports. Facet, epidural and intradiscal steroid injections for specific pain generators in the spine show different short- and long-term results. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/a-0751-0583
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http://dx.doi.org/10.1055/a-0751-0583DOI Listing
February 2019
5 Reads

Anatomic Study of the Superior Cluneal Nerve and Its Related Groove on the Iliac Crest.

World Neurosurg 2019 Feb 11. Epub 2019 Feb 11.

Seattle Science Foundation, Seattle, Washington, USA; Department of Anatomical Sciences, St. George's University, Grenada, West Indies.

Objective: Superior cluneal nerve entrapment neuropathy is one cause of low back pain often referred to as "pseudo sciatica." Studies have found that the superior cluneal nerve can arise variably from T11 to L5. The osteofibrous tunnels formed by a groove on the iliac crest might compress the superior cluneal nerve. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.210DOI Listing
February 2019
1 Read

A systematic comparative outcome analysis of surgical versus percutaneous techniques in the management of symptomatic sacral perineural (Tarlov) cysts: a meta-analysis.

J Neurosurg Spine 2019 Feb 8:1-12. Epub 2019 Feb 8.

OBJECTIVESymptomatic perineural or Tarlov cysts (TCs) are a rare cause of chronic low-back pain. Given the rarity of the disease, there is no literature consensus regarding the optimal management of these cysts.METHODSThe authors conducted a systematic comparative outcome analysis of symptomatic TCs treated with surgery (group A, 32 studies, n = 333) or percutaneous interventions (group B, 6 studies, n = 417) analyzing the demographic characteristics, baseline characteristics of the cysts, clinical presentations, types of interventions, complication rates, and the recurrence rate in both treatment groups. Read More

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http://dx.doi.org/10.3171/2018.10.SPINE18952DOI Listing
February 2019
2 Reads

Neuromuscular morphometric characteristics in low back pain with unilateral radiculopathy caused by disc herniation: An ultrasound imaging evaluation.

Musculoskelet Sci Pract 2019 04 1;40:80-86. Epub 2019 Feb 1.

Department of Mental Health, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway. Electronic address:

Background: Little is known about the neuromuscular morphometric characteristics in patients with sciatica.

Objective: To evaluate the possible changes of nerve and muscle structures in patients with low back pain with unilateral radiculopathy due to lumbar disc herniation by ultrasound imaging.

Design: A case-control observational study. Read More

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http://dx.doi.org/10.1016/j.msksp.2019.01.016DOI Listing
April 2019
6 Reads

Pregabalin for neuropathic pain in adults.

Cochrane Database Syst Rev 2019 01 23;1:CD007076. Epub 2019 Jan 23.

Pain Research and Nuffield Department of Clinical Neurosciences (Nuffield Division of Anaesthetics), University of Oxford, Pain Research Unit, Churchill Hospital, Oxford, Oxfordshire, UK, OX3 7LE.

Background: This review updates part of an earlier Cochrane Review titled "Pregabalin for acute and chronic pain in adults", and considers only neuropathic pain (pain from damage to nervous tissue). Antiepileptic drugs have long been used in pain management. Pregabalin is an antiepileptic drug used in management of chronic pain conditions. Read More

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http://dx.doi.org/10.1002/14651858.CD007076.pub3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353204PMC
January 2019
11 Reads

Foraminoplasty at the Tip or Base of the Superior Articular Process for Lateral Recess Stenosis in Percutaneous Endoscopic Lumbar Discectomy: A Multicenter, Retrospective, Controlled Study with 2-Year Follow-Up.

Biomed Res Int 2018 19;2018:7692794. Epub 2018 Dec 19.

Department of Orthopaedics, The Second Affiliated Hospital, Chongqing Medical University, No. 76 Linjiang Road, District Yuzhong, Chongqing, China.

Objective: To compare the clinical efficacy and complications which obtained foraminoplasty at the tip or base of the superior articular process (SAP) for the patients with lateral recess stenosis treated by percutaneous endoscopic lumbar discectomy (PELD).

Methods: Between January 2015 and January 2016, 156 patients of lumbar disc herniation accompanying with lateral recess stenosis were treated with PELD in five tertiary hospitals and fulfilled the 2-year follow-up. Among them, 78 patients obtained a foraminoplasty at the tip of SAP (group A), and foraminoplasty at the base of SAP was performed in the other 78 cases (group B). Read More

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http://dx.doi.org/10.1155/2018/7692794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313963PMC
December 2018
10 Reads

Primary tuberculous psoas abscess as a postpartum complication: Case report and literature review.

Surg Neurol Int 2018 28;9:239. Epub 2018 Nov 28.

Department of Surgery, Avicenne Military Hospital of Marrakech, Mohammed V University in Rabat, Morocco.

Background: Primary psoas abscess is an unusual clinical entity rarely encountered in the postpartum period. Only seven cases have been reported to date. Here, we present a woman with a primary psoas abscess caused by and occurred 2 months following a normal vaginal birth. Read More

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http://dx.doi.org/10.4103/sni.sni_329_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287337PMC
November 2018
4 Reads

Retrolisthesis and lumbar disc herniation: a postoperative assessment of outcomes at 8-year follow-up.

Spine J 2018 Dec 27. Epub 2018 Dec 27.

Department of Orthopaedic Surgery, Maimonides Bone and Joint Center, Maimonides Medical Center, Brooklyn, NY 11201, USA.

Background Context: Lumbar disc herniation and retrolisthesis have been shown to be significant degenerative changes that can be associated with back pain. Current literature has shown evidence that retrolisthesis is associated with similar baseline function in patients with L5-S1 disc herniation, but worse postoperative outcomes 2 years after lumbar discectomy. However, literature comparing long-term postoperative outcomes at 8-year follow-up in patients with L5-S1 disc herniation with retrolisthesis is lacking. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15299430183131
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http://dx.doi.org/10.1016/j.spinee.2018.12.010DOI Listing
December 2018
15 Reads
2.426 Impact Factor

Combination Drug Therapy for the Management of Low Back Pain and Sciatica: Systematic Review and Meta-Analysis.

J Pain 2019 01 3;20(1):1-15. Epub 2018 Jul 3.

Sydney School of Public Health, University of Sydney and Institute for Musculoskeletal Health, Sydney, Australia.

Combining medicines may give greater pain relief and/or improved tolerability. We conducted a systematic review to investigate the effects of combination drug therapy in patients with low back pain and/or sciatica on pain, disability, and adverse events. Databases and trial registers were searched from inception to July 27, 2017, for randomized trials of (sub)acute or chronic back pain or sciatica participants that were administered combination drug therapy compared with monotherapy or placebo. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15265900183031
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http://dx.doi.org/10.1016/j.jpain.2018.06.005DOI Listing
January 2019
8 Reads

Biologic Drugs as Analgesics for the Management of Low Back Pain and Sciatica.

Pain Med 2018 Dec 20. Epub 2018 Dec 20.

Liverpool Reviews and Implementation Group, University of Liverpool, Liverpool, UK.

Objective: To discuss the current knowledge on the impact of commonly used biologic agents (i.e., anti-tumor necrosis factor-alpha [anti-TNF-α] and anti-nerve growth factor [anti-NGF]) in the management of low back pain with or without sciatica. Read More

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https://academic.oup.com/painmedicine/advance-article/doi/10
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http://dx.doi.org/10.1093/pm/pny214DOI Listing
December 2018
5 Reads

Minimally invasive transforaminal lumbar interbody fusion for dual-segment lower lumbar degenerative disease.

Wideochir Inne Tech Maloinwazyjne 2018 Dec 1;13(4):525-532. Epub 2018 Jun 1.

Department of Orthopedics, Taizhou Hospital, Zhejiang, China.

Introduction: Transforaminal lumbar interbody fusion (TLIF) has been widely used to treat degenerative lumbar diseases. The PIPELINE Access minimally invasive system allows reduction of the trauma to the patient during TLIF.

Aim: To present our preliminary experience with the minimally invasive TLIF (mTLIF) technique performed on the first 7 patients with dual-segment lower lumbar degenerative disease (DS-LLDD). Read More

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http://dx.doi.org/10.5114/wiitm.2018.76151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280081PMC
December 2018
4 Reads

PEEK versus metal cages in posterior lumbar interbody fusion: a clinical and radiological comparative study.

Musculoskelet Surg 2018 Dec 10. Epub 2018 Dec 10.

S.C. Ortopedia e Traumatologia, IRCCS Policlinico San Matteo, Università degli Studi di Pavia, Viale Camillo Golgi 19, 27100, Pavia, PV, Italy.

Background: Low back pain and sciatica represent a common disabling condition with a significant impact on the social, working and economic lives of patients. Transforaminal lumbar interbody fusion (TLIF) is a surgical procedure used in degenerative spine conditions. Several types of cages were used in the TLIF procedure. Read More

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http://dx.doi.org/10.1007/s12306-018-0580-6DOI Listing
December 2018
1 Read

'Life on hold': The lived experience of radicular symptoms. A qualitative, interpretative inquiry.

Musculoskelet Sci Pract 2019 02 23;39:51-57. Epub 2018 Nov 23.

School of Health Sciences, University of Southampton, Highfield, Southampton, SO17 1BJ, UK. Electronic address:

Background: Patients with radicular symptoms can experience high levels of pain and disability with at least a third experiencing on-going symptoms 12 months after onset.

Aims: To explore 'what matters' about living with radicular symptoms at the point of seeing a spinal specialist and to consider how care can be aligned to best address need.

Methods: In this qualitative study, based on the principles of interpretative phenomenological analysis, 14 participants with a clinical presentation of radicular symptoms were purposively recruited from an NHS, Musculoskeletal Service in the UK. Read More

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http://dx.doi.org/10.1016/j.msksp.2018.11.005DOI Listing
February 2019
4 Reads

[Spinal Injections, Epidural Neurolysis and Denervation for Specific Low Back Pain and Sciatica].

Z Orthop Unfall 2018 Nov 27. Epub 2018 Nov 27.

Department Wirbelsäule, Sportklinik Stuttgart GmbH.

Background: Many members of the adult population suffer acute low back pain at some stage in life. A specific cause is found in only a rather small number of these patients. Some of the patients develop chronic low back pain and this is a major source of disability. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/a-0767-7428
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http://dx.doi.org/10.1055/a-0767-7428DOI Listing
November 2018
13 Reads

Percutaneous Total Endoscopic Resection of Partial Articular Processes for Treatment of Lateral Crypt Stenosis and Lumbar Spinal Stenosis: Technical Report and Efficacy Analysis.

Biomed Res Int 2018 18;2018:9130182. Epub 2018 Oct 18.

Department of Spinal Surgery, The First Affiliated Hospital of Zunyi Medical College, Zunyi 563000, China.

Objective: To observe the clinical curative effect of posterior total endoscopic precision decompression for the treatment of single-segment lateral crypt lumbar spinal stenosis (LSS).

Method: A total of 27 patients with single-segment LSS satisfying the inclusion criteria were recruited from July 2013 to September 2015. There were 18 cases of unilateral stenosis of the L segments and 9 cases of unilateral stenosis of the L-S segment. Read More

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http://dx.doi.org/10.1155/2018/9130182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211200PMC
February 2019

[Diagnosis and interventional treatment of pain syndromes after surgery for degenerative lumbar spine diseases].

Zh Vopr Neirokhir Im N N Burdenko 2018;82(5):55-61

Nikiforov All-Russian Center of Emergency and Radiation Medicine, St. Petersburg, Russia.

Postoperative pain accompanies up to 20% of interventions for degenerative spine diseases (DSDs). The epidemiologic data are contradictory; clinical and radiological diagnostics is often low efficient; capabilities of interventional diagnosis and treatment techniques are poorly understood.

Purpose: The study purpose was to investigate the structure of pain syndromes after surgery for DSDs of the lumbar spine, based on complex diagnostics, as well as to evaluate the capabilities of interventional treatment. Read More

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http://dx.doi.org/10.17116/neiro20188205155DOI Listing
April 2019
12 Reads

Test-retest reliability of nerve and muscle morphometric characteristics utilizing ultrasound imaging in individuals with unilateral sciatica and controls.

Chiropr Man Therap 2018 6;26:47. Epub 2018 Nov 6.

7Department of Mental Health, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.

Background: Ultrasound imaging has been suggested for studying the structure and function of nerves and muscles; however, reliability studies are limited to support the usage. The main aim of this study was to explore the intrarater within-session reliability of evaluating the sciatic nerve and some related muscles morphology by ultrasound imaging.

Methods: Three B-mode images from two scans (transverse and longitudinal) were acquired from the multifidus, biceps femoris, soleus and medial gastrocnemius muscles bilaterally from 15 participants with sciatica and 15 controls in one session, 1-h apart. Read More

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https://chiromt.biomedcentral.com/articles/10.1186/s12998-01
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http://dx.doi.org/10.1186/s12998-018-0215-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219045PMC
November 2018
21 Reads

The majority of piriformis muscles are innervated by the superior gluteal nerve.

Clin Anat 2019 Mar 21;32(2):282-286. Epub 2018 Dec 21.

Seattle Science Foundation, Seattle, Washington.

The piriformis muscle is clinically implicated in pain disorders, posterior approaches for total hip arthroplasty, and iatrogenic injury to the muscle and the surrounding nerves. The piriformis muscle has been said to receive innervation from L5 to S3 ventral rami with most sources using S1 and S2 ventral rami as the most common innervation this muscle. However, descriptions of the nerve in the literature are vague. Read More

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http://doi.wiley.com/10.1002/ca.23311
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http://dx.doi.org/10.1002/ca.23311DOI Listing
March 2019
17 Reads

The association of high-intensity zones on MRI and low back pain: a systematic review.

Scoliosis Spinal Disord 2018 20;13:22. Epub 2018 Oct 20.

3Department of Orthopaedic Surgery, RUSH University Medical Center, 1611 W. Harrison Street, Suite 204G - Orthopaedic Surgery, Chicago, IL 60612 USA.

Background: Magnetic resonance imaging (MRI) of the lumbar spine is commonly used to identify the source of low back pain (LBP); however, its use has been questionable. Throughout the years, numerous lumbar phenotypes (e.g. Read More

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https://scoliosisjournal.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/s13013-018-0168-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195950PMC
October 2018
34 Reads

Biographical suspension and liminality of Self in accounts of severe sciatica.

Soc Sci Med 2018 Dec 2;218:28-36. Epub 2018 Oct 2.

Arthritis Research UK Primary Care Centre, Research Institute for Primary Care & Health Sciences, Keele University, Staffordshire, ST5 5BG, UK; Midlands Partnership NHS Foundation Trust, Haywood Hospital, Stoke-on-Trent, Staffordshire, ST6 7AG, UK. Electronic address:

Sciatica is a common form of low back pain (LBP) that has been identified as distinct both in terms of the persistence and severity of symptoms. Little research has explored individual experiences of sciatica, and none focuses on individuals with the most severe, long-lasting symptoms who may experience the most profound impact. This paper addresses this gap through proposing a theoretical framework for understanding such experiences, that of biographical suspension as a form of liminality of Self. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02779536183056
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http://dx.doi.org/10.1016/j.socscimed.2018.10.001DOI Listing
December 2018
15 Reads

The Use of Magnetic Resonance Imaging and Plain Radiographs Among Adolescents With Back Pain and Adolescent Idiopathic Scoliosis.

Int J Spine Surg 2018 Apr 3;12(2):154-159. Epub 2018 Aug 3.

Department of Orthopaedics, Wexner Medical Center, The Ohio State University, Columbus, Ohio.

Background: Low back pain (LBP) and adolescent idiopathic scoliosis (AIS) are common pediatric diagnoses. The workup for these diagnoses can be highly variable and can use significant health care resources. There has been no analysis to date on the use of imaging for workup of AIS and/or LBP. Read More

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http://dx.doi.org/10.14444/5023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159641PMC
April 2018
4 Reads

Factors associated with physiotherapists' preference for MRI in primary care patients with low back and leg pain.

Musculoskelet Sci Pract 2018 12 20;38:46-52. Epub 2018 Sep 20.

Arthritis Research UK Primary Care Centre, Research Institute for Primary Care & Health Sciences, Keele University, Staffordshire, ST5 5BG, UK; Haywood Rheumatology Centre, Haywood Hospital, Stoke-on-Trent, Staffordshire, ST6 7AG, UK. Electronic address:

Background: Criticisms about overuse of MRI in low back pain are well documented. Yet, with the exception of suspicion of serious pathology, little is known about factors that influence clinicians' preference for magnetic resonance imaging (MRI) at first consultation.

Objective: To explore factors associated with physiotherapists' preference for MRI for patients consulting with benign low back and leg pain (LBLP) including sciatica. Read More

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http://dx.doi.org/10.1016/j.msksp.2018.09.003DOI Listing
December 2018
17 Reads

Wallis Interspinous Spacer for Treatment of Primary Lumbar Disc Herniation: Three-Year Results of a Randomized Controlled Trial.

World Neurosurg 2018 Dec 24;120:e1331-e1336. Epub 2018 Sep 24.

Southern Medical University, Guangzhou, People's Republic of China; Department of Orthopedics, The Third Affiliated Hospital of Southern Medical University, Guangzhou, People's Republic of China. Electronic address:

Background: Limited data have been reported showing whether the second-generation Wallis interspinous spacer improves function after lumbar spine decompression or discectomy.

Methods: We evaluated Wallis interspinous spacer placement in patients with low back pain or sciatica secondary to a confirmed diagnosis of primary lumbar disc herniation. The patients were treated from July 2008 to July 2011 at 1 institution. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.09.086DOI Listing
December 2018
9 Reads

Assessment of variability in traction interventions for patients with low back pain: a systematic review.

Chiropr Man Therap 2018 17;26:35. Epub 2018 Sep 17.

4Department of Physical Therapy, School of Health and Rehabilitation Sciences, University of Pittsburgh, Bridgeside Point 1, 100 Technology Drive, Suite 210, Pittsburgh, PA 15219 USA.

Background: Previous systematic reviews have concluded that lumbar traction is not effective for patients with low back pain (LBP), yet many clinicians continue to assert its clinical effectiveness.

Objective: To systematically identify randomized controlled trials (RCTs) of traction and explore the variability of traction interventions used in each RCT.

Method: A literature search started in September 2016 to retrieve systematic reviews and individual RCTs of lumbar traction. Read More

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https://chiromt.biomedcentral.com/articles/10.1186/s12998-01
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http://dx.doi.org/10.1186/s12998-018-0205-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139896PMC
September 2018
21 Reads

Introduction to the Special Issue on Acupuncture-Basic Research and Clinical Application.

Authors:
Gerhard Litscher

Medicines (Basel) 2018 Sep 4;5(3). Epub 2018 Sep 4.

Research Unit for Complementary and Integrative Laser Medicine, Research Unit of Biomedical Engineering in Anesthesia and Intensive Care Medicine, and TCM Research Center Graz, Medical University of Graz, Auenbruggerplatz 39, EG19, 8036 Graz, Austria.

This special issue focuses on the further investigation, development, and modernization of acupuncture in basic research settings, as well as in clinical applications. The special issue contains 12 articles reporting latest evidence-based results of acupuncture research, and exploring acupuncture in general. Altogether 44 authors from all over the world contributed to this special issue. Read More

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http://dx.doi.org/10.3390/medicines5030099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164726PMC
September 2018

Lumbar disc herniation treated by microendoscopic discectomy : Prognostic predictors of long-term postoperative outcome.

Orthopade 2018 Dec;47(12):992-1000

Spine Surgery Center, Zhongda Hospital, Medical School, Southeast University, 87 Dingjiaqiao, 210009, Nanjing, Jiangsu, China.

Purpose: Microendoscopic discectomy (MED) is becoming an established and effective minimally invasive surgical method for the treatment of lumbar disc herniation (LDH); however, the absence of prognostic factors for long-term outcomes after MED results in a lack of specific criteria for appropriate patient selection. Therefore, we evaluated the long-term outcomes and associated predictors in patients who underwent MED for LDH.

Material And Methods: Baseline and follow-up data for 664 LDH patients who suffered from sciatica and underwent primary MED were reviewed retrospectively. Read More

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http://dx.doi.org/10.1007/s00132-018-3624-6DOI Listing
December 2018
3 Reads
0.660 Impact Factor

Diagnostic accuracy of diagnostic imaging for lumbar disc herniation in adults with low back pain or sciatica is unknown; a systematic review.

Chiropr Man Therap 2018 21;26:37. Epub 2018 Aug 21.

3Department of Public Health, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.

Main Text: We aim to summarize the available evidence on the diagnostic accuracy of imaging (index test) compared to surgery (reference test) for identifying lumbar disc herniation (LDH) in adult patients.For this systematic review we searched MEDLINE, EMBASE and CINAHL (June 2017) for studies that assessed the diagnostic accuracy of imaging for LDH in adult patients with low back pain and surgery as the reference standard. Two review authors independently selected studies, extracted data and assessed risk of bias. Read More

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http://dx.doi.org/10.1186/s12998-018-0207-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102824PMC
August 2018
5 Reads

The effectiveness of non-surgical treatments, re-discectomy and minimally invasive transforaminal lumbar interbody fusion in post-discectomy pain syndrome.

J Spine Surg 2018 Jun;4(2):414-422

Department of Orthopaedic Surgery, Hisar Intercontinental Hospital, Istanbul, Turkey.

Background: There have been many studies that reported various treatment options about recurrent disc herniation, recurrent sciatica, and low back pain following discectomy. However, evaluation and treatment algorithm of post-discectomy pain syndrome (PDPS) could not be standardized. The purpose of this study was to report the results of patients with PDPS who were treated with various treatment options with a minimum 2-year follow-up. Read More

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http://dx.doi.org/10.21037/jss.2018.04.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046348PMC
June 2018
2 Reads

Possible pathogenic mechanism of gluteal pain in lumbar disc hernia.

BMC Musculoskelet Disord 2018 Jul 11;19(1):214. Epub 2018 Jul 11.

Department of Orthopedic Surgery, West China Hospital, Sichuan University, No. 37, Guoxue Lane, Wainan Street, Wuhou District, Chengdu, 610041, Sichuan, China.

Recent reported results by Fang et al. published in BMC Musculoskeletal Disorders have added to the weight of evidence supporting association between gluteal pain and lumbar disc hernia. Their clinical finding shows the L4/5 level is the main level responsible for gluteal pain in lumbar disc hernia. Read More

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http://dx.doi.org/10.1186/s12891-018-2147-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042418PMC
July 2018
23 Reads

Sonoelastographic evaluation of the sciatic nerve in patients with unilateral lumbar disc herniation.

Skeletal Radiol 2019 Jan 7;48(1):129-136. Epub 2018 Jul 7.

Department of Neurosurgery, Yuksek Ihtisas State Hospital, Kirikkale, Turkey.

Objective: The aim of this study was to compare strain elastography (SE) and shear wave elastography (SWE) findings of the sciatic nerve in patients with unilateral lumbar disc herniation (LDH) and healthy control subjects.

Materials And Methods: The study group included patients with complaints of unilateral sciatica for 3-12 months, with foraminal stenosis due to one level of LDH (L4-L5 or L5-S1). An age- and gender-matched control group was formed of healthy subjects. Read More

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http://link.springer.com/10.1007/s00256-018-3020-7
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http://dx.doi.org/10.1007/s00256-018-3020-7DOI Listing
January 2019
14 Reads

Anticonvulsants in the treatment of low back pain and lumbar radicular pain: a systematic review and meta-analysis.

CMAJ 2018 Jul;190(26):E786-E793

The University of Sydney (Enke, H.A. New, C.H. New), Sydney Medical School Nepean, Kingswood, Australia; Westmead Hospital (H.A. New), Westmead, Australia; The University of Sydney (Mathieson, Latimer, Maher, Lin), Sydney School of Public Health; The University of Sydney and Concord Hospital (McLachlan), Faculty of Pharmacy and Centre for Education and Research on Ageing, Sydney, Australia.

Background: The use of anticonvulsants (e.g., gabapentin, pregabalin) to treat low back pain has increased substantially in recent years despite limited supporting evidence. Read More

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http://dx.doi.org/10.1503/cmaj.171333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028270PMC
July 2018
21 Reads

[Psychosocial risk factors for chronic back pain in the general population and in competitive sports : From theory to clinical screening-a review from the MiSpEx network].

Schmerz 2018 08;32(4):259-273

Professur für Sport- und Gesundheitssoziologie, Department für Gesundheitswissenschaften, Universität Potsdam, Potsdam, Deutschland.

Background: Lumbar back pain and the high risk of chronic complaints is not only an important health concern in the general population but also in high performance athletes. In contrast to non-athletes, there is a lack of research into psychosocial risk factors in athletes. Moreover, the development of psychosocial screening questionnaires that would be qualified to detect athletes with a high risk of chronicity is in the early stages. Read More

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http://dx.doi.org/10.1007/s00482-018-0307-5DOI Listing

Why are there no drugs indicated for sciatica, the most common chronic neuropathic syndrome of all?

Drug Discov Today 2018 11 9;23(11):1904-1909. Epub 2018 Jun 9.

Department of Anesthesiology and Perioperative Medicine, University of Rochester School of Medicine and Dentistry, 601 Elmwood Ave, Rochester, NY, USA.

This review examines the stark contrast between the successes and failures of the clinical development of analgesics for different types of chronic low back pain (CLBP) syndrome over the past three decades. Multiple drugs with differing mechanisms of action have been developed for nonspecific axial-predominant low back syndromes and yet not a single therapy is indicated for any neuropathic low back pain syndrome (e.g. Read More

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http://dx.doi.org/10.1016/j.drudis.2018.06.004DOI Listing
November 2018
1 Read

Exposure to whole-body vibration and hospitalization due to lumbar disc herniation.

Int Arch Occup Environ Health 2018 08 31;91(6):689-694. Epub 2018 May 31.

Department of Public Health and Clinical Medicine, Occupational and Environmental Medicine, Umeå University, 901 87, Umeå, Sweden.

Objective: The aim was to examine if exposure to whole-body vibration (WBV) increases the risk for hospitalization due to lumbar disc herniation.

Methods: The study basis is a cohort of 288,926 Swedish construction workers who participated in a national occupational health surveillance programme from 1971 until 1992. Job title, smoking habits, body weight, height and age were registered at the examinations. Read More

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http://dx.doi.org/10.1007/s00420-018-1316-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060752PMC
August 2018
4 Reads

Bed Rest for Sciatica: A Closer Look at the Evidence.

J Orthop Sports Phys Ther 2018 Jun;48(6):436-438

When managing acute nonspecific low back pain (LBP), bed rest is commonly discouraged as a form of therapy. However, when the picture includes radiating leg pain arising from the lumbar spine, the evidence is less robust. In this Viewpoint, the authors explore evidence pertaining to sciatica, defined as "low back pain with verified neurological deficits," and bed rest as part of the management of radiating leg pain. Read More

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http://dx.doi.org/10.2519/jospt.2018.0609DOI Listing
June 2018
23 Reads

Risk factors for low back pain and sciatica: an umbrella review.

Spine J 2018 09 21;18(9):1715-1721. Epub 2018 May 21.

Institute of Bone and Joint Research, The Kolling Institute, Sydney Medical School, Sydney, PO Box 4191, Pacific Hwy, NSW 2065, Australia.

Background: Low back pain (LBP) is a highly prevalent condition and it is associated with significant disability and work absenteeism worldwide. A variety of environmental and individual characteristics have been reported to increase the risk of LBP. To our knowledge, there has been no previous attempt to summarize the evidence from existing systematic reviews of risk factors for LBP or sciatica. Read More

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http://dx.doi.org/10.1016/j.spinee.2018.05.018DOI Listing
September 2018
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Top 20 Research Studies of 2017 for Primary Care Physicians.

Am Fam Physician 2018 May;97(9):581-588

McGill University, Montreal, Quebec, Canada.

Based on systematic surveillance of more than 110 medical journals, 247 studies met criteria as POEMs (patient-oriented evidence that matters) in 2017. Members of the Canadian Medical Association identified 20 of these POEMs as most relevant to practice. This article reviews the clinical questions and bottom-line answers from these studies. Read More

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May 2018
5 Reads

Effectiveness of three interventions for secondary prevention of low back pain in the occupational health setting - a randomised controlled trial with a natural course control.

BMC Public Health 2018 05 8;18(1):598. Epub 2018 May 8.

Evalua International, Espoo, Finland.

Background: We assessed the effectiveness of three interventions that were aimed to reduce non-acute low back pain (LBP) related symptoms in the occupational health setting.

Methods: Based on a survey (n = 2480; response rate 71%) on LBP, we selected a cohort of 193 employees who reported moderate LBP (Visual Analogue Scale VAS > 34 mm) and fulfilled at least one of the following criteria during the past 12 months: sciatica, recurrence of LBP ≥ 2 times, LBP ≥ 2 weeks, or previous sickness absence. A random sample was extracted from the cohort as a control group (Control, n = 50), representing the natural course of LBP. Read More

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https://bmcpublichealth.biomedcentral.com/articles/10.1186/s
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http://dx.doi.org/10.1186/s12889-018-5476-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941604PMC
May 2018
3 Reads

Noninvasive Measurement of Sciatic Nerve Stiffness in Patients With Chronic Low Back Related Leg Pain Using Shear Wave Elastography.

J Ultrasound Med 2019 Jan 6;38(1):157-164. Epub 2018 May 6.

Universidade de Lisboa, Faculdade de Motricidade Humana, Lisbon, Portugal.

Objectives: The purpose of this study was to determine whether sciatic nerve stiffness is altered in people with chronic low back-related leg pain by using shear wave elastography.

Methods: In this cross-sectional study, the sciatic nerve shear wave velocity (ie, an index of stiffness) was measured in both legs of 16 participants (8 with unilateral low back-related leg pain and 8 healthy controls). Sciatic stiffness was measured during a passive ankle dorsiflexion motion performed at 2°/s in an isokinetic dynamometer. Read More

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http://dx.doi.org/10.1002/jum.14679DOI Listing
January 2019
1 Read

Use of Multiple Data Sources for Surveillance of Work-Related Chronic Low-Back Pain and Disc-Related Sciatica in a French Region.

Ann Work Expo Health 2018 May;62(5):530-546

Univ Angers, CHU Angers, Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S, Angers, France.

Objectives: To compare the data of the French workers' compensation system (WCS) and three surveillance networks, and to determine the possibility of identifying the industry sectors most in need of programs for prevention of low-back pain (LBP).

Methods: This study compared four databases and two types of indicators in a west central region of France: • surveillance of musculoskeletal symptoms in the working population [LBP and disc-related sciatica (DRS) indicators; Cosali study] • surveillance of uncompensated work-related diseases (LBP and DRS indicators) • surveillance of lumbar disc surgery (LDS) in the general population (DRS indicator) • French WCS (disc herniation with radiculopathy caused by vibration or handling of materials; DRS indicator) People aged 20-59 were studied. The prevention index (PI) was used to rank industry sectors according to the number of cases and the prevalence/incidence rate. Read More

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http://dx.doi.org/10.1093/annweh/wxy023DOI Listing
May 2018
6 Reads

[Successful Antibiotic Treatment of Lumbar Pain].

Praxis (Bern 1994) 2018 Apr;107(9-10):535-544

1 Medbase St. Gallen, Am Vadianplatz, St. Gallen.

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http://dx.doi.org/10.1024/1661-8157/a002965DOI Listing
April 2018
5 Reads

Early onset of disc degeneration in SM/J mice is associated with changes in ion transport systems and fibrotic events.

Matrix Biol 2018 09 9;70:123-139. Epub 2018 Apr 9.

School of Biomedical Sciences, The University of Hong Kong, Pokfulam, Hong Kong SAR, China; The University of Hong Kong - Shenzhen Institute of Research and Innovation (HKU-SIRI), Hi-Tech Industrial Park, Nanshan, Shenzhen, China. Electronic address:

Intervertebral disc degeneration (IDD) causes back pain and sciatica, affecting quality of life and resulting in high economic/social burden. The etiology of IDD is not well understood. Along with aging and environmental factors, genetic factors also influence the onset, progression and severity of IDD. Read More

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http://dx.doi.org/10.1016/j.matbio.2018.03.024DOI Listing
September 2018
13 Reads

Sensitivity and Specificity of Modified Bragard Test in Patients With Lumbosacral Radiculopathy Using Electrodiagnosis as a Reference Standard.

J Chiropr Med 2018 Mar 12;17(1):36-43. Epub 2018 Jan 12.

Department of Physical Medicine and Rehabilitation, Shiraz University of Medical Sciences, Shiraz, Fars, Islamic Republic of Iran.

Objective: The purpose of this study was to assess the diagnostic accuracy of a modified Bragard test compared with the straight leg raise (SLR) test in patients presenting with electrodiagnostic evidence of L5 and S1 nerve root compression.

Methods: This was a cross-sectional study conducted on 506 consecutive patients with signs and symptoms consistent with lumbosacral radiculopathy confirmed by electrodiagnostic study. Patients were evaluated from September 2013 to September 2015 in the physical medicine and rehabilitation outpatient clinic of Shahid Faghihi Teaching Hospital, Shiraz, Iran. Read More

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http://dx.doi.org/10.1016/j.jcm.2017.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883635PMC
March 2018
8 Reads