18,891 results match your criteria Loose Anagen Syndrome


New cell lines for efficient propagation of koi herpesvirus and infectious salmon anaemia virus.

J Fish Dis 2018 Dec 10. Epub 2018 Dec 10.

Friedrich-Loeffler-Institut (FLI), Institute of Infectology, Greifswald-Insel Riems, Germany.

The production of piscine viruses, in particular of koi herpesvirus (KHV, CyHV-3) and infectious salmon anaemia virus (ISAV), is still challenging due to the limited susceptibility of available cell lines to these viruses. A number of cell lines from different fish species were compared to standard diagnostic cell lines for KHV and ISAV regarding their capability to exhibit a cytopathic effect (CPE) and to accumulate virus. Two cell lines, so far undescribed, appeared to be useful for diagnostic purposes. Read More

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December 2018

Multimodal ultrasonographic evaluation in a case with unossified primary synovial osteochondromatosis.

Med Ultrason 2018 Dec;20(4):527-530

2nd Internal Medicine Department, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.

Primary synovial osteochondromatosis is a rare disorder and its diagnosis remains a challenge to the physician. We present the case of 36 year old patient with right knee monoarthritis in which ultrasound findings, corroborated with clinical and histopathological evidence confirmed the diagnosis of unossified primary synovial osteochondromatosis. The arthroscopy with synovectomy found multiple intra-articular loose bodies occupying the entire joint. Read More

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December 2018

The Tutankhamun Technique in Hip Arthroscopy.

Arthrosc Tech 2018 Nov 15;7(11):e1167-e1171. Epub 2018 Oct 15.

Laredo Arthroscopy Center, Laredo, Texas, U.S.A.

Hip arthroscopy has been increasing tremendously in the past decade and is a very common surgical procedure to repair femoroacetabular impingement. To access the hip joint, distraction is mandatory to treat intra-articular disorders such as labral tears, cartilage loose bodies, and ligamentum teres tears and to evaluate the condition of the femoral head and acetabular cartilage. To distract the hip, counterdistraction is needed, and this is achieved with placement of a bulky and cushioned perineal post. Read More

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November 2018

Concomitant Arthroscopy With Labral Reconstruction and Periacetabular Osteotomy for Hip Dysplasia.

Arthrosc Tech 2018 Nov 15;7(11):e1141-e1147. Epub 2018 Oct 15.

American Hip Institute, Westmont, Illinois, U.S.A.

In the setting of true hip dysplasia, the high prevalence of intra-articular pathology may lead to recurrent symptoms and failure after periacetabular osteotomy (PAO). Femoral neck osteochondroplasty, microfracture, removal of loose bodies, and labral repair are examples of procedures that are performed with concomitant arthroscopy. When damage to the labrum is too severe to repair, reconstruction instead of extensive debridement before PAO can be more effective in restoring the labral seal to maintain joint lubrication and chondral protection. Read More

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November 2018

Graft rejection-like reactions in the early postoperative period after deep anterior lamellar keratoplasty for keratoconus: a retrospective study.

Clin Ophthalmol 2018 14;12:2315-2322. Epub 2018 Nov 14.

Department of Ophthalmology, Japan Community Health Care Organization Hoshigaoka Medical Center, Hirakata, Osaka 573-8511, Japan.

Background: Deep anterior lamellar keratoplasty (DALK) is indicated to correct high astigmatism in patients with keratoconus (KC) and no evidence of Descemet's membrane rupture. However, some patients with KC experience graft rejection-like inflammatory reactions within 2 months (usually in the first week) after DALK. The aim of this study was to identify the characteristics and influencing factors of these reactions by reviewing the records of patients who underwent DALK or penetrating keratoplasty (PKP) for KC or other corneal problems. Read More

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November 2018

Reconstruction of anterior chest wall: a clinical analysis.

J Cardiothorac Surg 2018 Dec 7;13(1):124. Epub 2018 Dec 7.

Department of thoracic surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, China.

Objective: To investigate the methods and clinical efficacy of reconstruction of chest defects with titanium sternal fixation system after the surgical resection of sternal tumors.

Methods: A total of 6 patients with sternal tumor who were diagnosed and underwent resection and repair of the chest wall defects by titanium plates system, from 2017.3 to 2017. Read More

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December 2018
1 Read

The Yale Center for Biomedical Innovation and Technology (CBIT): One Model to Accelerate Impact From Academic Health Care Innovation.

Acad Med 2018 Dec 4. Epub 2018 Dec 4.

A.L. Siefert is engineering director, Yale Center for Biomedical Innovation and Technology (CBIT), and biomedical engineering lecturer, Yale University, New Haven, Connecticut. M.S. Cartiera is investment and innovation director, Yale CBIT and Center for Health Innovation, Yale New Haven Health System, New Haven, Connecticut. A.N. Khalid is clinical director, Yale CBIT, New Haven, Connecticut; and clinical instructor, Harvard Medical School, Boston, Massachusetts. M.C. Nantel is program coordinator, Yale CBIT, New Haven, Connecticut. C.R. Loose is co-executive director, Yale CBIT, New Haven, Connecticut; and chief scientific officer, Frequency Therapeutics, Cambridge, Massachusetts. P.G. Schulam is co-founder, Yale CBIT, chair of Urology, Yale School of Medicine, and faculty director, Tsai Center for Innovative Thinking, Yale University, New Haven, Connecticut. W.M. Saltzman is co-founder, Yale CBIT, and Goizueta Foundation Professor of biomedical and chemical engineering, Yale University, New Haven, Connecticut. M.K. Dempsey is co-executive director, Yale CBIT, New Haven, Connecticut; and entrepreneur-in-residence, Consortia for Improving Medicine with Innovation & Technology (CIMIT), Boston, Massachusetts.

The process of translating academic biomedical advances into clinical care improvements is difficult, risky, expensive, and poorly understood. Notably, many clinicians who identify health care problems do not have the time or expertise to solve the problems, and many academic researchers are unaware of important gaps in clinical care to which their expertise may apply.Recognizing an opportunity to connect people who can identify health care problems with those who can solve them, the Yale Center for Biomedical Innovation and Technology (CBIT) was established in 2014 to educate and enhance the impact of health care innovators. Read More

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December 2018
1 Read

Aggressive granulomatosis of the hip: a forgotten mode of aseptic failure.

Int Orthop 2018 Nov 30. Epub 2018 Nov 30.

Hip Surgery Unit, Italian Hospital of Buenos Aires, Institute of Orthopaedics "Carlos E. Ottolenghi", 4247 Potosí St, C1199ACK, Buenos Aires, Argentina.

Purpose: It has been acknowledged that implant wear correlates with the risk for periprosthetic osteolysis, being aggressive granulomatosis the worst expression of bone resorption. We sought to determine the clinical, radiological, and histological features of aggressive granulomatosis after primary total hip arthroplasty (THA).

Methods: We included nine cases with aggressive granulomatosis of the hip around cemented stems. Read More

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November 2018

Increasing Pediatricians' Awareness of the Association between Anal Skin Tags and Earlier Diagnosis of Crohn's Disease.

Inflamm Intest Dis 2018 Nov 4;3(1):40-42. Epub 2018 Oct 4.

Department of Biostatistics, Lenox Hill Hospital, New York, New York, USA.

Objective: To seek the habits of pediatricians by which anorectal skin tags (AST) of Crohn's disease might be overlooked.

Methods: Questionnaires were sent to pediatricians affiliated with the Northwell Health System.

Results: Based on the responses, the majority of pediatricians did feel the abdomen of children presenting with abdominal pain or diarrhea but did not spread the buttocks to seek the presence of AST unless there was rectal pain, rectal bleeding, or, in some cases, loose stools. Read More

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November 2018
3 Reads

A Pilot Analysis of Morphometric Assessment of Itraconazole Brands Using Dermoscopy and its Relevance in the Current Scenario.

Indian Dermatol Online J 2018 Nov-Dec;9(6):426-431

Department of Dermatology and STDs, Dr RML Hospital and PGIMER, New Delhi, India.

Background: Itraconazole (ITZ) is widely used for cutaneous and systemic mycoses. Its bioavailability is inconsistent and shows interindividual variations. The quality of ITZ pellets is an important factor determining its absorption profile and thereby the therapeutic effect. Read More

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December 2018

Remaining Loose Bodies after Arthroscopic Surgery Including Extensive Capsulectomy for Synovial Chondromatosis of the Hip.

Clin Orthop Surg 2018 Dec 21;10(4):393-397. Epub 2018 Nov 21.

Department of Orthopedic Surgery, Seoul National University Bundang Hospital, Seongnam, Korea.

Background: The purpose of our study was to evaluate the usefulness of hip arthroscopy including extensive capsulectomy for synovial chondromatosis of the hip.

Methods: From 2008 to 2016, 13 patients with synovial chondromatosis of the hip were treated with arthroscopic removal of loose bodies and synovectomy using three arthroscopic portals. An extensive capsulectomy was performed to allow the remaining loose bodies to be out of the extracapsular space, and the excised capsule was not repaired. Read More

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December 2018

Comparison of wormlions and their immediate habitat under man-made and natural shelters: suggesting factors making wormlions successful in cities.

Zoology (Jena) 2018 Oct 29;130:38-46. Epub 2018 Aug 29.

School of Zoology, Faculty of Life Sciences & Steinhardt Museum of Natural History and National Research Center, Tel Aviv University, Tel Aviv, Israel. Electronic address:

Wormlions are fly larvae that construct pit-traps in loose soil and ambush prey that fall into their pits. They occur in high numbers in cities, below any man-made shelter providing protection from direct sunlight, such as a concrete roof with a thin layer of sand at the ground. Their natural habitat is either caves or any natural structure that provides full shade. Read More

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October 2018

High-Rate Nanostructured Pyrite Cathodes Enabled by Fluorinated Surface and Compact Grain Stacking via Sulfuration of Ionic Liquid Coated Fluorides.

ACS Nano 2018 Dec 5. Epub 2018 Dec 5.

Metal-polysulfide batteries are attracting broad attentions as conversion reaction systems of high theoretical energy density and low cost. However, their further applications are hindered by low loading of active species, excess conductive additive and loose (nanostructured) electrode network. Herein, we propose that compact grain stacking and surface fluorination are two crucial factors for achieving high-rate and long-life pyrite (FeS2) cathode enabled by sulfurating ionic liquid wrapped open framework fluorides. Read More

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December 2018
1 Read

SUMOylation of Periplakin is critical for efficient re-organization of Keratin filament network.

Mol Biol Cell 2018 Dec 5:mbcE18040244. Epub 2018 Dec 5.

Nups and SUMO Biology Group, Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Bhopal, Madhya Pradesh, India.

The architecture of the cytoskeleton and its remodeling are tightly regulated by dynamic reorganization of keratin-rich intermediate filaments. Plakin family proteins associate with the network of intermediate filaments (IFs) and affect its reorganization during migration, differentiation, and response to stress. The smallest plakin, periplakin (PPL), interacts specifically with intermediate filament proteins K8, K18, and vimentin via its C-terminal linker domain. Read More

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December 2018

Elastic fiber fragmentation increases transmural hydraulic conductance and solute transport in mouse arteries.

J Biomech Eng 2018 Dec 5. Epub 2018 Dec 5.

Department of Mechanical Engineering and Materials Science, Washington University, One Brookings Dr., CB 1185, St. Louis, MO 63130.

Transmural advective transport of solute and fluid was investigated in mouse carotid arteries with either a genetic knockout of Fibulin-5 (Fbln5-/-) or treatment with elastase to determine the influence of a disrupted elastic fiber matrix on wall transport properties. Fibulin-5 is an important director of elastic fiber assembly. Arteries from Fbln5-/- mice have a loose, non-continuous elastic fiber network and were hypothesized to have reduced resistance to advective transport. Read More

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December 2018

On the median pharyngeal valve of the American alligator (Alligator mississippiensis).

J Morphol 2018 Dec 5. Epub 2018 Dec 5.

Department of Biology, University of Maryland, College Park, Maryland.

The middle ear cavities of crocodilians have complex connections with the pharyngeal lumen, including lateral and median components which both open into a single chamber located on the dorsal midline of the pharynx. This chamber and the surrounding soft-tissue is herein termed the median pharyngeal valve. In the American alligator (Alligator mississippiensis) this valve opens, for a duration of 0. Read More

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December 2018
3 Reads

Post-failure behavior analysis of the Shenzhen "12.20" CDW landfill landslide.

Waste Manag 2019 Jan 15;83:171-183. Epub 2018 Nov 15.

Key Laboratory of Shale Gas and Geoengineering, Institute of Geology and Geophysics, Chinese Academy of Sciences, China.

Since the 1990s, with rapid economic development and urbanization occurring in many countries, the amount of construction and demolition waste (CDW) has also increased. Landfills have become the most commonly used method of disposing of CDW. The safety of landfill slopes is very important. Read More

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January 2019

Influence of wood ash pre-treatment on leaching behaviour, liming and fertilising potential.

Waste Manag 2019 Jan 13;83:113-122. Epub 2018 Nov 13.

Technical University of Denmark, Department of Environmental Engineering, Building 113, Miljoevej, 2800 Kgs. Lyngby, Denmark.

In Denmark, increasing amounts of woody biomass are being used for the production of renewable energy, resulting in more wood ashes being generated. While these materials have been mainly landfilled, wood ashes may also be utilised for fertilizing and liming purposes on top of soils. Pre-treatments involving hardening or granulation may be carried out prior to soil application. Read More

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January 2019
2 Reads

Using Evidence-Based Dentistry in the Clinical Management of Combined Periodontal Conditions.

J Evid Based Dent Pract 2018 Dec 13;18(4):290-297. Epub 2018 Feb 13.

Department of Periodontology, Tufts University School of Dental Medicine, Boston, MA, USA.

Objective: This report proposes a framework to integrate evidence-based dentistry (EBD) in a systematic approach in the clinical management of a patient diagnosed with drug-induced gingival hyperplasia combined with generalized aggressive periodontitis.This report illustrates the case of a 37-year-old female who presented to the Department of Periodontology at Tufts University School of Dental Medicine with enlarged, tender, bleeding gums, and loose teeth combined with a history of uncontrolled hypertension treated with calcium channel blockers.

Methods: Incorporating the EBD process, a new 5-step framework is proposed: ask the clinical question, acquire and appraise the evidence, apply it in the clinical setting, and assess the subjective and objective outcomes. Read More

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December 2018
3 Reads

Media Dependent Switching of Selectivity and Continuous Near Infrared Turn-on Fluorescence Response through Cascade Interactions from Noncovalent to Covalent Binding for Detection of Serum Albumin in Living Cells.

ACS Appl Mater Interfaces 2018 Dec 4. Epub 2018 Dec 4.

Abnormal level of proteins is proved to be associated with diseases. Thus, protein sensing is helpful for clinical diagnosis and therapy. However, there is a great variety of protein species and relatively low concentration of each protein in complicated biological systems including other non-protein biomolecules. Read More

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December 2018

[Key anatomies of DeLancey's three levels of vaginal support theory: an observation in laparoscopic surgery].

Zhejiang Da Xue Xue Bao Yi Xue Ban 2018 Feb;47(4):329-337

Center for Uterine Cancer Diagnosis & Therapy Research of Zhejiang Province, Department of Oncology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.

Objective: To observe and verify the key anatomies of DeLancey's three levels of vaginal support theory through laparoscopic surgery by space dissection technique.

Methods: The features and stress performance of related anatomies were observed and analyzed in laparoscopic type C hysterectomy and pelvic lymphadenectomy for cervical cancer by natural space exposures.

Results: The main ligament-like structure at level Ⅰ was the uterosacral ligament, which acted as the main apical fixation in the sacral direction, while the cardinal ligament was mainly composed of vascular system, lymph-vessels and loose connective tissue around them, lacking the tough connective tissue structures, which was connected to the internal iliac vascular system. Read More

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February 2018

Large B-cell lymphoma concommittant to intra-cerebral hemorrhage.

Cytopathology 2018 Nov 30. Epub 2018 Nov 30.

Service d'Hématologie Biologique, University Hospital, Nancy, France.

A 63-year old man presented with intra-cerebral hemorrhage (ICH) confirmed by tomodensitometry. The cerebrospinal fluid (CSF) examination showed a xanthochromic liquid with 1.537 x 10 /L nucleated cells (Body Fluid mode, Sysmex XN-9000, Roissy, Fr), increased red blood cells (RBCs), loose clusters of leptomeningeal cells (fig 1) macrophages and abnormal lymphocytes (fig 2). Read More

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November 2018
3 Reads

Neurotoxicological effects induced by up-regulation of miR-137 following triclosan exposure to zebrafish (Danio rerio).

Aquat Toxicol 2018 Nov 22;206:176-185. Epub 2018 Nov 22.

Zhejiang Provincial Key Laboratory of Medical Genetics, Key Laboratory of Laboratory Medicine, Ministry of Education, China, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China. Electronic address:

Triclosan (TCS) is a prevalent anthropogenic contaminant in aquatic environments and its chronic exposure can lead to a series of neurotoxic effects in zebrafish. Both qRT-PCR and W-ISH identified that TCS exposure resulted in significant up-regulation of miR-137, but downregulation of its regulatory genes (bcl11aa, MAPK6 and Runx1). These target genes are mainly associated with neurodevelopment and the MAPK signaling pathway, and showed especially high expression in the brain. Read More

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November 2018

Metal-organic framework as an efficient filter for the removal of heavy metal cations in water.

Phys Chem Chem Phys 2018 Nov 29. Epub 2018 Nov 29.

State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), and Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou 215123, China and IBM Thomas J. Watson Research Center, Yorktown Heights, NY 10598, USA. and Department of Chemistry, Columbia University, New York, NY 10027, USA.

Heavy metal ions from water and wastewater are non-biodegradable and tend to accumulate in the soil and living organisms, polluting the environment and causing serious health hazards in humans. Therefore, effective treatment of heavy metal ions in aqueous media is critical for public health and environmental sustainability. In this paper, we employ molecular dynamics simulations to investigate the removal efficiency of heavy metal cations (Cd2+, Hg2+, and Pb2+) by a zirconium phosphonate based metal-organic framework (MOF) filter and also to explore its underlying molecular mechanism. Read More

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November 2018

Ectopic Organogenesis after Allotransplantation of Freshly Removed or Cryopreserved Neonatal Testicle under the Renal Capsule in Rats.

Bull Exp Biol Med 2018 Dec 28;166(2):268-273. Epub 2018 Nov 28.

All-Russian Institute of Scientific and Technical Information, Russian Academy of Sciences, Moscow, Russia.

In experiments on white outbred male rats, a freshly removed (20 experiments) or cryopreserved (10 experiments) testicle from newborn rats (1-2 days after birth) was transplanted under the renal capsule after bilateral orchiectomy. In all experiments with transplantation of freshly removed testicle, it was engrafted. In 3 months, histological examination revealed the formation of mature seminiferous tubules, but spermatogenesis was blocked at the stage of spermatogonia; groups of proliferating Leydig cells in the loose connective tissue between the tubules were also seen. Read More

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December 2018
2 Reads

Mechanisms of abrupt loss of virus control in a cohort of previous HIV controllers.

J Virol 2018 Nov 28. Epub 2018 Nov 28.

IrsiCaixa AIDS Research Institute - HIVACAT, Hospital Universitari Germans Trias i Pujol, Badalona, Spain

Elite and Viremic HIV controllers are able to control their HIV infection and maintain undetectable or low-level viremia in the absence of antiretroviral treatment. Despite extensive studies, the immune factors responsible for such exclusive control remain poorly defined. We identified a cohort of 14 HIV controllers that suffered an abrupt loss of HIV control (LoC) to investigate possible mechanisms and virological and immunological events related to the sudden loss of control. Read More

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November 2018
2 Reads

Impact of and Polymorphisms on Warfarin Sensitivity and Responsiveness in Jordanian Cardiovascular Patients during the Initiation Therapy.

Genes (Basel) 2018 Nov 27;9(12). Epub 2018 Nov 27.

Department of Hematopathology, King Hussein Medical Center (KHMC), Jordan Royal Medical Services (RMS), Amman 11118, Jordan.

Warfarin is an oral anticoagulant frequently used in the treatment of different cardiovascular diseases. Genetic polymorphisms in the and genes have produced variants with altered catalytic properties. A total of 212 cardiovascular patients were genotyped for 17 Single Nucleotide Polymorphisms (SNPs) within the and genes. Read More

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November 2018
1 Read

The hydrophobic nature of a novel membrane interface regulates the enzyme activity of a voltage-sensing phosphatase.

Elife 2018 Nov 28;7. Epub 2018 Nov 28.

Department of Physiology, Graduate School of Medicine, Osaka University, Suita, Japan.

Voltage-sensing phosphatases (VSP) contain a voltage sensor domain (VSD) similar to that of voltage-gated ion channels but lack a pore-gate domain. A VSD in a VSP regulates the cytoplasmic catalytic region (CCR). However, the mechanisms by which the VSD couples to the CCR remain elusive. Read More

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November 2018

Recurrence of Patellar Instability in Adolescents Undergoing Surgery for Osteochondral Defects Without Concomitant Ligament Reconstruction.

Am J Sports Med 2018 Nov 28:363546518808486. Epub 2018 Nov 28.

Department of Orthopedic Surgery, University of California, San Diego, California, USA.

Background:: First-time patellar dislocation with an associated chondral or osteochondral loose body is typically treated operatively to address the loose fragment. The incidence of recurrent instability in this patient population if the medial patellofemoral ligament (MPFL) is not reconstructed is unknown.

Purpose:: To determine the recurrent instability rate in patients undergoing surgery for patellar instability with chondral or osteochondral loose bodies, as well as to identify and stratify risk factors for recurrent instability. Read More

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November 2018

Roaming-Like Mechanism for Dehydration of Diol Radicals.

J Phys Chem A 2018 Nov 28. Epub 2018 Nov 28.

Diol radicals (DRs) are important intermediates in biocatalysis, atmospheric chemistry and biomass combustion. They are particularly generated from photolysis of halogenated diols and a barrierless addition of hydroxyl radical to a double bond of unsaturated alcohols, such as lignols. The energized DRs further isomerize / decompose to form products, including water. Read More

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November 2018

Understanding the Binding of a Bifunctional Amidoximate-Carboxylate Ligand With Uranyl in Seawater.

J Phys Chem B 2018 Nov 28. Epub 2018 Nov 28.

Extracting uranium from seawater remains a formidable challenge due to its extremely low concentration at 3.3 ppb. State-of-the-art polymeric sorbents employ both amidoximate and carboxylate groups on the side chains to achieve optimal U uptake and selectivity, but little is known about the synergistic effect between the two functional groups in binding with uranyl. Read More

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November 2018

Better Healing of the Exit Site with Negative-Pressure Wound Therapy.

Adv Perit Dial 2018 Nov;34(2018):53-57

Division of Nephrology, Endocrinology, and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.

Exit-site infection poses a risk for peritonitis and can shorten peritoneal dialysis (PD) vintage. A loose fit of the skin around the catheter at the exit site can push bacteria surrounding the catheter into the subcutaneous tunnel. Negative-pressure wound therapy (NPWT) has been used to hasten healing of the wound after an operation or to treat pressure ulcers. Read More

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November 2018
5 Reads

Three-Dimensional Chestnut-like Architecture Assembled from NaTi3O6(OH)·2H2O@N-Doped Carbon Nanosheets with Enhanced Sodium Storage Properties.

ACS Appl Mater Interfaces 2018 Nov 27. Epub 2018 Nov 27.

The application of sodium titanates anodes of low cost, feasible operate voltage and non-toxicity were severely hindered by the inferior cycling stability and poor rate capability. Here, three-dimensional chestnut-like NaTi3O6(OH)·2H2O@N-doped carbon nanospheres (NTOH @CN) with loose crystal structure were prepared by self-sacrificed template method. The nanospheres were composed of nanosheets and linked with nanowires, which interweaved to construct a meshwork structure. Read More

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November 2018
1 Read

Dclk1 in tuft cells promotes inflammation-driven epithelial restitution and mitigates chronic colitis.

Cell Death Differ 2018 Nov 26. Epub 2018 Nov 26.

Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 73104, USA.

Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by defective intestinal barrier integrity toward the microbiota and epithelial damage. Double cortin-like kinase 1 (Dclk1), a marker of intestinal tuft cells, can regulate tissue regenerative responses, but its role in epithelial repair during bacterial-dependent chronic colitis is unclear. We addressed this question using our recently developed mouse model of spontaneous microbiota-dependent colitis induced by mucin-type O-glycan deficiency (DKO), which recapitulates most features of human UC. Read More

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November 2018
11 Reads

Structural characteristics of cake layer in membrane bioreactor with chromate exposure.

Ecotoxicol Environ Saf 2018 Nov 23;169:583-589. Epub 2018 Nov 23.

State Key Laboratory of Pollution Control and Resource Reuse, Shanghai Institute of Pollution Control and Ecological Security, College of Environmental Science and Engineering, Tongji University, 1239 Siping Road, Shanghai 200092, PR China. Electronic address:

Chromate (CrO) exposure, especially high concentration (mg/L), still probably occurs in the industrial and mining area due to industrial accidents or even illegal discharge, though CrO has been restricted to be discharged into wastewater treatment system (WWTS). Therefore, this study was applied to better understand the structural characteristics of cake layer in membrane bioreactor (MBR), which is one of best alternative for WWTS of industrial or mining area, with CrO exposure. Three submerged MBRs with CrO exposure (10 mg/L was normal high concentration CrO; 50 mg/L as extreme level for better identification; 0 mg/L as control condition) were applied in this study. Read More

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November 2018

An acoustic emission characterization of the failure process of shallow foundation resting on sandy soils.

Ultrasonics 2018 Nov 22;93:107-111. Epub 2018 Nov 22.

Department of Civil Engineering, The University of Tokyo, Tokyo 113-8656, Japan.

Shallow foundation is a common foundation type that is usually used for small to medium size structures. The bearing ability and the failure mechanism of shallow foundation are the fundamental concerns for geotechnical engineers, and the demand for new insights into the relevant issue is still increasing. This paper presents an acoustic emission (AE) characterization of the failure process of shallow foundation, with the aim of revealing the fundamental information on AE signals associated with shallow foundation loading as well as its connection with the ground bearing behavior. Read More

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November 2018
1.800 Impact Factor

A novel mutation causing recessive cutis laxa with unusual manifestations of bleeding diathesis and defective wound healing.

Turk J Haematol 2018 Nov 26. Epub 2018 Nov 26.

Department of Molecular Biology-Genetics and Biotechnology, Graduate School of Science, Engineering and Technology, Istanbul Technical University, Turkey.

Objective: Autosomal recessive cutis laxa type IIA (ARCL2A) is a rare congenital disorder characterized by loose and elastic skin, growth and developmental delay, and skeletal anomalies. It is caused by biallelic mutations in . Those mutations lead to increased pH in secretory vesicles and thereby to impaired glycosyltransferase activity and organelle trafficking. Read More

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November 2018
2 Reads

Two new species of A. Adams, 1868 from Taiwan (Pulmonata, Camaenidae).

Zookeys 2018 8(795):115-126. Epub 2018 Nov 8.

Department of Earth and Life Sciences, University of Taipei, No.1, Ai-Guo West Road, Taipei 10048, Taiwan University of Taipei Taipei Taiwan.

Two new sinistral species of the genus A. Adams, 1868, and , from southern Taiwan are described. is characterized by a microsculpture comprising coarse, irregularly-spaced ridges and dense, easily-dislodged triangular scales on its sinistral shell, an angulated periphery, and partly-opened umbilicus. Read More

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November 2018
2 Reads

Daily administration of a GnRH analogue enhances sperm quality in bucks during the non-breeding season.

Anim Reprod Sci 2018 Nov 19. Epub 2018 Nov 19.

Departamento de Fisiología, Facultad de Veterinaria, Universidad de la República, Montevideo, Uruguay.

The aim of this study was to determine if daily administration of a GnRH analogue (buserelin acetate) to bucks during the non-breeding season increases testosterone concentration and improves sperm quality. Five bucks received a daily dose of buserelin for 10 days, starting on Day 0 (first administration), and another five bucks remained as controls. Testosterone concentrations were greater in treated than in control bucks during the first hours after buserelin administration (P = 0. Read More

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November 2018
1 Read

Selection of egg peptide biomarkers in processed food products by high resolution mass spectrometry.

J Chromatogr A 2018 Nov 20. Epub 2018 Nov 20.

CER Groupe, Rue du Point du Jour 8, 6900, Marloie, Belgium.

Food allergy is a growing health problem worldwide; thus, there is an urgent need for robust, specific, and sensitive analytical methods for detecting allergens. Mass spectrometry is an alternative to the existing methods, and it can overcome their limitations. One of the first steps in the development of any analytical method is the identification of the analytes to be further studied. Read More

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November 2018
6 Reads

Wide Awake Secondary Tendon Reconstruction.

Hand Clin 2019 Feb;35(1):35-41

Division of Plastic and Reconstructive Surgery, Stanford University Medical Center, 770 Welch Road, Suite 400, Palo Alto, CA 94304, USA.

The wide awake anesthesia technique is a useful tool in secondary tendon reconstruction. With active participation of the patient, the tendon repair can be adjusted appropriately to prevent repairs that are too tight or too loose. Areas of tendon scarring or triggering can be identified and released. Read More

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February 2019
2 Reads

The low protein diet affects the nonspecific inflammatory response of middle-aged and old mice through mTOR.

Eur Rev Med Pharmacol Sci 2018 Nov;22(21):7551-7561

Department of Pathophysiology, Basic Medical College, Shanxi Medical University, Taiyuan, Shanxi, China.

Objective: To explore the effect of low protein diet on nonspecific inflammatory changes in mice during aging and related mechanisms.

Materials And Methods: Thirty-two 14-month-old female KM mice were randomly divided into 4 groups: control group, low protein group, high protein group, high protein + rapamycin group. Hematoxylin-eosin (HE) staining was performed to observe the pathological changes of the liver. Read More

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November 2018
1 Read

Usefulness of MR Arthrography of the Hip with and without leg Traction in Detection of Intra-articular Bodies.

Acad Radiol 2018 Nov 19. Epub 2018 Nov 19.

Department of Orthopaedic Surgery, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse, CH-3010 Bern, Switzerland. Electronic address:

Rationale And Objective: Although intra-articular bodies are a classic indication for MR arthrography and surgical removal, diagnostic studies are currently sparse. To assess the diagnostic performance of MR arthrography with and without leg traction in detection of intra-articular bodies in the hip joint.

Material And Methods: The institutional hip arthroscopy data base (2009-2016: 631 hips) was retrospectively reviewed. Read More

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November 2018

Enhanced basal autophagy supports ameloblastoma-derived cell survival and reactivation.

Arch Oral Biol 2018 Nov 14;98:61-67. Epub 2018 Nov 14.

Department of Oral Medicine, School of Dental Medicine, University of Pennsylvania, Philadelphia PA USA. Electronic address:

Objectives: Ameloblastoma is an aggressive odontogenic jaw neoplasm. Its unlimited growth confers high potential for malignant transformation and recurrence. It is unclear why ameloblastoma is highly recurrent despite surgical resection with a wide margin of normal tissue. Read More

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November 2018
1 Read

Echocardiographic Guidance During Neonatal and Pediatric Jugular Cannulation for ECMO.

J Surg Res 2018 Dec 3;232:517-523. Epub 2018 Aug 3.

Indiana University School of Medicine, Department of Surgery, Section of Pediatric Surgery, Indianapolis, Indiana. Electronic address:

Background: Internal jugular vein extracorporeal membrane oxygenation (ECMO) cannula position is traditionally confirmed via plain film. Misplaced cannulae can result in need for repositioning and increased morbidity. Echocardiography (ECHO) may be used during cannulation as a more accurate means of guiding cannula position. Read More

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December 2018
2 Reads

Variability of subsurface structure and infiltration hydrology among surface coal mine valley fills.

Sci Total Environ 2019 Feb 13;651(Pt 2):2648-2661. Epub 2018 Oct 13.

Department of Geosciences, Virginia Polytechnic Institute and State University, 5041 Derring Hall, Blacksburg, VA 24061, United States of America.

Surface coal mining alters landscapes including creating waste-rock fills or dumps. In Appalachia USA, mines fill valleys with waste rock, constructing valley fills that affect water quality and aquatic ecology downstream. Total dissolved solids (TDS) in mine effluent are elevated from exposure of mineral surfaces to weathering. Read More

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February 2019
3 Reads

BulkVis: a graphical viewer for Oxford nanopore bulk FAST5 files.

Bioinformatics 2018 Nov 20. Epub 2018 Nov 20.

School of Life Sciences, University of Nottingham, Nottingham NG7 2UH, UK.

Motivation: The Oxford Nanopore Technologies (ONT) MinION is used for sequencing a wide variety of sample types with diverse methods of sample extraction. Nanopore sequencers output FAST5 files containing signal data subsequently base called to FASTQ format. Optionally, ONT devices can collect data from all sequencing channels simultaneously in a bulk FAST5 file enabling inspection of signal in any channel at any point. Read More

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November 2018
8 Reads

Dye-embedded YAG:Ce@SiO composite phosphors toward warm wLEDs through radiative energy transfer: preparation, characterization and luminescence properties.

Nanoscale 2018 Dec 21;10(47):22237-22251. Epub 2018 Nov 21.

State Key Laboratory of Luminescence and Applications, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, 3888 Dong Nanhu Road, Changchun 130033, China.

The most common yellow phosphor for wLEDs, YAlO:Ce (YAG:Ce), suffers from a deficiency of red in its spectral content of light. In this paper, a new strategy is provided to tailor the Ce spectral profile through surface-located dye molecules of ATTO-Rho101, which feature intense, broad absorption in the green-yellow spectral region of Ce emission as well as bright red emission. Sphere-shaped and highly dispersed micrometer and nanometer-sized YAG:Ce (micro/nano-YAG:Ce) was synthesized through a modified solvothermal method. Read More

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December 2018
5 Reads

Letters.

Nursing 2018 Dec;48(12)

GULFPORT, MISS. MOORESVILLE, IND. CHICAGO, ILL.

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December 2018
1 Read