Heart Rhythm 2022 Jun 13. Epub 2022 Jun 13.
Department of Molecular Pharmacology & Experimental Therapeutics (Windland Smith Rice Sudden Death Genomics Laboratory), Mayo Clinic, Rochester, Minnesota; Department of Cardiovascular Medicine (Division of Heart Rhythm Services, Windland Smith Rice Genetic Heart Rhythm Clinic), Mayo Clinic, Rochester, Minnesota; Department of Pediatric and Adolescent Medicine (Division of Pediatric Cardiology), Mayo Clinic, Rochester, Minnesota. Electronic address:
Background: Beta blockers (BBs), sodium channel blockers (SCBs), left cardiac sympathetic denervation (LCSD), and implantable cardioverter defibrillators (ICDs) are used to prevent or counter long QT syndrome (LQTS)-triggered syncope, seizures, and sudden cardiac death (SCD). The spectrum and extent of side effects/complications associated with these guideline-directed therapies (GDTs) remain unknown.
Objective: Identify the types/prevalence of treatment-associated side effects/complications for patients with the most common LQTS subtypes following GDT. Read More