163 results match your criteria Local and Regional Anesthesia


Control of Spinal Anesthesia-Induced Hypotension in Adults.

Local Reg Anesth 2020 3;13:39-46. Epub 2020 Jun 3.

Department of Anesthesia and Intensive Care Medicine, CHU Purpan, Toulouse, France.

Spinal anesthesia-induced hypotension (SAIH) occurs frequently, particularly in the elderly and in patients undergoing caesarean section. SAIH is caused by arterial and venous vasodilatation resulting from the sympathetic block along with a paradoxical activation of cardioinhibitory receptors. Bradycardia after spinal anesthesia (SA) must always be treated as a warning sign of an important hemodynamic compromise. Read More

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http://dx.doi.org/10.2147/LRA.S240753DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276328PMC

Delayed Neurological Recovery After Ultrasound-Guided Brachial Plexus Block: A Case Report [Letter].

Local Reg Anesth 2020 2;13:37-38. Epub 2020 Jun 2.

Department of Anesthesiology, New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY, USA.

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http://dx.doi.org/10.2147/LRA.S260021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276338PMC

Delayed Neurological Recovery After Ultrasound-Guided Brachial Plexus Block: A Case Report.

Local Reg Anesth 2020 23;13:33-35. Epub 2020 Apr 23.

Department of Anaesthesia, Maharajgunj Medical Campus, Institute of Medicine, Maharajgunj, Kathmandu, Nepal.

Introduction: Brachial plexus blocks are frequently practiced and safe mode of anaesthsia. Although minor complications may occur, major complications are a rarity. However, we report a rare case of prolonged supraclavicular brachial plexus block which required almost 4 months to recover without a perceivable cause. Read More

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http://dx.doi.org/10.2147/LRA.S250989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187543PMC

Ankle Surgery in a Patient with Acute Subdural Hematoma Under Combined Lumbar Plexus and Proximal Sciatic Nerve Block - A Case Report.

Local Reg Anesth 2020 15;13:29-32. Epub 2020 Apr 15.

Department of Anaesthesiology, Tribhuvan University Teaching Hospital, Institute of Medicine, Tribhuvan University, Kathmandu, Nepal.

Acute subdural hematoma (aSDH) is commonly encountered in the emergency department in patients with traumatic injuries. If the hematoma is small, non-expanding and asymptomatic, it is managed conservatively. However, other injuries sustained during trauma may warrant surgical intervention, during which anesthetic management becomes challenging. Read More

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http://dx.doi.org/10.2147/LRA.S247413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7167266PMC

Safety and Efficacy of Oral Melatonin When Combined with Thoracic Epidural Analgesia in Patients with Bilateral Multiple Fracture Ribs.

Local Reg Anesth 2020 14;13:21-28. Epub 2020 Apr 14.

Department of Anesthesia, ICU and Pain Relief, South Egypt Cancer Institute, Assiut University, Assiut, Egypt.

Background: The purpose of this study is to evaluate the safety and efficacy of oral melatonin administered with thoracic epidural analgesia in patients with multiple bilateral fractured ribs.

Patients and methods: A prospective, double-blind randomized control study was carried out on 80 patients of either sex, American Society of Anesthesiologists (ASA) Grade I and II, aged above 18 years, presenting with multiple bilateral fractured ribs. They were randomly divided into two groups, 40 patients each. Read More

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http://dx.doi.org/10.2147/LRA.S244510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7166071PMC

Opioid-Free Cesarean Section with Bilateral Quadratus Lumborum Catheters.

Local Reg Anesth 2020 7;13:17-20. Epub 2020 Feb 7.

Department of Anesthesiology, University of Texas Health Science Center at Houston, Houston, TX, USA.

Introduction: Post-operative pain control following cesarean section delivery (CD) is an important topic of discussion given the lack of consensus on a narcotic-sparing analgesic regimen. We describe the case of an elective CD with narcotic-free pain control using continuous bilateral posterior quadratus lumborum (QL) blockade as the primary mode of analgesia.

Case Report: The patient is a 36-year-old female, G3P1, who presented at 37 weeks of gestation in active labor scheduled for elective primary CD. Read More

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http://dx.doi.org/10.2147/LRA.S238026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012325PMC
February 2020

Peripheral Neuropathic Pain and Pain Related to Complex Regional Pain Syndrome with and without Fixed Dystonia - Efficient Therapeutic Approach with Local Anesthetics.

Authors:
Thomas Michels

Local Reg Anesth 2020 31;13:11-16. Epub 2020 Jan 31.

Internal Medicine, Hematology, Radiology, Natural Cure, Cologne (Köln) 50968, Germany.

Peripheral Neuropathic Pain (PNP) as well as the Complex Regional Pain Syndrome (CRPS), also known as "Reflex Sympathetic Dystrophy", or "Sudeck Dystrophy", all of them have a poor prognosis. The numerous therapeutic offers are rarely accompanied by convincing success over a long duration of time. Even worse is the prognosis of a fixed dystonia which may develop in the extremities of PNP or CRPS patients. Read More

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http://dx.doi.org/10.2147/LRA.S229315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999782PMC
January 2020

Non-Operating Room Anesthesia: Patient Selection and Special Considerations.

Local Reg Anesth 2020 8;13:1-9. Epub 2020 Jan 8.

Department of Anesthesiology, Department of Orthopaedics and Rehabilitation (by Courtesy), Department of Surgery (by Courtesy), University of Vermont Larner College of Medicine, Burlington, VT, USA.

Non-operating room anesthesia (NORA) represents a growing field of medicine with an increasing trend in the number of cases performed over the previous decade. As a result, anesthesia providers will need to enhance their familiarity with the resources, personnel, and environment outside of the operating room. Anesthesia delivery in NORA settings should be held with the same high-quality standards as that within the operating room. Read More

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http://dx.doi.org/10.2147/LRA.S181458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956865PMC
January 2020

Long-term placement of continuous popliteal nerve block catheter for management of a wounded patient in a combat field environment: a case report.

Local Reg Anesth 2019 29;12:67-70. Epub 2019 Aug 29.

Intensive Care Unit and Anestehsia, Università degli Studi di Parma, Parma, Italy.

Continuous peripheral nerve block is a relevant part of multimodal treatment of postoperative pain. In this context the continuous popliteal nerve block is described as an option for postoperative pain management for surgical procedures on the leg, and particularly on the ankle and foot. We applied continuous popliteal nerve block for different types of anesthesia and postoperative pain management via the same catheter. Read More

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http://dx.doi.org/10.2147/LRA.S210462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718249PMC

Anesthesia for Percutaneous Radiofrequency Tumor Ablation (PRFA): A Review of Current Practice and Techniques.

Local Reg Anesth 2019 4;12:127-137. Epub 2019 Dec 4.

Department of Critical and Supportive Care, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

Percutaneous radiofrequency ablation (PRFA) of solid tumors is a minimally invasive procedure used to treat primary or metastatic cancer lesions via needle targeted thermal energy transfer. Some of the most common tumor lesions treated using PRFA include those within the liver, lungs and kidneys. Additionally, bone, thyroid, and breast lesions can also be treated. Read More

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http://dx.doi.org/10.2147/LRA.S185765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900282PMC
December 2019

Bilateral Brachial Plexus Block Using Chloroprocaine For Surgery Of Bilateral Radial Fractures [Response To Letter].

Local Reg Anesth 2019 21;12:125-126. Epub 2019 Nov 21.

Department of Anesthesiology, New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY, USA.

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http://dx.doi.org/10.2147/LRA.S238432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877540PMC
November 2019

Obesity And Obstetric Anesthesia: Current Insights.

Local Reg Anesth 2019 18;12:111-124. Epub 2019 Nov 18.

Department of Anesthesiology, Division of Women's Anesthesia, Duke University, Durham, NC 27710, USA.

Obesity is a significant global health problem. It results in a higher incidence of complications for pregnant women and their neonates. Cesarean deliveries are more common in obese parturients as well. Read More

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http://dx.doi.org/10.2147/LRA.S186530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873959PMC
November 2019

Bilateral Brachial Plexus Block Using Chloroprocaine For Surgery Of Bilateral Radial Fractures [Letter].

Local Reg Anesth 2019 8;12:109-110. Epub 2019 Nov 8.

Department Anaesthesia, Pain and Palliative Medicine, Radboud University Medical Center, Nijmegen, 6500 HB, the Netherlands.

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http://dx.doi.org/10.2147/LRA.S233411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850673PMC
November 2019

Case Report Of Cryoneurolysis For The Treatment Of Refractory Intercostobrachial Neuralgia With Postherpetic Neuralgia.

Local Reg Anesth 2019 1;12:103-107. Epub 2019 Nov 1.

Department of Anesthesiology, New York Medical College, Valhalla, NY, USA.

Postherpetic neuralgia is a common and potentially debilitating neuropathic pain condition. Current pharmacologic therapy can be inadequate and intolerable for patients. We present a case of a gentleman with refractory postherpetic neuralgia in the intercostobrachial nerve distribution that was successfully treated with cryoneurolysis/cryoanalgesia therapy. Read More

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http://dx.doi.org/10.2147/LRA.S223961DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830355PMC
November 2019

Effect of bupivacaine and adjuvant drugs on skeletal muscle tissue oximetry and blood flow: an experimental study.

Local Reg Anesth 2019 29;12:71-80. Epub 2019 Aug 29.

Department of Anesthesiology and Intensive Care Medicine, University Hospital Marburg, Philipps University of Marburg, Marburg, Germany.

Background: Skeletal muscle microvascular blood flow plays a critical role in many myopathologies. The influence of bupivacaine and adjuvants on skeletal muscle microvascular perfusion and tissue oximetry is poorly understood but might be a relevant risk factor for myopathies after local anesthetic administration. The aim of this experimental study was to determine the effects of bupivacaine alone or in combination with epinephrine or clonidine on skeletal muscle perfusion and tissue oximetry. Read More

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http://dx.doi.org/10.2147/LRA.S203569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718243PMC

Erratum: Evaluation Of The Attitudes Of Surgeons About Regional Anesthesia: A Survey Study [Corrigendum].

Authors:

Local Reg Anesth 2019 30;12:97. Epub 2019 Sep 30.

[This corrects the article DOI: 10.2147/LRA.S211469. Read More

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http://dx.doi.org/10.2147/LRA.S231688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778320PMC
September 2019

Bilateral Brachial Plexus Block Using Chloroprocaine For Surgery Of Bilateral Radial Fractures.

Local Reg Anesth 2019 27;12:99-102. Epub 2019 Sep 27.

Department of Anesthesiology, New York Presbytarian Brooklyn Methodist Hospital, New York, NY, USA.

We report a case of a 41-year-old male with anticipated difficult airway undergoing a repair of a bilateral radial fracture under bilateral sequential brachial plexus block. Anesthesiologists are reluctant to perform bilateral blocks because of the fear of complications like diaphragmatic paralysis, local anesthetic (LA) toxicity, and pneumothorax. We advise that with the correct application of LA pharmacokinetics, careful patient selection and usage of ultrasound, bilateral blocks can be done safely. Read More

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http://dx.doi.org/10.2147/LRA.S225471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773967PMC
September 2019
1 Read

Evaluation of the attitudes of surgeons about regional anesthesia: a survey study.

Local Reg Anesth 2019 16;12:89-95. Epub 2019 Sep 16.

Department of Anesthesiology and Reanimation, Haseki Education and Research Hospital, Istanbul, Turkey.

Background: The intraoperative attending anaesthesiologist ultimately makes decisions about the anaesthesiology technique to be performed, but the attitudes of surgeons and preferences of patients on this subject may affect their choice. In this questionnaire-based study, we aimed to evaluate the attitudes and behaviors of surgeons about the use of regional anaesthesia (RA) in surgical operations.

Methods: Surgeons from different surgical branches with residencies at 4 different hospitals were asked to complete questionnaires that included reasons for preferring (12 reasons) and not preferring (13 reasons) the use of RA techniques for surgeries, using a 5-point Likert scale. Read More

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http://dx.doi.org/10.2147/LRA.S211469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756757PMC
September 2019

Anesthetic techniques: focus on transversus abdominis plane (TAP) blocks.

Local Reg Anesth 2019 5;12:81-88. Epub 2019 Sep 5.

Department of Anaesthesiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Transverse abdominis plane (TAP) blocks, over the past decade, have emerged as a reliable tool in multimodal analgesia. Although they block only the somatic component of pain, studies have still revealed a consistent benefit in the first 24-48 hours after surgery in terms of pain scores and overall opioid consumption. The safety and dependability has increased with ultrasound usage. Read More

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http://dx.doi.org/10.2147/LRA.S138537DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734547PMC
September 2019
1 Read

Impact of serratus plane block on pain scores and incentive spirometry volumes after chest trauma.

Local Reg Anesth 2019 2;12:59-66. Epub 2019 Aug 2.

Department of Anesthesiology, Houston's McGovern Medical School, University of Texas Health Science Center, Houston, TX, 77030, USA.

Adequate pain control is difficult to achieve in patients with multiple rib fractures (MRF). Serratus plane block (SPB) is a novel technique for alleviating rib fracture pain. Several published case reports support this hypothesis. Read More

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http://dx.doi.org/10.2147/LRA.S207791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684485PMC
August 2019
2 Reads

Effect of hypotensive hypovolemia and thoracic epidural anesthesia on plasma pro-atrial natriuretic peptide to indicate deviations in central blood volume in pigs: a blinded, randomized controlled trial.

Local Reg Anesth 2019 25;12:47-55. Epub 2019 Jun 25.

Department of Surgical Gastroenterology.

Purpose: Changes in plasma pro-atrial natriuretic peptide (proANP) may indicate deviations in the central blood volume (CBV). We evaluated the plasma proANP response to hypotensive hypovolemia under the influence of thoracic epidural anesthesia (TEA) in pigs. We hypothesized that plasma proANP would decrease in response to hypotensive hypovolemia and that TEA would aggravate the proANP response, reflecting a further decrease in CBV. Read More

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http://dx.doi.org/10.2147/LRA.S204594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599965PMC
June 2019
5 Reads

Improving intraoperative handoffs for ambulatory anesthesia: challenges and solutions for the anesthesiologist.

Local Reg Anesth 2019 24;12:37-46. Epub 2019 May 24.

Department of Anesthesiology, University of Miami, Miami, FL, USA.

Permanent transitions of care from one anesthesia provider to another are associated with adverse events and mortality. There are currently no available data on how to mitigate these poor patient outcomes other than to reduce the occurrence of such handoffs. We used data from an ambulatory surgery center to demonstrate the steps that can be taken to achieve this goal. Read More

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http://dx.doi.org/10.2147/LRA.S183188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538832PMC
May 2019
3 Reads

Comparison of subcutaneous dexmedetomidine versus clonidine as an adjuvant to spinal anesthesia: a randomized double blind control trial.

Local Reg Anesth 2019 5;12:29-36. Epub 2019 Apr 5.

Department of Anaesthesiology, M.S. Ramaiah Medical College and Hospitals, Bengaluru, 560054, India.

Alpha-2 adrenergic agonists like clonidine and dexmedetomidine prolong the duration of postoperative analgesia and improve the quality of subarachnoid block (SAB) when used as adjuvant in various routes. However, addition of these drugs by IV or intrathecal routes are known to cause hemodynamic instability. The subcutaneous (SC) route provides similar efficacy as IV administration with less hemodynamic instability and prolonged effect. Read More

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http://dx.doi.org/10.2147/LRA.S197386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497827PMC
April 2019
7 Reads

A clearer view on postoperative cognitive dysfunction? [Letter].

Local Reg Anesth 2019 12;12:27-28. Epub 2019 Mar 12.

Department of Anaesthesia, Pain and Palliative Medicine, Radboud University Medical Center, Nijmegen, The Netherlands,

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http://dx.doi.org/10.2147/LRA.S201896DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420101PMC
March 2019
5 Reads

Spinal anesthesia-induced hypotension is caused by a decrease in stroke volume in elderly patients.

Local Reg Anesth 2019 4;12:19-26. Epub 2019 Mar 4.

Department of Anesthesia, Radboud University Medical Center, Nijmegen, The Netherlands.

Background: Hypotension is common during spinal anesthesia (SA) and is caused by a decrease in systemic vascular resistance (SVR) and/or cardiac output (CO). The effect of the dose of bupivacaine administered intrathecally on the changes in CO in elderly patients is largely unknown. This study investigated the hemodynamic effect of SA in elderly patients by studying the effect of two different dosages of intrathecal bupivacaine. Read More

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http://dx.doi.org/10.2147/LRA.S193925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404676PMC
March 2019
6 Reads

Celiac plexus block as a diagnostic tool in suspected pediatric median arcuate ligament syndrome.

Local Reg Anesth 2019 27;12:15-18. Epub 2019 Feb 27.

Department of Anesthesiology, New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY, USA,

We report the use of celiac plexus block (CPB) as a diagnostic aid in the evaluation of median arcuate ligament syndrome (MALS) in a pediatric patient. MALS is a rare cause of severe, debilitating, abdominal postprandial pain associated with nausea, vomiting, occasional diarrhea, unintentional weight loss, and abdominal bruit. MALS is a diagnosis of exclusion, after multiple investigations. Read More

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http://dx.doi.org/10.2147/LRA.S191851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398415PMC
February 2019
6 Reads

The addition of intrathecal morphine to a transversus abdominis plane block with liposome bupivacaine provides more effective analgesia than transversus abdominis plane block with liposome bupivacaine alone: a retrospective study.

Local Reg Anesth 2019 22;12:7-13. Epub 2019 Feb 22.

Department of Anesthesiology, University of Minnesota, Minneapolis, MN, USA,

Objective: The purpose of this study was to determine if the standardization of using liposomal bupivacaine in transversus abdominis plane (LB TAP) blocks eliminated the benefit of intrathecal morphine (ITM) in patients after undergoing a cesarean section.

Methods: This was a retrospective review of 358 patients who underwent cesarean section over an 11-month period. Patients were divided into two groups: those who received only an LB TAP (67 patients) vs those who received an LB TAP and ITM (291 patients). Read More

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http://dx.doi.org/10.2147/LRA.S190225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390850PMC
February 2019
23 Reads

Effect of local anesthesia (with lidocaine vs bupivacaine) on cognitive function in patients undergoing elective cataract surgery.

Local Reg Anesth 2019 31;12:1-6. Epub 2018 Dec 31.

Department of Ophthalmology, Beni-suef University, Beni Suef, Egypt.

Purpose: Postoperative cognitive dysfunction has gained much attention over the last years. Multiple clinical trials have attempted to differentiate the effect of local vs general anesthesia on postoperative cognitive function. The aim of this work was to study the effect of local anesthesia with lidocaine vs bupivacaine on cognitive function. Read More

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http://dx.doi.org/10.2147/LRA.S185367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318706PMC
December 2018
10 Reads

Treatment of peripheral pain with low-dose local anesthetics by epidermal, epithelial and periosteal application.

Local Reg Anesth 2018 11;11:129-136. Epub 2018 Dec 11.

Graf Biostatistics, CH-8400 Winterthur, Switzerland.

Objectives: The efficiency of local anesthetics (LAs) in the treatment of peripheral pain is commonly attributed to their capacity to block the axon conduction of sensory nerves. LAs even in non-blocking concentration suppress oscillations of the resting membrane potential. Spiking in sensory neurons is triggered by subthreshold membrane potential oscillations (SMPOs), which reach threshold and is maintained by depolarizing impulse after oscillations. Read More

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http://dx.doi.org/10.2147/LRA.S151316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294063PMC
December 2018
10 Reads

Real-time ultrasound-guided retrobulbar block vs blind technique for cataract surgery (pilot study).

Local Reg Anesth 2018 6;11:123-128. Epub 2018 Dec 6.

Asiout University, Asyut, Egypt.

Background: Retrobulbar regional eye block aims to ensure eye globe akinesia and anesthesia during ophthalmic surgery, and despite the rarity of occurrence of complications due to the blind needle passage while performing either peribulbar or retrobulbar block, some of them are serious and may be life threatening.

Aim: The aim of this study was to estimate the accuracy and safety of real-time ultrasound-guided retrobulbar regional anesthesia in comparison with the blind technique for cataract surgery.

Design: This was a prospective randomized controlled trial. Read More

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http://dx.doi.org/10.2147/LRA.S178771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287535PMC
December 2018
11 Reads

Patient-controlled paravertebral analgesia for video-assisted thoracoscopic surgery lobectomy.

Local Reg Anesth 2018 22;11:115-121. Epub 2018 Nov 22.

Department of Anesthesia and Pain Medicine, Military Hospital 103, Vietnam Military Medical University, Hanoi, Vietnam,

Background: Paravertebral block has been proven to be an efficient method to provide post-thoracotomy pain management. This study aimed to compare patient-controlled paravertebral analgesia (PCPA) and intravenous patient-controlled analgesia (IVPCA) in terms of analgesic efficiency, respiratory function, and adverse effects after video-assisted thoracoscopic surgery (VATS) lobectomy.

Patients And Methods: The prospective randomized trial study was carried out on 60 patients who underwent VATS lobectomy (randomly allocated 30 patients in each group). Read More

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http://dx.doi.org/10.2147/LRA.S184589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255283PMC
November 2018
15 Reads

Broken needle during spinal anesthesia: an avoidable complication.

Local Reg Anesth 2018 23;11:111-113. Epub 2018 Nov 23.

Department of Anesthesia, Ales-en-Cévennes Hospital, Alès-en-Cévennes, France.

The occurrence of a needle breaking is a very rare complication of spinal anesthesia (SA). We report a case of a broken spinal needle occurring in a morbid obese pregnant woman during SA indicated for an emergent cesarean section. Multiple puncture attempts due to difficult identification of lumbar spine, associated with an inadequate use of the introducer, contributed to this complication. Read More

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https://www.dovepress.com/broken-needle-during-spinal-anesth
Publisher Site
http://dx.doi.org/10.2147/LRA.S175547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260186PMC
November 2018
36 Reads

Regional anesthesia to ameliorate postoperative analgesia outcomes in pediatric surgical patients: an updated systematic review of randomized controlled trials.

Local Reg Anesth 2018 15;11:91-109. Epub 2018 Nov 15.

Department of Anesthesiology, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, USA,

Regional anesthesia is becoming increasingly popular among anesthesiologists in the management of postoperative analgesia following pediatric surgery. The main objective of this review was to systematically evaluate the last 5 years of randomized controlled trials on the role of regional anesthesia techniques in alleviating postoperative pain associated with various pediatric surgical procedures. Forty studies on 2,408 pediatric patients were evaluated. Read More

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http://dx.doi.org/10.2147/LRA.S185554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244583PMC
November 2018
23 Reads

Erector spinae block for postoperative analgesia following axillary hidradenitis suppurativa resection: a case report.

Local Reg Anesth 2018 15;11:87-90. Epub 2018 Nov 15.

Department of Anesthesiology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX 77030, USA,

Hidradenitis suppurativa (HS) is a chronic inflammatory disease of the terminal hair follicle of the apocrine gland-bearing skin, presenting with inflamed nodules, abscesses, and sinus tracts. Autoimmune, genetic, and infectious factors have been implicated in its pathogenesis. HS can be managed medically using topical and systemic antibiotics and with tumor necrosis factor antibody therapy in severe cases. Read More

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http://dx.doi.org/10.2147/LRA.S179830DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244584PMC
November 2018
11 Reads

Impact of thoracic epidural sympathetic block on cardiac repolarization.

Local Reg Anesth 2018 16;11:81-85. Epub 2018 Oct 16.

Department of Anesthesiology, Dokkyo Medical University, school of Medicine, Mibu, Tochigi 321-0293, Japan,

Purpose: The interval from the peak to the end of the T wave (Tp-Te) on electrocardiography is considered a marker of ventricular arrhythmias. A previous study suggested that right stellate ganglion block prolonged QT and QT dispersion (QTD). We investigated the effect of thoracic epidural sympathetic block with 1% mepivacaine on QT, QTD, Tp-Te, and Tp-Te/QT by using computerized measurement. Read More

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http://dx.doi.org/10.2147/LRA.S182402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200079PMC
October 2018
35 Reads

Caudal epidural block instead of general anesthesia in an adult with Duchenne muscular dystrophy.

Local Reg Anesth 2018 15;11:75-80. Epub 2018 Oct 15.

Department of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, OH, USA,

Duchenne muscular dystrophy (DMD), first described in 1834, is an X-linked dystrophinopathy, leading to early onset skeletal muscle weakness. Life expectancy is reduced to early adulthood as a result of involvement of voluntary skeletal muscles with respiratory failure, orthopedic deformities, and associated cardiomyopathy. Given its multisystem involvement, surgical intervention may be required to address the sequelae of the disease process. Read More

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https://www.dovepress.com/caudal-epidural-block-instead-of-g
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http://dx.doi.org/10.2147/LRA.S180867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197695PMC
October 2018
29 Reads

Frailty and anesthesia - risks during and post-surgery.

Local Reg Anesth 2018 5;11:61-73. Epub 2018 Oct 5.

Centre for Research in Geriatric Medicine, University of Queensland, Princess Alexandra Hospital, Brisbane, QLD, Australia,

Frailty is a state of decreased physiologic reserve and resistance to stressors. Its prevalence increases with age and is estimated to be 26% in those aged above 85 years. As the population ages, frailty will be increasingly seen in surgical patients receiving anesthesia. Read More

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https://www.dovepress.com/frailty-and-anesthesia-risks-durin
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http://dx.doi.org/10.2147/LRA.S142996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178933PMC
October 2018
54 Reads

Plasma ropivacaine concentration after TAP block in a patient with cardiac and renal failure.

Local Reg Anesth 2018 21;11:57-60. Epub 2018 Sep 21.

Department of Anesthesiology and Resuscitology, Shinshu University School of Medicine, Matsumoto, Nagano, Japan,

We report a successful ultrasound-guided transversus abdominis plane (TAP) block as an analgesic option for minor abdominal surgery in a 66-year-old patient with cardiac, respiratory, and renal dysfunction caused by primary systemic amyloidosis. Bilateral TAP blocks with 120 mg (1.8 mg/kg) of ropivacaine provided sufficient intra- and postoperative analgesia for insertion of a continuous ambulatory peritoneal dialysis catheter. Read More

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https://www.dovepress.com/plasma-ropivacaine-concentration-a
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http://dx.doi.org/10.2147/LRA.S173877DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159791PMC
September 2018
18 Reads

The impact of fluoroscopic confirmation of thoracic imaging on accuracy of thoracic epidural catheter placement on postoperative pain control.

Local Reg Anesth 2018 29;11:49-56. Epub 2018 Aug 29.

Department of Anesthesiology, Advocate Illinois Masonic Medical Center, Chicago, IL, USA,

Background: Thoracic epidural analgesia (TEA) provides superior postoperative pain control compared to parenteral opioids after major thoracic and abdominal surgeries. However, some studies with respect to benefits of continuous TEA have shown mixed results. The purpose of this study was to determine the rate of successful TEA catheter insertion into the epidural space using contrast fluoroscopy and the impact of placement location on postoperative analgesia and opioid use. Read More

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https://www.dovepress.com/the-impact-of-fluoroscopic-confirm
Publisher Site
http://dx.doi.org/10.2147/LRA.S155984DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120568PMC
August 2018
14 Reads

Foot drop after spinal anesthesia for cesarean section: a case report.

Local Reg Anesth 2018 10;11:45-47. Epub 2018 Aug 10.

Lung Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran,

Objective: Spinal anesthesia is the preferred anesthetic technique for cesarean section. Neurological complications are very rare and often transient after spinal anesthesia.

Case Report: In the present case, a 37-year-old woman was considered eligible for cesarean section due to fetal distress. Read More

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http://dx.doi.org/10.2147/LRA.S165587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089110PMC
August 2018
44 Reads

Local anesthetic systemic toxicity: current perspectives.

Local Reg Anesth 2018 8;11:35-44. Epub 2018 Aug 8.

Department of Anesthesia, Toronto Western Hospital, University of Toronto, Ontario, Canada.

Local anesthetic systemic toxicity (LAST) is a life-threatening adverse event that may occur after the administration of local anesthetic drugs through a variety of routes. Increasing use of local anesthetic techniques in various healthcare settings makes contemporary understanding of LAST highly relevant. Recent data have demonstrated that the underlying mechanisms of LAST are multifactorial, with diverse cellular effects in the central nervous system and cardiovascular system. Read More

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http://dx.doi.org/10.2147/LRA.S154512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6087022PMC
August 2018
69 Reads

Optimizing the securement of epidural catheters: an in vitro trial.

Local Reg Anesth 2018 17;11:31-34. Epub 2018 Jul 17.

Department of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, OH, USA,

Introduction: Epidural anesthesia is frequently used to provide postoperative analgesia following major surgical procedures. Secure fixation of the epidural catheter is necessary to prevent premature dislodgment and loss of epidural analgesia. Using an in vitro model, the current prospective study evaluates different types of dressings for securement of an epidural catheter by quantifying the force in Newtons (N) required for dislodgment using a digital force gage. Read More

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http://dx.doi.org/10.2147/LRA.S172799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054289PMC
July 2018
29 Reads

Deterioration of Regional Lung Strain and Inflammation during Early Lung Injury.

Am J Respir Crit Care Med 2018 10;198(7):891-902

1 Department of Anesthesia, Critical Care and Pain Medicine.

Rationale: The contribution of aeration heterogeneity to lung injury during early mechanical ventilation of uninjured lungs is unknown.

Objectives: To test the hypotheses that a strategy consistent with clinical practice does not protect from worsening in lung strains during the first 24 hours of ventilation of initially normal lungs exposed to mild systemic endotoxemia in supine versus prone position, and that local neutrophilic inflammation is associated with local strain and blood volume at global strains below a proposed injurious threshold.

Methods: Voxel-level aeration and tidal strain were assessed by computed tomography in sheep ventilated with low Vt and positive end-expiratory pressure while receiving intravenous endotoxin. Read More

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http://dx.doi.org/10.1164/rccm.201710-2038OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173064PMC
October 2018
19 Reads

Spinal anesthesia instead of general anesthesia for infants undergoing tendon Achilles lengthening.

Local Reg Anesth 2018 3;11:25-29. Epub 2018 May 3.

Department of Anesthesiology & Pain Medicine, Nationwide Children's Hospital, Columbus, OH, USA.

Spinal anesthesia (SA) has been used relatively sparingly in the pediatric population, as it is typically reserved for patients in whom the perceived risk of general anesthesia is high due to comorbid conditions. Recently, concern has been expressed regarding the potential long-term neurocognitive effects of general anesthesia during the early stages of life. In view of this, our center has developed a program in which SA may be used as the sole agent for applicable surgical procedures. Read More

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http://dx.doi.org/10.2147/LRA.S157650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937509PMC
May 2018
12 Reads

Pectoral I Block Does Not Improve Postoperative Analgesia After Breast Cancer Surgery: A Randomized, Double-Blind, Dual-Centered Controlled Trial.

Reg Anesth Pain Med 2018 Aug;43(6):596-604

Department of Anesthesiology, Centre Hospitalier de l'Université de Montréal, Montréal.

Background And Objectives: General anesthesia for breast surgery may be supplemented by using a regional anesthetic technique. We evaluated the efficacy of the first pectoral nerve block (Pecs I) in treating postoperative pain after breast cancer surgery.

Methods: A randomized, double-blind, dual-centered, placebo-controlled trial was performed. Read More

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https://rapm.bmj.com/lookup/doi/10.1097/AAP.0000000000000779
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http://dx.doi.org/10.1097/AAP.0000000000000779DOI Listing
August 2018
37 Reads

Remifentanil-induced postoperative hyperalgesia: current perspectives on mechanisms and therapeutic strategies.

Local Reg Anesth 2018 9;11:15-23. Epub 2018 Apr 9.

Department of Anesthesia and Intensive Care, IRCCS-ISMETT (Istituto Mediterraneo per i Trapianti e Terapie ad alta specializzazione), Palermo, Italy.

The use of remifentanil in clinical practice offers several advantages and it is used for a wide range of procedures, ranging from day-surgery anesthesia to more complex procedures. Nonetheless, remifentanil has been consistently linked with development of opioid-induced hyperalgesia (OIH), which is described as a paradoxical increase in sensitivity to painful stimuli that develops after exposure to opioid treatment. The development of OIH may cause several issues, delaying recovery after surgery and preventing timely patient's discharge. Read More

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http://dx.doi.org/10.2147/LRA.S143618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898588PMC
April 2018
12 Reads

Effect of warming anesthetic on pain perception during dental injection: a split-mouth randomized clinical trial.

Local Reg Anesth 2018 22;11:9-13. Epub 2018 Feb 22.

Department of Center for Interdisciplinary Studies on Nervous System (CISNe), Universidad Austral de Chile, Valdivia, Chile.

Background: The purpose of this study is to determine the effectiveness of warming anesthesia on the control of the pain produced during the administration of dental anesthesia injection and to analyze the role of Transient Receptor Potential Vanilloid-1 nociceptor channels in this effect.

Patients And Methods: A double-blind, split-mouth randomized clinical trial was designed. Seventy-two volunteer students (22. Read More

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http://dx.doi.org/10.2147/LRA.S147288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826251PMC
February 2018
15 Reads

Local anesthetics for brain tumor resection: current perspectives.

Local Reg Anesth 2018 1;11:1-8. Epub 2018 Feb 1.

Department of Anesthesiology, Erasmus MC, Rotterdam, The Netherlands.

This review summarizes the added value of local anesthetics in patients undergoing craniotomy for brain tumor resection, which is a procedure that is carried out frequently in neurosurgical practice. The procedure can be carried out under general anesthesia, sedation with local anesthesia or under local anesthesia only. Literature shows a large variation in the postoperative pain intensity ranging from no postoperative analgesia requirement in two-thirds of the patients up to a rate of 96% of the patients suffering from severe postoperative pain. Read More

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http://dx.doi.org/10.2147/LRA.S135413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798542PMC
February 2018
16 Reads

Esophageal Manometry and Regional Transpulmonary Pressure in Lung Injury.

Am J Respir Crit Care Med 2018 04;197(8):1018-1026

2 Translational Medicine, Departments of Critical Care Medicine and Anesthesia, Hospital for Sick Children, and.

Rationale: Esophageal manometry is the clinically available method to estimate pleural pressure, thus enabling calculation of transpulmonary pressure (Pl). However, many concerns make it uncertain in which lung region esophageal manometry reflects local Pl.

Objectives: To determine the accuracy of esophageal pressure (Pes) and in which regions esophageal manometry reflects pleural pressure (Ppl) and Pl; to assess whether lung stress in nondependent regions can be estimated at end-inspiration from Pl. Read More

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http://dx.doi.org/10.1164/rccm.201709-1806OCDOI Listing
April 2018
43 Reads