571,709 results match your criteria Little League Elbow Syndrome


MEASUREMENT OF EMF EXPOSURE AROUND SMALL CELL BASE STATION SITES.

Radiat Prot Dosimetry 2018 Nov 29. Epub 2018 Nov 29.

Alphawave, 3 Meson Street, Technopark, Stellenbosch, South Africa.

As mobile network technologies and usage change, mobile network cells have become smaller to meet the increased demand for data throughput. Small cell base stations are frequently used as a mobile network deployment method and are predominantly installed to service areas with a high density of people and to cover a small geographical area. Various measurement programs of the electromagnetic field (EMF) exposure have been conducted around base stations in general and these results have been published. Read More

View Article
November 2018

Plasmid-based gap-repair recombineered transgenes reveal a central role for introns in mutually exclusive alternative splicing in Down Syndrome Cell Adhesion Molecule exon 4.

Nucleic Acids Res 2018 Dec 12. Epub 2018 Dec 12.

School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.

Alternative splicing is a key feature of human genes, yet studying its regulation is often complicated by large introns. The Down Syndrome Cell Adhesion Molecule (Dscam) gene from Drosophila is one of the most complex genes generating vast molecular diversity by mutually exclusive alternative splicing. To resolve how alternative splicing in Dscam is regulated, we first developed plasmid-based UAS reporter genes for the Dscam variable exon 4 cluster and show that its alternative splicing is recapitulated by GAL4-mediated expression in neurons. Read More

View Article
December 2018

Health Burden, Instrumental and Emotional Support Adequacy, and Depressive Symptoms in Older Men With HIV.

Gerontologist 2018 Dec 12. Epub 2018 Dec 12.

Virginia Tech Center for Gerontology, Virginia Polytechnic Institute and State University, Blacksburg.

Background And Objectives: Older adults with HIV face greater health burden than HIV-uninfected counterparts. Little is known about resources that might mediate the influence of physiological health burden on psychological well-being. Informed by the stress process model, we assessed the influence of multifaceted health burden indicators on depressive symptoms and evaluated the mediating effects of social support adequacy. Read More

View Article
December 2018

Associations between general practice characteristics with use of urgent referrals for suspected cancer and endoscopies: a cross-sectional ecological study.

Fam Pract 2018 Dec 12. Epub 2018 Dec 12.

The Health Improvement Institute (THIS), University of Cambridge, Cambridge, UK.

Background: Large variation in measures of diagnostic activity has been described previously between English general practices, but related predictors remain understudied.

Objective: To examine associations between general practice population and characteristics, with the use of urgent referrals for suspected cancer, and use of endoscopy.

Methods: Cross-sectional observational study of English general practices. Read More

View Article
December 2018

Functionally distinct assembly of vascular plants colonizing alpine cushions suggests their vulnerability to climate change.

Ann Bot 2018 Dec 12. Epub 2018 Dec 12.

Institute of Botany, The Czech Academy of Sciences, Průhonice, Czech Republic.

Background And Aims: Alpine cushion plants can initially facilitate other species during ecological succession, but later on can be negatively affected by their development, especially when beneficiaries possess traits allowing them to overrun their host. This can be reinforced by accelerated warming favouring competitively strong species over cold-adapted cushion specialists. However, little empirical research has addressed the trait-based mechanisms of these interactions. Read More

View Article
December 2018

TNM classification of malignant tumors (Breast Cancer Study Group).

Jpn J Clin Oncol 2018 Dec 12. Epub 2018 Dec 12.

Department of Breast Oncology, Aichi Cancer Center Hospital, Nagoya, Japan.

The eighth editions of the primary tumor, lymph node and metastasis classifications for breast cancer issued by the American Joint Commission of Cancer and the Union for International Cancer Control were revised in 2017. The major change made by the American Joint Commission of Cancer is to incorporate biological factors such as estrogen and progesterone receptor, human epidermal growth factor receptor 2, histological grade and multigene prognostic assays, into the staging system. Tumor biomarkers and low recurrence scores confirmed by multigene prognostic assays change the staging. Read More

View Article
December 2018

The antiviral mechanism of viperin and its splice variant in spring viremia of carp virus infected fathead minnow cells.

Fish Shellfish Immunol 2018 Dec 9. Epub 2018 Dec 9.

College of Fisheries, Huazhong Agricultural University, Wuhan, 430070, China; Freshwater Aquaculture Collaborative Innovation Center of Hubei Province, Wuhan, 430070, China; Hubei Engineering Technology Research Center for Aquatic Animal Diseases Control and Prevention, Wuhan, 430070, China. Electronic address:

Viperin is known to play an important role in innate immune and its antiviral mechanisms are well demonstrated in mammals. Fish Viperin mediates antiviral activity against several viruses. However, little has been done to the underlying mechanism. Read More

View Article
December 2018

Revision of Failed Resurfacing Hemiarthroplasty: Midterm Results, Survival, and Group Comparison.

Orthopedics 2018 Dec 11:1-7. Epub 2018 Dec 11.

Shoulder arthroplasty is a valuable option for treating glenohumeral osteoarthritis. Revision surgery for a failed shoulder arthroplasty is associated with difficult procedures, complications, and worse outcomes. Compared with a total joint arthroplasty, a resurfacing prosthesis has the supposed advantages of limited perioperative complications and little bone loss during revision. Read More

View Article
December 2018

Changes of sexual risk behaviors and sexual connections among HIV-positive men who have sex with men along their HIV care continuum.

PLoS One 2018 12;13(12):e0209008. Epub 2018 Dec 12.

Stanley Ho Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Hong Kong.

Background: While HIV incidence among men who have sex with men (MSM) is increasing in Hong Kong, unprotected sex apparently remains prevalent among those infected but virally non-suppressed. Little is known about how sexual behaviours and sexual connections may change among MSM along their HIV care continuum.

Methods: In this retrospective cross-sectional study, HIV-positive MSM attending the largest HIV specialist clinic in Hong Kong between October and December 2014 were invited to complete a self-administrated structured questionnaire. Read More

View Article
December 2018

Validation of a single factor representing the indicators of metabolic syndrome as a continuous measure of metabolic load and its association with health and cognitive function.

PLoS One 2018 12;13(12):e0208231. Epub 2018 Dec 12.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Lipid Clinic at the Interdisciplinary Metabolism Center, Berlin, Germany.

The metabolic syndrome (MetS) is a cluster of risk factors for cardiovascular disease associated with reduced physical fitness, higher disease burden, and impaired cognitive functions. Little is known about the operation of these risk factors in older adults when considered comprehensively without relying on the cut-off values of the single MetS components. The three main aims of the current study were to: (i) establish a latent metabolic load factor (MetL), using confirmatory factor analysis (CFA), and representing a continuous measure of MetL, defined by indicators that are commonly used to separate MetS groups from healthy individuals; (ii) examine the associations of this MetL factor with objective health, and cognitive function in men and women; (iii) compare the magnitude of these associations to those observed for the individual indicators used to define the MetL factor as well to the classical categorized MetS vs. Read More

View Article
December 2018

Engaging community leaders to improve male partner participation in the prevention of mother-to-child transmission of HIV in Dar es Salaam, Tanzania.

PLoS One 2018 12;13(12):e0207986. Epub 2018 Dec 12.

Department of Public Health Sciences, Global Health (IHCAR), Karolinska Institutet, Stockholm, Sweden.

Background: Male partner participation improves uptake, retention and outcomes of prevention of mother-to-child transmission of HIV (PMTCT) services. However, in patriarchal settings few men accompany their partners to antenatal care (ANC) and PMTCT services. We explored whether community leaders can improve male partner participation in ANC and PMTCT. Read More

View Article
December 2018

Regional paleoclimates and local consequences: Integrating GIS analysis of diachronic settlement patterns and process-based agroecosystem modeling of potential agricultural productivity in Provence (France).

PLoS One 2018 12;13(12):e0207622. Epub 2018 Dec 12.

Schools of Sustainability and Human Evolution and Social Change, Arizona State University, Tempe, Arizona, United States of America.

Holocene climate variability in the Mediterranean Basin is often cited as a potential driver of societal change, but the mechanisms of this putative influence are generally little explored. In this paper we integrate two tools-agro-ecosystem modeling of potential agricultural yields and spatial analysis of archaeological settlement pattern data-in order to examine the human consequences of past climatic changes. Focusing on a case study in Provence (France), we adapt an agro-ecosystem model to the modeling of potential agricultural productivity during the Holocene. Read More

View Article
December 2018

Chimpanzees' understanding of social leverage.

PLoS One 2018 12;13(12):e0207868. Epub 2018 Dec 12.

Department of Developmental and Comparative Psychology, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.

Social primates can influence others through the control of resources. For instance, dominant male chimpanzees might allow subordinates access to mate with females in exchange for social support. However, little is known about how chimpanzees strategically use a position of leverage to maximize their own benefits. Read More

View Article
December 2018

Characterization of Brain Signatures to Add Precision to Self-Management Health Information Interventions.

Nurs Res 2018 Dec 12. Epub 2018 Dec 12.

Edward J. and Louise Mellen Professor of Nursing, Case Western Reserve University, Cleveland, OH Marvin E. and Ruth Durr Denekas Professor of Nursing, Case Western Reserve University, Cleveland, OH Associate Professor, Case Western Reserve University, Cleveland, OH PhD Student, Case Western Reserve University, Cleveland, OH Professor, Kent State University, Kent, OH Assistant Professor, Case Western Reserve University, Cleveland, OH Assistant Professor, Chief Diversity Officer, The Ohio State University, Columbus, OH Associate Professor, Case Western Reserve University, Cleveland, OH Associate Professor, Case Western Reserve University, Cleveland, OH.

Background: Although many of the proposed mediating processes of self-management interventions are operationally defined as cognitive processes (e.g., acquiring and using information, self-efficacy, motivation, decision-making), little is known about their underlying brain mechanisms. Read More

View Article
December 2018

Application of the ConNECT Framework to Precision Health and Health Disparities.

Nurs Res 2018 Dec 12. Epub 2018 Dec 12.

Professor and Associate Vice Dean of Research, University of South Florida College of Nursing, Tampa, FL Founding Director, Center of Community Alliance for Research Education, Professor, Department of Population Sciences, Beckman Research Institute, City of Hope Medical Center, Duarte, CA Associate Professor, The Ohio State University, College of Nursing, Columbus, OH Department of Health Outcomes and Behavior, Division of Population Science, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612 Assistant Professor, College of Nursing, University of Utah, Salt Lake City, UT Professor, Department of Psychological Science, University of North Carolina at Charlotte, Charlotte, NC Senior Member, Division of Population Science, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL Department of Health Disparities Research, MD Anderson Cancer Center, Houston, TX Division of Population Science, H. Lee Moffitt Cancer Center and Research Institute & Department of Oncological Sciences, University of South Florida, College of Medicine, Tampa, FL Assistant Professor, Department of Oncology Sciences, Icahn School of Medicine at Mount Sinai, New York, NY Assistant Professor, Department of Community Health Sciences, Boston University School of Public Health and Department of Social and Behavioral Sciences, and Harvard T.H. Chan School of Public Health, Boston, MA Assistant Professor, Department of Medical Social Sciences and Robert H. Lurie Comprehensive Cancer Center at Northwestern University Feinberg School of Medicine, Chicago, IL Associate Professor, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR Staff Scientist, Project Director, Biobehavioral Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA Strategic Director of Health Disparities Research, Behavioral Research Center, American Cancer Society, Atlanta, GA.

Background: An emphasis on precision health (PH) has stimulated precision medicine studies to focus on the interplay of biological, behavioral, and environmental factors with disease risks, treatments, prognoses, and outcomes affecting health disparities. It is imperative, as well, that improving health equity among underserved populations remains central to the efforts and aims of PH.

Objectives: Apply the transdisciplinary ConNECT Framework: A model for advancing behavioral medicine science and practice to foster health equity to PH by integrating a population health agenda for reducing health disparities. Read More

View Article
December 2018

Long-term Outcomes of Ossiculoplasty With and Without an Intact Malleus.

Otol Neurotol 2019 Jan;40(1):73-78

Division of Otology and Neurotology, Department of Otolaryngology-Head and Neck Surgery, University of Arkansas for Medical Sciences, Little Rock, Arkansas.

Objective: To compare long-term hearing outcomes following ossiculoplasty with cartilage tympanoplasty with (M) and without (M) the malleus present.

Study Design: Retrospective chart review.

Setting: Tertiary referral center. Read More

View Article
January 2019

Salivary Biomarkers of Parenting Stress in Mothers Under Community Criminal Justice Supervision.

Nurs Res 2019 Jan/Feb;68(1):48-56

Jenna K. Rieder, BA, is Research Assistant, The Graduate Center, The City University of New York, NY. Lorie S. Goshin, PhD, RN, is Assistant Professor; and D.R. Gina Sissoko, BA, is Research Assistant, Hunter College, The City University of New York, NY. Olena Kleshchova, MS, is Research Assistant, The Graduate Center, The City University of New York, NY. Mariann R. Weierich, PhD, is Associate Professor, Hunter College, The City University of New York, NY.

Background: Community criminal justice supervised mothers are an underserved population who experience high rates of psychological distress and unique parenting challenges, but little is known about physiological stress system function in this population.

Objective: We tested the salivary biomarkers of the sympathetic nervous system (SNS) and hypothalamic-pituitary-adrenal (HPA) axis function as predictors of subjective maternal stress.

Method: We recruited 23 mothers (age: M = 35. Read More

View Article
December 2018

The Titration and Tolerability of Sacubitril/Valsartan for Patients with Heart Failure in Clinical Practice.

J Cardiovasc Pharmacol 2018 Dec 10. Epub 2018 Dec 10.

University of Alberta, Edmonton, Canada.

Little is known about the dosing and tolerability of sacubitril/valsartan (LCZ696; Entresto™, Quebec, Canada) in a non-clinical trial population. This study was conducted to evaluate the use and tolerability of sacubitril/valsartan in patients followed at a multidisciplinary heart failure clinic. We performed a retrospective chart review of 126 patients with heart failure, initiated on sacubitril/valsartan, and seen at a specialty heart failure clinic between August 1, 2015 and August 1, 2017. Read More

View Article
December 2018

LongShengZhi capsule reduces established atherosclerotic lesions in apoE deficient mice by ameliorating hepatic lipid metabolism and inhibiting inflammation.

J Cardiovasc Pharmacol 2018 Dec 10. Epub 2018 Dec 10.

College of Biomedical Engineering, Hefei University of Technology, Hefei, China.

Disorders of lipid metabolism and inflammation play an important role in atherosclerosis. LongShengZhi capsule (LSZ), a Chinese herbal medicine, has been used for treatment of patients with vascular diseases for many years. Herein, we determined the effect of LSZ on the progression of established atherosclerotic lesions in apoE deficient (apoE) mice. Read More

View Article
December 2018

Development and Usability Testing of the Society for Pediatric Anesthesia Pedi Crisis Mobile Application.

Anesth Analg 2018 Dec 11. Epub 2018 Dec 11.

United States National Aeronautics and Space Administration, Ames Research Center, Moffett Field, California.

When life-threatening, critical events occur in the operating room, the fast-paced, high-distraction atmosphere often leaves little time to think or deliberate about management options. Success depends on applying a team approach to quickly implement well-rehearsed, systematic, evidence-based assessment and treatment protocols. Mobile devices offer resources for readily accessible, easily updatable information that can be invaluable during perioperative critical events. Read More

View Article
December 2018

mTOR, glycotoxins and the parallel universe.

Authors:
Alan S Green

Aging (Albany NY) 2018 Dec 12. Epub 2018 Dec 12.

The Medical Practice of Dr. Alan S. Green, Little Neck, NY 11363, USA.

View Article
December 2018

Population differentiation within Anisogramma anomala in North America.

Phytopathology 2018 Dec 12. Epub 2018 Dec 12.

Rutgers The State University of New Jersey, 242612, Department of Plant Biology, New Brunswick, New Jersey, United States ;

Anisogramma anomala (Peck) E. Müller, a biotrophic ascomycete in the order Diaporthales, causes eastern filbert blight (EFB) of hazelnuts (Corylus). Until recently, little has been documented on its genetic diversity and population structure. Read More

View Article
December 2018

Perceptions of a Good Death in Children with Life-Shortening Conditions: An Integrative Review.

J Palliat Med 2018 Dec 11. Epub 2018 Dec 11.

2 International Observatory on End of Life Care, Lancaster University , Lancaster, United Kingdom .

Background: For children with life-shortening illness, achieving a "good death" can be a tacit goal. There is little understanding of how different stakeholders perceive what a "good death" might be.

Objective: To review empirical literature to construct an understanding of a "good death" for children with life-shortening conditions. Read More

View Article
December 2018

Differential developmental changes in cortical representations of auditory-vocal stimuli in songbirds.

J Neurophysiol 2018 Dec 12. Epub 2018 Dec 12.

University of Southern California, United States.

Procedural skill learning requires iterative comparisons between feedback of self-generated motor output and a goal sensorimotor pattern. In juvenile songbirds, neural representations of both self-generated behaviors (each bird's own immature song) and the goal motor pattern (each bird's adult tutor song) are essential for vocal learning, yet little is known about how these behaviorally relevant stimuli are encoded. We made extracellular recordings during song playback in anesthetized juvenile and adult zebra finches ( Taeniopygia guttata) in adjacent cortical regions RA (robust nucleus of the arcopallium), AId (dorsal intermediate arcopallium), and RA-cup, each of which is well-situated to integrate auditory-vocal information: RA is a motor cortical region that drives vocal output, AId is an adjoining cortical region whose projections converge with basal ganglia loops for song learning in the dorsal thalamus, and RA-cup surrounds RA and receives inputs from primary and secondary auditory cortex. Read More

View Article
December 2018

Cdc42 negatively regulates endocytosis during apical membrane maintenance in live animals.

Mol Biol Cell 2018 Dec 12:mbcE18100615. Epub 2018 Dec 12.

Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 37 Convent Dr. Rm 2050B, Bethesda, MD, 20892 USA.

Lumen establishment and maintenance are fundamental for tubular organs physiological functions. Most of the studies investigating the mechanisms regulating this process have been carried out in cell cultures or in smaller organisms, whereas little has been done in mammalian model systems in vivo. Here we used the salivary glands of live mice to examine the role of the small GTPase Cdc42 in the regulation of the homeostasis of the intercellular canaliculi, a specialized apical domain of the acinar cells, where protein and fluid secretion occur. Read More

View Article
December 2018

Interindividual Variation in Low-Density Lipoprotein Cholesterol Level Reduction With Evolocumab: An Analysis of FOURIER Trial Data.

JAMA Cardiol 2018 Dec 12. Epub 2018 Dec 12.

Thrombolysis in Myocardial Infarction (TIMI) Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

Importance: Little is known about the heterogeneity in low-density lipoprotein cholesterol levels (LDL-C) lowering with proprotein convertase subtilisin kexin 9 (PCSK9) inhibitor medications.

Objective: To evaluate the interindividual variability in LDL-C reduction with the PCSK9 inhibitor drug evolocumab.

Design, Setting, And Participants: We examined the percentage change in LDL-C levels from baseline in the Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk (FOURIER) trial, a placebo-controlled randomized clinical trial of the PCSK9 inhibitor evolocumab in patients with stable atherosclerotic cardiovascular disease who were taking statin medications. Read More

View Article
December 2018

Beyond reasonable drought: hotspots reveal a link between the 'Big Dry' and cryptosporidiosis in Australia's Murray Darling Basin.

J Water Health 2018 Dec;16(6):1033-1037

National Centre for Geographic and Resource Analysis in Primary Health Care, Australian National University, Canberra, 2600, Australia.

There is little evidence on how the health impacts of drought vary spatially and temporally. With a focus on waterborne cryptosporidiosis, we identify spatio-temporal hotspots and by using interrupted time series analysis, examine the impact of Australia's Big Dry (2001-2009) in these disease clusters in the Murray Darling Drainage Basin. Analyses revealed a statistically significant hotspot in the north of the Australian Capital Territory (ACT) and a hotspot in the north-eastern end of the basin in Queensland. Read More

View Article
December 2018

Critical elements for local Indigenous water security in Canada: a narrative review.

J Water Health 2018 Dec;16(6):893-903

School of Environmental Studies, Queen's University, Kingston, Canada E-mail: Public Health Ontario, Kingston, Canada.

Indigenous communities in Canada are over-represented with respect to poor water quality and water advisories. To date, approaches to solve this water crisis have been founded in the Western Science (WS) context with little to no consultation or dialogue with those communities most impacted, and without regard for culture. A literature review was undertaken to: (i) document Indigenous Knowledge (IK), and perspectives regarding water and (ii) to identify current local water security tools utilized by Indigenous communities. Read More

View Article
December 2018

[Leisure among university students in the healthcare area: a review of the literature].

Cien Saude Colet 2018 Dec;23(12):4221-4229

Faculdade de Medicina, Universidade Estadual Paulista Julio de Mesquita Filho. Rubião Junior s/n, Rubião Junior. 18618-000 Botucatu SP Brasil.

This article set out to analyze studies on leisure activities among university students in the healthcare area. It conducted a search using the following key words: leisure and students, and their corresponding terms in Spanish and English in the Bireme database, which resulted in 32 articles at the end of the review. In the articles analyzed there was a predominance of the following leisure interests: sports, social, intellectual and artistic activities, with a greater number of articles presenting experiences in sports. Read More

View Article
December 2018

Malignant solitary fibrous tumor of the kidney with liver metastasis: A case report and literature review.

J Cancer Res Ther 2018 Dec;14(Supplement):S1217-S1219

Department of Medical Imaging, Shanghai Gongli Hospital, Shanghai 200135, China.

Solitary fibrous tumor (SFT) is a rare spindle cell soft tissue tumor which is rarely encountered in the clinical setting and imaging findings are nonspecific, mainly occurring in the tissue structure of the serosa. However, there is very little report on SFT originating in the kidney in the medical literature. We report a case of SFT with liver metastasis in an adult female and discuss the pathological features as it appears in our case. Read More

View Article
December 2018

People With Advanced Cancer: The Process of Living Well With Awareness of Dying.

Qual Health Res 2018 Dec 12:1049732318816298. Epub 2018 Dec 12.

1 Universidad de Navarra, ICS, Grupo ATLANTES, Pamplona, Spain.

Literature suggests that it is possible to live well with advanced cancer but little is known about the process. In this article, we present a secondary analysis of experiences of living with advanced cancer ( n = 22) that refines the theory of "Living Well with Chronic Illness" for a different context and population. The refined theory explains the experience of living well with advanced cancer illuminating a five-phase iterative process: struggling, accepting, living with advanced cancer, sharing the illness experience, and reconstructing life. Read More

View Article
December 2018

Antifouling activity of portimine, select semisynthetic analogues, and other microalga-derived spirocyclic imines.

Biofouling 2018 Dec 12:1-12. Epub 2018 Dec 12.

a Cawthron Institute , Nelson , New Zealand.

A range of natural products from marine invertebrates, bacteria and fungi have been assessed as leads for nature-inspired antifouling (AF) biocides, but little attention has been paid to microalgal-derived compounds. This study assessed the AF activity of the spirocyclic imine portimine (1), which is produced by the benthic mat-forming dinoflagellate Vulcanodinium rugosum. Portimine displayed potent AF activity in a panel of four macrofouling bioassays (EC 0. Read More

View Article
December 2018

More Income for Male Physicians; Findings About Salary Differences Between Male and Female Iranian Physicians

Balkan Med J 2018 12 12. Epub 2018 Dec 12.

Health Management Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran

Background: In recent decades, the role of women in the organizations of developed and less developed countries has increased, but little is known about gender gap in salaries of Iranian physicians.

Aims: The aim of this study was to analyze the gender gap in the salary of physicians working in public health sector of Iran and its predicting factors in 2016.

Study Design: This is a cross sectional study conducted on physicians’ salary in Iran in 2016. Read More

View Article
December 2018

[The “alcohol and pregnancy” link in training in nursing or social work: A topic to reconsider?]

Rech Soins Infirm 2018 09(134):16-32

Alcohol consumption by pregnant women and its related dangers have been a major concern for public authorities for almost twenty years. Students finishing their training in nursing or social work are only slightly over twenty themselves. The job they are soon going to practice, as a graduate nurse, social worker, financial and family counsellor, or a specialized teacher, can lead them to come into contact with pregnant alcohol-drinking women. Read More

View Article
September 2018

High-Resolution Mapping of N -Methyladenosine Using mA Crosslinking Immunoprecipitation Sequencing (mA-CLIP-Seq).

Methods Mol Biol 2019 ;1870:69-79

Department of Chemistry and Institute for Biophysical Dynamics; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA.

N -Methyladenosine, an abundant chemical modification in mRNA, plays crucial roles in regulating gene expression and biological processes. Research on mA and its functions has progressed rapidly in the past few years, aided substantially by advances in high-throughput sequencing-based methods to profile mA along the transcriptome. We present here a protocol for mA crosslinking immunoprecipitation sequencing (mA-CLIP-seq), which profiles mA on mRNA at high resolution from as little as 1 μg of poly(A)-selected mRNA. Read More

View Article
January 2019

Effects of multiple environmental factors on elimination of fenvalerate and its cis-trans isomers in aquaculture water.

Environ Sci Pollut Res Int 2018 Dec 11. Epub 2018 Dec 11.

Wuxi Fisheries College, Nanjing Agricultural University, Wuxi, People's Republic of China.

Fenvalerate (FV) is widely used in aquaculture because of their broad spectrums and high efficiency. However, little is known regarding the elimination of FV influenced by environment factors in aquaculture water, especially its cis-trans isomers (cis-FV and trans-FV). In the present study, factors influencing the aquaculture environment (open type, temperature, pH and light) were selected, and the elimination dynamics of FV and its cis-trans isomers in aquaculture water using orthogonal experiments were investigated. Read More

View Article
December 2018

"All the ward's a stage": a qualitative study of the experience of direct observation of handoffs.

Adv Health Sci Educ Theory Pract 2018 Dec 11. Epub 2018 Dec 11.

The Hospital for Sick Children, Toronto, ON, Canada.

Direct observation of clinical skills is central to assessment in a competency-based medical education model, yet little is known about how direct observation is experienced by trainees and observers. The objective of the study is to explore how direct observation was experienced by residents and faculty in the context of the I-PASS Handoff Study. In this multi-center qualitative study, we conducted focus groups and semi-structured interviews of residents and faculty members at eight tertiary pediatric centers in North America that implemented the I-PASS Handoff Bundle. Read More

View Article
December 2018

What is a cognitive map? Unravelling its mystery using robots.

Cogn Process 2018 Dec 11. Epub 2018 Dec 11.

Centre for Artificial Intelligence Research, Auckland University of Technology, Auckland, New Zealand.

Despite years of research into cognitive mapping, the process remains controversial and little understood. A computational theory of cognitive mapping is needed, but developing it is difficult due to the lack of a clear interpretation of the empirical findings. For example, without knowing what a cognitive map is or how landmarks are defined, how does one develop a computational theory for it? We thus face the conundrum of trying to develop a theory without knowing what is computed. Read More

View Article
December 2018

Surgical risk and benefits of laparoscopic surgery for elderly patients with gastric cancer: a multicenter prospective cohort study.

Gastric Cancer 2018 Dec 11. Epub 2018 Dec 11.

Department of Gastroenterological Surgery, Gastroenterological Center, Cancer Institute Ariake Hospital of Japanese Foundation for Cancer Research, 3-10-6 Ariake, Koto-ku, Tokyo, Japan.

Background: Laparoscopic gastrectomy (LG) might have greater clinical benefits for elderly patients as less invasive surgery; however, there is still little evidence to support its benefit. We evaluated the surgical outcomes of elderly patients in a nationwide prospective cohort study.

Methods: One hundred and sixty-nine participating institutions were identified by stratified random sampling, and were adjusted for hospital volume, type and location. Read More

View Article
December 2018
1 Read

Donor-derived hepatocytes in human hematopoietic cell transplant recipients: evidence of fusion.

Virchows Arch 2018 Dec 12. Epub 2018 Dec 12.

Clinical Research Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N, Seattle, WA, 98109, USA.

Reconstitution of hepatocytes by hematopoietic stem cells-a phenomenon which occurs in rodents under highly selective conditions-results from infrequent fusion between incoming myelomonocytes and host hepatocytes, with subsequent proliferation. Human hematopoietic stem cell transplant recipients have been little studied, with some support for transdifferentiation (direct differentiation). We studied routinely obtained autopsy liver tissue of four female hematopoietic cell transplant recipients with male donors, using a highly specific conjoint immunohistochemistry in situ hybridization light microscopic technique. Read More

View Article
December 2018

Gynecologic radiation oncology patients report unmet needs regarding sexual health communication with providers.

J Cancer Res Clin Oncol 2018 Dec 11. Epub 2018 Dec 11.

Department of Radiation Oncology, University of Michigan, 1500 E Medical Center Drive, Ann Arbor, MI, 48109, USA.

Purpose: Following radiation therapy (RT), women with gynecologic malignancies report high rates of sexual dysfunction, but little is known regarding sexual health communication between these patients and health-care providers. This study assessed these patients' beliefs/attitudes toward providers' sexual history taking.

Methods: Surveys were administered to women who presented for follow-up care for gynecologic cancers in an academic radiation oncology department. Read More

View Article
December 2018

Randomized, double-blind, placebo-controlled, crossover study of the effects of repeated-dose caffeine on neurobehavioral performance during 48 h of total sleep deprivation.

Psychopharmacology (Berl) 2018 Dec 11. Epub 2018 Dec 11.

Sleep and Performance Research Center and Elson S. Floyd College of Medicine, Washington State University, Spokane, WA, USA.

Rationale: Caffeine is widely used as a countermeasure against neurobehavioral impairment during sleep deprivation. However, little is known about the pharmacodynamic profile of caffeine administered repeatedly during total sleep deprivation.

Objectives: To investigate the effects of repeated caffeine dosing on neurobehavioral performance during sleep deprivation, we conducted a laboratory-based, randomized, double-blind, placebo-controlled, crossover, multi-dose study of repeated caffeine administration during 48 h of sleep deprivation. Read More

View Article
December 2018

Reduced activity and connectivity of left amygdala in patients with schizophrenia treated with clozapine or olanzapine.

Eur Arch Psychiatry Clin Neurosci 2018 Dec 11. Epub 2018 Dec 11.

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim/University of Heidelberg, Mannheim, Germany.

Obsessive-compulsive symptoms (OCS) in patients with schizophrenia are a common co-occurring condition, often associated with additional impairments. A subgroup of these patients develops OCS during treatment with second-generation antipsychotics (SGAs), most importantly clozapine and olanzapine. So far, little is known about possible neural mechanism of these SGAs, which seem to aggravate or induce OCS. Read More

View Article
December 2018

Objective image analysis of non-magnifying image-enhanced endoscopy for diagnosis of small depressed early gastric cancers.

Endosc Int Open 2018 Dec 10;6(12):E1445-E1453. Epub 2018 Dec 10.

Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan.

 Gastric cancers (GC) after eradication are difficult to diagnose even by magnifying narrow-band imaging (NBI) or blue laser imaging (BLI) endoscopy. Little is known with regard to non-magnifying (NM)-NBI/BLI for early GC so we examined the efficacy of NM-NBI/BLI for early GC diagnosis.  We retrospectively analyzed the images of 29 small (≤ 1 cm) intramucosal GC that had been treated with endoscopic submucosal dissection and 137 benign depressed lesions (BDLs). Read More

View Article
December 2018

Relationship of Red Blood Cell Distribution Width with Cancer Mortality in Hospital.

Biomed Res Int 2018 14;2018:8914617. Epub 2018 Nov 14.

College of Life and Environmental Science, Wenzhou University, Wenzhou 325000, China.

Background: Red blood cell distribution width (RDW) is a clinical index used to make early diagnosis and to monitor treatment effects in iron deficiency anemia. Recently, several studies have suggested that RDW was associated with mortality from various cancers; however, there has been little evidence regarding RDW and cancer as a whole. Therefore, the purpose of our study was to investigate the relationship of RDW and overall cancer mortality in hospital. Read More

View Article
November 2018

Homozygosity for the SCN10A Polymorphism rs6795970 Is Associated With Hypoalgesic Inflammatory Bowel Disease Phenotype.

Front Med (Lausanne) 2018 27;5:324. Epub 2018 Nov 27.

Division of Gastroenterology & Hepatology, Department of Medicine, Penn State College of Medicine, Hershey, PA, United States.

Hypoalgesic inflammatory bowel disease (IBD), a condition in which patients with active disease do not perceive and/or report abdominal pain, is associated with serious complications and there is a lack of cost-effective, reliable diagnostic methods to identify "at-risk" patients. The voltage-gated sodium channels (VGSC's), Na1.7, Na1. Read More

View Article
November 2018

Interactions Between Immunotoxins and the Plasma Membrane: Implications for CAT-8015 Immunotoxin Therapy.

Front Oncol 2018 27;8:553. Epub 2018 Nov 27.

College of Engineering, Mathematics and Physical Sciences, Department of Physics and Astronomy, University of Exeter, Exeter, United Kingdom.

Acute Lymphoblastic Leukemia (ALL) remains the most frequent cause of cancer-related mortality in children and novel therapies are needed for the treatment of relapsed/refractory childhood ALL. One approach is the targeting of ALL blasts with the immunotoxin CAT-8015. Although CAT-8015 has potent anti-leukemia activity, with a 32% objective response rate in a phase 1 study of childhood ALL, haemolytic-uremic syndrome (HUS) and vascular leak syndrome (VLS), major dose-limiting toxicities, have limited the use of this therapeutic approach in children. Read More

View Article
November 2018

A Call for Discussion About Scope of Competence in Behavior Analysis.

Behav Anal Pract 2018 Dec 24;11(4):424-435. Epub 2018 Oct 24.

3Department of Special Education, Ball State University, Muncie, IN USA.

The field of behavior analysis has defined its scope of practice through credentialing and licensure efforts. However, scope of competence in behavior analysis has received little discussion. Scope of competence refers to activities that the individual practitioner can perform at a certain criterion level (e. Read More

View Article
December 2018

Rapid Assessment of Attention Types for the Treatment of Attention-Maintained Problem Behavior.

Behav Anal Pract 2018 Dec 28;11(4):417-423. Epub 2018 Sep 28.

1Department of Behavioral Psychology, Neurobehavioral Unit Outpatient Clinic, Kennedy Krieger Institute, 9810 Patuxent Woods Drive, Columbia, MD 21046 USA.

In the current study, we expanded previously described attention assessment procedures (e.g., Piazza et al. Read More

View Article
December 2018

Board Certified Behavior Analysts and Psychotropic Medications: Slipshod Training, Inconsistent Involvement, and Reason for Hope.

Behav Anal Pract 2018 Dec 23;11(4):350-357. Epub 2018 Feb 23.

1Western Michigan University, Kalamazoo, MI USA.

People with autism spectrum disorder often receive psychotropic medications and two drugs, risperidone and aripiprazole, are approved for treating "irritability" in this population. A number of authors have suggested that behavior analysts can contribute to the prudent use of such drugs, but little is known regarding Board Certified Behavior Analysts' involvement in practices relevant to the use of psychotropic drugs. We e-mailed Board Certified Behavior Analysts an anonymous web-based survey regarding such practices. Read More

View Article
December 2018
  • Page 1 of 11435