929,534 results match your criteria Literature and medicine[Journal]


Validation of a Rapid Microwave-Assisted Extraction Method and GC-FID Quantification of Total Branched Chain Fatty Acids in Lamb Subcutaneous Adipose Tissue.

J Food Sci 2018 Dec 17. Epub 2018 Dec 17.

School of Agriculture and Food Science, Univ. College Dublin, Belfield, Dublin, 4, Ireland.

A rapid microwave-assisted extraction and derivatization of three branched chain fatty acids (BCFA): 4-methyloctanoic acid (MOA), 4-ethyloctanoic acid (EOA) and 4-methylnonanoic acid (MNA) from subcutaneous adipose tissue (SAT) of lamb was developed and validated. Linearity was excellent (R > 0.99), and the limits of detection and quantification (μg/mL) were between 0. Read More

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December 2018

Adherence to Therapeutic Footwear in Type 2 Diabetes in Malta.

Exp Clin Endocrinol Diabetes 2018 Dec 17. Epub 2018 Dec 17.

Faculty of Health Sciences, University of Malta.

Background: The literature reports that people living with diabetes do not adhere to their prescribed therapeutic footwear as instructed. The reason for this is still uncertian although certain footwear characteristics seem to reasons reported leading to reduced level of adherence.

Objectives: To explore the reasons for current adherence or otherwise to prescribed stock footwear amongst patients living with type-2 diabetes. Read More

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December 2018

Prevalence of asthma in multiple sclerosis: A United States population-based study.

Mult Scler Relat Disord 2018 Dec 12;28:69-74. Epub 2018 Dec 12.

Neuroimmunological Disorders Gene-Environment Epidemiology Laboratory, Department of Population and Quantitative Health Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, USA. Electronic address:

Background: Multiple sclerosis (MS) and asthma are complex multifactorial diseases which adversely impact daily functioning. However, the prevalence of asthma in those with MS is not clear. The objective of this study is to characterize the prevalence of asthma in those with MS, with considerations for age, gender, and race. Read More

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December 2018

Self-compassion and depression, anxiety, and resilience in adults with epilepsy.

Epilepsy Behav 2018 Dec 14;90:154-161. Epub 2018 Dec 14.

Division of Health Research, Faculty of Health and Medicine, Furness College, Lancaster University, Lancaster LA1 4YG, UK. Electronic address:

Background: Research suggests that people with epilepsy (PWE) are more likely to experience depression and anxiety than the general population. Given the adversity associated with the condition, resilience may also be important. However, to date, resilience has been largely overlooked in the epilepsy literature. Read More

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December 2018

The role of neighborhoods in household food insufficiency: Considering interactions between physical disorder, low social capital, violence, and perceptions of danger.

Soc Sci Med 2018 Dec 10;221:58-67. Epub 2018 Dec 10.

The University of Texas at San Antonio, United States.

Rationale: Food insecurity is a significant public health concern, with implications for community and individual health and well-being. Although a growing body of literature points to the role of neighborhoods in household food insecurity, studies using nationally representative samples to explore interactions between neighborhood risks - including violence and danger - are lacking.

Objective: The present study examines whether interactions between physical disorder, low social capital, and violence/danger in the neighborhood have significant implications for the risk of household food insufficiency using a large, nationally representative sample of U. Read More

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December 2018

Systematic review and meta-analysis of basal cortisol levels in Borderline Personality Disorder compared to non-psychiatric controls.

Psychoneuroendocrinology 2018 Dec 10;102:149-157. Epub 2018 Dec 10.

Monash Alfred Psychiatry Research Centre, Central Clinical School, Monash University and The Alfred Hospital, Melbourne, Australia.

Objective: Borderline personality disorder (BPD) is a prevalent, complex, and serious mental disorder involving multiple symptoms and maladaptive behaviour. The underlying psychobiological mechanisms involved are not yet fully understood, but increasing evidence indicates that changes in hypothalamic-pituitary-adrenal stress axis (HPA) activity may contribute to BPD. Whilst various studies have demonstrated elevated levels of cortisol (the end-product of the HPA axis) in BPD sufferers, others have presented opposite findings. Read More

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December 2018

QSAR for baseline toxicity and classification of specific modes of action of ionizable organic chemicals in the zebrafish embryo toxicity test.

Aquat Toxicol 2018 Dec 5;207:110-119. Epub 2018 Dec 5.

UFZ - Helmholtz Centre for Environmental Research, Permoserstr. 15, 04318 Leipzig, Germany; Eberhard Karls University Tübingen, Center for Applied Geoscience, Environmental Toxicology Hölderlinstr. 12, 72074, Tübingen, Germany.

The fish embryo toxicity (FET) test with the zebrafish Danio rerio is widely used to assess the acute toxicity of chemicals thereby serving as animal alternative to the acute fish toxicity test. The minimal toxicity of neutral chemicals in the FET can be predicted with a previously published Quantitative Structure-Activity Relationship (QSAR) based on the liposome-water partition coefficient K. Such a QSAR may serve to plan toxicity testing and to evaluate whether an observed effect is caused by a specific mode of action (MoA). Read More

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December 2018

A systematic literature review and critical appraisal of epidemiological studies on outdoor air pollution and tuberculosis outcomes.

Environ Res 2018 Dec 7;170:33-45. Epub 2018 Dec 7.

School of Public Health, Faculty of Medicine, University of Queensland, Herston, Australia; Centre for Air Pollution, Energy and Health Research, Glebe, NSW, Australia.

Ambient air pollution is the leading environmental risk factor for disease globally. Air pollutants can increase the risk of some respiratory infections, but their effects on tuberculosis (TB) are unclear. In this systematic literature review, we aimed to assess epidemiological studies on the association between outdoor air pollutants and TB incidence, hospital admissions and death (collectively referred to here as 'TB outcomes'). Read More

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December 2018

Justification and reporting of subgroup analyses were lacking or inadequate in randomised controlled trials.

J Clin Epidemiol 2018 Dec 14. Epub 2018 Dec 14.

Norwich Medical School, University of East Anglia, Norwich, Norfolk, U.K.

Objectives: To assess the appropriateness and rationales of subgroup analyses planned in protocols of randomised controlled trials and reported in subsequent corresponding trial publications.

Study Design And Setting: We searched PubMed to identify trial protocols published in journals during 2006-2017. From a total of 3774 initially identified records, we included a random sample of 479 protocols, and identified 280 trial publications corresponding to the included protocols. Read More

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December 2018

Assessing the in vivo data on low/no-calorie sweeteners and the gut microbiota.

Food Chem Toxicol 2018 Dec 14. Epub 2018 Dec 14.

University of Reading, Department of Food and Nutritional Sciences, PO Box 226, Whiteknights, Reading, RG6 6AP, UK.

Low/no-calorie sweeteners (LNCS) are continually under the spotlight in terms of their safety and benefits; in 2014 a study was published linking LNCS to an enhanced risk of glucose intolerance through modulation of the gut microbiota. In response, an in-depth review of the literature was undertaken to evaluate the major contributors to potential changes in the gut microbiota and their corresponding sequelae, and to determine if consuming LNCS (e.g. Read More

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December 2018

MALDI-TOF MS for rapid diagnosis of Anaerobiospirillum succiniciproducens, an unusual causative agent of bacteraemia in humans. Two case reports and literature review.

Anaerobe 2018 Dec 14. Epub 2018 Dec 14.

Clinical Microbiology Department, Hospital Universitario La Paz, Madrid, Spain.

Anaerobiospirillum succiniciproducens is a gram-negative anaerobic spiral rod which is part of the normal flora of dogs and cats and can produce bacteraemia and diarrhoea in humans. In this report we describe two cases of bacteraemia caused by A. succiniciproducens which was successfully identified by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS). Read More

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December 2018

Stress hormones and eating disorders.

Mol Cell Endocrinol 2018 Dec 14. Epub 2018 Dec 14.

Aims: The aim of this paper is to emphasize the role of stress processes in the aetiology of eating disorders.

Methods: We have examined the literature for evidence that people with eating disorders might exhibit markers of stress and show signs of the "maltreated ecophenotype".

Results: Early adversity is more common among people with binge eating behaviours. Read More

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December 2018

Considering the relationship between domestic violence and pet abuse and its significance in the veterinary clinical and educational contexts.

N Z Vet J 2018 Dec 17:1-27. Epub 2018 Dec 17.

a Department of Veterinary Clinical Sciences , University of Melbourne School , Werribee , Victoria , Australia 3030.

This thematic review examines the literature regarding the relationship between domestic violence (DV) and pet abuse (PA) particularly in the veterinary clinical and educational contexts. It examines the significance of this relationship for the veterinary profession including the veterinarian's role and associated legal and ethical obligations, and relevant current veterinary education standards, to identify future clinical and educational directions. Articles were sourced from online databases by searching the keywords without date restrictions. Read More

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December 2018

A pedicled split extended vertical deep inferior epigastric (s-vDIEP) flap and an adipo-dermal thigh local flap for the reconstruction of the medial thigh compartment after sarcoma resection: A case report.

Microsurgery 2018 Dec 17. Epub 2018 Dec 17.

Department of Plastic and Hand Surgery, University Hospital Zurich, Zurich, Switzerland.

Large upper medial thigh defects in prior irradiated tissue require challenging reconstructions. Several techniques have been reported to reconstruct this region and according to the literature, pedicled perforator flaps are the first reconstructive option. The anterolateral thigh flap is considered the gold standard, while surprisingly the pedicle deep inferior epigastric (DIEP) flap in vertical fashion has not been frequently employed, if compared with its muscular counterpart, the pedicle vertical rectus abdomins flap (vRAM). Read More

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December 2018
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The biomarker potential of cell-free microRNA from cerebrospinal fluid in Parkinsonian Syndromes.

Mov Disord 2018 Dec 17. Epub 2018 Dec 17.

Department of Neurology, Bispebjerg University Hospital, Copenhagen, Denmark.

Background: MicroRNAs are small noncoding RNAs involved in the post-transcriptional regulation of protein synthesis. Extracellular microRNAs are accessible in a stable form in biofluids.

Objectives: The aim was to identify individual microRNAs and/or subsets of microRNAs in CSF with biomarker potential and thus identify specific putative pathophysiological pathways. Read More

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December 2018

Benefit-cost analysis of the policy of mandatory annual rabies vaccination of domestic dogs in rabies-free Japan.

PLoS One 2018 17;13(12):e0206717. Epub 2018 Dec 17.

Department of Global Agricultural Sciences, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.

Japan is one of the few rabies-free countries/territories which implement the policy of mandatory vaccination of domestic dogs. In order to assess the economic efficiency of such policy in reducing the economic burden of a future canine rabies outbreak in Japan, a benefit-cost analysis (BCA) was performed using probabilistic decision tree modelling. Input data derived from simulation results of published mathematical model, field investigation conducted by the authors at prefectural governments, literature review, international or Japanese database and empirical data of rabies outbreaks in other countries/territories. Read More

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December 2018

Use of C-reactive protein for the early prediction of anastomotic leak after esophagectomy: Systematic review and Bayesian meta-analysis.

PLoS One 2018 17;13(12):e0209272. Epub 2018 Dec 17.

Department of Biomedical Sciences for Health, Division of General Surgery, University of Milan, IRCCS Policlinico San Donato, Milan, Italy.

Background: Early suspicion, diagnosis, and timely treatment of anastomotic leak after esophagectomy is essential. Retrospective studies have investigated the role of C-reactive protein (CRP) as early marker of anastomotic leakage. The aim of this systematic review and meta-analysis was to evaluate the predictive value of CRP after esophageal resection. Read More

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December 2018

Early-life environmental exposures and childhood growth: A comparison of statistical methods.

PLoS One 2018 17;13(12):e0209321. Epub 2018 Dec 17.

Department of Mathematics and Statistics, Williams College, Williamstown, MA, United States of America.

There is a growing literature that suggests environmental exposure during key developmental periods could have harmful impacts on growth and development of humans. Understanding and estimating the relationship between early-life exposure and human growth is vital to studying the adverse health impacts of environmental exposure. We compare two statistical tools, mixed-effects models with interaction terms and growth mixture models, used to measure the association between exposure and change over time within the context of non-linear growth and non-monotonic relationships between exposure and growth. Read More

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December 2018

Power and sample size calculations for comparison of two regression lines with heterogeneous variances.

Authors:
Gwowen Shieh

PLoS One 2018 17;13(12):e0207745. Epub 2018 Dec 17.

Department of Management Science, National Chiao Tung University, Hsinchu, Taiwan.

The existence of interactive effects of a dichotomous treatment variable on the relationship between the continuous predictor and response variables is an essential issue in biological and medical sciences. Also, considerable attention has been devoted to raising awareness of the often-untenable assumption of homogeneous error variance among treatment groups. Although the procedures for detecting interactions between treatment and predictor variables are well documented in the literature, the corresponding problem of power and sample size calculations has received relatively little attention. Read More

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December 2018

The effectiveness of art therapy for anxiety in adults: A systematic review of randomised and non-randomised controlled trials.

PLoS One 2018 17;13(12):e0208716. Epub 2018 Dec 17.

Faculty of Health, University of Applied Sciences Leiden, Leiden, The Netherlands.

Background: Anxiety disorders are one of the most diagnosed mental health disorders. Common treatment consists of cognitive behavioral therapy and pharmacotherapy. In clinical practice, also art therapy is additionally provided to patients with anxiety (disorders), among others because treatment as usual is not sufficiently effective for a large group of patients. Read More

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December 2018

Who self-medicates? Results from structural equation modeling in the Greater Paris area, France.

PLoS One 2018 17;13(12):e0208632. Epub 2018 Dec 17.

Department of Social Epidemiology, Institut Pierre Louis d'Epidémiologie et de Santé Publique (UMRS 1136), INSERM, Sorbonne Université, Paris, France.

Objectives: Our study aimed to describe the prevalence of self-medication among the Paris adult population and to identify the factors associated with self-medication.

Materials And Methods: This cross-sectional study was based on data collected from the SIRS cohort (a French acronym for "Health, inequalities and social ruptures") in 2005 in the Paris metropolitan area using a face-to-face administration questionnaire among a representative sample of 3,023 French-speaking adults. Structural equation models were used to investigate the factors associated with self-medication in the overall population and according to income. Read More

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December 2018

Quality circles for quality improvement in primary health care: Their origins, spread, effectiveness and lacunae- A scoping review.

PLoS One 2018 17;13(12):e0202616. Epub 2018 Dec 17.

Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.

Quality circles or peer review groups, and similar structured small groups of 6-12 health care professionals meet regularly across Europe to reflect on and improve their standard practice. There is debate over their effectiveness in primary health care, especially over their potential to change practitioners' behaviour. Despite their popularity, we could not identify broad surveys of the literature on quality circles in a primary care context. Read More

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December 2018

Assessment of the ergonomic risk from saddle and conventional seats in dentistry: A systematic review and meta-analysis.

PLoS One 2018 17;13(12):e0208900. Epub 2018 Dec 17.

Department of Community Dentistry, School of Dentistry of Piracicaba, University of Campinas, Piracicaba, SP, Brazil.

Objective: This study aimed to verify whether the saddle seat provides lower ergonomic risk than conventional seats in dentistry.

Methods: This review followed the PRISMA statement and a protocol was created and registered in PROSPERO (CRD42017074918). Six electronic databases were searched as primary study sources. Read More

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December 2018

Association and biomarker potential of elevated serum adiponectin with nephropathy among type 1 and type 2 diabetics: A meta-analysis.

PLoS One 2018 17;13(12):e0208905. Epub 2018 Dec 17.

Graduate School, University of Santo Tomas, Manila City, Philippines.

Background: Managing nephropathy associated with diabetes mellitus warrant investigation of relevant biomarkers in predicting this condition. Adiponectin (ADP) may hold promise as a biomarker for diabetic nephropathy (DN). In this study, we examine associations of ADP with DN by meta-analyzing relevant literature. Read More

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December 2018

Behavior and sleep disturbance in Smith-Magenis syndrome.

Curr Opin Psychiatry 2018 Dec 14. Epub 2018 Dec 14.

Department of Molecular and Human Genetics, Baylor College of Medicine.

Purpose Of Review: To provide an update of the most recent studies on Smith-Magenis syndrome (SMS) with a focus on the unique pattern of behavioral and sleep disturbances associated with the condition.

Recent Findings: The recent literature on SMS has focused on the characteristic severe behavioral and sleep disturbances. A better understanding of the underlying pathophysiological mechanisms and common clinical course has helped further characterize SMS, while much is left to be discovered in regard to effective treatment/management. Read More

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December 2018

Understanding and predicting the longitudinal course of dementia.

Curr Opin Psychiatry 2018 Dec 14. Epub 2018 Dec 14.

Centre for Dementia Prevention, University of Edinburgh, Edinburgh, UK.

Purpose Of Review: To date, most research in dementia has focused either on the identification of dementia risk prediction or on understanding changes and predictors experienced by individuals before diagnosis. Despite little is known about how individuals change after dementia diagnosis, there is agreement that changes occur over different time scales and are multidomain. In this study, we present an overview of the literature regarding the longitudinal course of dementia. Read More

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December 2018
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Retracted publications in emergency medicine.

Eur J Emerg Med 2019 Feb;26(1):71

Department of Tropical Medicine, Hainan Medical University, Haikou, China.

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February 2019

Opioid and Cannabis Co-Use among Adults with Chronic Pain: Relations to Substance Misuse, Mental Health, and Pain Experience.

J Addict Med 2018 Dec 13. Epub 2018 Dec 13.

Department of Psychology, University of Houston, Houston, TX (AHR, JB, DJP, MJV); Department of Psychology, Louisiana State University, Baton Rouge, LA (JDB); College of Nursing, Washington State University, Washington, DC (MFO); Department of Psychology, Syracuse University, New York, NY (JWD); Department of Behavioral Science, The University of Texas MD Anderson Cancer Center (MJZ); and HEALTH Institute, University of Houston, Houston, TX (MJZ).

Objectives: Opioid misuse constitutes a significant public health problem and is associated with a host of negative outcomes. Despite efforts to curb this increasing epidemic, opioids remain the most widely prescribed class of medications. Prescription opioids are often used to treat chronic pain despite the risks associated with use, and chronic pain remains an important factor in understanding this epidemic. Read More

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December 2018

Major Adverse Cardiac Events and Mortality Associated with Electroconvulsive Therapy: A Systematic Review and Meta-analysis.

Anesthesiology 2019 Jan;130(1):83-91

From the Departments of Anesthesiology and Intensive Care (A.D., M.M., B.P.) Emergency Medicine (H.H.), Medical University of Vienna, Vienna, Austria the Department of Anesthesiology, Washington University, St. Louis, Missouri (P.N.) Department of Public Health Sciences, University of Chicago, University of Chicago, Illinois (T.K.).

What We Already Know About This Topic: WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Cardiac events after electroconvulsive therapy have been reported sporadically, but a systematic assessment of the risk is missing. The goal of this study was to obtain a robust estimate of the incidence of major adverse cardiac events in adult patients undergoing electroconvulsive therapy.

Methods: Systematic review and meta-analysis of studies that investigated electroconvulsive therapy and reported major adverse cardiac events and/or mortality. Read More

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January 2019

Female Sexual Function and Sexual Well-being Before and After Breast Reduction: A Pilot Cross-sectional Study and Review of Literature.

Ann Plast Surg 2018 Dec 13. Epub 2018 Dec 13.

Dr Szczyt's Plastic Surgery Clinic, Warsaw, Poland.

Background: Breast reduction is one of the most frequently performed procedures in plastic surgery practice. Patients often undergo this procedure for not only aesthetic but also functional reasons because breast hypertrophy may hinder daily activities because of chronic spinal pain. Breast reduction has a documented impact on quality of life. Read More

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December 2018

Integrative Medicine in Plastic Surgery: A Systematic Review of Our Literature.

Ann Plast Surg 2018 Dec 13. Epub 2018 Dec 13.

Division of General Medicine and Primary Care, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.

Background: Surveys have reported that as high as 80% of plastic surgery patients utilize integrative medicine approaches including natural products (NPs) and mind-body practices (MBPs). Little is known regarding the evidence of benefit of these integrative therapies specifically in a plastic surgery patient population.

Methods: We conducted a systematic review of studies in MEDLINE, PubMed, and EMBASE (inception through December 2016) evaluating integrative medicine among plastic surgery patients. Read More

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December 2018

Abnormal Presentation of Aggressive Fibromatosis After Radiotherapy for Keloids: Case Report and Brief Literature Review.

Ann Plast Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Burn and Plastic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Rationale: Keloids, dermal fibroproliferative lesions, often occur secondary to skin injury and extend beyond the margins of the original lesion. Aggressive fibromatosis (AF) is a rare condition arising from fibroblasts and is characterized clinically as a nonmetastasizing but locally invasive tumor. In this work, we present the case of a patient who developed AF in the chest 3 years after surgery and postoperative radiotherapy for keloids. Read More

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December 2018
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Modified V-Y Fasciocutaneous Flap Reconstruction After Abdominoperineal Resection in Irradiated Patients Prevents Wound Dehiscence and Associated Complications: A Retrospective Analysis and Benchtop Confirmation.

Ann Plast Surg 2018 Dec 13. Epub 2018 Dec 13.

Division of Plastic and Reconstructive Surgery, Duke University Medical Center, Durham NC.

Background: Primary perineal closure following abdominal perineal resection (APR) is reported to have a wound complication rate as high as 66%, whereas flap reconstruction reduces wound complications to 15% to 35%. A modified de-epithelialized V-Y fasciocutaneous flap aims to further improve results in this patient population.

Methods: To study the breaking force of a simple interrupted suture in either skin or subcutaneous fat, various quantitative assessments were performed in a porcine flap model using uniaxial static tensile testing with an Instron tensiometer, with a single or triple row of 3 Vicryl sutures in both skin and fat. Read More

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December 2018
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Towards UNAIDS Fast-Track goals: Targeting priority geographic areas for HIV prevention and care in Zimbabwe.

AIDS 2018 Dec 13. Epub 2018 Dec 13.

Ministry of Health and Child Care, Harare, Zimbabwe.

Introduction: Zimbabwe has made substantial progress toward the Joint United Nations Programme on HIV/AIDS (UNAIDS) targets of 90-90-90 by 2020, with 73% of people living with HIV diagnosed, 87% of those diagnosed on antiretroviral therapy (ART), and 86% of those on ART virally suppressed. Despite this exceptional response, more effort is needed to completely achieve the UNAIDS targets. Here, we conducted a detailed spatial analysis of the geographical structure of the HIV epidemic in Zimbabwe to include geographical prioritization as a key component of their overall HIV intervention strategy. Read More

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December 2018

From A to D: A Unique Case Report of Recovery after Longitudinal Myelitis Related to Lupus.

Am J Phys Med Rehabil 2018 Dec 14. Epub 2018 Dec 14.

HealthPartners Neuroscience Center, St. Paul, MN, USA.

Longitudinal myelitis secondary to an acute flare of systemic lupus erythematosus (SLE) has been reported in the literature. There have been few published cases of complete functional recovery in patients with systemic lupus erythematosus related longitudinal myelitis (SLE-LM). Of those cases, none have described in detail the rehabilitation course of treatment. Read More

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December 2018
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NIAAA's College Alcohol Intervention Matrix.

Alcohol Res 2018 ;39(1):43-47

Jessica M. Cronce, Ph.D., is an assistant professor in the Department of Counseling Psychology and Human Services, College of Education, University of Oregon, Eugene, Oregon. Traci L. Toomey, Ph.D., is a professor in the Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota. Kathleen Lenk, M.P.H., is a senior research fellow in the Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota. Toben F. Nelson, Sc.D., is an associate professor in the Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota. Jason R. Kilmer, Ph.D., is an assistant director of Health and Wellness for Alcohol and Other Drug Education and an associate professor in the Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle, Washington. Mary E. Larimer, Ph.D., is a professor in the Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle, Washington.

The College Alcohol Intervention Matrix (CollegeAIM) is a user-friendly, interactive decision tool based on a synthesis of the substantial and growing literature on campus alcohol use prevention. It includes strategies targeted at both the individual and environmental levels. Commissioned by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), CollegeAIM reflects the collective knowledge of 16 separate experts in the field, which makes it unique relative to other summaries of the science. Read More

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January 2018

"Maturing Out" of Binge and Problem Drinking.

Alcohol Res 2018 ;39(1):31-42

Matthew R. Lee, Ph.D., is research assistant professor, Department of Psychological Sciences, University of Missouri, Columbia, Missouri. Kenneth J. Sher, Ph.D., is curators' distinguished professor, Department of Psychological Sciences, University of Missouri, Columbia, Missouri.

This article reviews literature aiming to explain the widespread reductions in binge and problem drinking that begin around the transition to young adulthood (i.e., "maturing out"). Read More

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January 2018

Nonlinear Indices with Applications to Schizophrenia and Bipolar Disorder.

Nonlinear Dynamics Psychol Life Sci 2019 Jan;23(1):17-56

Western University, London, ON, Canada.

In this article we study the application of nonlinear indices (sometimes called complexity indices) to univariate time series data arising from studies of schizophrenia and bipolar disorder. Specifically, we consider time series arising from EEG studies, ECG studies, and self-report mood data. As part of our analysis, we empirically examine the claim in the literature that complexity tends to be higher in the EEG of schizophrenia patients than controls and that this tendency is dampened or even inverted by medication, increasing age, and reduced symptomatology. Read More

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January 2019

Radiologist-rheumatologist multidisciplinary approach in the management of axial spondyloarthritis: a Delphi consensus statement.

Clin Exp Rheumatol 2018 Nov 16. Epub 2018 Nov 16.

Department of Medical, Surgical and Neurosciences, Diagnostic Imaging, University of Siena, Azienda Ospedaliera Universitaria Senese, Siena, Italy.

Objectives: The aim of this study was to develop a Delphi consensus statement between rheumatologists and radiologists for the diagnosis and monitoring of axial spondyloarthritis (axial-SpA).

Methods: Following an extensive literature search to identify unmet needs and potential goals for a multidisciplinary approach, a scientific board comprising 28 Italian hospital-based rheumatologists (n=19) and radiologists (n=9) identified 8 "starting points", resulting in the development of 23 consensus statements covering issues from current practice guidelines to specific MRI protocols for the assessment of axial-SpA. Each participant anonymously expressed a level of agreement for each statement using a 5-point Likert scale (1="strongly disagree"; 5="strongly agree") via an online Delphi method. Read More

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November 2018

The relationship between pressure ulcer risk assessment and preventative interventions: a systematic review.

J Wound Care 2018 Dec;27(12):862-875

Professor of Nursing, School of Nursing, Midwifery and Paramedicine, Faculty of Health Sciences, Australian Catholic University, 1100 Nudgee Road, Banyo, QLD, Australia 4014. Nursing Research and Practice Development Centre, The Prince Charles Hospital, Rode Rd, Chermside, QLD, Australia 4032. Faculty of Health Sciences, University of Witwatersrand, South Africa.

Objective:: Hospital-acquired pressure ulcers (PU) continue to occur despite an ongoing focus on prevention. The aim of this review was to identify and evaluate primary research which links pressure ulcer risk assessment with prescription and implementation of preventative interventions for hospitalised adults.

Method:: A systematic review of the databases EBSCO CINAHL Complete, EBSCO MEDLINE Complete, Scopus and Web of Science was undertaken, using search terms related to pressure ulcers, hospital-acquired, risk, planning, implementation, prevention and outcome. Read More

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December 2018

Peri-Implantitis and Peri-Implant Mucositis Case Definitionsin Dental Research: A Systematic Assessment.

J Oral Implantol 2018 Dec 17. Epub 2018 Dec 17.

1 Tufts University School of Medicine Periodontology Tufts University School of Medicine.

The aim of this review was to determine which are the most common peri-implant mucositis and peri-implantitis case definitions that have been used worldwide in implant dentistry literature. A systematic assessment on peri-implant disease classification was conducted using all publications in MEDLINE, EMBASE, SCOPUS, and Google Scholar between 1994 and November 2017. Screening of eligible studies and data extraction were conducted in duplicate and independently by two reviewers. Read More

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December 2018

Unexpected foreign body in the bladder of a spinal cord injured patient: A case report.

J Spinal Cord Med 2018 Dec 17:1-3. Epub 2018 Dec 17.

a Department of Physical Medicine and Rehabilitation , Gaziosmanpasa Taksim Training and Research Hospital , Istanbul , Turkey.

Context: Bladder dysfunction is common in patients with spinal cord injuries. Clean intermittent catheterization is a preferred method of neurogenic bladder management among spinal cord injured patients. Some complications may occur due to the use of clean intermittent catheterization. Read More

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December 2018

Reversibility of castration resistance status after Radium-223 dichloride treatment: Clinical evidence and Review of the literature.

Int J Radiat Biol 2018 Dec 17:1-29. Epub 2018 Dec 17.

a Department of Radiological Sciences, Oncology and Anatomical Pathology , Sapienza University of Rome , Viale Regina Elena 324 , 00161 , Rome , Italy.

Purpose: In the history of prostate cancer, some of patients progresses to castration resistant prostate cancer (CRPC) stage and, although new drugs and treatment protocols have been introduced, CRPC presents poor prognosis. This review focused on biological mechanisms, underlying CRPC described in scientific literature in order to explain the reversion of resistance to castration. We present the case of a 73 years-old man, affected by bone metastatic CRPC, early treated with Radium-223 with a complete response. Read More

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December 2018

Disruptions in the Amount and Timing of Sleep and Repetitive Negative Thinking in Adolescents.

Behav Sleep Med 2018 Dec 17:1-9. Epub 2018 Dec 17.

a Department of Psychology , State University of New York Binghamton , Binghamton , NY.

Objective/background: Numerous psychiatric conditions characterized by repetitive negative thinking (RNT) are also frequently associated with disruptions in the duration and timing of sleep. The emerging literature supports that these types of sleep disruptions may be associated with negative psychological consequences such as depressed mood, anxiety, and poor emotion regulation, all of which have features of RNT. There is a paucity of research on the association between RNT and disruptions in sleep duration and timing in adolescents. Read More

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December 2018

Overcoming the emerging drug resistance of smoothened: an overview of small-molecule SMO antagonists with antiresistance activity.

Future Med Chem 2018 Dec 17. Epub 2018 Dec 17.

Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44, West Culture Road, Ji'nan 250012, PR China.

Hedgehog (HH) signaling pathway plays vital roles in controlling embryonic cell fate and homeostatic, and becomes dormant in mature individuals, aberrant activation of HH signaling pathway is involved in a number of human cancers. Smoothened (SMO), a vital transducer of HH signaling pathway, attracts significant attentions in HH signaling pathway-related cancer therapy. The approval of SMO antagonists Vismodegib proves that SMO is a promising therapeutic target, and a number of SMO antagonists are reported since then. Read More

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December 2018

Drilling in the dorid species Vayssierea cf. elegans (Gastropoda: Nudibranchia): Functional and comparative morphological aspects.

J Morphol 2019 Jan;280(1):119-132

Invertebrate Zoology Department, Biological Faculty, M.V. Lomonosov Moscow State University, Moscow, Russia.

The drilling mode of feeding is known from two clades of Gastropoda: Caenogastropoda and Heterobranchia. However, the level of convergence and parallelism or homology among these two lineages is unclear. The morphology of the buccal complex is well studied for drilling caenogastropods, but poorly known for drilling nudibranchs. Read More

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January 2019

An appraisal of the role of specific bacteria in the initial pathogenesis of periodontitis.

J Clin Periodontol 2018 Dec 17. Epub 2018 Dec 17.

Department of Applied Oral Sciences, Center for Periodontology, The Forsyth Institute, Cambridge, Massachusetts, USA.

Background: Historically, inflammatory periodontal diseases (gingivitis and periodontitis) have been recognized as being primarily of bacterial origin. Bacteria are necessary for disease development, but the presence of specific bacteria does not guarantee progression to periodontitis. Periodontitis is a multifactorial disease; specific bacteria are associated with disease, but may not be the target of treatment. Read More

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December 2018

A meta-analysis of the effect of microRNA-34a on the progression and prognosis of gastric cancer.

Authors:
Z Li Z-M Liu B-H Xu

Eur Rev Med Pharmacol Sci 2018 Dec;22(23):8281-8287

Department of Interventional Therapy, Harrison International Peace Hospital, Hengshui, Hebei, China.

Objective: To explore the value of microRNA-34a (miR-34a) as a diagnostic biomarker of gastric cancer development and prognosis.

Materials And Methods: PubMed, Web of Science, Embase, CNKI, Wanfang Database and Gene Expression Omnibus (GEO) were searched according to the key words for the literature about the expression of microRNA-34a in the serum or tissues of gastric cancer patients. The data of gene expression were extracted and the data were analyzed by Stata 14. Read More

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December 2018

Predictive value of 18F-FDG PET/CT on survival in locally advanced rectal cancer after neoadjuvant chemoradiation.

Eur Rev Med Pharmacol Sci 2018 Dec;22(23):8227-8236

Department of Interdisciplinary Medicine, Nuclear Medicine Unit, University of Bari "Aldo Moro", Bari, Italy.

Objective: To evaluate the prognostic value of 18F-FDG PET/CT in terms of survival in patients with locally advanced rectal cancer (LARC) who had undergone surgery preceded by neoadjuvant chemoradiotherapy (nCRT). Moreover, the existence of correlation between Overall Survival (OS) and Disease Free Survival (DFS) with pathological staging ((y)pTNM and TRG) was evaluated.

Patients And Methods: A total of 58 patients with biopsy-proven of LARC were included. Read More

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December 2018

Assessment of Instruments for Measurement of Delirium Severity: A Systematic Review.

JAMA Intern Med 2018 Dec 17. Epub 2018 Dec 17.

Aging Brain Center, Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts.

Importance: Measurement of delirium severity has been recognized as highly important for tracking prognosis, monitoring response to treatment, and estimating burden of care for patients both during and after hospitalization. Rather than simply rating delirium as present or absent, the ability to quantify its severity would enable development and monitoring of more effective treatment approaches for the condition.

Objectives: To present a comprehensive review of delirium severity instruments, conduct a methodologic quality rating of the original validation study of the most commonly used instruments, and select a group of top-rated instruments. Read More

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December 2018
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