Search our Database of Scientific Publications and Authors

I’m looking for a

    6412 results match your criteria Liposarcoma

    1 OF 129

    Liposarcoma of the spermatic cord associated with scrotum lipoma: A case report and review of the literature.
    Urol Case Rep 2018 Mar 2;17:114-116. Epub 2018 Feb 2.
    Osaka Rosai Hospital, Japan.
    Liposarcoma of the spermatic cord is a rare disease and often mistakenly diagnosed as inguinal hernia, hydrocele, and lipoma. We report the case of a 58-year-old man who presented with persistent discomfort and swelling on the left inguinal region. He was diagnosed with left scrotum lipoma when he was 12 years old. Read More

    [Adrenal myelolipoma: about a case].
    Pan Afr Med J 2017 18;28:153. Epub 2017 Oct 18.
    Service d'Endocrinologie Diabétologie Maladies Métaboliques et Nutrition, Laboratoire PCIM, FMPM, Université Cadi Ayyad, CHU Mohamed VI, Marrakech.
    Adrenal myelolipoma is a rare benign non secreting tumor. It is often unexpectedly detected. Pathophysiologically, it is adrenal cortex cell metaplasia into reticuloendothelial cells, resulting from infection, chronic stress or adrenal gland degeneration. Read More

    Dedifferentiated Liposarcoma With Rhabdomyosarcomatous Differentiation Producing HCG: A Case Report of a Diagnostic Pitfall.
    Int J Surg Pathol 2018 Mar 1:1066896918760192. Epub 2018 Mar 1.
    2 University of Miami Miller School of Medicine/Jackson Memorial Hospital, Miami, FL, USA.
    We report a first case of paraneoplastic human chorionic gonadotropin (HCG) production in a dedifferentiated liposarcoma with rhabdosarcomatous differentiation in an 83-year-old man with a retroperitoneal mass, unilateral scrotal enlargement, and a serum HCG level of 843 IU/L. Core biopsy of the retroperitoneal mass revealed rhabdomyosarcoma. Orchiectomy revealed a paratesticular dedifferentiated liposarcoma with rhabdosarcomatous differentiation. Read More

    Pseudo liposarcomatous plasma cells in a patient with liposarcoma and lymphoplasmacytic lymphoma.
    Clin Case Rep 2018 Mar 6;6(3):529-530. Epub 2018 Feb 6.
    Department of Transversal DisciplinesDivision of PathologyCity Hospital TriemliZurichSwitzerland.
    First, patients may always develop a second severe illness, even a second cancer. Second, things are not always as they are expected to be. So, careful diagnosis is mandatory. Read More

    Differentiating and Categorizing of Liposarcoma and Synovial Sarcoma Neoplasms by Fluorescence in Situ Hybridization.
    Iran J Pathol 2017 1;12(3):209-217. Epub 2017 Jul 1.
    Hematology, Oncology and Stem Cell Transplantation Research center, Tehran University of Medical Sciences, Tehran, Iran.
    Background & Objective: Soft tissue sarcomas (STS) constitute an uncommon and heterogeneous group of tumors of mesenchymal origin and various cytogenetic abnormalities ranging from distinct genomic rearrangements, such as chromosomal translocations and amplifications, to more intricate rearrangements involving multiple chromosomes. Fluorescence in situ hybridization (FISH) can be used to identify these chromosomal translocations and amplifications, and sub classify STS precisely. The current study aimed at investigating the usefulness of FISH, as a diagnostic ancillary aid, to detect cytogenetic abnormalities such as(murine double minute 2amplification and(C/EBP homologous protein) rearrangement in liposarcoma, as well as(synaptotagminrearrangement in synovial sarcoma. Read More

    Synovial Sarcoma Is Not Associated With a Higher Risk of Lymph Node Metastasis Compared With Other Soft Tissue Sarcomas.
    Clin Orthop Relat Res 2018 Mar;476(3):589-598
    A. J. Jacobs, Hofstra Northwell School of Medicine, Hempstead, NY, USA; and Department of Family Medicine, Northwell-Southside Hospital, Bay Shore, NY, USA C. D. Morris, A. S. Levin, Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    Background: Reported rates of the incidence of lymph node metastasis in soft tissue sarcoma vary considerably. Many are based on single-institution series and small patient populations. Certain sarcoma subtypes, including synovial sarcoma, have been associated with a higher risk of lymph node involvement. Read More

    Malignant Mesothelioma in Individuals With Nonmesothelial Neoplasms.
    Arch Pathol Lab Med 2018 Mar 12. Epub 2018 Mar 12.
    From the Department of Pathology and Laboratory Medicine, University of Vermont, Burlington (Dr Butnor); and the Department of Pathology, Duke University, Durham, North Carolina (Drs Pavlisko, Sporn, and Roggli).
    Context: - Malignant mesothelioma (MM) is a component of the BAP1 tumor predisposition syndrome. Other than in BAP1 familial studies, nonmesothelial neoplasms in individuals with MM has not been comprehensively assessed.

    Objective: - To assess the spectrum and prevalence of nonmesothelial neoplasms in individuals with MM. Read More

    Extensive renal sinus lipomatosis in xanthogranulomatous pyelonephritis simulating liposarcoma.
    Int Braz J Urol 2018 Mar 9;44. Epub 2018 Mar 9.
    Departamento de Radiologia, Hospital das Clínicas da Universidade de São Paulo HC-FMUSP, São Paulo, Brasil.
    Renal replacement lipomatosis is a condition characterized by varying degrees of renal parenchymal atrophy and perirenal fibrofatty proliferation secondary to chronic inflammation such as xanthogranulomatous pyelonephritis. In severe cases, imaging findings can be misdiagnosed as retroperitoneal liposarcoma. Read More

    Salvage Surgery for Recurrent Retroperitoneal Well-Differentiated Liposarcoma: Early Reoperation may not Provide Benefit.
    Ann Surg Oncol 2018 Mar 8. Epub 2018 Mar 8.
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
    Purpose: Current evidence regarding salvage resection for recurrent retroperitoneal (RP) sarcomas generally lacks detailed histology-specific analyses, but the aggressiveness of these tumors varies widely by histology. We investigated associations between timing and extent of salvage surgery and survival outcomes in patients with recurrent RP well-differentiated liposarcoma (WDLPS).

    Methods: The University of Texas MD Anderson Cancer Center Surgical Oncology sarcoma database was reviewed to identify patients with RP WDLPS who underwent surgical resection for first recurrent disease (salvage surgery) in 1995-2015. Read More

    Fatty Images of the Heart: Spectrum of Normal and Pathological Findings by Computed Tomography and Cardiac Magnetic Resonance Imaging.
    Biomed Res Int 2018 9;2018:5610347. Epub 2018 Jan 9.
    Department of Radiological, Oncological and Anatomo-Pathological Sciences, Policlinico Umberto I, Sapienza University of Rome, Viale Regina Elena 324, 00161 Rome, Italy.
    Ectopic cardiac fatty images are not rarely detected incidentally by computed tomography and cardiac magnetic resonance, or by exams focused on the heart as in general thoracic imaging evaluations. A correct interpretation of these findings is essential in order to recognize their normal or pathological meaning, focusing on the eventually associated clinical implications. The development of techniques such as computed tomography and cardiac magnetic resonance allowed a detailed detection and evaluation of adipose tissue within the heart. Read More

    A Rare Primary Dumbbell Lipoblastoma.
    Asian J Neurosurg 2018 Jan-Mar;13(1):83-85
    Department of Neurosurgery, DMCH, Ludhiana, Punjab, India.
    Lipomas and lipoblastomas are benign tumors of mesenchymal origin in contrast to liposarcoma that is a malignant tumor. Atypical lipomatous lesion arising from embryonal fat cells is termed as lipoblastoma. In the present case report 9-month-old male presented to us with painless, rapidly progressing mass over back, power was normal in all four limbs, fine needle aspiration cytology was suggestive of cellular tissue, magnetic resonance imaging suggestive of well-defined enhancing mass in paravertebral location, extending from D3 to D10 vertebrae with intraspinal extension, communicating through neural foramina at level of D7. Read More

    Extraskeletal Osteosarcoma: MDM2 and H3K27me3 analysis of 19 cases suggest disease heterogeneity.
    Histopathology 2018 Feb 28. Epub 2018 Feb 28.
    Department of Pathology and Clinical Laboratories, National Cancer Center Hospital, Tokyo, Japan.
    Aims: Extraskeletal osteosarcoma (ESOS) is a sarcoma in the non-skeletal tissue that directly produces neoplastic osteoid or bone. Dedifferentiated liposarcoma (DDLPS) and malignant peripheral nerve sheath tumor (MPNST) are the two most common types of sarcoma that can harbor heterologous osteosarcomatous differentiation. We aimed to determine the potential relationship of ESOS to DDLPS and MPNST. Read More

    A Phase II Study of Tumor Ablation in Patients with Metastatic Sarcoma Stable on Chemotherapy.
    Oncologist 2018 Feb 27. Epub 2018 Feb 27.
    School of Medicine, Washington University in St. Louis, St. Louis, Missouri, USA.
    Lessons Learned: Ablation therapy appears to be a reasonably safe and effective approach to obtain a significant treatment-free interval for a subset of patients with limited sites of metastatic disease for which systemic control can be obtained with six cycles of chemotherapy.

    Background: Metastatic sarcoma often becomes resistant to treatment by chemotherapy. There is sometimes prolonged stable disease from active chemotherapy that provides a window of opportunity for an intervention to prolong disease-free survival. Read More

    Gastric liposarcoma in a patient with severe obesity.
    Ann R Coll Surg Engl 2018 Feb 27:e1-e3. Epub 2018 Feb 27.
    Department of Surgery, Riviera-Chablais Hospital , Monthey , Switzerland.
    Liposarcoma is the most common soft tissue sarcoma in adults. Predominant locations are the limbs and retroperitoneum. Intra-abdominal liposarcoma represents only 2% of all cases and visceral location is exceptional. Read More

    Myxoid-round cell liposarcoma: MRI appearance after radiation therapy and relationship to response.
    Radiol Case Rep 2017 Dec 12;12(4):811-814. Epub 2017 Aug 12.
    Department of Radiology, University of Illinois Hospital & Health Sciences System, 1740 West Taylor Street, Suite 2600, Chicago, IL 60612.
    Liposarcomas are classified into 4 different subtypes, with the myxoid-round cell variant demonstrating increased morbidity and metastatic potential dependent on cell composition. Unique to sarcomas, the myxoid-round cell liposarcoma is remarkably sensitive to radiation therapy in the pretreatment setting, owing to the tumor morphology and vascular distribution. Herein we report a case of myxoid-round cell liposarcoma within the deep soft tissues of the thigh of an 81-year-old male with excellent neoadjuvant response to radiation. Read More

    An unusual clinical presentation of myxoid dermatofibrosarcoma protuberans with a prominent vasculature: a potential pitfall in the diagnosis of myxoid soft tissue tumors.
    J Cutan Pathol 2018 Feb 22. Epub 2018 Feb 22.
    University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, USA.
    Dermatofibrosarcoma protuberans (DFSP) is a rare soft tissue tumor that arises primarily on the trunk and extremities but seldom on the scalp. Several variants of DFSP have been described, including myxoid DFSP. Although typical DFSP may have focally myxoid areas, myxoid DFSP, in which most of the stroma is myxoid, is rare and can pose diagnostic challenges. Read More

    Pleomorphic liposarcoma: An analysis of 6 case reports and literature review.
    Medicine (Baltimore) 2018 Feb;97(8):e9986
    Department of General Surgery, Fuling Central Hospital of Chongqing City, Chongqing.
    Rationale: Pleomorphic liposarcoma (PLS), is a rare subtype of liposarcoma, and is considered to be of the highest malignancy grade.

    Patient Concerns: We aimed to analyze the clinical features, diagnosis, treatment, and recurrence of the 6 cases of PLS.

    Diagnoses: Six cases with confirmed pathological PLS presented at out hospital from January 2003 to January 2017. Read More

    Presence of TERT Promoter Mutations is a Secondary Event and Associates with Elongated Telomere Length in Myxoid Liposarcomas.
    Int J Mol Sci 2018 Feb 18;19(2). Epub 2018 Feb 18.
    Department of Hematology, Oncology, Haemostaseology and Stem Cell Transplantation, RWTH Aachen University Medical Faculty, 52074 Aachen, Germany.
    The occurrence ofpromoter mutations has been well described in soft tissue sarcomas (STS). However, the biological role of these mutations as well as their impact on telomere length in STS is still unclear. We analyzed 116 patient samples diagnosed with 22 distinct histological subtypes of bone and STS for the occurrence ofpromoter mutations by Sanger sequencing. Read More

    Use of endoscopic-guided electrocautery ablation for treatment of tracheal liposarcoma in a dog.
    J Am Vet Med Assoc 2018 Mar;252(5):581-585
    CASE DESCRIPTION A 7-year-old 44-kg (97-lb) neutered male Great Pyrenees was referred for evaluation because of episodic dyspnea with cyanosis of 1 to 2 weeks' duration. Three days prior to evaluation, the clinical signs had worsened, including 1 episode of collapse. CLINICAL FINDINGS Thoracic radiography and CT revealed a well-delineated soft tissue mass, located approximately 1. Read More

    Pancreaticoduodenectomy in the surgical management of primary retroperitoneal sarcoma.
    Eur J Surg Oncol 2018 Feb 5. Epub 2018 Feb 5.
    Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
    Background: In retroperitoneal sarcoma (RPS), the optimal extent of resection must balance adequate disease control with potential for morbidity. We sought to study the frequency and outcomes after a Whipple procedure or pancreaticoduodenectomy (PD) in patients undergoing resection for primary RPS.

    Methods: Participating referral centers within the Trans-Atlantic Retroperitoneal Sarcoma Working Group provided retrospective data from January 2007 to December 2016 for patients with primary RPS who underwent PD along with the total number of consecutive resections done during the same time period. Read More

    Malignant fibrous histiocytoma in a patient presenting with urinary system symptoms.
    Rev Assoc Med Bras (1992) 2017 Nov;63(11):950-952
    Canakkale Onsekiz Mart University, Faculty of Medicine, Radiology, Canakkale, Turkey.
    Malignant fibrous histiocytoma is a rare tumor. It is most commonly seen in individuals between the fifth and seventh decades of life, in extremities, and less frequently in the retroperitoneum. Although its etiology is not clearly known, radiotherapy, chemical agents, previous history of surgery, trauma and fracture, and Hodgkin lymphoma have been blamed. Read More

    Pleomorphic liposarcoma of bone: a rare primary malignant bone tumour.
    Clin Sarcoma Res 2018 9;8. Epub 2018 Feb 9.
    1Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Nuffield Orthopaedic Centre, University of Oxford, Oxford, OX3 7HE UK.
    Background: Liposarcoma is an extremely rare primary bone sarcoma.

    Case Presentation: We report a case of primary pleomorphic liposarcoma that arose in an 18 year old male in the metaphysis of the left tibia. Plain radiographs showed a partly sclerotic lesion and MR imaging a heterogeneous tumour predominantly isointense on T1- and high-signal on T2-weighted sequences with focal areas of increased T1 signal that suppressed with fat saturation. Read More

    Dedifferentiated primary mediastinal liposarcoma mimicking a thymic tumor.
    Pathologica 2017 Dec;109(4):401-404
    Paris V University.
    Mediastinal tumors are heterogeneous and the diagnosis depends on their location in the mediastinum. The most frequent tumors are germinal tumor, lymphoma and thymoma. The clinical and radiological aspects are often not sufficient to orient the diagnosis and biopsy is necessary to confirmed it. Read More

    Advances in the treatment of soft tissue sarcoma: focus on eribulin.
    Cancer Manag Res 2018 1;10:207-216. Epub 2018 Feb 1.
    Royal Marsden Hospital, London, UK.
    Eribulin mesylate is a synthetic derivative of halichondrin B isolated from a marine sponge. Its mechanism of action is through microtubule inhibition, which is different from that of taxanes. Eribulin has been approved for the treatment of metastatic breast cancer and more recently for non-operable or metastatic liposarcoma in patients who have received prior anthracycline chemotherapy. Read More

    Acute haemorrhage from a retroperitoneal liposarcoma: a rare presentation.
    BMJ Case Rep 2018 Feb 8;2018. Epub 2018 Feb 8.
    Department of Urology, Princess Alexandra Hospital NHS Trust, Harlow, UK.
    A previously healthy 61-year-old Caucasian woman presented to the emergency department after collapsing at home with associated abdominal pain radiating to her back. An urgent CT angiogram was requested to rule out a ruptured aortic aneurysm. This showed a large 21 cm fat-containing lesion arising from the mid-pole of the left kidney, with an adjacent 4 cm perirenal haematoma. Read More

    A retrospective, single-center cohort study on 65 patients with primary retroperitoneal liposarcoma.
    Oncol Lett 2018 Feb 5;15(2):1799-1810. Epub 2017 Dec 5.
    Department of General Surgery and Center of Minimal Invasive Gastrointestinal Surgery, Southwest Hospital, Third Military Medical University, and Key Laboratory of Tumor Immunopathology of Ministry of Education of China, Chongqing 400038, P.R. China.
    Primary retroperitoneal liposarcoma (PRPLS) is the most common soft tissue malignancy of the retroperitoneum. To determine the pathological features and the curative effects of surgery in patients with PRPLS, and to elucidate key prognostic factors, the present study retrospectively analyzed the clinical cases of 65 patients with PRPLS. Immunohistochemical analysis demonstrated that vimentin and Ki-67 are better indicators for PRPLS immunohistochemical diagnosis compared with S-100 protein. Read More

    Plastic roles of phenylalanine and tyrosine residues of TLS/FUS in complex formation with the G-quadruplexes of telomeric DNA and TERRA.
    Sci Rep 2018 Feb 12;8(1):2864. Epub 2018 Feb 12.
    Institute of Advanced Energy, Kyoto University, Gokasho, Uji, Kyoto, 611-0011, Japan.
    The length of a telomere is regulated via elongation and shortening processes. Telomeric DNA and telomeric repeat-containing RNA (TERRA), which both contain G-rich repeated sequences, form G-quadruplex structures. Previously, translocated in liposarcoma (TLS) protein, also known as fused in sarcoma (FUS) protein, was found to form a ternary complex with the G-quadruplex structures of telomeric DNA and TERRA. Read More

    Expression of MDM2 and p16 in Angiomyolipoma.
    Hum Pathol 2018 Feb 9. Epub 2018 Feb 9.
    Department of Pathology, Hospital for Special Surgery, New York, NY.
    Angiomyolipoma (AML) arises primarily from the kidney, but may grow into the retroperitoneal space mimicking a primary retroperitoneal tumor. Fine needle aspiration (FNA) and core needle biopsy (CNB) of AML, particularly the fat-predominant variant, may be difficult to distinguish from retroperitoneal well-differentiated liposarcoma (WDLS) or lipoma. Commonly used immunomarkers, MDM2 and p16, have proven useful in diagnosing WDLS and dedifferentiated liposarcoma (DDLS), while HMB45 and Melan-A are melanocyte-related markers characteristically expressed in AML. Read More

    [Clinicopathologic features of atypical spindle cell lipomatous tumor].
    Zhonghua Bing Li Xue Za Zhi 2018 Feb;47(2):99-104
    Department of Pathology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, China.
    To investigate the clinicopathologic characteristics, immunophenotype, differential and diagnostic features of atypical spindle cell lipomatous tumor (ASLT).Three cases of ASLT were collected from January 2010 to March 2017 at Zhejiang Provincial People's Hospital. The clinical and imaging features, histomorphology, immunophenotype and prognosis were analyzed. Read More

    [Retroperitoneal dedifferentiated liposarcoma with rhabdomyoblastic differentiation: a clinicopathological analysis].
    Zhonghua Bing Li Xue Za Zhi 2018 Feb;47(2):94-98
    Department of Pathology, Peking University International Hospital, Beijing 102206, China.
    To investigate the clinicopathological features, differential diagnosis, treatment and prognosis of dedifferentiated liposarcoma with rhabdomyoblastic differentiation.Six cases of retroperitoneal dedifferentiated liposarcoma with rhabdomyoblastic features were collected from December 2014 to August 2017 at Peking University International Hospital. The clinical manifestations, histomorphology, immunophenotype, treatment and follow-up data were analyzed, and relevant literature reviewed. Read More

    Neurofibroma involving obturator nerve mimicking an adnexal mass: a rare case report and PRISMA-driven systematic review.
    J Ovarian Res 2018 Feb 9;11(1):14. Epub 2018 Feb 9.
    Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
    Background: Pelvic masses are a common gynecologic problem, and majority of them are diagnosed as ovarian tumors finally. Sometimes, it is hard to distinguish the origin of these pelvic masses. The following case is a solitary neurofibroma arising from the right-side obturator nerve, which was impressed as a right-side ovarian tumor initially. Read More

    Primary Pleomorphic Liposarcoma of Fallopian Tube with Recurrence: A Case Report and Review of the Literature.
    Open Med (Wars) 2017 29;12:485-488. Epub 2017 Dec 29.
    Department of General Surgery, Fuling Central Hospital of Chongqing City, Chongqing, China.
    Background: Liposarcoma, which develops in adipose tissue, is one of the most common soft tissue sarcomas. It appears mostly in the lower limbs, particularly in the thigh and limb girdles, followed by the upper extremities, thoracoabdominal wall, and the internal trunk and retroperitoneum. Pleomorphic liposarcoma (PLS), a rare subtype of liposarcoma is considered a highgrade malignancy. Read More

    Successful surgical treatment for huge retroperitoneal liposarcoma involving the pancreas, right kidney, abdominal aorta and inferior vena cava.
    J Surg Case Rep 2017 Nov 23;2017(11):rjx200. Epub 2017 Nov 23.
    Department of Surgery, Asahikawa Medical University, Midorigaoka-higashi 2-1-1-1, Asahikawa city, Hokkaido 078-8510, Japan.
    Retroperitoneal liposarcoma is a rare neoplasm that often involves other organs and major blood vessels. Complete surgical resection with negative margins is the only potential curative treatment. Here, we report the case of a patient with a large retroperitoneum liposarcoma that was removed by resection of the descending abdominal aorta and infrahepatic inferior vena cava, right nephrectomy and pancreatoduodenectomy following creation of an extra anatomical femoro-femoral crossover bypass after left axillo-left femoral bypass. Read More

    Gene amplification in mesenchymal stem cells and during differentiation towards adipocytes or osteoblasts.
    Oncotarget 2018 Jan 1;9(2):1803-1812. Epub 2017 Dec 1.
    Department of Human Genetics, Saarland University, 66421 Homburg/Saar, Germany.
    Gene amplifications are an attribute of tumor cells and have for long time been overlooked in normal cells. A growing number of investigations describe gene amplifications in normal mammalian cells during development and differentiation. Possibly, tumor cells have rescued the gene amplification mechanism as a physiological attribute of stem cells. Read More

    Extended surgery using anterior mediastinal tracheostomy for recurrent mediastinal liposarcoma.
    Eur J Cardiothorac Surg 2018 Feb 3. Epub 2018 Feb 3.
    Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
    Mediastinal liposarcoma is an extremely rare malignancy with a poor prognosis. We report the case of a 73-year-old man who presented with severe respiratory distress. He had previously been diagnosed with mediastinal liposarcoma, which had been treated with extirpation 6 years ago. Read More

    Clinicopathologic features and outcomes of primary cardiac tumors: a 16-year-experience with 212 patients at a Chinese medical center.
    Cardiovasc Pathol 2018 Jan 6;33:45-54. Epub 2018 Jan 6.
    Department of Pathology, The Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao 266003, China. Electronic address:
    Primary cardiac tumors are uncommon, and the majority of them are benign which are curable but can cause significant morbidity if not diagnosed and treated in a timely fashion. The objective of this study was to review the clinicopathologic features and surgical outcomes of patients with primary cardiac tumors in a single medical center in China. We have retrospectively reviewed 212 consecutive adult patients who underwent surgical resection of primary cardiac tumors at our center from January of 2001 to June of 2017. Read More

    Eribulin therapy for the treatment of patients with advanced soft tissue sarcoma.
    Future Oncol 2018 Feb 7. Epub 2018 Feb 7.
    Sarcoma Oncology Center, Santa Monica, CA 90403, USA.
    Eribulin is a structurally simplified, synthetic macrocyclic ketone analog of halichondrin B, which is a natural, polyether macrolide derived from marine sponges. Eribulin exerts its cytotoxicity by its unique microtubule dynamics inhibitory action. Eribulin was approved in 2010 by the US FDA as a third-line therapy for metastatic breast cancer patients previously treated with an anthracycline and a taxane. Read More

    Primary Atypical Lipomatous Tumor of the Orbit: A Case Report.
    J Ophthalmic Vis Res 2018 Jan-Mar;13(1):78-80
    Department of Radiology, John H. Stroger, Jr. Hospital of Cook County, Chicago, IL, USA.
    Purpose: To describe a case of primary atypical orbital lipomatous tumor (ALT).

    Case Report: A 35-year-old man presented with a two-month history of left eye proptosis and vertical diplopia. His visual acuity was 20/30 OD and 20/60 OS. Read More

    [A Case of Extrarenal Retroperitoneal Angiomyolipoma].
    Gan To Kagaku Ryoho 2017 Nov;44(12):1346-1348
    Dept. of Surgery, Shuuwa General Hospital.
    We report a rare case of a extrarenal retroperitoneal angiomyolipoma. A 64-year-old female visited our hospital because of an abdominal mass in her lower right abdomen. Enhanced CT scan revealed a 67×52mm tumor in lower right retroperitoneal space. Read More

    [A Case of Retroperitoneal Liposarcoma That Invaded and Filled the Jejunal Lumen].
    Gan To Kagaku Ryoho 2017 Nov;44(12):1338-1340
    Dept. of Gastroenterological Surgery, Kanazawa University.
    A jejunal tumor was found with computed tomography in a 79-year-old man with a history of gastrectomy reconstructed with Billroth II method for gastric ulcers. The tumor with contrast effect extended into the afferent loop and invaded the retroperitoneum in the dorsal side. The tumor occupied the jejunal lumen in endoscopic examination. Read More

    [A Case of a Retroperitoneal Liposarcoma with Long-Term Survival after Four Surgical Resections].
    Gan To Kagaku Ryoho 2017 Nov;44(12):1320-1322
    Dept. of Surgery, Japanese Red Cross Kyoto Daiichi Hospital.
    Retroperitoneal liposarcoma is a relatively rare tumor. The only established therapy is surgical resection and the tumor often recurs. This paper deals with a case of a retroperitoneal liposarcoma in which frequent surgical resections for recurrent tumors have provided relatively long-term survival for the patient. Read More

    [A Case of Retroperitoneal Liposarcoma That Required Three Times Surgical Resections during Four Years].
    Gan To Kagaku Ryoho 2017 Nov;44(12):1158-1160
    Dept. of Surgery, Shizuoka City Shimizu Hospital.
    The patient was a 64-year-old man, who had undergone surgical resection for a right retroperitoneal giant tumor. The histopathological diagnosis was a well-differentiated liposarcoma. Two years and 4 months after the initial surgery, 3 recurrent lesions were found on the dorsal side of the colon hepatic flexure, and resection was performed. Read More

    [Mixed Type Liposarcoma with Intra-Abdominal Bleeding - Report of a Case].
    Gan To Kagaku Ryoho 2017 Nov;44(12):1155-1157
    Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences.
    A 71-year-old man presented with sudden abdominal pain. He had past history of atrial fibrillation, cerebral infarction and heart-valve replacement and received anticoagulant therapy with warfarin. Computed tomography of the abdomen revealed bloody ascites and a huge mass in contact with the third portion of the duodenum. Read More

    Impact of Pathologist Involvement in Sarcoma and Rare Tumor Patient Support Groups on Facebook: A Survey of 542 Patients and Family Members.
    Arch Pathol Lab Med 2018 Jan 29. Epub 2018 Jan 29.
    Context: - Patients with rare tumors have difficulty finding reliable information about their disease. Facebook patient support groups allow patients to educate one another.

    Objective: - To investigate how these patients perceive the value of pathologists, both in Facebook groups and real-world patient care. Read More

    Primary Breast Atypical Lipomatous Tumor/ Well-Differentiated Liposarcoma and Dedifferentiated Liposarcoma.
    Arch Pathol Lab Med 2018 Feb;142(2):268-274
    Atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL) and its higher-grade counterpart, dedifferentiated liposarcoma (DDL), are extraordinarily rare tumors in the breast. The main differential diagnostic consideration of primary breast ALT/WDL is malignant phyllodes tumor with liposarcomatous differentiation, and the main differential diagnostic consideration of DDL in the breast is metaplastic breast carcinoma, particularly the spindle cell type, with heterologous sarcomatous differentiation. These differential diagnoses may be particularly challenging when evaluating limited core needle biopsy sampling. Read More

    1 OF 129