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    MR Imaging of Atraumatic Muscle Disorders.
    Radiographics 2018 Feb 16:170112. Epub 2018 Feb 16.
    From the Department of Radiology, UCSD Medical Center, San Diego, Calif (E.S., M.N.P.); Department of Radiology, Philippine Orthopedic Center, Quezon City, Maria Clara Street, Santa Mesa Heights, Quezon City, Metro Manila, Philippines 1100 (D.V.F.); and Department of Radiology, Hospital Pablo Tobón Uribe, Medellín, Colombia (C.M.G.).
    Atraumatic disorders of skeletal muscles include congenital variants; inherited myopathies; acquired inflammatory, infectious, or ischemic disorders; neoplastic diseases; and conditions leading to muscle atrophy. These have overlapping appearances at magnetic resonance (MR) imaging and are challenging for the radiologist to differentiate. The authors organize muscle disorders into four MR imaging patterns: (a) abnormal anatomy with normal signal intensity, (b) edema/inflammation, (c) mass, and (d) atrophy, highlighting each of their key clinical and imaging findings. Read More

    Expression of MDM2 and p16 in Angiomyolipoma.
    Hum Pathol 2018 Feb 9. Epub 2018 Feb 9.
    Department of Pathology, Hospital for Special Surgery, New York, NY.
    Angiomyolipoma (AML) arises primarily from the kidney, but may grow into the retroperitoneal space mimicking a primary retroperitoneal tumor. Fine needle aspiration (FNA) and core needle biopsy (CNB) of AML, particularly the fat-predominant variant, may be difficult to distinguish from retroperitoneal well-differentiated liposarcoma (WDLS) or lipoma. Commonly used immunomarkers, MDM2 and p16, have proven useful in diagnosing WDLS and dedifferentiated liposarcoma (DDLS), while HMB45 and Melan-A are melanocyte-related markers characteristically expressed in AML. Read More

    J Dtsch Dermatol Ges 2018 Feb 12. Epub 2018 Feb 12.
    Department of Dermatology, Venerology and Allergology, University Medical Center, Göttingen, Germany.
    Lipomatoses are benign proliferations of adipose tissue, often with typical distribution patterns, which usually occur without clear causes. In contrast to circumscribed lipomas, they develop diffusely and symmetrically and are not surrounded by a fibrous pseudocapsule. The most common form is benign symmetric lipomatosis (BSL; Launois-Bensaude syndrome), of which four types are distinguished based on the distribution pattern of hyperplastic adipose tissue. Read More

    Concomitant lipomatous hypertrophy and left atrial mass: Distinguishing benign from malignant.
    Echocardiography 2018 Feb 11. Epub 2018 Feb 11.
    University of Virginia, Charlottesville, VA, USA.
    Masses in and near the interatrial septum may be either benign or malignant. The most common mass near the interatrial septum is lipomatous atrial septal hypertrophy (LASH). LASH can be present in patients with intracardiac malignancies, myxomas, lipomas, or other cardiac masses. Read More

    Intrasynovial spindle cell lipoma of the deep flexor of the middle finger causing intermittent carpal tunnel syndrome-case report and review of the literature.
    J Ultrasound 2018 Feb 10. Epub 2018 Feb 10.
    Department of Musculoskeletal Radiology, The Royal Orthopedic Hospital, Bristol Road South, Northfield, Birmingham, UK.
    Carpal tunnel syndrome (CTS) represents the most common entrapment neuropathy of the upper extremity. Intermittent CTS has been reported in the surgical literature and usually, related to masses associated to flexor tendons. We describe a patient with an intrasynovial lipoma involving the deep flexor of the middle finger causing intermittent CTS and snapping on flexion-extension. Read More

    Spinal arteriovenous fistula coexisting within a spinal lipoma: report of two cases.
    Spinal Cord Ser Cases 2017 14;3:17079. Epub 2017 Nov 14.
    1Department of Orthopedic Surgery, Keio University School of Medicine, Tokyo, Japan.
    Introduction: Spinal lipoma and spinal arteriovenous fistula (sAVF) are different pathologies and their co-existence is extremely rare. Here we reported two cases of adult-onset sAVF occurring within a spinal lipoma and with review the literature in an attempt to identify the mechanisim of and optimal treatment of this condition.

    Case Presentation: Case 1 was a 51-year-old man who was treated by embolization of the feeding artery and ligation of the draining vein. Read More

    Subtle presentation of jejunal lipomata with intussusception in a young adult.
    J Surg Case Rep 2017 Oct 19;2017(10):rjx199. Epub 2017 Oct 19.
    Department of General and Upper Gastrointestinal Surgery, Mid Essex Hospitals Services NHS Trust. Broomfield Hospital, CM1 7ET Essex, UK.
    Lipomas of gastrointestinal (GI) tract could occur at any anatomical level and represent 1-2% of all GI tumours. Amongst them, <2% are noted in jejunum and almost all in later decade of life with varied and non-specific symptoms. Their intussusception is even rarer and mostly present with full obstructive symptoms. Read More

    Asymmetrically enlarged parietal foramina in a rare case of Goldenhar syndrome with a possible etiopathogenesis.
    Oncotarget 2018 Jan 20;9(2):2962-2968. Epub 2017 Dec 20.
    Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.
    Goldenhar´s syndrome (GS) also known as oculo-auriculo-vertebral spectrum (OAVS) is a relatively rare condition. GS is of multifactorial etiology that includes environmental and/or genetic factors, in addition to teratogens that disturb the blastogenesis. A 5-year-old girl from Saudi Arabia, was a member of dizygotic twins conceived by assisted reproductive technology (ART), and born with features of GS. Read More

    Long-term follow-up and novel splice donor mutation inin a Chinese family.
    Oncotarget 2018 Jan 7;9(2):1577-1586. Epub 2017 Dec 7.
    Department of Biochemistry and Molecular Biology, School of Life Sciences, Central South University, Changsha, China.
    Heterozygous germline mutation of thetumor suppressor gene is responsible for multiple endocrine neoplasia type 1. Parathyroid and thoracic neuroendocrine tumor specimens and DNA from two Han Chinese MEN1 family patients were analyzed using whole exome and Sanger sequencing. The proband (II-3) was sequentially diagnosed with pituitary adenoma, pancreatic tumor, adrenal cortical tumor, abdominal lipoma, and parathyroid adenoma during the 6-year follow-up. Read More

    Clinicopathologic features and outcomes of primary cardiac tumors: a 16-year-experience with 212 patients at a Chinese medical center.
    Cardiovasc Pathol 2018 Jan 6;33:45-54. Epub 2018 Jan 6.
    Department of Pathology, The Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao 266003, China. Electronic address:
    Primary cardiac tumors are uncommon, and the majority of them are benign which are curable but can cause significant morbidity if not diagnosed and treated in a timely fashion. The objective of this study was to review the clinicopathologic features and surgical outcomes of patients with primary cardiac tumors in a single medical center in China. We have retrospectively reviewed 212 consecutive adult patients who underwent surgical resection of primary cardiac tumors at our center from January of 2001 to June of 2017. Read More

    Differential Diagnosis of Benign Spindle Cell Lesions.
    Surg Pathol Clin 2018 Mar 9;11(1):91-121. Epub 2017 Dec 9.
    Department of Medical and Surgical Sciences and Advanced Technologies, G.F. Ingrassia, Anatomic Pathology, University of Catania, Via S. Sofia 87, Catania 95123, Italy. Electronic address:
    Spindle cell lesions of the breast cover a wide spectrum of diseases ranging from reactive tumor-like lesions to high-grade malignant tumors. The recognition of the benign spindle cell tumor-like lesions (nodular fasciitis; reactive spindle cell nodule after biopsy, inflammatory pseudotumor/inflammatory myofibroblastic tumor; fascicular variant of pseudoangiomatous stromal hyperplasia) and tumors (myofibroblastoma, benign fibroblastic spindle cell tumor, leiomyoma, schwannoma, spindle cell lipoma, solitary fibrous tumor, myxoma) is crucial to avoid confusion with morphologically similar but more aggressive bland-appearing spindle cell tumors, such as desmoid-type fibromatosis, low-grade (fibromatosis-like) spindle cell carcinoma, low-grade fibrosarcoma/myofibroblastic sarcoma and dermatofibrosarcoma protuberans. Read More

    Diagnostic Dilemma: Cerebellopontine Angle Lipoma Versus Dermoid Cyst.
    Cureus 2017 Nov 30;9(11):e1894. Epub 2017 Nov 30.
    Department of Neurological Surgery, Houston Methodist Hospital.
    Both lipomas and dermoid cysts of the cerebellopontine angle are rare tumors. These tumors differ in their embryological origin but share similar features on imaging. Both of these congenital lesions can be found in the cerebellopontine angle (CPA), and symptomatic clinical presentation is dictated by the location of the lesion. Read More

    Transoral robotic surgery of parapharyngeal space tumours: a series of four cases.
    Int J Oral Maxillofac Surg 2018 Jan 31. Epub 2018 Jan 31.
    Maxillofacial-ENT Surgery Unit, Istituto Nazionale Tumori "Fondazione G. Pascale" - IRCCS, Napoli, Italy.
    Tumours arising from the parapharyngeal space (PPS) represent less than 1% of all head and neck tumours. Salivary gland tumours account for 40-50% of PPS lesions and are located in the pre-styloid parapharyngeal space. Pleomorphic adenomas represent 80-90% of salivary tumours in the PPS. Read More

    Spontaneous peeled ileal giant lipoma caused by lower gastrointestinal bleeding: A case report.
    Medicine (Baltimore) 2017 Dec;96(51):e9253
    Department of Internal Medicine, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon.
    Rationale: Gastrointestinal subepithelial tumors (SETs) with endoscopic features such as ulceration, a red color change, a peeled mucosal layer, and spontaneous bleeding could have malignant potential. However, we encountered a case of a lipoma that presented features different from the generally known features of gastrointestinal SETs. Therefore, we report an interesting rare case of a terminal ileal giant lipoma with a unique feature of spontaneous peeled ulceration on the surface on endoscopy that caused gastrointestinal bleeding. Read More

    Liponeurofibroma: Clinicopathological features and histogenesis.
    J Dermatol 2018 Jan 31. Epub 2018 Jan 31.
    Department of Dermatology, Yonsei University Wonju College of Medicine, Wonju, Korea.
    A neurofibroma is a common cutaneous benign tumor of neural origin. Various histological variants have been reported. Recently, sporadic reports of fatty variants have been reported but their clinicopathological features have not been well studied. Read More

    Giant Parapharyngeal Space Lipoma Extending to the Pterygoid Region (Anterior Skull Base).
    J Craniofac Surg 2018 Jan 19. Epub 2018 Jan 19.
    Department of Obstetrics and Gynecology. Apollo Institute of Medical Sciences, Hyderabad, India.
    Although lipoma is frequently seen in the head and neck region, but occurrence of the lipoma in the parapharyngeal space is rare. It is extremely rare for a parapharyngeal lipoma to extent to the pterygoid region (ie, anterior skull base). Management of giant parapharyngeal space lipoma with skull base extension and proximity to the vital neurovascular structures poses a challenge to surgeon. Read More

    How to Explore Fetal Sacral Agenesis Without Open Dysraphism: Key Prenatal Imaging and Clinical Implications.
    J Ultrasound Med 2018 Jan 27. Epub 2018 Jan 27.
    Department of Obstetrics and Gynecology, Hospital Antoine Béclère, Assistance Publique-Hôpitaux de Paris, Université Paris Sud, Paris, France.
    The estimated prevalence of fetal caudal dysgenesis is 1 per 100,000 births. The functional prognosis of sacral agenesis is dominated by the large spectrum of associated caudal malformations. Except for cases associated with hydrocephalus secondary to open spinal dysraphism or chromosomal anomalies, association with mental deficiency is rare. Read More

    A case report with sacral appendage: Is it accessory penis or human tail?
    Turk J Pediatr 2017 ;59(3):335-337
    Department of Pathology, Konya Education and Research Hospital, Konya, Turkey.
    Kocaoğlu C, Kocaoğlu Ç, Akkoyun İ, Karaniş İE. A case report with sacral appendage: Is it accessory penis or human tail? Turk J Pediatr 2017; 59: 335-337. Lumbo-sacro-coccygeal appendages are very rare congenital anomalies. Read More

    Chest wall - a structure underestimated in ultrasonography. Part III: Neoplastic lesions.
    J Ultrason 2017 Dec 29;17(71):281-288. Epub 2017 Dec 29.
    Self-education Sonography Group, Genetics Division, Pomeranian Medical University, Szczecin, Poland.
    Chest wall neoplasms mainly include malignancies, metastatic in particular. Differential diagnosis should include clinical data; tumor location, extent, delineation; the degree of homogeneity; the presence of calcifications; the nature of bone destruction and the degree of vascularization. The aim of the paper is to present both the benefits and limitations of ultrasound for the diagnosis of chest wall neoplasms. Read More

    Gastric Lipoma: A Review of the Literature.
    Ultrasound Q 2018 Jan 23. Epub 2018 Jan 23.
    Gastric lipoma is a rare benign tumor of the stomach. The imaging characteristics are diagnostic because the lesion has fat attenuation on computed tomography and demonstrates characteristics of fat on magnetic resonance images. On ultrasound, the lesion can be identified as a lesion hypoechoic to the gastric mucosa that is soft, but the mass cannot be displaced with compression. Read More

    Minimally Invasive Surgical Approach to Filum Lipoma.
    Neurol Med Chir (Tokyo) 2018 Jan 23. Epub 2018 Jan 23.
    Department of Neurosurgery, Tohoku University Graduate School of Medicine.
    Filum terminale lipoma (FTL) causes various spinal symptoms known as tethered cord syndrome. The treatment for FTL is surgical untethering by sectioning the FTL, which can prevent symptom progression and often results in improvement of symptoms. This report describes a minimally invasive surgical strategy that we have introduced for FTL sectioning. Read More

    Tumours composed of fat are no longer a simple diagnosis: an overview of fatty tumours with a spindle cell component.
    J Clin Pathol 2018 Jan 22. Epub 2018 Jan 22.
    Department of Pathology, Laboratory Medicine Program, University Health Network, University of Toronto, Toronto, Canada.
    This is a review of the morphological spectrum of fatty tumours containing a component of spindle cells, highlighting the immunohistochemical and cytogenetic workup that is now mandatory for accurate diagnosis, with the goal of providing a practical approach for practising surgical pathologists. There have been significant advances in recent years in classifying and understanding the pathogenesis of fatty tumours with spindle cells, based on the correlation of histological, immunohistochemical and cytogenetic/molecular findings. In spite of this, morphological diagnosis and accurate classification of fatty tumours with spindle cells can be challenging to diagnostic pathologists. Read More

    A rare location for a common tumor: Lingual lipoma.
    J Stomatol Oral Maxillofac Surg 2018 Jan 17. Epub 2018 Jan 17.
    Service de chirurgie maxillo-faciale et stomatologie, CHU d'Angers, 4 rue Larrey, 49933 Angers Cedex, France. Electronic address:
    Lipomas are the most common benign tumors in human body but their occurrence in the oral cavity is very rare. They present as a slow growing, yellowish submucosal and painless mass. The treatment consists of a simple surgical excision. Read More

    Unusual complications caused by lipoma of the tongue.
    J Korean Assoc Oral Maxillofac Surg 2017 Dec 27;43(Suppl 1):S6-S8. Epub 2017 Dec 27.
    Department of Dentistry, University of Siena, Siena, Italy.
    Lipoma is the most common, benign, soft tissue, mesenchymal tumour and is composed of mature adipose tissue. It is infrequent in the oral cavity (approximately 0.3% of all tongue neoplasias). Read More

    The Pathology of Lumbosacral Lipomas: Macroscopic and Microscopic Disparity Have Implications for Embryogenesis and Mode of Clinical Deterioration.
    Histopathology 2018 Jan 19. Epub 2018 Jan 19.
    Developmental Biology and Cancer Programme, UCL Institute of Child Health, 30 Guildford Street, London, WC1N 1EH.
    Aims: Lumbosacral lipomas (LSL) are congenital disorders of the terminal spinal cord region that have the potential to cause significant spinal cord dysfunction in children. They are of unknown embryogenesis with variable clinical presentation and natural history. It is unclear whether the spinal cord dysfunction reflects a primary developmental dysplasia or whether it occurs secondarily to mechanical traction (spinal cord tethering) with growth. Read More

    [Intraosseous lipoma: retrospective analysis of 19 patients].
    Zhongguo Gu Shang 2017 Mar;30(3):279-281
    Department of Orthopeadics, Gansu Provincial Hospital, Lanzhou 730000, Gansu, China.
    Objective: To investigate the diagnostic and therapeutic procedures of intraosseous lipoma.

    Methods: From June 1986 to January 2016, 19 patients with intraosseous lipoma were treated including 12 males and 7 females, aged from 24 to 76 years, a predilection aged was from 40 to 50 years in 13 cases. Symptoms presented with pain or swelling in 15 patients, the lesions were found incidentally in 3 patients, another case was bone defect lipoma replacement after curettage of bone cyst for 4 years. Read More

    Aggressive Resection of Congenital Lumbosacral Lipomas in Adults: Indications, Techniques, and Outcomes in 122 Patients.
    World Neurosurg 2018 Jan 11. Epub 2018 Jan 11.
    Department of Neurosurgery, PLA General Hospital, Haidian District, Beijing, China. Electronic address:
    Objective: The authors reviewed the treatment of adult patients with congenital intraspinal lipomas with total/near-total resection and discussed their preoperative characteristics, prognostic factors, and surgical outcomes.

    Methods: Medical records of 122 adult patients with congenital lumbosacral lipomas undergoing total/near-total resection were systematically analyzed. The cohort was subdivided into 3 groups depending on symptom onset age: group 1 (≤5 years, n = 40), group 2 (>5 years but <18 years, n = 33), and group 3 (>18 years, n = 49). Read More

    Efficiency of Imaging Modalities in Male Breast Disease: Can Ultrasound Give Additional Information for Assessment of Gynecomastia Evolution?
    Eur J Breast Health 2018 Jan 1;14(1):29-34. Epub 2018 Jan 1.
    Department of Radiology, Taksim Gaziosmanpaşa Training and Research Hospital, İstanbul, Turkey.
    Objective: The purpose of this study is to present mammography and ultrasound findings of male breast lesions and to investigate the ability of diagnostic modalities in estimating the evolution of gynecomastia.

    Materials And Methods: Sixty-nine male patients who admitted to Taksim and Bakirkoy Education and Research Hospitals and underwent mammography (MG) and ultrasonography (US) imaging were retrospectively evaluated. Duration of symptoms and mammographic types of gynecomastia according to Appelbaum's classifications were evaluated, besides the sonographic findings in mammographic types of gynecomastia. Read More

    A rare case of bronchial elastosis: An unusual presentation of an unexpandable lung.
    Lung India 2018 Jan-Feb;35(1):50-53
    SUNY Downstate Medical Center; Department of Pulmonary and Critical Care Medicine, VA Hospital, Brooklyn, New York, USA.
    Endobronchial obstruction is a known cause of an unexpandable lung. Endobronchial lesions are usually malignant, however benign cause like hemartoma, lipoma, amyloidosis and neuroendocrine tumors are known. We, hereby present the rare cause of bronchial elastosis presenting as right lower lobe lung collapse. Read More

    [Benign mesenchymal tumors of the abdomen].
    Radiologe 2018 Jan;58(1):25-35
    FE MRT, Radiologische Universitätsklinik Bonn, Sigmund-Freud-Straße 25, 53127, Bonn, Deutschland.
    Background: Benign mesenchymal tumors of the abdomen are-except for hemangiomas-rare neoplasms that are associated with potentially life-threatening complications. Thus, awareness of the most important entities and knowledge of their imaging characteristics is fundamental for the radiologist.

    Objectives: An overview of the most frequent benign abdominal soft tissue tumors and their common imaging features is given. Read More

    Ultrasonographic assessment of male breast diseases.
    Breast J 2018 Jan 8. Epub 2018 Jan 8.
    Department of Diagnostic Ultrasound, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
    Although rare and accounting for less than 1% of all breast cancers, the incidence of breast cancer in men has increased by 26% over the past few decades. Very little has been reported on the sonographic appearance of benign and malignant male breast conditions. The aim of this study was to describe the ultrasonographic features of male breast disease and the value of ultrasound in the evaluation of male breast disease. Read More

    The management of deep-seated, lowgrade lipomatous lesions.
    Br J Radiol 2018 Jan 17:20170725. Epub 2018 Jan 17.
    1 Radiology Department, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield , United Kingdom.
    Deep-seated, low-grade lipomatous lesions detected on imaging often cause uncertainty for diagnosis and treatment. Confidently distinguishing lipomas from well-differentiated liposarcomas is often not possible on imaging. The approach to management of such lesions varies widely between institutions. Read More

    Large Subpectoral Lipoma on Screening Mammography.
    J Radiol Case Rep 2017 Sep 30;11(9):22-27. Epub 2017 Sep 30.
    Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, USA.
    A 61 year-old woman presenting for bilateral screening mammogram was found to have an oval fat-density mass in the posterior right breast, partially visualized, with anterior displacement and thinning of the pectoralis major muscle. This mass was found on CT and MRI correlation to represent a large fat-containing mass, likely a lipoma, deep to the pectoralis major. On subsequent screening mammograms, the visualized portion of the mass remained stable. Read More

    [Dendritic infraclavicular fibromyxolipoma: At the boundary between spindle cell lipoma and solitary fibrous tumour].
    Rev Esp Patol 2018 Jan - Mar;51(1):44-48. Epub 2017 Mar 2.
    Servicio de Anatomía Patológica, Hospital Infanta Margarita, Cabra, Córdoba, España.
    Dendritic fibromyxolipoma (DFML) is a rare soft tissue tumor recently described with only 27 cases reported in the literature. None of them have shown recurrence or metastasis after excision. Histologically it is composed of small stellate or spindle cells in a myxoid stroma with abundant collagen bundles mixed with mature adipose tissue. Read More

    [Nevus lipomatosus cutaneous superficialis. Report of four cases including an unusual presentation associated with massive lipomas and diffuse lipomatosis].
    Rev Esp Patol 2018 Jan - Mar;51(1):37-43. Epub 2017 Jul 29.
    Departamento de Cirugía, Hospital General Docente Enrique Cabrera, La Habana, Cuba.
    Nevus lipomatosus cutaneus superficialis is a rare, hamartomatous disorder, characterized by the presence of ectopic mature adipose tissue within the superficial dermis. Lesions occur within the first three decades of life. We report four new cases, including a patient with the most extensive affectation reported to date, which was associated with massive lipomas in the subcutaneous cell tissue and diffuse lipomatosis. Read More

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