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    1 OF 299

    [Spindle cell lipoma and pleomorphic lipoma: a clinicopathologic analysis of 65 cases].
    Zhonghua Bing Li Xue Za Zhi 2018 Apr;47(4):263-268
    Department of Pathology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China.
    To investigate the clinical and pathological features of spindle cell lipoma (SCL) and pleomorphic lipoma (PL) with emphasis on differential diagnosis. Sixty-five cases of SCL/PL from the archive of Department of Pathology, Fudan University Shanghai Cancer Center, from August of 2006 to June of 2017, were included in the study. Immunohistochemistry by EnVision method, MDM2 gene amplifycation and DDIT3 gene translocation by fluorescence in situ hybridization(FISH) were detected and the literature was reviewed. Read More

    Whole blood miRNA expression analysis reveals miR-3613-3p as a potential biomarker for dedifferentiated liposarcoma.
    Cancer Biomark 2018 Apr 9. Epub 2018 Apr 9.
    Clinic for Plastic and Hand Surgery, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
    Background: Liposarcoma constitute about 13% of all soft tissue sarcoma and are associated with a high risk of metastases. As the preoperative differentiation between benign and malign lipomatous tumors is restricted to magnetic resonance imaging, computed tomography and biopsy, we performed a miRNA array to distinguish dedifferentiated liposarcoma patients from healthy controls and lipoma patients.

    Methods: Blood samples of patients with dedifferentiated liposarcoma, healthy controls and lipoma patients were collected. Read More

    Madelung's Disease: Lipectomy or Liposuction?
    Biomed Res Int 2018 21;2018:3975974. Epub 2018 Feb 21.
    Department of Plastic Surgery, The Fourth Affiliated Hospital, College of Medicine, Zhejiang University, Yiwu, Zhejiang, China.
    Background: Madelung's disease is a rare lipid metabolic disorder characterized by diffuse, uncapsulated lipomas in the neck, shoulder, and other areas. It mainly affects middle-aged men and is related to alcohol abuse, and the cause is not clear. Surgical treatments include lipectomy and liposuction. Read More

    Acute communicating hydrocephalus as spinal cord surgery complication in a patient with lumbar lipomyelocele. Case report.
    World Neurosurg 2018 Apr 17. Epub 2018 Apr 17.
    Department of Neurosurgery, Istituto Giannina Gaslini, via Gaslini 5, 16147 Genoa, Italy.
    Background: A lumbar lipomyelocele is a closed spinal dysraphism that can cause tethered cord syndrome. Between 5-15% of spinal dysraphism surgery cases are burdened with complications, the most common being wound infections or dehiscence and cerebrospinal fluid leak. Acute communicating hydrocephalus has never been described as a complication of this type of surgery. Read More

    Simultaneous Median and Ulnar Compression Neuropathy Secondary to a Giant Palmar Lipoma: A Case Report and Review of the Literature.
    Cureus 2018 Feb 16;10(2):e2198. Epub 2018 Feb 16.
    Department of Orthopaedics and Traumatology, University of Health Sciences, Medical Faculty, Antalya Education and Research Hospital, Antalya, Turkey.
    Lipomas are benign tumors that rarely settle in the hand. They usually present with mass, pain, and nerve compression symptoms. Although isolated median or ulnar nerve compression neuropathy secondary to a lipoma of the hand has been widely reported, simultaneous median and ulnar nerve compression neuropathy are exceedingly rare and there are only three reported cases in the current literature to date. Read More

    Mental Development and Surgical Prognosis of Pai Syndrome: A Case Report and Review of the Literature.
    Cleft Palate Craniofac J 2018 Jan 1:1055665618771419. Epub 2018 Jan 1.
    1 Department of Plastic and Reconstructive Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
    Pai syndrome is a rare congenital disorder, and there are few reports about the long-term prognosis of mental development and surgical results. Here, we report a patient with Pai syndrome who was followed up from birth up to the age of 8 years. Additionally, we review 32 articles and discuss the long-term prognosis of Pai syndrome. Read More

    Fibrolipoma on a Child's Lip: A Rare Clinical Finding.
    J Dent Child (Chic) 2018 Jan;85(1):36-39
    Department of Oral and Maxillofacial Pathology, STES Sinhgad Dental College and Hospital, Pune, Maharashtra, India.
    Lipoma is very common benign tumor of adipose tissue, but its presence in the oral cavity is rare. Fibrolipoma is a histological variant of lipoma that affects the buccal mucosa and nasal septum in the orofacial region and causes functional and cosmetic issues. However, this lesion has not been reported on the upper lip and may be confused with other soft tissue lesions of children. Read More

    EZH2 Expression in Naturally Occurring Canine Tumors.
    Comp Med 2018 Apr;68(2):148-155
    University of Ulsan College of Medicine, Asan Institute for Life Sciences, and Department of Pathology, Asan Medical Center, Seoul, Korea., Email:
    Enhancer of zeste homolog 2 (EZH2) shows upregulated expression in tumors and is an important driver of tumor development and progression. However, the mechanism underlying the mediation of tumor aggressiveness by EZH2 remains unclear. We here investigated the levels of EZH2 in various normal and tumorous dog tissues and compared these patterns with those of the corresponding human tissues. Read More

    Liposarcoma Preoperatively Diagnosed as Lipoma: 10-Year Experience at a Single Institution.
    Dermatol Surg 2018 Apr 13. Epub 2018 Apr 13.
    Department of Plastic Surgery, Kyorin University School of Medicine, Tokyo, Japan.
    Background: On rare occasions, a lesion preoperatively diagnosed as a lipoma is ultimately diagnosed as a liposarcoma. It is important to differentiate liposarcomas from lipomas preoperatively.

    Objective: To examine characteristic features of liposarcomas preoperatively diagnosed as lipomas. Read More

    A rare case of gint lipomatous hypertrophy of the atrial septum.
    Acta Biomed 2018 Mar 27;89(1):114-116. Epub 2018 Mar 27.
    Cardiac Surgery Unit, Parma General Hospital, Parma, Italy.
    Benign lipomatous lesion of the heart includes  an heterogeneous group of entities including neoplastic, congenital and reparative phenomena. Among these lipomas and lipomatous hypertrophy of the atrial septum ( LHIS) represent the most common lesion. Patients suffering from LHIS are often asymptomatic, however atrial fibrillation, congestive heart failure and supraventricular tachycardia are typical findings. Read More

    Magnetic resonance imaging (MRI) of the renal sinus.
    Abdom Radiol (NY) 2018 Apr 9. Epub 2018 Apr 9.
    Department of Radiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
    This article presents methods to improve MR imaging approach of disorders of the renal sinus which are relatively uncommon and can be technically challenging. Multi-planar Single-shot T2-weighted (T2W) Fast Spin-Echo sequences are recommended to optimally assess anatomic relations of disease. Multi-planar 3D-T1W Gradient Recalled Echo imaging before and after Gadolinium administration depicts the presence and type of enhancement and relation to arterial, venous, and collecting system structures. Read More

    EZH2 Expression in Naturally Occurring Canine Tumors.
    Comp Med 2019 Mar;68(2):148-155
    University of Ulsan College of Medicine, Asan Institute for Life Sciences, and Department of Pathology, Asan Medical Center, Seoul, Korea;, Email:
    Enhancer of zeste homolog 2 (EZH2) shows upregulated expression in tumors and is an important driver of tumor development and progression. However, the mechanism underlying the mediation of tumor aggressiveness by EZH2 remains unclear. We here investigated the levels of EZH2 in various normal and tumorous dog tissues and compared these patterns with those of the corresponding human tissues. Read More

    Accessory scrotum and congenital perineal lipoma in a child with type 2 congenital pulmonary airway malformation: A report of an unusual.
    Int J Health Sci (Qassim) 2018 Jan-Feb;12(1):85-86
    Department of Pathology and Laboratory Medicine, King Saud University and King Khalid University Hospital, Riyadh, KSA.
    Accessory scrotum and congenital perineal lipoma are unusual congenital anomalies. Congenital pulmonary airway malformation (CPAM) is a rare congenital disorder of the lung. There are five types of CPAM, each with a different clinical presentation and prognosis. Read More

    Imaging of Benign Neoplastic and Nonneoplastic Salivary Gland Tumors.
    Neuroimaging Clin N Am 2018 May;28(2):159-169
    Department of Radiology, University of Chicago, Pritzker School of Medicine, 5841 South Maryland Avenue, Chicago, IL 60637, USA. Electronic address:
    This article reviews the multimodality diagnostic imaging features of benign neoplastic and nonneoplastic tumors associated with the major salivary glands. Examples of neoplastic conditions that are depicted and discussed include pleomorphic adenoma, Warthin tumor, oncocytoma, peripheral nerve sheath tumors, lipoma, and hemangiomas or hemangioendotheliomas. Examples of nonneoplastic conditions that are depicted and discussed include ranulas, benign lymphoepithelial lesions, Kimura disease, and vascular malformations. Read More

    Spindle Cell Lipoma of the Thumb.
    Plast Reconstr Surg Glob Open 2018 Feb 9;6(2):e1671. Epub 2018 Feb 9.
    Department of Plastic and Reconstructive Surgery, Kawasaki Medical School, Okayama, Japan.
    We report the case of a 34-year-old man who presented with a 4-year history of a soft tissue on the palmar aspect of the thumb. Magnetic resonance imaging demonstrated the presence of a mass with heterogeneous high intensities on T1-weighted images and high intensities on T2-weighted images. We performed excisional biopsy. Read More

    Subcutaneous lipomas: A minimally invasive method for resection of subcutaneous lipomas preserving retaining ligaments.
    Eur J Plast Surg 2018 9;41(2):173-176. Epub 2017 Jun 9.
    Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Shogoin, Kawahara-cho 54, Sakyo-ku, Kyoto, 606-8507 Japan.
    Background: Lipomas are common benign tumors usually located in the subcutaneous tissues. Resection of lipomas frequently requires incisions equal to the diameter of the tumor. The "squeeze technique" with a small incision is well-described, but is frequently not successful, particularly for lipomas in the shoulder region. Read More

    Preoperative radiologic patent blue localization for intracorporeal laparoscopic resection of a terminal ileal submucosal lipoma: A case report.
    Int J Surg Case Rep 2018 Mar 15;45:91-95. Epub 2018 Mar 15.
    Department of General Surgery, No. 5, Fuxing St., Guishan Dist., Taoyuan City 33305, Taiwan; Department of Surgery, Xiamen Chang Gung Hospital, Xiamen, Fujian, China. Electronic address:
    Background: Ileal submucosal lipomas are rare cases and surgical intervention was necessary in case of abdominal pain and intussusception. Laparoscopic resection may be difficult for the intraluminal submucosal lesion. Herein, we report a case of terminal ileal submucosal lipoma resected by radiologic-assisted laparoscopic surgery. Read More

    A case of junctional neural tube defect associated with a lipoma of the filum terminale: a new subtype of junctional neural tube defect?
    J Neurosurg Pediatr 2018 Mar 30:1-5. Epub 2018 Mar 30.
    Departments of 1 Pediatric Neurosurgery.
    The embryological development of the central nervous system takes place during the neurulation process, which includes primary and secondary neurulation. A new form of dysraphism, named junctional neural tube defect (JNTD), was recently reported, with only 4 cases described in the literature. The authors report a fifth case of JNTD. Read More

    An Intramuscular Chondrolipoma of the Scapula: A Case Report of a Rare Tumor in an Unusual Location.
    J Orthop Case Rep 2017 Nov-Dec;7(6):64-67
    Department of Orthopedics, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC.
    Introduction: Chondrolipomas are rare benign mesenchymal tumors primarily occurring in the shoulder region. To the best of our knowledge, only one case of chondrolipoma arising from the shoulder has been reported. We herein report an intramuscular chondrolipoma located in an unusual area of the scapula. Read More

    Placode rotation in transitional lumbosacral lipomas: are there implications for origin and mechanism of deterioration?
    Childs Nerv Syst 2018 Mar 29. Epub 2018 Mar 29.
    Great Ormond Street Institute of Child Health, 30 Guildford Street, London, WC1N 1EH, UK.
    Purpose: Rotation of the lipoma-neural placode has been noted in transitional lumbosacral lipomas. The purpose of this study was to confirm this rotation; that this rotation occurs with a preference to the left, and correlates with clinical symptoms. In addition, this study tests the hypothesis that this rotation occurs through local mechanical forces rather than intrinsic congenital malformation. Read More

    The feasibility of shear wave elastography for diagnosing superficial benign soft tissue masses.
    Ultrasonography 2018 Jan 19. Epub 2018 Jan 19.
    Department of Radiology, Hanyang University Guri Hospital, Guri, Korea.
    Purpose: The purpose of this study was to investigate the feasibility of shear wave ultrasound elastography for differentiating superficial benign soft tissue masses through a comparison of their shear moduli.

    Methods: We retrospectively analyzed 48 masses from 46 patients from February 2014 to May 2016. Surgical excision, fine-needle aspiration, and clinical findings were used for the differential diagnosis. Read More

    Common and Uncommon Benign Pancreatic Lesions Mimicking Malignancy: Imaging Update and Review.
    Semin Ultrasound CT MR 2018 Apr 26;39(2):206-219. Epub 2017 Oct 26.
    Grupo Fleury, São Paulo, Brazil; Department of Imaging, Universidade Federal de São Paulo, São Paulo, Brazil.
    There is a broad range of inflammatory, pseudotumoral, and benign lesions that may masquerade as pancreatic malignancies, often representing a challenge to the radiologist. Unawareness of these entities can lead to inadequate differential diagnoses or misdiagnosis, with important prognostic and therapeutic consequences. The purpose of this article is to revisit a spectrum of lesions, varying from common to exceedingly rare nonmalignant, that may mimic malignant pancreatic neoplasms on imaging, identifying relevant features that may contribute to reaching the correct diagnosis. Read More

    Simvastatin induces apoptosis in PTEN‑haploinsufficient lipoma cells.
    Int J Mol Med 2018 Jun 14;41(6):3691-3698. Epub 2018 Mar 14.
    University Hospital for Children and Adolescents, Center for Pediatric Research Leipzig (CPL), D‑04103 Leipzig, Germany.
    Adipose tissue tumors (lipomas) frequently develop in patients with heterozygous germ line phosphatase and tensin homolog (PTEN) mutations. simvastatin has been demonstrated to exhibit antitumor effects, and so the aim of the present study was to assess the effects of simvastatin on the growth of human PTEN haploinsufficient lipoma cells. Whether the effects of simvastatin in lipomas are mediated via PTEN upregulation was also assessed. Read More

    Medical image analysis of knee joint lipoma arborescens and arthroscopic treatment.
    Comput Med Imaging Graph 2018 Jun 12;66:66-72. Epub 2018 Jan 12.
    Rehabilitation Medicine Department, China-Japan Friendship Hospital, Beijing, China. Electronic address:
    Objective: Arthroscopy is a minimally invasive surgical procedure on a joint in which examination and treatment of knee damage is performed using a surgical device known as the arthroscope. Lipoma arborescens (LA), an infrequent intra-articular lesion, originates from mature adipose cells under subsynovial tissue. The synovial membrane is pale yellow with large villous projections. Read More

    Intramuscular Hibernoma of the Scapular Region Misdiagnosed on Cytology as a Malignant Lesion: A Report of a Rare Case.
    Iran J Pathol 2017 1;12(4):406-409. Epub 2017 Oct 1.
    Department of Oncosurgery, RJSP Cancer Hospital, Ranchi, India.
    Hibernomas are extremely rare benign tumors of adipose tissue characterized by an admixture of brown fat cells with granular, multivacuolated cytoplasm and white fat cells. Hibernomas account for 1.6% of benign adipose tissue tumors and approximately 1. Read More

    [Clinical experience in diagnosis and treatment of primary retroperitoneal liposarcoma].
    Zhonghua Yi Xue Za Zhi 2018 Mar;98(10):773-776
    Department of Urology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
    To summarize the experience in diagnosis and treatment of primary retroperitoneal liposarcoma. The clinic data of 73 cases of primary retroperitoneal liposarcoma were reviewed. The age of patients was 23 to 75 years old, with a median age of 53 years. Read More

    [Pai syndrome: Two new cases with unusual manifestations].
    Arch Argent Pediatr 2018 Apr;116(2):e336-e340
    Servicio de Genética, Hospital de Pediatría Garrahan, Ciudad Autónoma de Buenos Aires, Argentina.
    Pai syndrome is a very rare congenital disorder characterized by medial cleft lip, nasal and facial cutaneous polyps, and pericallosal lipoma. Broad phenotypic variability exists in this condition. Neurodevelopment is usually normal. Read More

    Cardiac Lipoma: An Uncharacteristically Large Intra-Atrial Mass Causing Symptoms.
    Case Rep Cardiol 2018 6;2018:3531982. Epub 2018 Feb 6.
    Southern Illinois Heart and Vascular Center, 4115 S. Water Tower Place, Mount Vernon, IL 62864, USA.
    Primary tumours of the heart are often encountered in clinical practice. Different autopsy series estimate the incidence to be anywhere from 0.001% to 0. Read More

    Lipoma of the transverse colon covered by tubulovillous adenoma: a rare indication for surgical treatment.
    G Chir 2018 Jan-Feb;39(1):63-66
    Lipomas of the digestive tract are rare benign tumours which, in most cases, are totally asymptomatic. Because of their localization within the intestinal wall, endoscopy may be completely negative so contrast-enhanced computed tomography (CT) is very important for detecting and typing these lesions. The case of a 49-year-old man with abdominal pain is presented. Read More

    Granular Cell Tumor: Report of 13 Cases in a Veterans Administration Hospital.
    Mil Med 2018 Mar 14. Epub 2018 Mar 14.
    Department of Surgery, Gulf Coast Veterans Health Care System, Biloxi, MS 39531.
    Introduction: Granular cell tumors (GCTs) are of neuroectodermal origin and account for 0.5% of soft tissue tumors. They are most prevalent in African-Americans in the fourth to sixth decades, with a predilection for the head and neck regions. Read More

    Partial spontaneous anal expulsion of the right colon lipoma: An exceptional diagnostic circumstance.
    Int J Surg Case Rep 2017 15;41:414-416. Epub 2017 Nov 15.
    Department of Digestive Surgery, Farhat Hached University Hospital, Sousse, Tunisia. Electronic address:
    Introduction: Lipomas are most common benign tumors of the colon. They are asymptomatic and fortuitously discovered on a morphological examination. Rarely, they cause complications such as acute intussusception. Read More

    Biodynamic excisional skin tension lines for surgical excisions: untangling the science.
    Ann R Coll Surg Engl 2018 Apr 15;100(4):330-337. Epub 2018 Mar 15.
    University of Queensland, School of Medicine , Brisbane, Queensland , Australia.
    Objective There remains confusion between Langer's lines and wrinkle lines with respect to the optimal orientation of elliptical excisions on the trunk. This study sought to determine the directions of wound closure that would result in least wound tension after skin lesion excisions. Materials and methods Some 1181 consecutive skin lesion excisions were investigated (age range 13-95 years, median 64 years) using a tensiometer to determine directions of least wound tension. Read More

    Liposarcoma of the spermatic cord associated with scrotum lipoma: A case report and review of the literature.
    Urol Case Rep 2018 Mar 2;17:114-116. Epub 2018 Feb 2.
    Osaka Rosai Hospital, Japan.
    Liposarcoma of the spermatic cord is a rare disease and often mistakenly diagnosed as inguinal hernia, hydrocele, and lipoma. We report the case of a 58-year-old man who presented with persistent discomfort and swelling on the left inguinal region. He was diagnosed with left scrotum lipoma when he was 12 years old. Read More

    [Adrenal myelolipoma: about a case].
    Pan Afr Med J 2017 18;28:153. Epub 2017 Oct 18.
    Service d'Endocrinologie Diabétologie Maladies Métaboliques et Nutrition, Laboratoire PCIM, FMPM, Université Cadi Ayyad, CHU Mohamed VI, Marrakech.
    Adrenal myelolipoma is a rare benign non secreting tumor. It is often unexpectedly detected. Pathophysiologically, it is adrenal cortex cell metaplasia into reticuloendothelial cells, resulting from infection, chronic stress or adrenal gland degeneration. Read More

    [Lipofibromatosis: a clinicopathological analysis of eight cases].
    Zhonghua Bing Li Xue Za Zhi 2018 Mar;47(3):186-191
    Department of Pathology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China.
    To investigate the clinicopathological characteristics and differential diagnosis of lipofibromatosis. The clinicopathological features and immunohistochemical profiles in 8 cases of lipofibromatosis diagnosed at Fudan University Shanghai Cancer Center from January 2008 to June 2017 were studied. Molecular analysis of β-catenin mutation by Sanger sequencing, NTKR1 and ETV6 rearrangements by FISH were performed. Read More

    [Giant lipoma of the thigh. Case report].
    Acta Ortop Mex 2017 Sep-Oct;31(5):248-251
    Hospital Ángeles Lomas. Ciudad de México. México.
    Lipoma is a tumor of adipose tissue cells that can develop in any part of the body; We present the case of an 86-year-old woman with a lesion of the left thigh as well as her diagnostic approach, specific surgical treatment and histopathological analysis. Three years after its resection, the function of the lower extremity was preserved. Read More

    The application value of capsule endoscopy in diagnosing small intestinal carcinoma.
    J Cancer Res Ther 2018 Jan;14(1):57-60
    Department of Endoscopy, Xinxiang Central Hospital, Henan Province, PR China.
    Objective: The aim of this study was to explore the clinical value of capsule endoscopy in the diagnosis of small intestine neoplastic lesions.

    Materials And Methods: A retrospective analysis was conducted on the clinical data of 108 patients who underwent capsule endoscopic examination in the Endoscopy Center of Xinxiang Central Hospital from February 2010 to January 2014. The characteristics of different small bowel diseases were observed, and the prevalence rates of different small bowel lesions were calculated. Read More

    [Lipoblastoma detected in older children: an unusual case and literature review].
    Pan Afr Med J 2017 6;28:119. Epub 2017 Oct 6.
    Service de Traumato-orthopédie Pédiatrique, CHU-Hassan II, Fès, Maroc.
    Lipoblastoma is a relatively rare benign tumor. It derives from embryonic white fat cells. It almost exclusively affects children less than 3 years of age. Read More

    Fatty Images of the Heart: Spectrum of Normal and Pathological Findings by Computed Tomography and Cardiac Magnetic Resonance Imaging.
    Biomed Res Int 2018 9;2018:5610347. Epub 2018 Jan 9.
    Department of Radiological, Oncological and Anatomo-Pathological Sciences, Policlinico Umberto I, Sapienza University of Rome, Viale Regina Elena 324, 00161 Rome, Italy.
    Ectopic cardiac fatty images are not rarely detected incidentally by computed tomography and cardiac magnetic resonance, or by exams focused on the heart as in general thoracic imaging evaluations. A correct interpretation of these findings is essential in order to recognize their normal or pathological meaning, focusing on the eventually associated clinical implications. The development of techniques such as computed tomography and cardiac magnetic resonance allowed a detailed detection and evaluation of adipose tissue within the heart. Read More

    Synchronous bilateral lipoma arborescens of bicipitoradial bursa-a rare entity.
    Skeletal Radiol 2018 Mar 2. Epub 2018 Mar 2.
    Department of Radiology, St. Joseph Hospital, London, ON, N6A 4V2, Canada.
    Lipoma arborescens is a rare non-neoplastic condition that affects the synovial lining of joints and bursae accounting for less than 1% of all lipomatous lesions. Characterized by villous proliferation of the synovium, it is an uncommon cause of intra/periarticular mass presenting as a painless, slowly progressive longstanding swelling, and is sometimes accompanied by intermittent monoarticular effusions. We describe a rare case of bilateral lipoma arborescens in the bicipitoradial bursae in a young male referred for MRI evaluation of spontaneous bilateral elbow swelling. Read More

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