4,874 results match your criteria Lipoid Proteinosis


A rare case of lipoid pneumonia attributed to amiodarone.

Pneumonia (Nathan) 2018 5;10:12. Epub 2018 Dec 5.

Department of Pneumonology, Sotiria Hospital, Athens, Greece.

We report a case of endogenous lipoid pneumonia secondary to long-term use of amiodarone (> 30 years) for atrial fibrillation in a 76-year-old Caucasian woman, presenting with cough and dyspnea. Endogenous Lipoid pneumonia is a rare underdiagnosed condition more prevalent in adults. It is usually asymptomatic and a diagnosis is generally made in patients who have become clinically unstable or when an abnormal lung shadow is found on a chest X-ray. Read More

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December 2018

A Child With a Hoarse Cry and Intracranial Calcification.

Pediatr Neurol 2018 Oct 22;87:78-79. Epub 2018 Aug 22.

Dept. of Pediatric Neurology, Childrens Hospital of Michigan, Wayne State University, Detroit, Michigan.

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October 2018

Conjunctival Colloid Milium.

Cornea 2018 Nov 27. Epub 2018 Nov 27.

Department of Pathology, Vision Research Foundation, Sankara Nethralaya, Chennai, India.

Purpose: To describe a rare case of conjunctival colloid milium.

Methods: Case report.

Results: We report a 45-year-old woman with a history of a slow-growing, painless mass extending from the medial canthal region to the inferior fornix and the inferior bulbar conjunctiva associated with redness. Read More

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November 2018
2 Reads

Pubertal Development and Pregnancy Outcomes in 46,XX Patients with Nonclassic Lipoid Congenital Adrenal Hyperplasia.

J Clin Endocrinol Metab 2018 Nov 23. Epub 2018 Nov 23.

Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan.

Context: Lipoid congenital adrenal hyperplasia (LCAH) is characterized by a disorder of steroidogenesis in both adrenal glands and gonads. 46,XX patients with classic LCAH usually have thelarche and menarche, but show anovulatory menstruations and subsequent premature menopause. Only three patients with classic LCAH have been reported to successfully achieve delivery with the aid of assisted reproductive therapies for conception and progesterone replacement therapy during early pregnancy. Read More

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November 2018
1 Read

Lipoid pneumonia in an orangutan (Pongo abelii) with chronic respiratory problems.

J Med Primatol 2018 Nov 16. Epub 2018 Nov 16.

Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.

An orangutan (Pongo abelii) presented with chronic respiratory problems. Cytological evaluation of the bronchoalveolar lavage fluids revealed macrophages with well-circumscribed intracytoplasmic clear vacuoles and lipid droplets in the background, confirmed by Oil Red O staining. The findings were indicative of lipoid pneumonia. Read More

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November 2018
3 Reads

Does What Goes Around Always Come Around?

Authors:
Howard Trachtman

Clin J Am Soc Nephrol 2018 Dec 15;13(12):1788-1790. Epub 2018 Nov 15.

Division of Nephrology, Department of Pediatrics, New York University Langone Health, New York, New York

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December 2018
1 Read

Long-term follow-up in a Chinese child with congenital lipoid adrenal hyperplasia due to a StAR gene mutation.

BMC Endocr Disord 2018 Nov 6;18(1):78. Epub 2018 Nov 6.

Department of Endocrinology, Shenzhen Children's Hospital, 7019# Yitian Road, Futian District, Shenzhen, 518038, Guangdong Province, China.

Background: Congenital lipoid adrenal hyperplasia (CLAH) is an extremely rare and the most severe form of congenital adrenal hyperplasia. Typical features include disorder of sex development, early-onset adrenal crisis and enlarged adrenal glands with fatty accumulation.

Case Presentation: We report a case of CLAH caused by mutations in the steroidogenic acute regulatory protein (StAR) gene. Read More

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November 2018
5 Reads
1.673 Impact Factor

Genome sequence of 4303.

Gut Pathog 2018 24;10:47. Epub 2018 Oct 24.

1Institute of Bioanalysis, Medical School, University of Pécs, Szigeti út 12, 7624 Pécs, Hungary.

Background: spp. are Gram-negative intracellular pathogenic bacteria belonging to the family and can cause bacterial dysentery, a severe diarrheal disease. The pathophysiological impact of the Gram-negative bacteria is highly related to the composition and structural variability of lipopolysaccharides, the major lipoid components of the outer membrane. Read More

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October 2018
1 Read

Lipoid Proteinosis: A Rare Cause of Hoarseness.

J Voice 2018 Oct 29. Epub 2018 Oct 29.

Department of Otorhinolaryngology-Head and Neck Surgery, Ziekenhuis Oost-Limburg, Genk, Belgium. Electronic address:

Lipoid proteinosis is a rare cause of voice problems. Hoarseness is often the first clinical manifestation of this disorder and can present years before any other symptom. Therefore, it is very important as an otorhinolaryngologist to be familiar with the main characteristics of this disease. Read More

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October 2018

Lipoid Proteinosis.

JAMA Dermatol 2018 Dec;154(12):1479-1480

Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

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December 2018

Emerging therapeutic strategies for minimal change disease and focal and segmental glomerulosclerosis.

Expert Opin Investig Drugs 2018 Nov 30;27(11):839-879. Epub 2018 Oct 30.

a Unit of Nephrology and Dialysis, Department of Internal Medicine , Messina , Italy.

Introduction: Minimal change disease (MCD) and Focal and segmental glomerulosclerosis (FSGS) are two of the major causes of nephrotic syndrome (NS) in children and adults. According to KDIGO (Kidney Disease: Improving Global Outcomes) guidelines, the treatment of adult primary MCD and FSGS should be based on immunosuppressants and antiproteinuric drugs. Recently, Rituximab, a humanized monoclonal antibody (mAb) has emerged as a potential treatment for steroid or calcineurin inhibitor-dependent patients; it has however demonstrated lower efficacy in those with nephrotic syndrome that is resistant to the above indicated drugs. Read More

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November 2018
1 Read
5.530 Impact Factor

[Exogenous lipid pneumonia with hyperpyrexia: a case report].

Authors:
X J Wu M Li Q Y Zhan

Beijing Da Xue Xue Bao Yi Xue Ban 2018 Oct;50(5):921-923

Department of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing 100029, China.

Lipoid pneumonia (LP) is an uncommon form of pneumonia that is characterized by the presence of intra-alveolar lipid and lipid-laden macrophages on microscopy. It categorized as exogenous lipoid pneumonia (ExLP) and endogenous lipoid pneumonia (EnLP). Exogenous lipoid pneumonia caused by inhalation of liposuction substances (animal fat, vegetable oil, or mineral oil), mostly, in adult cases, they were medicines for constipation or rhinopharyngitis. Read More

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October 2018
7 Reads

Comparison of the response of frequently relapsing steroid-dependent minimal change nephrotic syndrome to rituximab therapy between childhood-onset and adult-onset disease.

Medicine (Baltimore) 2018 Oct;97(42):e12704

Department of Medicine, Kidney Center, Tokyo Women's Medical University, Tokyo, Japan.

Rituximab has been approved in Japan for the treatment of intractable nephrotic syndrome, but in cases of childhood-onset disease only; its efficacy and safety in adult-onset disease has yet to be established. This study was undertaken to evaluate the efficacy of rituximab and adverse effects in patients with adult-onset minimal change nephrotic syndrome (MCNS).The study involved 32 childhood-onset cases (mean age at onset: 8. Read More

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October 2018
5 Reads

Increased FDG Uptake and Chronic Lung Changes in a Case of Persistent Lipoid Pneumonia.

Clin Nucl Med 2018 Dec;43(12):e477-e478

From the Department of Diagnostic Radiology, University Hospitals Cleveland Medical Center, Cleveland, OH.

Lipoid pneumonia is uncommon disease caused by presence of macroscopic fat in the lung parenchyma commonly originating from exogenous source secondary to aspiration or inhalation of animal fats or mineral or vegetable oils. Alternatively, it can be due to endogenous fat accumulated in the alveoli in the setting of chronic bronchial obstruction or inflammation. The imaging findings include ground-glass opacities, consolidation, nodules, and masses. Read More

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December 2018
8 Reads

Lipoid pneumonitis in a patient with an accidental ingestion of kerosene successfully treated with bronchoscopic segmental lavage and systemic steroid: Case report.

Medicine (Baltimore) 2018 Oct;97(41):e12786

Department of Internal Medicine, Haeundae Paik Hospital, INJE University College of Medicine, Busan, Korea.

Rationale: Standard treatment of lipoid pneumonitis remains unclear. This study reports a case of kerosene pneumonitis successfully treated with systemic steroid and segmental bronchoalveolar lavage (BAL).

Patient Concerns: A 30-year-old woman referred to our hospital because of worsening of respiratory symptoms and fever despite antibiotic therapy following accidental ingestion of kerosene. Read More

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October 2018
2 Reads

[Clinicopathologic features of lipoprotein glomerulopathy: observation of 6 cases].

Zhonghua Yi Xue Za Zhi 2018 Sep;98(36):2910-2913

Division of Nephrology, China-Japan Friendship Hospital, Beijing 100029, China.

To investigate the clinicopathologic features of lipoprotein glomerulopathy (LPG). A total of 6 cases (5 males and 1 female, with a mean age of 27.5 years and age range of 11-53 years) of lipoprotein glomerulopathy with complete clinicopathologic data were enrolled. Read More

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September 2018
2 Reads

Aberrant Splicing Is the Pathogenicity Mechanism of the p.Glu314Lys Variant in Gene.

Front Endocrinol (Lausanne) 2018 5;9:491. Epub 2018 Sep 5.

Laboratoire de Biochimie et Biologie Moléculaire Grand Est, UM Pathologies Endocriniennes Rénales Musculaires et Mucoviscidose, Groupement Hospitalier Est, Hospices Civils de Lyon, Bron, France.

The cholesterol side chain cleavage enzyme (CYP11A1) catalyzes the conversion of cholesterol to pregnenolone, the first rate-limiting step of steroidogenesis. mutations are associated with primary adrenal insufficiency (PAI) as well as disorders of sex development (DSD) in 46,XY patients. To define the pathogenicity mechanism for the p. Read More

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September 2018
1 Read

Lipoid Proteinosis: Skin Resurfacing with Combination of Fractional CO and Non-ablative Radio Frequency: A Rare Case Report.

J Cutan Aesthet Surg 2018 Apr-Jun;11(2):91-94

Department of Dermatology, CUTIS Academy of Cutaneous Sciences, Bengaluru, Karnataka, India.

Lipoid proteinosis (LP) is a rare autosomal-recessive genodermatosis, characterized by the deposition of amorphous hyaline-like material in different parts of the body, especially the skin and mucous membranes. Disfiguring lesions predominantly affect the facial appearance. No curative therapy and treatment options limited to symptomatic approaches are available. Read More

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September 2018
1 Read

Exogenous lipoid pneumonia associated with oil pulling: Report of two cases.

Monaldi Arch Chest Dis 2018 Sep 7;88(3):922. Epub 2018 Sep 7.

Grantham Hospital, TB and Chest Unit.

Two ladies with history of carcinoma of tongue presenting with un-resolving pneumonia were ultimately diagnosed to have lipoid pneumonia, and both were subsequently found to be associated with the practice of oil pulling which is a popular complementary therapy. Apart from cessation of oil pulling, they were treated with repeated therapeutic lobar broncho-alveolar lavage. despite the potential benefits of oil pulling on oral health, people especially those at risk of aspiration, should be properly informed of this potential risk when considering this form of complementary therapy. Read More

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September 2018
1 Read

Adult exogenous lipoid pneumonia: A rare and underrecognized entity in cytology - A case series.

Cytojournal 2018 13;15:17. Epub 2018 Jul 13.

Address: Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.

Background: Exogenous lipoid pneumonia (ELP) is a rare benign entity without specific clinical or imaging presentation. Although cytological studies - either bronchoalveolar lavage (BAL) or fine-needle aspiration (FNA) - may be pursued in patients with ELP, a definitive diagnosis is frequently rendered only on histology. The aim of this study is to highlight the cytological features of ELP. Read More

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July 2018
1 Read

The management of laryngeal lipoid proteinosis.

J Laryngol Otol 2018 Oct 13;132(10):936-939. Epub 2018 Aug 13.

National Centre for Airway Reconstruction,Charing Cross Hospital,Imperial College Healthcare NHS Trust,London,UK.

Background: Lipoid proteinosis is a rare autosomal recessive disorder caused by mutations in the extracellular matrix protein 1 gene. It is characterised by deposition of hyaline material in the skin and mucous membranes. This paper describes the management of two cases with laryngopharyngeal disease. Read More

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October 2018
1 Read

Exogenous lipoid pneumonia: an important cause of interstitial lung disease in infants.

Respirol Case Rep 2018 Oct 7;6(7):e00356. Epub 2018 Aug 7.

Division of Paediatric Pulmonology, Department of Paediatrics and Child Health and Medical Research Council Unit on Child and Adolescent Health University of Cape Town Cape Town South Africa.

Exogenous lipoid pneumonia (ELP), an important cause of interstitial lung disease, often goes unrecognized. We conducted a retrospective study of children with histologically confirmed ELP at Red Cross Children's Hospital, South Africa. Twelve children of Zimbabwean heritage aged 2. Read More

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October 2018

In-vitro and in-vivo antileishmanial activity of inexpensive Amphotericin B formulations: Heated Amphotericin B and Amphotericin B-loaded microemulsion.

Exp Parasitol 2018 Sep 1;192:85-92. Epub 2018 Aug 1.

Université Paris-Sud, Faculté de Pharmacie, UMR 8076 CNRS BioCIS, Châtenay-Malabry, France. Electronic address:

Amphotericin B (AmB) is effective against visceral leishmaniasis (VL), but the renal toxicity of the conventional form, mixed micelles with deoxycholate (M-AmB), is often dose-limiting, while the less toxic lipid-based formulations such as AmBisome are very expensive. Two different strategies to improve the therapeutic index of AmB with inexpensive ingredients were evaluated on this work: (i) the heat treatment of the commercial formulation (H-AmB) and (ii) the preparation of an AmB-loaded microemulsion (ME-AmB). M-AmB was heated to 70 °C for 20 min. Read More

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September 2018
84 Reads

Impact of Ocular Compatible Lipoids and Castor Oil in Fabrication of Brimonidine Tartrate Nanoemulsions by 3 Full Factorial Design.

Recent Pat Inflamm Allergy Drug Discov 2018 ;12(2):169-183

Rayat-Bahra Institute of Pharmacy, Rayat-Bahra University, Punjab, India.

Background: Brimonidine Tartrate (BRT) is used in the treatment of glaucoma. Brimonidine tartrate nanoemulsion was fabricated in this research work to enhance the permeability through barriers and faster onset of action and therapeutic effect.

Objective: To fabricate an ocular compatible nanoemulsion of brimonidine tartrate by using surfactant and co-surfactants. Read More

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December 2018

The effect of nanoemulsified methionine and cysteine on the in vitro expression of casein in bovine mammary epithelial cells.

Asian-Australas J Anim Sci 2018 Jul 26. Epub 2018 Jul 26.

National Institute of Animal Science, Rural Development of Administration, Cheonan, Korea.

Dairy cattle nutrient requirement systems acknowledge amino acid (AA) requirements in aggregate as metabolizable protein (MP) and assume fixed efficiencies of MP used for milk protein. Regulation of mammary protein synthesis may be is associated with AA input and milk protein output. The aim of this study is to evaluate the effect of nanoemulsified methionine and cysteine on the in-vitro expression of milk protein (casein) in bovine mammary epithelial cells MAC-T cells). Read More

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July 2018
1 Read

Lipoid proteinosis: Unfamiliar skin findings delay diagnosis.

JAAD Case Rep 2018 Jul 28;4(6):609-611. Epub 2018 Jun 28.

Department of Dermatology, Mayo Clinic, Rochester, Minnesota.

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Exogenous Lipoid Pneumonia due to Chronic Inhalation of Oily Product Used as a Lubricant of Tracheotomy Cannula.

Eurasian J Med 2018 Jun 1;50(2):125-127. Epub 2018 Jun 1.

Unit of General Surgery 2nd and Thoracic Surgery, IRCCS " Casa Sollievo della Sofferenza" Hospital, San Giovanni Rotondo, Foggia, Italy.

Exogenous lipoid pneumonia (ELP) is caused by the inhalation of vaporized oily products. Long-term exposure can result in chronic disease, whereas acute form usually results from massive aspiration of fatty substances. It has an incidence of 1. Read More

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Recurrence of nephrotic syndrome following kidney transplantation is associated with initial native kidney biopsy findings.

Pediatr Nephrol 2018 Oct 7;33(10):1773-1780. Epub 2018 Jul 7.

Department of Pediatrics, Divisions of Nephrology and Critical Care, Duke University Medical Center, Durham, NC, 27710, USA.

Background And Objectives: Steroid-resistant nephrotic syndrome (SRNS) due to focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD) is a leading cause of end-stage kidney disease in children. Recurrence of primary disease following transplantation is a major cause of allograft loss. The clinical determinants of disease recurrence are not completely known. Read More

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October 2018
1 Read

Respiratory failure caused by lipoid pneumonia from vaping e-cigarettes.

BMJ Case Rep 2018 Jul 6;2018. Epub 2018 Jul 6.

Respiratory Medicine, Birmingham Heartlands Hospital, Birmingham, UK.

A young female vaper presented with insidious onset cough, progressive dyspnoea on exertion, fever, night sweats and was in respiratory failure when admitted to hospital. Clinical examination was unremarkable. Haematological tests revealed only thrombocytopenia, which was long standing, and her biochemical and inflammatory markers were normal. Read More

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July 2018
8 Reads

Floral nectary and osmophore of Epipactis helleborine (L.) Crantz (Orchidaceae).

Protoplasma 2018 Nov 9;255(6):1811-1825. Epub 2018 Jun 9.

Faculty of Materials Science and Engineering, Warsaw University of Technology, Wołoska 141, 02-507, Warsaw, Poland.

The analysis of flowers collected at different stages of anthesis provides strong evidence to conclude that the shell-shaped hypochile and the knobs of epichile form a nectary. The scent comes from the aromatic constituents of nectar and the epichile tissue and the apices of all tepals (osmophores). The comparison between pollinated and unpollinated flowers revealed that the anthesis of unpollinated flowers lasted up to the 16th day. Read More

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November 2018

An unusual cause of respiratory distress.

J Postgrad Med 2018 Jun 21. Epub 2018 Jun 21.

Department of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

Exogenous lipoid pneumonia is a rare alveolar-filling disorder characterized by foreign body reaction to inhaled/aspirated hydrocarbon that may be vegetable oil, animal fat, or mineral oil. It is vanishingly rare and often missed except in the classical clinical settings of acute aspiration of petroleum products. We present a toddler with iatrogenic exogenous lipoid pneumonia and highlight clinical and radiological clues that can prompt early recognition of this entity. Read More

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June 2018
8 Reads

Percutaneous Sclerotherapy of Superficial Vascular Malformation Leading to Bleomycin Induced Lung Injury and Lipoid Pneumonia.

Indian J Pediatr 2018 Jun 22. Epub 2018 Jun 22.

Department of Pediatrics, All India Institute of Medical Sciences, Jodhpur, Rajasthan, 342005, India.

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June 2018
5 Reads

Hydroxypropyl-ß-cyclodextrin as a membrane protectant during freeze-drying of hydrogenated and non-hydrogenated liposomes and molecule-in-cyclodextrin-in- liposomes: Application to trans-anethole.

Food Chem 2018 Nov 31;267:67-74. Epub 2017 Oct 31.

Laboratoire d'Automatique et de Génie des Procédés, Université Claude Bernard Lyon 1, UMR 5007, CNRS, CPE, 43 bd du 11 Novembre, 691622 Villeurbanne Cedex, France. Electronic address:

The effect of hydrogenation of phospholipids on the characteristics of freeze-dried liposomes was investigated using hydroxypropyl-ß-cyclodextrin (HP-ß-CD) as membrane protectant. The ethanol-injection method was applied to prepare liposomes using hydrogenated (Phospholopion-90H and 80H) and non-hydrogenated phospholipids (Lipoid-S100) in combination with cholesterol. Various liposomal formulations were tested: conventional liposomes (CL) and HP-ß-CD-loaded liposomes (CDL). Read More

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November 2018
4 Reads

Effect of Complexes and Microemulsions on the Permeability of Drugs: Determination Using a New Biomimetic Artificial Membrane.

AAPS PharmSciTech 2018 Jun 19. Epub 2018 Jun 19.

Unidad de Investigación y Desarrollo en Ciencia y Tecnología Farmacéutica (UNITEFA-CONICET), Departamento de Farmacia, Facultad de Ciencias Químicas-Universidad Nacional de Córdoba, Ciudad Universitaria, X5000HUA, Córdoba, Argentina.

The aim of this work was to predict the permeability of two model drugs, sulfamerazine (SMR) and indomethacin (INM), and to determine the effect on their apparent permeabilities by complexation with cyclodextrins and/or meglumine or incorporation in microemulsions. Permeation experiments were performed using two-chamber diffusion cells with a new composition of bio-mimetic membrane composed of 80% of Lipoid® S100 and 20% of cholesterol in n-octanol 10% w/w solution, at 37 ± 0.5°C and 14,000 rpm. Read More

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June 2018
2 Reads

The Spectrum of Biopsy-Proven Glomerular Diseases among Children in China: A National, Cross-Sectional Survey.

Clin J Am Soc Nephrol 2018 Jul 18;13(7):1047-1054. Epub 2018 Jun 18.

The National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Renal Division, Nanfang Hospital and

Background And Objectives: High-quality epidemiologic data on the spectrum of biopsy-proven glomerular diseases among children are limited. This study aimed to determine the profile of and temporal change in biopsy-proven pediatric glomerular diseases in China.

Design, Setting, Participants, & Measurements: We previously conducted a nationwide kidney biopsy survey including 71,151 patients over an 11-year period from January 2004 to December 2014. Read More

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July 2018
31 Reads

[Chronic lymphoid leukemia and renal complication: Report on 10 cases from Marseille over 16 years].

Rev Med Interne 2018 Aug 8;39(8):612-617. Epub 2018 Jun 8.

Médecine interne, hôpital de la Timone (AP-HM), Aix-Marseille université, 264, rue Saint-Pierre, 13385 Marseille cedex 05, France. Electronic address:

Introduction: Chronic lymphoid leukemia (CLL) is a hematological malignant disease, associated with a clonal B cell proliferation. The incidence is 4400 new cases per year in France. The prevalence increases with age with a median age at diagnostic of 65 years. Read More

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August 2018
9 Reads

[Electronic Cigarette: not all that glitters is gold]

Rev Fac Cien Med Univ Nac Cordoba 2017 09 8;74(3):271-276. Epub 2017 Sep 8.

Clinica Universitaria Reina Fabiola.

Introduction: Smoking is the leading preventable cause of death in the world. Electronic Cigarette (EC) is a device that simulates a conventional cigarette and allows inhale nicotine and other substances in a vaporized form, without combustion of snuff. Because it´s marketing and availability, it´s use comes with a steady increase. Read More

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September 2017
2 Reads

Minimal change disease related to rifampicin presenting with acute renal failure during treatment for latent tuberculosis infection: A case report.

Medicine (Baltimore) 2018 Jun;97(22):e10556

Department of Internal Medicine, Yeungnam University Medical Center.

Rationale: The standard drugs used to treat tuberculosis are rifampicin and isoniazid. These agents are usually safe and inexpensive for short-term use in treatment of latent tuberculosis infection, but sometimes cause adverse renal effects, including minimal change disease (MCD).

Patient Concerns: Here, we report a 51-year-old woman with latent tuberculosis infection who developed nephrotic syndrome during treatment with rifampicin and isoniazid for 25 days. Read More

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June 2018
10 Reads

Comparison of exogenous and endogenous lipoid pneumonia: the relevance to bronchial anthracofibrosis.

J Thorac Dis 2018 Apr;10(4):2461-2466

Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.

Lipoid pneumonia, caused by the accumulation of lipids in the alveoli, is classified into two forms (exogenous endogenous) according to the source of the lipid exposure. There are no data directly comparing patients with exogenous and endogenous lipoid pneumonia. All patients who were diagnosed with lipoid pneumonia between January 2008 and December 2016 at Kyungpook National University Hospital, a tertiary referral hospital in South Korea, were retrospectively reviewed. Read More

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April 2018
4 Reads

Histopathological Spectrum and Short-Term Outcome of Treatment with Cyclophosphamide in Relapsing Steroid-Sensitive Nephrotic Syndrome.

J Coll Physicians Surg Pak 2018 Jun;28(6):436-439

Department of Pediatric Nephrology, Sindh Institute of Urology and Transplantation, Karachi.

Objective: To determine the short-term outcome of cyclophosphamide (CPO) course in children with relapsing steroid sensitive nephrotic syndrome (SSNS) with different histopathological lesions.

Study Design: Descriptive, observational study.

Place And Duration Of Study: Pediatric Nephrology Department, Sindh Institute of Urology and Transplantation, Karachi, from January 2012 to December 2014. Read More

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June 2018
2 Reads

Lipoid proteinosis: a first report of mutation Val10Gly in the signal peptide of the ECM1 gene.

Postepy Dermatol Alergol 2018 Apr 24;35(2):208-211. Epub 2018 Apr 24.

Department of Dermatology, Stefan Zeromski Krakow Municipal Hospital, Krakow, Poland.

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Pancreatic Lipomatous Hamartoma: A Hitherto Unrecognized Variant.

Am J Surg Pathol 2018 Jul;42(7):891-897

Departments of Pathology.

Pancreatic masses consisting of lipomatous components clinically include lipoma, liposarcoma, lipomatous pseudohypertrophy of the pancreas, fat-containing neoplasms such as perivascular epithelioid cell tumor, and malignant neoplasm with lipoid degeneration. We present pancreatic lipomatous hamartoma, which has not been reported hitherto. A solid pancreatic mass was detected from a computed tomographic scan check-up in each of 3 cases of Japanese men. Read More

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July 2018
1 Read

Development of transethosomes formulation for dermal fisetin delivery: Box-Behnken design, optimization, in vitro skin penetration, vesicles-skin interaction and dermatokinetic studies.

Artif Cells Nanomed Biotechnol 2018 May 7:1-11. Epub 2018 May 7.

a Department of Pharmaceutics, School of Pharmaceutical Education and Research , Jamia Hamdard (Deemed University) , New Delhi , India.

The present study was conducted for the optimization of transethosomes formulation for dermal fisetin delivery. The optimization of the formulation was carried out using "Box-Behnken design". The independent variables were Lipoid S 100, ethanol and sodium cholate. Read More

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May 2018
18 Reads

Moniliform blepharosis in lipoid proteinosis with a homozygous ECM1 gene mutation.

Ophthalmic Genet 2018 Aug 2;39(4):550-552. Epub 2018 May 2.

d Department of Psychiatry , Ege University , Izmir , Turkey.

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August 2018
2 Reads

Pathogenetic mechanism of lipoid proteinosis caused by mutation of the extracellular matrix protein 1 gene.

Mol Med Rep 2018 Jun 24;17(6):8087-8090. Epub 2018 Apr 24.

Department of Laboratory and Oncology, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, P.R. China.

Lipoid proteinosis (LP) is a rare form of dermatosis with autosomal recessive inheritance. The present study hypothesized that an extracellular matrix protein 1 (ECM1) gene mutation forms the pathological basis of LP. The association between ECM1 mutation and LP; however, requires further investigation and was thus investigated in the present study. Read More

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June 2018
1 Read

Esophageal Aperistalsis in a Patient with Lipoid Proteinosis.

Middle East J Dig Dis 2018 Jan 14;10(1):55-58. Epub 2018 Jan 14.

Digestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

Lipoid proteinosis is a rare disorder with autosomal recessive inheritance, characterized by progressive deposition of hyaline material in the skin, mucous membrane, and different organs of the body, resulting in a multitude of clinical manifestations. A 34-year-old woman presented with hoarseness, dysphagia, eyelid beeding, and acneiform scars on the facial skin and extremities. The patient was diagnosed clinically as having lipoid proteinosis, which was confirmed by laryngeal biopsy. Read More

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January 2018
15 Reads

[Exogenous lipoid pneumonia. Report of three cases].

Rev Med Chil 2017 Nov;145(11):1495-1499

Servicio Medicina, Instituto Nacional del Tórax, Santiago, Chile.

Lipoid pneumonia is an unusual cause of aspiration pneumonia with diverse radiologic manifestations. One of these are pulmonary nodules in which the main differential diagnosis is pulmonary carcinoma. We report an 85 years old male, an 85 years old female and a 34 years old male in whom percutaneous biopsies of suspicious nodules were compatible with lipoid pneumonia. Read More

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November 2017
13 Reads

Regional variation in percutaneous absorption in the tree frog Litoria caerulea.

Environ Toxicol Pharmacol 2018 Jun 28;60:5-11. Epub 2018 Mar 28.

Pharmacy, College of Medicine and Dentistry, James Cook University, Townsville, 4811, Australia.

Frog skin structure and physiology differs between skin regions, however little is known about how these differences affect transdermal absorption of chemicals. Further, no information is available regarding how the relative lipophilicity of a chemical influences its transdermal pharmacokinetics in frog skin. This study investigated the in vitro percutaneous absorption of three model chemicals - benzoic acid, caffeine, and ibuprofen - through dorsal and ventral skin of the tree frog Litoria caerulea. Read More

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June 2018
3 Reads

Löfgren syndrome as secondary autoimmune disease in a patient with B-cell depletion following rituximab treatment.

Clin Exp Rheumatol 2018 May-Jun;36(3):515-516. Epub 2018 Mar 21.

Central Institute for Medical and Chemical Laboratory Diagnostics, Medical University Innsbruck, Austria.

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July 2018
12 Reads

A rare cause of primary adrenal insufficiency due to a homozygous Arg188Cys mutation in the gene.

Endocrinol Diabetes Metab Case Rep 2018 21;2018. Epub 2018 Mar 21.

Pediatric Endocrinology, Diabetology and Metabolism, Bern University Children's Hospital and Department of BioMedical Research, University of Bern, Bern, Switzerland.

Steroidogenic acute regulatory protein () is a key protein for the intracellular transport of cholesterol to the mitochondrium in endocrine organs (e.g. adrenal gland, ovaries, testes) and essential for the synthesis of all steroid hormones. Read More

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March 2018
4 Reads