1,486 results match your criteria Lip Reduction


Lengthening temporalis myoplasty and reduction of the swallowing oral phase dysfunction in facial palsy patients.

J Plast Reconstr Aesthet Surg 2019 Mar 1. Epub 2019 Mar 1.

Department of Maxillofacial and Plastic Facial Surgery, Trousseau Hospital, Tours 37000, France; University of François Rabelais, school of medicine, Tours 37000, France; Department of Pediatric Maxillofacial Surgery, Clocheville Hospital, Tours, 37000 France.

Introduction: Facial palsy can cause dysfunction in the oral phase of swallowing. Lengthening temporalis myoplasty is a widely used technique for correction of facial asymmetry in facial palsy. The aim of this study was to determine whether lengthening temporalis myoplasty could reduce the dysfunction in the oral phase of swallowing in patients with facial palsy. Read More

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http://dx.doi.org/10.1016/j.bjps.2019.02.027DOI Listing

Non-Vitamin K Antagonist Oral Anticoagulants Versus Warfarin in Atrial Fibrillation Patients With Intracerebral Hemorrhage.

Stroke 2019 Mar 14:STROKEAHA118023797. Epub 2019 Mar 14.

From the Department of Cardiology, Aalborg University Hospital, Denmark (P.B.N., M.S., J.N.K., T.B.L.).

Background and Purpose- Recurrent bleeding associated with oral anticoagulants (OACs) causes a dilemma in patients with atrial fibrillation (AF) sustaining an intracerebral hemorrhage. Treatment recommendations guiding clinical practice on optimal OAC agent selection in this population are lacking. This study aimed to investigate the comparative effectiveness and safety of non-vitamin K antagonist OAC (NOAC) versus warfarin in patients with AF sustaining an intracerebral hemorrhage. Read More

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http://dx.doi.org/10.1161/STROKEAHA.118.023797DOI Listing
March 2019
1 Read

Direct Oral Anticoagulants in Patients With Nonvalvular Atrial Fibrillation and Low Body Weight.

J Am Coll Cardiol 2019 Mar;73(8):919-931

Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Chest & Heart Hospital, Liverpool, United Kingdom; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.

Background: It is unclear whether the overall effectiveness and safety of direct oral anticoagulants (DOACs) are consistent in patients with nonvalvular atrial fibrillation (AF) and extremely low body weight (<50 kg).

Objectives: This study compared DOACs with warfarin in AF patients with low body weight.

Methods: Using data from the Korean National Health Insurance Service database from January 2014 to December 2016, AF patients with body weight ≤60 kg and who were treated with oral anticoagulants (n = 14,013 taking DOACs and n = 7,576 taking warfarin) were included and examined for ischemic stroke, intracranial hemorrhage (ICH), gastrointestinal bleeding, major bleeding, all-cause death, and composite outcome. Read More

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http://dx.doi.org/10.1016/j.jacc.2018.11.051DOI Listing
March 2019
1 Read

Pulse Pressure and Prognosis in Patients with Heart Failure with Reduced Ejection Fraction.

Eur J Clin Invest 2019 Feb 23:e13092. Epub 2019 Feb 23.

Department of Cardiology, Lehigh Valley Health Network, Allentown, PA, USA.

Background: A high pulse pressure (PP) is associated with adverse cardiovascular (CV) outcomes; however this relationship may be reversed in patients with heart failure with reduced ejection fraction (HFREF).

Methods: Patients from the WARCEF trial with left ventricular ejection fraction < 35% were included. PP was divided into tertiles: <42, 42-54 and >54 mm Hg. Read More

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http://doi.wiley.com/10.1111/eci.13092
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http://dx.doi.org/10.1111/eci.13092DOI Listing
February 2019
3 Reads

Genetic deletion of genes in the cerebellar rhombic lip lineage can stimulate compensation through adaptive reprogramming of ventricular zone-derived progenitors.

Neural Dev 2019 Feb 14;14(1). Epub 2019 Feb 14.

Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, Box 511, New York, NY, 10065, USA.

Background: The cerebellum is a foliated posterior brain structure involved in coordination of motor movements and cognition. The cerebellum undergoes rapid growth postnataly due to Sonic Hedgehog (SHH) signaling-dependent proliferation of ATOH1+ granule cell precursors (GCPs) in the external granule cell layer (EGL), a key step for generating cerebellar foliation and the correct number of granule cells. Due to its late development, the cerebellum is particularly vulnerable to injury from preterm birth and stress around birth. Read More

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http://dx.doi.org/10.1186/s13064-019-0128-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375182PMC
February 2019
1 Read

Unstable Dorsal Fracture-Dislocations of the Proximal Interphalangeal Joint: Volar Plate Fixation with or without Bone Graft.

J Hand Surg Asian Pac Vol 2019 Mar;24(1):50-54

1 Birmingham Hand Centre, Queen Elizabeth Hospital, Birmingham, UK.

Background: To evaluate the treatment of severe dorsal fracture dislocation (DFD) injuries of the proximal interphalangeal joint (PIPJ) by open reduction, bone grafting and fixation with mini-hook plates.

Methods: Fourteen patients with extensive dorsal fracture dislocation of the PIPJ were operatively treated to reconstruct the fractured middle phalanx volar lip using a fabricated hook plate in conjunction with elevation and bone grafting of depressed articular fragments where present.

Results: Restoration of PIPJ articular anatomy and congruence by hook plate fixation permitted full-range mobilization of the joint during fracture healing, with an average arc of motion of 81° and an average loss of extension of 12. Read More

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http://dx.doi.org/10.1142/S2424835519500097DOI Listing
March 2019
1 Read

Comparative evaluation of a single 2.0-mm AO locking reconstruction plate with conventional miniplate osteosynthesis for treatment of linear non-comminuted fractures of symphysis and parasymphsis region of the mandible.

J Stomatol Oral Maxillofac Surg 2019 Feb 26;120(1):11-15. Epub 2018 Oct 26.

Department of oral and maxillofacial surgery, government dental college and hospital, Ahmedabad, India.

The objective of the study was to evaluate and compare the relative efficacy of treating linear non-comminuted mandibular fracture of symphysis and parasymphysis region using single 2.0-mm AO locking reconstruction plate or using two conventional miniplates. In this study, 80 patients of symphysis or parasymphysis fracture were divided randomly in two equal groups and treated with open reduction and internal fixation using two 2. Read More

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http://dx.doi.org/10.1016/j.jormas.2018.10.002DOI Listing
February 2019
1 Read

Soft Tissue Changes Following Combined Anterior Segmental Bimaxillary Orthognathic Procedures.

J Maxillofac Oral Surg 2019 Mar 16;18(1):93-99. Epub 2018 Mar 16.

3Clinical Psychology, Delhi University, New Delhi, India.

Aims & Objectives: To analyze the soft tissue response in patients treated by combined anterior segmental bimaxillary procedures.

Methods: A  Prospective, observational and analytical study was carried out for a period of 2 years involving 37 patients with predefined inclusion and exclusion criteria; lateral cephalograms were taken by the same operator on the standardized unit immediately before and 6 months after surgery; hard and soft tissue landmarks were measured in millimeters to both horizontal and vertical reference lines; any differences in distances were recorded as a surgical change; appropriate statistical test was carried; level of significance was  < 0.05. Read More

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http://dx.doi.org/10.1007/s12663-018-1099-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328814PMC
March 2019
1 Read

Association of International Normalized Ratio Stability and Bleeding Outcomes Among Atrial Fibrillation Patients Undergoing Percutaneous Coronary Intervention.

Circ Cardiovasc Interv 2019 Feb;12(2):e007124

Division of Cardiovascular Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (M.K., M.K.Y., T.N., C.M.G.).

Background: Among atrial fibrillation patients undergoing percutaneous coronary intervention enrolled in PIONEER AF-PCI (An Open-Label, Randomized, Controlled, Multicenter Study Exploring Two Treatment Strategies of Rivaroxaban and a Dose-Adjusted Oral Vitamin K Antagonist Treatment Strategy in Subjects With Atrial Fibrillation Who Undergo Percutaneous Coronary Intervention), it is unclear if the observed reduction in bleeding events with rivaroxaban regimens is consistent across a range of the international normalized ratio (INR) among subjects administrated Vitamin K antagonist (VKA)-triple therapy. This analysis compares the occurrence of clinically significant bleeding between rivaroxaban and VKA strategies, according to INR stability of subjects administrated VKA.

Methods And Results: A total of 2124 atrial fibrillation patients undergoing percutaneous coronary intervention were randomized to 3 groups: rivaroxaban 15 mg od plus a P2Y inhibitor (group 1, n=709); rivaroxaban 2. Read More

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.118.007124DOI Listing
February 2019
2 Reads

Dentoalveolar Arch Dimensions in UCLP Boys After Neonatal Cheiloplasty or After Lip Surgery at the Age of 3 or 6 Months.

Cleft Palate Craniofac J 2019 Jan 29:1055665618824835. Epub 2019 Jan 29.

1 Department of Stomatology, Kralovske Vinohrady University Hospital and Third Faculty of Medicine, Charles University, Prague, Czech Republic.

Objective:: To compare the influence of 3 different time protocols of cleft lip and palate operations on the growth of the dentoalveolar arch in patients with unilateral cleft lip and palate (UCLP).

Materials And Methods:: We evaluated 64 plaster casts of 8-year-old boys with UCLP operated on according to 3 different time protocols: lip repair at the age of 6 months and palate repair at 4 years, lip repair at 3 months and palate repair at 9 months, and neonatal lip repair and palate repair at 9 months. The control group contained 13 plaster casts of 8-year-old boys. Read More

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http://dx.doi.org/10.1177/1055665618824835DOI Listing
January 2019

Study on Tooth Movement After the Alveolar Bone Grafting in Patients With Unilateral Cleft Lip and Palate.

J Craniofac Surg 2019 Jan 23. Epub 2019 Jan 23.

Department of Orthodontics.

Objectives: The aim of the study was to explore the effectiveness of the cleft-adjacent teeth moved into the grafted alveolar bone in unilateral cleft lip and palate (UCLP) patients, and to evaluate the alveolar bone support of the teeth.

Methods: Twenty unilateral cleft lip and palate patients were recruited in this study. The average age was 12 years and 8 months. Read More

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http://dx.doi.org/10.1097/SCS.0000000000005111DOI Listing
January 2019

A cleft lip and palate gene, Irf6, is involved in osteoblast differentiation of craniofacial bone.

Dev Dyn 2019 Mar 7;248(3):221-232. Epub 2019 Feb 7.

Center for Craniofacial Research, Department of Diagnostic and Biomedical Sciences, School of Dentistry, University of Texas Health Science Center at Houston, Houston, Texas.

Background: Interferon regulatory factor 6 (IRF6) plays a critical role in embryonic tissue development, including differentiation of epithelial cells. Besides orofacial clefting due to haploinsufficiency of IRF6, recent human genetic studies indicated that mutations in IRF6 are linked to small mandible and digit abnormalities. The function of IRF6 has been well studied in oral epithelium; however, its role in craniofacial skeletal formation remains unknown. Read More

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http://dx.doi.org/10.1002/dvdy.13DOI Listing

Interdisciplinary planning as a landmark for treatment: Case report with a 2-years follow-up.

Dental Press J Orthod 2018 Nov-Dec;23(6):41.e1-41.e12

Private practice (Alessandria/AL, Italy).

Case Report: young adult woman with esthetic complaints regarding her smile and frontal teeth aspect. At first glance, the problem seemed to be only the shape of the lateral upper incisors and a small diastema between the central incisors. The diagnosis shared between the orthodontist and the prosthetist led us to consider some other important aspects, such as the deep bite, the teeth inclination and the lips support. Read More

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http://dx.doi.org/10.1590/2177-6709.23.6.41.e1-12.onlDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340192PMC
January 2017

Evaluation of a Medicaid Lock-in Program: Increased Use of Opioid Use Disorder Treatment but No Impact on Opioid Overdose Risk.

Med Care 2019 Mar;57(3):213-217

Duke Clinical Research Institute, Durham, NC.

Background: "Lock-in" programs (LIPs) identify beneficiaries demonstrating potential overutilization of opioids, and other controlled substances, and restrict their access to these medications. LIPs are expanding to address the opioid crisis and could be an effective tool for connecting people to opioid use disorder treatment. We examined the immediate and sustained effects of a Medicaid LIP on overdose risk and use of medication-assisted treatment (MAT) for opioid use disorder. Read More

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http://dx.doi.org/10.1097/MLR.0000000000001058DOI Listing
March 2019
10 Reads

[Imaging for treatment planning in lipo-and lymphedema].

Handchir Mikrochir Plast Chir 2018 Dec 8;50(6):386-392. Epub 2019 Jan 8.

Universitätsklinikum Erlangen Plastisch- und Handchirurgische.

Lipoedema is a progressive disease, which predominantly affects women. It is characterised by circumferential growth, with increase in fat tissue of the extremities, and can lead to oedema. In contrast, the lymphoedema is defined by a specific lymphatic drainage disorder and can lead to fibrosis of the surrounding connective tissue. Read More

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http://dx.doi.org/10.1055/a-0739-7911DOI Listing
December 2018
8 Reads

Effectiveness and Safety of Oral Anticoagulants Among Nonvalvular Atrial Fibrillation Patients.

Stroke 2018 Dec;49(12):2933-2944

Department of Hospital Medicine, Ochsner Clinic Foundation, New Orleans, LA; and Ochsner Clinical School, University of Queensland School of Medicine, New Orleans, LA (S.D.).

Background and Purpose- This ARISTOPHANES study (Anticoagulants for Reduction in Stroke: Observational Pooled Analysis on Health Outcomes and Experience of Patients) used multiple data sources to compare stroke/systemic embolism (SE) and major bleeding (MB) among a large number of nonvalvular atrial fibrillation patients on non-vitamin K antagonist oral anticoagulants (NOACs) or warfarin. Methods- A retrospective observational study of nonvalvular atrial fibrillation patients initiating apixaban, dabigatran, rivaroxaban, or warfarin from January 1, 2013, to September 30, 2015, was conducted pooling Centers for Medicare and Medicaid Services Medicare data and 4 US commercial claims databases. After 1:1 NOAC-warfarin and NOAC-NOAC propensity score matching in each database, the resulting patient records were pooled. Read More

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.118.020232
Publisher Site
http://dx.doi.org/10.1161/STROKEAHA.118.020232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257512PMC
December 2018
6 Reads

Increase of Redox Potential during the Evolution of Enzymes Degrading Recalcitrant Lignin.

Chemistry 2019 Feb 25;25(11):2708-2712. Epub 2019 Jan 25.

Centro de Investigaciones Biológicas, CSIC, Ramiro de Maeztu 9, E-28040, Madrid, Spain.

To investigate how ligninolytic peroxidases acquired the uniquely high redox potential they show today, their ancestors were resurrected and characterized. Unfortunately, the transient Compounds I (CI) and II (CII) from peroxide activation of the enzyme resting state (RS) are unstable. Therefore, the reduction potentials (E°') of the three redox couples (CI/RS, CI/CII and CII/RS) were estimated (for the first time in a ligninolytic peroxidase) from equilibrium concentrations analyzed by stopped-flow UV/Vis spectroscopy. Read More

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http://doi.wiley.com/10.1002/chem.201805679
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http://dx.doi.org/10.1002/chem.201805679DOI Listing
February 2019
5 Reads

"Pro-bird" floral traits discourage bumblebee visits to Penstemon gentianoides (Plantaginaceae), a mixed-pollinated herb.

Naturwissenschaften 2018 Dec 17;106(1-2). Epub 2018 Dec 17.

Departamento de Biología Evolutiva, Instituto de Ecología, AC (INECOL), Carretera Antigua a Coatepec No. 351, El Haya, Xalapa, 91070, Veracruz, Mexico.

The pollination syndrome concept implies that flowers evolved with particular sets of characteristics, such as colors, shapes, orientations, and rewards, as a means of attracting pollinators. However, these traits may have also evolved to deter unwanted visitors. The North American genus Penstemon exhibits a great floral diversity that is mainly associated with bumblebee and hummingbird pollination. Read More

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http://dx.doi.org/10.1007/s00114-018-1595-4DOI Listing
December 2018

Efficacy of Platelet-Rich Fibrin Combined with Autogenous Bone Graft in the Quality and Quantity of Maxillary Alveolar Cleft Reconstruction.

Iran J Otorhinolaryngol 2018 Nov;30(101):329-334

Department of Oral and Maxillofacial Surgery, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.

Introduction: The aim of this study was to evaluate the effect of platelet-rich fibrin (PRF) on the quality and quantity of bone formation in unilateral maxillary alveolar cleft reconstruction using cone beam computed tomography.

Materials And Methods: This study was conducted on 10 non-syndromic patients with unilateral cleft lip and palate within the age group of 9-12 years. The study population was randomly assigned into two groups of PRF and control, each of which entailed 5 cases. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291813PMC
November 2018
1 Read

Surgical Correction of Double Upper Lip Deformities Without Mucosal Excision: A Transvestibular Approach.

Int J Periodontics Restorative Dent 2019 Jan/Feb;39(1):49-54

Double lip is a rare deformity that mainly affects the upper lip. The typical clinical image involves bilateral mucosal pads separated by a central groove that appear superimposed over the maxillary incisors. The deformity is rather noticeable and esthetically disturbing. Read More

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http://dx.doi.org/10.11607/prd.3450DOI Listing
December 2018
1 Read

Evaluation of accuracy and sensory outcomes of mandibular reconstruction using computer-assisted surgical simulation.

J Craniomaxillofac Surg 2019 Jan 11;47(1):6-14. Epub 2018 Oct 11.

Department of Oral and Maxillofacial Surgery, Ninth People's Hospital, Collage of Stomatology, Shanghai JiaoTong University School of Medicine, Shanghai, China. Electronic address:

Purpose: To introduce a modified protocol for mandibular reconstruction and evaluate the protocol using a standardized assessment method.

Method: This retrospective study involved a case series of nine patients who underwent mandibular reconstruction between 2015 and 2017. The modular protocol comprised three novel modifications in terms of computer-assisted surgical simulation (CASS); surgical template (ST), and surgical procedure. Read More

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http://dx.doi.org/10.1016/j.jcms.2018.10.002DOI Listing
January 2019
7 Reads

Oropharyngeal swallowing function in patients with presbyphagia.

J Phys Ther Sci 2018 Nov 6;30(11):1357-1358. Epub 2018 Nov 6.

Department of Emergency Medical Services, Kyungdong University: 815 Gyeonhwon-ro, Munmak-eup, Wonju-si, Gangwon-do, Republic of Korea.

[Purpose] This study investigated the characteristics of oropharyngeal swallowing function in patients with presbyphagia. [Participants and Methods] Data for 25 patients with presbyphagia were retrospectively analyzed. The oropharyngeal swallowing function was evaluated using VDS based on videofluoroscopic swallowing study. Read More

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http://dx.doi.org/10.1589/jpts.30.1357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220106PMC
November 2018
9 Reads

Craniofacial abnormality with skeletal dysplasia in mice lacking chondroitin sulfate N-acetylgalactosaminyltransferase-1.

Sci Rep 2018 Nov 20;8(1):17134. Epub 2018 Nov 20.

Department of Medical Cell Biology, School of Medicine, Aichi Medical University, Nagakute, Aichi, 480-1195, Japan.

Chondroitin sulfate (CS) proteoglycan is a major component of the extracellular matrix and plays an important part in organogenesis. To elucidate the roles of CS for craniofacial development, we analyzed the craniofacial morphology in CS N-acetylgalactosaminyltransferase-1 (T1) gene knockout (KO) mice. T1KO mice showed the impaired intramembranous ossification in the skull, and the final skull shape of adult mice included a shorter face, higher and broader calvaria. Read More

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http://dx.doi.org/10.1038/s41598-018-35412-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244165PMC
November 2018
12 Reads

A comparison between modified and conventional surgical techniques for surgical lip repositioning in the management of the gummy smile.

J Esthet Restor Dent 2018 Nov 9;30(6):523-531. Epub 2018 Nov 9.

Oral Medicine Department, Faculty of Dental Medicine - Damascus University, Damascus, Syria.

Aim: The aim of this study was to evaluate and compare conventional and modified lip repositioning surgical techniques used for management of gummy smile involving hyperactive lip elevator muscles.

Methods And Materials: A prospective study was conducted between April 2016 and May 2017. Twenty two adult patients aged 18-38 years with gummy smile ranging from 4 to 6 mm because of soft tissue disorders were included in the study. Read More

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http://dx.doi.org/10.1111/jerd.12433DOI Listing
November 2018
1 Read

Linking Enzymatic Oxidative Degradation of Lignin to Organics Detoxification.

Int J Mol Sci 2018 Oct 28;19(11). Epub 2018 Oct 28.

Key Laboratory for Feed Biotechnology of the Ministry of Agriculture, Feed Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China.

The major enzymes involved in lignin degradation are laccase, class II peroxidases (lignin peroxidase, manganese peroxidase, and versatile peroxidase) and dye peroxidase, which use an oxidative or peroxidative mechanism to deconstruct the complex and recalcitrant lignin. Laccase and manganese peroxidase directly oxidize phenolic lignin components, while lignin peroxidase and versatile peroxidase can act on the more recalcitrant non-phenolic lignin compounds. Mediators or co-oxidants not only increase the catalytic ability of these enzymes, but also largely expand their substrate scope to those with higher redox potential or more complicated structures. Read More

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http://www.mdpi.com/1422-0067/19/11/3373
Publisher Site
http://dx.doi.org/10.3390/ijms19113373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274955PMC
October 2018
12 Reads

Diagnosis and Treatment of Orofacial Granulomatosis.

J Dent Child (Chic) 2018 May;85(2):83-87

Department of Oral and Maxillofacial Surgery, Oulu University Hospital and Department of Periodontology and Geriatric Dentistry, Unit of Oral Health Sciences, University of Oulu, Oulu, Finland.

Orofacial granulomatosis (OFG) is a chronic inflammatory disorder characterized by lip swelling and gingival alterations. OFG occurs either as a separate clinical entity or associated with a systemic disorder such as Crohn's disease (CD). The purpose of this paper is to report the case of a 13-year old boy who presented with marked granulomatous gingival inflammation and stomach discomfort. Read More

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May 2018
5 Reads

Management of atrial fibrillation: easy as ABC.

Minerva Med 2019 Feb 11;110(1):27-34. Epub 2018 Oct 11.

Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UK -

Atrial fibrillation (AF) is the commonest sustained arrhythmia with increasing incidence worldwide. AF is a major cause of morbidity (resulting from heart failure, stroke and hospitalization) and mortality. The aim of primary and specialist care is to improve patient outcome through early detection of AF and optimal clinical management. Read More

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https://www.minervamedica.it/index2.php?show=R10Y9999N00A181
Publisher Site
http://dx.doi.org/10.23736/S0026-4806.18.05824-XDOI Listing
February 2019
13 Reads

Bilateral suprazygomatic maxillary nerve blocks vs. infraorbital and palatine nerve blocks in cleft lip and palate repair: A double-blind, randomised study.

Eur J Anaesthesiol 2019 01;36(1):40-47

From the Department of Anesthesiology, Vall d'Hebron Hospital, Department of Surgery, Universitat Autònoma de Barcelona, Barcelona, Spain (GE, MDM, MdN), Department of Anesthesiology, Children's Hospital Colorado, Denver, Colorado, USA (GM, CC, RJI), Department of Pediatric Anesthesia, King Abdullah Hospital, Riyadh, Saudi Arabia (PS), Department of Anesthesiology, Guwahati Comprehensive Cleft Care Center, Guwahati, India (PB, NB) and Department Anesthesiology and Pain Management, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA (AB).

Background: Cleft defects are common craniofacial malformations which require early surgical repair. These patients are at high risk of postoperative airway obstruction and respiratory failure. Cleft surgery may require high doses of opioids which may contribute to these complications. Read More

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http://Insights.ovid.com/crossref?an=00003643-900000000-9852
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http://dx.doi.org/10.1097/EJA.0000000000000900DOI Listing
January 2019
7 Reads

Google Trends as a Tool for Evaluating Public Interest in Facial Cosmetic Procedures.

Aesthet Surg J 2018 Oct 10. Epub 2018 Oct 10.

Division of Plastic Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA.

Background: The utility of Google Trends (GT) in analyzing worldwide and regional patient interest for plastic surgery procedures is becoming invaluable to plastic surgery practices. GT data may offer practical information to plastic surgeons pertaining to seasonal and geographic trends in interest in facial cosmetic procedures.

Objective: The authors sought to analyze geographic and temporal trends between GT search volumes and US surgery volumes using univariate analysis. Read More

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https://academic.oup.com/asj/advance-article/doi/10.1093/asj
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http://dx.doi.org/10.1093/asj/sjy267DOI Listing
October 2018
6 Reads

Impact of face proportions on face attractiveness.

J Cosmet Dermatol 2018 Dec 5;17(6):954-959. Epub 2018 Oct 5.

Department of Aesthetic Medicine, Medical University of Białystok, Białystok, Poland.

Background: Proportions of face components appear to play a role in facial attractiveness.

Aims: The aim of the study was to establish the best proportions of face components in relation to whole face shape for facial attractiveness.

Methods: Only one face component (eye, nose, or lips) of a model in a series of photographs was altered using a computer program. Read More

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http://doi.wiley.com/10.1111/jocd.12783
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http://dx.doi.org/10.1111/jocd.12783DOI Listing
December 2018
11 Reads

Face-neck lifting and ancillary procedures: A series of 203 cases.

Medicine (Baltimore) 2018 Sep;97(39):e12333

Professor of Plastic Surgery, A-Plast Estetik, Istanbul, Turkey.

Various methods and ancillary procedures have been defined in the era of face-lifting surgery.The purpose of this study was to evaluate the esthetic outcomes of our face-neck cases and the importance of adding ancillary procedures based on individual assessment.We conducted a retrospective review of 203 face-neck cases, basically following the endoscopic and open principles of Vasconez. Read More

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http://Insights.ovid.com/crossref?an=00005792-201809280-0003
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http://dx.doi.org/10.1097/MD.0000000000012333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181572PMC
September 2018
6 Reads

[Morphological and functional peri-oral changes during early treatment of Class II division 1 malocclusions using EF Line functional education devices].

Orthod Fr 2018 09 26;89(3):289-306. Epub 2018 Sep 26.

49 avenue Saint-Charles, 34090 Montpellier, France.

Introduction: The aim of this article was to assess the impact of a flexible functional education splint for interceptive treatment of Class II division 1 dysmorphoses.

Materials And Methods: An observational, prospective, multi-center non-comparative EGIDYS study was conducted in 81 children with a Class II division 1 malocclusion presenting one or several functional disorders. Patients wore a flexible splint in the EF Line range for a minimum of two hours per day and all night over 12 months in combination with educational exercises depending on the case. Read More

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http://dx.doi.org/10.1051/orthodfr/2018025DOI Listing
September 2018

Temporomandibular joint anterior disc displacement with reduction in a young population: Prevalence and risk indicators.

Int J Paediatr Dent 2019 Jan 14;29(1):66-73. Epub 2018 Sep 14.

Department of Oral Kinesiology, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

Background: Temporomandibular joint (TMJ) anterior disc displacements with reduction (ADDR) are commonly found in the young population and often found to be associated with biomechanical and anatomical factors. Until now, most knowledge on ADDR among children and adolescents comes from studies performed on Caucasian subjects.

Aims: To assess the clinically determined prevalence rates of ADDR among the young Indonesian population and to evaluate its risk indicators. Read More

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http://doi.wiley.com/10.1111/ipd.12426
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http://dx.doi.org/10.1111/ipd.12426DOI Listing
January 2019
8 Reads

Biodeterioration of plasma pretreated LDPE sheets by Pleurotus ostreatus.

PLoS One 2018 13;13(9):e0203786. Epub 2018 Sep 13.

Grupo de Física-Matemática, Departamento de Matemáticas, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, D.C., Colombia.

Low-density polyethylene (LDPE) waste generates an environmental impact. To achieve the most suitable option for their degradation, it is necessary to implement chemical, physical and biological treatments, as well as combining procedures. Best treatment was prognosticated by Plackett-Burman Experimental Design (PB), evaluating five factors with two levels (0. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0203786PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136779PMC
March 2019
8 Reads

Rectal Cancer: Redox State of Venous Blood and Tissues of Blood Vessels from Electron Paramagnetic Resonance and Its Correlation with the Five-Year Survival.

Biomed Res Int 2018 13;2018:4848652. Epub 2018 Aug 13.

R.E. Kavetsky institute of Experimental Pathology, Oncology and Radiobiology NAS of Ukraine, Kyiv, Ukraine.

A role of pro- and antioxidants for reducing rectal cancer (RC) incidence in operative, preoperative, and postoperative treatments is still disputable and controversial. The redox state of venous blood and tissues of blood vessels of 60 patients with RC (TNMG) and 20 donors is studied by means of the conventional and spin-trapping electron paramagnetic resonance (EPR). The intensity of the signals from ceruloplasmin (CP), transferrin (TF), and labile iron pool (LIP) at temperature T = 77 K as well as superoxide generation rate and nitric oxide (NO) levels at T = 300 K is measured. Read More

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https://www.hindawi.com/journals/bmri/2018/4848652/
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http://dx.doi.org/10.1155/2018/4848652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110006PMC
December 2018
11 Reads

ESC Council on hypertension position document on the management of hypertensive emergencies.

Eur Heart J Cardiovasc Pharmacother 2019 01;5(1):37-46

University College London (UCL) and UCL Hospitals, London, UK.

Hypertensive emergencies are those situations where very high blood pressure (BP) values are associated with acute organ damage, and therefore, require immediate, but careful, BP reduction. The type of acute organ damage is the principal determinant of: (i) the drug of choice, (ii) the target BP, and (iii) the timeframe in which BP should be lowered. Key target organs are the heart, retina, brain, kidneys, and large arteries. Read More

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http://dx.doi.org/10.1093/ehjcvp/pvy032DOI Listing
January 2019
61 Reads

Surgical correction of hypertrophic upper lip in vascular malformations.

J Craniomaxillofac Surg 2018 Oct 3;46(10):1790-1792. Epub 2018 Aug 3.

University of Milan, Department of Maxillo-Facial Surgery, San Paolo Hospital (Head: Prof. F. Biglioli), Milan, Italy.

Capillary malformations (CMs) and Lymphatic malformations (LMs) are vascular malformations that share a common tendency to cause soft and hard tissue hypertrophy, expressed in the three dimensions of the space. The middle third of the face is the most commonly involved area, with a predominance of the upper lip. To our knowledge, no paper has previously focused on the surgical technique to correct such deformities. Read More

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http://dx.doi.org/10.1016/j.jcms.2018.07.023DOI Listing
October 2018
1 Read

Candida species biotypes in the oral cavity of infants and children with orofacial clefts under surgical rehabilitation.

Microb Pathog 2018 Nov 20;124:203-215. Epub 2018 Aug 20.

Laboratory of Microbiology and Immunology, Department of Oral Diagnosis, Dental School of Piracicaba, State University of Campinas (FOP/UNICAMP), Piracicaba, 13414-903, SP, Brazil; Laboratory of Pharmacogenetics and Molecular Biology, Faculty of Medical Sciences, University of Alfenas (UNIFENAS), Alfenas, 37132-440, MG, Brazil.

Patients with orofacial clefts present various risk factors for oral infectious diseases, resulting from anatomical and physiological changes and those resulting from rehabilitating therapeutic interventions. The incidence of Candida species in groups of babies and children with orofacial clefts, during pre- and post-operative periods and until return to first consultation, and the profiles for antifungal sensitivity and virulence in vitro were investigated. Oral samples were collected at different times over the surgical procedures and post-surgical clinical consultation and seeded in chromogenic culture media CHROMagar Candida. Read More

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http://dx.doi.org/10.1016/j.micpath.2018.08.042DOI Listing
November 2018
16 Reads
2.000 Impact Factor

Edoxaban in Asian Patients With Atrial Fibrillation: Effectiveness and Safety.

J Am Coll Cardiol 2018 Aug;72(8):838-853

Institute of Cardiovascular Sciences, University of Birmingham, United Kingdom; Liverpool Centre for Cardiovascular Science, University of Liverpool, United Kingdom; Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.

Background: It is unclear whether edoxaban shows better risk reduction of ischemic stroke, bleeding, and all-cause mortality than warfarin in Asian patients with nonvalvular atrial fibrillation (AF).

Objectives: This study compared the effectiveness and safety of edoxaban with those of warfarin in a Korean population with AF.

Methods: Using the Korean National Health Insurance Service database, we included new users of edoxaban and warfarin in patients with AF from January 2014 to December 2016 (n = 4,200 on edoxaban, and n = 31,565 on warfarin) and analyzed the risk of ischemic stroke, intracranial hemorrhage (ICH), hospitalization for gastrointestinal (GI) bleeding, hospitalization for major bleeding, and all-cause death. Read More

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http://dx.doi.org/10.1016/j.jacc.2018.05.066DOI Listing
August 2018
10 Reads

Tongue Reduction Surgery and Feeding Difficulties in Infants With Beckwith Wiedemann Syndrome: A Case Series.

Cleft Palate Craniofac J 2018 Aug 15:1055665618794070. Epub 2018 Aug 15.

2 Centre for Outcomes and Experience Research in Children's Health, Illness and Disability (ORCHID), Great Ormond Street Hospital, London, United Kingdom.

Objective: To profile the pre- and post-operative feeding difficulties in infants with macroglossia in Beckwith Wiedemann Syndrome (m-BWS) who have had tongue reduction surgery (TRS) and to pilot a bespoke feeding rating scale.

Design: Retrospective consecutive case series designed with two pre-operative and one 3-month post-operative feeding assessments. A 4-point Likert-type scale was developed and applied retrospectively to describe the feeding behaviors for liquids, purées, and solids. Read More

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http://dx.doi.org/10.1177/1055665618794070DOI Listing
August 2018
3 Reads

Facilitating CAD/CAM nasoalveolar molding therapy with a novel click-in system for nasal stents ensuring a quick and user-friendly chairside nasal stent exchange.

Sci Rep 2018 Aug 14;8(1):12084. Epub 2018 Aug 14.

Institute of Medical and Polymer Engineering, Technische Universität München, München, Germany.

Nasoalveolar molding (NAM) aims to improve nasal symmetry with a nasal stent in cleft lip and palate (CLP) patients. When plates have to be exchanged because of dentoalveolar growth or cleft reduction, the nasal stent has to be mounted onto a new plate. This procedure elongates visiting hours for patients and parents or requires second treatment sessions. Read More

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http://dx.doi.org/10.1038/s41598-018-29960-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092331PMC
August 2018
3 Reads

Survival probabilities and trends for lip, oral cavity and oropharynx cancers in Northern Portugal in the period 2000-2009.

Ecancermedicalscience 2018 31;12:855. Epub 2018 Jul 31.

King's College London and WHO Collaborating Centre for Oral Cancer, London SE5 9RW, UK.

Background: Oral cancer represents a serious public health problem worldwide. Our aim was to analyse the survival probabilities and trends of patients presenting with lip, oral cavity and oropharynx cancers, who were residents in the north of Portugal.

Methods: Using cancer-registry data, we conducted a population-based study of lip, oral cavity and oropharynx cancers diagnosed in the period 2000-2009, among residents in the north of Portugal. Read More

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http://dx.doi.org/10.3332/ecancer.2018.855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070366PMC
July 2018
2 Reads

Clustering-based preprocessing method for lipidomic data analysis: application for the evolution of newborn skin surface lipids from birth until 6 months.

Anal Bioanal Chem 2018 Oct 4;410(25):6517-6528. Epub 2018 Aug 4.

Lip(Sys)2- Chimie Analytique Pharmaceutique (FKA EA4041 Groupe de Chimie Analytique de Paris-Sud), University Paris-Sud 11, Université Paris-Saclay, 5 rue Jean Baptiste Clément, 92290, Châtenay-Malabry, France.

After life in utero and birth, the skin is submitted to an important process of adaptation to a relatively dry gaseous environment. Skin surface lipids (SSLs) contribute actively to the protection of the skin barrier. Within this context, our objective was to study the evolution of each lipid compound during the postnatal period. Read More

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http://dx.doi.org/10.1007/s00216-018-1255-8DOI Listing
October 2018
10 Reads

A specific protocol of myo-functional therapy in children with Down syndrome. A pilot study.

Eur J Paediatr Dent 2018 Sep;19(3):243-246

ENT, Head and Neck Department - Università Cattolica del Sacro Cuore.

In this article the authors propose a specific myofunctional therapy protocol for children with Down syndrome. For these patients, who usually present with atypical swallowing problems, mouth breathing and lip incompetence, the use of a myofunctional therapy protocol with specific exercises has been shown to improve orofacial and nasal functions. In addition to the functional results, such as the correction of the atypical swallowing, restoration of lip competence, breathing improvement and reduction of nasal rhinorrhea, there were also aesthetic results. Read More

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http://ejpd.eu/EJPD_2018_19_3_14.pdf
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http://dx.doi.org/10.23804/ejpd.2018.19.03.14DOI Listing
September 2018
1 Read

Lifestyle Intervention in Danish Obese Pregnant Women With Early Gestational Diabetes Mellitus According to WHO 2013 Criteria Does Not Change Pregnancy Outcomes: Results From the LiP (Lifestyle in Pregnancy) Study.

Diabetes Care 2018 10 30;41(10):2079-2085. Epub 2018 Jul 30.

Department of Gynecology and Obstetrics, Odense University Hospital, Odense, Denmark.

Objective: To study effects of lifestyle intervention on metabolic and clinical outcomes in obese women fulfilling the World Health Organization (WHO) 2013 diagnostic criteria for gestational diabetes mellitus (GDM) in early gestation.

Research Design And Methods: Secondary analysis of data from the Lifestyle in Pregnancy (LiP) study, a lifestyle randomized controlled trial in 304 pregnant women with BMI ≥30 kg/m. Early GDM (week 12-15) was diagnosed according to modified WHO 2013 GDM criteria: fasting venous plasma glucose ≥5. Read More

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http://dx.doi.org/10.2337/dc18-0808DOI Listing
October 2018
3 Reads

Open Reduction Internal Fixation With Transverse Volar Plating for Unstable Proximal Interphalangeal Fracture-Dislocation: The Seatbelt Procedure.

Hand (N Y) 2018 Jul 28:1558944718790063. Epub 2018 Jul 28.

1 Duke University Medical Center, Durham, NC, USA.

Background: Unstable intra-articular proximal interphalangeal (PIP) joint fracture-dislocations present a difficult problem that requires congruous joint reduction and stable internal fixation or distraction. Though fractures with limited articular involvement may be treated successfully with less invasive procedures, fracture-dislocations with a volar shear component may benefit from joint reduction with subchondral support for maintenance of stability. The purpose of this article is to describe a volar transverse plate and screw technique and report the short-term postoperative results. Read More

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http://dx.doi.org/10.1177/1558944718790063DOI Listing
July 2018
4 Reads

Estimated Effectiveness and Safety of Nonvitamin K Antagonist Oral Anticoagulants Compared With Optimally Acenocoumarol Anticoagulated "Real-World" in Patients With Atrial Fibrillation.

Am J Cardiol 2018 Sep 2;122(5):785-792. Epub 2018 Jun 2.

Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, United Kingdom; Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.

Nonvitamin K antagonist oral anticoagulants (NOACs) have been proposed as an alternative to vitamin K antagonists in atrial fibrillation (AF) patients but the comparative benefits between NOACs and optimally anticoagulated patients is unknown. We estimated the absolute benefit in clinical outcomes rates of real-world effect of NOACs in optimally anticoagulated AF patients with acenocoumarol. We included 1,361 patients stable on acenocoumarol with time in therapeutic range of 100% and 6. Read More

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http://dx.doi.org/10.1016/j.amjcard.2018.05.012DOI Listing
September 2018
3 Reads

Glucolipotoxic conditions induce β-cell iron import, cytosolic ROS formation and apoptosis.

J Mol Endocrinol 2018 Aug;61(2):69-77

Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.

Type 2 diabetes (T2D) arises when the pancreatic beta-cell fails to compensate for increased insulin needs due to insulin resistance. Glucolipotoxicity (GLT) has been proposed to induce beta-cell dysfunction in T2D by formation of reactive oxygen species (ROS). Here, we examined if modeling glucolipotoxic conditions by high glucose-high free fatty acid (FFA) exposure (GLT) regulates beta-cell iron transport, by increasing the cytosolic labile iron pool (LIP). Read More

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http://dx.doi.org/10.1530/JME-17-0262DOI Listing
August 2018
5 Reads
3.081 Impact Factor

Post-surgical effects on the maxillary segments of children with oral clefts: New three-dimensional anthropometric analysis.

J Craniomaxillofac Surg 2018 Sep 30;46(9):1511-1514. Epub 2018 Jun 30.

Department of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, and Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, SP, Brazil. Electronic address:

This study aimed to use new three-dimensional (3D) anthropometric analyses to verify the post-surgical effects on the maxillary segments of children with unilateral cleft lip and palate. The sample was composed by digitized dental models of 60 children with unilateral complete cleft lip and alveolus (UCLA) and complete unilateral cleft lip and palate (UCLP). The impressions were taken before cheiloplasty (T1), after cheiloplasty (T2), and after palatoplasty (T3). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10105182183047
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http://dx.doi.org/10.1016/j.jcms.2018.06.017DOI Listing
September 2018
2 Reads

A centralized automated-dispensing system in a French teaching hospital: return on investment and quality improvement.

Int J Qual Health Care 2018 Jul 11. Epub 2018 Jul 11.

Pharmacy Department, Hôpital Européen Georges Pompidou, APHP, 20 Rue Leblanc, Paris, France.

Objectives: To evaluate the return on investment (ROI) and quality improvement after implementation of a centralized automated-dispensing system after 8 years of use.

Design: Prospective evaluation of ROI; before and after study to evaluate dispensing errors; user satisfaction questionnaire after 8 years of use.

Setting: The study was conducted at a French teaching hospital in the pharmacy department, which is equipped with decentralized automated medication cabinets in the wards. Read More

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http://dx.doi.org/10.1093/intqhc/mzy152DOI Listing
July 2018
12 Reads