1,468 results match your criteria Lip Reduction


Evaluation of a Medicaid Lock-in Program: Increased Use of Opioid Use Disorder Treatment but No Impact on Opioid Overdose Risk.

Med Care 2019 Jan 8. Epub 2019 Jan 8.

Duke Clinical Research Institute, Durham, NC.

Background: "Lock-in" programs (LIPs) identify beneficiaries demonstrating potential overutilization of opioids, and other controlled substances, and restrict their access to these medications. LIPs are expanding to address the opioid crisis and could be an effective tool for connecting people to opioid use disorder treatment. We examined the immediate and sustained effects of a Medicaid LIP on overdose risk and use of medication-assisted treatment (MAT) for opioid use disorder. Read More

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http://dx.doi.org/10.1097/MLR.0000000000001058DOI Listing
January 2019
2 Reads

[Imaging for treatment planning in lipo-and lymphedema].

Handchir Mikrochir Plast Chir 2018 Dec 8;50(6):386-392. Epub 2019 Jan 8.

Universitätsklinikum Erlangen Plastisch- und Handchirurgische.

Lipoedema is a progressive disease, which predominantly affects women. It is characterised by circumferential growth, with increase in fat tissue of the extremities, and can lead to oedema. In contrast, the lymphoedema is defined by a specific lymphatic drainage disorder and can lead to fibrosis of the surrounding connective tissue. Read More

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http://dx.doi.org/10.1055/a-0739-7911DOI Listing
December 2018
2 Reads

Effectiveness and Safety of Oral Anticoagulants Among Nonvalvular Atrial Fibrillation Patients.

Stroke 2018 Dec;49(12):2933-2944

Department of Hospital Medicine, Ochsner Clinic Foundation, New Orleans, LA; and Ochsner Clinical School, University of Queensland School of Medicine, New Orleans, LA (S.D.).

Background and Purpose- This ARISTOPHANES study (Anticoagulants for Reduction in Stroke: Observational Pooled Analysis on Health Outcomes and Experience of Patients) used multiple data sources to compare stroke/systemic embolism (SE) and major bleeding (MB) among a large number of nonvalvular atrial fibrillation patients on non-vitamin K antagonist oral anticoagulants (NOACs) or warfarin. Methods- A retrospective observational study of nonvalvular atrial fibrillation patients initiating apixaban, dabigatran, rivaroxaban, or warfarin from January 1, 2013, to September 30, 2015, was conducted pooling Centers for Medicare and Medicaid Services Medicare data and 4 US commercial claims databases. After 1:1 NOAC-warfarin and NOAC-NOAC propensity score matching in each database, the resulting patient records were pooled. Read More

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.118.020232
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http://dx.doi.org/10.1161/STROKEAHA.118.020232DOI Listing
December 2018
2 Reads

Redox potential increased during the evolution of enzymes degrading recalcitrant lignin.

Chemistry 2018 Dec 19. Epub 2018 Dec 19.

Consejo Superior de Investigaciones Cientificas CSIC, Centro de Investigaciones Biologicas CIB, Ramiro de Maeztu 9, 28040, Madrid, SPAIN.

To investigate how ligninolytic peroxidases acquired the uniquely high redox-potential they show today, their ancestors were resurrected and characterized. Unfortunately, the transient Compounds I (CI) and II (CII) from peroxide activation of the enzyme resting state (RS) are unstable. Therefore, the reduction potentials (Eº') of the three redox-couples (CI/RS, CI/CII and CII/RS) were estimated (for the first time in a ligninolytic peroxidase) from equilibria concentrations analyzed by stopped-flow UV/vis spectroscopy. Read More

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http://doi.wiley.com/10.1002/chem.201805679
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http://dx.doi.org/10.1002/chem.201805679DOI Listing
December 2018
1 Read

"Pro-bird" floral traits discourage bumblebee visits to Penstemon gentianoides (Plantaginaceae), a mixed-pollinated herb.

Naturwissenschaften 2018 Dec 17;106(1-2). Epub 2018 Dec 17.

Departamento de Biología Evolutiva, Instituto de Ecología, AC (INECOL), Carretera Antigua a Coatepec No. 351, El Haya, Xalapa, 91070, Veracruz, Mexico.

The pollination syndrome concept implies that flowers evolved with particular sets of characteristics, such as colors, shapes, orientations, and rewards, as a means of attracting pollinators. However, these traits may have also evolved to deter unwanted visitors. The North American genus Penstemon exhibits a great floral diversity that is mainly associated with bumblebee and hummingbird pollination. Read More

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http://dx.doi.org/10.1007/s00114-018-1595-4DOI Listing
December 2018

Efficacy of Platelet-Rich Fibrin Combined with Autogenous Bone Graft in the Quality and Quantity of Maxillary Alveolar Cleft Reconstruction.

Iran J Otorhinolaryngol 2018 Nov;30(101):329-334

Department of Oral and Maxillofacial Surgery, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.

Introduction: The aim of this study was to evaluate the effect of platelet-rich fibrin (PRF) on the quality and quantity of bone formation in unilateral maxillary alveolar cleft reconstruction using cone beam computed tomography.

Materials And Methods: This study was conducted on 10 non-syndromic patients with unilateral cleft lip and palate within the age group of 9-12 years. The study population was randomly assigned into two groups of PRF and control, each of which entailed 5 cases. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291813PMC
November 2018

Surgical Correction of Double Upper Lip Deformities Without Mucosal Excision: A Transvestibular Approach.

Int J Periodontics Restorative Dent 2019 Jan/Feb;39(1):49-54

Double lip is a rare deformity that mainly affects the upper lip. The typical clinical image involves bilateral mucosal pads separated by a central groove that appear superimposed over the maxillary incisors. The deformity is rather noticeable and esthetically disturbing. Read More

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http://dx.doi.org/10.11607/prd.3450DOI Listing
December 2018

Evaluation of accuracy and sensory outcomes of mandibular reconstruction using computer-assisted surgical simulation.

J Craniomaxillofac Surg 2019 Jan 11;47(1):6-14. Epub 2018 Oct 11.

Department of Oral and Maxillofacial Surgery, Ninth People's Hospital, Collage of Stomatology, Shanghai JiaoTong University School of Medicine, Shanghai, China. Electronic address:

Purpose: To introduce a modified protocol for mandibular reconstruction and evaluate the protocol using a standardized assessment method.

Method: This retrospective study involved a case series of nine patients who underwent mandibular reconstruction between 2015 and 2017. The modular protocol comprised three novel modifications in terms of computer-assisted surgical simulation (CASS); surgical template (ST), and surgical procedure. Read More

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http://dx.doi.org/10.1016/j.jcms.2018.10.002DOI Listing
January 2019
3 Reads

Oropharyngeal swallowing function in patients with presbyphagia.

J Phys Ther Sci 2018 Nov 6;30(11):1357-1358. Epub 2018 Nov 6.

Department of Emergency Medical Services, Kyungdong University: 815 Gyeonhwon-ro, Munmak-eup, Wonju-si, Gangwon-do, Republic of Korea.

[Purpose] This study investigated the characteristics of oropharyngeal swallowing function in patients with presbyphagia. [Participants and Methods] Data for 25 patients with presbyphagia were retrospectively analyzed. The oropharyngeal swallowing function was evaluated using VDS based on videofluoroscopic swallowing study. Read More

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http://dx.doi.org/10.1589/jpts.30.1357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220106PMC
November 2018
5 Reads

Craniofacial abnormality with skeletal dysplasia in mice lacking chondroitin sulfate N-acetylgalactosaminyltransferase-1.

Sci Rep 2018 Nov 20;8(1):17134. Epub 2018 Nov 20.

Department of Medical Cell Biology, School of Medicine, Aichi Medical University, Nagakute, Aichi, 480-1195, Japan.

Chondroitin sulfate (CS) proteoglycan is a major component of the extracellular matrix and plays an important part in organogenesis. To elucidate the roles of CS for craniofacial development, we analyzed the craniofacial morphology in CS N-acetylgalactosaminyltransferase-1 (T1) gene knockout (KO) mice. T1KO mice showed the impaired intramembranous ossification in the skull, and the final skull shape of adult mice included a shorter face, higher and broader calvaria. Read More

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http://dx.doi.org/10.1038/s41598-018-35412-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244165PMC
November 2018
6 Reads

A comparison between modified and conventional surgical techniques for surgical lip repositioning in the management of the gummy smile.

J Esthet Restor Dent 2018 Nov 9;30(6):523-531. Epub 2018 Nov 9.

Oral Medicine Department, Faculty of Dental Medicine - Damascus University, Damascus, Syria.

Aim: The aim of this study was to evaluate and compare conventional and modified lip repositioning surgical techniques used for management of gummy smile involving hyperactive lip elevator muscles.

Methods And Materials: A prospective study was conducted between April 2016 and May 2017. Twenty two adult patients aged 18-38 years with gummy smile ranging from 4 to 6 mm because of soft tissue disorders were included in the study. Read More

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http://dx.doi.org/10.1111/jerd.12433DOI Listing
November 2018

Diagnosis and Treatment of Orofacial Granulomatosis.

J Dent Child (Chic) 2018 May;85(2):83-87

Department of Oral and Maxillofacial Surgery, Oulu University Hospital and Department of Periodontology and Geriatric Dentistry, Unit of Oral Health Sciences, University of Oulu, Oulu, Finland.

Orofacial granulomatosis (OFG) is a chronic inflammatory disorder characterized by lip swelling and gingival alterations. OFG occurs either as a separate clinical entity or associated with a systemic disorder such as Crohn's disease (CD). The purpose of this paper is to report the case of a 13-year old boy who presented with marked granulomatous gingival inflammation and stomach discomfort. Read More

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May 2018
1 Read

Management of atrial fibrillation: easy as ABC.

Minerva Med 2018 Oct 11. Epub 2018 Oct 11.

Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UK -

Atrial fibrillation (AF) is the commonest sustained arrhythmia with increasing incidence worldwide. AF is a major cause of morbidity (resulting from heart failure, stroke and hospitalisation) and mortality. The aim of primary and specialist care is to improve patient outcome through early detection of AF and optimal clinical management. Read More

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https://www.minervamedica.it/index2.php?show=R10Y9999N00A181
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http://dx.doi.org/10.23736/S0026-4806.18.05824-XDOI Listing
October 2018
7 Reads

Bilateral suprazygomatic maxillary nerve blocks vs. infraorbital and palatine nerve blocks in cleft lip and palate repair: A double-blind, randomised study.

Eur J Anaesthesiol 2019 Jan;36(1):40-47

From the Department of Anesthesiology, Vall d'Hebron Hospital, Department of Surgery, Universitat Autònoma de Barcelona, Barcelona, Spain (GE, MDM, MdN), Department of Anesthesiology, Children's Hospital Colorado, Denver, Colorado, USA (GM, CC, RJI), Department of Pediatric Anesthesia, King Abdullah Hospital, Riyadh, Saudi Arabia (PS), Department of Anesthesiology, Guwahati Comprehensive Cleft Care Center, Guwahati, India (PB, NB) and Department Anesthesiology and Pain Management, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA (AB).

Background: Cleft defects are common craniofacial malformations which require early surgical repair. These patients are at high risk of postoperative airway obstruction and respiratory failure. Cleft surgery may require high doses of opioids which may contribute to these complications. Read More

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http://Insights.ovid.com/crossref?an=00003643-900000000-9852
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http://dx.doi.org/10.1097/EJA.0000000000000900DOI Listing
January 2019
6 Reads

Google Trends as a Tool for Evaluating Public Interest in Facial Cosmetic Procedures.

Aesthet Surg J 2018 Oct 10. Epub 2018 Oct 10.

Division of Plastic Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA.

Background: The utility of Google Trends (GT) in analyzing worldwide and regional patient interest for plastic surgery procedures is becoming invaluable to plastic surgery practices. GT data may offer practical information to plastic surgeons pertaining to seasonal and geographic trends in interest in facial cosmetic procedures.

Objective: The authors sought to analyze geographic and temporal trends between GT search volumes and US surgery volumes using univariate analysis. Read More

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https://academic.oup.com/asj/advance-article/doi/10.1093/asj
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http://dx.doi.org/10.1093/asj/sjy267DOI Listing
October 2018
4 Reads

Impact of face proportions on face attractiveness.

J Cosmet Dermatol 2018 Dec 5;17(6):954-959. Epub 2018 Oct 5.

Department of Aesthetic Medicine, Medical University of Białystok, Białystok, Poland.

Background: Proportions of face components appear to play a role in facial attractiveness.

Aims: The aim of the study was to establish the best proportions of face components in relation to whole face shape for facial attractiveness.

Methods: Only one face component (eye, nose, or lips) of a model in a series of photographs was altered using a computer program. Read More

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http://doi.wiley.com/10.1111/jocd.12783
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http://dx.doi.org/10.1111/jocd.12783DOI Listing
December 2018
8 Reads

Face-neck lifting and ancillary procedures: A series of 203 cases.

Medicine (Baltimore) 2018 Sep;97(39):e12333

Professor of Plastic Surgery, A-Plast Estetik, Istanbul, Turkey.

Various methods and ancillary procedures have been defined in the era of face-lifting surgery.The purpose of this study was to evaluate the esthetic outcomes of our face-neck cases and the importance of adding ancillary procedures based on individual assessment.We conducted a retrospective review of 203 face-neck cases, basically following the endoscopic and open principles of Vasconez. Read More

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http://Insights.ovid.com/crossref?an=00005792-201809280-0003
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http://dx.doi.org/10.1097/MD.0000000000012333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181572PMC
September 2018
5 Reads

[Morphological and functional peri-oral changes during early treatment of Class II division 1 malocclusions using EF Line functional education devices].

Orthod Fr 2018 09 26;89(3):289-306. Epub 2018 Sep 26.

49 avenue Saint-Charles, 34090 Montpellier, France.

Introduction: The aim of this article was to assess the impact of a flexible functional education splint for interceptive treatment of Class II division 1 dysmorphoses.

Materials And Methods: An observational, prospective, multi-center non-comparative EGIDYS study was conducted in 81 children with a Class II division 1 malocclusion presenting one or several functional disorders. Patients wore a flexible splint in the EF Line range for a minimum of two hours per day and all night over 12 months in combination with educational exercises depending on the case. Read More

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http://dx.doi.org/10.1051/orthodfr/2018025DOI Listing
September 2018

Temporomandibular joint anterior disc displacement with reduction in a young population: Prevalence and risk indicators.

Int J Paediatr Dent 2019 Jan 14;29(1):66-73. Epub 2018 Sep 14.

Department of Oral Kinesiology, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

Background: Temporomandibular joint (TMJ) anterior disc displacements with reduction (ADDR) are commonly found in the young population and often found to be associated with biomechanical and anatomical factors. Until now, most knowledge on ADDR among children and adolescents comes from studies performed on Caucasian subjects.

Aims: To assess the clinically determined prevalence rates of ADDR among the young Indonesian population and to evaluate its risk indicators. Read More

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http://doi.wiley.com/10.1111/ipd.12426
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http://dx.doi.org/10.1111/ipd.12426DOI Listing
January 2019
7 Reads

Rectal Cancer: Redox State of Venous Blood and Tissues of Blood Vessels from Electron Paramagnetic Resonance and Its Correlation with the Five-Year Survival.

Biomed Res Int 2018 13;2018:4848652. Epub 2018 Aug 13.

R.E. Kavetsky institute of Experimental Pathology, Oncology and Radiobiology NAS of Ukraine, Kyiv, Ukraine.

A role of pro- and antioxidants for reducing rectal cancer (RC) incidence in operative, preoperative, and postoperative treatments is still disputable and controversial. The redox state of venous blood and tissues of blood vessels of 60 patients with RC (TNMG) and 20 donors is studied by means of the conventional and spin-trapping electron paramagnetic resonance (EPR). The intensity of the signals from ceruloplasmin (CP), transferrin (TF), and labile iron pool (LIP) at temperature T = 77 K as well as superoxide generation rate and nitric oxide (NO) levels at T = 300 K is measured. Read More

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https://www.hindawi.com/journals/bmri/2018/4848652/
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http://dx.doi.org/10.1155/2018/4848652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110006PMC
December 2018
8 Reads

ESC Council on hypertension position document on the management of hypertensive emergencies.

Eur Heart J Cardiovasc Pharmacother 2019 01;5(1):37-46

University College London (UCL) and UCL Hospitals, London, UK.

Hypertensive emergencies are those situations where very high blood pressure (BP) values are associated with acute organ damage, and therefore, require immediate, but careful, BP reduction. The type of acute organ damage is the principal determinant of: (i) the drug of choice, (ii) the target BP, and (iii) the timeframe in which BP should be lowered. Key target organs are the heart, retina, brain, kidneys, and large arteries. Read More

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http://dx.doi.org/10.1093/ehjcvp/pvy032DOI Listing
January 2019
33 Reads

Surgical correction of hypertrophic upper lip in vascular malformations.

J Craniomaxillofac Surg 2018 Oct 3;46(10):1790-1792. Epub 2018 Aug 3.

University of Milan, Department of Maxillo-Facial Surgery, San Paolo Hospital (Head: Prof. F. Biglioli), Milan, Italy.

Capillary malformations (CMs) and Lymphatic malformations (LMs) are vascular malformations that share a common tendency to cause soft and hard tissue hypertrophy, expressed in the three dimensions of the space. The middle third of the face is the most commonly involved area, with a predominance of the upper lip. To our knowledge, no paper has previously focused on the surgical technique to correct such deformities. Read More

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http://dx.doi.org/10.1016/j.jcms.2018.07.023DOI Listing
October 2018

Candida species biotypes in the oral cavity of infants and children with orofacial clefts under surgical rehabilitation.

Microb Pathog 2018 Aug 20;124:203-215. Epub 2018 Aug 20.

Laboratory of Microbiology and Immunology, Department of Oral Diagnosis, Dental School of Piracicaba, State University of Campinas (FOP/UNICAMP), Piracicaba, 13414-903, SP, Brazil; Laboratory of Pharmacogenetics and Molecular Biology, Faculty of Medical Sciences, University of Alfenas (UNIFENAS), Alfenas, 37132-440, MG, Brazil.

Patients with orofacial clefts present various risk factors for oral infectious diseases, resulting from anatomical and physiological changes and those resulting from rehabilitating therapeutic interventions. The incidence of Candida species in groups of babies and children with orofacial clefts, during pre- and post-operative periods and until return to first consultation, and the profiles for antifungal sensitivity and virulence in vitro were investigated. Oral samples were collected at different times over the surgical procedures and post-surgical clinical consultation and seeded in chromogenic culture media CHROMagar Candida. Read More

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http://dx.doi.org/10.1016/j.micpath.2018.08.042DOI Listing
August 2018
10 Reads
2.000 Impact Factor

Edoxaban in Asian Patients With Atrial Fibrillation: Effectiveness and Safety.

J Am Coll Cardiol 2018 Aug;72(8):838-853

Institute of Cardiovascular Sciences, University of Birmingham, United Kingdom; Liverpool Centre for Cardiovascular Science, University of Liverpool, United Kingdom; Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.

Background: It is unclear whether edoxaban shows better risk reduction of ischemic stroke, bleeding, and all-cause mortality than warfarin in Asian patients with nonvalvular atrial fibrillation (AF).

Objectives: This study compared the effectiveness and safety of edoxaban with those of warfarin in a Korean population with AF.

Methods: Using the Korean National Health Insurance Service database, we included new users of edoxaban and warfarin in patients with AF from January 2014 to December 2016 (n = 4,200 on edoxaban, and n = 31,565 on warfarin) and analyzed the risk of ischemic stroke, intracranial hemorrhage (ICH), hospitalization for gastrointestinal (GI) bleeding, hospitalization for major bleeding, and all-cause death. Read More

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http://dx.doi.org/10.1016/j.jacc.2018.05.066DOI Listing
August 2018
7 Reads

Tongue Reduction Surgery and Feeding Difficulties in Infants With Beckwith Wiedemann Syndrome: A Case Series.

Cleft Palate Craniofac J 2018 Aug 15:1055665618794070. Epub 2018 Aug 15.

2 Centre for Outcomes and Experience Research in Children's Health, Illness and Disability (ORCHID), Great Ormond Street Hospital, London, United Kingdom.

Objective: To profile the pre- and post-operative feeding difficulties in infants with macroglossia in Beckwith Wiedemann Syndrome (m-BWS) who have had tongue reduction surgery (TRS) and to pilot a bespoke feeding rating scale.

Design: Retrospective consecutive case series designed with two pre-operative and one 3-month post-operative feeding assessments. A 4-point Likert-type scale was developed and applied retrospectively to describe the feeding behaviors for liquids, purées, and solids. Read More

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http://dx.doi.org/10.1177/1055665618794070DOI Listing

Facilitating CAD/CAM nasoalveolar molding therapy with a novel click-in system for nasal stents ensuring a quick and user-friendly chairside nasal stent exchange.

Sci Rep 2018 Aug 14;8(1):12084. Epub 2018 Aug 14.

Institute of Medical and Polymer Engineering, Technische Universität München, München, Germany.

Nasoalveolar molding (NAM) aims to improve nasal symmetry with a nasal stent in cleft lip and palate (CLP) patients. When plates have to be exchanged because of dentoalveolar growth or cleft reduction, the nasal stent has to be mounted onto a new plate. This procedure elongates visiting hours for patients and parents or requires second treatment sessions. Read More

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http://dx.doi.org/10.1038/s41598-018-29960-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092331PMC
August 2018
1 Read

Survival probabilities and trends for lip, oral cavity and oropharynx cancers in Northern Portugal in the period 2000-2009.

Ecancermedicalscience 2018 31;12:855. Epub 2018 Jul 31.

King's College London and WHO Collaborating Centre for Oral Cancer, London SE5 9RW, UK.

Background: Oral cancer represents a serious public health problem worldwide. Our aim was to analyse the survival probabilities and trends of patients presenting with lip, oral cavity and oropharynx cancers, who were residents in the north of Portugal.

Methods: Using cancer-registry data, we conducted a population-based study of lip, oral cavity and oropharynx cancers diagnosed in the period 2000-2009, among residents in the north of Portugal. Read More

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http://dx.doi.org/10.3332/ecancer.2018.855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070366PMC

Clustering-based preprocessing method for lipidomic data analysis: application for the evolution of newborn skin surface lipids from birth until 6 months.

Anal Bioanal Chem 2018 Oct 4;410(25):6517-6528. Epub 2018 Aug 4.

Lip(Sys)2- Chimie Analytique Pharmaceutique (FKA EA4041 Groupe de Chimie Analytique de Paris-Sud), University Paris-Sud 11, Université Paris-Saclay, 5 rue Jean Baptiste Clément, 92290, Châtenay-Malabry, France.

After life in utero and birth, the skin is submitted to an important process of adaptation to a relatively dry gaseous environment. Skin surface lipids (SSLs) contribute actively to the protection of the skin barrier. Within this context, our objective was to study the evolution of each lipid compound during the postnatal period. Read More

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http://dx.doi.org/10.1007/s00216-018-1255-8DOI Listing
October 2018
9 Reads

A specific protocol of myo-functional therapy in children with Down syndrome. A pilot study.

Eur J Paediatr Dent 2018 Sep;19(3):243-246

ENT, Head and Neck Department - Università Cattolica del Sacro Cuore.

In this article the authors propose a specific myofunctional therapy protocol for children with Down syndrome. For these patients, who usually present with atypical swallowing problems, mouth breathing and lip incompetence, the use of a myofunctional therapy protocol with specific exercises has been shown to improve orofacial and nasal functions. In addition to the functional results, such as the correction of the atypical swallowing, restoration of lip competence, breathing improvement and reduction of nasal rhinorrhea, there were also aesthetic results. Read More

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http://dx.doi.org/10.23804/ejpd.2018.19.03.14DOI Listing
September 2018

Lifestyle Intervention in Danish Obese Pregnant Women With Early Gestational Diabetes Mellitus According to WHO 2013 Criteria Does Not Change Pregnancy Outcomes: Results From the LiP (Lifestyle in Pregnancy) Study.

Diabetes Care 2018 10 30;41(10):2079-2085. Epub 2018 Jul 30.

Department of Gynecology and Obstetrics, Odense University Hospital, Odense, Denmark.

Objective: To study effects of lifestyle intervention on metabolic and clinical outcomes in obese women fulfilling the World Health Organization (WHO) 2013 diagnostic criteria for gestational diabetes mellitus (GDM) in early gestation.

Research Design And Methods: Secondary analysis of data from the Lifestyle in Pregnancy (LiP) study, a lifestyle randomized controlled trial in 304 pregnant women with BMI ≥30 kg/m. Early GDM (week 12-15) was diagnosed according to modified WHO 2013 GDM criteria: fasting venous plasma glucose ≥5. Read More

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http://dx.doi.org/10.2337/dc18-0808DOI Listing
October 2018
1 Read

Open Reduction Internal Fixation With Transverse Volar Plating for Unstable Proximal Interphalangeal Fracture-Dislocation: The Seatbelt Procedure.

Hand (N Y) 2018 Jul 28:1558944718790063. Epub 2018 Jul 28.

1 Duke University Medical Center, Durham, NC, USA.

Background: Unstable intra-articular proximal interphalangeal (PIP) joint fracture-dislocations present a difficult problem that requires congruous joint reduction and stable internal fixation or distraction. Though fractures with limited articular involvement may be treated successfully with less invasive procedures, fracture-dislocations with a volar shear component may benefit from joint reduction with subchondral support for maintenance of stability. The purpose of this article is to describe a volar transverse plate and screw technique and report the short-term postoperative results. Read More

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http://dx.doi.org/10.1177/1558944718790063DOI Listing
July 2018
4 Reads

Estimated Effectiveness and Safety of Nonvitamin K Antagonist Oral Anticoagulants Compared With Optimally Acenocoumarol Anticoagulated "Real-World" in Patients With Atrial Fibrillation.

Am J Cardiol 2018 Sep 2;122(5):785-792. Epub 2018 Jun 2.

Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, United Kingdom; Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.

Nonvitamin K antagonist oral anticoagulants (NOACs) have been proposed as an alternative to vitamin K antagonists in atrial fibrillation (AF) patients but the comparative benefits between NOACs and optimally anticoagulated patients is unknown. We estimated the absolute benefit in clinical outcomes rates of real-world effect of NOACs in optimally anticoagulated AF patients with acenocoumarol. We included 1,361 patients stable on acenocoumarol with time in therapeutic range of 100% and 6. Read More

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http://dx.doi.org/10.1016/j.amjcard.2018.05.012DOI Listing
September 2018
2 Reads

Glucolipotoxic conditions induce β-cell iron import, cytosolic ROS formation and apoptosis.

J Mol Endocrinol 2018 Aug;61(2):69-77

Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.

Type 2 diabetes (T2D) arises when the pancreatic beta-cell fails to compensate for increased insulin needs due to insulin resistance. Glucolipotoxicity (GLT) has been proposed to induce beta-cell dysfunction in T2D by formation of reactive oxygen species (ROS). Here, we examined if modeling glucolipotoxic conditions by high glucose-high free fatty acid (FFA) exposure (GLT) regulates beta-cell iron transport, by increasing the cytosolic labile iron pool (LIP). Read More

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http://dx.doi.org/10.1530/JME-17-0262DOI Listing
August 2018
3 Reads
3.081 Impact Factor

Post-surgical effects on the maxillary segments of children with oral clefts: New three-dimensional anthropometric analysis.

J Craniomaxillofac Surg 2018 Sep 30;46(9):1511-1514. Epub 2018 Jun 30.

Department of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, and Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, SP, Brazil. Electronic address:

This study aimed to use new three-dimensional (3D) anthropometric analyses to verify the post-surgical effects on the maxillary segments of children with unilateral cleft lip and palate. The sample was composed by digitized dental models of 60 children with unilateral complete cleft lip and alveolus (UCLA) and complete unilateral cleft lip and palate (UCLP). The impressions were taken before cheiloplasty (T1), after cheiloplasty (T2), and after palatoplasty (T3). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10105182183047
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http://dx.doi.org/10.1016/j.jcms.2018.06.017DOI Listing
September 2018
1 Read

A centralized automated-dispensing system in a French teaching hospital: return on investment and quality improvement.

Int J Qual Health Care 2018 Jul 11. Epub 2018 Jul 11.

Pharmacy Department, Hôpital Européen Georges Pompidou, APHP, 20 Rue Leblanc, Paris, France.

Objectives: To evaluate the return on investment (ROI) and quality improvement after implementation of a centralized automated-dispensing system after 8 years of use.

Design: Prospective evaluation of ROI; before and after study to evaluate dispensing errors; user satisfaction questionnaire after 8 years of use.

Setting: The study was conducted at a French teaching hospital in the pharmacy department, which is equipped with decentralized automated medication cabinets in the wards. Read More

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http://dx.doi.org/10.1093/intqhc/mzy152DOI Listing
July 2018
7 Reads

Lip repositioning with or without myotomy: A randomized clinical trial.

J Periodontol 2018 Jul;89(7):815-823

Department of Oral medicine and Periodontology, Faculty of Oral and Dental Medicine-Cairo University, Manial, Cairo, Egypt.

Background: Lip repositioning is a conservative surgical method for the correction of excess gingival display (EGD) by limiting the upward retraction of the lips. Lip repositioning presents a simple method for the treatment of gummy smile. The aim of this randomized clinical trial (RCT) was to assess lip repositioning, compared to lip repositioning with muscle severance for efficacy in treatment of EGD and resultant stability. Read More

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http://dx.doi.org/10.1002/JPER.17-0598DOI Listing

Nicotine-Induced Neuroprotection in Rotenone In Vivo and In Vitro Models of Parkinson's Disease: Evidences for the Involvement of the Labile Iron Pool Level as the Underlying Mechanism.

Neurotox Res 2018 Jul 13. Epub 2018 Jul 13.

Departamento de Neuroquímica, Instituto de Investigaciones Biológicas Clemente Estable, Avenida Italia 3318, CP: 11600, Montevideo, Uruguay.

Parkinson's disease (PD) is characterized by the degeneration of the dopaminergic neurons in the substantia nigra pars compacta (SNpc). Clinical and experimental evidence suggest that the activation of the nicotinic acetylcholine receptor (nAChR) could be protective for PD. In this study, we investigated the neuroprotective capacity of nicotine in a rat PD model. Read More

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http://dx.doi.org/10.1007/s12640-018-9931-1DOI Listing
July 2018
2 Reads

Correction of Eyes and Lip Canting after Bimaxillary Orthognathic Surgery.

Yonsei Med J 2018 Aug;59(6):793-797

Institute for Human Tissue Restoration, Department of Plastic & Reconstructive Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Patients who have a lower facial asymmetry with compensatory head posture (developmental facial asymmetry) may have minor temporomandibular (T-M) joint problems and tend to mask their asymmetry by tilting the head for camouflage of their chin deviation. However, this compensatory head posture can give the impression of orbital dystopia and c spine deviation. When these patients undergo bimaxillary orthognathic surgery, orbital canting and head tilting improves gradually without the need for camouflage, and bleary eyes become clearer. Read More

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http://dx.doi.org/10.3349/ymj.2018.59.6.793DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037602PMC
August 2018
8 Reads

Effects of force magnitude on torque control in the correction of bimaxillary protrusion with mass retraction.

J Orthod Sci 2018 6;7:13. Epub 2018 Jun 6.

Department of Orthodontics, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, China.

Objectives: This study was designed to explore whether force magnitude would influence incisor torque control and the overall outcome in patients with bimaxillary protrusion who need mass incisor retraction.

Materials And Methods: Forty-one female patients (aged > 15 years) with bimaxillary protrusion requiring mass incisor retraction were selected. Two sliding mechanics were utilized, with the elastic group receiving a light force of ~100 g by wearing elastics and the power chain group receiving a moderate force of ~250 g by power chain. Read More

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http://dx.doi.org/10.4103/jos.JOS_65_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004741PMC
June 2018
13 Reads

A Comparative Evaluation of Efficacy and Efficiency of Grayson's Presurgical Nasoalveolar Molding Technique in Patients with Complete Unilateral Cleft Lip and Palate with Those Treated with Figueroa's Modified Technique.

Contemp Clin Dent 2018 Jun;9(Suppl 1):S28-S33

Private Practioner, New Delhi, India.

Background: Presurgical nasoalveolar molding (PNAM) has been used for aligning and not only for approximating the maxillary alveolar segments preoperatively but also for improving the nasal symmetry and therefore facilitates primary surgical repairs in cleft patients.

Aim: This study was conducted to compare the efficacy and efficiency of Grayson's technique with Figueroa's modified presurgical nasoalveolar technique in complete unilateral cleft lip and palate (UCLP) infants.

Materials And Methods: Twenty-two infants aged 10-15 days were randomly divided into two equal groups: Group I treated with Grayson's PNAM technique and Group II with Figueroa's PNAM technique. Read More

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http://dx.doi.org/10.4103/ccd.ccd_820_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006901PMC
June 2018
1 Read

Total bleeding with rivaroxaban versus warfarin in patients with atrial fibrillation receiving antiplatelet therapy after percutaneous coronary intervention.

J Thromb Thrombolysis 2018 Oct;46(3):346-350

Division of Cardiovascular Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

Among atrial fibrillation (AF) patients undergoing percutaneous coronary intervention (PCI), rivaroxaban with background antiplatelet therapy significantly reduced the first occurrence of bleeding compared to triple therapy with warfarin. This study hypothesized that total bleeding events, including those beyond the first event, would be reduced with rivaroxaban-based regimens. In the PIONEER AF-PCI trial, 2099 patients in the modified intention-to-treat population were randomized to three groups and followed for 12 months: (1) rivaroxaban 15 mg once daily plus a P2Y inhibitor (N = 696); (2) rivaroxaban 2. Read More

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http://dx.doi.org/10.1007/s11239-018-1703-5DOI Listing
October 2018
21 Reads
2.039 Impact Factor

Lateral intraparietal area (LIP) is largely effector-specific in free-choice decisions.

Sci Rep 2018 Jun 5;8(1):8611. Epub 2018 Jun 5.

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.

Despite many years of intense research, there is no strong consensus about the role of the lateral intraparietal area (LIP) in decision making. One view of LIP function is that it guides spatial attention, providing a "saliency map" of the external world. If this were the case, it would contribute to target selection regardless of which action would be performed to implement the choice. Read More

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http://dx.doi.org/10.1038/s41598-018-26366-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988653PMC

Volumetric comparison of autogenous bone and tissue-engineered bone replacement materials in alveolar cleft repair: a systematic review and meta-analysis.

Br J Oral Maxillofac Surg 2018 07 30;56(6):453-462. Epub 2018 May 30.

Department of Oral and Maxillofacial Surgery, RWTH Aachen University, Aachen, Germany.

The goal of reconstruction of the alveolar cleft in patients with cleft lip and palate is to improve the quality of tissue, the structural stability, and increase the volume of bone. This study is a systematic review with meta-analysis of volumetric bony filling using autogenous bone and various tissue-engineered bone substitutes. We made an electronic search on MEDLINE, EMBASE, SCOPUS, WEB OF SCIENCE, "grey" publications (materials and research produced by organisations outside traditional channels for commercial or academic publishing and distribution), and relevant cross references according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Read More

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http://dx.doi.org/10.1016/j.bjoms.2018.05.007DOI Listing
July 2018
8 Reads

Could fetal reduction induce facial cleft? Report of a case.

Br J Oral Maxillofac Surg 2018 07 30;56(6):543-545. Epub 2018 May 30.

Department of Cranio-Maxillo-Facial Surgery of the Pediatric Hospital, Hôpital Femme Mère Enfant, 59 Boulevard Pinel, 69677 Bron, France; Université Claude Bernard Lyon 1, 43 Boulevard du 11 Novembre 1918, 69100 Villeurbanne; INSERM, National Institute of Health and Medical Research, Unit 1032, 151 Cours Albert Thomas, 69424 Lyon Cedex 03.

We describe a paramedian cleft of the lower lip that cannot be explained by embryological development in a child with only one predisposing factor, which was fetal reduction for a multiple pregnancy. To the best of our knowledge, there has been no report of a cleft that has been induced by the reduction of a multifetal pregnancy. Read More

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http://dx.doi.org/10.1016/j.bjoms.2018.05.009DOI Listing
July 2018
1 Read

Bromelain-based enzymatic debridement and minimal invasive modality (mim) care of deeply burned hands.

Ann Burns Fire Disasters 2017 Sep;30(3):198-204

Department of Plastic Surgery and Burn Unit, Soroka Medical Center, The Ben-Gurion University of the Negev, Beer Sheva, Israel.

The objective was to critically review the data and assess the implications of NexoBrid [NexoBrid-NXB formerly Debrase Gel Dressing-DGD] in the special field of deep hand burns. Detailed analysis of endpoints in the treatment of hand burn patients was conducted as part of a multi-center, open label, randomized, controlled two-arm study to evaluate the safety and efficacy of NXB enzymatic debridement, comparing it to the current standard of care (SOC). These results were compared to a large cohort of patients treated with NXB in a previous, single arm study. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946757PMC
September 2017
2 Reads

Increased burden of comorbidities and risk of cardiovascular death in atrial fibrillation patients in Europe over ten years: A comparison between EORP-AF pilot and EHS-AF registries.

Eur J Intern Med 2018 09 16;55:28-34. Epub 2018 May 16.

Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, United Kingdom; Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. Electronic address:

Background: In 2002, the European Society of Cardiology conducted the Euro Heart Survey (EHS), while in 2014concluded 1-year follow-up of the EURObservational Research Programme AF (EORP-AF) Pilot Registry.

Methods: We analysed differences in clinical profiles, therapeutic approaches and outcomes between these two cohorts after propensity score matching (PSM).

Results: After PSM, 5206 patients were analysed. Read More

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http://dx.doi.org/10.1016/j.ejim.2018.05.016DOI Listing
September 2018
6 Reads

Tensile Property of ANSI 304 Stainless Steel Weldments Subjected to Cavitation Erosion Based on Treatment of Laser Shock Processing.

Materials (Basel) 2018 May 16;11(5). Epub 2018 May 16.

School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.

Tensile property was one important index of mechanical properties of ANSI 304 stainless steel laser weldments subjected to cavitation erosion (CE). Laser shock processing (LSP) was utilized to strengthen the CE resistance, and the tensile property and fracture morphology were analyzed through three replicated experiment times. Results showed tensile process of treated weldments was composed of elastic deformation, plastic deformation, and fracture. Read More

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http://www.mdpi.com/1996-1944/11/5/805
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http://dx.doi.org/10.3390/ma11050805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978182PMC
May 2018
2 Reads

A Standardized Protocol for the Prospective Follow-Up of Cleft Lip and Palate Patients.

Cleft Palate Craniofac J 2018 Jan 1:1055665618771422. Epub 2018 Jan 1.

3 British Columbia's Children's Hospital Cleft and Craniofacial Team, Vancouver, British Columbia, Canada.

Objective: To develop a standardized all-encompassing protocol for the assessment of cleft lip and palate patients with clinical and research implications.

Method: Electronic database searches were conducted and 13 major cleft centers worldwide were contacted in order to prepare for the development of the protocol. In preparation, the available evidence was reviewed and potential fistula-related risk determinants from 4 different domains were identified. Read More

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http://journals.sagepub.com/doi/10.1177/1055665618771422
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http://dx.doi.org/10.1177/1055665618771422DOI Listing
January 2018
6 Reads

Metabolic and Structural Imaging at 7 Tesla After Repetitive Mild Traumatic Brain Injury in Immature Rats.

ASN Neuro 2018 Jan-Dec;10:1759091418770543

1 Safar Center for Resuscitation Research, Department of Critical Care Medicine, University of Pittsburgh, PA, USA.

Mild traumatic brain injury (mTBI) in children is a common and serious public health problem. Traditional neuroimaging findings in children who sustain mTBI are often normal, putting them at risk for repeated mTBI (rmTBI). There is a need for more sensitive imaging techniques capable of detecting subtle neurophysiological alterations after injury. Read More

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http://journals.sagepub.com/doi/10.1177/1759091418770543
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http://dx.doi.org/10.1177/1759091418770543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944144PMC
May 2018
4 Reads

Wooden Spatula for Pain Reduction in Upper Lip Laser Hair Removal.

J Cutan Aesthet Surg 2018 Jan-Mar;11(1):38-39

Department of Dermatology, Venereology and Leprosy, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India.

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http://dx.doi.org/10.4103/JCAS.JCAS_8_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921449PMC
May 2018
1 Read