1,614 results match your criteria Lip Reduction


State Medicaid expansion status, insurance coverage and stage at diagnosis in head and neck cancer patients.

Oral Oncol 2020 Jul 3;110:104870. Epub 2020 Jul 3.

Harvard Medical School, Massachusetts Eye and Ear Infirmary, Department of Otolaryngology, Boston, MA, USA.

Objectives: Only one in three head and neck cancer (HNC) patients present with early-stage disease. We aimed to quantify associations between state Medicaid expansions and changes in insurance coverage rates and stage at diagnosis of HNC.

Methods: Using a quasi-experimental difference-in-differences (DID) approach and data from 26,330 cases included in the Surveillance, Epidemiology, and End Results program (2011-2015), we retrospectively examined changes in insurance coverage and stage at diagnosis of adult HNC in states that expanded Medicaid (EXP) versus those that did not (NEXP). Read More

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http://dx.doi.org/10.1016/j.oraloncology.2020.104870DOI Listing

Major birth defects in the Brazilian side of the triple border: a population-based cross-sectional study.

Arch Public Health 2020 30;78:61. Epub 2020 Jun 30.

Latin-American Institute of Life and Natural Sciences, Federal University of Latin-American Integration, Foz do Iguassu, Parana Brazil.

Background: Major birth defects increase the risk of fetal death and pediatric hospitalization, which also impact on healthcare costs. Sociodemographic factors can drastically affect reproductive health and be used to discriminate the exposure to hidden risk factors. Foz do Iguassu is a Brazilian city located in the triple-border region of Brazil / Paraguay / Argentina with high rates of birth defects. Read More

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http://dx.doi.org/10.1186/s13690-020-00443-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325680PMC

Integrated propranolol, methylprednisolone, and surgery in managing a rare case of infantile hemangioma with concurrent cleft lip and palate.

Ann Med Surg (Lond) 2020 Aug 19;56:91-94. Epub 2020 Jun 19.

Plastic, Reconstructive, and Aesthetic Surgery Division, Department of Surgery, Faculty of Medicine, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, 55281, Indonesia.

Infantile hemangioma (IH) with concurrent cleft lip and palate is a rare case. Surgical management is often considered as the best management for infantile hemangioma with concurrent cleft lip and palate. However, considering the functionality aspect and aesthetic appearance, a plastic surgeon can also consider non-surgical management without interrupting the surgical timeline for the cleft lip and palate. Read More

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http://dx.doi.org/10.1016/j.amsu.2020.06.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322350PMC

Influence of Parental Exposure to Risk Factors in the Occurrence of Oral Clefts.

J Dent (Shiraz) 2020 Jun;21(2):119-126

Dept. of Pediatric Dentistry, Dental School, University of Cuiabá, Cuiabá, Brazil.

Statement Of The Problem: Non-syndromic cleft lip and palate are the most frequent craniofacial abnormalities in humans. The genetic, environmental and behavioral factors involved in this malformation must be clarified in different parts of the globe in the view of implementing preventive measures.

Purpose: To analyze the influence of parental exposure to risk factors on the occurrence of oral clefts. Read More

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http://dx.doi.org/10.30476/DENTJODS.2019.77620.0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280550PMC

Dabigatran Dual Therapy vs Warfarin Triple Therapy Post-Percutaneous Coronary Intervention in Patients with Atrial Fibrillation With/Without a Proton Pump Inhibitor: A Pre-Specified Analysis of the RE-DUAL PCI Trial.

Drugs 2020 Jul;80(10):995-1005

Brigham and Women's Hospital and Heart and Vascular Center, and Harvard Medical School, Boston, MA, USA.

Background And Objective: In patients with atrial fibrillation following percutaneous coronary intervention, if a proton pump inhibitor is used, could that allow the use of warfarin triple therapy, or is there additional reduction in bleeding while using it with dual therapy?

Methods: The RE-DUAL PCI trial randomized 2725 patients with atrial fibrillation post-percutaneous coronary intervention to dabigatran dual therapy (110 or 150 mg twice daily, with clopidogrel or ticagrelor) or warfarin triple therapy (with clopidogrel or ticagrelor, and aspirin for 1-3 months). This prespecified subgroup analysis evaluated risks of a first major bleeding event or clinically relevant non-major bleeding event, all gastrointestinal bleeding, and a composite efficacy endpoint of all-cause mortality/thromboembolic event or unplanned revascularization according to baseline use of a proton pump inhibitor.

Results: Of 2678 analyzed patients, 1641 (61. Read More

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http://dx.doi.org/10.1007/s40265-020-01323-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320045PMC

Does playing a wind instrument influence tooth position and facial morphology? : Systematic review and meta-analysis.

J Orofac Orthop 2020 Jul 7;81(4):267-285. Epub 2020 May 7.

Department of Periodontology, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

Purpose: To systematically search the scientific literature concerning the influence of playing a wind instrument on tooth position and/or facial morphology.

Methods: The PubMed, EMBASE and Cochrane databases were searched up to September 2019. Orthodontic journals were hand searched and grey literature was sought via Google Scholar. Read More

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http://dx.doi.org/10.1007/s00056-020-00223-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316676PMC

The First-Year Follow-Up of a Cleft Lip and Palate Patient Treated With Nasoalveolar Molding (NAM).

Braz Dent J 2020 Jan-Apr;31(2):190-196

Department of Restorative Dentistry, Faculty of Dentistry, UFMG - Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.

The objectives of pre-surgical orthopedics are to allow surgical repair with minimal tension of the involved tissues and less restriction to the craniofacial growth. The aim of this study was to evaluate the benefits of nasoalveolar model (NAM) as a pre-operative therapy in a patient with bilateral cleft lip and palate followed by labioplasty and palatoplasty. A 15-day-old patient underwent orthopedic treatment with NAM. Read More

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http://dx.doi.org/10.1590/0103-6440202003040DOI Listing

Impact of atrial fibrillation in critically ill patients admitted to a stepdown unit.

Eur J Clin Invest 2020 Jun 14:e13317. Epub 2020 Jun 14.

Department of Biomedical Sciences and Public Health, Cardiology and Arrhythmology Clinic, Marche Polytechnic University, A.O.U. "Ospedali Riuniti", Ancona, Italy.

Background: Limited data are available on the clinical course of patients with history of atrial fibrillation (AF) when admitted in an intensive care environment. We aimed to describe the occurrence of major adverse events in AF patients admitted to a stepdown care unit (SDU) and to analyse clinical factors associated with outcomes, impact of dicumarolic oral anticoagulant (OAC) therapy impact and performance of clinical risk scores in this setting.

Materials And Methods: Single-centre, observational retrospective analysis on a population of subjects with AF history admitted to a SDU. Read More

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http://dx.doi.org/10.1111/eci.13317DOI Listing

Volar Scaphoid Plating for Nonunion: A Multicenter Case Series Study.

J Wrist Surg 2020 Jun 6;9(3):225-229. Epub 2020 Mar 6.

Department of Orthopaedic Surgery, Barwon Health, Geelong, Australia.

 The volar scaphoid plate from Medartis (Medartis AG, Austrasse, Basel, Switzerland) is a variable angle titanium locking plate, preformed for the volar aspect of the scaphoid. It does not have compressive capability, and may act as a bridging device. It may provide an advantage over a compression screw where the pathoanatomy is less favorable to such a device with increased rotational stability. Read More

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http://dx.doi.org/10.1055/s-0040-1702199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263855PMC

Evaluation of the Nasopharyngeal Cannula Use After Orthognathic Surgery: Permeability of the Nasal Airways and Discomfort of the Patient With Cleft Lip and Palate.

J Craniofac Surg 2020 Jun 4. Epub 2020 Jun 4.

Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo (HRAC-USP).

It is believed that the use of the nasopharyngeal cannula can maintain the patent upper airway in the immediate post-operative period of orthognathic surgery. The present study is a randomized clinical trial with the objective of evaluating the difference in the use of the nasopharyngeal cannula in the post-operative period of orthognathic surgery with respect to permeability and discomfort. The sample was composed of 26 individuals with repaired cleft lip and palate randomly distributed in 2 groups with and without nasopharyngeal cannula. Read More

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http://dx.doi.org/10.1097/SCS.0000000000006605DOI Listing

Genetic variants in S-adenosyl-methionine synthesis pathway and nonsyndromic cleft lip with or without cleft palate in Chile.

Pediatr Res 2020 Jun 3. Epub 2020 Jun 3.

Institute for Research in Dental Sciences, School of Dentistry, Universidad de Chile, Santiago, Chile.

Background: The S-adenosyl-methionine (SAM) availability is crucial for DNA methylation, an epigenetic mechanism involved in nonsyndromic cleft lip with or without cleft palate (NSCL/P) expression. The aim of this study was to assess the association between single-nucleotide polymorphisms (SNPs) of genes involved in SAM synthesis and NSCL/P in a Chilean population.

Methods: In 234 cases and 309 controls, 18 SNPs in AHCY, MTR, MTRR, and MAT2A were genotyped, and the association between them and the phenotype was evaluated based on additive (allele), dominant, recessive and haplotype models, by odds ratio (OR) computing. Read More

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http://dx.doi.org/10.1038/s41390-020-0994-3DOI Listing

A Modified 2-Stage Treatment for AO/OTA 43-C1 Pilon Fractures Accompanied by Distal Fibular and Posterior Lip of the Distal Tibia Fracture.

J Foot Ankle Surg 2020 May 29. Epub 2020 May 29.

Associate Registrar, Department of Orthopaedics, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China. Electronic address:

The management of pilon fractures remains challenging owing to the high-energy axial loading mechanism that produces comminution of the articular surface, displacement of tibia metaphysis, and severe soft tissue injury. How to preserve the vitality of soft tissue and achieve anatomic reduction has become a timely issue. We report and evaluate the effect of a modified staging treatment for AO Foundation/Orthopaedic Trauma Association (AO/OTA) 43C1 pilon fracture accompanied by distal fibular and posterior lip of the distal tibia fracture. Read More

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http://dx.doi.org/10.1053/j.jfas.2020.03.020DOI Listing

Prospective evaluation of the effect of early nasal layer closure on definitive repair in cleft palate patients.

Braz J Otorhinolaryngol 2020 May 5. Epub 2020 May 5.

University of Kufa, College of Medicine, Department of Surgery, Najaf, Iraq.

Introduction: The cleft palate is one of the most common congenital anomalies treated by plastic surgeons. The cleft width increases the tension of repair and necessitates excessive dissection that might affect maxillary growth. Decreasing the width of cleft minimize tension, dissection and may limit the impact on maxillary growth. Read More

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http://dx.doi.org/10.1016/j.bjorl.2020.04.003DOI Listing

Bilateral, buccinator myomucosal advancement flaps to reconstruct central upper labial myomucosal defects after ablation of early-stage cancer in minor salivary glands.

J Cosmet Dermatol 2020 May 28. Epub 2020 May 28.

Department of Pathology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.

Background: Reconstruction of upper labial myomucosal defects is surgically challenging.

Aims: We evaluated whether central defects could be repaired using bilateral, buccinator myomucosal advancement flaps (b-BMAFs).

Methods: We evaluated five patients with early-stage, minor salivary gland mucoepidermoid carcinomas (low-grade [n = 2], intermediate-grade [n = 2], and high-grade [n = 1]) who underwent central, upper labial myomucosal reconstruction using b-BMAFs after cancer ablation. Read More

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http://dx.doi.org/10.1111/jocd.13513DOI Listing

Management of intraarticular proximal interphalangeal joint fracture-dislocations and pilon fractures with the Ligamentotaxor® device.

Arch Orthop Trauma Surg 2020 May 25. Epub 2020 May 25.

St Andrews Centre for Plastic Surgery, Broomfield Hospital, Chelmsford, CM1 7ET, UK.

Introduction: Fracture-dislocation and pilon injuries of the proximal interphalangeal joints (PIPJ) continue to pose significant management challenges. Stable fracture configurations can be treated with extension block splinting or pinning. Unstable fractures usually require open or closed reduction and fixation either directly/internally onto the fracture using Kirschner wires, cerclage wires, screws or miniplates or indirectly/externally by ligamentotaxis using external fixators which can be dynamic or static. Read More

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http://dx.doi.org/10.1007/s00402-020-03482-8DOI Listing

Arginine vasotocin impacts chemosensory behavior during social interactions of Anolis carolinensis lizards.

Horm Behav 2020 May 26;124:104772. Epub 2020 May 26.

Georgia State University, Neuroscience Institute and Center for Behavioral Neuroscience, Atlanta, GA, USA.

In reptiles, arginine vasotocin (AVT) impacts the performance of and response to visual social signals, but whether AVT also operates within the chemosensory system as arginine vasopressin (AVP) does in mammals is unknown, despite social odors being potent modifiers of competitive and appetitive behavior in reptiles. Here, we ask whether elevated levels of exogenous AVT impact rates of chemical display behavior (e.g. Read More

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http://dx.doi.org/10.1016/j.yhbeh.2020.104772DOI Listing

Effectiveness, safety, and major adverse limb events in atrial fibrillation patients with concomitant diabetes mellitus treated with non-vitamin K antagonist oral anticoagulants.

Cardiovasc Diabetol 2020 May 13;19(1):63. Epub 2020 May 13.

Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, UK.

Background: Evidence of adverse clinical outcomes for non-vitamin K antagonist oral anticoagulant (NOACs) and warfarin in patients with atrial fibrillation (AF) and diabetes mellitus are limited. We investigated the effectiveness, safety, and major adverse limb events for NOACs versus warfarin among diabetic AF patients.

Methods: In this nationwide retrospective cohort study collected from Taiwan National Health Insurance Research Database, we identified a total of 20,967 and 5812 consecutive AF patients with diabetes taking NOACs and warfarin from June 1, 2012, to December 31, 2017, respectively. Read More

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http://dx.doi.org/10.1186/s12933-020-01043-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222472PMC

Advanced biological sequential treatment of mature landfill leachate using aerobic activated sludge SBR and fungal bioreactor.

J Environ Health Sci Eng 2020 Jun 16;18(1):285-295. Epub 2020 Mar 16.

Department of Civil Engineering, University of Manitoba, Winnipeg, MB R3T 5V6 Canada.

This study utilized spp. to treat mature landfill leachate (MLL) in a continuous bioreactor and batch experimental tests under non-sterile conditions. MLL characteristics such as chemical oxygen demand (COD), soluble COD (sCOD), total carbon (TC), total organic carbon (TOC), and color removal efficiency were determined. Read More

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http://dx.doi.org/10.1007/s40201-020-00466-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203322PMC

Comparison of Dabigatran Plus a P2Y Inhibitor with Warfarin-Based Triple Therapy across Body Mass Index in RE-DUAL PCI.

Am J Med 2020 May 7. Epub 2020 May 7.

Brigham and Women's Hospital, Heart and Vascular Center, Boston and Harvard Medical School, Boston, MA;. Electronic address:

Background: Body mass index (BMI) affects drug levels of nonvitamin K antagonist oral anticoagulants. We sought to assess whether BMI affected outcomes in the RE-DUAL PCI trial.

Methods: RE-DUAL PCI (NCT02164864) evaluated the safety and efficacy of a dual antithrombotic therapy regimen using dabigatran (110 or 150 mg twice daily [BID] and a P2Y platelet antagonist), in comparison with "triple therapy" with warfarin, aspirin, and a P2Y platelet inhibitor, in 2725 patients with atrial fibrillation who had undergone percutaneous coronary intervention (PCI). Read More

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http://dx.doi.org/10.1016/j.amjmed.2020.03.045DOI Listing

Enzymatic and genetic characterization of lignin depolymerization by Streptomyces sp. S6 isolated from a tropical environment.

Sci Rep 2020 May 8;10(1):7813. Epub 2020 May 8.

Department of Chemical Process Engineering, Malaysia-Japan International Institute of Technology, Universiti Teknologi Malaysia, Jalan Sultan Yahya Petra, 54100, Kuala Lumpur, Malaysia.

The conversion of lignocellulosic biomass into bioethanol or biochemical products requires a crucial pretreatment process to breakdown the recalcitrant lignin structure. This research focuses on the isolation and characterization of a lignin-degrading bacterial strain from a decaying oil palm empty fruit bunch (OPEFB). The isolated strain, identified as Streptomyces sp. Read More

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http://dx.doi.org/10.1038/s41598-020-64817-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210275PMC

Balancing the dental occlusion and facial aesthetic features in cleft orthognathic surgery: Patient-centered concept for computer-aided planning.

Biomed J 2020 Apr 4;43(2):143-145. Epub 2020 May 4.

Department of Plastic and Reconstructive Surgery and Craniofacial Research Center, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan. Electronic address:

Patients with cleft lip and palate could develop dentofacial deformity characterized by malocclusion, midface retrusion, midline discrepancy and asymmetry. Cleft orthognathic surgery has evolved from the simple maxillary LeFort I advancement with correction of dental malocclusion to the current model of patient-centered approach focusing on skeletofacial reconstruction using computer-assisted diagnosis and planning. Three-dimensional imaging and surgical simulation have provided valuable information for facial aesthetics and surgical feasibility. Read More

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http://dx.doi.org/10.1016/j.bj.2019.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283565PMC

Comprehensive Management With the ABC (Atrial Fibrillation Better Care) Pathway in Clinically Complex Patients With Atrial Fibrillation: A Post Hoc Ancillary Analysis From the AFFIRM Trial.

J Am Heart Assoc 2020 May 6;9(10):e014932. Epub 2020 May 6.

Liverpool Centre for Cardiovascular Science University of Liverpool and Liverpool Heart & Chest Hospital Liverpool United Kingdom.

Background For patients with atrial fibrillation, a comprehensive care approach based on the Atrial fibrillation Better Care (ABC) pathway can reduce the occurrence of adverse outcomes. The aim of this paper was to investigate if an approach based on the ABC pathway is associated with a reduced risk of adverse events in "clinically complex" atrial fibrillation patients, including those with multiple comorbidities, polypharmacy, and prior hospitalizations. Methods and Results We performed a post hoc analysis of the AFFIRM (Atrial Fibrillation Follow-up Investigation of Rhythm Management) trial. Read More

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http://dx.doi.org/10.1161/JAHA.119.014932DOI Listing

The role of macrophages in osseointegration of dental implants: An experimental study in vivo.

J Biomed Mater Res A 2020 May 3. Epub 2020 May 3.

State Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases & Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture, Department of Oral Implants, School of Stomatology, The Fourth Military Medical University, China.

To investigate the role of macrophages in the osseointegration of dental implants through induced macrophage reduction in a murine model. Fifty-four Sprague-Dawley rats with bilateral maxillary first molars replaced by titanium implants were randomly assigned into three groups. For the test group, macrophages were depleted by tail-vein injection of clodronate liposome (20 mg/kg) 3 days before implantation and reinjection every 3 days until the sacrifice of the rats (10 mg/kg). Read More

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http://dx.doi.org/10.1002/jbm.a.36978DOI Listing

101 Amyotrophic Lateral Sclerosis (ALS) - Not Just a Motor Disease? Isolated Bitter and Sweet Taste Loss in ALS.

CNS Spectr 2020 Apr;25(2):266

Smell and Taste Treatment and Research Foundation, Chicago, Illinois.

Study Objective: Specific taste quality deficits in ALS has not heretofore been described.

Method: Case Study: A 71 year old right handed female presented with a two year course of progressive reduction in strength in her hands, arms and legs with difficulty tying shoe laces, opening jars, writing and walking. She described nocturnal muscle spasms involving all extremities. Read More

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http://dx.doi.org/10.1017/S109285292000019XDOI Listing

A single-center blinded randomized clinical trial to evaluate the anti-aging effects of a novel HSF™-based skin care formulation.

J Cosmet Dermatol 2020 Apr 19. Epub 2020 Apr 19.

College of Pharmacy, University of Florida, Gainesville, FL, USA.

Background: Similar to chronic wounds, skin aging is characterized by dysfunction of key cellular regulatory pathways. The hypoxia-inducible factor-1 alpha (HIF-1α) pathway was linked to both conditions. Recent evidence suggests that modulating this pathway can rejuvenate aged fibroblasts and improve skin regeneration. Read More

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http://dx.doi.org/10.1111/jocd.13356DOI Listing

Evaluation of Lower Dental Arch Crowding and Dimension after Treatment with Lip Bumper versus Schwarz Appliance. A Prospective Pilot Study.

Dent J (Basel) 2020 Apr 10;8(2). Epub 2020 Apr 10.

Department of Health, Life and Environmental Science, University of L'Aquila, Piazza Salvatore Tommasi, 67100 L'Aquila, Italy.

The treatment of patients with mixed dentition, with inferior moderate dental crowding (the so-called borderline cases, between extraction and expansion) is not yet clear. Two examples of widely used appliances for increasing lower dental arch dimensions are the Schwarz's appliance and lip bumper. The aim of this prospective study was to compare dental crowding and arch dimensions from pre- to post-treatment with lip bumper versus Schwarz's appliance. Read More

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http://dx.doi.org/10.3390/dj8020034DOI Listing

Regular Bleeding Risk Assessment Associated with Reduction in Bleeding Outcomes: The mAFA-II Randomized Trial.

Am J Med 2020 Apr 12. Epub 2020 Apr 12.

Medical School of Chinese PLA, Department of Cardiology, Chinese PLA General Hospital, Beijing, China; Liverpool Centre for Cardiovascular Sciences, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, United Kingdom; Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. Electronic address:

Background: The mobile atrial fibrillation application (mAFA-II) randomized trial reported that a holistic management strategy supported by mobile health reduced atrial fibrillation-related adverse outcomes. The present study aimed to assess whether regular reassessment of bleeding risk using the Hypertension, Abnormal renal and liver function, Stroke, Bleeding, Labile international normalized ratio, Elderly, Drugs or alcohol (HAS-BLED) score would improve bleeding outcomes and oral anticoagulant (OAC) uptake.

Methods: Bleeding risk (HAS-BLED score) was monitored prospectively using mAFA, and calculated as 30 days, days 31-60, days 61-180, and days 181-365. Read More

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http://dx.doi.org/10.1016/j.amjmed.2020.03.019DOI Listing

Simultaneous surgery of mandibular reduction and impacted mandibular third molar extraction: A retrospective study of 65 cases.

Medicine (Baltimore) 2020 Apr;99(15):e19397

The 16 Department, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing.

A considerable number of patients with prominent mandibular angle have mandibular third molar impaction that needs surgical removal. Mandibular reduction is a popular and effective surgery to correct prominent mandibular angle, but it has been rarely performed simultaneously with impacted third molar extraction. In order to decrease the number of operations and suffering of patients, safely performing these 2 operations together is necessary and important. Read More

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http://dx.doi.org/10.1097/MD.0000000000019397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220061PMC

Applied Online Crowdsourcing in Plastic and Reconstructive Surgery: A Comparison of Aesthetic Outcomes in Unilateral Cleft Lip Repair Techniques.

Ann Plast Surg 2020 May;84(5S Suppl 4):S307-S310

Division of Plastic and Reconstructive Surgery, Stanford University, Palo Alto, CA.

Background: Aesthetic outcomes of unilateral cleft lip repairs have important psychosocial implications for patients who are heavily influenced by social perceptions. Online crowdsourcing offers the unique potential to efficiently recruit large numbers of laypeople to assess public perception. The aim of this study was to use the online crowdsourcing platform Mechanical Turk to compare the postoperative outcomes of Fisher, Millard, and Mohler cleft lip repair techniques. Read More

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http://dx.doi.org/10.1097/SAP.0000000000002389DOI Listing

Skin surface lipid composition in women: increased 2,3-oxidosqualene correlates with older age.

Eur J Dermatol 2020 Apr 10. Epub 2020 Apr 10.

"Lipides: Systèmes Analytiques et Biologiques" Lip(Sys)2 interdisciplinary unit, Faculty of Pharmacy, University of Paris-Sud, Châtenay-Malabry 92290.

The importance of the hydrolipidic film of skin has been well documented, however, few data are available in cases of very old age. Our aim was to characterize the difference in skin surface lipid (SSL) composition between individuals of different age groups. Data were collected from the forehead of 22 young volunteers (18-24 years old) and 18 senior volunteers (70-75 years old). Read More

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http://dx.doi.org/10.1684/ejd.2020.3753DOI Listing

Lifestyle and risk factor modification for reduction of atrial fibrillation: We could do more.

Trends Cardiovasc Med 2020 Apr 8. Epub 2020 Apr 8.

Liverpool Centre for Cardiovascular Sciences, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, United Kingdom; Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.

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http://dx.doi.org/10.1016/j.tcm.2020.03.007DOI Listing

Combination Therapy for Macular Oedema in Retinal Vein Occlusions: 3-Year Results from a Real-World Clinical Practice.

Clin Ophthalmol 2020 27;14:955-965. Epub 2020 Mar 27.

Birmingham and Midland Eye Centre, Sandwell & West Birmingham NHS Trust, Birmingham B18 7QH, UK.

Purpose: To report long-term efficacy and treatment outcomes of the combination therapy for treating macular oedema (MO) in retinal vein occlusions (RVOs) from a real-world UK practice.

Methods: The initial reported 66 RVO patients with MO treated with combination therapy (initial Ranibizumab, later optional addition of Ozurdex and laser) were followed up to Year 3: visual acuity (VA) and central retinal thickness (CRT) were analysed against baseline and previous Year 1 results. Safety and adverse events were also recorded. Read More

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http://dx.doi.org/10.2147/OPTH.S241044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108880PMC

Effect of portable non-invasive ventilation on exercise tolerance in COPD: One size does not fit all.

Respir Physiol Neurobiol 2020 Jun 5;277:103436. Epub 2020 Apr 5.

Department of Sport, Exercise and Rehabilitation, Northumbria University Newcastle, Newcastle Upon-Tyne NE1 8ST, UK.

In a cross-over RCT, portable NIV (pNIV) reduced dynamic hyperinflation (DH) compared to pursed lip breathing (PLB) during recovery from intermittent exercise in COPD, but not consistently in all subjects. In this post-hoc analysis, DH response was defined as a reduction ≥4.5 % of predicted resting inspiratory capacity with pNIV compared to PLB. Read More

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http://dx.doi.org/10.1016/j.resp.2020.103436DOI Listing

Changes in maximum lip-closing force after extraction and nonextraction orthodontic treatments.

Korean J Orthod 2020 Mar 24;50(2):120-128. Epub 2020 Mar 24.

Department of Orthodontics, Seoul National University Bundang Hospital, Section of Dentistry, Seoul National University, Seongnam, Korea.

Objective: The aims of the present study were to evaluate the changes in the maximum lip-closing force (MLF) after orthodontic treatment with or without premolar extractions and verify the correlation of these changes with dentoskeletal changes.

Methods: In total, 17 women who underwent nonextraction orthodontic treatment and 15 women who underwent orthodontic treatment with extraction of all four first premolars were included in this retrospective study. For all patients, lateral cephalograms and dental models were measured before (T0) and after (T1) treatment. Read More

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http://dx.doi.org/10.4041/kjod.2020.50.2.120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093664PMC

Clinical outcomes associated with kidney function changes in anticoagulated atrial fibrillation patients: An ancillary analysis from the BOREALIS trial.

J Arrhythm 2020 Apr 6;36(2):282-288. Epub 2020 Feb 6.

Liverpool Centre for Cardiovascular Science University of Liverpool and Liverpool Heart & Chest Hospital Liverpool United Kingdom.

Background: Patients with atrial fibrillation (AF) and chronic kidney disease represent a high-risk group for thromboembolism and bleeding.

Aims: To explore the relationship between kidney function changes and outcomes of stroke/systemic embolism (SE), major bleeding and all-cause death in anticoagulated AF patients participating in the BOREALIS trial comparing efficacy and safety of once-weekly s.c. Read More

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http://dx.doi.org/10.1002/joa3.12306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132193PMC

Fungal treatment of mature landfill leachate utilizing woodchips and wheat-straw as co-substrates.

Biodegradation 2020 Apr 5;31(1-2):109-122. Epub 2020 Apr 5.

Department of Civil Engineering, University of Manitoba, Winnipeg, MB, R3T 5V6, Canada.

Mature landfill leachate (MLL) tend to be highly contaminated due to the presence of refractory contaminants such as humic-fulvic substances, xenobiotic compounds, and heavy metals. This study investigated the treatment efficiency of MLL by deploying Cladosporium sp., Trichoderma asperellum, and Tyromyces chioneus fungal strains. Read More

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http://dx.doi.org/10.1007/s10532-020-09897-9DOI Listing

Mobile Health Technology to Improve Care for Patients With Atrial Fibrillation.

J Am Coll Cardiol 2020 Apr;75(13):1523-1534

Medical School of Chinese PLA, Department of Cardiology, Chinese PLA General Hospital, Beijing, China; Liverpool Centre for Cardiovascular Sciences, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, United Kingdom, and Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. Electronic address:

Background: Current management of patients with atrial fibrillation (AF) is limited by low detection of AF, non-adherence to guidelines, and lack of consideration of patients' preferences, thus highlighting the need for a more holistic and integrated approach to AF management.

Objective: The objective of this study was to determine whether a mobile health (mHealth) technology-supported AF integrated management strategy would reduce AF-related adverse events, compared with usual care.

Methods: This is a cluster randomized trial of patients with AF older than 18 years of age who were enrolled in 40 cities in China. Read More

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http://dx.doi.org/10.1016/j.jacc.2020.01.052DOI Listing
April 2020
16.503 Impact Factor

Invagination of elevated lip liner preventing reduction of dislocated total hip.

Arthroplast Today 2020 Mar 7;6(1):14-17. Epub 2020 Jan 7.

Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, CA, USA.

Instability is the most common indication for revision total hip arthroplasty in the United States. Elevated-rim acetabular liners were introduced to minimize the risk of posterior instability. We describe a patient with multiple total hip arthroplasty dislocations secondary to component subsidence leading to instability. Read More

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http://dx.doi.org/10.1016/j.artd.2019.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083719PMC

Epidemiology of head and neck cancers: an update.

Authors:
Anne Aupérin

Curr Opin Oncol 2020 May;32(3):178-186

Biostatistic and Epidemiology Unit, Gustave Roussy, Oncostat INSERM 1018-CESP, 114 rue Edouard Vaillant, Villejuif, France.

Purpose Of Review: This review attempts to give an update of epidemiological knowledge on head and neck cancers (HNC).

Recent Findings: Worldwide, from 1990 to 2017, incidence rates for larynx and nasopharyngeal cancers decreased, whereas they increased for oro/hypopharyngeal cancers and lip/oral cavity cancers. They are still markedly higher among men than women. Read More

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http://dx.doi.org/10.1097/CCO.0000000000000629DOI Listing

Three-dimensional development of the palate in bilateral orofacial cleft newborns 1 year after early neonatal cheiloplasty: Classic and geometric morphometric evaluation.

J Craniomaxillofac Surg 2020 Apr 3;48(4):383-390. Epub 2020 Mar 3.

Department of Anthropology and Human Genetics, Faculty of Science, Charles University, Viničná 7, 128 43, Prague 2, Czech Republic.

Objectives: The aim of this study was to assess palatal growth in newborns with complete bilateral cleft lip and palate (cBCLP) and bilateral cleft lip and palate with tissue bridges (BCLP + B) 1 year after early neonatal cheiloplasty (ENC).

Material And Methods: The methodology was based on classic and morphometric analysis of dental models of newborns with cBCLP or BCLP + B. These analyses included metric analysis, coherent point drift-dense correspondence analysis, superprojection methods, and multivariate statistics. Read More

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http://dx.doi.org/10.1016/j.jcms.2020.02.019DOI Listing

Third Body Wear of UHMWPE-on-PEEK-OPTIMA™.

Materials (Basel) 2020 Mar 11;13(6). Epub 2020 Mar 11.

Institute of Medical and Biological Engineering, School of Mechanical Engineering, University of Leeds, Leeds LS2 9JT, UK.

PEEK-OPTIMA™ is being considered as an alternative to cobalt chrome (CoCr) in the femoral component of total knee replacements. To date, investigations of ultra-high molecular weight polyethylene (UHMWPE)-on-PEEK have shown an equivalent wear rate to conventional implant materials under standard conditions. In this study, the third body wear performance of UHMWPE-on-PEEK was directly compared to UHMWPE-on-CoCr in a series of pin-on-plate studies using two approaches for third body damage. Read More

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http://dx.doi.org/10.3390/ma13061264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142899PMC

Effects of a naturalistic intervention on the speech outcomes of young children with cleft palate.

Int J Speech Lang Pathol 2020 Mar 12:1-11. Epub 2020 Mar 12.

School of Communication, Northwestern University, Evanston, IL, USA.

: The purpose of this study was to investigate the extent to which a naturalistic communication intervention, Enhanced Milieu Teaching with Phonological Emphasis (EMT + PE) improved the speech outcomes of toddlers with cleft palate with or without cleft lip (CP ± L): This study was a stratified randomised controlled trial.Setting: Treatment was delivered in a university clinic by a trained speech-language pathologist.: Thirty children aged between 15 and 36 months ( = 25) with nonsyndromic CP ± CL and typical cognitive development were randomly assigned to a treatment (EMT + PE) or business as usual comparison condition. Read More

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http://dx.doi.org/10.1080/17549507.2019.1702719DOI Listing

Impact of Liver Disease on Oral Anticoagulant Prescription and Major Adverse Events in Patients with Atrial Fibrillation.

Eur Heart J Cardiovasc Pharmacother 2020 Mar 4. Epub 2020 Mar 4.

Department of Cardiovascular Medicine, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.

Aims: Data on the impact of liver disease (LD) in patients with atrial fibrillation (AF) and the role of oral anticoagulant (OAC) drugs for stroke prevention, are limited.

Methods: A retrospective observational population-based cohort study on the administrative health databases of Lombardy region Italy. All AF patients ≥40 years admitted to hospital from 2000 to 2018 were considered. Read More

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http://dx.doi.org/10.1093/ehjcvp/pvaa015DOI Listing

Assessment of Treatment Outcome of Presurgical Nasoalveolar Molding in Patients With Cleft Lip and Palate and Its Postsurgical Stability.

Cleft Palate Craniofac J 2020 Jun 1;57(6):700-706. Epub 2020 Mar 1.

Department of Orthodontics and Dentofacial Orthopedics, Maulana Azad Institute of Dental Sciences, New Delhi, India.

Objective: To analyze the effects of presurgical nasoalveolar molding (PNAM) in newborns with cleft lip and palate and evaluate its postsurgical stability at 1-year follow-up using a nasal stent.

Design: Prospective clinical trial.

Setting: Department of Orthodontics, Maulana Azad Institute of Dental Sciences, Delhi. Read More

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http://dx.doi.org/10.1177/1055665620906293DOI Listing

Wireless Sensing of Lower Lip and Thumb-Index Finger 'Ramp-and-Hold' Isometric Force Dynamics in a Small Cohort of Unilateral MCA Stroke: Discussion of Preliminary Findings.

Sensors (Basel) 2020 Feb 23;20(4). Epub 2020 Feb 23.

Department of Special Education and Communication Disorders, University of Nebraska, 141 Barkley Memorial Center, Lincoln, NE 68583-0738, USA.

Automated wireless sensing of force dynamics during a visuomotor control task was used to rapidly assess residual motor function during finger pinch (right and left hand) and lower lip compression in a cohort of seven adult males with chronic, unilateral middle cerebral artery (MCA) stroke with infarct confirmed by anatomic magnetic resonance imaging (MRI). A matched cohort of 25 neurotypical adult males served as controls. Dependent variables were extracted from digitized records of 'ramp-and-hold' isometric contractions to target levels (0. Read More

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http://dx.doi.org/10.3390/s20041221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070866PMC
February 2020

Maxillomandibular Transverse Osteodistraction: A Multidisciplinary Case Report with 30-Month Follow-Up.

Case Rep Dent 2020 31;2020:3856412. Epub 2020 Jan 31.

Division of Maxillofacial Surgery, Department of Surgical Sciences, Università degli studi di Torino, Città della Salute e delle Scienza Hospital, Corso A.M. Dogliotti 14, Turin 10126, Italy.

Aim: To describe a multidisciplinary treatment to correct a severe II class malocclusion with reduced both maxillary and mandibular transverse dimensions and dental crowding. . A 17-year-old young woman presented with an increased overjet complaining chiefly of forwardly placed upper front teeth and unpleasant smile aesthetics. Read More

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http://dx.doi.org/10.1155/2020/3856412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016482PMC
January 2020

Ingenol mebutate treatment for actinic cheilitis: clinical, histopathological and p53 profile of 14 cases.

J Dermatolog Treat 2020 Feb 27:1-4. Epub 2020 Feb 27.

Department of Dermatology, Santa Casa de Curitiba Hospital, Paraná, Brazil.

: Actinic cheilitis (AC) is part of a spectral disease of keratinocyte carcinomas considered by some authors an early stage of squamous cell carcinoma. Treatment options for AC can be lesion and field-directed therapies. Ingenol mebutate (IM) induces rapid and direct cell death and immune responses being able to destruct dysplastic cells. Read More

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http://dx.doi.org/10.1080/09546634.2020.1724865DOI Listing
February 2020

Effect of Weissella cibaria on the reduction of periodontal tissue destruction in mice.

J Periodontol 2020 Feb 3. Epub 2020 Feb 3.

Department of Periodontology and Research Institute of Oral Sciences, Gangneung-Wonju National University College of Dentistry, Gangneung, Korea.

Background: Periodontitis is associated with dysbiosis of microbial flora in the oral cavity. We evaluated the effects of an oral care probiotic, Weissella cibaria CMU, on periodontal tissue destruction and regulation of inflammatory cytokines in mice with ligature-induced periodontitis (LIP).

Methods: Fourteen-day LIP model was used. Read More

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http://dx.doi.org/10.1002/JPER.19-0288DOI Listing
February 2020

Improvement in the Quality of Life of a Patient of Ectodermal Dysplasia with Reconstructive Surgeries.

J Cutan Aesthet Surg 2019 Oct-Dec;12(4):244-247

Department of Dermatology, Dr. D. Y. Patil Medical College, Hospital & Research Centre, Pune, Maharashtra, India.

Ectodermal dysplasias are a complex group of heterogenous, heritable disorders entailing two or more developmental abnormalities in ectodermal structures, such as hair, teeth, nails, and/or sweat glands. The most common subtype of these disorders is X-linked hypohidrotic that significantly impairs the quality of life of its sufferers. A 15-year-old boy, who sought the treatment for protuberant lips, saddle nose, dental anomalies, fine sparse hair, decreased sweating, intolerance to heat and photosensitivity, experienced dramatic improvement in his quality of life and confidence with aesthetic correction comprising autologous fat grafting, rhinoplasty, lip reduction, microblading and comprehensive prosthodontic and orthodontic treatments undertaken in collaboration with dental and plastic surgery departments and expert psychological counseling. Read More

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http://dx.doi.org/10.4103/JCAS.JCAS_17_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6967165PMC
February 2020

Lip Repositioning, Aesthetic Crown Lengthening, and Gingival Depigmentation: A Combined Approach for a Gummy Smile Makeover.

J Cutan Aesthet Surg 2019 Oct-Dec;12(4):240-243

Head Dentist, Health Care Centre, Mumbai, Maharashtra, India.

This clinical report describes the successful use of aesthetic crown lengthening, lip-repositioning technique as well as gingival depigmentation for the reduction of excessive gingival display and dark gums, respectively. Lip-repositioning technique was performed with the main objective of reducing gummy smile by limiting the retraction of elevator muscles (e.g. Read More

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http://dx.doi.org/10.4103/JCAS.JCAS_25_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6967167PMC
February 2020