Angew Chem Int Ed Engl 2022 May 17:e202204570. Epub 2022 May 17.
Department of Chemistry and Biochemistry, Materials Science Institute, Knight Campus for Accelerating Scientific Impact, and Institute of Molecular Biology, University of Oregon, Eugene, OR 97403-1253, USA.
S/N crosstalk species derived from the interconnected reactivity of H S and NO facilitate the transport of reactive sulfur and nitrogen species in signaling, transport, and regulatory processes. We report here that simple Fe ions, such as those that are bioavailable in the labile iron pool (LIP), react with thionitrite (SNO ) and perthionitrite (SSNO ) to yield the dinitrosyl iron complex [Fe(NO) (S )] . In the reaction of FeCl with SNO we were able to isolate the unstable intermediate hydrosulfido mononitrosyl iron complex [FeCl (NO)(SH)] , which was characterized by X-ray crystallography. Read More