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    Lower lip reconstruction using a skin-mucosa Abbe-Estlander flap after squamous cell carcinoma excision.
    An Bras Dermatol 2017 Mar-Apr;92(2):260-262
    Department of Dermatology, San Cecilio University Hospital - Granada. Spain.
    Lips are structures that play an essential role in aesthetics and in different functions such as nutrition and speech. The complex anatomy of the lips - with three different layers composed of skin, mucosa, and muscles - makes surgical management of this area a therapeutic challenge. The use of flaps for the reconstruction of large defects with low risk of necrosis is possible given the abundant blood supply of the lips. Read More

    Lip reconstruction using a functioning serratus anterior free flap: preliminary study.
    Int J Oral Maxillofac Surg 2017 May 19. Epub 2017 May 19.
    Department of Plastic, Reconstructive and Aesthetic Surgery, Necmettin Erbakan University, Medical Faculty of Meram, Konya, Turkey.
    Reconstructive surgery to the lips requires the replacement of defective tissues with similarly functioning tissues. While non-dynamic free tissue transfers provide adequate lower lip reconstruction, improved benefits may be obtained with innervated free muscle flaps. This study reports the use of innervated serratus anterior muscle free flaps for lip reconstruction in five patients. Read More

    Performance of algorithms that reconstruct missing transverse momentum in [Formula: see text]= 8 TeV proton-proton collisions in the ATLAS detector.
    Eur Phys J C Part Fields 2017 13;77(4):241. Epub 2017 Apr 13.
    CERN, Geneva, Switzerland.
    The reconstruction and calibration algorithms used to calculate missing transverse momentum ([Formula: see text] ) with the ATLAS detector exploit energy deposits in the calorimeter and tracks reconstructed in the inner detector as well as the muon spectrometer. Various strategies are used to suppress effects arising from additional proton-proton interactions, called pileup, concurrent with the hard-scatter processes. Tracking information is used to distinguish contributions from the pileup interactions using their vertex separation along the beam axis. Read More

    Eyelid Reconstruction Using Oral Mucosa and Ear Cartilage Strips as Sandwich Grafting.
    Plast Reconstr Surg Glob Open 2017 Apr 19;5(4):e1301. Epub 2017 Apr 19.
    Department of Plastic and Reconstructive Surgery, New Tokyo Hospital, Chiba, Japan; Department of Plastic and Reconstructive Surgery, Asakadai Central General Hospital, Saitama, Japan; and Department of Plastic and Reconstructive Surgery, National Defense Medical College, Saitama, Japan.
    Background: The eyelid structure can be divided into an inner layer and an outer layer. Reconstruction of a full-thickness eyelid defect is accomplished by full-thickness composite tissue transfer or combined layered reconstruction. We present a new technique for inner layer reconstruction using ear cartilage and oral mucosa. Read More

    Reconstructing Discontinuous Facial Defects with Simultaneous Ulnar Perforator Free Flaps.
    Plast Reconstr Surg Glob Open 2017 Apr 7;5(4):e1291. Epub 2017 Apr 7.
    Department of Otolaryngology, University of Colorado School of Medicine, Aurora, Colo.; and Division of Plastic Surgery, Departments of Surgery and Otolaryngology, Children's Hospital Colorado and University of Colorado School of Medicine, Aurora, Colo.
    Multiple, simultaneous skin cancers of the face are common. This is the first description of reconstructing discontinuous facial defects (i.e. Read More

    Vermillion Reconstruction With Anal Verge Transitional Epithelium: Turning Things Upside Down.
    J Burn Care Res 2017 May 4. Epub 2017 May 4.
    From the *Section of Plastic Surgery, Department of Surgery, University of Michigan Health System, University of Michigan Medical School, Ann Arbor; and †Division of Plastic Surgery, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston.
    Postburn lip deformities pose a significant set of challenges to reconstructive burn surgeons because of the complex anatomy, diverse functions, and specialized nature of the lip tissues. There has been a paucity of literature on restoration of the vermillion to date. The authors report on two patients who suffered burn injuries resulting in significant lip deformities who underwent a novel method of vermillion reconstruction with a full thickness anal verge skin graft. Read More

    Sphincter-Sparing Excision and Reconstruction Using Facial Artery Perforator Flaps for Lower Lip Carcinoma.
    J Oral Maxillofac Surg 2017 Apr 8. Epub 2017 Apr 8.
    Specialist, Pathology Department, Yildirim Beyazit University, Ataturk Training and Research Hospital, Ankara, Turkey.
    Purpose: This article discusses the results of orbicularis oris muscle-sparing surgery and reconstruction of defects through the use of facial artery perforator flaps and mucosal advancement flaps.

    Patients And Methods: Patients with lower lip carcinoma were evaluated retrospectively. Patients who underwent reconstruction with facial artery perforator flaps and mucosal advancement flaps with clear surgical margins and no muscle invasion were included in this study. Read More

    Full Mouth Reconstruction of a Skeletal Class II Division 1 Patient with Adenoid Cystic Carcinoma Using an Interim Immediate Obturator and a Definitive Obturator.
    Case Rep Dent 2017 4;2017:5458617. Epub 2017 Apr 4.
    Dental Research Center, Department of Prosthodontics, Faculty of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
    A 61-year-old female patient with adenoid cystic carcinoma (ACC) of the right maxilla and Angle class II division 1 malocclusion had received a subtotal maxillectomy in right side and used a conventional clasp-retained obturator. After implants placement, a maxillary interim immediate obturator (IIO) and then a definitive obturator using six endosseous implants were fabricated. During one-year follow-up, the patient was completely satisfied. Read More

    Development of a facescan 3D facial reconstruction technology method for quantitative evaluation of cheilitis granulomatosa.
    Sci Rep 2017 May 2;7(1):1295. Epub 2017 May 2.
    Department of Oral Medicine, Peking University School and Hospital of Stomatology & National Engineering Laboratory for Digital and Material Technology of Stomatology, 22 South Zhongguancun Ave, Haidian District, Beijing, 100081, China.
    We explored the applicability of Facescan three-dimensional (3D) facial reconstruction technology for adjunctive diagnosis and therapeutic evaluation of cheilitis granulomatosa (CG) in 33 patients with CG and 29 healthy controls at the Dept. of Oral Medicine, Peking University, School and Hospital of Stomatology (PKUSS), from January 2015 to May 2016. The Facescan structured-light 3D facial reconstruction scanner was used to scan the scope of lips in both groups, in order to acquire 3D morphological data of the lips. Read More

    Surgical correction of mandibular hypoplasia in hemifacial microsomia: A retrospective study in 39 patients.
    J Craniomaxillofac Surg 2017 Mar 30. Epub 2017 Mar 30.
    Stomatology and Maxillo-facial Surgery Unit, Nantes University Hospital, 1 Place Alexis-Ricordeau, 44093 Nantes Cedex 1, France.
    Purpose: Repair of the mandibular deformity in hemifacial microsomia (HFM) remains controversial, and there is scant information in the literature regarding the late outcomes. The aim of this study was to evaluate architectural and aesthetic long-term outcomes for primary mandibular surgery in patients with HFM.

    Materials And Methods: Thirty-nine patients with types II and type III HFM were included in this retrospective study. Read More

    Resection of upper lip adenoid cystic carcinoma and reconstruction with reverse Yu flap: Report of three cases and a literature review.
    Mol Clin Oncol 2017 Mar 3;6(3):444-450. Epub 2017 Feb 3.
    Department of Oral and Maxillofacial Surgery, Virgen Del Rocio University Hospital, 41013 Seville, Spain.
    The present study aimed to describe the techniques that were used, and the results obtained, with the reverse Yu flap to reconstruct medium-sized upper lip defects following resection for adenoid cystic carcinoma (ACC). Data concerning the clinical and pathological characteristics of tumours, the size and location of the defects, surgical resection and the reconstructive procedure used were evaluated in three patients, as well as postoperative complications and outcomes. In all cases, a complete surgical removal of ACC was achieved with clear margins of at least 1 cm. Read More

    The Transposition Flap for the Reconstruction of Lower Cutaneous Lip Defects.
    J Drugs Dermatol 2017 Apr;16(4):385-387

    The lower cutaneous lip is a highly visible and functionally sensitive unit, and numerous factors must be considered when deciding on the optimal repair for defects in this area. The transposition flap represents an excellent option in the reconstruction of larger lower cutaneous lip defects. We describe the use of random pattern transposition flaps for the repair of lower lateral cutaneous lip defects. Read More


    A New Design for Reconstruction of Nasal Dimensions during the Primary Repair of Unilateral Cleft Lip.
    Plast Reconstr Surg 2017 Jun;139(6):1376e-1377e
    State Key Laboratory of Oral Disease, West China College of Stomatology, Chengdu, People's Republic of China State Key Laboratory of Oral Disease, West China College of Stomatology, and Department of Cleft Lip and Palate Surgery, West China Stomatological Hospital, Sichuan University, Chengdu, People's Republic of China State Key Laboratory of Oral Disease, West China College of Stomatology, Chengdu, People's Republic of China, Department of Growth and Development and Section of Orthodontics, School of Dentistry, University of California, Los Angeles, Los Angeles, Calif. State Key Laboratory of Oral Disease, West China College of Stomatology, and Department of Cleft Lip and Palate Surgery, West China Stomatological Hospital, Sichuan University, Chengdu, People's Republic of China.

    Transoral Cross-Lip (Abbé-Estlander) Flap as a Viable and Effective Reconstructive Option in Middle Lower Lip Defect Reconstruction.
    Ann Dermatol 2017 Apr 24;29(2):210-214. Epub 2017 Mar 24.
    Department of Dermatology, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu, Korea.
    The Abbé-Estlander flap surgery is a cross-lip procedure that is valuable in repairing a defect on the lower lip using a full-thickness flap, consisting of the skin, muscle and mucosa, from the upper lip. As usefulness and practicality of the flap in reconstruction of lower lip surgical defects in Asian ethnicity have not been documented, the authors present a case of successful lower lip reconstruction with a staged, Abbé-Estlander lip switching flap with commissuroplasty as an illustrative example. A 71-year-old male has presented with an ulcerating lip nodule in the middle one third of the lower lip, measuring about 1. Read More

    More than just the helix: A series of free flaps from the ear.
    Microsurgery 2017 Apr 1. Epub 2017 Apr 1.
    Department of Plastic Surgery, Töölö Hospital, Helsinki University Hospital, University of Helsinki, Finland.
    Aim: We herein present our experience using free flaps harvested from the ear region in facial, nasal and intraoral reconstruction.

    Patients And Methods: Between 2011 and 2016, 19 patients underwent reconstruction using 20 free flaps from the ear region based on the superficial temporal vessels. There were 10 males and 9 females with a mean age of 57 years. Read More

    A Comparative Analysis of rhBMP-2/DBM vs. ICBG for Secondary Alveolar Bone Grafts in Patients with Cleft Lip and Palate: Review of 501 Cases.
    Plast Reconstr Surg 2017 Mar 31. Epub 2017 Mar 31.
    1Division of Plastic and Maxillofacial Surgery, Children's Hospital Los Angeles, CA, USA 2 Division of Plastic and Reconstructive Surgery, University of Southern California, CA, USA 3Department of Oral and Maxillofacial Surgery, University of Southern California, School of Dentistry, CA, USA 4Devision of Plastic Surgery, University of Michigan, Ann Arbor, MI, USA 5Division of Plastic Surgery of New York-Presbyterian/Columbia, New York-Presbyterian/Morgan Stanley Children's Hospital, NY, USA 6Oregon Health & Science University, Portland, OR, USA 7 Ostrow School of Dentistry, University of Southern California, CA, USA 8Division of Dentistry and Orthodontics, Children's Hospital Los Angeles, CA USA.
    Background: Alveolar cleft reconstruction using iliac crest bone graft(ICBG) is considered standard of care for children with complete cleft lip and palate at the time of mixed dentition. Harvesting bone may result in donor site morbidity, additional operating time and length of hospitalization. Recombinant human bone morphogenetic protein(rhBMP)-2 with a demineralized bone matrix(DBM) was used as an alternative bone source for alveolar cleft reconstruction. Read More

    Near-total lower lip reconstruction: combined Karapandzic and Bernard-Burrow-Webster flap.
    Acta Dermatovenerol Alp Pannonica Adriat 2017 Mar;26(1):19-20
    Dermatology Department, Trás-os- Montes e Alto Douro Central Hospital, Vila Real, Portugal.
    Lip carcinoma is a common cancer of the head and neck region. It more often affects the lower lip (> 90%), and squamous cell carcinoma represents 95% of the cases. The authors present a reconstruction of the lower lip combining two classical flaps: the Karapandzic and Bernard-Burrow-Webster flap. Read More

    Cleft Septorhinoplasty: Form and Function.
    Facial Plast Surg Clin North Am 2017 May;25(2):223-238
    Facial Plastic and Reconstructive Surgery, Department of Otolaryngology-Head and Neck Surgery, UC Davis Medical Center, 2521 Stockton Boulevard, Suite 7200, Sacramento, CA 95817, USA. Electronic address:
    Nasal deformity associated with typical cleft lip can cause aesthetic and functional issues that are difficult to address. The degree of secondary nasal deformity is based on the extent of the original cleft deformity, growth over time, and any prior surgical correction to the nose or lip. Repair and reconstruction of these deformities require comprehensive understanding of embryologic growth, the cleft anatomy, as well as meticulous surgical technique and using a spectrum of structural grafting. Read More

    Platysma Motor Nerve Transfer for Restoring Marginal Mandibular Nerve Function.
    Plast Reconstr Surg Glob Open 2016 12 13;4(12):e1164. Epub 2016 Dec 13.
    Department of Plastic and Maxillofacial Surgery, Uppsala University Hospital, Uppsala, Sweden; Department of Surgical Sciences, Uppsala University, Uppsala, Sweden; and Center of Anatomy and Cell Biology and Division of Plastic and Reconstructive Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria.
    Background: Injuries of the marginal mandibular nerve (MMN) of the facial nerve result in paralysis of the lower lip muscle depressors and an asymmetrical smile. Nerve reconstruction, when possible, is the method of choice; however, in cases of long nerve gaps or delayed nerve reconstruction, conventional nerve repairs may be difficult to perform or may provide suboptimal outcomes. Herein, we investigate the anatomical technical feasibility of transfer of the platysma motor nerve (PMN) to the MMN for restoration of lower lip function, and we present a clinical case where this nerve transfer was successfully performed. Read More

    Transoral robotic surgery with radial forearm free flap reconstruction: case control analysis.
    J Otolaryngol Head Neck Surg 2017 Mar 14;46(1):20. Epub 2017 Mar 14.
    Department of Surgery, Division of Otolaryngology-Head & Neck Surgery, University of Alberta, 8440-112 st, 1E4 Walter Mackenzie Centre, Edmonton, AB, T6G 2B7, Canada.
    Background: The resection of large oropharyngeal tumors traditionally involves a lip-splitting mandibulotomy for adequate margin visualization and free flap reconstruction of the surgical defect. Transoral robotic surgery (TORS) has emerged as a technique that can resect large and complex oropharyngeal tumors, avoiding a lip-splitting approach. The aim of this study is to compare the lip-splitting mandibulotomy approach versus TORS for the management of advanced stage oropharyngeal carcinomas. Read More

    Digitalized analysis of philtral anatomy for planning individual treatment.
    Surg Radiol Anat 2017 Mar 13. Epub 2017 Mar 13.
    Department of Anatomy, Faculty of Medicine, Ege University, 35100, Izmir, Turkey.
    Objective: Restoration of the philtral region following traumatic, cleft, and tumor surgeries is often difficult due to influence of this feature to whole facial beauty. The aim of this study is to investigate the types and measurements of the philtrum and its relationship with the upper lip using a software.

    Methods: Standard personal photographs of the philtral region were obtained from 200 young adults participated in this study. Read More

    Aesthetic Reconstruction of the Frontotemporal Region: The Extended A-T Plasty, A Workhorse Revisited.
    Ann Plast Surg 2017 Mar 7. Epub 2017 Mar 7.
    From the Unit of Plastic Surgery and Dermatology, "Campus Bio-Medico di Roma" University, Rome, Italy.
    Background: A-T plasty has long been a workhorse for defects located around the eyebrow or in the upper and lower lip. It allows like-with-like reconstruction with placement of the scars in natural creases or subunit junctions. In this article, the authors describe their refined technique to specifically address moderate to large size defects of the frontotemporal, preauricular, and zygomatic regions. Read More

    Congenital double-level cervical spondylolysis: a case report and review of the literature.
    Eur Spine J 2017 Feb 28. Epub 2017 Feb 28.
    Department of Orthopaedic Surgery, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
    Purpose: We report a rare Japanese female who was affected with three genetic-linked diseases: double-level cervical bilateral spondylolysis in association with spina bifida occulta, cleft lip and monostotic fibrous dysplasia of the right proximal femur. The case was considered to be congenital in origin. We also review the pertinent literature of cervical spondylolysis, with a focus on the pathogenesis of multiple-level cervical spondylolysis. Read More

    Can I Make Robotic Surgery Make Sense in My Practice?
    Plast Reconstr Surg 2017 Mar;139(3):781e-792e
    Houston, Texas From The University of Texas, M. D. Anderson Cancer Center.
    Over the past 10 years, robotic technology has had a significant impact on minimally invasive surgery. Because plastic surgery is rooted in "open" techniques, robotic applications in the specialty have been slow to emerge. That said, robotic technology possesses superhuman precision and high-definition, three-dimensional optics that are promising attributes in the hands of the plastic surgeon. Read More

    Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 10. Parental perceptions of appearance and treatment outcomes in their 5-year-old child.
    J Plast Surg Hand Surg 2017 Feb;51(1):81-87
    n Centre for Appearance Research , University of the West of England , Bristol , UK.
    Background And Aim: Few studies have explored children's emotional and behavioural reactions to cleft surgery and treatment-related stress. The objective was to investigate parents' evaluations of appearance and treatment outcomes in their 5-year-old child with unilateral cleft lip and palate (UCLP), and their perceptions of how their child was coping with treatment, comparing this information with recorded postsurgical complications.

    Design: Three parallel group randomised clinical trials were undertaken as an international multicentre study by 10 cleft teams in five countries: Denmark, Finland, Sweden, Norway, and the UK. Read More

    Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 7. Occlusion in 5 year-olds according to the Huddart and Bodenham index.
    J Plast Surg Hand Surg 2017 Feb;51(1):58-63
    e Department of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway.
    Background And Aim: Good dentofacial development and good occlusion are main goals in the treatment of UCLP. The aim was to evaluate dental occlusion at age 5 years with the Huddart and Bodenham index after four different protocols of primary surgery for UCLP.

    Design: Three parallel randomised controlled trials were undertaken as an international multicentre study by 10 cleft teams in five countries: Denmark, Finland, Sweden, Norway, and the UK. Read More

    Application of Computer-Aided Design and Customized Implants in the Reconstruction of Pyriform Aperture Defects Secondary to Unilateral Cleft Lip and Palate.
    J Craniofac Surg 2017 Feb 15. Epub 2017 Feb 15.
    Department of Oral and Craniomaxillofacial Surgery, Shanghai Key Laboratory of Stomatology, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
    Purpose: To design and develop customized implants with the rapid prototyping (RP) technique in order to reconstruct the defected pyriform aperture.

    Methods: A 3-dimensional digital model was reconstructed with the software proplan CMF based on the computed tomography data of the patient's skeleton. Then an individualized implant was designed by computer-aided design (CAD) and prepared with the RP technique. Read More

    Sequence of Surgical Reconstruction in a Child With Cleft Lip and Palate Associated With Congenital Facial Teratomas.
    J Craniofac Surg 2017 Feb 15. Epub 2017 Feb 15.
    Division of Plastic Surgery, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia.
    We describe a case of left homolateral complete cleft lip/palate associated with a congenital left maxillary teratoma and left orbital teratoma. The patient required step-by-step reconstruction that first included resection of the 2 teratomas in consideration of cleft lip repair, cleft palate repair, and correction of the left periorbital anomalies, which were performed later. After performing all the necessary procedures, complete resection of the tumors and correction of the anomalies associated with the lip, palate, and left orbit were achieved. Read More

    Functional Outcomes and Complications of Robot-Assisted Free Flap Oropharyngeal Reconstruction.
    Ann Plast Surg 2017 Mar;78(3 Suppl 2):S76-S82
    From the *Division of Plastic and Reconstructive Surgery, Department of Surgery, †Department of Otolaryngology, Taichung Veterans General Hospital, Taichung; and ‡Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan, Republic of China.
    Background: Robotic surgical systems provide a clear, magnified 3-dimensional visualization as well as precise, stable instrumental movement, thereby minimizing technical difficulties that may be encountered in the surgical treatment of oropharyngeal tumors. This study assessed the outcomes of robotic-assisted free flap oropharyngeal reconstruction compared with those of conventional free flap reconstruction.

    Materials And Methods: A retrospective review of 47 patients who underwent reconstructive operations using a free radial forearm fasciocutaneous flap for oropharyngeal defects was conducted over a 20-month period (May 2013-December 2014). Read More

    Labia Majora Share.
    Arch Plast Surg 2017 Jan 20;44(1):80-84. Epub 2017 Jan 20.
    Division of Plastic, Reconstructive and Aesthetic Surgery, Department of General Surgery, National University Health System, Singapore.
    Defects involving specialised areas with characteristic anatomical features, such as the nipple, upper eyelid, and lip, benefit greatly from the use of sharing procedures. The vulva, a complex 3-dimensional structure, can also be reconstructed through a sharing procedure drawing upon the contralateral vulva. In this report, we present the interesting case of a patient with chronic, massive, localised lymphedema of her left labia majora that was resected in 2011. Read More

    Double-paddle peroneal flap for extensive lip defect reconstruction.
    Microsurgery 2017 Feb 7. Epub 2017 Feb 7.
    Division of Plastic and Reconstructive Surgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
    Introduction: Today, reconstructive surgeons offer an array of options to reconstruct the lip defects. Herein we present our experience of using free double-paddle peroneal flaps for extensive lip defect reconstruction.

    Patients And Methods: From 1996 to 2014, 16 patients with extensive lip defects after tumor ablation were included. Read More

    Hearing sensitivity in adults with a unilateral cleft lip and palate after two-stage palatoplasty.
    Int J Pediatr Otorhinolaryngol 2017 Mar 26;94:76-81. Epub 2016 Dec 26.
    Department of Plastic Surgery, University Medical Centre Utrecht, P.O. Box 85090, 3508 AB, Utrecht, Utrecht, The Netherlands.
    Objective: To evaluate long-term hearing and middle ear status in patients treated for a unilateral complete cleft lip and palate (UCLP) by two-stage palatoplasty.

    Methods: Forty-nine UCLP patients aged 17 years and older were included in this retrospective study. Patients were invited for a multidisciplinary long-term follow-up of their treatment at a tertiary center for craniofacial surgery in the Netherlands. Read More

    Face Transplantation: Partial Graft Loss of the First Case 10 Years Later.
    Am J Transplant 2017 Jan 31. Epub 2017 Jan 31.
    Department of Maxillofacial Surgery, CHU Amiens-Picardie, Facing Faces Institute, Amiens, France.
    Ten years after the first face transplantation, we report the partial loss of this graft. After two episodes of acute rejection (AR) occurred and completely reversed in the first posttransplantation year, at 90 months posttransplantation the patient developed de novo class II donor-specific antibodies, without clinical signs of AR. Some months later, she developed several skin rejection episodes treated with steroid pulses. Read More

    Incidence of Palatal Fistula at Time of Secondary Alveolar Cleft Reconstruction.
    Cleft Palate Craniofac J 2017 Jan 31. Epub 2017 Jan 31.
    Objective:   We aim to establish consistent time points for evaluating palatal fistula incidence to standardize reporting practices and clarify prospective literature.

    Design:   An institutional retrospective chart review was conducted on 76 patients with unilateral or bilateral complete cleft lip and palate who underwent secondary alveolar bone grafting between 2006 and 2015.

    Main Outcome Measures:   Early fistula incidence rates were reported prior to maxillary expansion, and late fistula rates were reported at the time of alveolar bone grafting. Read More

    Haplotype-based gene-gene interaction of bone morphogenetic protein 4 and interferon regulatory factor 6 in the etiology of non-syndromic cleft lip with or without cleft palate in a Chilean population.
    Eur J Oral Sci 2017 Apr 30;125(2):102-109. Epub 2017 Jan 30.
    Instituto de Investigación en Ciencias Odontológicas, Facultad de Odontología, Universidad de Chile, Santiago, Chile.
    Non-syndromic cleft lip with or without cleft palate (NSCL/P) is the most common craniofacial birth defect in humans, the etiology of which can be dependent on the interactions of multiple genes. We previously reported haplotype associations for polymorphic variants of interferon regulatory factor 6 (IRF6), msh homeobox 1 (MSX1), bone morphogenetic protein 4 (BMP4), and transforming growth factor beta 3 (TGFB3) in Chile. Here, we analyzed the haplotype-based gene-gene interaction for markers of these genes and NSCL/P risk in the Chilean population. Read More

    Novel use of an ultrasonic bone aspirator for extended endoscopic frontal sinusotomy: A feasibility study.
    Am J Rhinol Allergy 2016 Nov;30(6):443-447
    Division of Otolaryngology, George Washington University Medical Center, Washington, D.C., USA.
    Introduction: Extended endoscopic frontal sinusotomy is often required for surgical management of anterior skull base pathology. Such approaches are necessary for access to pathology and maintenance of postoperative frontal sinus outflow tract drainage. Cold steel instrumentation and endoscopic high-speed microdrills are typically used for bony removal during extended frontal sinus approaches but are associated with certain drawbacks, such as thermal injury and obscuration of the surgical field with bone dust. Read More

    Implant-Retained Prosthetic Auricular Reconstruction in a Hemifacial Microsomia Individual: A Clinical Report.
    Int J Prosthodont 2017 Jan/Feb;30(1):54-57
    Hemifacial microsomia is the second most frequently encountered congenital facial anomaly after cleft lip and palate. This case history report describes a two-implant-supported auricular prosthetic reconstruction in a young patient with an absent auricle and malpositioned lobule. The selected treatment protocol was chosen because of its superior retention when compared with alternative retention systems. Read More

    The versatility of the Karapandzic flap: A review of 65 cases with patient-reported outcomes.
    J Craniomaxillofac Surg 2017 Feb 14;45(2):325-329. Epub 2016 Dec 14.
    Oral and Maxillofacial Surgery Department, York Teaching Hospitals NHS Foundation Trust, The York Hospital, Wigginton Road, York, YO31 8HE, United Kingdom.
    Objective: The Karapandzic flap is an established technique for reconstruction of large lip defects and in our experience is particularly valuable in repair of the upper lateral lip and the commissures as well. We present our experience in a case series of 65 patients under one consultant.

    Method: This is a retrospective study of patients who underwent Karapandzic flap repair for lip defects following cancer resection from 2007 to 2014 in North Yorkshire. Read More

    Intraflagellar transport 88 (IFT88) is crucial for craniofacial development in mice and is a candidate gene for human cleft lip and palate.
    Hum Mol Genet 2017 Mar;26(5):860-872
    Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, CA 90033, USA.
    Ciliopathies are pleiotropic human diseases resulting from defects of the primary cilium, and these patients often have cleft lip and palate. IFT88 is required for the assembly and function of the primary cilia, which mediate the activity of key developmental signaling pathways. Through whole exome sequencing of a family of three affected siblings with isolated cleft lip and palate, we discovered that they share a novel missense mutation in IFT88 (c. Read More

    Horizontally Opposed V-Y Advancement Flaps for Surgical Reconstruction of Central Upper Lip Defects.
    J Craniofac Surg 2017 Mar;28(2):578-579
    University of Arizona Cancer Center, Phoenix, AZ Division of Dermatology, University of Arizona, Tucson, AZ Dermatology and Plastic Surgery of Arizona, Tucson, AZ Northwestern University Feinberg School of Medicine, Chicago, IL.

    Assessment of complete unilateral cleft lip and palate patients: Determination of factors effecting dental arch relationships.
    Int J Pediatr Otorhinolaryngol 2017 Jan 11;92:70-74. Epub 2016 Nov 11.
    Forensic Dentistry Unit, School of Dental Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia. Electronic address:
    Objectives: The purpose of the current study was to assess the treatment outcome of non-syndromic patients having complete unilateral cleft lip and palate (CUCLP) by using GOSLON index and to determine any association of pre and/or postnatal factors with the treatment outcome.

    Materials And Methods: One hundred and one sets of dental models of patients having CUCLP were assessed in this retrospective study. Five examiners that were blinded to case-specific information scored the dental models at two instances with an interval of two weeks to ensure memory bias elimination (5 × 101 × 2 = 1010 observations). Read More

    Pediatric rhinoplasty: A discussion of perioperative considerations and systematic review.
    Int J Pediatr Otorhinolaryngol 2017 Jan 26;92:11-16. Epub 2016 Oct 26.
    Department of Otolaryngology - Head and Neck Surgery, Wayne State University School of Medicine, Detroit, MI, USA; Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology - Head and Neck Surgery, Wayne State University School of Medicine, Detroit, MI, USA.
    Objectives: Pediatric rhinoplasty has traditionally raised numerous concerns, including its impact on growth as well as the psychological sequelae of undergoing a potentially appearance-altering procedure. Our objective was to critically evaluate available individual patient data relevant to pediatric rhinoplasty, and further discuss perioperative considerations.

    Methods: A systematic review was conducted using PubMed/MEDLINE databases. Read More

    The temporalis muscle flap for reconstruction of soft palate and lateral oropharyngeal wall after transoral robotic surgery.
    Auris Nasus Larynx 2016 Dec 20. Epub 2016 Dec 20.
    Department of Head-Neck Surgery, Otolaryngology, Head-Neck and Oral Surgery Unit, Morgagni Pierantoni Hospital, Azienda USL della Romagna, Forlì, Italy.
    Trans Oral robotic surgery (TORS) is a prominent surgical approach for the resection of oropharyngeal tumors without division of the lip and mandible. The current practice following TORS is to allow the defect to heal by secondary intention, but some defects following TORS are large and complex enough to benefit soft-tissue coverage. In the free flap era, regional flaps are often overlooked albeit they still represent a valid alternative. Read More

    Nasopalatine Island Advancement Flap.
    J Craniofac Surg 2016 Nov;27(8):2190-2191
    *Oral and Maxillofacial Diseases Research Center†Dental Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
    Background: Anterior maxilla is a high esthetic region of the mouth. Some flaps are introduced for bone graft coverage, mainly based on secondary epithelization of connective tissue-periosteal tissues. This article evaluates the versatility of a new mucoperiosteal flap for reproducible coverage in anterior maxilla. Read More

    A New Surgical Approach for Tessier No. 4 Facial Cleft Reconstruction: Lip-Rescue Flap.
    J Craniofac Surg 2016 Nov;27(8):2138-2140
    *Plastic Reconstructive and Aesthetic Surgery Clinic, Ankara Diskapi Yildirim Beyazit Education And Research Hospital, Ankara, Turkey†Plastic Reconstructive and Aesthetic Surgery Department, Showa University School of Medicine, Tokyo, Japan‡Plastic Reconstructive and Aesthetic Surgery Department, Ankara Yildirim Beyazit University, Ankara, Turkey.
    Craniofacial clefts are rare, severe challenges for surgeons about which there is limited literature. Tessier Number 4 (No. 4) clefts are one of the most complex craniofacial anomalies and present difficulties in surgical treatment. Read More

    Cleft Lip Repair: Through the Looking Glass.
    J Craniofac Surg 2016 Nov;27(8):2031-2035
    Division of Plastic and Reconstructive Surgery, Icahn School of Medicine at Mount Sinai, New York, NY.
    The goal of cleft lip repair is an anatomic re-creation of the normal lip elements with no vertical discrepancy between the affected and normal sides of the central philtral element. Frequently, the repaired lip appears short in the vertical dimension despite careful preoperative measurements and intraoperative maneuvers. Some may be due to postoperative scar contraction, but some may be due to a failure to consider the internal surface when reconstructing the lip. Read More

    Two-Thirds Lip Defects: A New Combined Reconstructive Technique for Patients With Epithelial Cancer.
    J Craniofac Surg 2016 Nov;27(8):1995-2000
    *Department of Experimental and Clinical Medicine, University "Magna Græcia" of Catanzaro, Catanzaro†Department of Surgery "P Valdoni," University of Rome La Sapienza, Rome, Italy.
    Background: The lips are a common site prone to squamous cell carcinomas, which arise in the facial region. There are different techniques to reconstruct the excised lip region, according to dimensions, area, and position of the tumor. The authors describe a new technique of lip reconstruction born from a combination between a nasolabial flap and adipose tissue transplant. Read More

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