Clin Exp Dermatol 2017 Jun 14. Epub 2017 Jun 14.

Dermatology Department, American University of Beirut Medical Center, Beirut, Lebanon.

Br J Dermatol 2017 May;176(5):e96

Department of Dermatology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.

Am J Dermatopathol 2017 Feb;39(2):144-149

*Department of Pathology, Clinical Hospital, Santiago de Compostela, Spain; †Department of Pathology and Forensic Sciences, University of Santiago de Compostela, Santiago de Compostela, Spain; ‡Department of Dermatology, Clinical Hospital, Santiago de Compostela, Spain; and §Department of Dermatology, Hospital da Barbanza, Ribeira, Spain.

Linear dermatoses are unusual entities whose distribution reflects cutaneous mosaicism, even when they occur in adult life. Adult blaschkitis (AB) and lichen striatus (LS) always follow this peculiar distribution. Although usually referred to as distinct entities, the clinical and histopathological presentation of lichen striatus in adults may be similar to those of adult blaschkitis. Read More

J Hematol Oncol 2017 Jan 5;10(1). Epub 2017 Jan 5.

Department of Bio-therapeutic, Institute of Basic Medicine, Chinese PLA General Hospital, No. 28 Fuxing Road, Beijing, 100853, China.

Background: Cholangiocarcinoma (CCA) is one of the most fatal malignant tumors with increasing incidence, mortality, and insensitivity to traditional chemo-radiotherapy and targeted therapy. Chimeric antigen receptor-modified T cell (CART) immunotherapy represents a novel strategy for the management of many malignancies. However, the potential of CART therapy in treating advanced unresectable/metastatic CCA is uncharted so far. Read More

J Cutan Pathol 2016 Nov 22;43(11):927-931. Epub 2016 Aug 22.

Department of Dermatology, Xijing Hospital, Fourth Military Medical University, Xian, China.

Background: Syringotropism is characterized by lymphocyte infiltration in the eccrine gland and is usually associated with various degrees of hyperplasia of eccrine gland cells. This phenomenon has been reported in rare cases of mycosis fungoides, which are also called as syringotropic mycosis fungoides.

Methods: We studied seven cases of lichen striatus associated with syringotropism and hyperplasia of eccrine gland cells, diagnosed at our dermatology department in the past 5 years. Read More

J Eur Acad Dermatol Venereol 2017 Apr 19;31(4):e200-e202. Epub 2016 Sep 19.

Department of Pediatric Dermatology, Hôpital Pellegrin-Enfants, Bordeaux, France.

J Am Acad Dermatol 2016 Sep;75(3):637-639

Department of Dermatology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.

J Clin Diagn Res 2016 Jun 1;10(6):EC19-22. Epub 2016 Jun 1.

Professor and Head, Department of Pathology, A J Institute of Medical Sciences , Kuntikana, Mangalore, Karnataka, India .

Introduction: Papulosquamous diseases are characterized by scaly papules and plaques with similar clinical picture which amounts to confusion and hence, a definitive histopathological diagnosis goes a long way in treatment of such diseases.

Aim: The aim of the study was to study the histomorphology of non-infectious, erythaematous, papulosquamous lesions of skin with clinicopathological correlation.

Materials And Methods: Skin biopsies from 150 clinically diagnosed/suspected non-infectious erythaematous, papulosquamous skin diseases were received in the Department of Pathology. Read More

Arch Dis Child 2016 Dec 18;101(12):1148. Epub 2016 Jul 18.

Pediatric Dermatology Unit, Ospedale "Dell'Angelo", Mestre (Venezia), Italy.

JAAD Case Rep 2016 Mar 3;2(2):102-4. Epub 2016 Mar 3.

University of Michigan Medical School, Ann Arbor, Michigan.

JAAD Case Rep 2015 Sep 28;1(5):254-6. Epub 2015 Jul 28.

Department of Dermatology, Texas Tech University Health Sciences Center, Lubbock, Texas.

Pediatr Dermatol 2016 May 2;33(3):301-6. Epub 2016 Mar 2.

Dermatology Department, American University of Beirut Medical Center, Beirut, Lebanon.

Background/objectives: In addition to several infectious and neoplastic cutaneous entities, plasmacytoid dendritic cells (pDCs) have been shown to be involved in the pathogenesis of multiple cutaneous inflammatory and autoimmune disorders, including those characterized histologically by an "interface dermatitis" pattern such as lupus or lichen planus (LP), but their role in lichen striatus (LS), which is also known to have this histologic inflammatory pattern, has never been studied. The objective of the study was to investigate the role of pDCs in LS.

Methods: Fifteen LS patients were found in our database and were immunohistochemically tested for pDC occurrence and activity using anti-blood-derived dendritic cell antigen-2 and anti-myxovirus resistance protein A (MxA) antibodies, respectively. Read More

Cutis 2016 Feb;97(2):86;120;122

Departments of Dermatology and Pathology, Geisinger Medical Center, Danville, Pennsylvania, USA.

Int J Dermatol 2016 Apr 19;55(4):e204-10. Epub 2016 Jan 19.

Department of Dermatology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.

Background: Lichen striatus (LS) and linear lichen planus (LLP) are separate uncommon disorders belonging to linear inflammatory dermatoses. The immunotyping of inflammatory cells has been investigated in LS and lichen planus (LP), but epidermal proliferation and differentiation have little been described in LS and LLP.

Methods: The clinical and pathological data of eight patients with LS and seven with LLP were retrospectively collected. Read More

Pediatr Dermatol 2016 Jan-Feb;33(1):95-6

Department of Dermatology, Duke University, Durham, North Carolina.

Clin Dermatol 2015 Nov-Dec;33(6):631-43. Epub 2015 Sep 12.

Department of Dermatology, Medical College of Wisconsin, 9200 W. Wisconsin Ave., Wauwatosa, WI 53226.

Lichenoid dermatoses, a group of inflammatory skin conditions with characteristic clinical and histopathologic findings, range from common to rare. Classic lichen planus typically presents as pruritic, polygonal, violaceous flat-topped papules and plaques; many variants in morphology and location also exist. Other lichenoid dermatoses share similar clinical presentations and histopathologic findings. Read More

Pediatr Dermatol 2016 Jan-Feb;33(1):e23-6. Epub 2015 Dec 8.

Department of Dermatology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.

Linear morphea and lichen striatus are distinct conditions that have been linked in only one previous case report. We describe two patients with facial lichen striatus preceding linear morphea at the same site. A possible pathogenic relationship is discussed. Read More

Indian Dermatol Online J 2015 Sep-Oct;6(5):333-5

Department of Dermatology, Adichunchanagiri Institute of Medical Sciences, Karnataka, India.

Lichen striatus with nail involvement is rare and is often unnoticed. Nail changes are often nonspecific but they are usually localized to one portion of the nail. Also single nail involvement and presence of skin lesions near the nail are often noticed. Read More

Int J Dermatol 2015 Nov;54(11):1255-60

Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, South Korea.

Background: Nail involvement in lichen striatus (LS) is rare and has not been documented extensively.

Objectives: This study describes the clinical and histological features, response to treatment, and follow-up in seven patients with nail LS.

Methods: We reviewed seven cases of nail LS between 2006 and 2012 at the Dermatology Department, Yeouido St Mary's Hospital, Seoul, South Korea. Read More

J Pak Med Assoc 2015 Sep;65(9):1011-3

Department of Pathology, Turgut Ozal University, Faculty of Medicine, Ankara, Turkey.

Lichen striatusis a rare linear papulardermatosis that primarily occurs in children. The lesions have a linear distribution following Blaschko's lines. Pityriasis lichenoides is an uncommon benign skin disorder with two major variants: acute and chronic. Read More

Pediatr Ann 2015 Aug;44(8):e194-8

A 3-year-old girl presented with a linear eruption on her leg for 2 months. She was otherwise healthy and well-appearing. Physical examination showed many small, erythematous, flat-topped papules coalescing into a linear erythematous plaque. Read More

Int J Dermatol 2016 Feb 31;55(2):173-6. Epub 2015 Jul 31.

Department of Dermatology, General University Hospital of Alicante, Alicante, Spain.

Background: Cutaneous lupus in childhood is usually associated with systemic lupus erythematosus (LE). Linear cutaneous LE (LCLE) is an unusual presentation mostly seen in children and young adults.

Methods: We report a rare case of cutaneous subacute LE with a segmentary pattern following the lines of Blaschko in an 18-month-old girl with a 2-month history of persistent, linear, asymptomatic, erythematous lesions along the right arm. Read More

Dermatol Clin 2015 Apr 14;33(2):197-205. Epub 2015 Feb 14.

Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami, Miami, 1600 Northwest 10th Avenue, FL 33136, USA. Electronic address:

This article reviews 6 nail disorders that, although easy to diagnose, are misdiagnosed frequently by dermatologists and general practitioners. Diagnostic clues are emphasized to familiarize readers with features that indicate the correct diagnosis. We focus on two common tumors (onychomatricoma and onychopapilloma), two rare genetic conditions that can be diagnosed owing to nail changes (Darier disease and nail patella syndrome), and two uncommon acquired disorders (the yellow nail syndrome and lichen striatus). Read More

Cutis 2014 Nov;94(5):E16-9

Wayne State University School of Medicine, 3901 Beaubien Blvd, Detroit, MI 48201, USA.

Lichen striatus (LS) is a relatively rare and self-limited linear dermatosis of unknown etiology. It primarily affects children, with more than 50% of cases occurring in patients aged 5 to 15 years. The case of a 2-year-old boy who presented for evaluation of a nonpruritic linear rash on the left side of the lower abdomen of 3 weeks' duration is discussed. Read More

Indian Dermatol Online J 2014 Oct;5(4):501-3

Departments of Experimental and Clinical Medicine, Institute of Dermatology, University of Udine, Udine, Italy.

Lichen striatus (LS) is an uncommon dermatosis of unknown etiology that presents as a continuous or interrupted linear band of pink, tan, red or skin-colored papules in a blaschkoid distribution. The lesions are generally solitary and unilateral, but unusual extensive cases with multiple and bilateral lesions have been also described. Albeit LS is typically an asymptomatic and self-limited dermatosis, it may cause a significant psychological distress in some patients, thus requiring an appropriate therapy. Read More

J Dermatol 2014 Dec 12;41(12):1133-4. Epub 2014 Nov 12.

Department of Dermatology, Fukushima Medical University, Fukushima, Japan.

J Cutan Pathol 2014 Dec 24;41(12):950-4. Epub 2014 Nov 24.

Department of Dermatology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.

Linear dermatoses are fascinating entities that likely reflect embryologically derived cutaneous mosaicism, even when they occur after childhood. Adult blaschkitis is a rare, relapsing inflammatory dermatitis that most often presents in middle age. It presents clinically as a pruritic eruption of linear papules, vesicles and plaques, and is most commonly found to have features of spongiotic dermatitis on pathology. Read More

J Dtsch Dermatol Ges 2014 Nov 28;12(11):1048-50. Epub 2014 Sep 28.

Department of Advanced Biomedical Sciences, Pathology Section, University of Naples Federico II, Naples, Italy.

Ann Dermatol 2014 Aug 31;26(4):505-9. Epub 2014 Jul 31.

Department of Dermatology, Hallym University Sacred Heart Hospital, Anyang, Korea.

Lichen nitidus (LN) is an uncommon, usually asymptomatic cutaneous eruption characterized by the presence of multiple, small, flesh-colored papules. The epidemiologic and pathophysiologic characteristics of LN have not yet been defined. Furthermore, LN has rarely been described in association with other cutaneous diseases. Read More

Cutan Ocul Toxicol 2015 18;34(2):171-2. Epub 2014 Jun 18.

Dermatology Clinic, Yenimahalle State Goverment Hospital , Ankara , Turkey .

Lichen striatus (LS) is an uncommon dermatosis characterised by a linear inflammatory papular eruption. It is frequently seen in children and rarely in adults. We present in this study a 49-year-old female patient who was diagnosed as LS, which occurs after a bite by bumblebee. Read More

Skinmed 2014 Mar-Apr;12(2):123-5

A 35-year-old man presented with asymptomatic eruption on both forearms and lower aspects of the legs for 6 months. The lesions first appeared on his inner aspects of the wrist, the dorsal surface of the hands, and legs and progressed to involve proximal aspects of the extremities. There was no significant past history. Read More

Int J Dermatol 2014 Jul 14;53(7):e366. Epub 2014 Feb 14.

Georgia Health Sciences University/University of Georgia Medical Partnership, Athens, GA, USA.

J Am Acad Dermatol 2014 Apr;70(4):e90-2

Dermatopathology Unit, San Gallicano Dermatological Institute, Rome, Italy. Electronic address:

Pediatr Dermatol 2014 Mar-Apr;31(2):e67-8. Epub 2014 Jan 24.

Beth Israel Medical Center, New York, NY; St. Luke's-Roosevelt Hospital Center, New York, NY.

Lichen striatus is a localized, eczematous disorder distributed along the lines of Blaschko, primarily affecting children. In the literature, lesions have been described as having an active phase of inflamed lesions for 6 to 12 months followed by flattening and persistent pigmentary alteration. We describe two girls who had prolonged active-phase lesions for 2. Read More

Case Rep Dermatol Med 2013 17;2013:261574. Epub 2013 Dec 17.

Department of Gynecology and Obstetrics, School of Medicine, Adnan Menderes University, 09100 Aydın, Turkey.

Inflammatory linear verrucous epidermal nevus (ILVEN) is a benign cutaneous hamartoma characterized by intensely erythematous, pruritic, and inflammatory papules that occur as linear bands along the lines of Blaschko. There is a considerable clinical and histological resemblance between ILVEN and linear psoriasis, lichen striatus, linear lichen planus, and invasion of epidermal nevus by psoriasis. The pathogenesis of ILVEN is unknown. Read More

Indian J Dermatol 2013 Nov;58(6):461-3

Department of Skin and VD, SCB Medical College, Cuttack, India.

Inflammatory linear verrucous epidermal nevus (ILVEN) is a pruritic, erythematous scaly epidermal nevus which follows a Blaschko's lines. Lichen striatus, linear Darier disease, linear porokeratosis, linear lichen planus, linear psoriasis, and the verrucous stage of incontinentia pigmenti may all have similar clinical presentations as the linear verrucous epidermal nevus. ILVEN can be distinguished from true nevoid psoriasis by pruritus and lack of response to antipsoriatic treatments. Read More

Eur J Dermatol 2013 Sep-Oct;23(5):671-6

Faculté de Médecine et Clinique Dermatologique, 1, place de l'Hôpital, 67091 Strasbourg Cedex, France.

Background: Blaschko-Linear Manifestations of Multifactorial Polygenic Diseases (BLMMPD) are rare. Their underlying pathogenesis is not known but genetic mosaicism is supposed to be involved.

Objectives: To describe a series of patients with BLMMPD and to establish a meaningful classification of these manifestations. Read More

Dermatol Ther 2014 May-Jun;27(3):144-7. Epub 2013 Oct 1.

Department of Dermatology and Venerology, University Hospital, Comenius University School of Medicine, Bratislava, Slovak Republic.

Linear porokeratosis (LP) is a rare clinical porokeratosis variant, which typically presents at birth, but can also develop in adulthood. Differential diagnosis includes linear lichen planus, lichen striatus, linear verrucous epidermal nevus, incontinentia pigmenti and linear Darier's disease. An LP lesion has an increased risk of transformation into a squamous cell carcinoma or basal cell carcinoma. Read More

Am J Dermatopathol 2014 Jan;36(1):e1-4

*Dermatopathology Section, Department of Dermatology, Boston University School of Medicine, Boston, MA; and †South Shore Skin Center, Plymouth, MA.

Lichen aureus (LA) presents an inflammatory infiltrate with a lichenoid pattern, which mainly localizes to the superficial dermis, and it is admixed with extravasated erythrocytes. We present the case of a 12-year-old male who had a 1.3-cm golden-brown-color patch on the right upper back for 2 weeks. Read More

Indian J Dermatol Venereol Leprol 2013 May-Jun;79(3):349-59

Department of Dermatology and Dermato Pathology, P D Hinduja Hospital, Mumbai, Maharashtra, India.

Interface dermatitis includes diseases in which the primary pathology involves the dermo-epidermal junction. The salient histological findings include basal cell vacuolization, apoptotic keratinocytes (colloid or Civatte bodies), and obscuring of the dermo-epidermal junction by inflammatory cells. Secondary changes of the epidermis and papillary dermis along with type, distribution and density of inflammatory cells are used for the differential diagnoses of the various diseases that exhibit interface changes. Read More

Indian J Dermatol Venereol Leprol 2013 Mar-Apr;79(2):251-2

N Engl J Med 2012 Dec;367(25):2427

McGill University, Montreal, QC, Canada.

Pediatr Dermatol 2013 May-Jun;30(3):364-6. Epub 2012 Sep 7.

Department of Dermatology, School of Medicine, Johns Hopkins University, Baltimore, MD21287, USA.

We report seven patients with facial lichen striatus along the lines of Blaschko who presented to our pediatric dermatology unit between 2003 and 2009. The mean age of diagnosis was 4.6 years (range 2. Read More

J Drugs Dermatol 2012 Jul;11(7):872-5

Department of Dermatology, University of Wisconsin-Madison, Madison, WI 53715, USA.

Lichen striatus (LS) is an uncommon linear dermatosis that is primarily seen in children from 4 months to 15 years of age. While some of these eruptions are asymptomatic, others can be quite pruritic. In darker-skinned individuals, post-inflammatory hypopigmentation can be significant and may provide a cause for concern for the patients and/or their parents. Read More

Australas J Dermatol 2013 Feb 4;54(1):41-2. Epub 2012 Jun 4.

Department of Dermatology and STD, University College of Medical Sciences, University of Delhi Associated Guru Teg Bahadur Hospital, Delhi, India.

Cutaneous mosaicism has always been an intriguing subject. A 15-year-old boy presented to us with a unilateral band of lesions of pityriasis rosea and lichen striatus. The case is discussed in the light of the concept of genetic mosaicism. Read More

Int J Dermatol 2012 Apr;51(4):369-71

Department of Dermatology, Valley Hospital Medical Center, Touro University College of Osteopathic Medicine, Las Vegas, NV 89106, USA.

Ugeskr Laeger 2012 Mar;174(10):652-3

Det Sundhedsvidenskabelige Fakultet, Syddansk Universitet, Campusvej 55, 5230 Odense, Denmark.

A six year-old boy was referred with an asymptomatic linear rash on his left arm and a nail involvement of a fingernail on his left hand. Multiple small erythematous papules coalescing into a linear band extending to the thumb with nail abnormality were noted on the left arm. A diagnosis of lichen striatus was established clinically. Read More

Ann Dermatol 2012 Feb 2;24(1):87-9. Epub 2012 Feb 2.

Department of Dermatology, School of Medicine, Pusan National University, Busan, Korea.

Lichens striatus (LS) is an acquired, self-limiting inflammatory dermatosis that follows the lines of Blaschko. The etiology of the eruption is unknown, but several theories have been proposed with focus on environmental factors, viral infection, cutaneous injury, hypersensitivity, and genetic predisposition. We describe a 19-year-old woman who developed a unilateral linear eruption 17 months after allogenic peripheral blood stem cell transplantation. Read More

Clin Exp Dermatol 2012 Jul 2;37(5):570-2. Epub 2012 Feb 2.

J Dermatol 2012 Sep 14;39(9):802-4. Epub 2011 Dec 14.