Bull Exp Biol Med 2022 Apr 2;172(6):734-737. Epub 2022 May 2.
Pirogov Russian National Research Medical University, Ministry of the Health of the Russian Federation, Moscow, Russia.
Lichen sclerosus of the vulva is a common, but poorly studied disease. We assessed the level of transcriptional activity of APAF1, BAX, BCL2, BIRC5, CCND1, DAPK1, MCL1, and MYC genes encoding products that control apoptosis in the samples of tissues affected by vulvar lichen sclerosus and adjacent control tissues (n=24). Analysis of transcriptional activity was performed by real-time PCR using specific primers and SYBR Green intercalating dye. Read More