9,374 results match your criteria Lichen Planus


Systematic review with meta-analysis: extrahepatic manifestations in chronic hepatitis C virus-infected patients in East Asia.

Aliment Pharmacol Ther 2019 Feb 13. Epub 2019 Feb 13.

Washington, District of Columbia.

Background: Although the prevalence of extrahepatic manifestations of chronic hepatitis C virus (HCV) infection has been reported from Western countries, their prevalence in East Asian countries is not well known.

Aim: To perform a systematic review to quantify the prevalence of selected extrahepatic manifestations of HCV among patients from East Asia.

Methods: Medline, CINAHL, EMBASE, Cochrane and country-specific databases were reviewed according to standard guidelines for meta-analyses. Read More

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http://dx.doi.org/10.1111/apt.15131DOI Listing
February 2019

Oral lichen planus and lichen planopilaris complicated with thymoma.

J Dermatol 2019 Feb 13. Epub 2019 Feb 13.

Department of Dermatology, Shiga University of Medical Science, Otsu, Japan.

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http://dx.doi.org/10.1111/1346-8138.14812DOI Listing
February 2019

Statin-related Lichenoid Dermatosis: An Uncommon Adverse Reaction to a Common Treatment.

Eur J Case Rep Intern Med 2018 25;5(5):000844. Epub 2018 May 25.

Hypertension and Dyslipidemia Outpatient Clinic, Medicine 4, Santa Marta's Hospital, CHLC, Lisbon, Portugal.

3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) are generally safe and well-tolerated drugs that are extensively used for the primary and secondary prevention of atherosclerotic cardiovascular events. Muscle and liver adverse reactions are the best recognized, while cutaneous side effects are exceedingly rare. We present the case of a 65-year-old woman with severe hypercholesterolemia, who developed generalized erythematous cutaneous lesions with pruritus, resembling lichen planus, months after starting treatment with simvastatin. Read More

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http://dx.doi.org/10.12890/2018_000844DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346926PMC

Pediatric lichen nitidus: A single-center experience.

Pediatr Dermatol 2019 Feb 11. Epub 2019 Feb 11.

Department of Pathology, Dr. Behcet Uz Children's Research and Training Hospital, Izmir, Turkey.

Objective: Lichen nitidus (LN) is an uncommon inflammatory skin eruption. The present study aims to describe a case series of children with LN seen at a tertiary-care health center.

Methods: Retrospective study of 17 children with biopsy-proven LN between January 2007 and March 2017. Read More

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http://doi.wiley.com/10.1111/pde.13749
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http://dx.doi.org/10.1111/pde.13749DOI Listing
February 2019
1 Read

Expression of Cluster of Differentiation 1a-Positive Langerhans Cells in Oral Lichen Planus.

Indian J Dermatol 2019 Jan-Feb;64(1):41-46

Department of Oral Pathology, Madha Dental College and Hospital, Chennai, Tamil Nadu, India.

Background/purpose: Lichen planus is a T-cell-mediated mucocutaneous disorder characterized histopathologically by a band of chronic inflammatory cells in the subepithelial zone and degeneration of basal layer. The present study was aimed to evaluate the distribution and quantitative assessment of cluster of differentiation 1a (CD1a)-positive Langerhans cells (LCs) in oral lichen planus (OLP), thus to determine the role of LCs pertaining to the changes occurring in OLP.

Materials And Methods: Five cases of normal oral mucosa and 20 cases of OLP were immunostained with CD1a antibody; the positive cells were counted manually in the photomicrographs and statistically analyzed using -test, Mann-Whitney test, and Wilcoxon signed-rank test. Read More

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http://dx.doi.org/10.4103/ijd.IJD_350_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340233PMC
February 2019

Foreign body gingivitis: An uncommon iatrogenic simulant of oral lichenoid mucositis.

JAAD Case Rep 2019 Feb 31;5(2):173-175. Epub 2019 Jan 31.

Department of Dermatology, University of California, San Francisco, California.

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http://dx.doi.org/10.1016/j.jdcr.2018.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357549PMC
February 2019

Role of mammary serine protease inhibitor on the inflammatory response in oral lichen planus.

Oral Dis 2019 Feb 9. Epub 2019 Feb 9.

Shanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, China.

Objectives: Oral lichen planus (OLP) is a chronic inflammatory condition with an unclear pathological mechanism. IκB kinase α (IKKα)-regulated mammary serine protease inhibitor (MASPIN) has been shown to mediate inflammation, particularly in cancers. Here, we explored the expression of MASPIN in OLP and its role in the inflammatory response. Read More

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http://doi.wiley.com/10.1111/odi.13054
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http://dx.doi.org/10.1111/odi.13054DOI Listing
February 2019
2 Reads

Serum-based metabolomics characterization of patients with reticular oral lichen planus.

Arch Oral Biol 2019 Jan 30;99:183-189. Epub 2019 Jan 30.

First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin 150040, PR China. Electronic address:

Objective: Oral lichen planus (OLP) is a chronic inflammatory mucosal lesion and systemic disease. In OLP, reticular type is the most common presentation of the disease. However, little is known about it. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2019.01.019DOI Listing
January 2019
1 Read

[Gingival squamous cell carcinoma diagnosed on the occasion of osteonecrosis of the jaw in a patient with chronic GVHD].

Rinsho Ketsueki 2019 ;60(1):22-27

Department of Hematology, Atomic Bomb Disease and Hibakusha Medicine Unit, Atomic Bomb Disease Institute, Nagasaki University.

A 44-year-old male was diagnosed with acute myeloid leukemia with a complex karyotype. He underwent bone marrow transplantation using an HLA 6/6 antigen-matched sibling donor, but developed chronic graft-versus-host disease (cGVHD) with skin erythema and oral and esophageal lichen planus changes. Treatment with a combination of prednisolone and cyclosporine was initiated on day 646 after transplantation, but oral symptoms persisted. Read More

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http://dx.doi.org/10.11406/rinketsu.60.22DOI Listing
January 2019
2 Reads

Invited Review: Association of nitric oxide with oral lichen planus.

J Oral Pathol Med 2019 Feb 6. Epub 2019 Feb 6.

Department of Oral & Maxillofacial Surgery, Queen Alexandra Hospital, Portsmouth, UK.

Background: The small signalling molecule nitric oxide (NO) has been postulated to have a mediator role in the pathogenesis of several diseases including oral lichen planus (OLP). This systematic review aimed to quantify the existing literature and assess the association of NO and OLP.

Methods: The focused question being addressed was "Is there an association between nitric oxide and OLP?" PubMed, EMBASE, Scopus, and Web of Science, and grey literature from January 1990 to August 2018 were searched. Read More

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http://dx.doi.org/10.1111/jop.12837DOI Listing
February 2019

The Gingival Oral Lichen Planus: A Periodontal-Oral Medicine Approach.

Case Rep Dent 2019 6;2019:4659134. Epub 2019 Jan 6.

NK Perio & Implants, Perth 6172 Western Australia, Australia.

We present a case of a 77-year-old female who suffered from oral lichen planus (OLP) involving her gingiva and bilateral buccal mucosa for over 6 months. We showed that oral hygiene measures and conventional periodontal treatment and strict maintenance were sufficient to control the gingival involvement of OLP. The mechanism of OLP is complex and not yet fully understood. Read More

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http://dx.doi.org/10.1155/2019/4659134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339732PMC
January 2019

Mucous membrane pemphigoid of the oral lichen type: a retrospective analysis of 16 cases.

J Eur Acad Dermatol Venereol 2019 Feb 5. Epub 2019 Feb 5.

Department of Dermatology, Inselspital - Bern University Hospital, CH-3010, Bern, Switzerland.

Mucous membrane pemphigoid (MMP) and oral lichen planus (OLP) may be difficult to distinguish. We describe the characteristics of a retrospective series of patients with MMP with isolated oral involvement who presented clinical features indistinguishable from OLP. Proper classification of these MMP cases critically depended on the performance of direct immunofluorescence (DIF) microscopy studies. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jdv.15473
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http://dx.doi.org/10.1111/jdv.15473DOI Listing
February 2019
4 Reads

Lichen planus pigmentosus: a case series with different ethnical, clinical and dermoscopic features.

G Ital Dermatol Venereol 2019 Feb 4. Epub 2019 Feb 4.

Division of Dermatology, Department of Specialistic, Diagnostic and Experimental Medicine, University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.23736/S0392-0488.19.06242-4DOI Listing
February 2019

Decreased left atrial strain parameters are associated with prolonged total atrial conduction time in lichen planus.

Interv Med Appl Sci 2018 Sep;10(3):150-156

Faculty of Medicine, Department of Cardiology, Recep Tayyip Erdoğan University, Rize, Turkey.

Background: Lichen planus (LP) carries the increased risk of cardiovascular events as it is a chronic inflammatory disease. This study aimed at determining the relationship between total atrial conduction time (TACT), P-wave dispersion, and the left atrium (LA) global strain in the patients with LP.

Methods: Forty people as a control group and 40 patients with LP were included in this study. Read More

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http://dx.doi.org/10.1556/1646.10.2018.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343578PMC
September 2018

Artemisinin and its derivatives: a potential therapeutic approach for oral lichen planus.

Inflamm Res 2019 Feb 1. Epub 2019 Feb 1.

The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, 430079, People's Republic of China.

Background: Oral lichen planus (OLP) is a common T-cell-mediated oral mucosal disease, whose pathogenesis mainly includes antigen-specific and non-specific mechanisms. As a refractory chronic inflammatory disease, there is still no curable management for OLP till now.

Findings: Artemisinins are a family of compounds that are widely used as frontline treatment for malaria worldwide. Read More

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http://link.springer.com/10.1007/s00011-019-01216-0
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http://dx.doi.org/10.1007/s00011-019-01216-0DOI Listing
February 2019
6 Reads

Direct immunofluorescence findings in cicatricial alopecia: A retrospective study of 155 cases.

Indian J Pathol Microbiol 2019 Jan-Mar;62(1):103-106

Department of Dermatology, Maulana Azad Medical College, New Delhi, India.

Objectives: To study the direct immunofluorescence (DIF) in cicatricial alopecia (CA) patients.

Materials And Methods: Approximately, 155 skin biopsies from CA patients examined over 7 years (2009-2015). Special stains and Hematoxylin and Eosin were performed, and final histopathological diagnosis was made. Read More

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http://dx.doi.org/10.4103/IJPM.IJPM_428_18DOI Listing
February 2019
2 Reads

Impressive oral lichen planus progression to invasive squamous cell carcinoma in a three months lapse.

Oral Oncol 2019 Jan 28. Epub 2019 Jan 28.

Dermatology Clinic - Department of Medical Sciences and Public Health, University of Cagliari, Via Ospedale 54, 09124 Cagliari, Italy.

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http://dx.doi.org/10.1016/j.oraloncology.2018.11.029DOI Listing
January 2019

The reciprocal association between diabetes mellitus and erosive oral lichen planus.

Oral Dis 2019 Jan 30. Epub 2019 Jan 30.

State Key Laboratory of Oral Diseases, Department of Oral Medicine, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, P.R. China.

We read with interest the article by Otero Rey E. M. and colleagues that was recently published in Oral Diseases (Otero Rey E. Read More

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http://dx.doi.org/10.1111/odi.13050DOI Listing
January 2019

Ulcerated Lesions of the Oral Mucosa: Clinical and Histologic Review.

Head Neck Pathol 2019 Jan 31. Epub 2019 Jan 31.

Department of Diagnostic and Biomedical Sciences, University of Texas at Houston Health Science Center School of Dentistry, Houston, TX, USA.

Ulcerated lesions of the oral cavity have many underlying etiologic factors, most commonly infection, immune related, traumatic, or neoplastic. A detailed patient history is critical in assessing ulcerative oral lesions and should include a complete medical and medication history; whether an inciting or triggering trauma, condition, or medication can be identified; the length of time the lesion has been present; the frequency of episodes in recurrent cases; the presence or absence of pain; and the growth of the lesion over time. For multiple or recurrent lesions the presence or history of ulcers on the skin, genital areas, or eyes should be evaluated along with any accompanying systemic symptoms such as fever, arthritis, or other signs of underlying systemic disease. Read More

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http://dx.doi.org/10.1007/s12105-018-0981-8DOI Listing
January 2019
1 Read

[Research progress of dental implant in patients with oral lichen planus].

Authors:
L Fu L A C Y Li Y M Zhou

Zhonghua Kou Qiang Yi Xue Za Zhi 2019 Feb;54(2):135-137

Department of Dental Implantology, School of Stomatology, Jilin University, Changchun 130021, China.

In recent years, the range of indications for dental implants has undergone many modifications and has been widened. In the past, oral lichen planus was regarded as contraindication for the placement of implants. According to recent literature, some patients with oral lichen planus have been selected for dental implantology, indicating comparable implant survival rate to patients without oral lichen planus. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1002-0098.2019.02.011DOI Listing
February 2019

Should We Always Biopsy in Clinically Evident Lichen Sclerosus?

J Low Genit Tract Dis 2019 Jan 25. Epub 2019 Jan 25.

Department of Dermatology, South Infirmary Victoria University Hospital, Cork, Ireland.

The aims of the study were to review cases of clinically diagnosed lichen sclerosus (LS) and to compare the histological features found on biopsy to clinical features seen on examination.

Methods: A retrospective chart review was undertaken of patients attending a specialist vulval service between 2013 and 2015 with a clinical diagnosis of LS. Patients in whom there was clinical diagnostic uncertainty or those with features of lichen planus or lichen planus/LS overlap were excluded. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000457DOI Listing
January 2019

Nail lichen planus.

J Am Acad Dermatol 2019 Jan 22. Epub 2019 Jan 22.

St. John's Institute of Dermatology, Guy's Hospital, London SE1 9RT, UK.

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http://dx.doi.org/10.1016/j.jaad.2019.01.023DOI Listing
January 2019

Letter to the Editor: Nail Lichen Planus: A True Nail Emergency.

Authors:
Shari R Lipner

J Am Acad Dermatol 2019 Jan 22. Epub 2019 Jan 22.

Department of Dermatology, Weill Cornell Medicine, NY, NY 10021. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2018.11.065DOI Listing
January 2019

Clinical Photography: Attitudes among Dental Students in Two Dental Institutions.

Eur J Dent Educ 2019 Jan 25. Epub 2019 Jan 25.

Department of Community Dentistry, The Hebrew University - Hadassah School of Dental Medicine, Jerusalem, Israel.

Introduction: Clinical photography is an important tool in teaching, clinical practice and academia especially for mucosal pathologies. Our aim was to examine differences in attitude toward clinical photography for mucosal pathologies among students.

Methods: Questionnaires about clinical photography were completed by students in dental teaching hospitals in Birmingham (U. Read More

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http://dx.doi.org/10.1111/eje.12424DOI Listing
January 2019
1 Read

Role of modern imaging techniques for the diagnosis of lichen planus.

Exp Ther Med 2019 Feb 16;17(2):1052-1060. Epub 2018 Nov 16.

Department of Physiology, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.

Lichen planus (LP) is a chronic inflammatory skin disease that can sometimes affect mucosal surfaces, with unknown pathogenesis, even though it appears to be an autoimmune disease. The diagnosis of lichen planus is usually based on histopathological examination of the lesions. Nowadays, the classical invasive diagnostic methods are replaced by modern non-invasive techniques. Read More

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http://www.spandidos-publications.com/10.3892/etm.2018.6974
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http://dx.doi.org/10.3892/etm.2018.6974DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327670PMC
February 2019
5 Reads
0.941 Impact Factor

Potential pathogenic mechanisms involved in the association between lichen planus and hepatitis C virus infection.

Exp Ther Med 2019 Feb 16;17(2):1045-1051. Epub 2018 Nov 16.

Department of Microbiology, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Lichen planus (LP) is an immune-mediated inflammatory disease that particularly affects the skin and mucous membranes. Its etiology remains elusive, however some trigger factors, including viral or bacterial antigens, drugs and metals, have been postulated. There is a higher prevalence of hepatitis C virus (HCV) infection among patients with LP, with some geographical variations. Read More

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http://dx.doi.org/10.3892/etm.2018.6987DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327648PMC
February 2019

Seven-year itch: a perplexing case of lichen planus-lupus erythematosus overlap syndrome.

Dermatol Online J 2018 Sep 15;24(9). Epub 2018 Sep 15.

Department of Dermatology, SUNY Downstate Medical Center, Brooklyn, New York.

Lichen planus-lupus erythematosus overlap syndrome is a rare disorder characterized by clinical and histopathological features of both lichen planus (LP) and lupus erythematosus (LE). Cutaneous lesions commonly affect the distal arms, legs, face, and trunk and these plaques are often large, scaly, painful, and atrophic, often exhibiting hypopigmentation or a red to blue-violet color. We report a case of LP-LE overlap syndrome diagnosed in a man previously believed to have atypical lichen planus who presented with an exacerbation of exuberant pruritic erythematous scaly plaques. Read More

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September 2018
1 Read

Recurrent retroauricular cystic nodules: lichen planus follicularis tumidus.

Dermatol Online J 2018 Oct 15;24(10). Epub 2018 Oct 15.

Department of Pathology and Laboratory Medicine, University of California Davis, Sacramento, California Department of Dermatology, University of California Davis, Sacramento, California.

Lichen planus follicularis tumidus (LPFT) is a rare subtype of lichen planus (LP) that has been most commonly described in middle-aged women. LPFT clinically manifests as recurrent cystic follicular nodules that preferentially involve the retroauricular area; concurrent classic LP lesions on the extremities and mucosal surfaces may also be present. Histologically, LPFT demonstrates epithelial-lined follicular cysts filled with orthokeratotic keratin surrounded by a dense lichenoid infiltrate. Read More

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October 2018

Lichen planus pigmentosus.

Dermatol Online J 2018 Dec 15;24(12). Epub 2018 Dec 15.

The Ronald O. Perelman Department of Dermatology, New York University Langone Medical Center, New York, New York.

Lichen planus pigmentosus (LPP) is an uncommon variant of lichen planus of unclear etiology that predominantly affects patients of skin types III to VI. We report a case of LPP of two years duration in a 67-year-old man involving upper extremities, chest, abdomen, and upper back. Read More

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December 2018
5 Reads

Association of OLP and thyroid disorder: Case report and review of literature.

J Stomatol Oral Maxillofac Surg 2019 Jan 21. Epub 2019 Jan 21.

Department of Oral Medicine, Radiology, Faculty of Dental Sciences, Ramaiah University of Applied Sciences, India.

Oral lichen planus is a chronic T cell mediated inflammatory condition with multifactorial etiology. Being autoimmune mediated condition, it has been associated with other autoimmune disorders. This case report discusses the possible presentation of oral lichen planus in hypothyroid patients as a marker of severity of the thyroid deficient status and the possible pathogenetic link between both the conditions. Read More

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http://dx.doi.org/10.1016/j.jormas.2019.01.008DOI Listing
January 2019

Assessment of Interleukin-18 gene polymorphism and serum levels in oral lichen planus in an Indian population.

J Oral Pathol Med 2019 Jan 22. Epub 2019 Jan 22.

Pediatrics Research and Genetics Laboratory, Department of Pediatrics, Maulana Azad Medical College, New Delhi, India.

Background: Oral lichen planus (OLP) is a chronic, inflammatory disease with uncertain etiology. The aim of this study was to assess Interleukin-18 (IL-18) gene polymorphism and serum levels in OLP cases of Indian origin and to compare them with a control population of similar background.

Methods: The assessment of single-nucleotide polymorphisms (SNPs) of IL-18 gene at promoter regions -137(G/C) and -607(C/A) was done in 70 OLP cases and 70 healthy controls using sequence-specific primer-polymerase chain reaction (SSP-PCR). Read More

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http://dx.doi.org/10.1111/jop.12830DOI Listing
January 2019

miR‑122 and miR‑199 synergistically promote autophagy in oral lichen planus by targeting the Akt/mTOR pathway.

Int J Mol Med 2019 Mar 21;43(3):1373-1381. Epub 2019 Jan 21.

Department of Geriatrics, Ningbo No. 2 Hospital, Ningbo, Zhejiang 315010, P.R. China.

The aim of the present study was to characterize the roles of two microRNAs (miRNAs), miR‑122 and miR‑199, in oral lichen planus (OLP). miRNA microarray analysis was performed to detect potential miRNAs involved in OLP, while in‑silicon analysis, reverse transcription‑quantitative polymerase chain reaction (RT‑qPCR), western blot and immunohistochemistry (IHC) analyses were utilized to explore the molecular mechanisms underlying the roles of miR‑199 and miR‑122 in OLP. The results from the microarray and RT‑qPCR analyses demonstrated that the expression levels of miR‑122 and miR‑199 were significantly decreased in the peripheral blood mononuclear cells (PBMCs) collected from the OLP group compared with the control group. Read More

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http://dx.doi.org/10.3892/ijmm.2019.4068DOI Listing

Modified phenol peels for treatment-refractory hyperpigmentation of lichen planus pigmentosus: A retrospective clinico-dermoscopic analysis.

J Cosmet Dermatol 2019 Jan 20. Epub 2019 Jan 20.

Department of Dermatology, Purnam Skin Clinic, Kolkata, India.

Background: Lichen Planus Pigmentosus (LPP), a disorder with stubborn treatment-refractory hyperpigmentation predominantly affects the darker skin. Deep dermal pigmentary incontinence of LPP renders the condition treatment-refractory.

Objectives: Lack of a consistently effective depigmenting treatment protocol of inactive LPP mandates exploration of novel approaches. Read More

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http://doi.wiley.com/10.1111/jocd.12862
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http://dx.doi.org/10.1111/jocd.12862DOI Listing
January 2019
11 Reads

Isolated lichen planus of lip: Diagnosis and treatment monitoring using dermoscopy.

Clin Case Rep 2019 Jan 22;7(1):146-148. Epub 2018 Nov 22.

Department of Dermatology College of Medical Sciences Bharatpur Nepal.

Lichen planus (LP) of lip has chances of malignant transformation as it may be exposed to external trauma, smoking, and ultraviolet light. This case highlights the use of dermoscope as a quick noninvasive tool for the diagnosis of LP of lip and monitoring the response to treatment. Read More

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http://dx.doi.org/10.1002/ccr3.1933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333123PMC
January 2019
1 Read

Role of miR-155 in immune regulation and its relevance in oral lichen planus.

Exp Ther Med 2019 Jan 27;17(1):575-586. Epub 2018 Nov 27.

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Oral Medicine of West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan 610041, P.R. China.

Oral lichen planus (OLP) is a chronic mucosal inflammatory disease. The World Health Organization has described it as a potentially malignant condition. The pathogenesis of OLP remains to be fully elucidated, but extensive evidence suggests that immunologic and inflammatory factors have important roles. Read More

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http://www.spandidos-publications.com/10.3892/etm.2018.7019
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http://dx.doi.org/10.3892/etm.2018.7019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307429PMC
January 2019
3 Reads

Human papillomavirus in premalignant oral lesions: No evidence of association in a Spanish cohort.

PLoS One 2019 16;14(1):e0210070. Epub 2019 Jan 16.

Cancer Epidemiology Research Program, IDIBELL, Catalan Institute of Oncology (ICO), L'Hospitalet de Llobregat, Barcelona, Spain.

Background: Human papillomavirus (HPV) is the cause of a fraction of head and neck squamous cell carcinoma. Although this relation is well-known, it is still not clear the role of HPV in premalignant oral lesions such as oral lichen planus (OLP) and dysplasia. We aimed to evaluate the HPV-DNA prevalence and type distribution in a set of oral biopsies obtained from patients diagnosed with OLP and dysplasia, as well as the role of HPV in these lesions. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0210070PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335078PMC
January 2019
3 Reads

Hypertrophic Lichen Planus Mimicking Verrucous Lupus Erythematosus.

Cureus 2018 Nov 6;10(11):e3555. Epub 2018 Nov 6.

Dermatologist, San Diego Family Dermatology, San Diego, USA.

Lichen planus is an inflammatory skin condition that can affect the hair, mucous membranes, nails, and skin. Cutaneous lichen planus typically presents as papules that are planar, polygonal, pruritic, and purple. Subtypes of lichen planus include actinic, annular, atrophic, eruptive, follicular, hypertrophic, inverse, linear, palmoplantar, pemphigoides, pigmentosus, ulcerative, vesiculobullous, and vulvovaginal. Read More

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http://dx.doi.org/10.7759/cureus.3555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324858PMC
November 2018
2 Reads

Evaluation of serum and salivary interferon-γ levels in patients with oral lichen planus: a systematic review and meta-analysis of case-control studies.

Oral Surg Oral Med Oral Pathol Oral Radiol 2019 Mar 24;127(3):210-217. Epub 2018 Nov 24.

Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran. Electronic address:

Objective: Cytokines have regulatory and leading roles in the immunopathogenesis of oral lichen planus (OLP). Here, we present the findings of a meta-analysis that evaluated serum and salivary interferon-γ (IFN-γ) levels in patients with OLP compared with those in controls and the correlation of this cytokine with the progression of OLP.

Study Design: Four databases-PubMed, Web of Science, Scopus, and Cochrane Library-were searched, from their start dates to November 2017, for reports in all languages on the effect of OLP on salivary and serum IFN-γ. Read More

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http://dx.doi.org/10.1016/j.oooo.2018.11.006DOI Listing

Low dose thalidomide monotherapy for the treatment of recalcitrant erosive lichen planus.

Dermatol Ther 2019 Jan 14:e12824. Epub 2019 Jan 14.

Department of Pathology, Dr RML Hospital & PGIMER, New Delhi, India.

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http://doi.wiley.com/10.1111/dth.12824
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http://dx.doi.org/10.1111/dth.12824DOI Listing
January 2019
2 Reads

Downregulated miR-27b promotes keratinocyte proliferation by targeting PLK2 in oral lichen planus.

J Oral Pathol Med 2019 Jan 14. Epub 2019 Jan 14.

Department of Oral Medicine, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, 639 Zhi Zao Ju Road, Shanghai, 200011, China.

Background: MicroRNA-27b (miR-27b) was recently found to be significantly downregulated in oral lichen planus (OLP). However, evidence of the function of miR-27b in OLP remains limited.

Methods: Initially, miR-27b expression in OLP was verified using the quantitative real-time polymerase chain reaction (qRT-PCR). Read More

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http://dx.doi.org/10.1111/jop.12826DOI Listing
January 2019
1 Read

Subclinical atherosclerosis and cardiovascular markers in patients with lichen planus: A case-control study.

Indian J Dermatol Venereol Leprol 2019 Mar-Apr;85(2):138-144

Department of Dermatology, Skin Research Center, Shohada-e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: Lichen planus is an idiopathic and chronic inflammatory disease that affects the skin and the mucous membranes, and has been associated with an increased risk for cardiovascular diseases. Hyperhomocysteinemia has been regarded as a risk factor for atherosclerosis and cardiovascular diseases. Increased plasma fibrinogen levels are also associated with increased risk of myocardial infarction. Read More

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http://dx.doi.org/10.4103/ijdvl.IJDVL_1080_16DOI Listing
January 2019
5 Reads

Erythema dyschromicum perstans: A case report and systematic review of histologic presentation and treatment.

Int J Womens Dermatol 2018 Dec 27;4(4):216-222. Epub 2018 Sep 27.

Department of Dermatology, Duke University Medical Center, Durham, North Carolina.

Objective: Erythema dyschromicum perstans (EDP) can be difficult to diagnose and treat; therefore, we reviewed the literature to assess whether histology can be used to differentiate lichen planus pigmentosus (LPP) from EDP and determine which treatments are the most effective for EDP. We also present a case of a patient who was treated successfully with narrow-band ultraviolet B (NB-UVB).

Methods: A systematic review in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses was conducted up to July 2017 using four databases. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S23526475183003
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http://dx.doi.org/10.1016/j.ijwd.2018.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322153PMC
December 2018
9 Reads

Syphilis cornee mimicking lichen planus clinically and histologically.

Indian J Sex Transm Dis AIDS 2018 Jul-Dec;39(2):130-132

Department of Dermatology and Venereology, Government Medical College, Thrissur, Kerala, India.

Palmoplantar lesions of secondary syphilis are often termed "syphilis cornee." A 32-year-old male presented with itchy lichenoid papules on both soles and left palm associated with grayish white papules on the buccal mucosa and glans penis. Initial clinical diagnosis of palmoplantar lichen planus with mucosal involvement was supported by the histopathological finding of interface dermatitis. Read More

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http://dx.doi.org/10.4103/ijstd.IJSTD_15_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298153PMC
January 2019
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A systematic review and meta-analysis study of salivary and serum interleukin-8 levels in oral lichen planus.

Postepy Dermatol Alergol 2018 Dec 13;35(6):599-604. Epub 2018 Nov 13.

Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Introduction: Interleukin-8 (IL-8) is an important mediator of the host response to injury and inflammation that the clinical severity of oral lichen planus (OLP) is associated with elevated serum IL-8 levels.

Aim: To evaluate serum and salivary IL-8 levels of the OLP patients compared with the healthy controls and measurement of IL-8 level in which sample is more valuable.

Material And Methods: Five databases including PubMed/Medline, Web of Science, Science Direct, Cochrane Library and Scopus were searched for the evaluation of serum and salivary IL-8 levels of the OLP patients compared with the healthy controls in the English abstract. Read More

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http://dx.doi.org/10.5114/ada.2018.77611DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320489PMC
December 2018

Could colchicine represent a new therapeutic approach for lichen planus pigmentosus?

Dermatol Ther 2019 Jan 7:e12809. Epub 2019 Jan 7.

Dissal Section of Dermatology, Policlinico San Martino Hospital, University of Genova, Genova, Italy.

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http://dx.doi.org/10.1111/dth.12809DOI Listing
January 2019
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Curcumin, a turmeric extract, for oral lichen planus: A systematic review.

Oral Dis 2019 Jan 7. Epub 2019 Jan 7.

University of Connecticut School Dental Medicine, Farmington, Connecticut.

Objective: Conduct a PROSPERO registered (CRD42018105227) systematic review of the efficacy of curcumin in the treatment of oral lichen planus (OLP).

Data Sources: Medline from the earliest possible date to the present (December 18, 2018) using the terms "turmeric" OR "curcumin" OR "curcuma" AND "oral lichen planus".

Study Selection And Data Extraction: Studies assessing patient outcomes in OLP. Read More

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http://doi.wiley.com/10.1111/odi.13034
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http://dx.doi.org/10.1111/odi.13034DOI Listing
January 2019
14 Reads

'Nasal flossing': A case report of nasopharyngeal stenosis due to severe erosive lichen planus and a novel therapeutic intervention.

Int J Surg Case Rep 2019 13;54:99-102. Epub 2018 Nov 13.

NHS GGC, Professor of Maxillofacial Surgery, University of Bradford, United Kingdom.

Introduction: We describe a case of severe erosive oral lichen planus that led to nasopharyngeal stenosis. This is a rare clinical presentation that was ultimately, successfully treated by surgery combined with post-operative 'nasal flossing': a novel therapeutic intervention.

Presentation Of Case: A 76-year-old male suffering from a rare case of severe oral lichen planus that was resistant to conservative measures is described. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317303PMC
November 2018

Tumescent Liposuction-Induced Koebnerization of Lichen Planus.

Dermatol Surg 2019 Jan 2. Epub 2019 Jan 2.

Baylor College of Medicine, Houston, Texas Westlake Dermatology Clinical Research Center, Westlake Dermatology & Cosmetic Surgery, Austin, Texas Division of Dermatology and Cutaneous Surgery, The University of Texas Health Science Center at San Antonio, San Antonio, Texas.

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http://dx.doi.org/10.1097/DSS.0000000000001752DOI Listing
January 2019
6 Reads