540 results match your criteria Lichen Myxedematosus


Plasma Cell Myeloma Masquerading as Scleromyxedema.

Indian Dermatol Online J 2019 Jan-Feb;10(1):50-53

Department of General Medicine, St. John's Medical College, Bengaluru, Karnataka, India.

Scleromyxedema is a rare progressive cutaneous mucinosis of unknown etiology with equal prevalence in both men and women. It is usually associated with monoclonal gammopathy in most of the cases. Various treatment modalities have been tried for scleromyxedema including steroids, intravenous immunoglobulin (IVIg), autologous hematopoietic stem cell transplantation, and melphalan, but none has proved to be fully effective. Read More

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http://dx.doi.org/10.4103/idoj.IDOJ_135_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362738PMC
February 2019

Unwelcomed face of scleromyxedema.

Int J Dermatol 2019 Feb 11. Epub 2019 Feb 11.

Mansoura Dermatology, Venerology and Leprology Hospital, Mansoura, Egypt.

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http://dx.doi.org/10.1111/ijd.14400DOI Listing
February 2019

Cutaneous paraneoplastic syndromes.

Semin Diagn Pathol 2019 Jan 31. Epub 2019 Jan 31.

PRW Laboratories, Charlottesville, VA, United State.

A variety of cutaneous abnormalities can be seen in patients with malignant diseases, some of which are infectious, with others representing direct involvement of the skin by the underlying disorder. Yet another group of lesions can be regarded as associated markers of the malignant process, and, as such, are termed "paraneoplastic." This review considers the latter collection of conditions, grouping them by the generic type of malignancy that is usually linked to the paraneoplasia. Read More

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http://dx.doi.org/10.1053/j.semdp.2019.01.001DOI Listing
January 2019
1 Read

ACUTE MYOCARDITIS WITH CARDIOGENIC SHOCK AND MULTIPLE ORGAN FAILURE, FOLLOWED BY BILATERAL PANUVEITIS MASQUERADING AS ENDOGENOUS ENDOPHTHALMITIS, DUE TO TOXOPLASMA GONDII IN AN IMMUNOCOMPETENT PATIENT.

Retin Cases Brief Rep 2019 Jan 17. Epub 2019 Jan 17.

Massachusetts Eye Research and Surgery Institution (MERSI), Waltham, Massachusetts.

Purpose: To report a case of systemic and ocular toxoplasmosis in an immunocompetent patient, who developed myocarditis with resulting cardiogenic shock and multiple organ failure, followed by bilateral panuveitis masquerading as endogenous endophthalmitis.

Methods: Single case report with images.

Results: A 59-year-old man with a history of monoclonal gammopathy of undetermined significance and associated scleromyxedema but otherwise immunocompetent was admitted to the intensive care unit for cardiogenic shock and multiple organ failure due to presumed viral myocarditis. Read More

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http://dx.doi.org/10.1097/ICB.0000000000000855DOI Listing
January 2019
4 Reads

Localized Lichen Myxedematosus With Plasma Cell Light Chain Restriction. Is It the Exception or the Rule?

Am J Dermatopathol 2018 Dec 20. Epub 2018 Dec 20.

Global Pathology Laboratory, Aurora Diagnostics, Miami Lakes, FL.

Lichen myxedematosus is a chronic cutaneous mucinosis that can present on a spectrum from localized cutaneous lesions to systemic disease of scleromyxedema. The clinical presentation of localized cutaneous lichen myxedematosus is waxy lichenoid papules, nodules, and/or plaques that have histopathologic findings of mucin deposition and a variable degree of fibroblast proliferation. There is an absence of serum paraproteins, and there are no other systemic causes of cutaneous mucinosis such as thyroid disease. Read More

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http://dx.doi.org/10.1097/DAD.0000000000001335DOI Listing
December 2018
3 Reads

Scleromyxoedema: the importance of physical examination.

BMJ Case Rep 2018 Oct 12;2018. Epub 2018 Oct 12.

Unit of Clinical Immunology, Centro Hospitalar Porto, Porto, Portugal.

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22714
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http://dx.doi.org/10.1136/bcr-2018-227144DOI Listing
October 2018
10 Reads

[Mimetics of systemic sclerosis].

Z Rheumatol 2019 Feb;78(1):14-23

Klinik für Rheumatologie und klinische Immunologie, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Deutschland.

Background: Systemic sclerosis (SSc) is characterized by heterogeneous clinical symptoms. Peripheral skin fibrosis can be a common symptom. Nevertheless, a variety of diseases with different etiologies are associated with a thickening of the skin and make the initial diagnosis of systemic sclerosis more difficult. Read More

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http://dx.doi.org/10.1007/s00393-018-0538-yDOI Listing
February 2019
12 Reads

[Scleromyxedema].

Hautarzt 2018 Nov;69(11):916-921

Universitätsklinik und Poliklinik für Dermatologie und Venerologie, Universitätsklinikum Halle (Saale), Martin-Luther-Universität Halle-Wittenberg, Halle, Deutschland.

Scleromyxedema is a rare disorder that frequently affects multiple extracutaneous organ systems and is usually associated with monoclonal gammopathy. The pathogenesis of scleromyxedema is unknown. The clinical course is chronic and progressive and can lead to marked morbidity or death. Read More

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http://dx.doi.org/10.1007/s00105-018-4257-8DOI Listing
November 2018
3 Reads

[Scleromyxedema as a systemic disease of glycosaminoglycan accumulation].

Arkh Patol 2018 ;80(3):53-58

V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia.

Scleromyxedema is a rare mucinosis with a primary skin lesion due to diffuse mucin deposition, sclerosis, and lichenoid eruptions in the absence of hypothyroidism. The paper describes scleromyxedema cases and gives recommendations for the histological diagnosis of the disease by histochemical reactions to detect acid and neutral glycosaminoglycans. Read More

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http://dx.doi.org/10.17116/patol201880353-58DOI Listing
January 2018

Monoclonal Gammopathy-Associated Scleromyxedema Presenting as Leonine Facies.

Arthritis Rheumatol 2018 Oct;70(10):1694

University of Michigan, Ann Arbor, MI.

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http://dx.doi.org/10.1002/art.40530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160324PMC
October 2018
3 Reads

Breast cancer cutaneous metastases mimicking Papilloma Cutis Lymphostatica. Biopsy to avoid pitfalls.

Int J Surg Case Rep 2018 10;46:31-33. Epub 2018 Apr 10.

Department of Plastic and Reconstructive Surgery, University of Bari, Italy.

Introduction: Secondary lymphedema is the most frequent long-term complication of axillary lymphadenectomy. It can result in complication as erysipelas, warts, Papilloma Cutis Lymphostatica (PCL), or angiosarcomas. Moreover, in women affected by breast cancer an accurate differential diagnosis among these conditions or complication related to radiation dermatitis or cutaneous metastasis is essential. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.03.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000767PMC
April 2018
8 Reads

[Is scleromyxedema a skin problem or systemic pathological process?]

Arkh Patol 2018 ;80(1):63-66

N.I. Pirogov Russian National Research Medical University, Moscow, Russia.

Scleromyxedema is regarded as a rare cutaneous mucinosis from a group of lichen myxedematosus characterized by diffuse mucin deposition, sclerosis, and lichenoid eruptions in the absence of thyroid disease. The paper discusses the pathogenesis of the disease and histological changes in tissues. It underlines the need for using histochemical tests to identify acidic and neutral glycosaminoglycans and gives a differential diagnosis of this disease. Read More

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http://dx.doi.org/10.17116/patol201880163-66DOI Listing
January 2018

Papular mucinosis, or localized lichen myxedematosis (LM) (discrete papular type).

Dermatol Online J 2017 Dec 15;23(12). Epub 2017 Dec 15.

New York University Langone Health, New York.

Lichen myxedematosus is condition characterized by localized areas of dermal deposition of mucin, presenting with firm papules localized to few areas of the body. The condition needs to be excluded from scleromyxedema, which, in addition to the firm papular eruption, has areas of induration and is usually associated with a monoclonal gammopathyand systemic symptoms. We present a 62-year-old woman with a several-year history of asymptomatic, firm papules over the face and arms with no evidence of thyroid disease or a monoclonal gammopathy,which is consistent with a diagnosis of localized lichen myxedematosus, the discrete papular variant. Read More

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December 2017
7 Reads

Paraneoplastic plaque-like cutaneous mucinosis in a patient with lung adenocarcinoma.

J Cutan Pathol 2018 04 6;45(4):305-307. Epub 2018 Feb 6.

Department of Dermatology, University of Texas McGovern Medical School, Houston, Texas.

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http://doi.wiley.com/10.1111/cup.13094
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http://dx.doi.org/10.1111/cup.13094DOI Listing
April 2018
7 Reads
1.560 Impact Factor

Scleroderma with an update about clinico-pathological correlation.

G Ital Dermatol Venereol 2018 Apr 24;153(2):208-215. Epub 2018 Jan 24.

Department of Molecular Medicine, "Sapienza" University, Rome, Italy.

Scleroderma is divided into a systemic form called systemic sclerosis and a localized form also called morphea. According to 2013 ACR/EULAR Classification Criteria for Systemic Sclerosis, developed by the American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR), skin thickening of the fingers extending proximal to the metacarpophalangeal joints is sufficient for a patient to be classified as having scleroderma. Histological examination is not included in the diagnostic criteria and is not routinely performed. Read More

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http://dx.doi.org/10.23736/S0392-0488.18.05922-9DOI Listing
April 2018
7 Reads

High-dose intravenous immunoglobulins for the treatment of dermatological autoimmune diseases.

J Dtsch Dermatol Ges 2017 Dec;15(12):1211-1226

Department of Dermatology, University of Heidelberg, Heidelberg, Germany.

Based on their immunomodulatory properties, high-dose intravenous immunoglobulins (IVIGs) are successfully used in the treatment of various dermatological autoimmune diseases, in particular pemphigus vulgaris and dermatomyositis. In autoimmune bullous diseases, IVIGs can be used in an adjuvant setting (second- or third-line therapy) once combined immunosuppressive regimens have failed. In dermatomyositis, IVIGs may already be employed as an adjuvant second-line therapy after failure of corticosteroid monotherapy. Read More

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http://dx.doi.org/10.1111/ddg.13389DOI Listing
December 2017
17 Reads

Ineffectiveness of infliximab CT-P13 for the treatment of scleromyxedema: A case report.

Dermatol Ther 2018 Mar 7;31(2):e12583. Epub 2017 Dec 7.

Dermatology Clinic, Azienda Ospedaliero-Universitaria Policlinico di Modena, Italy.

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http://dx.doi.org/10.1111/dth.12583DOI Listing
March 2018
7 Reads

Interstitial Granulomatous Variant of Scleromyxedema-A Diagnostic Pitfall.

Am J Dermatopathol 2018 Apr;40(4):279-282

National Skin Centre, Singapore.

Scleromyxedema is a rare disorder where patients may develop systemic manifestations such as monoclonal gammopathy, inflammatory polyarthritis, and esophageal and neurological dysfunction. Histologically, there may be atypical variants of scleromyxedema showing features resembling interstitial granuloma annulare. We report an unusual case of scleromyxedema with interstitial granulomatous pattern and highlight potential diagnostic pitfalls when encountered with such a variant. Read More

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http://dx.doi.org/10.1097/DAD.0000000000000988DOI Listing
April 2018
7 Reads

Pathophysiological Mechanisms in Sclerosing Skin Diseases.

Front Med (Lausanne) 2017 18;4:120. Epub 2017 Aug 18.

Department of Dermatology, University of Cologne, Cologne, Germany.

Sclerosing skin diseases represent a large number of distinct disease entities, which include systemic sclerosis, localized scleroderma, and scleredema adultorum. These pathologies have a common clinical appearance and share histological features. However, the specific interplay between cytokines and growth factors, which activate different mesenchymal cell populations and production of different extracellular matrix components, determines the biomechanical properties of the skin and the clinical features of each disease. Read More

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http://dx.doi.org/10.3389/fmed.2017.00120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563304PMC
August 2017
7 Reads

Paraneoplastic atypical scleromyxedema with advanced gastric cancer.

JAAD Case Rep 2017 Sep 12;3(5):376-378. Epub 2017 Aug 12.

Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1016/j.jdcr.2017.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555091PMC
September 2017
3 Reads

European dermatology forum S1-guideline on the diagnosis and treatment of sclerosing diseases of the skin, Part 2: Scleromyxedema, scleredema and nephrogenic systemic fibrosis.

J Eur Acad Dermatol Venereol 2017 Oct 8;31(10):1581-1594. Epub 2017 Aug 8.

Department of Dermatology and Venereology, University Hospital of Cologne, Cologne, Germany.

The term 'sclerosing diseases of the skin' comprises specific dermatological entities which have fibrotic changes of the skin in common. These diseases mostly manifest in different clinical subtypes according to cutaneous and extracutaneous involvement and can sometimes be difficult to distinguish from each other. The present guideline focuses on characteristic clinical and histopathological features, diagnostic scores and the serum autoantibodies most useful for differential diagnosis. Read More

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http://dx.doi.org/10.1111/jdv.14466DOI Listing
October 2017
11 Reads

Cutaneous Manifestations of Scleroderma and Scleroderma-Like Disorders: a Comprehensive Review.

Clin Rev Allergy Immunol 2017 Dec;53(3):306-336

Section of Dermatology, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.

Scleroderma refers to an autoimmune connective tissue fibrosing disease, including three different subsets: localized scleroderma, limited cutaneous systemic sclerosis, and diffuse cutaneous systemic sclerosis with divergent patterns of organ involvement, autoantibody profiles, management, and prognostic implications. Although systemic sclerosis is considered the disease prototype that causes cutaneous sclerosis, there are many other conditions that can mimic and be confused with SSc. They can be classified into immune-mediated/inflammatory, immune-mediated/inflammatory with abnormal deposit (mucinoses), genetic, drug-induced and toxic, metabolic, panniculitis/vascular, and (para)neoplastic disorders according to clinico-pathological and pathogenetic correlations. Read More

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http://dx.doi.org/10.1007/s12016-017-8625-4DOI Listing
December 2017
30 Reads

Review of Primary Cutaneous Mucinoses in Nonlupus Connective Tissue Diseases.

J Cutan Med Surg 2018 Jan/Feb;22(1):65-70. Epub 2017 Jul 3.

1 Division of Dermatology, Cumming School of Medicine, Calgary, AB, Canada.

Lichen myxedematosus is an idiopathic, cutaneous mucinosis with 2 clinicopathologic subsets. There is the generalised papular and sclerodermoid form, more properly termed scleromyxedema, and the localised papular form. We report the first case, to our knowledge, of lichen myxedematosus in association with rheumatoid arthritis as well as a case in association with dermatomyositis. Read More

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http://dx.doi.org/10.1177/1203475417719053DOI Listing
August 2018
2 Reads

[Granulomatous reaction pattern of the skin : Interstitial granulomatous dermatitis - lymphoma - vasculitis].

Hautarzt 2017 Jul;68(7):553-559

Konsultations- und Referenzzentrum für Vaskulitis-Diagnostik, MVZ am Marienkrankenhaus gGmbH, Hamburg, Deutschland.

A particular diagnostic situation in the classification of a granulomatous dermatitis results when no circumscribed granulomas but instead a diffuse interstitial histiocytic inflammatory infiltrate, a granulomatous vasculitis or a neoplastic lymphocytic infiltrate is found. Interstitial granulomatous dermatitis was originally described in patients with arthritis. Later, it was recognized that there are also associations with other usually immunological diseases. Read More

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http://dx.doi.org/10.1007/s00105-017-4004-6DOI Listing
July 2017
2 Reads

Scleroderma-like Disorders.

Authors:
Amit Sharma

Curr Rheumatol Rev 2018 Apr;14(1):22-27

Fortis Escorts Hospital, Jaipur, Rajasthan, India.

Background: Scleroderma is a term used to describe diseases that involve hardening and tightening of the skin and the underlying subcutaneous connective tissue. It could be localized to skin and subcutaneous tissue, or may involve the internal organs too in systemic sclerosis.

Objective: There are disorders that can cause hardening and tightening of skin and mimic scleroderma but are rarely associated with Raynaud phenomenon, sclerodactyly, and autoantibodies in the serum, features specific to scleroderma/systemic sclerosis. Read More

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http://dx.doi.org/10.2174/1573397113666170612091419DOI Listing
April 2018
22 Reads

Atypical Lichen Myxedematosus: A Case with Remarkable Response to Low Dose Melphalan.

Indian Dermatol Online J 2017 May-Jun;8(3):198-200

Department of Dermatology and Venereology, Government Medical College, Alappuzha, Kerala, India.

A 41-year-old man was referred to our outpatient department with a diagnosis of urticaria with angioedema of 3 months duration. On examination, he had generalized coalescent waxy papules and diffuse periorbital swelling. Systemic examination was unremarkable except for limited finger flexion. Read More

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http://www.idoj.in/text.asp?2017/8/3/198/206116
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http://dx.doi.org/10.4103/idoj.IDOJ_159_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447341PMC
June 2017
8 Reads

Scleroderma Mimickers.

Curr Treatm Opt Rheumatol 2016 Mar 5;2(1):69-84. Epub 2016 Feb 5.

Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Cutaneous fibrosing disorders encompass a diverse array of diseases united by the presence of varying degrees of dermal sclerosis. The quality and distribution of skin involvement, presence or absence of systemic complications and unique associated laboratory abnormalities often help to distinguish between these diseases. It is imperative that an effort is made to accurately differentiate between scleroderma and its mimics, in order to guide long-term management and facilitate implementation of the appropriate treatment modality where indicated. Read More

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http://dx.doi.org/10.1007/s40674-016-0038-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412724PMC
March 2016
16 Reads

Lichen myxedematosus: how to reach the accurate diagnosis.

Int J Dermatol 2017 09 28;56(9):e181-e182. Epub 2017 Apr 28.

Dermatology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

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http://dx.doi.org/10.1111/ijd.13619DOI Listing
September 2017
22 Reads

A Case of Autoimmune Polyglandular Syndrome .ype 2 Associated with Atypical Form of Scleromyxedema.

Ethiop J Health Sci 2016 Sep;26(5):503-507

Department of Clinical Immunology, Allergology and Endocrinology, Donetsk National Medical University, Ukraine.

Background: Autoimmune polyglandular syndrome type 2 represents an uncommon endocrine disorder composed by Addison's disease with autoimmune thyroid disease (Schmidt's syndrome) and/or type 1 diabetes mellitus. Scleromyxedema is a rare progressive cutaneous mucinosis usually associated with systemic involvement and paraproteinemia. To the best of our knowledge, there is no case report of Schmidt's syndrome associated with scleromyxedema. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389067PMC
September 2016
6 Reads

Scleromyxoedema in a dog.

Vet Dermatol 2017 Oct 24;28(5):503-e119. Epub 2017 Apr 24.

Center for Comparative Medicine and Translational Research, North Carolina State University College of Veterinary Medicine, 1060 William Moore Drive, Raleigh, NC, 27607, USA.

Background: In humans, scleromyxoedema is a chronic progressive skin condition traditionally characterized by deposits of mucin, increased number of fibroblasts and fibrosis in the skin, and by systemic disease. Thyroid disease is typically absent. A monoclonal gammopathy is usually present, as are other comorbidities. Read More

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http://doi.wiley.com/10.1111/vde.12447
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http://dx.doi.org/10.1111/vde.12447DOI Listing
October 2017
16 Reads

Uncommon Presentation of Scleromyxoedema with a Distribution Pattern Mimicking a Photodermatosis.

Acta Derm Venereol 2017 Aug;97(8):979-980

Department of Dermatology, University Erlangen, Ulmenweg 18, DE-91052 Erlangen, Germany.

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https://www.medicaljournals.se/acta/content/abstract/10.2340
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http://dx.doi.org/10.2340/00015555-2684DOI Listing
August 2017
5 Reads

High-dose intravenous immunoglobulin therapy for scleromyxoedema: a prospective open-label clinical trial using an objective score of clinical evaluation system.

J Eur Acad Dermatol Venereol 2017 Jul 12;31(7):1157-1160. Epub 2017 Apr 12.

Unit of Dermatology, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.

Background: Scleromyxoedema is a primary fibro-mucinosis whose therapy is still challenging.

Objective: To evaluate the safety and efficacy of high-dose intravenous immunoglobulin (IVIg) for the management of scleromyxoedema prospectively using an objective score.

Methods: In a prospective open-label study, IVIg was administered to eight patients with scleromyxoedema in a dose of 2 g/kg per month. Read More

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http://dx.doi.org/10.1111/jdv.14244DOI Listing

Cutaneous mucinosis in a patient taking ustekinumab for palmoplantar psoriasis.

Dermatol Online J 2017 Mar 15;23(3). Epub 2017 Mar 15.

Department of Dermatology, Tufts Medical Center, Boston, MA Tufts University School of Medicine, Boston, MA.

Discrete papular lichen myxedematosus (DPLM), asubset of localized lichen myxedematosus, is a rarecutaneous mucinosis of unknown etiology. We reporta case of a 57-year-old woman with palmoplantarpsoriasis who developed DPLM 8 weeks after addingustekinumab to a long-term course of methotrexate.The patient had previously failed 2 prior tumor necrosisfactor (TNF) inhibitors, adalimumab and etanercept. Read More

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March 2017
10 Reads

Acral papular mucinosis: a new case of this rare entity.

An Bras Dermatol 2016 Sep-Oct;91(5 suppl 1):111-113

Complejo Universitario Hospitalario de Albacete - Castilla la Mancha, Spain.

Acral persistent papular mucinosis (APPM) is a rare subtype of localized lichen myxedematosus. It consists of small papules localized exclusively on the back of the hands, wrists and extensor aspects of distal forearms with no other clinical or laboratory manifestations. The lesions tend to persist and may increase slowly in number. Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
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http://dx.doi.org/10.1590/abd1806-4841.20164804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325012PMC
July 2017
3 Reads

Scleromyxedema: clinical diagnosis and autopsy findings.

An Bras Dermatol 2016 Sep-Oct;91(5 suppl 1):48-50

Private clinic - São Luís (MA) - Brazil.

Scleromyxedema is a rare chronic cutaneous mucinosis of unknown etiology. It is characterized by papular eruption and scleroderma with microscopic evidence of mucin deposition, fibroblast proliferation, and fibrosis. Most patients with scleromyxedema have monoclonal gammopathy and systemic manifestations resulting in significant morbidity and mortality. Read More

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http://dx.doi.org/10.1590/abd1806-4841.20164527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324991PMC
July 2017
3 Reads

A case of scleromyxedema responding to lenalidomide and dexamethasone.

Indian Dermatol Online J 2017 Jan-Feb;8(1):50-53

Department of Dermatology, Consultant Oncologist, Bhakti Vedanta Hospital, Mumbai, Maharashtra, India.

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http://www.idoj.in/text.asp?2017/8/1/50/198779
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http://dx.doi.org/10.4103/2229-5178.198779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297274PMC
February 2017
2 Reads

Lichen myxedematosus: eine Fallserie mit Schwerpunkt auf klinischen Merkmalen, Krankheitsassoziationen und Behandlung.

J Dtsch Dermatol Ges 2017 Feb;15(2):214-217

Department of Dermatology and Venereology, Istanbul Medical Faculty, Istanbul University.

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http://doi.wiley.com/10.1111/ddg.12970_g
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http://dx.doi.org/10.1111/ddg.12970_gDOI Listing
February 2017
4 Reads

Papulonodular mucinosis, Guillain-Barré syndrome and nephrotic syndrome in a patient with systemic lupus erythematosus: a case report.

BMC Nephrol 2017 Feb 1;18(1):43. Epub 2017 Feb 1.

Renal Division, Shanxi Medical University Second Hospital, Shanxi Kidney Disease Institute, No.382, Wuyi Road, Xinghualing Distirct, Taiyuan, Shanxi Province, China.

Background: Awareness of the spectrum of clinical manifestations of systemic lupus erythematosus (SLE), especially uncommon changes, is essential for diagnosis and effective management of patients.

Case Presentation: A 26-year-old Chinese man with SLE initially manifested cutaneous papulonodular mucinosis and developed acute Guillain-Barré syndrome and class V lupus nephritis 2 years later. His cutaneous nodules had not been idententified for 2 years and were resected by surgical procedures twice until SLE was diagnosed. Read More

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http://dx.doi.org/10.1186/s12882-017-0458-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286654PMC
February 2017
6 Reads

Lichen myxedematosus: toward established classification and diagnostic criteria: Response to the letter 'Lichen myxedematosus: suggestions on the newly proposed diagnostic criteria'.

Int J Dermatol 2017 04 29;56(4):e78. Epub 2017 Jan 29.

Dermatology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

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http://dx.doi.org/10.1111/ijd.13522DOI Listing
April 2017
6 Reads

Lichen myxedematosus: suggestions on the newly proposed diagnostic criteria.

Int J Dermatol 2017 04 21;56(4):e77-e78. Epub 2017 Jan 21.

Mansoura Dermatology, Venerology and Leprology Hospital, Mansoura, Egypt.

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http://doi.wiley.com/10.1111/ijd.13519
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http://dx.doi.org/10.1111/ijd.13519DOI Listing
April 2017
6 Reads

Case for diagnosis. Lichen myxedematosus.

An Bras Dermatol 2016 Nov-Dec;91(6):842-843

Faculdade Evangélica do Paraná (Fepar) - Curitiba (PR), Brazil.

Scleromyxedema or lichen myxedematosus is a rare papular mucinosis of chronic and progressive course and unknown etiology. It is commonly associated with monoclonal gammopathy and may show extracutaneous manifestations, affecting the heart, lung, kidney, and nerves. The diagnosis is based on four criteria: generalized papular and sclerodermoid lesions; mucin deposition, fibroblast proliferation, and fibrosis in the histopathology; monoclonal gammopathy; and no thyroid disorders. Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
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http://dx.doi.org/10.1590/abd1806-4841.20165725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193206PMC
May 2017
23 Reads

Flesh-colored papular eruption.

Cutis 2016 Dec;98(6):361-363

Department of Dermatology, Saint Louis University, Missouri, USA.

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December 2016
4 Reads

Acral persistent papular mucinosis (APPM): Dermoscopy of an uncommon disease.

J Am Acad Dermatol 2017 Feb;76(2S1):S10-S11

Department of Dermatology, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.

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http://dx.doi.org/10.1016/j.jaad.2016.03.046DOI Listing
February 2017
3 Reads

Lichen myxedematosus: a case series focusing on clinical features, disease associations, and management.

J Dtsch Dermatol Ges 2017 Feb 13;15(2):215-218. Epub 2017 Jan 13.

Department of Dermatology and Venereology, Istanbul Medical Faculty, Istanbul University.

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http://dx.doi.org/10.1111/ddg.12970DOI Listing
February 2017
2 Reads

Scleromyxedema without Paraproteinemia: Treatment with Thalidomide and Prednisolone.

Case Rep Dermatol 2016 Sep-Dec;8(3):327-332. Epub 2016 Nov 21.

Department of Dermatology, Tabriz University of Medical Science, Tabriz, Iran.

Scleromyxedema is a rare and distinctive variant of cutaneous mucinoses of unknown etiology. It is presenting with generalized papular eruption and sclerodermoid induration. Numerous treatment modalities have been reported to produce partial or permanent responses. Read More

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https://www.karger.com/Article/FullText/452319
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http://dx.doi.org/10.1159/000452319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156886PMC
November 2016
4 Reads

Scleromyxoedema.

Lancet 2017 04 26;389(10078):1549. Epub 2016 Nov 26.

Department of Dermatology, Maastricht University Medical Center, Netherlands.

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http://dx.doi.org/10.1016/S0140-6736(16)31401-5DOI Listing
April 2017
1 Read

[Therapeutic administration of immunoglobulins].

Authors:
T Witte

Z Rheumatol 2016 Dec;75(10):956-963

Klinik für Immunologie und Rheumatologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland.

Background: Intravenously administered immunoglobulins have multiple modes of action that are anti-inflammatory. They can therefore be beneficial in a number of autoimmune disorders.

Objective: The aim of this article is to analyze and summarize studies on the administration of intravenous immunoglobulins in rheumatological diseases. Read More

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http://link.springer.com/10.1007/s00393-016-0217-9
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http://dx.doi.org/10.1007/s00393-016-0217-9DOI Listing
December 2016
3 Reads