Biomolecules 2022 Apr 19;12(5). Epub 2022 Apr 19.
Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, The WHO Collaborating Centre for Oral Cancer, London SE1 9RT, UK.
Our aim was to evaluate the expression of biomarkers, CD44v6, CD147, EGFR, p53, p63, p73, p16, and podoplanin in oral leukoplakias (OL) and to assess their potential for prediction of malignant transformation (MT). We analyzed the expression of CD44v6, CD147, EGFR, p53, p63, p73, p16, and podoplanin by immunohistochemistry in 52 OL, comprised of 41 low-grade (LG) dysplasia and 11 high-grade (HG) cases. Twelve healthy normal tissues (NT) were also included. Read More