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    2928 results match your criteria Leukocytoclastic Vasculitis

    1 OF 59

    Clinical study on single-organ cutaneous small vessels vasculitis (SoCSVV).
    Medicine (Baltimore) 2017 Mar;96(12):e6376
    aDepartment of Dermatology b2nd Department of Medicine, Jagiellonian University Medical College, Cracow, Poland.
    Leukocytoclastic vasculitis (LCV) is a heterogenous group of disorders that may manifest as a mild disease isolated to the skin or be a part of life-threatening systemic vasculitis. According to the 2012 Chapel Hill Consensus Conference nomenclature, patients presenting symptoms of LCV confined only to the skin should be defined as suffering from a single-organ cutaneous small vessel vasculitis (SoCSVV). SoCSVV is a benign disease with a good clinical outcome but with a significant risk of relapse and skin ulcer formation. Read More

    Scabietic vasculitis: Report of 2 cases.
    Ann Dermatol Venereol 2017 Mar 18. Epub 2017 Mar 18.
    Service de dermatologie, hôpital Nord, chemin des Bourrely, 13015 Marseille, France.
    Background: The infectious causes of cutaneous vasculitis are well known and include streptococcal infections among others. Cases resulting from parasitic infection are less frequent. Scabies, which is currently on the increase, has only been reported in a few isolated cases. Read More

    Dapsone-induced agranulocytosis - possible involvement of low activity N-acetyltransferase 2.
    Fundam Clin Pharmacol 2017 Mar 21. Epub 2017 Mar 21.
    University of Zagreb School of Medicine, Zagreb, Croatia.
    Dapsone-induced agranulocytosis is a rare but potentially fatal adverse drug reaction (ADR). A 45-year old male Caucasian patient developed agranulocytosis caused by dapsone (diamino-diphenyl sulfone) which he was prescribed for leukocytoclastic vasculitis. Patient's treatment consisted of termination of dapsone, antibiotic therapy, and granulocyte colony stimulating factor leading to prompt improvement of symptoms and normalization of laboratory blood values. Read More

    Interferon-gamma-induced local leukocytoclastic vasculitis at the subcutaneous injection site.
    An Bras Dermatol 2016 Sep-Oct;91(5 suppl 1):76-78
    The Eastern Hospital of The First Affiliated Hospital, Sun Yat-sen University - Guangzhou, China.
    Cutaneous reactions associated with interferons (IFNs) treatment are either localized or generalized. The most common presentation of localized reactions at IFNs injection site is usually an erythematous patch or plaque. Local leukocytoclastic vasculitis presenting with cutaneous necrosis is extremely rare. Read More

    Immunoglobulin G4-related disease and its skin manifestations.
    J Dermatol 2017 Mar;44(3):288-296
    Department of Dermatology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.
    Immunoglobulin G4-related disease (IgG4-RD) is a systemic inflammatory condition characterized by tissue infiltration with IgG4(+) plasma cells and an elevated serum IgG4 level. It usually occurs in middle-aged or older patients, with male predominance, and can involve multiple organs synchronously or metachronously. Patients with IgG4-RD generally respond to steroid therapy. Read More

    Acute Hemorrhagic Edema of Infancy after Coronavirus Infection with Recurrent Rash.
    Case Rep Pediatr 2017 24;2017:5637503. Epub 2017 Jan 24.
    Department of Pediatrics, University of North Carolina, Chapel Hill, NC, USA.
    Purpura, particularly when accompanied by fever, is a worrisome finding in children. Acute hemorrhagic edema of infancy (AHEI) is a benign type of small-vessel leukocytoclastic vasculitis that presents with progressive purpura and has an excellent prognosis. Patients with AHEI present with large, target-like purpuric plaques affecting the face, ear lobes, and extremities. Read More

    [Acute generalized exanthematous pustulosis induced by phloroglucinol].
    Ann Dermatol Venereol 2017 Feb 24. Epub 2017 Feb 24.
    Service de dermatologie, hôpital Bichat, université Denis-Diderot, Sorbonne Paris Cité, AP-HP, 46, rue Henri-Huchard, 75877 Paris cedex 18, France.
    Background: Acute generalized exanthematous pustulosis (AGEP) is a severe drug eruption. We report herein the first case of AGEP induced by phloroglucinol (Spasfon(®)).

    Patients And Methods: A 27-year-old pregnant woman developed a febrile exanthematous pustulosis eruption three days after treatment with intravenous phloroglucinol and paracetamol for nephritic colic. Read More

    [Acute pancreatitis as the presenting feature of an IgA vasculitis: An unusual presentation].
    Rev Med Interne 2017 Feb 16. Epub 2017 Feb 16.
    Service de médecine interne et immunologie clinique, hôpital universitaire de Bicêtre, AP-HP, 78, rue du Général-Leclerc, 94275 Le Kremlin-Bicêtre, France; Faculté de médecine, université Paris-Sud, 94275 Le Kremlin-Bicêtre, France; IDMIT, CEA, DSV/iMETI, division d'immunovirologie, 92260 Fontenay-aux-Roses, France; Inserm, U1184, centre d'immunologie des maladies virales et autoimmunes, 94275 Le Kremlin-Bicêtre, France.
    Introduction: IgA vasculitis is a systemic small vessel leukocytoclastic vasculitis characterized by skin purpura, arthritis, abdominal pain and nephritis. Most of the abdominal complications are due to edema and hemorrhage in the small bowel wall, but rarely to acute secondary pancreatitis.

    Case Report: Here, we report a 53-year-old woman who presented with acute pancreatitis and, secondarily, developed skin purpura and arthritis at the seventh day of the clinical onset. Read More

    Histopathology of bilateral lower extremity inflammatory lymphedema in military basic trainees: A leukocytoclastic vasculitis of the deep vascular plexus.
    J Cutan Pathol 2017 Feb 14. Epub 2017 Feb 14.
    Colorado Springs Health Partners PC, Department of Dermatology and Dermatopathology, Colorado Springs, Colorado.
    Bilateral lower extremity inflammatory lymphedema (BLEIL) is a recently described condition that presents with exquisite tenderness, erythema and edema of the lower leg, ankle and dorsal foot resembling an acute cellulitis. It was first reported in healthy, young adult military basic trainees with a normal body mass index during the first 72 hours of arrival to basic training. It occurs while standing at attention for many hours, and shows rapid resolution with elevation and rest. Read More

    Leukocytoclastic vasculitis associated with endocarditis in a patient with transposition of the great arteries and mechanical valve replacement.
    Cardiovasc Pathol 2017 Mar - Apr;27:68-70. Epub 2017 Jan 24.
    Department of Cardiology and Angiology, Hannover Medical School, Hannover, Germany.
    Immunological vascular phenomena can be the initial manifestation of bacterial infection and endocarditis. Here, we report a rare case of leukocytoclastic vasculitis without immune complexes or cryoglobulinemia in a patient with infective endocarditis, congenital heart disease, and a prior mechanical valve replacement. The patient completely recovered following antibiotic therapy, and skin lesions disappeared without immune suppression, which suggested infection-mediated vasculitis. Read More

    Multicentric Castleman's disease associated with IgA vasculitis (Henoch-Schönlein purpura) responding well to tocilizumab: a case report.
    Clin Rheumatol 2017 Mar 6;36(3):729-733. Epub 2017 Feb 6.
    Nephrology Center, Toranomon Hospital, 2-2-2, Toranomon, Minato, Tokyo, 105-8470, Japan.
    A 41-year-old man was referred to our hospital for the evaluation of hypergammaglobulinemia (IgG 2898 mg/dL and IgA 587 mg/dL), inflammation (CRP 6.7 mg/dL and serum interleukin-6 (IL-6) 15.1 ng/L), and anemia (Hb 10. Read More

    ANCA Associated Vasculitis Secondary to Levamisole-Adultered Cocaine with Associated Membranous Nephropathy: A Case Series.
    Am J Nephrol 2017 28;45(3):209-216. Epub 2017 Jan 28.
    Department of Medicine, University of Manitoba, Winnipeg, MB, Canada.
    Background: Cocaine is a risk factor for acute kidney injury and chronic kidney disease with progression to end-stage renal disease. Levamisole is an adulterant that is added to cocaine to enhance its euphoric effects. Levamisole-adulterated cocaine (LAC) is associated with the distinct clinical syndromes of agranulocytosis, leukocytoclastic vasculitis, cocaine-induced midline destructive lesions (CIMDL), and ANCA-associated vasculitis (AAV) with pauci-immune necrotizing glomerulonephritis. Read More

    Annular lesions of cutaneous sarcoidosis with granulomatous vasculitis.
    J Cutan Pathol 2017 Jan 24. Epub 2017 Jan 24.
    Department of Dermatology, Kansai Medical University, Osaka, Japan.
    Sarcoidosis is known to be involved in diseases with vasculitis as sarcoid vasculitis. However, vasculitis in cutaneous sarcoidal lesions is extremely rare. Here we describe a case of sarcoidosis with multiple annular skin lesions with granulomatous vasculitis. Read More

    Leukocytoclastic Vasculitis Secondary to Pyridostigmine (Mestinon): Report of a Possible First Case.
    Perm J 2017 18;21. Epub 2016 Nov 18.
    Consultant in Medicine at The Dunedin Hospital; an Honorary Clinical Senior Lecturer at the University of Otago School of Medicine in Dunedin, New Zealand; Clinical Assistant Professor of Medicine at Stanford University School of Medicine; and a Hospitalist at the Santa Clara Medical Center in CA.
    Introduction: Pyridostigmine is an acetylcholinesterase inhibitor commonly used in the treatment of myasthenia gravis. We describe a patient who developed a rash after recently being started on pyridostigmine and give a general review of leukocytoclastic vasculitis.

    Case Presentation: A 91-year-old man was diagnosed with ocular myasthenia gravis. Read More

    Leukocytoclastic Vasculitis with Systemic Involvement Associated with Ciprofloxacin Therapy: Case Report and Review of the Literature.
    Cureus 2016 Nov 28;8(11):e900. Epub 2016 Nov 28.
    Department of Internal Medicine, Hospital Centre of Algarve.
    A 71-year-old woman presented with constitutional signs and lower extremity palpable purpura after being prescribed a four-day course of 500 mg of ciprofloxacin two times daily for a gastrointestinal infection. She was admitted for inpatient treatment. During the third hospital day, she presented with an episode of abundant hematemesis while her skin lesions remained unchanged. Read More

    Dabigatran-related leukocytoclastic vasculitis.
    BMJ Case Rep 2017 Jan 4;2017. Epub 2017 Jan 4.
    Department of Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
    Dabigatran is a non-vitamin K antagonist oral anticoagulant that has been approved for atrial fibrillation and prevention of venous thromboembolism. Its use has been increasing in the USA since serum drug levels do not need monitoring. To date, no significant skin side effects have been reported other than 4 cases of non-specific skin lesion and 2 cases of leukocytoclastic vasculitis (LCV), which is a small vessel inflammatory disease that presents as palpable purpura in lower extremities. Read More

    Acrally distributed dermatoses: Vascular dermatoses (purpura and vasculitis).
    Clin Dermatol 2017 Jan - Feb;35(1):68-80. Epub 2016 Sep 10.
    Department of Dermatology and Venereology, Tokuda Hospital Sofia, Sofia, Bulgaria.
    Purpuric lesions appear in acral distribution in a variety of conditions and often provide clues to the clinical diagnosis. Purpuric means "hemorrhagic"-that is, the lesions do not blanch from pressure. This review focuses on dermatoses that produce hemorrhagic lesions in acral distribution from the large groups of the vasculitic diseases and their mimics. Read More

    Chronic Localized Fibrosing Leukocytoclastic Vasculitis Associated With Lymphedema, Intralymphatic and Intravascular Lymphocytosis, and Chronic Myelogenous Leukemia: A Case Report of Unilateral Erythema Elevatum Diutinum.
    Am J Dermatopathol 2016 Dec 7. Epub 2016 Dec 7.
    *Department of Pathology, Albany Medical College, Albany, NY; and †Departamento de Dermatología, Area de Dermatopatología, Hospital Luis Vernaza, Guayaquil, Ecuador.
    One of the pathogenic causes of cutaneous inflammatory pseudotumors is chronic localized fibrosing leukocytoclastic vasculitis (CLFLCV), a vasculitic reaction pattern seen in granuloma faciale (GF), a localized vasculitis, and erythema elevatum diutinum (EED), a generalized vasculitis. Patients with myelodysplastic syndromes (MDSs) are at risk for a diverse spectrum of cutaneous neutrophilic dermatoses such as EED. Herein, we report a 74-year-old man who presented with a large ulcerative, fungating tumor affecting the right flexor ankle caused by CLFLCV. Read More

    Cutaneous Manifestations of Multiple Myeloma.
    Indian J Dermatol 2016 Nov-Dec;61(6):668-671
    Department of Skin and VD, SCB Medical College, Cuttack, Odisha, India.
    Multiple myeloma (MM) is a proliferative disorder of plasma cells which produce abnormal immunoglobulin proteins. Skin involvement is rarely found in this disorder. They are either specific or nonspecific lesions. Read More

    Propylthiouracil-Associated Leukocytoclastic Necrotizing Cutaneous Vasculitis: A Case Report and Review of the Literature.
    J Burn Care Res 2016 Nov 11. Epub 2016 Nov 11.
    From the *Department of Surgical Sciences, Division of General Surgery, Vanderbilt University Medical Center, Nashville, Tennessee; †Department of Anesthesiology, Division of Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee; ‡Department of Surgery, Division of Burn and Wound Surgery, University of Missouri, Columbia; and §Department of Surgical Sciences, Division of Trauma and Surgical Critical Care, Vanderbilt University Medical Center, Nashville, Tennessee.
    The purpose of this case report and review of the literature is to provide an exploration of the clinical symptoms, diagnosis, prevention, and management of propylthiouracil (PTU)-associated vasculitis in the intensive care setting. A PubMed search of the available literature was conducted using the MeSH search terms "propylthiouracil" and "vasculitis." The literature search returned 121 articles. Read More

    Pulmonary Leukocytoclastic Vasculitis as an Initial Presentation of Myelodysplastic Syndrome.
    Tuberc Respir Dis (Seoul) 2016 Oct 5;79(4):302-306. Epub 2016 Oct 5.
    Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
    Systemic vasculitis involving the lung is a rare manifestation of myelodysplastic syndrome (MDS), and secondary vasculitis is considered to have poor prognosis. A 44-year-old man presented with fever and dyspnea of 1 month duration. A chest radiograph revealed bilateral multiple wedge shaped consolidations. Read More

    Leukocytoclastic vasculitis associated with hairy cell leukemia at diagnosis: a case report and review of the literature.
    Tumori 2016 Nov 11;102(Suppl. 2). Epub 2016 Nov 11.
    Institute of Hematology L. and A. Seràgnoli, University of Bologna, Bologna - Italy.
    Background: Autoimmune manifestations may occur in patients with hairy cell leukemia (HCL), and some rare cases of polyarteritis nodosa and leukocytoclastic vasculitis have been reported. However, data regarding the treatment of these cutaneous manifestations are lacking, given the rarity of the concomitance of HCL and vasculitic syndromes.

    Case Presentation: We present a 37-year-old man with paraneoplastic leukocytoclastic vasculitis complicating newly diagnosed HCL. Read More

    Approach to cutaneous vasculitides with special emphasis on small vessel vasculitis: histopathology and direct immunofluorescence.
    Curr Opin Rheumatol 2017 Jan;29(1):39-44
    Department of Pathology, Acıbadem University, Istanbul, Turkey.
    Purpose Of Review: The present review will focus on recent publications in cutaneous vasculitides.

    Recent Findings: Some histopathological and clinical features, such as papillary dermal edema, perivascular C3 deposition, clinically evident edema, and lesions above the waist, may point out renal or gastrointestinal involvement in Henoch-Schönlein purpura (HSP). HSP associated with familial Mediterranean fever differs from typical isolated HSP by showing no deposits of IgA, much younger age, and location of the lesions on the face or the trunk. Read More

    Revisiting the systemic vasculitis in eosinophilic granulomatosis with polyangiitis (Churg-Strauss): A study of 157 patients by the Groupe d'Etudes et de Recherche sur les Maladies Orphelines Pulmonaires and the European Respiratory Society Taskforce on eosinophilic granulomatosis with polyangiitis (Churg-Strauss).
    Autoimmun Rev 2017 Jan 23;16(1):1-9. Epub 2016 Sep 23.
    Hospices civils de Lyon, Hôpital Louis Pradel, Service de pneumologie - centre national de référence des maladies pulmonaire rares, Université de Lyon, Université Claude Bernard Lyon I, UCBL-INRA-ENVL-EPHE, UMR754, IFR128, Lyon, France.
    Objective: To guide nosology and classification of patients with eosinophilic granulomatosis with polyangiitis (EGPA) based on phenotype and presence or absence of ANCA.

    Methods: Organ manifestations and ANCA status were retrospectively analyzed based on the presence or not of predefined definite vasculitis features or surrogates of vasculitis in patients asthma, eosinophilia, and at least one systemic organ manifestation attributable to systemic disease.

    Results: The study population included 157 patients (mean age 49. Read More

    A Case of Streptobacillus moniliformis Infection with Cutaneous Leukocytoclastic Vasculitis.
    Acta Med Okayama 2016 Oct;70(5):377-381
    Department of Dermatology, Okayama City Hospital, Okayama 700-8557,
    A 71-year-old man presented with a high fever, polyarthralgia, petechiae and palpable purpura accompanied by livedoid change on his legs and feet. Histopathological findings of the purpura revealed perivascular infiltration of neutrophils, mononuclear cells, and nuclear debris, and extravasation of red cells mainly in the upper dermis: all signs consistent with leukocytoclastic vasculitis. Small vessel thrombi, which are characteristic features of septic vasculopathy, were also observed. Read More

    Cutaneous manifestations in inflammatory bowel disease: a single institutional study of non-neoplastic biopsies over 13 years.
    J Cutan Pathol 2016 Nov 26;43(11):946-955. Epub 2016 Aug 26.
    Department of Pathology, Cleveland Clinic Foundation, Cleveland, OH, USA.
    Background: Skin is commonly affected by extraintestinal manifestations of inflammatory bowel disease (IBD), but a controlled, systematic histopathologic analysis of cutaneous lesions is lacking.

    Methods: A total of 4147 classified IBD [Crohn disease (CD) or ulcerative colitis (UC); 2000-2013] resections were cross referenced with skin biopsies. Associated non-neoplastic skin biopsies were categorized by basic reaction pattern and neutrophilic vs. Read More

    Successful Corticosteroid Treatment for Purpura Fulminans Associated with Quinolone.
    Intern Med 2016;55(20):3047-3051. Epub 2016 Oct 15.
    Division of Hematology and Stem Cell Transplantation, Shizuoka Cancer Center, Japan.
    Purpura fulminans (PF) is a life-threatening syndrome comprising progressive hemorrhagic necrosis due to disseminated intravascular coagulation and dermal vascular thrombosis that leads to purpura and tissue necrosis. Various therapies have been used to arrest the progression of this disease, however, there is no established treatment because of the variety of underlying causes. We herein present an adult case of PF associated with leukocytoclastic vasculitis triggered by antibiotic (levofloxacin) intake. Read More

    [Uncommon cutaneous presentation of visceral Leishmaniasis associated with HIV].
    Ann Dermatol Venereol 2016 Dec 11;143(12):841-845. Epub 2016 Oct 11.
    Service de maladies infectieuses et tropicales, CHU de Poitiers, 2, rue de la Milétrie, 86021 Poitiers, France.
    Background: Visceral leishmaniasis is not normally expressed in skin. Herein, we describe the case of an HIV-positive patient who developed two unusual skin manifestations during an episode of visceral leishmaniasis.

    Patients And Methods: A 48-year-old female patient consulted initially for infiltrated purpura of all four limbs. Read More

    Upper Gastrointestinal Bleeding as the First Manifestation of Wegener's Granulomatosis.
    Middle East J Dig Dis 2016 Jul;8(3):235-239
    Department of pathology, Al-Zahra Hospital, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
    Wegener's granulomatosis is an uncommon inflammatory disease that manifests as vasculitis, granulomatosis, and necrosis. It usually involves the upper and lower respiratory tracts and kidneys. Although it may essentially involve any organ, gastrointestinal (GI) involvement is notably uncommon. Read More

    A not-so-sweet diagnosis - leukocytoclastic vasculitis masquerading as squamous cell carcinoma.
    Int Wound J 2016 Sep 29. Epub 2016 Sep 29.
    The Welsh Centre for Burns and Plastic Surgery, Morriston Hospital, Swansea, UK.
    Leukocytoclastic vasculitis (LCV) is a rare small-vessel vasculitis characterised by neutrophilic inflammation of post-capillary venules. Incidence varies from 3 to 4.5 per 100 000 people per year. Read More

    Vancomycin-associated Henoch-Schönlein purpura.
    J Infect Chemother 2017 Mar 25;23(3):180-184. Epub 2016 Sep 25.
    Division of Infectious Disease, Allegheny General Hospital, Allegheny Health Network, Pittsburgh, PA, USA.
    Intravenous vancomycin is a widely used antibiotics, but it causes different types of cutaneous hypersensitivity reactions, ranging from maculopapular rash, red-man syndrome, drug rash with eosinophilia and systemic symptoms, IgA bullous dermatosis, leukocytoclastic vasculitis, Stevens-Johnsons syndrome, to IgE-mediated anaphylaxis. We report an elderly patient with the end-stage renal disease presented with diffuse palpable purpura while receiving IV vancomycin therapy for methicillin-resistant Staphylococcus aureus septicemia. Histopathology of skin biopsy revealed perivascular infiltrates of leukocytoclastic debris with necrosis of the small-sized blood vessels. Read More

    Skin Findings in a Patient with Sjogren's Syndrome.
    Case Rep Rheumatol 2016 8;2016:4829459. Epub 2016 Sep 8.
    RUSH University Medical Center, Department of Rheumatology, 1725 West Harrison Street, Chicago, IL 60612, USA.
    Hypergammaglobulinemic purpura (HGP) is a syndrome constellating recurrent purpura, hypergammaglobulinemia, positive rheumatoid factor (RF), anti-Ro/La antibodies, and elevated erythrocyte sedimentation rate (ESR). We present a case of a 29-year-old female who was diagnosed with Sjogren's syndrome four years prior to presenting with rash on her lower extremities for a period of 6 months. Skin biopsy at the initial visit was consistent with leukocytoclastic vasculitis and was initiated on treatment for it. Read More

    Recurrent adult onset Henoch-Schonlein Purpura: a case report.
    Dermatol Online J 2016 08 15;22(8). Epub 2016 Aug 15.
    Department of Pathology, Weill Cornell Medicine, New York.
    Henoch-Schonlein purpura is an immunoglobulin A (IgA)-immune complex mediated leukocytoclastic vasculitis that classically manifests with palpable purpura, abdominal pain, arthritis, and hematuria or proteinuria. The condition is much more predominant in children (90% of cases) and commonly follows an upper respiratory infection. We present a case of recurrent Henoch-Schonlein purpura (HSP) complicated by nephritis in an adult female initially categorized as IgA nephropathy (IgAN). Read More

    Autoinflammatory associated vasculitis.
    Semin Arthritis Rheum 2016 Dec 20;46(3):367-371. Epub 2016 Jul 20.
    Rheumatology Unit, Bnai-Zion Medical Center, 47 Eliyahu Golomb St, Haifa, 33048 Israel.
    Autoinflammatory diseases are characterized by recurrent episodes of fever and localized or systemic inflammation and are caused by monogenic defects of innate immunity. The skin is commonly involved with various manifestations including erysipelas like rash and urticaria. Although vasculitis has been described in many autoinflammatory diseases, it has not been recognized as a characteristic feature of these diseases and autoinflammatory diseases are not listed as an etiology for vasculitis associated with a systemic disease in the 2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides. Read More

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