Evaluation of polymerase chain reaction in nerve biopsy specimens of patients with Hansen's disease.
- Vandana Tiwari,
- Kiranpreet Malhotra,
- Kainat Khan,
- Pradeep K Maurya,
- Ajai Kumar Singh,
- Anup Kumar Thacker,
- Nuzhat Husain,
- Dinkar Kulshreshtha
J Neurol Sci 2017 Sep 27;380:187-190. Epub 2017 Jul 27.
Department of Neurology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India. Electronic address:
Background: Pure neuritic variety of leprosy (PNL) presents as peripheral neuropathy with absent skin lesions and negative skin smears. Diagnosing PNL is an uphill task as most of these patients have nonspecific changes on nerve biopsy. In such circumstances, additional molecular diagnostic tools like polymerase chain reaction (PCR) has proven to be useful in diagnosing leprosy. Read More