Revisiting primary neural leprosy: Clinical, serological, molecular, and neurophysiological aspects.
- Diogo Fernandes Dos Santos,
- Matheus Rocha Mendonça,
- Douglas Eulálio Antunes,
- Elaine Fávaro Pípi Sabino,
- Raquel Campos Pereira,
- Luiz Ricardo Goulart,
- Isabela Maria Bernardes Goulart
PLoS Negl Trop Dis 2017 Nov 27;11(11):e0006086. Epub 2017 Nov 27.
National Reference Center for Sanitary Dermatology and Leprosy, Clinics' Hospital, School of Medicine, Federal University of Uberlândia (UFU), Uberlândia, MG, Brazil.
Background: Leprosy neuropathy is considered the most common peripheral neuropathy of infectious etiology worldwide, representing a public health problem. Clinical diagnosis of primary neural leprosy (PNL) is challenging, since no skin lesions are found and the slit skin smear bacilloscopy is negative. However, there are still controversial concepts regarding the primary-neural versus pure-neural leprosy definition, which will be explored by using multiple clinical-laboratory analyses in this study. Read More