Biochem Biophys Res Commun 2018 Apr 16. Epub 2018 Apr 16.
Pharmaceutical & Healthcare Research Laboratories, FUJIFILM Inc., Kanagawa, Japan.
The cause of hyperpigmentation, such as solar lentigo and seborrheic keratosis, is the excessive accumulation of melanin pigments in the epidermal basal layer. Melanin pigments are synthesized in the melanosomes, which are specific organelles produced by melanocytes in the basal layer. Melanosomes containing melanin pigments are transported to the neighboring keratinocytes. Read More