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    Torsion of pedunculated subserous uterine leiomyoma: A rare complication of a common disease.
    Taiwan J Obstet Gynecol 2018 Apr;57(2):300-303
    Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, Taiwan; Graduate Institute of Oncology, College of Medicine, National Taiwan University, Taipei, Taiwan; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan. Electronic address:
    Objective: To evaluate the clinical presentations, diagnosis, management, and outcomes of torsion of the pedunculated subserous uterine leiomyoma.

    Materials And Methods: We retrospectively reviewed medical records of patients with subserous uterine leiomyomas undergoing surgeries at National Taiwan University Hospital from January 2001 to December 2015.

    Results: Five cases of torsion of pedunculated subserous uterine leiomyoma were identified. Read More

    Molecular biomarkers for uterine leiomyosarcoma and endometrial stromal sarcoma.
    Cancer Sci 2018 Apr 16. Epub 2018 Apr 16.
    Department of Obstetrics and Gynecology, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.
    Uterine leiomyosarcoma (u{\hyphen}LMS) and endometrial stromal sarcoma (ESS) are among the most frequent soft tissue sarcomas, which, in adults, lead to fatal lung metastases and have an extremely poor prognosis. Due to their rarity and heterogeneity, there are no suitable biomarkers for diagnosis and prognosis, though some biomarker candidates have appeared. Recently, The Cancer Genome Atlas (TCGA) projects dealing with u{\hyphen}LMS confirmed mutations and deletions in RB1, TP53, and PTEN. Read More

    Rectal leiomyoma, a rare entity.
    Clin Pract 2018 Mar 21;8(2):1053. Epub 2018 Mar 21.
    Department of Internal Medicine, SBH Health System, Bronx, NY, USA.
    Rectal tumors are often encountered as an incidental finding on screening colonoscopy. As per the World Health Organization, they are categorized according to their histologic appearance. These include epithelial tumors, mesenchymal tumors and lymphomas. Read More

    Enhanced Wound Healing after Leiomyoma Enucleation.
    World J Plast Surg 2018 Jan;7(1):122-127
    Health Policy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
    Leiomyoma is a rare esophageal tumor that constitutes less than 1% of esophageal malignancies. It should be removed when diagnosed even if asymptomatic. This study presents two cases of esophageal leiomyoma in 38 and 62 years old men who presented with dysphagia and evaluated for diagnosis and location of related tumors. Read More

    Regulation of Cell Cycle Regulatory Proteins by MicroRNAs in Uterine Leiomyoma.
    Reprod Sci 2018 Jan 1:1933719118768692. Epub 2018 Jan 1.
    1 Department of Obstetrics and Gynecology, Harbor-UCLA Medical Center and LA-Biomed Research Institute, Torrance, CA, USA.
    The objective of this study was to determine whether miR-93, miR-29c, and miR-200c, which we previously reported to be downregulated in leiomyomas, target cell cycle regulatory proteins that influence cell proliferation. Based on TargetScan algorithm 3 cell cycle regulatory proteins namely, E2F transcription factor 1 (E2F1), Cyclin D1 (CCND1) and CDK2 which were predicted to be targets of these miRNAs were  further analyzed. In 30 hysterectomy specimens, we found the expression of E2F1 and CCND1 messenger RNA (mRNA) was increased in leiomyoma as compared to matched myometrium, with no significant changes in CDK2 mRNA levels. Read More

    [Urethral leiomyoma].
    Urologiia 2018 Mar(1):129-133
    Nizhny Novgorod State Medical Academy of Minzdrav of Russia, Nizhny Novgorod, Russia.
    In urology practice, leiomyoma of the urinary bladder is considered a rare tumor. Urethral leiomyoma is even more unusual. This article is a case report of a very rare benign tumor originating from the smooth muscles of the urethra causing obstructive voiding in a woman. Read More

    Identification of Leiomyoma Cell Sheets in Peritoneal Washings Retrieved by an Intraoperative Red Blood Cell Salvage Device during Laparoscopic-Assisted Myomectomy with in-Bag Manual Tissue Extraction: a Pilot Study.
    J Minim Invasive Gynecol 2018 Apr 6. Epub 2018 Apr 6.
    Department of Diagnostic Pathology, Gifu Prefectural Tajimi Hospital, Tajimi, Gifu, Japan.
    Study Objective: To examine whether peritoneal washings during laparoscopic-assisted myomectomy with in-bag manual tissue extraction can contain spilled leiomyoma cell sheets.

    Design: Retrospective observational study (Canadian Task Force classification II-2).

    Setting: Departments of Obstetrics and Gynecology, and Diagnostic Pathology at a general hospital PATIENTS: Twenty-four women. Read More

    PROGINS Polymorphism of the Progesterone Receptor Gene and the Susceptibility to Uterine Leiomyomas: A Systematic Review and Meta-Analysis.
    Genet Test Mol Biomarkers 2018 Apr 9. Epub 2018 Apr 9.
    4 Department of Collective Health, Faculdade de Medicina do ABC, Human Reproduction and Genetics Center , Santo André, Brazil .
    Aims: Steroid hormones play a central role in modulating the growth of uterine leiomyoma, and several studies have suggested that polymorphisms in genes encoding these hormones and their receptors may be risk factors for developing the disease. Progesterone is a potent antagonist of estrogen-induced proliferation in the endometrium, and the PROGINS polymorphisms have been associated with leiomyoma, but the results are inconsistent. In this study, we aimed to investigate the possible associations between the PROGINS polymorphisms and uterine leiomyoma. Read More

    Clinicopathologic Features and Genetic Alterations of a Primary Osteosarcoma of the Uterine Corpus.
    Int J Gynecol Pathol 2018 Apr 6. Epub 2018 Apr 6.
    Department of Pathology (G.Z., A.R., C.L., A.B., A.P., L.H., E.M., R.V., D.X.) Department of Gynecology and Obstetrics (R.L.S, R.V.), The Johns Hopkins Medical Institute, Baltimore, Maryland.
    Primary osteosarcoma (OS) of the uterus is distinctly rare. We report a case of primary uterine OS with pulmonary metastasis in a 74-yr-old woman. Histopathologic features of the uterine tumor were in keeping with a pure chondroblastic OS composed of neoplastic cells with osteoblastic/chondroblastic differentiation and neoplastic bone formation. Read More

    Weight change and risk of uterine leiomyomas: Korea Nurses' Health Study.
    Curr Med Res Opin 2018 Apr 6:1-13. Epub 2018 Apr 6.
    b Department of Food and Nutrition , College of Human Ecology, Seoul National University , Seoul , Republic of Korea.
    Objective: We examined the associations between anthropometric measures and uterine leiomyomas.

    Methods: We included a total of 5,062 women (median age of 35.5 years) who had experienced pregnancy and, of these women, 210 reported a diagnosis of uterine leiomyomas within the past 2 years in the Korea Nurses' Health Study. Read More

    Expression and prognostic value of lactate dehydrogenase-A and -D subunits in human uterine myoma and uterine sarcoma.
    Medicine (Baltimore) 2018 Apr;97(14):e0268
    Department of Gynecology, the Affiliated Hospital of Qingdao University, 1677 Wutai Mountain Road, Huangdao District, Qingdao City, Shandong Province, China.
    Objective: This study aimed to determine the expression of lactate dehydrogenase (LDH)-A and LDH-D in patients with uterine myoma, cellular leiomyoma (CLM), and uterine sarcoma and to evaluate their prognostic significance.

    Methods: Protein expression levels of LDH-A and LDH-D were determined in tissue samples from 86 patients (26 uterine myoma, 10 CLM, 50 uterine sarcoma) by immunohistochemistry and their associations with clinicopathologic parameters and outcomes were analyzed in patients with uterine sarcoma.

    Results: The positivity rates for LDH-A and LDH-D were significantly higher in patients with uterine sarcoma compared with those with uterine myoma or CLM (P < . Read More

    Spontaneous subserosal venous rupture overlying a uterine leiomyoma in a young woman.
    Pan Afr Med J 2017 7;28:205. Epub 2017 Nov 7.
    Department "A" of Gynecology and Obstetrics, Center of Maternity and Neonatology of Tunis, Tunisia.
    Uterine leiomyomas are very common tumors found in women. Rupture of veins on the surface of uterine leiomyoma is an unusual source of hemoperitoneum. It is an extremely uncommon gynaecological cause of hemoperitoneum. Read More

    Improvement in health utility after transcervical radiofrequency ablation of uterine fibroids with the sonata system: Health utility after radiofrequency ablation.
    Eur J Obstet Gynecol Reprod Biol 2018 Mar 27;224:175-180. Epub 2018 Mar 27.
    Decision Driver Analytics, United States.
    Objectives: To establish the improvement in patient health utilities following treatment of symptomatic uterine fibroids with the Sonata™ System.

    Study Design: A prospective, single-arm trial was conducted in which 49 women in the United Kingdom, Netherlands and Mexico with fibroids were treated with transcervical, intrauterine ultrasound- guided radiofrequency ablation. The EQ-5D-3L system was utilized to collect patient health status at baseline, 3, 6, and, 12 months post-procedure. Read More

    Female paraurethral leiomyoma successfully excised through a vaginal approach: A case report.
    J Obstet Gynaecol Res 2018 Apr 2. Epub 2018 Apr 2.
    Department of Obstetrics and Gynecology, Mitoyo General Hospital, Kagawa, Japan.
    Paraurethral leiomyomas are extremely rare, and few cases have been reported in the literature. Because of the rarity of the disease and its anatomical complexity, diagnosis and management is challenging for clinicians. Here, we herein report the case of a 50-year-old woman who complained of a protruding mass at the urethral opening. Read More

    Primary mediastinal leiomyoma: a rare case report and literature review.
    J Thorac Dis 2018 Feb;10(2):E116-E119
    Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
    Primary mediastinal leiomyomas are extremely rare, its etiology unknown, and up to the present has only been described in a few cases in the English literature. In this case report, we describe a 3-year-old girl with asymptomatic left upper quadrant abdominal mass. Chest computed tomography demonstrated a giant solid mass in the anterior mediastinum, which extended to the right hemi-thorax and left upper quadrant abdomen. Read More

    Robotic- Assisted Laparoscopic Cervicovaginal Myomectomy.
    J Minim Invasive Gynecol 2018 Mar 28. Epub 2018 Mar 28.
    Nezhat Surgery for Gynecology/Oncology, Weill Cornell Medical College of Cornell University, Stony Brook University School of Medicine, Minimally Invasive Gynecologic Surgery and Robotics| NYU Winthrop Hospital. Electronic address:
    Study Objective: To illustrate a robotic assisted laparoscopic resection for the cervicovaginal myomectomy.

    Design: Step-wise instruction using video. Case report (Canadian Task Force classification III). Read More

    Missed diagnosis of esophageal leiomyoma leading to esophagectomy: a case report and review of literatures.
    J Thorac Dis 2018 Jan;10(1):E65-E69
    Department of Thoracic Surgery, West China Hospital of Sichuan University, Chengdu 610041, China.
    Leiomyomas are the most common benign esophageal neoplasm. About half of them were smaller than 5 cm and asymptomatic with a stable size for many years. Esophageal leiomyomas that excess than 5 cm in size may develop as a consequence of giant one at rapid growth rate. Read More

    Hereditary leiomyomatosis and renal cell cancer: Cutaneous lesions & atypical fibroids.
    Case Rep Womens Health 2017 Jul 23;15:31-34. Epub 2017 Jun 23.
    Division of Reproductive Endocrinology and Infertility, Boston, MA, USA.
    Objective: To report a diagnosis of hereditary leiomyomatosis and renal cell cancer (HLRCC) syndrome following initial presentation with multiple cutaneous lesions.

    Design: Case report.

    Design Classification: N/A. Read More

    Rare cause of fever of unknown origin: gastrointestinal stromal tumour.
    BMJ Case Rep 2018 Mar 28;2018. Epub 2018 Mar 28.
    Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
    A 44-year-old man presented with fever (low to high grade) for 2-month duration despite treatment with oral antibiotics and antipyretics. Further, enquiry did not yield any potentially explanatory clues to a diagnosis. Physical examination revealed only left axillary lymphadenopathy, but was otherwise unremarkable. Read More

    Laparoscopic hysterectomy for large uteri: Outcomes and techniques.
    J Minim Access Surg 2018 Mar 23. Epub 2018 Mar 23.
    Department of Gynecology, Apollo Health City, Hyderabad, Telangana, India.
    Aim: The aim of this study was to analyse our data of laparoscopic hysterectomy for large uteri (>16 weeks size) regarding their perioperative outcomes and possible factors for conversions to open surgery over 5 years. It also describes our techniques for the feasibility of performing such hysterectomies by the minimally invasive way.

    Materials And Methods: A five-year retrospective chart review was performed at the Minimal Access and Robotic Surgery Unit of the Department of Gynecology at Apollo Hospital, Hyderabad. Read More

    Uterine metastases originating from a pulmonary inflammatory myofibroblastic tumor.
    J Cancer Res Ther 2018 ;14(Supplement):S257-S259
    Department of Pathology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
    Pulmonary inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal tumor, and is considered an inflammatory pseudotumor. Here, we report of a 37-year-old woman with severe cough and stridor who was diagnosed with primary IMT of the lungs, with adenocarcinoma in situ based on the pathology in December 2012. A year later, transabdominal ultrasonography demonstrated a solid mass in the uterine wall that was initially diagnosed as a leiomyoma. Read More

    A statistical approach to Detect Intrinsically Disordered Proteins associated with Uterine Leiomyoma.
    Protein Pept Lett 2018 Mar 25. Epub 2018 Mar 25.
    Jadavpur University - Department of Computer Science and Engineering Kolkata. India.
    Background: Uterine Leiomyoma is mainly widespread non-malignant tumor. Around more than 80% woman have these particular tumor among them only 30% of them are detected. Integrin-ᵦ1 is one of the up regulated biomarkers during tumorgenesis which is also associated with structural disordered. Read More

    Management of a giant retroperitoneal leiomyoma: a case report.
    J Med Case Rep 2018 Mar 26;12(1):81. Epub 2018 Mar 26.
    General Surgery Department, Interior Security Forces Hospital, La Marsa, Tunisia.
    Background: Leiomyomas are benign tumors observed mainly in adult women. The retroperitoneum is a rare location for leiomyomas; almost 100 cases have been reported. Because retroperitoneal leiomyomas are paucisymptomatic and the tumor size at diagnosis is relatively large, surgical management is challenging. Read More

    Omega-3 fatty acids modulate the lipid profile, membrane architecture, and gene expression of leiomyoma cells.
    J Cell Physiol 2018 Mar 25. Epub 2018 Mar 25.
    Department of Experimental and Clinical Medicine, Università Politecnica delle Marche, Ancona, Italy.
    Uterine leiomyomas (fibroids or myomas) are the most common benign tumors of premenopausal women and new medical treatments are needed. This study aimed to determine the effects of omega-3 fatty acids on the lipid profile, membrane architecture and gene expression patterns of extracellular matrix components (collagen1A1, fibronectin, versican, or activin A), mechanical signaling (integrin β1, FAK, and AKAP13), sterol regulatory molecules (ABCG1, ABCA1, CAV1, and SREBF2), and mitochondrial enzyme (CYP11A1) in myometrial and leiomyoma cells. Myometrial tissues had a higher amount of arachidonic acid than leiomyoma tissues while leiomyoma tissues had a higher level of linoleic acid than myometrial tissues. Read More

    Screening of potential biomarkers in uterine leiomyomas disease via gene expression profiling analysis.
    Mol Med Rep 2018 May 15;17(5):6985-6996. Epub 2018 Mar 15.
    Department of Gynecology, Weifang People's Hospital, Weifang, Shandong 261041, P.R. China.
    The present study aimed to screen potential biomarkers for uterine leiomyomas disease, particularly target genes associated with the mediator of RNA polymerase II transcription subunit 12 (MED12) mutation. The microarray data of GSE30673, including 10 MED12 wild-type myometrium, 8 MED12 mutation leiomyoma and 2 MED12 wild-type leiomyoma samples, were downloaded from the Gene Expression Omnibus database. Compared with myometrium samples, differently-expressed genes (DEGs) in the MED12 mutation and wild-type leiomyoma samples were identified using the Limma package. Read More

    Current medical treatment of uterine fibroids.
    Obstet Gynecol Sci 2018 Mar 13;61(2):192-201. Epub 2018 Feb 13.
    Department of Obstetrics and Gynecology, Ewha Womans University College of Medicine, Seoul, Korea.
    Uterine fibroids (leiomyomas or myomas), benign monoclonal tumors, are the most common benign tumors in women. Heavy or prolonged menstrual bleeding, abnormal uterine bleeding, resultant anemia, pelvic pain, infertility, and/or recurrent pregnancy loss are generally associated with uterine fibroids. Although curative treatment of this tumor relies on surgical therapies, medical treatments are considered the first-line treatment to preserve fertility and avoid or delay surgery. Read More

    Paraurethral Leiomyoma as an Incidental Finding in Patient with Fibroid Uterus.
    Case Rep Obstet Gynecol 2018 7;2018:7042960. Epub 2018 Feb 7.
    Department of Urology, Montefiore Medical Center, 1250 Waters Place, Tower One, Suite 706, Bronx, NY 10461, USA.
    Paraurethral leiomyomas are rare benign fibromuscular tumors developing from urethra. The presenting symptoms are usually related to mass effect. We present a case of an incidental diagnosis of a paraurethral leiomyoma in a patient with a fibroid uterus. Read More

    Recurrent benign leiomyomas after total abdominal hysterectomy. Rich or poor estrogenic environment may lead to their recurrence?
    Int J Surg Case Rep 2018 22;44:191-193. Epub 2018 Feb 22.
    First Department of Obstetrics and Gynecology, University of Athens School of Medicine, Alexandra Hospital, Lourou and Vasilisis Sofias Avenue, 11528 Athens, Greece. Electronic address:
    Introduction: Benign metastasizing leiomyomas represent benign lesions consisted by leiomatosous tissue and could be observed in positions away from their usual localization, the human uterus. They commonly affect women that have undergone total hysterectomy. Approximately 100 similar cases have been reported in the literature, so the case we present is rare and reviewing the literature and needs to be reported. Read More

    Predictors of Long-Term NovaSure Endometrial Ablation Failure.
    J Minim Invasive Gynecol 2018 Mar 14. Epub 2018 Mar 14.
    Department of Obstetrics and Gynecology, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address:
    Study Objective: Endometrial ablation using the NovaSure system (Hologic Inc., Marlborough, MA) is 1 of the treatment options for heavy menstrual bleeding (HMB), which has a reported success rate of 81% to 90%. We aimed to identify predictors for NovaSure endometrial ablation failure. Read More

    Explorative Investigation of Whole-Lesion Histogram MRI Metrics for Differentiating Uterine Leiomyomas and Leiomyosarcomas.
    AJR Am J Roentgenol 2018 Mar 16:1-6. Epub 2018 Mar 16.
    1 Department of Radiology, Center for Biomedical Imaging, NYU School of Medicine, NYU Langone Medical Center, 660 First Ave, 3rd Fl, New York, NY 10016.
    Objective: The purpose of this study is to assess the utility of texture analysis of multiple MRI sequences for the differentiation of uterine leiomyomas and leiomyosarcomas.

    Materials And Methods: Seventeen leiomyosarcomas and 51 leiomyomas undergoing MRI before resection were included. Whole-lesion volumes of interest were placed on T2-weighted images, contrast-enhanced T1-weighted images, and apparent diffusion coefficient (ADC) maps. Read More

    One-stage surgery for removal of intravascular leiomyomatosis extending to right ventricle.
    Medicine (Baltimore) 2018 Mar;97(11):e0051
    Division of Cardiovascular Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan.
    Rationale: Intravascular leiomyomatosis (IVL) is a rare nonmalignant tumor that can be fatal if untreated.

    Patient Concerns: A 49-year-old nulliparous Asian woman who underwent hysterectomy and left salpingo-oophorectomy for multiple uterine leiomyomas 18 months prior presented complaining of intermittent palpitation and chest tightness for approximately 1 month. Echocardiography revealed a large mobile tumor mass extending from the inferior vena cava (IVC) to the right atrium that partially obstructed IVC flow and tricuspid inflow. Read More

    Predictors Of Adverse Outcome In Uterine Smooth Muscle Tumors Of Uncertain Malignant Potential (STUMP): A Clinico-pathological Analysis Of 22 Cases With A Proposal For The Inclusion Of Additional Histologic Parameters.
    Histopathology 2018 Mar 14. Epub 2018 Mar 14.
    Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital.
    Aims: Current WHO classification defines smooth muscle tumors of uncertain malignant potential (STUMP) as neoplasms that cannot be diagnosed reliably as benign or malignant using generally accepted criteria. This has led to application of various criteria sets; consequently, consistent and reliable outcome data is lacking. The aims of this study were: 1) to compare the frequency of adverse outcome in STUMP based on enhanced criteria; and 2) to perform failure analysis to identify feature(s) helpful in predicting outcome. Read More

    Synchronous gastric leiomyoma and intramuscular abdominal wall granular cell tumor with similar imaging features: A case report.
    Int J Surg Case Rep 2018 6;44:207-211. Epub 2018 Mar 6.
    Departments of Surgery, Jichi Medical University, Tochigi, Japan.
    Introduction: Gastric leiomyomas are benign mesenchymal tumors, comprising about 2.5% of gastric neoplasms, which can be difficult to differentiate from gastrointestinal stromal tumors which have malignant potential. Granular cell tumors in the abdominal wall are also rare. Read More

    Multiple Cutaneous and Uterine Leiomyomatosis with Renal Involvement: Report of a Rare Association.
    Indian J Dermatol 2018 Jan-Feb;63(1):73-75
    Department of Resident, AIIMS Jodhpur.
    Cutaneous leiomyomas (CLs) are uncommon benign smooth muscle tumours characterised by solitary or multiple painful nodules. Based on origin, three types are recognised, namely piloleiomyoma, dartoic leiomyoma, and angioleiomyoma, with piloleiomyomas being the commonest one. Reed's syndrome also known as multiple cutaneous and uterine leiomyomatosis (MCULs) is characterised by CLs in men and CLs and uterine fibroids in women. Read More

    Ulipristal acetate decreases transforming growth factor β3 serum and tumor tissue concentrations in patients with uterine fibroids.
    Fertil Steril 2018 Mar 7;109(3):501-507.e2. Epub 2018 Mar 7.
    First Department of Obstetrics and Gynecology, Center of Postgraduate Medical Education, Warsaw, Poland.
    Objective: To evaluate and compare transforming growth factor β3 (TGF-β3) serum concentration in patients with uterine fibroids (UFs) without hormone treatment, treated with ulipristal acetate (UPA), and controls; to evaluate TGF-β3 concentrations in UF tissue in patients without hormone treatment and those treated with UPA; and to evaluate the correlations of age and body mass index (BMI) with TGF-β3 serum and UF tissue levels between the groups.

    Design: Retrospective cohort study.

    Setting: University teaching hospital. Read More

    The incidence of unexpected uterine malignancy in women undergoing hysteroscopic myomectomy or polypectomy: A national population-based study.
    Eur J Obstet Gynecol Reprod Biol 2018 Mar 3;224:12-16. Epub 2018 Mar 3.
    Department of Obstetrics and Gynecology, Gyeongsang National University Changwon Hospital, School of Medicine, Gyeongsang National University, Changwon, Gyeongnam, Republic of Korea. Electronic address:
    Objective: The objective of this study was to investigate the incidence of unexpected uterine malignancy (UUM) diagnosed after hysteroscopic surgery for presumed submucosal leiomyomas or endometrial polyps.

    Study Design: From the Korean national health insurance database between January 1, 2009 and December 31, 2015, we analyzed inpatient sample data that were extracted by a stratified random sampling (gender and age) method. We extracted women with or without UUM that was diagnosed after hysteroscopic surgery using diagnosis codes and procedure codes. Read More

    Sterile Bronchopleural Fistula Following Surgical Removal of Primary Lung Leiomyoma Inducing Secondary Hypertrophic Osteoarthropathy.
    Am J Case Rep 2018 Mar 9;19:267-271. Epub 2018 Mar 9.
    College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
    BACKGROUND Leiomyomas are benign neoplasms of the smooth muscle. When found in the pulmonary system, a rare occurrence, leiomyomas can result in hypertrophic osteoarthropathy, or significant clubbing, associated with proliferation of long bone periosteum. Bronchopulmonary fistulas, or communications between the bronchial tree and pleural space, are an uncommon postoperative complication of pneumonectomies. Read More

    J Zoo Wildl Med 2018 Mar;49(1):79-85
    Reproductive lesions have been described in various nonhuman primate species, including rhesus macaques ( Macaca mulatta), cynomolgus macaques ( Macaca fascicularis), baboons ( Papio spp.), squirrel monkeys ( Saimiri sciureus), and chimpanzees ( Pan spp.); however, there are few publications describing reproductive disease and pathology in Japanese macaques ( Macaca fuscata). Read More

    False-positive radioiodine accumulation in a huge pelvic mass after thyroidectomy for papillary carcinoma, a case report from Syria.
    J Surg Case Rep 2018 Feb 28;2018(2):rjy028. Epub 2018 Feb 28.
    Faculty of Medicine, Surgery Department, Damascus University, Liver Surgery and Transplant Team in Al-Assad University Hospital, Damascus, Syria.
    Iodine has always been connected to thyroid gland, and the fact that thyroid tissue traps, organificates and stores iodine more than other tissues is well known, hence the use of radioiodine as a diagnostic and therapeutic tool for thyroid disorders. However, false-positive cases do occur. We present a case of a 34-year-old patient who underwent total thyroidectomy for papillary carcinoma. Read More

    [Benign metastasizing leiomyoma: An unusual cause of aggressive femoral bone tumor].
    Rev Med Interne 2018 Mar 1. Epub 2018 Mar 1.
    Service de médecine interne, hôpital Européen Georges-Pompidou, Assistance publique-Hôpitaux de Paris, 20, rue Leblanc, 75015 Paris, France; Université Paris Descartes, Sorbonne Paris Cité, 15, rue de l'école de médecine, 75006 Paris, France. Electronic address:
    Background: Benign metastasizing leiomyoma (BML) is a rare condition characterized by histologically benign "metastatic" smooth muscle tumors, which can affect women with history of uterine surgery. We report the case of a patient with bone metastases of BML.

    Case Report: A 78-year-old woman who had undergone uterine surgery six years before hospital admission, was diagnosed with large pulmonary and pleural metastases that necessitated surgical removal. Read More

    Laparoendoscopic Single-Site Supracervical Hysterectomy with Manual Morcellation: A Retrospective Study.
    J Minim Invasive Gynecol 2018 Mar 2. Epub 2018 Mar 2.
    Department of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address:
    Study Objective: To evaluate the feasibility, efficiency, and safety of manual morcellation in laparoendoscopic single-site (LESS) supracervical hysterectomy.

    Design: Retrospective study (Canadian Task Force classification II-2).

    Setting: A teaching hospital. Read More

    Size of uterine leiomyoma is a predictor for massive haemorrhage during caesarean delivery.
    Eur J Obstet Gynecol Reprod Biol 2018 Apr 21;223:60-63. Epub 2018 Feb 21.
    Department of Obstetrics and Gynecology, National Defense Medical College, Namiki 3-2, Tokorozawa, Saitama, 359-8513, Japan.
    Background: Uterine leiomyoma is a common benign tumour, and a risk factor for various complications during pregnancy and peripartum period. Peripartum haemorrhage is the most critical complication that can cause maternal death. Although the relationship of leiomyoma and peripartum haemorrhage has been indicated, little is known about the characteristics of leiomyoma as predictors for massive haemorrhage in caesarean delivery. Read More

    European Society of Urogenital Radiology (ESUR) Guidelines: MR Imaging of Leiomyomas.
    Eur Radiol 2018 Feb 28. Epub 2018 Feb 28.
    Department of Radiology, Universitätsklinikum Salzburg, PMU; Müllner Hauptstr. 48, A-5020, Salzburg, Austria.
    Objective: The aim of the Female Pelvic Imaging Working Group of the European Society of Urogenital Radiology (ESUR) was to develop imaging guidelines for MR work-up in patients with known or suspected uterine leiomyomas.

    Methods: Guidelines for imaging uterine leiomyomas were defined based on a survey distributed to all members of the working group, an expert consensus meeting at European Congress of Radiology (ECR) 2017 and a critical review of the literature.

    Results: The 25 returned questionnaires as well as the expert consensus meeting have shown reasonable homogeneity of practice among institutions. Read More

    [Application of dynamic-contrast enhanced magnetic resonance pharmacokinetic models in differential diagnosis of cellular uterine leiomyoma].
    Zhejiang Da Xue Xue Bao Yi Xue Ban 2017 May;46(5):498-504
    Department of Radiology, Shaoxing Hospital of Zhejiang University, Shaoxing 312000, Zhejiang Province, China.
    Objective: To assess the application of the dynamic-contrast enhanced magnetic resonance imaging(DCE-MRI)pharmacokinetics models in differential diagnosis of cellular uterine leiomyoma.

    Methods: Sixty four patients with uterine leiomyoma confirmed by surgery and pathology were enrolled in the study between September 2015 and September 2016, including 30 cases of classical leiomyoma, 13 cases of cellular leiomyoma and 21 cases of degenerative leiomyoma. All patients underwent DCE-MRI before surgery. Read More

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