121,164 results match your criteria Legal Medicine [Journal]


Inflammation and oxidative stress are key mediators in AKB48-induced neurotoxicity in vitro.

Toxicol In Vitro 2018 Dec 11. Epub 2018 Dec 11.

Istanbul University, Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Beyazıt, 34116 Istanbul, Turkey.

Synthetic cannabinoids were introduced into market in early 2000s; since these "legal highs" are dramatically popular among youth, it becomes a deadly problem. Synthetic cannabinoids have high affinity to cannabinoid receptors; leading to various clinical symptoms. AKB48 (Apinaca) has been classified as a third-generation synthetic cannabinoid for the first time in 2014. Read More

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December 2018
1 Read

Counterfactual Thinking, Causation, and Covariation in Mock Juror Assessments of Negligence: Twenty-Five Years Later.

Authors:
Jason A Cantone

Psychol Rep 2018 Dec 14:33294118816945. Epub 2018 Dec 14.

George Mason University, Fairfax, VA, USA.

In the past three decades, researchers have examined counterfactual thinking and causation in decision making. However, little work has applied these findings to trial settings. The present research examined two conflicting theories regarding counterfactual thinking and causation to elaborate on earlier work examining counterfactual thinking in negligence law cases. Read More

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December 2018

The impact of anti-vascular endothelial growth factor agents on visual impairment/blindness prevention in patients with diabetic macular edema and on associated patient and caregiver burden in Japan.

J Med Econ 2018 Dec 14:1-28. Epub 2018 Dec 14.

e Market Access, Health Economics and Outcomes Research , Bayer Yakuhin, Ltd , Tokyo , Japan.

Aims: To estimate the impact of anti-vascular endothelial growth factor (VEGF) agents on visual impairment and blindness avoided in patients with diabetic macular edema (DME) and on associated patient and caregiver productivity loss in Japan.

Methods: We compared the impact of current care (estimated at 53.8% utilization of anti-VEGF agents using current data) with that of hypothetical care (characterized by a higher utilization of anti-VEGF agents [80. Read More

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December 2018
1 Read

Transgender inmates: A systems-based model for assessment and treatment planning.

Psychol Serv 2018 Dec 13. Epub 2018 Dec 13.

Correct Care Solutions.

Concepts of gender, gender roles, and gender norms have continuously adapted with the increased acceptance of diversity throughout the United States in recent decades. Although guidelines exist regarding competent assessment and treatment of transgender individuals, correctional environments place substantial restrictions and complications on this process. Recent legal cases have increased public awareness of such cases, including challenges to the status quo of which responsibilities fall under the purview of correctional systems. Read More

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December 2018

[CRIMINAL RESPONSIBILITY OF MEDICAL AND ITS CASE LAW EVOLUTION. LEGAL AND ECONOMIC PROFILES].

Authors:
Antonio Capasso

G Ital Nefrol 2018 Dec;35(6)

Dottore in giurisprudenza, Cultore della materia Università Federico II Napoli.

The article deals with the regulatory and jurisprudential evolution of medical criminal responsibility from the 70s to the Gelli-Bianco law of 2017. Subsequently it winds through the contribution of the last important judgments of the subject up to the decisions of the Supreme Court with United Sections of 2018, finally to conclude with an economic analysis on the increasement of the legal disputes registered in recent years. Read More

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December 2018

Survey on the status of teledermatology in Austria.

J Dtsch Dermatol Ges 2018 Dec 14. Epub 2018 Dec 14.

Department of Dermatology, Graz Medical University, Graz, Austria.

Background: The use of digital communication media is becoming increasingly important, with the primary aim of improving both treatment quality and patients' quality of life. In an effort to optimize telemedicine in the field of dermatology, we conducted a survey among dermatologists in Austria.

Methods: Statistical analysis of a questionnaire that was developed by a working group and sent to 769 Austrian dermatologists. Read More

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December 2018

From democratic participation to civic resistance: the loss of institutional trust as an outcome of activism in the refugee solidarity movement.

Authors:
Jonas Toubøl

Br J Sociol 2018 Dec 12. Epub 2018 Dec 12.

Adding to the literature on non-institutional political action and trust, this article argues that the loss of institutional trust is not only a cause but also an outcome of political activism. Studying the Danish refugee solidarity movement in a mixed-methods research design including survey and qualitative interview data, the article shows that three kinds of activism - political activism, humanitarian activity, and civil disobedience - relate differently to the loss of trust in the institutions of the Parliament, the legal system, and the police. Political activism primarily affects a loss of trust in the Parliament due to low external efficacy and a closed political opportunity structure. Read More

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December 2018

Tramadol dispensing patterns and trends in Canada, 2007-2016.

Pharmacoepidemiol Drug Saf 2018 Dec 12. Epub 2018 Dec 12.

Centre for Applied Research in Mental Health and Addiction, Faculty of Health Sciences, Simon Fraser University, Vancouver, Canada.

Purpose: Opioid use and associated mortality and morbidity have substantially increased in Canada, which recent interventions have aimed to reduce. Tramadol is an atypical prescription-only (but unscheduled under Canada's narcotics law) opioid analgesic and not subject to controls for other (eg, strong) opioids. Given experiences in different jurisdictions, tramadol may have been increasingly dispensed as a "substitute" drug during a period with increasingly restrictive controls for other (scheduled) opioids. Read More

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December 2018

The Effects of Victimization and Fear of Crime on the Legal Socialization of Young Adolescents in São Paulo, Brazil.

Int J Offender Ther Comp Criminol 2018 Dec 14:306624X18818810. Epub 2018 Dec 14.

2 University of São Paulo, Brazil.

It is important to understand how young adolescents come to view authorities during formative years. Experiencing, witnessing, and fearing victimization have been linked to the process of legal socialization and subsequent attitudes and behavior. In addition, procedural justice may influence adolescent perceptions of fairness of the authorities. Read More

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December 2018

Cannabis Oil in an Irish Children’s Critical Care Unit

Ir Med J 2018 09 10;111(8):807. Epub 2018 Sep 10.

Department of Paediatric Anaesthesia, Critical Care Medicine and Pain Medicine, Our Lady’s Children’s Hospital, Crumlin, Dublin 12.

Aims We present a case of a five-year-old female admitted postoperatively to the Paediatric Critical Care Unit with a history of refractory seizures for which her parents were administering cannabis oil. Methods We discuss the issues surrounding cannabis prescription in Ireland and the role of parental autonomy in medication selection and administration. Results An administration regime was agreed upon following discussion with the child’s parents. Read More

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September 2018

Pursuing Social Justice through Public Health: Gender and Sexual Diversity Activism in Malawi.

Crit Afr Stud 2017 15;9(1):71-90. Epub 2017 Feb 15.

The Center for Medicine, Health, and Society, Vanderbilt University, PMB #351665, 2301 Vanderbilt Pl., Nashville, TN 37235-1665 USA, Telephone: +1-615-322-0718.

African lesbian, gay, bisexual, transgender, intersex, and queer (LGBTIQ) organizations face various strategic dilemmas in contexts characterized by political hostility to gender and sexual dissidents. In Malawi, one such context, we examine how an LGBTIQ social movement organization (SMO) in Malawi, the Centre for the Development of People (CEDEP), navigated one particular strategic dilemma-the dilemma of whether to adopt a less politicized public-health approach or a more nimble, grassroots-oriented, and social-justice approach to their advocacy work-and the consequences of the organization's strategic decisions. Scholars interpret these approaches as signifying differential political engagement among organizations, with the social-justice approach indicating political engagement and the public-health approach signaling political disengagement. Read More

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February 2017

Assessment of Dioxin and Furan Emission Levels and Management Practices in Addis Ababa, Ethiopia.

J Health Pollut 2017 Sep 7;7(15):85-94. Epub 2017 Sep 7.

Environment and Climate Change Management (ECCM) Department, Ethiopian Civil Service University, P.O.Box 26148; Addis Ababa, Ethiopia.

Introduction: An increase in population and related increased demand for health services, expansion of industries, and increasing transportation demands have increased the emission of dioxin and furan persistent organic pollutants (POPs) in Addis Ababa, Ethiopia.

Objective: This study aimed to identify sources of dioxin and furan emissions, quantify their release into various environmental medias and assess related management practices.

Methods: The standard United Nations Environmental Programme (UNEP) (2005) toolkit guide and default emission factor were used to identify the main anthropogenic sources and to quantify the amount of released dioxin and furan. Read More

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September 2017

More interdisciplinary research is needed in forensic medicine.

Forensic Sci Med Pathol 2018 Dec 13. Epub 2018 Dec 13.

Charité - Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Legal Medicine and Forensic Sciences, Berlin, Germany.

Forensic routine consists of more than just the classical legal medicine described in textbooks. It is often crucial to answer forensic questions that involve numerous interfaces with other medical disciplines. These interdisciplinary questions that arise in routine autopsy proceedures can also be addressed scientifically, despite decreasing autopsy numbers. Read More

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December 2018

Cardiac Involvement by Yellow Fever(from the PROVAR+ Study).

Am J Cardiol 2018 Dec 4. Epub 2018 Dec 4.

Serviço de Cardiologia e Cirurgia Cardiovascular e Centro de Telessaúde do Hospital das Clínicas da UFMG, Belo Horizonte, Minas Gerais, Brazil; Departamento de Clínica Médica, Faculdade de Medicina da Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil. Electronic address:

Incidence of Yellow Fever (YF) has increased in Brazil, and cardiac findings such as bradyarrhythmias and conduction abnormalities have been described. We aimed to perform a comprehensive cardiac evaluation of patients with YF, and to assess the association between cardiac involvement and disease severity. Patients hospitalized with YF from February to March 2018 underwent clinical and laboratory evaluation, focused bedside echocardiography (GE Vivid IQ), electrocardiogram and, in case of alterations, 24-hours Holter. Read More

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December 2018
1 Read

Increased Use of Medical Marijuana: Skepticism vs. Evidence.

Authors:
Jeannette Y Wick

Consult Pharm 2018 Dec;33(12):680-689

The use of medical marijuana-both the psychoactive tetrahydrocannabinol and its nonpsychoactive relative cannabidiol-is a growing practice in facilities served by senior care pharmacists. Currently, 30 states have approved its use under a variety of different regulations and for a number of conditions. Its use is bolstered by a growing number of Americans who support legalization of cannabis. Read More

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December 2018

The patient-psychologist relationship and informed consent in neuropsychological evaluations.

Clin Neuropsychol 2018 Dec 14:1-28. Epub 2018 Dec 14.

a Independent Practice , Beaverton , OR , USA.

Objective: To discuss specific issues regarding consent for neuropsychological evaluation and the patient-psychologist relationship within the context of the Ethics Code of the American Psychological Association and relevant literature.

Method: The author makes recommendations based on the Ethics Code and published sources. This article is advisory and does not prescribe ethical practice. Read More

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December 2018

High-Frequency Heating Extraction Method for Sensitive Drug Analysis in Human Nails.

Molecules 2018 Dec 7;23(12). Epub 2018 Dec 7.

Department of Legal Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan.

A simple, sensitive, and rapid extraction method based on high-frequency (H-F) heating was developed for drug analysis in human nails. A human nail was placed in a glass tube with an extraction solvent (methanol and 0.1% formic acid; 7:3, /), and a ferromagnetic alloy (pyrofoil) was wrapped in a spiral around the glass tube. Read More

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December 2018

Transition of a Mallory-Weiss syndrome to a Boerhaave syndrome confirmed by anamnestic, necroscopic, and autopsy data: A case report.

Medicine (Baltimore) 2018 Dec;97(49):e13191

Department of Legal and Forensic Medicine, University of Genova, Genova.

Rationale: Spontaneous esophageal rupture (Boerhaave syndrome) is a rare, though frequently fatal, event. It is generally caused by a sudden increase in pressure inside the esophagus. In some cases, full-thickness perforations of the esophagus may develop from previous lesions that initially involve only the esophageal mucosa (Mallory-Weiss syndrome) and which, following further triggering events, give rise to a transmural lesion. Read More

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December 2018
4 Reads

Barriers and opportunities to improve the foundations for high-quality healthcare in the Mexican Health System.

Health Policy Plan 2018 Dec 12. Epub 2018 Dec 12.

Institute of Social Research, National Autonomous University of Mexico, Mexico City, Mexico.

This study aimed to describe the foundations for quality of care (QoC) in the Mexican public health sector and identify barriers to quality evaluation and improvement from the perspective of the QoC leaders of the main public health sector institutions: Ministry of Health (MoH), the Mexican Institute of Social Security (IMSS) and the Institute of Social Security of State Workers (ISSSTE). We administered a semi-structured online questionnaire that gathered information on foundations (governance, health workforce, platforms, tools and population), evaluation and improvement activities for QoC; 320 leaders from MoH, IMSS and ISSSTE participated. We used thematic content and descriptive analyses to analyse the data. Read More

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December 2018

Protecting the Rights of Children with Intersex Conditions from Nonconsensual Gender-Conforming Medical Interventions: The View from Europe.

Med Law Rev 2018 Dec 13. Epub 2018 Dec 13.

Faculty of Law, Lund University, Lund, Sweden.

Nonconsensual gender-conforming interventions on children with intersex conditions have recently come under sharp criticism from human rights authorities within the United Nations, the Council of Europe, and the European Union, which have identified these interventions as violating children's rights to bodily integrity, privacy, and protection from violence, torture, and degrading treatment. Responding largely to requests for intervention from nongovernmental organizations, these authorities have called upon nations to reform their legal frameworks, both to prevent these rights violations and to redress them. To date, however, few nations have endeavored to prohibit nonconsensual gender-conforming procedures on children with intersex conditions, and none have enacted significant reforms of their frameworks to redress rights violations. Read More

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December 2018

Use of the Randox Evidence Investigator immunoassay system for near-body drug screening during post-mortem examination in 261 forensic cases.

Forensic Sci Int 2018 Nov 26;294:211-215. Epub 2018 Nov 26.

Department of Archaeology, Anthropology & Forensic Science, Bournemouth University, Fern Barrow, Poole, Dorset, BH12 5BB, UK. Electronic address:

Background: This paper describes the performance of four Randox drug arrays, designed for whole blood, for the near-body analysis of drugs in a range of post-mortem body specimens.

Methods: Liver, psoas muscle, femoral blood, vitreous humor and urine from 261 post-mortem cases were screened in the mortuary and results were obtained within the time taken to complete a post-mortem. Specimens were screened for the presence of amfetamine, barbiturates, benzodiazepines, benzoylecgonine, buprenorphine, cannabinoids, dextropropoxyphene, fentanyl, ketamine, lysergide, methadone, metamfetamine, methaqualone, 3,4-methylenedioxymetamfetamine, opioids, paracetamol, phencyclidine, salicylate, salicylic acid, zaleplon, zopiclone and zolpidem using the DOA I, DOA I+, DOA II and Custom arrays. Read More

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November 2018

Regulatory and Evidence Requirements and the Changing Landscape in Regulation for Marketing Authorisation.

Recent Results Cancer Res 2019 ;213:169-187

European Medicines Agency, 30 Churchill Place, Canary Wharf, London, UK.

In this chapter, we describe the changing landscape of the EU pharmaceutical legislation concerning regulation and evidence requirements for marketing authorisation. First, we describe the legal requirements for marketing authorisation and the development of EU pharmaceutical legislation and the concept of risk-benefit balance. Second, we describe special types of authorisation, such as conditional approval and approval under exceptional circumstances, and special provisions such as incentives for orphan medicinal products and paediatric investigational plans. Read More

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January 2019

Cannabinoids: Potential Role in Inflammatory and Neoplastic Skin Diseases.

Am J Clin Dermatol 2018 Dec 12. Epub 2018 Dec 12.

George Washington University School of Medicine and Health Sciences, Washington, DC, USA.

The endocannabinoid system is a complex and nearly ubiquitous network of endogenous ligands, enzymes, and receptors that can also be stimulated by exogenous compounds such as those derived from the marijuana plant, Cannabis sativa. Recent data have shown that the endocannabinoid system is fully functional in the skin and is responsible for maintaining many aspects of skin homeostasis, such as proliferation, differentiation, and release of inflammatory mediators. Because of its role in regulating these key processes, the endocannabinoid system has been studied for its modulating effects on both inflammatory disorders of the skin and skin cancer. Read More

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December 2018

Corrigendum: Is There a Conjunction Fallacy in Legal Probabilistic Decision Making?

Front Psychol 2018 27;9:2281. Epub 2018 Nov 27.

Department of Psychology, City, University of London, London, United Kingdom.

[This corrects the article DOI: 10.3389/fpsyg.2018. Read More

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November 2018

Disgust, stigma, and the politics of abortion.

Authors:
Anuradha Kumar

Fem Psychol 2018 Nov 19;28(4):530-538. Epub 2018 Apr 19.

Ipas, USA.

Despite the growing body of research on the emotion of disgust - including its relationship to political ideology, moral judgment, matters of sex and sexuality, and death - the global reproductive rights movement has paid relatively little attention to the role disgust plays in the debate over abortion. By focusing on the right of a woman to make her own decision about an unwanted pregnancy, the pro-choice community has allowed anti-choice groups to define and frame the abortion procedure, abortion providers, and women who have abortions in terms associated with disgust. This commentary encourages further examination of what triggers disgust, its measurement, and ways of mitigating it, which could be useful for reducing abortion stigma, in future legal cases and in abortion research, advocacy, and communications. Read More

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November 2018

[Medical team's struggle with financial abuse in the corresponding -Limitation of the adult guardianship system: A case report].

Nihon Ronen Igakkai Zasshi 2018 ;55(4):663-667

Department of Internal Medicine, Nagoya City Kousei-in.

Upon diagnosis of dementia, a 93-year-old woman was unable to manage her finances. Her nephew illegally spent her money, which was considered as financial abuse.The public office forcibly admitted her to our hospital as a legal measure. Read More

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January 2018

Big data and black-box medical algorithms.

Sci Transl Med 2018 Dec;10(471)

University of Michigan Law School, 921 Legal Research, 801 Monroe St., Ann Arbor, MI 48109, USA.

New machine-learning techniques entering medicine present challenges in validation, regulation, and integration into practice. Read More

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December 2018

[Regulatory requirements; What steps must be taken before starting a biomedical research study?]

Semergen 2018 Dec 9. Epub 2018 Dec 9.

Centro de Concepción Arenal, Gerencia de Gestión Integrada de Santiago de Compostela, Servicio Galego de Saúde, Santiago de Compostela (A Coruña), España. Electronic address:

Studies of research with human beings, their biological specimens, or their personal data in the field of biomedicine have been subject to regulation since the middle of the last century. Initially a regulation based on recommendations such as the Nuremberg Code, the Belmont Report or the first versions of the Declaration of Helsinki. All of them documents in which the principles (autonomy, beneficence, non-maleficence, and justice) were conceptualized, and that all researchers had to follow in the development of their research. Read More

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December 2018

Assessment of country policies affecting reproductive health for adolescents in the Philippines.

Reprod Health 2018 Dec 12;15(1):205. Epub 2018 Dec 12.

Department of Reproductive Health and Research/ Special Programme of Research, Development and Research Training in Human Reproduction, World Health Organization, Geneva, Switzerland.

Background: Adolescents in the Philippines face many legal, social and political barriers to access sexual and reproductive health (SRH) services, putting them at higher risk of unplanned pregnancy, abortion, sexually transmitted infections and HIV, and other health and development problems.

Objective: This study aims to evaluate whether current normative documents on SRH in the Philippines are in concurrence with adolescents' human rights principles using the World Health Organization (WHO) Guidance and Recommendations on ensuring human rights in the provision of contraceptive information and services.

Methods: The review focused on policies and normative guidance documents which included the national reproductive health law, its implementing rules and regulations, and the Supreme Court decisions on the law, and documents cited in the government's Adolescent and Youth Health Programme. Read More

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December 2018

Ethical issues in susceptibility genetic testing for late-onset neurodegenerative diseases.

Am J Med Genet B Neuropsychiatr Genet 2018 Dec 7. Epub 2018 Dec 7.

Department of Genetics & Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.

Genome-wide association studies have revolutionized our understanding of the genetic architecture of complex traits and diseases over the last decade. This knowledge is enabling clinicians, researchers, and direct-to-consumer genetics companies to conduct disease susceptibility testing based on powerful methods such as polygenic risk scoring. However, these technologies raise a set of complex ethical, legal, social, and policy considerations. Read More

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December 2018

Anabolic Androgenic Steroids: Searching New Molecular Biomarkers.

Front Pharmacol 2018 20;9:1321. Epub 2018 Nov 20.

Department of Medical, Surgical and Advanced Technologies "G.F. Ingrassia", University of Catania, Catania, Italy.

Even if anabolic androgenic steroid (AAS) abuse is clearly associated with a wide spectrum of collateral effects, adolescents and athletes frequently use a large group of synthetic derivatives of testosterone, both for aesthetic uses and for improving performance. Over the last few years, the development of MicroRNA (miRNA) technologies has become an essential part of research projects and their role as potential molecular biomarkers is being investigated by the scientific community. The circulating miRNAs detection as a diagnostic or prognostic tool for the diagnosis and treatment of several diseases is very useful, because with a minimal quantity of sample (peripheral blood), miRNAs are very sensitive. Read More

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November 2018

Mental capacity in Colombia: a comparison with the UK.

BJPsych Int 2018 Nov;15(4):85-88

Clinical Senior Lecturer in Mental Health, Ethics and Law, Wellcome Trust Senior Research Fellow, Institute of Psychiatry, Psychology and Neuroscience, King's College London.

Several international proclamations in the last decades have advocated for the dignity and autonomy of persons with mental disorders. Few discussions have been generated regarding the implication of this transition in low- and middle-income countries. The objective of this publication is to review how the concept of mental capacity has been defined in Colombian law. Read More

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November 2018

A European survey on the regulatory status for the estimation of the effective dose and the equivalent dose to the lens of the eye when radiation garments are used.

J Radiol Prot 2018 Nov 27. Epub 2018 Nov 27.

Institut de Tecniques Energetiques, Universidad Politecnica de Catalunya, Av Diagonal 647, Barcelona 08028, Barcelona, SPAIN.

Following the proposal of the ICRP for the reduction of dose limit for the lens of the eye which has been adopted by the International Atomic Energy Agency and the European Council a lot of concern has been raised about the implementation of proper dose monitoring methods defined in the national regulations and the harmonisation within European countries. EURADOS organised a survey at the end of 2017, through a web questionnaire, regarding the national dose monitoring regulations. The questions were related to: double dosimetry, algorithm for the estimation of the effective dose, methodology for the determination of the equivalent dose to the lens of the eye and structure of the national dose registry. Read More

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November 2018

Availability of legalized cannabis reduces demand for illegal cannabis among Canadian cannabis users: evidence from a behavioural economic substitution paradigm.

Can J Public Health 2018 Dec 6. Epub 2018 Dec 6.

Peter Boris Centre for Addictions Research, McMaster University and St. Joseph's Healthcare Hamilton, 100 West 5th St, Hamilton, ON, L8N 3K7, Canada.

In the context of cannabis legalization, an important question among clinicians, policymakers, and the public is whether availability of legal cannabis will significantly reduce consumption (demand) of illegal cannabis. Using paradigms from behavioural economics, we tested the prediction that legal cannabis would be an asymmetrical substitute for illegal cannabis, with legal cannabis operating as a superior commodity based on its regulated status. In a sample of 289 adult cannabis users in Ontario, we found evidence of substitutability for both legal and illegal cannabis, but significantly lower substitutability of illegal for legal cannabis, a pattern that was also present for price elasticity (α) and P. Read More

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December 2018

Understanding Subdural Collections in Pediatric Abusive Head Trauma.

AJNR Am J Neuroradiol 2018 Dec 6. Epub 2018 Dec 6.

Institute of Diagnostic and Interventional Radiology and Neuroradiology (M.L.H.), University Hospital Essen, Essen, Germany.

Life-threatening physical abuse of infants and toddlers is frequently correlated with head injuries. A common variant of the abusive head trauma is the shaken baby syndrome. The present review article sheds light on subdural collections in children with abusive head trauma and aims at providing a recent knowledge base for various medical disciplines involved in diagnostic procedures and legal proceedings. Read More

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December 2018

Medical Cannabis.

Mayo Clin Proc 2018 Dec;93(12):1842-1847

Division of General Internal Medicine, Mayo Clinic, Rochester, MN.

Medicolegal realities surrounding "medical marijuana" or "medical cannabis" are rapidly evolving in the United States. Clinicians are increasingly being asked by patients to share information about or certify them for medical cannabis. In order to engage in informed discussions with patients or be comfortable certifying them in states with medical cannabis laws, clinicians may benefit from an understanding of the current state of medical knowledge about medical cannabis. Read More

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December 2018

Species dilemma of musk deer (Moschus spp) in India: molecular data on cytochrome c oxidase I suggests distinct genetic lineage in Uttarakhand compared to other Moschus species.

Anim Biotechnol 2018 Dec 6:1-9. Epub 2018 Dec 6.

b Wildlife Institute of India , Dehradun , India.

Musk deer are of high conservation priority owing to poaching pressure because of its musk pod. Representation of musk deer status using genetics is poorly documented in India, and it is not confirmed as to how many species of musk deer are present. We characterize for the first time, the genetic diversity of musk deer from Uttarakhand using Cytochrome Oxidase sub-unit (COI) gene (486 bp) and compared with the data available for other species. Read More

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December 2018

Singing voice: acoustic parameters after vocal warm-up and cool-down.

Logoped Phoniatr Vocol 2018 Dec 6:1-9. Epub 2018 Dec 6.

a ENT Department , Policlinico S.M. alle Scotte , Siena , Italy.

Purpose: The aim of this study was to evaluate the effect of the vocal warm-up and cool-down on the singing voice through Fundamental Frequency (F0), Jitter, Shimmer and harmonics-to-noise ratio (HNR).

Methods: Thirty-two female singing students were recorded four times while uttering the vowel [a] for at least 5''. The first two recordings were collected before and after a vocal warm-up session and the last two before and after a vocal cool-down session. Read More

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December 2018

The effects of preconception examinations on birth defects: A population-based cohort Study in Dongguan City, China.

J Matern Fetal Neonatal Med 2018 Dec 6:1-141. Epub 2018 Dec 6.

a Maternal and Children Health Care Hospital of Donguan City , Dongcheng District , Dongguan , China.

Objective: To evaluate the effect of preconception examinations programs on the prevention of birth defects in Dongguan City during 2013-2017.

Methods: The data were from preconception examinations system and the birth defects surveillance system during 2013-2017. The study population included 63 175 infants born to mothers accepted preconception examinations during pregnancy (the screening group) and 649 862 infants whose mother did not check (the control group). Read More

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December 2018

REVIEWS OF ACOUSTICAL PATENTS.

J Acoust Soc Am 2018 Nov;144(5):2645

11222 Flatiron Drive, Lafayette, Colorado 80026.

. Read More

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November 2018

[The Influence of Residence Status on Psychiatric Symptom Load of Asylum Seekers in Germany].

Psychiatr Prax 2018 Dec 12. Epub 2018 Dec 12.

Psychiatrische Universitätsklinik der Charité im St. Hedwig-Krankenhaus Berlin.

Background: The aim of this study was to assess asylum seekers' views on their legal situations, asylum procedures and living conditions, and the relationship of these factors towards psychological stress.

Methods: 650 asylum seekers in Berlin received a questionnaire.

Results: 76,3 % (N = 496) completed the questionnaires in full. Read More

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December 2018
2 Reads

Safety Considerations When Working with Humanized Animals.

ILAR J 2018 Dec 12. Epub 2018 Dec 12.

Unit for Laboratory Animal Medicine, University of Michigan Medical School in Ann Arbor, Michigan.

Research using laboratory animals has been revolutionized by the creation of humanized animal models, which are immunodeficient animals engrafted with human cells, tissues, or organs. These animal models provide the research community a unique and promising opportunity to mimic a wide variety of disease conditions in humans, from infectious disease to cancer. A vast majority of these models are humanized mice like those injected with human CD34+ hematopoietic stem cells and patient-derived xenografts. Read More

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December 2018

A scoping review of Advanced Practice Registered Nurses Consensus Model outcomes: Part four of a four-part series on critical topics identified by the 2015 Nurse Practitioner Research Agenda.

J Am Assoc Nurse Pract 2018 Dec;30(12):710-723

School of Pharmacy, University of Utah, Salt Lake City, Utah.

Background And Purpose: The Advanced Practice Registered Nurses (APRN) Consensus Model was produced by the APRN Joint Dialogue Group in 2008. The aim of the Consensus Model is to guide state boards on the implementation of APRN practice components, including licensure, accreditation, certification, and education and to clarify the legal scope of practice and APRN roles. The purpose of this scoping review and gap analysis was to appraise the evidence related to patient, nurse practitioner (NP) and organizational outcomes resulting from the Consensus Model. Read More

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December 2018

Cultivating inclusivity in precision medicine research: disability, diversity, and cultural competence.

Authors:
Maya Sabatello

J Community Genet 2018 Dec 12. Epub 2018 Dec 12.

Center for Research on Ethical, Legal & Social Implications of Psychiatric, Neurologic & Behavioral Genetics, Columbia University, New York, NY, USA.

Cultural competence is increasingly viewed as key for the inclusion of diverse populations in precision medicine research (PMR) in the USA. Precision medicine researchers and personnel are thus increasingly expected to undergo cultural competency trainings and to engage with relevant racial/ethnic communities to ensure that all research components are culturally and linguistically sensitive to these communities. However, the need for PMR enterprises to ensure competence with and understanding of disability rights, history, and needs (hereinafter disability culture competency) have not received attention. Read More

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December 2018

Letter to the Editor: An Autism Parent's Response to Papatola and Lustig's Paper on Navigating a Managed Care Peer Review in .

Authors:
Cathy Beier

Behav Anal Pract 2018 Dec 5;11(4):517-518. Epub 2018 Jun 5.

Beier Family, Lafayette, CA USA.

An autism parent disputes the authors' premise that the role of the BCBA is to "transition treatment to parents." Parents cannot simply "take over" all the advanced degrees, thousands of hours of coursework practicum and exams, or depth and breadth of scientific knowledge required to earn a BCBA any more than we can (or should) "take over" our kids' pediatric care or prescribe their meds. Papatola and Lustig's employer, Cigna Behavioral Health, recently made "transition treatment to parents" a criterion of medical necessity for ABA. Read More

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December 2018

The Mediating Effects of Derived Relational Responding on the Relationship Between Verbal Operant Development and IQ.

Behav Anal Pract 2018 Dec 31;11(4):411-416. Epub 2018 May 31.

Rehabilitation Institute, Southern Illinois University, Carbondale, IL 62901 USA.

Dixon, Belisle, and Stanley, (2018) demonstrated a strong, significant relationship between derived relational responding and intelligence in individuals with autism. We extended these results by evaluating the degree to which participant results on the PEAK Equivalence Pre-assessment (PEAK-E-PA, a direct assessment of derived relational responding) mediated the relationship between the PEAK Direct Training Assessment (PEAK-DT-A, a Skinnerian-based assessment of verbal development) and intelligence. Results support strong, positive correlations between both assessments (PEAK-DT-A and PEAK-E-PA) and IQ; however, the relationship between PEAK-DT-A and IQ could be explained in terms of participant results on the PEAK-E-PA alone. Read More

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December 2018

Promoting Generalized Advanced Language Skills of Children in Intensive Behavioral Intervention with Promoting the Emergence of Advanced Knowledge Generalization Module (PEAK-G).

Behav Anal Pract 2018 Dec 26;11(4):289-306. Epub 2018 Jan 26.

3Rehabilitation Institute, Southern Illinois University, Carbondale, IL USA.

The Promoting the Emergence of Advanced Knowledge Relational Training System Generalization Module (PEAK-G; Dixon, 2014) was used within a community-based intensive behavioral intervention (IBI) program to enhance the generalized advanced language skills of children diagnosed with autism spectrum disorder. Four multiple-baseline, across-behaviors designs were used to assess the effectiveness of the PEAK-G "train and test" discrete trial training (DTT) method on directly trained and generalized language skills. After implementing PEAK-G, directly trained language skills increased for all participants, and generalization to test stimuli was observed for two participants, with some generalization observed for a third participant. Read More

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December 2018

Biobanks in Horizon 2020: sustainability and attractive perspectives.

EPMA J 2018 Dec 23;9(4):345-353. Epub 2018 Nov 23.

Department of Immunochemistry, University Hospital Pilsen, Edvarda Benese 1128/13, 305 99 Pilsen, CZ Czech Republic.

Biobanks have during last two decades gained an important role in the whole process of biomedical research and health care not only in Europe but also worldwide. Biobanks are one of the pillars in personalised medicine tackling all its aspects such as prevention, diagnosis, treatment and monitoring closely the specific characteristics of an individual patient. The current and future power of biobanks is the amount of samples of high-quality and related information available for current and future research of diseases, for optimising patients´ prevention, diagnosis, treatment and monitoring. Read More

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December 2018
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Current challenges in health information technology-related patient safety.

Health Informatics J 2018 Dec 11:1460458218814893. Epub 2018 Dec 11.

Center for Innovations in Quality, Effectiveness and Safety, Michael E DeBakey Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas, USA.

We identify and describe nine key, short-term, challenges to help healthcare organizations, health information technology developers, researchers, policymakers, and funders focus their efforts on health information technology-related patient safety. Categorized according to the stage of the health information technology lifecycle where they appear, these challenges relate to (1) developing models, methods, and tools to enable risk assessment; (2) developing standard user interface design features and functions; (3) ensuring the safety of software in an interfaced, network-enabled clinical environment; (4) implementing a method for unambiguous patient identification (1-4 Design and Development stage); (5) developing and implementing decision support which improves safety; (6) identifying practices to safely manage information technology system transitions (5 and 6 Implementation and Use stage); (7) developing real-time methods to enable automated surveillance and monitoring of system performance and safety; (8) establishing the cultural and legal framework/safe harbor to allow sharing information about hazards and adverse events; and (9) developing models and methods for consumers/patients to improve health information technology safety (7-9 Monitoring, Evaluation, and Optimization stage). These challenges represent key "to-do's" that must be completed before we can expect to have safe, reliable, and efficient health information technology-based systems required to care for patients. Read More

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December 2018
0.787 Impact Factor