357 results match your criteria Lead Poisoning Imaging

Development of delayed neurologic sequelae in acute carbon monoxide poisoning cases caused by briquette-based kotatsu: A case-control study.

Medicine (Baltimore) 2021 Apr;100(16):e25009

Department of Emergency and Critical Care Medicine, Fukushima Medical University, Fukushima City, Fukushima, Japan.

Abstract: Briquette-based kotatsu, a traditional Japanese heating system, is still used in rural areas and has been linked to the development of acute carbon monoxide (CO) poisoning. This study aimed to investigate the occurrence of delayed neurologic sequelae (DNS) in patients with acute CO poisoning caused by briquette-based kotatsu.This retrospective study included 17 patients treated for acute CO poisoning due to briquette-based kotatsu, between April 2017 and March 2020. Read More

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Analysis of lead distribution in avian organs by LA-ICP-MS: Study of experimentally lead-exposed ducks and kites.

Environ Pollut 2021 Aug 5;283:117086. Epub 2021 Apr 5.

Laboratory of Toxicology, Faculty of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo, Hokkaido, 060-0818, Japan.

Lead poisoning of wild birds by ingestion of lead ammunition occurs worldwide. Histopathological changes in organs of lead-intoxicated birds are widely known, and lead concentration of each organ is measurable using mass spectrometry. However, detailed lead localization at the suborgan level has remained elusive in lead-exposed birds. Read More

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Near-infrared light excited UCNP-DNAzyme nanosensor for selective detection of Pb and in vivo imaging.

Talanta 2021 May 29;227:122156. Epub 2021 Jan 29.

Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha, 410081, PR China. Electronic address:

Due to similar charges, atomic radii, and chemical properties of most metal ions, the selective sensing of these metal ions and imaging in vivo is still a challenge. A DNAzyme assemblied and near-infrared (NIR) light excited nanosensor was developed to detect and image Pb. In this nanosensor, NaYF:Yb, Er upconversion nanoparticles (UCNPs) introduced as NIR-to-Vis transducer were the donor of luminescence resonance energy transfer (LRET), and DNAzyme-functionalized black hole quencher 1 (BHQ1) acted as energy transfer acceptor. Read More

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Convulsive status epilepticus as the initial presentation of superwarfarin poisoning: a case report.

Ann Palliat Med 2020 Oct 22. Epub 2020 Oct 22.

Department of Neurology, First Hospital of Jilin University, Changchun, China; Department of Life Sciences, National Natural Science Foundation of China, Beijing, China.

Bromadiolone, a widely-used rodent control drug, could act as a long-acting anticoagulant. Patients of bromadiolone poisoning often present with multiorgan hemorrhage. However, neurological symptoms of bromadiolone poisoning are seldom reported. Read More

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October 2020

Mothball ingestion as a manifestation of pica, leading to paradichlorobenzene CNS toxicity.

Afr Health Sci 2020 Jun;20(2):932-935

Department of Neurology, Albert Einstein Medical Center, Philadelphia PA, USA.

Background: Pica is a poorly understood psychiatric disorder that presents with the ingestion of non-nutritious substances for unclear reasons. A high index of suspicion for unusual toxin exposure aids in the diagnosis of pica patients presenting with unexplained neurodegenerative features.

Methods: We present a 47-year-old female with worsening gait over the past year. Read More

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Severe neurological nicotine intoxication by e-cigarette liquids: Systematic literature review.

Acta Neurol Scand 2021 Feb 20;143(2):121-130. Epub 2020 Sep 20.

Neurophysiopathology Unit, Neuromuscolar Department, AOU Careggi, Florence, Italy.

Electronic cigarettes are a popular, easily purchased, alternative source of nicotine that is considered safer than conventional tobacco. However, Intentional or accidental exposure to e-liquid substances, mainly nicotine, can lead to serious, potentially fatal toxicity. Emergency and critical care physicians should keep in mind acute intoxication of this poison with a biphasic toxic syndrome. Read More

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February 2021

Colchicine poisoning complicated by medulla oblongata myelinolysis: a case report.

Ann Palliat Med 2021 Feb 25;10(2):2349-2353. Epub 2020 May 25.

Department of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun, China.

Medulla oblongata myelinolysis is an extremely rare manifestation of extrapontine myelinolysis (EPM). Herein, we report a case of a 34-year-old man with a history of gout who presented repeated vomiting and diarrhea after ingesting 15 colchicine pills. A hyponatremia diagnosis was given and after an intensive treatment, his serum sodium level increased from 118 to 129 mmol/L within 24 hours. Read More

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February 2021

Acute Disulfiram Poisoning in a Child: A Case Report and Review of Literature.

Indian J Crit Care Med 2020 Mar;24(3):203-205

Department of Pharmacology, Pandit Bhagwat Dayal Sharma Postgraduate Institute of Medical Sciences, Rohtak, Haryana, India.

Aim: To determine the significance of acute disulfiram poisoning in pediatric population.

Background: Disulfiram poisoning in children is uncommon, can occur in children who have ingested large amount of drug because of careless and unsafe storage. Only few cases have been reported in literature. Read More

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Diagnostic utility of arterial spin labeling in identifying changes in brain perfusion in patients with carbon monoxide poisoning.

Clin Imaging 2020 Aug 11;64:92-96. Epub 2020 Apr 11.

Department of Emergency Medicine, University of Health Sciences, Konya Training and Research Hospital, Konya, Turkey.

Objective: Carbon monoxide (CO) poisoning is one of the most common poisonings worldwide. The affinity of hemoglobin for CO is significantly higher than that for oxygen, and the formation of carboxy-hemoglobin leads to a decrease in the capacity of blood to transport oxygen to tissues, tissue hypoxia, and early perfusion changes in the affected tissue. This study aimed to investigate the utility of arterial spin labeling perfusion imaging (ASL-PI) in revealing cerebral vascular hemodynamic changes in patients presenting to the emergency room with CO poisoning and to compare findings with those from diffusion-weighted imaging (DWI). Read More

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Encephalopathy following ingestion of Lead-contaminated opium; magnetic resonance imaging findings.

BMC Neurol 2020 May 1;20(1):166. Epub 2020 May 1.

Department of Neurology, Loghman-Hakim Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: Encephalopathy is an uncommon but serious presentation of lead toxicity.

Objective: We aimed to determine and follow-up the brain magnetic resonance imaging (MRI) abnormalities in the patients with lead encephalopathy due to ingestion of lead contaminated opium.

Methods: In a cross-sectional study during lead-contaminated opium outbreak, all lead-poisoned patients with any signs/symptoms of encephalopathy were included. Read More

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Pseudotumor Caused by a Retained Intra-articular Bullet: A Case Report.

JBJS Case Connect 2020 Jan-Mar;10(1):e0209

Department of Orthopaedic Surgery, University of California San Francisco-Fresno, Fresno, California.

Case: A 54-year-old man presented with systemic lead poisoning due to a gunshot wound to the hip suffered 35 years prior to presentation. He urgently underwent removal of the bullet with total hip arthroplasty and was found to have a pseudotumor. This case highlights the team-based approach to manage systemic lead poisoning caused by an intra-articular bullet. Read More

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January 2021

Imaging methods used in the assessment of environmental disease networks: a brief review for clinicians.

Insights Imaging 2020 Feb 7;11(1):18. Epub 2020 Feb 7.

Directorate of Research, Hospital General de Mexico "Dr. Eduardo Liceaga", Mexico City, Mexico.

Background: Across the globe, diseases secondary to environmental exposures have been described, and it was also found that existing diseases have been modified by exposure to environmental chemicals or an environmental factor that has been found in their pathogenesis. The Institute of Medicine has shared a permanent concern related to the nations environmental health capacity since 1988.

Main Body: Contemporary imaging methods in the last 15 years started reporting alterations in different human systems such as the central nervous system, cardiovascular system and pulmonary system among others; evidence suggests the existence of a human environmental disease network. Read More

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February 2020

Transient ST Segment Elevation Caused by Intracoronary Thrombus after Acute Carbon Monoxide Poisoning.

Prehosp Disaster Med 2019 Dec 9;34(6):677-680. Epub 2019 Oct 9.

Eskisehir State Hospital, Department of Cardiology, Eskişehir, Turkey.

Carbon monoxide (CO) poisoning is the most common cause of death and injury among all poisonings. Myocardial injury is detected in one-third of CO poisonings. In this Case Report, a previously healthy 41-year-old man was referred for CO poisoning. Read More

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December 2019

The Design and Application of an Appropriate Parkinson's Disease Animal Model in Regenerative Medicine.

Adv Exp Med Biol 2019 Sep 5. Epub 2019 Sep 5.

Cell Therapy and Regenerative Medicine Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.

Objectives: Aging as an inevitable and complex physiological process occurs through a progressive decrease in the potential of tissue regeneration. Given the increasing global outbreak of aging and age-related disorders, it is important to control this phenomenon. Parkinson's disease (one of the age-related neurodegenerative and progressive disorders) resulted from predominant dopaminergic neurons deficiency. Read More

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September 2019

Management of Ingested Lead Pellets With Elevated Blood Lead Levels in a Pediatric Patient.

J Pediatr Gastroenterol Nutr 2019 12;69(6):e159-e160

Division of Pediatric Surgery, Department of Surgery, Virginia Commonwealth University, Richmond, VA.

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December 2019

Lead poisoning due to ingestion of lead-contaminated opium: A diagnostic study on patients' imaging findings.

J Trace Elem Med Biol 2019 Sep 25;55:26-32. Epub 2019 Apr 25.

Washington Poison Center, Seattle, WA, USA.

Objectives: Our study attempts to determine if for patients following ingestion of lead-contaminated opium, radiographs [plain X-ray (KUB)] or unenhanced computed tomography (CT scan) of the abdomen may be predictive of lead poisoning.

Methods: Our study is concerned with patients of >21 years with elevated lead concentrations, who had undergone KUB or CT. Patients with other toxicities who had undergone similar imaging profiles but who had low blood lead level (BLL) were enrolled as controls. Read More

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September 2019

Clinical analysis of severe visual loss caused by inhalational methanol poisoning in a chronic process with acute onset:a retrospective clinical analysis.

BMC Ophthalmol 2019 Jun 7;19(1):124. Epub 2019 Jun 7.

Department of Neurology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China.

Background: To analyze the clinical features and prognosis of the visual loss resulted from inhalational methanol poisoning in 8 Chinese patients.

Methods: Eight consecutive patients seen at the Beijing Tongren Hospital of Capital Medical University, Beijing, China between January 2003 to August 2017, with complains of vision loss in both eyes, identified as inhalational methanol poisoning. Detailed medical history was extracted. Read More

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Metal Ion-Chelated Tannic Acid Coating for Hemostatic Dressing.

Materials (Basel) 2019 Jun 3;12(11). Epub 2019 Jun 3.

Liaoning Key Laboratory of Molecular Recognition and Imaging, School of Bioengineering, Dalian University of Technology, Dalian 116023, China.

Tannic acid (TA), a high-molecular-weight polyphenol, is used as a hemostasis spray and unguent for trauma wound remedy in traditional medical treatment. However, the use of tannic acid on a large-area wound would lead to absorption poisoning. In this work, a TA coating was assembled on a quartz/silicon slide, or medical gauze, via chelation interaction between TA and Fe ions and for further use as a hemostasis dressing. Read More

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Variant angina induced by carbon monoxide poisoning: A CARE compliant case report.

Medicine (Baltimore) 2019 Apr;98(16):e15056

Department of Emergency.

Rationale: Carbon monoxide (CO) poisoning can cause severe damage to the nervous system, and can also cause serious damage to organs, such as the heart, kidneys, and lungs. CO damage to myocardial cells has been previously reported. This can lead to serious complications, such as myocardial infarction. Read More

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Corrosive injuries of the upper gastrointestinal tract: A pictorial review of the imaging features.

Indian J Radiol Imaging 2019 Jan-Mar;29(1):6-13

Department of Gastroenterology, Postgraduate Institute of Medical Imaging and Research (PGIMER), Chandigarh, India.

Corrosive ingestion is a common form of poisoning. Corrosive agents cause severe damage to the gastrointestinal (GI) tract. The most severe forms of injury can lead to mortality; however, the major concern with this type of injury is life-long morbidity. Read More

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Prenatal lead exposure impacts cross-hemispheric and long-range connectivity in the human fetal brain.

Neuroimage 2019 05 7;191:186-192. Epub 2019 Feb 7.

Department of Psychology, Michigan State University, East Lansing, MI, USA.

Lead represents a highly prevalent metal toxicant with potential to alter human biology in lasting ways. A population segment that is particularly vulnerable to the negative consequences of lead exposure is the human fetus, as exposure events occurring before birth are linked to varied and long-ranging negative health and behavioral outcomes. An area that has yet to be addressed is the potential that lead exposure during pregnancy alters brain development even before an individual is born. Read More

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[Lead intoxication revealing sickle cell disease].

Pan Afr Med J 2018 31;30:305. Epub 2018 Aug 31.

Service de Rhumatologie, CHU Mohammed VI, BP 2360 principal, Avenue Ibn Sina, Marrakech, Maroc.

We here report the case of a 18 year old patient with two brothers who died from sickle cell anemia. He had a 5-day history of diffuse bone pain. He had drunk a preparation containing lead to obtain an analgesic effect without improvement. Read More

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January 2019

Lead Toxicity from a Retained Bullet.

N Engl J Med 2018 Dec;379(25):2451

John H. Stroger Hospital of Cook County, Chicago, IL

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December 2018

Gastrointestinal: An oral clue to an unusual cause of pain abdomen: Burton's line.

J Gastroenterol Hepatol 2019 Apr 18;34(4):629. Epub 2018 Nov 18.

Department of Gastroenterology, Internal medicine and GI Radiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

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Oxidative stress in the neurodegenerative brain following lifetime exposure to lead in rats: Changes in lifespan profiles.

Toxicology 2019 01 13;411:101-109. Epub 2018 Nov 13.

Department of Occupational Health and Toxicology, School of Public Health, Nanchang University, Nanchang, 330006, China; Jiangxi Provincial Key Laboratory of Preventive Medicine, Nanchang University, Nanchang, 330006, China. Electronic address:

A large number of studies have evidenced that developmental neurotoxicity induced by lead (Pb) is related to oxidative injury. Furthermore, recent studies have found that developmental Pb exposure can induce neurodegeneration in old age. Because of the common presence of Pb in the environment, humans are exposed to this metal throughout their lifetime. Read More

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January 2019

Characterization and imaging of lead distribution in bones of lead-exposed birds by ICP-MS and LA-ICP-MS.

Chemosphere 2018 Dec 31;212:994-1001. Epub 2018 Aug 31.

Laboratory of Toxicology, Department of Environmental Veterinary Sciences, School of Veterinary Medicine, Hokkaido University, Sapporo, Kita18, Nishi9, Kita-ku, Sapporo, Hokkaido 060-0818, Japan. Electronic address:

Lead (Pb) poisoning in raptors and water birds is a serious problem in many countries. However, only a small fraction of Pb poisoning has been detected in birds. Bone specimens may be useful indices of Pb exposure because bones contain ∼90% of the total Pb body burden. Read More

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December 2018

Franklin expedition lead exposure: New insights from high resolution confocal x-ray fluorescence imaging of skeletal microstructure.

PLoS One 2018 23;13(8):e0202983. Epub 2018 Aug 23.

Department of Anatomy, Physiology and Pharmacology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.

In the summer of 1845, under the command of Sir John Franklin, 128 officers and men aboard Royal Navy ships HMS Erebus and HMS Terror sailed into Lancaster Sound and entered the waters of Arctic North America. The goal of this expedition was to complete the discovery of a northwest passage by navigating the uncharted area between Barrow Strait and Simpson Strait. Franklin and his crew spent the first winter at Beechey Island, where three crewmen died and were buried. Read More

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February 2019

Lead Pellet Ingestion in 3 Children: Another Source for Lead Toxicity.

Pediatr Emerg Care 2019 May;35(5):385-388

Acute ingestions of spherical lead ammunition foreign bodies such as bullets and lead shot can cause acute blood lead level elevations and clinical symptoms necessitating emergency department evaluations and sometimes treatment. This article presents 3 cases of children ingesting lead ammunition, all receiving gastrointestinal (GI) decontamination and chelation therapy for significantly elevated blood lead level. Case-specific exposures and treatments for the lead ammunitions are presented. Read More

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Pellets in the Eye: Cerebral Aneurysm and Encephalomyeloneuropathy as Presenting Syndromes.

J Stroke Cerebrovasc Dis 2018 Dec 3;27(12):3670-3672. Epub 2018 Aug 3.

Department of Neurology, Sanjay Gandhi Post Graduate Medical Sciences. Electronic address:

Lead poisoning following retained gunshot pellets resulting in recurrent episodes of encephalomyeloneuropathy is rare and association of intracranial aneurysm with lead poisoning is interesting. The case report describes about a 58-year ayurvedic doctor who was hospitalized for recurrent abdominal pain and limb weakness appearing spontaneously and improving in a few days to weeks. He had 20 such attacks in last 30 years starting at 25 years after the gunshot wound that resulted in retention of 2 lead pellets in his skull. Read More

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December 2018