348 results match your criteria Lead Poisoning Imaging


Colchicine poisoning complicated by medulla oblongata myelinolysis: a case report.

Ann Palliat Med 2020 May 25. Epub 2020 May 25.

Department of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun, China.

Medulla oblongata myelinolysis is an extremely rare manifestation of extrapontine myelinolysis (EPM). Herein, we report a case of a 34-year-old man with a history of gout who presented repeated vomiting and diarrhea after ingesting 15 colchicine pills. A hyponatremia diagnosis was given and after an intensive treatment, his serum sodium level increased from 118 to 129 mmol/L within 24 hours. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm-19-627DOI Listing

Acute Disulfiram Poisoning in a Child: A Case Report and Review of Literature.

Indian J Crit Care Med 2020 Mar;24(3):203-205

Department of Pharmacology, Pandit Bhagwat Dayal Sharma Postgraduate Institute of Medical Sciences, Rohtak, Haryana, India.

Aim: To determine the significance of acute disulfiram poisoning in pediatric population.

Background: Disulfiram poisoning in children is uncommon, can occur in children who have ingested large amount of drug because of careless and unsafe storage. Only few cases have been reported in literature. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5005/jp-journals-10071-23371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225768PMC

Diagnostic utility of arterial spin labeling in identifying changes in brain perfusion in patients with carbon monoxide poisoning.

Clin Imaging 2020 Aug 11;64:92-96. Epub 2020 Apr 11.

Department of Emergency Medicine, University of Health Sciences, Konya Training and Research Hospital, Konya, Turkey.

Objective: Carbon monoxide (CO) poisoning is one of the most common poisonings worldwide. The affinity of hemoglobin for CO is significantly higher than that for oxygen, and the formation of carboxy-hemoglobin leads to a decrease in the capacity of blood to transport oxygen to tissues, tissue hypoxia, and early perfusion changes in the affected tissue. This study aimed to investigate the utility of arterial spin labeling perfusion imaging (ASL-PI) in revealing cerebral vascular hemodynamic changes in patients presenting to the emergency room with CO poisoning and to compare findings with those from diffusion-weighted imaging (DWI). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clinimag.2020.04.006DOI Listing

Imaging methods used in the assessment of environmental disease networks: a brief review for clinicians.

Insights Imaging 2020 Feb 7;11(1):18. Epub 2020 Feb 7.

Directorate of Research, Hospital General de Mexico "Dr. Eduardo Liceaga", Mexico City, Mexico.

Background: Across the globe, diseases secondary to environmental exposures have been described, and it was also found that existing diseases have been modified by exposure to environmental chemicals or an environmental factor that has been found in their pathogenesis. The Institute of Medicine has shared a permanent concern related to the nations environmental health capacity since 1988.

Main Body: Contemporary imaging methods in the last 15 years started reporting alterations in different human systems such as the central nervous system, cardiovascular system and pulmonary system among others; evidence suggests the existence of a human environmental disease network. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13244-019-0814-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007482PMC
February 2020

Transient ST Segment Elevation Caused by Intracoronary Thrombus after Acute Carbon Monoxide Poisoning.

Prehosp Disaster Med 2019 Dec 9;34(6):677-680. Epub 2019 Oct 9.

Eskisehir State Hospital, Department of Cardiology, Eskişehir, Turkey.

Carbon monoxide (CO) poisoning is the most common cause of death and injury among all poisonings. Myocardial injury is detected in one-third of CO poisonings. In this Case Report, a previously healthy 41-year-old man was referred for CO poisoning. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S1049023X19004898DOI Listing
December 2019

The Design and Application of an Appropriate Parkinson's Disease Animal Model in Regenerative Medicine.

Adv Exp Med Biol 2019 Sep 5. Epub 2019 Sep 5.

Cell Therapy and Regenerative Medicine Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.

Objectives: Aging as an inevitable and complex physiological process occurs through a progressive decrease in the potential of tissue regeneration. Given the increasing global outbreak of aging and age-related disorders, it is important to control this phenomenon. Parkinson's disease (one of the age-related neurodegenerative and progressive disorders) resulted from predominant dopaminergic neurons deficiency. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/5584_2019_422DOI Listing
September 2019
4 Reads

Lead poisoning due to ingestion of lead-contaminated opium: A diagnostic study on patients' imaging findings.

J Trace Elem Med Biol 2019 Sep 25;55:26-32. Epub 2019 Apr 25.

Washington Poison Center, Seattle, WA, USA.

Objectives: Our study attempts to determine if for patients following ingestion of lead-contaminated opium, radiographs [plain X-ray (KUB)] or unenhanced computed tomography (CT scan) of the abdomen may be predictive of lead poisoning.

Methods: Our study is concerned with patients of >21 years with elevated lead concentrations, who had undergone KUB or CT. Patients with other toxicities who had undergone similar imaging profiles but who had low blood lead level (BLL) were enrolled as controls. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtemb.2019.04.016DOI Listing
September 2019

Clinical analysis of severe visual loss caused by inhalational methanol poisoning in a chronic process with acute onset:a retrospective clinical analysis.

BMC Ophthalmol 2019 Jun 7;19(1):124. Epub 2019 Jun 7.

Department of Neurology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China.

Background: To analyze the clinical features and prognosis of the visual loss resulted from inhalational methanol poisoning in 8 Chinese patients.

Methods: Eight consecutive patients seen at the Beijing Tongren Hospital of Capital Medical University, Beijing, China between January 2003 to August 2017, with complains of vision loss in both eyes, identified as inhalational methanol poisoning. Detailed medical history was extracted. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12886-019-1127-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554876PMC
June 2019
8 Reads

Metal Ion-Chelated Tannic Acid Coating for Hemostatic Dressing.

Materials (Basel) 2019 Jun 3;12(11). Epub 2019 Jun 3.

Liaoning Key Laboratory of Molecular Recognition and Imaging, School of Bioengineering, Dalian University of Technology, Dalian 116023, China.

Tannic acid (TA), a high-molecular-weight polyphenol, is used as a hemostasis spray and unguent for trauma wound remedy in traditional medical treatment. However, the use of tannic acid on a large-area wound would lead to absorption poisoning. In this work, a TA coating was assembled on a quartz/silicon slide, or medical gauze, via chelation interaction between TA and Fe ions and for further use as a hemostasis dressing. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ma12111803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600752PMC
June 2019
3 Reads

Variant angina induced by carbon monoxide poisoning: A CARE compliant case report.

Medicine (Baltimore) 2019 Apr;98(16):e15056

Department of Emergency.

Rationale: Carbon monoxide (CO) poisoning can cause severe damage to the nervous system, and can also cause serious damage to organs, such as the heart, kidneys, and lungs. CO damage to myocardial cells has been previously reported. This can lead to serious complications, such as myocardial infarction. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000015056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494374PMC
April 2019
17 Reads

Corrosive injuries of the upper gastrointestinal tract: A pictorial review of the imaging features.

Indian J Radiol Imaging 2019 Jan-Mar;29(1):6-13

Department of Gastroenterology, Postgraduate Institute of Medical Imaging and Research (PGIMER), Chandigarh, India.

Corrosive ingestion is a common form of poisoning. Corrosive agents cause severe damage to the gastrointestinal (GI) tract. The most severe forms of injury can lead to mortality; however, the major concern with this type of injury is life-long morbidity. Read More

View Article

Download full-text PDF

Source
http://www.ijri.org/text.asp?2019/29/1/6/255229
Publisher Site
http://dx.doi.org/10.4103/ijri.IJRI_349_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467036PMC
April 2019
16 Reads

Prenatal lead exposure impacts cross-hemispheric and long-range connectivity in the human fetal brain.

Neuroimage 2019 05 7;191:186-192. Epub 2019 Feb 7.

Department of Psychology, Michigan State University, East Lansing, MI, USA.

Lead represents a highly prevalent metal toxicant with potential to alter human biology in lasting ways. A population segment that is particularly vulnerable to the negative consequences of lead exposure is the human fetus, as exposure events occurring before birth are linked to varied and long-ranging negative health and behavioral outcomes. An area that has yet to be addressed is the potential that lead exposure during pregnancy alters brain development even before an individual is born. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10538119193010
Publisher Site
http://dx.doi.org/10.1016/j.neuroimage.2019.02.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451829PMC
May 2019
8 Reads

[Lead intoxication revealing sickle cell disease].

Pan Afr Med J 2018 31;30:305. Epub 2018 Aug 31.

Service de Rhumatologie, CHU Mohammed VI, BP 2360 principal, Avenue Ibn Sina, Marrakech, Maroc.

We here report the case of a 18 year old patient with two brothers who died from sickle cell anemia. He had a 5-day history of diffuse bone pain. He had drunk a preparation containing lead to obtain an analgesic effect without improvement. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.11604/pamj.2018.30.305.16222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320453PMC
January 2019
6 Reads

Lead Toxicity from a Retained Bullet.

N Engl J Med 2018 Dec;379(25):2451

John H. Stroger Hospital of Cook County, Chicago, IL

View Article

Download full-text PDF

Source
http://www.nejm.org/doi/10.1056/NEJMicm1804726
Publisher Site
http://dx.doi.org/10.1056/NEJMicm1804726DOI Listing
December 2018
26 Reads

Gastrointestinal: An oral clue to an unusual cause of pain abdomen: Burton's line.

J Gastroenterol Hepatol 2019 Apr 18;34(4):629. Epub 2018 Nov 18.

Department of Gastroenterology, Internal medicine and GI Radiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jgh.14519DOI Listing
April 2019
20 Reads

Oxidative stress in the neurodegenerative brain following lifetime exposure to lead in rats: Changes in lifespan profiles.

Toxicology 2019 01 13;411:101-109. Epub 2018 Nov 13.

Department of Occupational Health and Toxicology, School of Public Health, Nanchang University, Nanchang, 330006, China; Jiangxi Provincial Key Laboratory of Preventive Medicine, Nanchang University, Nanchang, 330006, China. Electronic address:

A large number of studies have evidenced that developmental neurotoxicity induced by lead (Pb) is related to oxidative injury. Furthermore, recent studies have found that developmental Pb exposure can induce neurodegeneration in old age. Because of the common presence of Pb in the environment, humans are exposed to this metal throughout their lifetime. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S0300483X183025
Publisher Site
http://dx.doi.org/10.1016/j.tox.2018.11.003DOI Listing
January 2019
39 Reads

Characterization and imaging of lead distribution in bones of lead-exposed birds by ICP-MS and LA-ICP-MS.

Chemosphere 2018 Dec 31;212:994-1001. Epub 2018 Aug 31.

Laboratory of Toxicology, Department of Environmental Veterinary Sciences, School of Veterinary Medicine, Hokkaido University, Sapporo, Kita18, Nishi9, Kita-ku, Sapporo, Hokkaido 060-0818, Japan. Electronic address:

Lead (Pb) poisoning in raptors and water birds is a serious problem in many countries. However, only a small fraction of Pb poisoning has been detected in birds. Bone specimens may be useful indices of Pb exposure because bones contain ∼90% of the total Pb body burden. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00456535183163
Publisher Site
http://dx.doi.org/10.1016/j.chemosphere.2018.08.149DOI Listing
December 2018
44 Reads

Franklin expedition lead exposure: New insights from high resolution confocal x-ray fluorescence imaging of skeletal microstructure.

PLoS One 2018 23;13(8):e0202983. Epub 2018 Aug 23.

Department of Anatomy, Physiology and Pharmacology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.

In the summer of 1845, under the command of Sir John Franklin, 128 officers and men aboard Royal Navy ships HMS Erebus and HMS Terror sailed into Lancaster Sound and entered the waters of Arctic North America. The goal of this expedition was to complete the discovery of a northwest passage by navigating the uncharted area between Barrow Strait and Simpson Strait. Franklin and his crew spent the first winter at Beechey Island, where three crewmen died and were buried. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0202983PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107236PMC
February 2019
31 Reads

Lead Pellet Ingestion in 3 Children: Another Source for Lead Toxicity.

Pediatr Emerg Care 2019 May;35(5):385-388

Acute ingestions of spherical lead ammunition foreign bodies such as bullets and lead shot can cause acute blood lead level elevations and clinical symptoms necessitating emergency department evaluations and sometimes treatment. This article presents 3 cases of children ingesting lead ammunition, all receiving gastrointestinal (GI) decontamination and chelation therapy for significantly elevated blood lead level. Case-specific exposures and treatments for the lead ammunitions are presented. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PEC.0000000000001469DOI Listing
May 2019
11 Reads

Pellets in the Eye: Cerebral Aneurysm and Encephalomyeloneuropathy as Presenting Syndromes.

J Stroke Cerebrovasc Dis 2018 Dec 3;27(12):3670-3672. Epub 2018 Aug 3.

Department of Neurology, Sanjay Gandhi Post Graduate Medical Sciences. Electronic address:

Lead poisoning following retained gunshot pellets resulting in recurrent episodes of encephalomyeloneuropathy is rare and association of intracranial aneurysm with lead poisoning is interesting. The case report describes about a 58-year ayurvedic doctor who was hospitalized for recurrent abdominal pain and limb weakness appearing spontaneously and improving in a few days to weeks. He had 20 such attacks in last 30 years starting at 25 years after the gunshot wound that resulted in retention of 2 lead pellets in his skull. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2018.07.018DOI Listing
December 2018
6 Reads

Evaluation Selenocysteine Protective Effect in Carbon Disulfide Induced Hepatitis with a Mitochondrial Targeting Ratiometric Near-Infrared Fluorescent Probe.

Anal Chem 2018 07 12;90(13):8108-8115. Epub 2018 Jun 12.

CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Research Centre for Coastal Environmental Engineering and Technology, Yantai Institute of Coastal Zone Research , Chinese Academy of Sciences , Yantai 264003 , China.

As important active sites of oxidoreductase in mitochondria, selenocysteine (Sec) takes the responsibility for cytoprotective effect and intracellular redox homeostasis. Carbon disulfide (CS) is a common solvent in industry, which can inhibit the activities of oxidoreductase and induce oxidative stress. It is necessary to investigate the cytoprotective effect of Sec against CS exposure. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.analchem.8b01306DOI Listing
July 2018
34 Reads

Progressive Chronic Retinal Axonal Loss Following Acute Methanol-induced Optic Neuropathy: Four-Year Prospective Cohort Study.

Am J Ophthalmol 2018 07 28;191:100-115. Epub 2018 Apr 28.

Toxicological Information Centre, Department of Occupational Medicine, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic. Electronic address:

Purpose: To study the dynamics and clinical determinants of chronic retinal nerve fiber layer thickness (RNFL) loss after methanol-induced optic neuropathy.

Design: Prospective cohort study.

Methods: All patients underwent complete ophthalmic evaluation including spectral-domain optical coherence tomography 3 times during 4 years of observation: 4. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.04.015DOI Listing
July 2018
25 Reads

The Use of Lead Isotope Analysis to Identify Potential Sources of Lead Toxicosis in a Juvenile Bald Eagle ( Haliaeetus leucocephalus) With Ventricular Foreign Bodies.

J Avian Med Surg 2018 03;32(1):34-39

A male juvenile bald eagle ( Haliaeetus leucocephalus) was admitted to the Wildlife Center of Virginia with a left humeral fracture a large quantity of anthropogenic debris in the ventriculus, a blood lead level of 0.616 ppm, and clinical signs consistent with chronic lead toxicosis. Because of the poor prognosis for recovery and release, the eagle was euthanatized. Read More

View Article

Download full-text PDF

Source
http://www.bioone.org/doi/10.1647/2016-184
Publisher Site
http://dx.doi.org/10.1647/2016-184DOI Listing
March 2018
6 Reads

Reduced regional volumes associated with total psychopathy scores in an adult population with childhood lead exposure.

Neurotoxicology 2018 07 7;67:1-26. Epub 2018 Apr 7.

Imaging Research Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States; Department of Environmental Health, Division of Epidemiology and Biostatistics, University of Cincinnati College of Medicine, Cincinnati, OH, United States; Department of Radiology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, United States.

Childhood lead exposure has been correlated to acts of delinquency and criminal behavior; however, little research has been conducted to examine its potential long term influence on behavioral factors such as personality, specifically psychopathic personality. Neuroimaging studies have demonstrated that the effects of childhood lead exposure persist into adulthood, with structural abnormalities found in gray and white matter regions involved in behavioral decision making. The current study examined whether measurements of adult psychopathy were associated with neuroanatomical differences in structural brain volumes for a longitudinal cohort with measured childhood lead exposure. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuro.2018.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054826PMC
July 2018
13 Reads

Lead in a case of encephalopathy.

BMJ Case Rep 2018 Mar 9;2018. Epub 2018 Mar 9.

Department of Paediatrics, Leeds Teaching Hospitals NHS Trust, Leeds, UK.

A 2-year-old boy with a history of pica was admitted with vomiting and treated overnight for viral tonsillitis. A week later, he presented with a prolonged afebrile seizure and required intubation and ventilation. Antibiotics and acyclovir were started. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2017-222388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847830PMC
March 2018
7 Reads

Extra-Articular Retained Missiles; Is Surveillance of Lead Levels Needed?

Mil Med 2018 03;183(3-4):e107-e113

Uniformed Services University-Walter Reed Department of Surgery, Walter Reed National Military Medical Center, 8901 Wisconsin Avenue, Bethesda, MD 20889.

Background: Although gunshot wounds are relatively common, lead toxicity associated with extra-articular retained missiles (EARMs) is an uncommon, yet potentially devastating, complication. Although the risk of lead toxicity with intra-articular retained missiles is well known, EARMs are routinely left in situ or only removed in selected circumstances secondary to the relatively rare occurrence of complications.

Methods: We first describe a patient with systemic lead poisoning associated with retained lead fragments after a gunshot-induced left femoral shaft fracture. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/milmed/usx076DOI Listing
March 2018
12 Reads

Lead Poisoning: Myoclonus Following Welding Exposure.

Acta Med Port 2017 12 29;30(12):889. Epub 2017 Dec 29.

Instituto de Epilepsia y Parkinson del Eje Cafetero SA. Pereira. Colombia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.20344/amp.9398DOI Listing
December 2017
12 Reads

From the Cover: 7,8-Dihydroxyflavone Rescues Lead-Induced Impairment of Vesicular Release: A Novel Therapeutic Approach for Lead Intoxicated Children.

Toxicol Sci 2018 01;161(1):186-195

Department of Environmental & Occupational Health, Robert Stempel College of Public Health & Social Work, Florida International University, Miami, Florida 33199.

Childhood lead (Pb2+) intoxication is a public health problem of global proportion. Lead exposure during development produces multiple effects on the central nervous system including impaired synapse formation, altered synaptic plasticity, and learning deficits. In primary hippocampal neurons in culture and hippocampal slices, Pb2+ exposure inhibits vesicular release and reduces the number of fast-releasing sites, an effect associated with Pb2+ inhibition of NMDA receptor-mediated trans-synaptic Brain-Derived Neurotrophic Factor (BDNF) signaling. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/toxsci/kfx210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837521PMC
January 2018
6 Reads

Feasibility of a portable X-ray fluorescence device for bone lead measurements of condor bones.

Sci Total Environ 2018 Feb 4;615:398-403. Epub 2017 Oct 4.

Harvard T.H. Chan School of Public Health, Boston, MA 02215, USA.

Lead based ammunition is a primary source of lead exposure, especially for scavenging wildlife. Lead poisoning remains the leading cause of diagnosed death for the critically endangered California condors, which are annually monitored via blood tests for lead exposure. The results of these tests are helpful in determining recent exposure in condors and in defining the potential for exposure to other species including humans. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00489697173246
Publisher Site
http://dx.doi.org/10.1016/j.scitotenv.2017.09.123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688005PMC
February 2018
8 Reads

An Unusual Case of Acute Psychosis With Obsessive-Compulsive Features Following Arsenic Poisoning.

J Psychiatr Pract 2017 09;23(5):382-385

WU, ABDEL-GAWAD, and GHARBAOUI: Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center, Houston, TX TEIXEIRA, PIGOTT: Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center, and University of Texas Harris County Psychiatric Center, Houston, TX.

Arsenic exposure, particularly the chronic type, can lead to poisoning with manifestations presenting in multiple organ systems. However, acute psychosis is not a commonly described manifestation of arsenic exposure. In this report, we present the case of a patient who developed acute psychosis with hallucinations, disorganized thinking, and obsessive-compulsive symptoms following chronic occupational arsenic exposure. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PRA.0000000000000254DOI Listing
September 2017
21 Reads

Skeletal Lead Burden of the British Royal Navy in Colonial Antigua.

Int J Osteoarchaeol 2017 Jul-Aug;27(4):672-682. Epub 2017 May 3.

Department of AnthropologyLakehead UniversityThunder BayONCanada.

Lead (Pb) has been known to be a cause of human poisoning since ancient times, but despite this, it was a widely used metal in the European colonial period. In this study, the relationship between Pb exposure and the demographic variables ancestry and age was explored by comparing the bone Pb levels of individuals that were of either African or European ancestry, excavated from a British Royal Navy hospital cemetery (1793-1822 CE) at English Harbour in Antigua, West Indies. More direct comparisons of Pb levels between the two ancestral groups were possible in this study because of the unsegregated nature of this cemetery. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/oa.2589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574018PMC
May 2017
7 Reads

Cognitive sequelae of lithium intoxication: a case report.

Int Psychogeriatr 2017 10 24;29(10):1747-1751. Epub 2017 Apr 24.

Department of Psychiatry,Psychosomatic Medicine and Psychotherapy,University Hospital Frankfurt/Goethe University,Frankfurt am Main,Germany.

Lithium intoxication is known to induce cognitive deficits along with motor and behavioral changes, even in association with normal serum levels. However, cases with comprehensive neuropsychological assessment of the deficits are rare. In our patient, we initially found severe cognitive deficits, including apraxia and visuo-constructive problems, and temporo-parietal FDG-PET hypometabolism. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S1041610217000540DOI Listing
October 2017
21 Reads

Severe Systemic Lead Toxicity Resulting From Extra-Articular Retained Shrapnel Presenting as Jaundice and Hepatitis: A Case Report and Review of the Literature.

Mil Med 2017 03;182(3):e1843-e1848

Department of Preventive Medicine and Public Health, Blanchfield Army Community Hospital, 2576 23rd Street, Fort Campbell, KY 42223.

Introduction: Despite greater than 60,000 nonfatal firearm injuries per year in the United States, retained shrapnel is a relatively rare cause of systemic lead toxicity with less than 100 cases reported in the medical literature since 1867. While intra-articular retained shrapnel as a cause of lead toxicity is well-described, extra-articular fragments are less well known to cause symptomatic disease.

Case Report: A 31-year-old man initially presented with abdominal pain, constipation, jaundice, and elevated liver transaminases approximately 3 weeks after suffering a left lower extremity injury during athletic activity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7205/MILMED-D-16-00231DOI Listing
March 2017
27 Reads

Severe lead toxicity attributed to bullet fragments retained in soft tissue.

BMJ Case Rep 2017 Mar 8;2017. Epub 2017 Mar 8.

University of Wisconsin-Madison, Wisconsin State Laboratory of Hygiene, Trace Element Research Laboratory, Madison, Wisconsin, USA.

A man aged 30 years presented to an emergency department with a 1 month history of severe abdominal pain, jaundice, constipation, lower extremity weakness and weight loss. A peripheral blood smear was performed that showed basophilic stippling of erythrocytes prompting a blood lead level (BLL) evaluation. The patient had a BLL of >200 µg/dL. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2016-217351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353372PMC
March 2017
11 Reads

Isoniazid Poisoning: A Pediatric Simulation Case for Emergency Medicine Residents.

MedEdPORTAL 2016 Dec 9;12:10515. Epub 2016 Dec 9.

Assistant Residency Director, Department of Emergency Medicine, Emory University School of Medicine; Assistant Professor of Emergency Medicine, Emory University School of Medicine.

Introduction: Seizures in the setting of isoniazid (abbreviated INH, from isonocotinylhydrazide) toxicity can be intractable and persistent despite treatment with the usual status epilepticus (SE) medications. If not recognized in a timely fashion, SE can lead to significant morbidity and mortality. This simulation scenario instructs emergency medicine and pediatric residents and fellows in any year of training on the principles and management strategies of approaching a pediatric patient with SE due to INH toxicity. Read More

View Article

Download full-text PDF

Source
https://www.mededportal.org/publication/10515
Publisher Site
http://dx.doi.org/10.15766/mep_2374-8265.10515DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440414PMC
December 2016
19 Reads

Abdominopelvic CT in a Patient With Seizure, Anemia, and Hypocalcemia.

Gastroenterology 2017 Jan 24;152(1):27-28. Epub 2016 Nov 24.

Toxciological Research Center, Department of Clinical Toxicology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.gastro.2016.08.010DOI Listing
January 2017
4 Reads

Common Symptoms from an Uncommon Infection: Gastrointestinal Anisakiasis.

Can J Gastroenterol Hepatol 2016 9;2016:5176502. Epub 2016 Oct 9.

Division of Gastroenterology, St. Michael's Hospital, University of Toronto, 30 Bond Street, Toronto, ON, Canada M5B 1W8.

Clinicians can be forgiven for thinking of anisakiasis as a rare condition low in the differential diagnosis of abdominal pain. Gastrointestinal anisakiasis is a zoonotic parasitic disease caused by consumption of raw or undercooked seafood infected with nematodes of the genus . Even though the reported cases indicate that this is a rare disease, the true incidence of the disease could be potentially higher than what is reported in the literature as cases can go undiagnosed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2016/5176502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075291PMC
March 2017
24 Reads

Systemic Lead Toxicity Secondary to Retained Intraosseous Bullet A Case Report and Review of Literature.

Bull Hosp Jt Dis (2013) 2016 Sep;74(3):229-33

A 35-year-old female presented to orthopaedic clinic with a chief complaint of chronic left hip pain, beginning 17 years prior when she had sustained a gunshot wound to her left buttock. Imaging demonstrated significant left hip arthritis with a retained projectile in the femoral head. Lead levels were also found to be significantly elevated. Read More

View Article

Download full-text PDF

Source
September 2016
6 Reads

Proximal tubular nephropathy in two dogs diagnosed with lead toxicity.

Authors:
J B King

Aust Vet J 2016 Aug;94(8):280-4

Veterinary Specialist Services, Underwood, Queensland, Australia.

Case Report: Lead toxicity was diagnosed in two dogs presenting with vague clinical symptoms. Complete blood count, biochemical testing and imaging changes showed a metarubricytosis in dog 1, but were largely normal in dog 2. Both dogs had glucosuria and proteinuria on urinalysis consistent with damage to the proximal renal tubules. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/avj.12463DOI Listing
August 2016
4 Reads

Analysis of a distinct speech disorder seen in chronic manganese toxicity following Ephedrone abuse.

Clin Neurol Neurosurg 2016 Aug 31;147:71-7. Epub 2016 May 31.

Department of Neurology, Lviv Regional Clinical Hospital, Ukraine.

Introduction: In the last fifteen years a new cause of chronic manganese toxicity has been recognized. It follows recreational intravenous injections of Ephedrone, synthesized from a cold remedies contained pseudoephedrine. Potassium permanganate is used as an oxidant. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clineuro.2016.05.027DOI Listing
August 2016
34 Reads

Dietary supplement for energy and reduced appetite containing the β-agonist isopropyloctopamine leads to heart problems and hospitalisations.

Food Addit Contam Part A Chem Anal Control Expo Risk Assess 2016 May 19;33(5):749-59. Epub 2016 Apr 19.

a RIKILT-Wageningen UR, Expertise Groups Biosensors & Bioassays and Contaminants & Toxins, WB , Wageningen , the Netherlands.

In 2013 the Dutch authorities issued a warning against a dietary supplement that was linked to 11 reported adverse reactions, including heart problems and in one case even a cardiac arrest. In the UK a 20-year-old woman, said to have overdosed on this supplement, died. Since according to the label the product was a herbal mixture, initial LC-MS/MS analysis focused on the detection of plant toxins. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/19440049.2016.1
Publisher Site
http://dx.doi.org/10.1080/19440049.2016.1167965DOI Listing
May 2016
31 Reads

Correlation of brain Magnetic Resonance Imaging of spontaneously lead poisoned bald eagles (Haliaeetus leucocephalus) with histological lesions: A pilot study.

Res Vet Sci 2016 Apr 23;105:236-42. Epub 2016 Feb 23.

The Raptor Center, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, United States. Electronic address:

Six bald eagles with severe, acute lead poisoning based on blood lead values were analyzed by Magnetic Resonance Imaging (MRI) of the brain and histopathology. The aims of the study were to use MRI to locate brain lesions and correlate the changes in MRI signal with the histological character of the lesions at necropsy. All of the bald eagles presented with neurologic and non-neurologic signs suggestive of severe lead poisoning and had blood lead levels in excess of 1. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.rvsc.2016.02.010DOI Listing
April 2016
31 Reads

A rare case of self-injection of elemental mercury.

BMC Res Notes 2016 Mar 25;9:189. Epub 2016 Mar 25.

National Hospital of Sri Lanka, Colombo, Sri Lanka.

Background: Self-injection of elemental mercury is a rare finding especially in healthy people who are mentally sound. Early detection and removal of mercury from the body by chelation and physical removal of a stored injected site is required to prevent long term toxicity.

Case Presentation: A 15 year old previously healthy girl presented with an acute febrile illness with a generalized maculopapular skin rash for 3 days with a preceding history of self-injection of mercury to both her forearms. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13104-016-1992-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807590PMC
March 2016
36 Reads

Acute Methanol Poisoning: Prevalence and Predisposing Factors of Haemorrhagic and Non-Haemorrhagic Brain Lesions.

Basic Clin Pharmacol Toxicol 2016 Aug 10;119(2):228-38. Epub 2016 Feb 10.

First Faculty of Medicine, Department of Occupational Medicine, Toxicological Information Center, Charles University in Prague and General University Hospital, Prague, Czech Republic.

The purpose was to study the prevalence and predisposing factors of brain lesions in survivors of acute methanol poisoning. Clinical data on 106 patients with methanol poisoning were collected during the Czech mass poisoning outbreak. Of 83 survivors, in 46 (55%) patients, follow-up examinations including magnetic resonance imaging of brain (MR) were performed 3-8 and 24-28 months after discharge from the hospital. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bcpt.12559DOI Listing
August 2016
38 Reads

Protection by Edaravone, a Radical Scavenger, against Manganese-Induced Neurotoxicity in Rats.

J Biochem Mol Toxicol 2016 May 18;30(5):217-23. Epub 2016 Jan 18.

Department of Physiology, School of Medicine, Ege University, Izmir, Turkey.

Manganese (Mn) is a required element for biological systems; however, its excessive exposure may lead to a neurological syndrome known as manganism. The aim of the present study was to assess the toxic effects of subacute exposure of Mn by measuring weight gain, motor performance, and biochemical parameters (complex I activity, lipid peroxides, and protein carbonyls) in brain mitochondria in rats. We also examined whether edaravone (EDA), a radical scavenger, exerts protective effects against Mn-induced neurotoxicity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jbt.21780DOI Listing
May 2016
33 Reads