92 results match your criteria Laugier-Hunziker Syndrome


Laugier-Hunziker Syndrome in an 8-Year-Old Boy with Scleral Melanocytosis, Lingual Pigmentation, Labial Pigmentation, and Melanonychia Striata.

Case Rep Pediatr 2020 17;2020:8267805. Epub 2020 Mar 17.

Department of Dermatology and Skin Sciences, University of British Columbia, Vancouver, British Columbia V5Z 1K1, Canada.

Laugier-Hunziker syndrome is a rare, acquired disorder characterized by mucocutaneous hyperpigmentation and melanonychia striata with no underlying systemic abnormalities. We report an 8-year-old boy with Laugier-Hunziker syndrome who presented with melanonychia striata affecting all the fingernails and toenails, macular pigmentation on the tongue and the lower lip, and scleral melanocytosis. Melanonychia striata rarely affect all the twenty nails, and scleral melanocytosis has rarely been reported in association with Laugier-Hunziker syndrome. Read More

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http://dx.doi.org/10.1155/2020/8267805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103058PMC

Black Maculae between the Toes: A Rare Form of Laugier-Hunziker Syndrome?

Indian J Dermatol 2020 Jan-Feb;65(1):69-70

Department of Dermatology, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China. E-mail:

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http://dx.doi.org/10.4103/ijd.IJD_18_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986122PMC
February 2020

A case of recurrent pigmented macules in Laugier-Hunziker syndrome treated using a Q-switched Nd-YAG laser.

J Cosmet Laser Ther 2019 16;21(7-8):395-397. Epub 2019 Oct 16.

Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Songpa-gu, Republic of Korea.

Laugier-hunziker syndrome (LHS) is a sporadic and acquired melanotic pigmentation of lips and oral mucosa which is not associated with gastrointestinal hamartomas in contrast to Peutz-Jeghers syndrome. Treatment using Q-switched neodymium: yttrium-aluminum-garnet (QS-ND:YAG) laser, Q-switched alexandrite laser and, cryotherapy have been reported. However, to the best of our knowledge, there is no report regarding long-term follow-up for recurrence. Read More

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http://dx.doi.org/10.1080/14764172.2019.1680850DOI Listing
June 2020
1 Read

Laugier-Hunziker syndrome: complete clearance of mucosal lentigines with a single session of Q-Switched Nd:YAG laser.

Authors:
Vivek Nair

J Cosmet Laser Ther 2019 2;21(6):343-345. Epub 2019 Sep 2.

Dr Nair's Skin Clinic & Hair Transplant Centre , Gurgaon , India.

: Laugier-Hunziker (LH) syndrome is a rare condition in which melanocyte overactivity produces lentiginous lesions of the lips and buccal mucosa. : Given the paucity of reports on therapeutic options in LH syndrome, this case is herein reported to show the response to treatment with the Q-Switched Nd:YAG laser in a 32-year-old man with LH Syndrome. : The Q-Switched Nd:YAG laser was used to treat the lentiginous lesions on the mucosal surface of the lower lips using a single pass at 532 nm. Read More

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http://dx.doi.org/10.1080/14764172.2019.1660791DOI Listing
March 2020
2 Reads

Levodopa-induced skin disorders in patients with Parkinson disease: a systematic literature review approach.

Acta Neurol Belg 2019 Sep 23;119(3):325-336. Epub 2019 Jul 23.

1st Department of Neurology and Movement Disorders, National and Kapodistrian University of Athens, Medical School, Aeginition Hospital, 72-74 Vasilissis Sofias Avenue, 11528, Athens, Greece.

The use of levodopa for treatment of Parkinson's disease is a well-established clinical practice. Data about the true incidence and severity of cutaneous complications associated with the use of levodopa are largely lacking. Aim of this review was to evaluate the quality of evidence referring to the skin disorders caused by levodopa treatment for Parkinson's disease. Read More

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http://dx.doi.org/10.1007/s13760-019-01195-3DOI Listing
September 2019
3 Reads

Melanonychia striata: clarifying behind the Black Curtain. A review on clinical evaluation and management of the 21st century.

Int J Dermatol 2019 Nov 21;58(11):1239-1245. Epub 2019 Apr 21.

Departments of Pediatrics, Laboratory Medicine, and Pathology, The University of Alberta, Edmonton, Alberta, Canada.

Melanonychia striata is characterized by a tan, brown, or black longitudinal streak within the nail plate that runs from the proximal nail fold to the distal part of the nail plate. Melanonychia striata is due to increased activity of melanocytes or melanocytic hyperplasia in the nail matrix with subsequently increased melanin deposition in the nail plate. The most common cause of melanonychia striata associated with melanocytic activation is ethnic melanonychia which occurs in dark-skinned individuals. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/ijd.14464
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http://dx.doi.org/10.1111/ijd.14464DOI Listing
November 2019
26 Reads
1.227 Impact Factor

Laugier-Hunziker syndrome in a patient with rheumatoid arthritis.

Reumatologia 2019 28;57(1):63-65. Epub 2019 Feb 28.

Department of Dermatology and Venereology, Akdeniz University School of Medicine, Antalya, Turkey.

Laugier-Hunziker syndrome is a rare benign idiopathic condition characterized by acquired macular pigmentation of the lips and buccal mucosa, often accompanied by melanonychia. Although the etiopathogenesis is not fully known, tyrosine is thought to be responsible for the pathogenesis of enzyme hyperactivity in melanin biosynthesis. We present the case of a 66-year-old woman diagnosed with Laugier-Hunziker syndrome and rheumatoid arthritis. Read More

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https://www.termedia.pl/doi/10.5114/reum.2019.83243
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http://dx.doi.org/10.5114/reum.2019.83243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409823PMC
February 2019
12 Reads

Two cases of Laugier-Hunziker syndrome with thrombocytopenia.

Eur J Dermatol 2018 Dec;28(6):830-831

Department of Dermatology, Seoul National University Bundang hospital, 82 Gumi-ro 173 Beon-Gil, Bundang-gu, Seongnam-si, 463-707, Gyeonggi-do, Korea.

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http://dx.doi.org/10.1684/ejd.2018.3406DOI Listing
December 2018
14 Reads

Mystery behind labial and oral melanotic macules: Clinical, dermoscopic and pathological aspects of Laugier-Hunziker syndrome.

World J Clin Cases 2018 Sep;6(10):322-334

Department of Oral Medicine, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing 210008, Jiangsu Province, China.

Labial and oral melanotic macules are commonly encountered in a broad range of conditions ranging from physiologic pigmentation to a sign of an underlying life-threatening disease. Although Laugier-Hunziker syndrome (LHS) shares some features of labial and oral pigmentation with a variety of conditions, it is a benign and acquired condition, frequently associated with longitudinal melanonychia. Herein, the demographic, clinical, dermoscopic, and pathological aspects of LHS were reviewed comprehensively. Read More

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http://dx.doi.org/10.12998/wjcc.v6.i10.322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163135PMC
September 2018
18 Reads

Laugier-Hunziker syndrome in endocrine clinical practice.

Endocrinol Diabetes Metab Case Rep 2018 26;2018. Epub 2018 Jul 26.

Departments of Endocrinology, Diabetes and Metabolic Diseases.

Laugier-Hunziker syndrome (LHS) is a rare, benign and acquired disorder characterized by hyperpigmentation of the oral cavity and lips along with longitudinal melanonychia. No underlying systemic abnormalities or malignant predisposition is associated with it. In everyday clinical practice, an endocrinologist encounters certain endocrine conditions (e. Read More

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http://dx.doi.org/10.1530/EDM-18-0025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063988PMC
July 2018
54 Reads

Case Report: Dermoscopic features of oral lichen planus - the evolution of mucoscopy.

F1000Res 2018 6;7:284. Epub 2018 Mar 6.

Department of Dermatology, College of Medicine, King Faisal University, Hofuf, Saudi Arabia.

Dermoscopy, a non-invasive technique for cutaneous diagnosis is being increasingly studied in various disorders of the skin, nails and scalp. However, it has been under-utilized for the diagnosis and characterization of mucosal disorders. The dermoscopic characterization of cutaneous lichen planus and its variants has been well documented with Wickham's striae constituting the hallmark of the condition. Read More

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http://dx.doi.org/10.12688/f1000research.14134.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861519PMC
March 2018
34 Reads

Laugier-Hunziker Syndrome Presenting with Metachronous Melanoacanthomas.

Head Neck Pathol 2019 Jun 15;13(2):257-263. Epub 2018 Feb 15.

Department of Oral Diagnostic Sciences, School of Dental Medicine, University at Buffalo, The State University of New York, 355 Squire Hall, 3435 Main Street, Buffalo, NY, 14214-3008, USA.

Laugier-Hunziker syndrome (LHS, also termed idiopathic lenticular mucocutaneous hyperpigmentation) is an unusual condition characterized by progressive pigmentation of the mucous membranes. LHS displays a benign course and is not associated with malignancy. Here we present a case of LHS with a 7-year follow-up. Read More

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http://dx.doi.org/10.1007/s12105-018-0897-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514033PMC
June 2019
13 Reads

Laugier-Hunziker syndrome: A case report.

J Stomatol Oral Maxillofac Surg 2018 Apr 12;119(2):158-160. Epub 2017 Dec 12.

Department of Oral Medicine, Nanjing Stomatological Hospital, Medical School of Nanjing University, 210008 Nanjing, China. Electronic address:

Laugier-Hunziker syndrome (LHS) is a rare, benign, acquired pigmentary condition mainly affecting lips, oral mucosa and acral area, frequently associated with longitudinal melanonychia. Herein, we reported a 45-year-old female case with LHS. The clinical, dermoscopic, histopathologic features of LHS were reviewed and the important differential diagnosis was discussed. Read More

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http://dx.doi.org/10.1016/j.jormas.2017.12.003DOI Listing
April 2018
11 Reads

Laugier-Hunziker syndrome.

Cutis 2017 09;100(3):E17-E19

Department of Dermatology, United States Naval Hospital, Yokosuka, Japan.

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September 2017
12 Reads

Efficacy of surgical laser therapy in the management of oral pigmented lesions: A systematic review.

J Photochem Photobiol B 2017 Aug 15;173:353-359. Epub 2017 Jun 15.

Division of General Dentistry, Eastman Institute for Oral Health, University of Rochester, Rochester, NY, United States.

Background: Oral pigmentation, especially in the gingiva poses esthetic problems. Laser therapy has been widely used for cosmetic therapy in dentistry. The aim of the present study was to systematically review the efficacy of surgical laser therapy (SLT) in the management of oral pigmented lesions (OPL). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10111344173022
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http://dx.doi.org/10.1016/j.jphotobiol.2017.06.016DOI Listing
August 2017
14 Reads

Anaemia with Laugier-Hunziker Syndrome: a diagnostic dilemma.

Singapore Med J 2017 05;58(5):281

Department of Otorhinolaryngology-Head and Neck Surgery, John Hopkins School of Medicine, Baltimore, USA.

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http://dx.doi.org/10.11622/smedj.2017040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435849PMC
May 2017
17 Reads

Laugier-Hunziker syndrome: a case of asymptomatic mucosal and acral hyperpigmentation.

Dermatol Pract Concept 2017 Apr 30;7(2):27-30. Epub 2017 Apr 30.

Department of Dermatology, University Hospital Zurich, Zurich Switzerland.

Laugier-Hunziker syndrome (LHS) is a rare condition characterized by acquired hyperpigmentation involving the lips, oral mucosa, acral surfaces, nails and perineum. While patients with LHS may manifest pigmentation in all of the aforementioned areas, most present with pigmentation localized to only a few of these anatomical sites. We herein report a patient exhibiting the characteristic pigment distribution pattern associated with LHS. Read More

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http://dx.doi.org/10.5826/dpc.0702a05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424658PMC
April 2017
42 Reads

Laugier-Hunziker Syndrome in a Young Female.

Indian Dermatol Online J 2017 Mar-Apr;8(2):148-150

Department of Dermatology, Venereology and Leprology, Institute of Postgraduate Medical Education and Research, Kolkata, West Bengal, India.

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http://dx.doi.org/10.4103/2229-5178.202282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372444PMC
April 2017
15 Reads

Lentiginous phenotypes caused by diverse pathogenic genes (SASH1 and PTPN11): clinical and molecular discrimination.

Clin Genet 2016 10 3;90(4):372-7. Epub 2016 Feb 3.

Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Pathogenic mutations in genes (SASH1 and PTPN11) can cause a rare genetic disorder associated with pigmentation defects and the well-known LEOPARD syndrome, respectively. Both conditions presented with lentiginous phenotypes. The aim of this study was to arrive at definite diagnoses of three Chinese boys with clinically suspected lentigines-related syndromes. Read More

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http://dx.doi.org/10.1111/cge.12728DOI Listing
October 2016
6 Reads

[Laugier-Hunziker syndrome in a patient with Sjögren’s syndrome: Report of one case].

Rev Med Chil 2016 May;144(5):671-4

Laugier-Hunziker syndrome is a rare benign idiopathic condition characterized by acquired macular pigmentation of lips and buccal mucosa, often accompanied with melanonychia. The main concern with this condition is to rule out other differential diagnosis with systemic repercussions and similar hyperpigmentation patterns, such as Peutz-Jeghers syndrome, adrenal insufficiency and melanoma. We report a 58-year-old female with a 20-year history of Sjögren’s syndrome, presenting with melanonychia and hyperpigmentation in the buccal mucosa. Read More

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http://dx.doi.org/10.4067/S0034-98872016000500017DOI Listing
May 2016
18 Reads

Laugier-Hunziker Syndrome Revisited.

Indian J Dermatol 2016 May-Jun;61(3):338-9

Department of Dermatology, Katihar Medical College, Katihar, Bihar, India.

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http://dx.doi.org/10.4103/0019-5154.182429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885197PMC
June 2016
14 Reads

Dermoscopic features of conjunctival, mucosal, and nail pigmentations in a case of Laugier-Hunziker syndrome.

Dermatol Pract Concept 2016 Jan 31;6(1):23-4. Epub 2016 Jan 31.

Department of Pathology, Pamukkale University, Denizli, Turkey.

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http://dx.doi.org/10.5826/dpc.0601a07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758442PMC
January 2016
22 Reads

The role of STK 11 gene testing in individuals with oral pigmentation.

Australas J Dermatol 2017 May 14;58(2):135-138. Epub 2016 Jan 14.

Royal Melbourne Hospital, Familial Cancer Centre, Melbourne, Victoria, Australia.

Peutz-Jeghers syndrome (PJS) is a rare, autosomal dominant condition characterised by mucocutaneous pigmented lesions, gastrointestinal polyposis and a significant risk of cancer. Laugier-Hunziker syndrome (LHS) is a benign condition with similar dermatological features, but with no systemic complications. STK 11 gene testing allows clinicians to differentiate between these two disorders. Read More

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http://dx.doi.org/10.1111/ajd.12443DOI Listing
May 2017
5 Reads

Macular pigmentation complicating irritant contact dermatitis and viral warts in Laugier-Hunziker syndrome.

Authors:
B Bhoyrul J Paulus

Clin Exp Dermatol 2016 Apr 28;41(3):294-6. Epub 2015 Oct 28.

Department of Dermatology, Singleton Hospital, Swansea, UK.

Laugier-Hunziker syndrome (LHS) is a rare acquired disorder characterized by macu-lar pigmentation of the lips and oral mucosa, with frequent longitudinal melanonychia. Involvement of other areas, such as the genitalia and fingers, has rarely been described. LHS is a benign condition with no known systemic manifestations. Read More

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http://dx.doi.org/10.1111/ced.12764DOI Listing
April 2016
13 Reads

Laugier-Hunziker syndrome--Case report.

An Bras Dermatol 2015 May-Jun;90(3 Suppl 1):223-5

Clinical Center of Serbia, Belgrade, RS.

Laugier-Hunziker syndrome is a rare, acquired disorder characterized by lenticular hyperpigmentation of the oral mucosa and longitudinal melanonychia. We present the case of a 63-year-old female with progressive, asymptomatic hyperpigmentation of buccal mucosa and a 7-year history of hyperpigmentation in several fingernails. Laugier-Hunziker syndrome was diagnosed based on the clinical features presented, dermoscopic findings and exclusion of underlying systemic diseases. Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
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http://dx.doi.org/10.1590/abd1806-4841.20153840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540557PMC
January 2016
41 Reads

The Laugier-Hunziker syndrome.

Proc (Bayl Univ Med Cent) 2015 Jan;28(1):41-2

Texas A&M Health Science Center College of Medicine and Baylor University Medical Center at Dallas.

We describe a 46-year-old Hispanic woman who was incidentally found to have hyperpigmentation of the oral mucosa and nails during a routine full body skin examination. The patient reported having these changes for years with no symptoms. A diagnosis of the Laugier-Hunziker syndrome (LHS) was made. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264707PMC
http://dx.doi.org/10.1080/08998280.2015.11929182DOI Listing
January 2015
40 Reads

[Suspicious melanonychia revealing Laugier Hunziker syndrome].

Pan Afr Med J 2015 24;22:291. Epub 2015 Nov 24.

Service de Dermatologie et Vénérologie, CHU Ibn Sina, Université Mohammed V, Rabat Maroc.

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http://dx.doi.org/10.11604/pamj.2015.22.291.8203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769057PMC
December 2016
19 Reads

Refractory Pigmentation Associated with Laugier-Hunziker Syndrome following Er:YAG Laser Treatment.

Case Rep Dent 2013 3;2013:561040. Epub 2013 Dec 3.

Department of Oral Medicine and Surgery, Faculty of Dentistry, Istanbul University, 34093 Istanbul, Turkey.

The present report describes a case of Laugier-Hunziker syndrome (LHS), a rare benign condition. A patient with LHS develops acquired melanotic pigmentation of the lips and buccal mucosa, often with pigmentation of the nails occurring. No systemic symptoms are associated with this syndrome. Read More

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http://dx.doi.org/10.1155/2013/561040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866833PMC
December 2013
10 Reads
1 Citation

Laugier-Hunziker syndrome.

Eur J Dermatol 2013 Apr;23(2):284-5

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http://dx.doi.org/10.1684/ejd.2013.2000DOI Listing
April 2013
14 Reads

Laugier-Hunziker syndrome: case report and review of the literature.

Oral Surg Oral Med Oral Pathol Oral Radiol 2013 Jul 2;116(1):e52-8. Epub 2013 Apr 2.

Department of Oral Pathology and Medicine, Dental School, National and Kapodistrian University of Athens, Athens, Greece.

Laugier-Hunziker syndrome is a rare acquired disorder characterized by diffuse pigmented macules of the oral mucosa. Other mucosal and cutaneous surfaces may be affected, and nail involvement is frequent. A case of Laugier-Hunziker syndrome in a Greek female with multiple buccal and labial mucosal lesions and unusual conjunctival involvement is presented here. Read More

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http://dx.doi.org/10.1016/j.oooo.2012.12.012DOI Listing
July 2013
11 Reads

Pigmented fungiform papillae of the tongue in Laugier disease (or Laugier-Hunziker syndrome).

Authors:
F Urbina E Sudy

Actas Dermosifiliogr 2013 Mar 21;104(2):173-4. Epub 2012 Dec 21.

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http://dx.doi.org/10.1016/j.ad.2012.10.009DOI Listing
March 2013
12 Reads

Response to: «pigmented fungiform papillae of the tongue in Laugier disease (or Laugier-Hunziker syndrome)».

Authors:
J Marcoval

Actas Dermosifiliogr 2013 Mar 20;104(2):174. Epub 2012 Dec 20.

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http://dx.doi.org/10.1016/j.ad.2012.10.007DOI Listing
March 2013
6 Reads

Laugier-Hunziker syndrome: a report of three cases and literature review.

Int J Oral Sci 2012 Dec 23;4(4):226-30. Epub 2012 Nov 23.

Department of Oral Medicine, Institute and Hospital of Stomatology, Nanjing University Medical School, Nanjing, China.

Laugier-Hunziker syndrome (LHS) is an acquired pigmentary condition affecting lips, oral mucosa and acral area, frequently associated with longitudinal melanonychia. There is neither malignant predisposition nor underlying systemic abnormality associated with LHS. Herein, we present three uncommon cases of LHS with possibly new feature of nail pigmentation, which were diagnosed during the past 2 years. Read More

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http://dx.doi.org/10.1038/ijos.2012.60DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633062PMC
December 2012
23 Reads

Laugier-hunziker syndrome in a patient with pancreatic cancer.

Case Rep Dermatol 2012 May 16;4(2):174-6. Epub 2012 Aug 16.

Department of Dermatology, Hietzing Municipal Hospital, Vienna, Austria.

Laugier-Hunziker syndrome is a rare acquired disorder characterized by macular hyperpigmentation of the oral and occasionally genital mucosa as well as longitudinal melanonychia. It is considered a benign condition without systemic manifestation or malignant potential. We report on a woman who concomitantly developed Laugier-Hunziker syndrome and a carcinoma of the pancreas. Read More

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http://dx.doi.org/10.1159/000342070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433014PMC
May 2012
11 Reads

Laugier-Hunziker syndrome.

J Oral Maxillofac Pathol 2012 May;16(2):245-50

Department of Oral Pathology and Microbiology, Maratha Mandal's NG Halgekar Institute of Dental Sciences and Research Centre, Belgaum, Karnataka, India.

Laugier-Hunziker syndrome is a rare acquired disorder characterized by diffuse hyperpigmentation of the oral mucosa and longitudinal melanonychia in adults. They appear as macular lesions less than 5 mm in diameter. Laugier-Hunziker syndrome is considered to be a benign disease with no systemic manifestation or malignant potential. Read More

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http://www.jomfp.in/text.asp?2012/16/2/245/99079
Publisher Site
http://dx.doi.org/10.4103/0973-029X.99079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424942PMC
May 2012
23 Reads

Asymptomatic lower lip hyperpigmentation from Laugier-Hunziker syndrome.

Cutis 2011 Nov;88(5):235-6

Wake Forest Baptist Health, Winston-Salem, North Carolina, USA.

Laugier-Hunziker syndrome is a rare mucocutaneous pigmentary disorder. It is considered benign, but other mucocutaneous pigmentation disorders are in the differential diagnosis and should be ruled out. This report describes a woman with pigmentation of the labial mucosa of the lower lip who was successfully treated with a Q-switched 532-nm laser. Read More

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November 2011
8 Reads

Hyperpigmentation in Laugier-Hunziker syndrome.

CMAJ 2011 Sep 8;183(12):1402. Epub 2011 Aug 8.

Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1503/cmaj.110211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168631PMC
September 2011
6 Reads

Laugier-Hunziker syndrome.

Indian J Dermatol Venereol Leprol 2011 Jul-Aug;77(4):536

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http://dx.doi.org/10.4103/0378-6323.82422DOI Listing
May 2012
12 Reads

Laugier-hunziker syndrome: a rare cause of oral and acral pigmentation.

J Cutan Aesthet Surg 2011 Jan;4(1):58-60

Carolena Skin, Laser & Research Centre, Jalandhar, Punjab, India.

Laugier-Hunziker syndrome (LHS) is an acquired, benign pigmentary skin condition involving oral cavity including lower lip in the form of brown black macules 1-5 mm in size, frequently associated with longitudinal melanonychia. There is no underlying systemic abnormality or malignant predisposition associated with LHS, and therefore the prognosis is good. Important differential diagnoses include Peutz Jeghers syndrome and Addison's disease among other causes of oral and acral pigmentation. Read More

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http://dx.doi.org/10.4103/0974-2077.79199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081490PMC
January 2011
9 Reads

Laugier-Hunziker syndrome: A case report and review of the literature.

Dermatol Online J 2010 Dec 15;16(12). Epub 2010 Dec 15.

Department of Dermatology, Baylor College of Medicine, Houston, Texas, USA.

Laugier-Hunziker syndrome (LHS) is a rare acquired disorder characterized by diffuse macular hyperpigmentation of the oral mucosa and, at times, longitudinal melanonychia. Although LHS is considered a benign disease with no systemic manifestations or malignant potential, it is important to rule out other mucocutaneous pigmentary disorders that do require medical management. Prompt clinical recognition also averts the need for excessive and invasive procedures and treatments. Read More

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December 2010
7 Reads

Dermoscopic features in Laugier-Hunziker syndrome.

J Dermatol 2011 Jan 23;38(1):87-90. Epub 2010 Nov 23.

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http://dx.doi.org/10.1111/j.1346-8138.2010.01077.xDOI Listing
January 2011
12 Reads

Laugier Hunziker syndrome.

Dermatol Online J 2010 Nov 15;16(11):23. Epub 2010 Nov 15.

Department of Dermatology, New York University, New York, NY, USA.

Laugier Hunziker syndrome is a rare disorder that is characterized by adult-onset hyperpigmented macules of the lips, oral cavity, and fingertips. Longitudinal melanonychia is present in the majority of cases. We present a 45-year-old woman with adult-onset hyperpigmented macules of the oral cavity as well as linear melanonychia that involved multiple fingernails. Read More

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November 2010
36 Reads
3 Citations

Do you know this syndrome?

An Bras Dermatol 2010 Sep-Oct;85(5):751-3

Hospital Universitário Getúlio Vargas, Universidade Federal do Amazonas, Manaus, AM, Brasil.

Laugier-Hunziker syndrome is an acquired macular hyperpigmentation of the oral and genital mucosa, often associated with longitudinal melanonychia. We report a case of longitudinal melanonychia on fingernails and toenails, hutchinson's signal and lenticular pigmentation of her lips and oral mucosa. Histopathological analysis is typical and had a broad differential diagnosis. Read More

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http://dx.doi.org/10.1590/s0365-05962010000500029DOI Listing
October 2011
9 Reads

Dermoscopic findings and histological correlation of the acral volar pigmented maculae in Laugier-Hunziker syndrome.

J Dermatol 2010 Nov;37(11):980-4

Department of Dermatology, Universitary Hospital La Paz, Madrid, Spain.

Laugier-Hunziker syndrome (LHS) is an acquired, benign, macular hyperpigmentation of the lips and oral mucosa, often associated with pigmentation of the nails. Volar acral maculae on the palms and fingertips of patients affected by LHS are a typical feature of this rare entity. Dermoscopic examination of these maculae has been described in a previous report, in which authors found a parallel-furrow pattern. Read More

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http://dx.doi.org/10.1111/j.1346-8138.2010.00924.xDOI Listing
November 2010
15 Reads

Laugier-hunziker syndrome: an uncommon cause of oral pigmentation and a review of the literature.

Int J Dent 2010 7;2010:525404. Epub 2010 Jul 7.

Department of Oral Science, University of Bologna, Via San Vitale 59, 40125 Bologna, Italy.

Laugier-Hunziker syndrome is a rare benign condition characterized by diffuse oral hyperpigmentation associated with pigmentation of the nails. The syndrome must be included in the differential diagnosis of diffuse oral pigmentation to exclude other conditions with systemic implications. We describe a 43-year-old white woman with the clinical and histological features of Laugier-Hunziker syndrome associated with toenail pigmentation. Read More

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http://dx.doi.org/10.1155/2010/525404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910470PMC
July 2011
27 Reads

Treatment of Laugier-Hunziker syndrome with the Q-switched alexandrite laser in 22 Chinese patients.

Arch Dermatol Res 2010 Mar 11;302(2):125-30. Epub 2009 Dec 11.

Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.

Laugier-Hunziker syndrome (LHS), a rare, acquired pigmentary disorder of the lips, oral mucosa, and fingers, is known to be an entirely benign disease with no systemic manifestations. In the past, the pigmentation has been treated efficiently in a few patients with the Q-switched neodymium: yttrium-aluminum-garnet (Nd:YAG) laser and the Q-switched alexandrite laser (QSAL). In order to evaluate the efficacy and safety of QSAL on Chinese patients of LHS, we treated 22 patients with QSAL in the past 5 years. Read More

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http://dx.doi.org/10.1007/s00403-009-0930-1DOI Listing
March 2010
28 Reads

Dermoscopic features of pigmentation in Laugier-Hunziker-Baran syndrome.

Dermatol Surg 2010 4;36(1):152-4. Epub 2009 Nov 4.

Department of Dermatology, Graduate School of Medicine, Osaka City University, Osaka, Japan.

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http://dx.doi.org/10.1111/j.1524-4725.2009.01371.xDOI Listing
April 2010
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Dermatoscopy of an invasive melanoma on the upper lip shows possible association with Laugier-Hunziker syndrome.

J Am Acad Dermatol 2008 Nov;59(5 Suppl):S105-8

Department of Dermatology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.

We report mucosal melanoma of the upper lip in a patient affected by the Laugier-Hunziker disease. Using dermatoscopy, two distinct parts were identified in the same mucosal area: nodular (malignant) and macular (benign). A complete surgical excision was performed and the patient has been free of disease for 16 months. Read More

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http://dx.doi.org/10.1016/j.jaad.2008.07.023DOI Listing
November 2008
16 Reads