391 results match your criteria Lattice Degeneration


Vision-Related Functioning in Patients Undergoing Pneumatic Retinopexy vs Vitrectomy for Primary Rhegmatogenous Retinal Detachment: A Post Hoc Exploratory Analysis of the PIVOT Randomized Clinical Trial.

JAMA Ophthalmol 2020 Jun 18. Epub 2020 Jun 18.

Newcastle Eye Centre, Royal Victoria Infirmary, Newcastle upon Tyne, England.

Importance: Although rhegmatogenous retinal detachment (RRD) repair techniques have high anatomical reattachment rates, there may be differences in various aspects of postoperative vision-related quality of life (VRQoL).

Objective: To explore the differences in various aspects of VRQoL between pneumatic retinopexy (PnR) and pars plana vitrectomy (PPV) following RRD repair.

Design, Setting, And Participants: Post hoc exploratory analysis of the the Pneumatic Retinopexy vs Vitrectomy for the Management of Primary Rhegmatogenous Retinal Detachment Outcomes randomized clinical trial conducted between August 2012 and May 2017 at St Michael's Hospital, Toronto, Ontario, Canada. Read More

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http://dx.doi.org/10.1001/jamaophthalmol.2020.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303897PMC

Pregnancy management in a patient with stickler syndrome.

Mol Genet Genomic Med 2020 Jun 1:e1311. Epub 2020 Jun 1.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA, USA.

Background: Stickler syndrome is a collagen disorder that can affect multiple organ systems. It is characterized by ocular abnormalities, hearing loss, midfacial hypoplasia, hypermobility, and joint abnormalities. The phenotypic expression of Stickler syndrome can vary among those affected. Read More

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http://dx.doi.org/10.1002/mgg3.1311DOI Listing

Localized versus 360° intraoperative laser retinopexy in cases of rhegmatogenous retinal detachment with mild-to-moderate grade proliferative vitreoretinopathy.

Eye (Lond) 2020 May 12. Epub 2020 May 12.

Ophthalmology Unit, Department of Surgical, Medical, Molecular and Critical Area Pathology, University of Pisa, Pisa, Italy.

Background/objectives: To compare the efficacy of intraoperative localized and 360° laser retinopexy in cases of rhegmatogenous retinal detachment (RRD) treated with pars plana vitrectomy and air tamponade.

Subjects/methods: In this interventional, prospective, randomized, comparative study, 93 consecutive cases of RRD were enroled. After randomization 48 eyes received circumferential, while 45 underwent localized intraoperative laser retinopexy. Read More

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http://dx.doi.org/10.1038/s41433-020-0950-9DOI Listing
May 2020
1.897 Impact Factor

Outcomes and Complications Associated with Noninfectious Uveitis in Patients Presenting with Rhegmatogenous Retinal Detachment.

Ophthalmol Retina 2020 Feb 28. Epub 2020 Feb 28.

Department of Ophthalmology, University of Colorado School of Medicine, Aurora, Colorado. Electronic address:

Purpose: To evaluate the visual outcomes and complications associated with noninfectious uveitis in patients presenting with a rhegmatogenous retinal detachment (RRD).

Design: Retrospective cohort study.

Participants: A total of 554 eyes of 523 patients presenting for RRD repair at the Department of Ophthalmology, University of Colorado School of Medicine, between July 2011 and September 2016. Read More

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http://dx.doi.org/10.1016/j.oret.2020.02.010DOI Listing
February 2020

Incidence and Risk Factors of Iatrogenic Retinal Breaks: 20-Gauge versus 25-Gauge Vitrectomy for Idiopathic Macular Hole Repair.

J Ophthalmol 2020 13;2020:5085180. Epub 2020 Feb 13.

Department of Ophthalmology, Toho University Ohashi Medical Center, Tokyo, Japan.

Purpose: We compared the incidences of iatrogenic retinal breaks and postoperative retinal detachment between eyes that underwent 20-gauge vitrectomy and those that underwent 25-gauge vitrectomy for idiopathic macular hole repair.

Methods: This retrospective nonrandomized consecutive observational case series included 185 eyes of 183 patients (130 eyes of 129 patients and 55 eyes of 54 patients in the 20- and 25-gauge groups, respectively). We assessed the relationship between the incidence of retinal breaks and postoperative retinal detachment and related this to posterior vitreous detachment and lattice degeneration. Read More

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http://dx.doi.org/10.1155/2020/5085180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040406PMC
February 2020

A deep learning system for identifying lattice degeneration and retinal breaks using ultra-widefield fundus images.

Ann Transl Med 2019 Nov;7(22):618

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.

Background: Lattice degeneration and/or retinal breaks, defined as notable peripheral retinal lesions (NPRLs), are prone to evolving into rhegmatogenous retinal detachment which can cause severe visual loss. However, screening NPRLs is time-consuming and labor-intensive. Therefore, we aimed to develop and evaluate a deep learning (DL) system for automated identifying NPRLs based on ultra-widefield fundus (UWF) images. Read More

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http://dx.doi.org/10.21037/atm.2019.11.28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944533PMC
November 2019

Common variants in the gene are associated with lattice degeneration of the retina in a Japanese population.

Mol Vis 2019 5;25:843-850. Epub 2019 Dec 5.

Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan.

Purpose: Lattice degeneration of the retina is a vitreoretinal disorder characterized by a visible fundus lesion that predisposes the patient to retinal detachment. It has been suggested that collagen type II alpha 1 () gene variants may contribute to the development of disorders associated with retinal detachment. Here we investigated whether gene variants were associated with the risk of lattice degeneration of the retina. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925665PMC

Posterior Vitreous Detachment, Retinal Breaks, and Lattice Degeneration Preferred Practice Pattern®.

Ophthalmology 2020 01 25;127(1):P146-P181. Epub 2019 Sep 25.

Center for Preventative Ophthalmology and Biostatistics, Department of Ophthalmology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1016/j.ophtha.2019.09.027DOI Listing
January 2020

Evaluation of Systematic Reviews of Interventions for Retina and Vitreous Conditions.

JAMA Ophthalmol 2019 Oct 10. Epub 2019 Oct 10.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

Importance: Patient care and clinical practice guidelines should be informed by evidence from reliable systematic reviews. The reliability of systematic reviews related to forthcoming guidelines for retina and vitreous conditions is unknown.

Objectives: To summarize the reliability of systematic reviews on interventions for 7 retina and vitreous conditions, describe characteristics of reliable and unreliable systematic reviews, and examine the primary area in which they appeared to be lacking. Read More

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https://jamanetwork.com/journals/jamaophthalmology/fullartic
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http://dx.doi.org/10.1001/jamaophthalmol.2019.4016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802257PMC
October 2019
4 Reads

Oswestry Disability Index scores correlate with MRI measurements in degenerating intervertebral discs and endplates.

Eur J Pain 2020 Feb 17;24(2):346-353. Epub 2019 Oct 17.

Center for Imaging Research, Medical College of Wisconsin, Milwaukee, WI, USA.

Background: Low back pain (LBP) is a widespread problem and the leading cause of disability worldwide. While the cause of LBP is multifactorial, several studies suggested that inflammatory mediators in damaged subchondral plates of degenerating discs may lead to chemical sensitization and mechanical stimulation, eventually causing pain. The goal of this study was to explore associations between such changes and LBP-related disability using dynamic contrast-enhanced MRI. Read More

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http://dx.doi.org/10.1002/ejp.1490DOI Listing
February 2020
1 Read

Updated chandelier illumination-assisted scleral buckling using 3D visualization system.

Clin Ophthalmol 2019 6;13:1743-1748. Epub 2019 Sep 6.

Department of Ophthalmology, National Organization Kyoto Medical Center, Kyoto, Japan.

Purpose: To assess the updated chandelier illumination-assisted scleral buckle procedures using a 3D visualization system.

Subjects And Methods: We report a single-center, retrospective, consecutive surgical case series of 18 eyes of 16 patients that underwent scleral buckle procedures combining the use of chandelier endoillumination, a noncontact wide-angle viewing system, an anti-drying contact lens, and a recently developed 3D visualization system. The mean age of the patients was 30. Read More

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http://dx.doi.org/10.2147/OPTH.S218975DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735622PMC
September 2019
2 Reads

Coexistence of Peripheral Retinal Diseases with Macular Hole

Turk J Ophthalmol 2019 09;49(4):209-212

Mustafa Kemal University Faculty of Medicine, Department of Ophthalmology, Hatay, Turkey

Objectives: To investigate the frequency of retinal tear, retinal hole, and lattice degeneration in peripheral retinal examination of patients with macular hole.

Materials And Methods: The files of patients who underwent pars plana vitrectomy surgery with a diagnosis of macular hole at Eskişehir Osmangazi University Department of Ophthalmology between 2008 and 2018 were retrospectively analyzed. A total of 106 patients with primary macular hole who underwent peripheral retinal examination were included in the study. Read More

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http://dx.doi.org/10.4274/tjo.galenos.2019.06706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761376PMC
September 2019
1 Read

Structural Evidence for an Octameric Ring Arrangement of SARM1.

J Mol Biol 2019 09 3;431(19):3591-3605. Epub 2019 Jul 3.

The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 5290002, Israel. Electronic address:

SARM1 induces axonal degeneration in response to various insults and is therefore considered an attractive drug target for the treatment of neuro-degenerative diseases as well as for brain and spinal cord injuries. SARM1 activity depends on the integrity of the protein's SAM domains, as well as on the enzymatic conversion of NAD+ to ADPR (ADP Ribose) products by the SARM1's TIR domain. Therefore, inhibition of either SAM or TIR functions may constitute an effective therapeutic strategy. Read More

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http://dx.doi.org/10.1016/j.jmb.2019.06.030DOI Listing
September 2019
1 Read

Prevalence and Associations of Posterior Segment Manifestations in a Cohort of Egyptian Patients with Pathological Myopia.

Curr Eye Res 2019 09 30;44(9):955-962. Epub 2019 Apr 30.

Department of Ophthalmology, Faculty of Medicine, Cairo University , Cairo , Egypt.

: To determine the prevalence of posterior segment manifestations among consecutive patients with pathological myopia attending our University Hospital general ophthalmology clinic and their association with age, refractive error, axial length and each other. : Patients diagnosed with pathological myopia underwent full ophthalmological examination, optical coherence tomography, fluorescein angiography, and ocular ultrasonography. Manifestations detected were recorded for each eye and their prevalence and association with age, refractive error, axial length and each other was determined. Read More

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http://dx.doi.org/10.1080/02713683.2019.1606252DOI Listing
September 2019
8 Reads

Long-term outcomes of patients with myopic traction maculopathy after phacoemulsification for incident cataract.

Eye (Lond) 2019 09 5;33(9):1423-1432. Epub 2019 Apr 5.

Department of Ophthalmology, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, 200031, Shanghai, China.

Purpose: To evaluate the long-term effect of cataract surgery on highly myopic patients with myopic traction maculopathy (MTM) and the risk factors associated with MTM progression.

Methods: Highly myopic patients with cataract and MTM were included. Phacoemulsification surgery was performed on patients who had vision loss below 20/63 and were willing to operation. Read More

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http://dx.doi.org/10.1038/s41433-019-0416-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002422PMC
September 2019
27 Reads

Pneumatic Retinopexy Experience and Outcomes of Vitreoretinal Fellows in the United States: A Multicenter Study.

Ophthalmol Retina 2019 02 20;3(2):140-145. Epub 2018 Sep 20.

Department of Ophthalmology & Vision Science, University of California, Davis, Sacramento, CA.

Objective: To evaluate the outcomes of patients undergoing pneumatic retinopexy (PR) performed by vitreoretinal fellows at 6 academic centers in the United States.

Design: Retrospective, multicenter, consecutive case series.

Participants: 483 patients with primary retinal detachments who underwent PR by 49 vitreoretinal fellows from 6 U. Read More

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http://dx.doi.org/10.1016/j.oret.2018.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435286PMC
February 2019
11 Reads

POSTERIORLY INSERTED VITREOUS BASE: Preoperative Characteristics, Intraoperative Findings, and Outcomes After Vitrectomy.

Retina 2020 May;40(5):943-950

Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts.

Purpose: To determine the preoperative characteristics, intraoperative and postoperative complications, and outcomes of eyes with posteriorly inserted vitreous base.

Methods: In this retrospective, observational, consecutive case series at 2 academic centers, 37 patients were studied who had posteriorly inserted vitreous base noted during vitrectomy. Posteriorly inserted vitreous base was defined as the insertion of the posterior hyaloid membrane being located posterior to the vortex veins. Read More

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http://dx.doi.org/10.1097/IAE.0000000000002482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697230PMC
May 2020
9 Reads

Rhegmatogenous retinal detachment with a giant tear located in the intermediate periphery: Two case reports.

Medicine (Baltimore) 2019 Jan;98(4):e14271

Department of Ophthalmology, Osaka Medical College, Takatsuki-City, Osaka, Japan.

Rationale: We experienced 2 cases of retinal detachment (RD) with giant tears located in the intermediate periphery of the fundus. In this case report, we investigated the clinical characteristics in these 2 cases.

Patient Concerns And Diagnoses: Case 1 involved a 63-year-old male, who became aware of metamorphopsia and decreased visual acuity (VA) in his left eye. Read More

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http://dx.doi.org/10.1097/MD.0000000000014271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358349PMC
January 2019
6 Reads

Marshall and stickler syndrome in one family.

Cesk Slov Oftalmol Winter 2018;74(3):108-111

The authors present the ocular finding in a patient sent to the Department of Paediatric Ophthalmology at the Children's University Hospital - Faculty of Medicine, Comenius University in Bratislava at the age of 3 months, with congenital glaucoma in her right eye and bilateral high myopia. The family anamnesis of the patient shows repeated occurrence of stunted growth, myopia, facial dysmorphia and cataract. The child's mother had high myopia, the mother's brother underwent cataract surgery, the child's grandmother and her sisters and the child's great grandmother had high myopia and glaucoma, and probably underwent cataract surgery at a young age. Read More

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http://www.cs-ophthalmology.cz/en/journal/2018/3/5
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http://dx.doi.org/10.31348/2018/1/5-3-2018DOI Listing
April 2019
28 Reads

Ocular abnormalities and complications in anterior megalophthalmos: a case series.

Eye (Lond) 2019 05 7;33(5):826-832. Epub 2019 Jan 7.

Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Objectives: To describe the clinical and Scheimpflug imaging features in cases of anterior megalophthalmos (AM).

Methods: Retrospective record review was performed for patients with AM who presented between June 2017 and May 2018. Clinical history, slit lamp examination, Scheimpflug imaging indices (Pentacam-HR, Oculus, GmbH), dilated fundus examination and treatment records were reviewed. Read More

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http://dx.doi.org/10.1038/s41433-018-0329-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707321PMC
May 2019
8 Reads
1.897 Impact Factor

LINCOFF RULES ARE NOT FOLLOWED IN RETINAL DETACHMENT WITH POSTERIOR BREAKS AND ATTACHED CORTICAL VITREOUS.

Retin Cases Brief Rep 2019 Winter;13(1):21-24

Vitreo Retina Services, Dr RP Centre for Ophthalmic Sciences, AIIMS, New Delhi, India.

Purpose: 1) To evaluate factors governing flow of subretinal fluid and validate Lincoff rules (LRs) in cases of rhegmatogenous retinal detachment. 2) To identify cases of rhegmatogenous retinal detachment where LRs are not followed.

Method: This was a retrospective study where 253 patients of rhegmatogenous retinal detachment were identified through surgery records. Read More

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http://dx.doi.org/10.1097/ICB.0000000000000522DOI Listing
February 2019
6 Reads

The Pneumatic Retinopexy versus Vitrectomy for the Management of Primary Rhegmatogenous Retinal Detachment Outcomes Randomized Trial (PIVOT).

Ophthalmology 2019 04 22;126(4):531-539. Epub 2018 Nov 22.

Department of Ophthalmology, St. Michael's Hospital, Toronto, Canada; Department of Ophthalmology & Vision Sciences, University of Toronto, Toronto, Canada; Kensington Vision and Research Center, Toronto, Canada. Electronic address:

Purpose: The optimal surgery to repair rhegmatogenous retinal detachment (RRD) is unknown. The purpose of this trial was to compare outcomes of pneumatic retinopexy (PnR) versus pars plana vitrectomy (PPV) for the management of primary RRD.

Design: Prospective, randomized controlled trial. Read More

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http://dx.doi.org/10.1016/j.ophtha.2018.11.014DOI Listing
April 2019
83 Reads
6.135 Impact Factor

Risk factors for retinal breaks during macular hole surgery.

Clin Ophthalmol 2018 9;12:1981-1985. Epub 2018 Oct 9.

Department of Ophthalmology, Toho University Sakura Medical Center, Sakura, Japan,

Purpose: To identify risk factors for retinal breaks during macular hole (MH) surgery.

Patients And Methods: This retrospective, observational, comparative study included the medical records of 364 consecutive patients (382 eyes) who underwent vitrectomy for MH at Toho University Sakura Medical Center between January 2012 and May 2017. The patients comprised 135 men and 229 women with mean age 67. Read More

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http://dx.doi.org/10.2147/OPTH.S181671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6183691PMC
October 2018
3 Reads

Binary colloidal crystals (BCCs): Interactions, fabrication, and applications.

Adv Colloid Interface Sci 2018 Nov 23;261:102-127. Epub 2018 Aug 23.

Department of Chemistry and Biotechnology, Swinburne University of Technology, Hawthorn, Victoria 3122, Australia; Center for Human Tissues and Organs Degeneration, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China; CSIRO Manufacturing, Bayview Avenue, Clayton, Victoria 3168, Australia. Electronic address:

The organization of matter into hierarchical structures is a fundamental characteristic of functional materials and living organisms. Binary colloidal crystal (BCC) systems present a diversified range of nanotopographic structures where large and small colloidal particles simultaneously self-assemble into either 2D monolayer or 3D hierarchical crystal lattices. More importantly, understanding how BCCs form opens up the possibility to fabricate more complex systems such as ternary or quaternary colloidal crystals. Read More

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http://dx.doi.org/10.1016/j.cis.2018.08.005DOI Listing
November 2018
4 Reads

Spectral-domain optical coherence tomography of peripheral lattice degeneration of myopic eyes before and after laser photocoagulation.

J Formos Med Assoc 2019 Mar 24;118(3):679-685. Epub 2018 Aug 24.

Department of Ophthalmology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taiwan. Electronic address:

Purpose: To investigate the microstructural characteristics of lattice degenerations before and after laser photocoagulation in myopic eyes by spectral-domain optical coherence tomography (SD-OCT).

Methods: Twenty-five eyes of 25 consecutive patients at the High Myopia Clinic of the National Taiwan University Hospital were retrospectively reviewed. Myopic eyes with peripheral lattice degeneration were enrolled in the study. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09296646183025
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http://dx.doi.org/10.1016/j.jfma.2018.08.005DOI Listing
March 2019
19 Reads

Choice of Primary Rhegmatogenous Retinal Detachment Repair Method in US Commercially Insured and Medicare Advantage Patients, 2003-2016.

Am J Ophthalmol 2018 12 23;196:82-90. Epub 2018 Aug 23.

Retina Service, Department of Ophthalmology, University of California, San Francisco, San Francisco, California, USA.

Purpose: To evaluate trends for rhegmatogenous retinal detachment (RRD) repair and the influence of patient characteristics on repair type in a large US population including children and adults, between 2003 and 2016.

Design: Retrospective cohort study.

Methods: Setting: Administrative claims for beneficiaries in a large nationwide managed-care network, including Medicare Advantage, employer-sponsored, and commercial insurance. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029394183047
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http://dx.doi.org/10.1016/j.ajo.2018.08.024DOI Listing
December 2018
45 Reads

Prevalence and characteristics of peripheral myopic retinopathy in Guangzhou office workers.

Int J Ophthalmol 2018 18;11(8):1390-1395. Epub 2018 Aug 18.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, Guangdong Province, China.

Aim: To determine the prevalence and characteristics of peripheral myopic retinopathy among a sample of Guangzhou office workers.

Methods: A cross-sectional study of Guangzhou Chinese office works in different departments and units of the Guangzhou Power Supply Bureau, China, in 2016. Myopic retinopathy was recorded and analyzed with a scanning laser ophthalmoscope and by slit-lamp microscopy combined with a three-mirror contact lens. Read More

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http://dx.doi.org/10.18240/ijo.2018.08.22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090121PMC
August 2018
6 Reads

Bilateral, presumed congenital ectropion uveae in a patient with pathologic myopia.

Am J Ophthalmol Case Rep 2018 Sep 20;11:119-120. Epub 2018 Jun 20.

Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, Philadelphia, PA, 19104, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S24519936183001
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http://dx.doi.org/10.1016/j.ajoc.2018.06.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098174PMC
September 2018
22 Reads

MACULAR VORTEX VEIN IN A HIGHLY MYOPIC EYE IMAGED BY OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY.

Retin Cases Brief Rep 2018 Aug 6. Epub 2018 Aug 6.

Department of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, New York.

Purpose: To report a case of macular vortex vein imaged with indocyanine green angiography, spectral domain optical coherence tomography, and optical coherence tomography angiography.

Methods: Observational case report.

Results: A 51-year-old myopic man presented with the complaint of a floater in his left eye for the previous 2 weeks. Read More

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http://dx.doi.org/10.1097/ICB.0000000000000808DOI Listing
August 2018
10 Reads

Dysregulation of human NEFM and NEFH mRNA stability by ALS-linked miRNAs.

Mol Brain 2018 07 20;11(1):43. Epub 2018 Jul 20.

Molecular Medicine Group, Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.

Neurofilaments (NFs) are the most abundant cytoskeletal component of vertebrate myelinated axons. NFs function by determining axonal caliber, promoting axonal growth and forming a 3-dimensional lattice that supports the organization of cytoplasmic organelles. The stoichiometry of NF protein subunits (NFL, NFM and NFH) has to be tightly controlled to avoid the formation of NF neuronal cytoplasmic inclusions (NCIs), axonal degeneration and neuronal death, all pathological hallmarks of amyotrophic lateral sclerosis (ALS). Read More

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http://dx.doi.org/10.1186/s13041-018-0386-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054723PMC
July 2018
30 Reads

The Prevalence and Associations of Peripheral Retinopathy: Baseline Study of Guangzhou Office Computer Workers.

J Ophthalmol 2018 20;2018:2358690. Epub 2018 Jun 20.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, China.

Purpose: To determine the prevalence of peripheral retinopathy and its associated risk factors among a sample of Guangzhou office computer workers.

Methods: A cross-sectional study of Guangzhou Chinese computer workstations and operators in different departments and units of the Guangzhou Power Supply Bureau, China, in 2016. Peripheral retinopathy was recorded and analyzed using a scanning laser ophthalmoscope (SLO; Optos, Daytona, United Kingdom) and slit-lamp microscopy combined with a three-mirror contact lens. Read More

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http://dx.doi.org/10.1155/2018/2358690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031160PMC
June 2018
30 Reads

Bilateral rhegmatogenous retinal detachment due to unusual retinal degeneration in Down syndrome: A case report.

Medicine (Baltimore) 2018 Jun;97(22):e10896

Department of Ophthalmology, Osaka Medical College, Takatsuki-City, Osaka, Japan.

Rationale: The aim of this study was to report a case of Down syndrome (DS) complicated with bilateral retinal detachment (RD) due to unusual retinal degeneration.

Patient Concerns: A 9-year-old girl complained of bilateral visual disturbance during a follow-up examination for myopia and strabismus.

Diagnoses: Slit-lamp examination revealed moderate posterior subcapsular cataract in both eyes. Read More

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http://Insights.ovid.com/crossref?an=00005792-201806010-0004
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http://dx.doi.org/10.1097/MD.0000000000010896DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392586PMC
June 2018
5 Reads

PREDICTIVE FACTORS FOR PROLIFERATIVE VITREORETINOPATHY FORMATION AFTER UNCOMPLICATED PRIMARY RETINAL DETACHMENT REPAIR.

Retina 2019 Aug;39(8):1488-1495

VitreoRetinal Surgery PA, Minneapolis, Minnesota.

Purpose: To determine predictive factors of proliferative vitreoretinopathy (PVR) formation after uncomplicated primary retinal detachment repair.

Methods: Retrospective, single-center, case-control study of 74 consecutive patients with (37 eyes) and without (37 eyes) PVR formation after undergoing uncomplicated primary surgery for retinal detachment repair. Logistic regression was used to assess factors associated with PVR formation. Read More

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http://dx.doi.org/10.1097/IAE.0000000000002184DOI Listing
August 2019
18 Reads

Out-of-plane band structure of a two-dimensional dispersive photonic crystal.

Opt Lett 2018 May;43(10):2360-2363

We calculated the out-of-plane band structure of a two-dimensional dispersive photonic crystal (PC). To achieve this goal, the plane wave expansion method was implemented in conjunction with a numerical algorithm, the dispersive photonic crystal iterative method. The PC is an array of circular cross-sectional dispersive MgO Lorentz single-pole rods in a square lattice. Read More

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http://dx.doi.org/10.1364/OL.43.002360DOI Listing
May 2018
6 Reads

PAR-Complex and Crumbs Function During Photoreceptor Morphogenesis and Retinal Degeneration.

Authors:
Franck Pichaud

Front Cell Neurosci 2018 29;12:90. Epub 2018 Mar 29.

Medical Research Council, Laboratory for Molecular Cell Biology, University College London, London, United Kingdom.

The fly photoreceptor has long been used as a model to study sensory neuron morphogenesis and retinal degeneration. In particular, elucidating how these cells are built continues to help further our understanding of the mechanisms of polarized cell morphogenesis, intracellular trafficking and the causes of human retinal pathologies. The conserved PAR complex, which in flies consists of Cdc42-PAR6-aPKC-Bazooka, and the transmembrane protein Crumbs (Crb) are key players during photoreceptor morphogenesis. Read More

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http://dx.doi.org/10.3389/fncel.2018.00090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884931PMC
March 2018
4 Reads

Dark Rearing Does Not Prevent Rod Oxidative Stress In Vivo in Pde6brd10 Mice.

Invest Ophthalmol Vis Sci 2018 03;59(3):1659-1665

Department of Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, Michigan, United States.

Purpose: In cyclic light-reared Pde6brd10 mice, rod cell oxidative stress contributes to the degenerative phenotype. Dark rearing Pde6brd10 mice slows but does not prevent atrophy. This suggests that outer retinal oxidative stress occurs in Pde6brd10 mice independent of light exposure, a hypothesis tested in this study. Read More

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http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.1
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http://dx.doi.org/10.1167/iovs.17-22734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868999PMC
March 2018
22 Reads

Peripheral retinal changes in highly myopic young Asian eyes.

Acta Ophthalmol 2018 Nov 25;96(7):e846-e851. Epub 2018 Mar 25.

Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.

Purpose: To determine the type and prevalence of peripheral retinal changes and its relationship with axial length (AL) in a population of young Asian adult males.

Methods: This was a cross-sectional study of male subjects aged between 19 and 25 years old. High myopes [spherical equivalent refraction, (SER) < -6. Read More

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http://dx.doi.org/10.1111/aos.13752DOI Listing
November 2018
20 Reads

RETINAL NEOVASCULARIZATION FROM A PATIENT WITH CUTIS MARMORATA TELANGIECTATICA CONGENITA.

Retin Cases Brief Rep 2018 Mar 14. Epub 2018 Mar 14.

Department of Ophthalmology, Henry Ford Hospital, Detroit, Michigan.

Purpose: To report a rare case of peripheral retinal neovascularization in a patient diagnosed with cutis marmorata telangiectatica congenita (CMTC).

Methods: Observational case report.

Results: A 16-year-old girl was referred to clinic for retinal evaluation. Read More

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http://dx.doi.org/10.1097/ICB.0000000000000736DOI Listing
March 2018
12 Reads

Spin-lock imaging of early tissue pH changes in ischemic rat brain.

NMR Biomed 2018 04 9;31(4):e3893. Epub 2018 Feb 9.

Vanderbilt University Institute of Imaging Science, Vanderbilt University, Nashville, TN, USA.

We have previously reported that the dispersion of spin-lattice relaxation rates in the rotating frame (R ) of tissue water protons at high field can be dominated by chemical exchange contributions. Ischemia in brain causes changes in tissue pH, which in turn may affect proton exchange rates. Amide proton transfer (APT, a form of chemical exchange saturation transfer) has been shown to be sensitive to chemical exchange rates and able to detect pH changes non-invasively following ischemic stroke. Read More

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http://dx.doi.org/10.1002/nbm.3893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854549PMC
April 2018
4 Reads

Retinal Detachment in 31 Eyes with Retinitis Pigmentosa.

Ophthalmol Retina 2018 01 24;2(1):10-16. Epub 2017 May 24.

Shri BhagwanMahavir Vitreoretinal Services, Sankara Nethralaya, Chennai, India.

Objective: To describe clinical features and treatment outcomes of retinal detachment (RD) in eyes with retinitis pigmentosa (RP).

Design: Single-center, retrospective, interventional case series.

Subjects: All RP patients with RD examined between April 2003 and December 2013 and minimum 2 months of follow-up. Read More

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http://dx.doi.org/10.1016/j.oret.2017.03.012DOI Listing
January 2018
5 Reads

Anterograde Transport in Axons of the Retinal Ganglion Cells and its Relationship to the Intraocular Pressure during Aging in Mice with Hereditary Pigmentary Glaucoma.

Curr Eye Res 2018 04 28;43(4):539-546. Epub 2017 Dec 28.

a Mossakowski Medical Research Centre , Polish Academy of Sciences , Warsaw , Poland.

Purpose: To establish a relationship between impairment of the anterograde axonal transport (AAT) in the axons of the retinal ganglion cells and the intraocular pressure (IOP) during aging in mice with hereditary glaucoma.

Methods: Quantitative in vivo approach based on manganese enhanced magnetic resonance imaging was developed in order to evaluate AAT in 3-, 6-, and 14-month old DBA/2J mice that develop age-dependent pigmentary glaucoma or age-matched C57Bl/6 mice that do not develop any retinal disease. Unilateral intravitreous administration of MnCl solution was followed 24 h later by MRI performed to obtain spin-lattice relaxation times (T) for regions of interest encompassing the superior colliculi (SC) and the lateral geniculate nuclei (LGN). Read More

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https://www.tandfonline.com/doi/full/10.1080/02713683.2017.1
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http://dx.doi.org/10.1080/02713683.2017.1416147DOI Listing
April 2018
8 Reads

IDIOPATHIC MULTIFOCAL CHOROIDITIS PRESENTING WITH A TRANSIENT PERIPAPILLARY WHITE RING.

Retin Cases Brief Rep 2018 Fall;12 Suppl 1:S81-S86

LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear and Throat Hospital, New York, New York.

Purpose: We describe with multimodal imaging the presentation and follow-up for a patient with idiopathic multifocal choroiditis and a transient peripapillary white ring.

Methods: Case report.

Results: A 39-year-old Asian woman was initially seen for an evaluation of lattice degeneration in 2015. Read More

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http://dx.doi.org/10.1097/ICB.0000000000000663DOI Listing
October 2018
7 Reads

Reactive Retinal Astrocytic Tumor (Focal Nodular Gliosis): Report of the Clinical Spectrum of 3 Cases.

Ocul Oncol Pathol 2017 Sep 23;3(3):235-239. Epub 2017 Mar 23.

Anatomic Pathology, Cleveland Clinic, Cleveland, Ohio, USA.

Purpose: To report 3 cases providing insight into clinical progression of reactive retinal astrocytic tumor.

Methods: The clinical, imaging, and when available, the cytologic features of 3 cases of reactive retinal astrocytic tumor (focal nodular gliosis) were reviewed.

Results: A 6-year-old female, a 49-year-old man, and a 39-year-old man each developed a white retinal mass associated with laser photocoagulation, lattice degeneration, and treatment of a presumed vascular tumor, respectively. Read More

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http://dx.doi.org/10.1159/000455151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649314PMC
September 2017
16 Reads

Acquired Nonpigmented Vitreous Cyst Associated With Lattice Degeneration.

Ophthalmic Surg Lasers Imaging Retina 2017 10;48(10):856-858

A 63-year-old male presented with a round-shaped floater and visual obscuration in the right eye. Clinical evaluation showed a nonpigmented vitreous cyst connected to a lattice degeneration by a stalk. Immunostaining of the vitreous cyst obtained from vitrectomy showed its origin of retinal neuroepithelium. Read More

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http://dx.doi.org/10.3928/23258160-20170928-13DOI Listing
October 2017
17 Reads

Niobium Doped Lanthanum Strontium Ferrite as A Redox-Stable and Sulfur-Tolerant Anode for Solid Oxide Fuel Cells.

ChemSusChem 2018 01 29;11(1):254-263. Epub 2017 Nov 29.

Department of Physics, Harbin Institute of Technology, 92 Xi Dazhi Street, Harbin, Heilongjiang, 150001, P.R. China.

The Nb-doped lanthanum strontium ferrite perovskite oxide La Sr Fe Nb O (LSFNb) is evaluated as an anode material in a solid oxide fuel cell (SOFC). The effects of Nb partial substitution in the crystal structure, the electrical conductivity, and the valence of Fe ions are studied. LSFNb exhibits good structural stability in a severe reducing atmosphere at 800 °C, suggesting that high-valent Nb can effectively promote the stability of the lattice structure. Read More

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http://dx.doi.org/10.1002/cssc.201701638DOI Listing
January 2018
54 Reads

Rational Design of Cobalt-Iron Selenides for Highly Efficient Electrochemical Water Oxidation.

ACS Appl Mater Interfaces 2017 Oct 20;9(39):33833-33840. Epub 2017 Sep 20.

School of Optical and Electronic Information, Huazhong University of Science and Technology , Wuhan 430074, P. R. China.

Exploring active, stable, earth-abundant, low-cost, and high-efficiency electrocatalysts is highly desired for large-scale industrial applications toward the low-carbon economy. In this study, we apply a versatile selenizing technology to synthesize Se-enriched CoFeSe catalysts on nickel foams for oxygen evolution reactions (OERs) and disclose the relationship between the electronic structures of CoFeSe (via regulating the atom ratio of Co/Fe) and their OER performance. Owing to the fact that the electron configuration of the CoFeSe compounds can be tuned by the incorporated Fe species (electron transfer and lattice distortion), the catalytic activity can be adjusted according to the Co/Fe ratios in the catalyst. Read More

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http://dx.doi.org/10.1021/acsami.7b08917DOI Listing
October 2017
72 Reads

Cost-Utility of Evaluation for Posterior Vitreous Detachment and Prophylaxis of Retinal Detachment.

Ophthalmology 2018 01 18;125(1):43-50. Epub 2017 Jul 18.

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida. Electronic address:

Purpose: To evaluate the costs and cost-utility of examination for posterior vitreous detachment (PVD) and treatment of associated pathology, and of managing various other peripheral retinal disorders to prevent retinal detachment (RD).

Design: A decision analysis model of cost-utility.

Participants: There were no participants. Read More

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http://dx.doi.org/10.1016/j.ophtha.2017.06.019DOI Listing
January 2018
27 Reads

Ophthalmological findings in Cameroonian boxers.

Clin Ophthalmol 2017 12;11:1121-1126. Epub 2017 Jun 12.

Eye Department, University of Yaoundé I.

Background: The purpose of this prospective, noncomparative consecutive study was to examine active and retired amateur boxers in order to evaluate the nature and incidence of ocular pathologic conditions related to the boxing practice.

Results: A total of 35 boxers were included in this study. The mean age of the boxers was 28. Read More

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http://dx.doi.org/10.2147/OPTH.S134173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476758PMC
June 2017
53 Reads

THE IMPORTANCE OF THE PERIPHERAL RETINA IN PATIENTS WITH CENTRAL SEROUS CHORIORETINOPATHY.

Retina 2018 Mar;38(3):578-584

Department of Ophthalmology, Faculty of Medicine, Ege University, Izmir, Turkey.

Purpose: This research investigated the peripheral retinas of patients with central serous chorioretinopathy (CSCR).

Methods: Sixty patients with CSCR and 60 age- and gender-matched controls were included in this prospective cross-sectional study. All 120 participants underwent ocular examinations and peripheral retinal evaluations using a Goldmann three-mirror lens. Read More

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http://dx.doi.org/10.1097/IAE.0000000000001574DOI Listing
March 2018
19 Reads
2 Citations
3.240 Impact Factor

CLINICAL FEATURES OF AFFECTED AND UNDETACHED FELLOW EYES IN PATIENTS WITH FEVR-ASSOCIATED RHEGMATOGENOUS RETINAL DETACHMENT.

Retina 2017 Mar;37(3):585-591

State Key Laboratory of Ophthalmology, Retina Division, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

Purpose: To report the clinical characteristics of the affected and fellow eyes in patients with familial exudative vitreoretinopathy-associated rhegmatogenous retinal detachment (FEVR-RRD).

Methods: This was a retrospective observational case series. The affected and fellow eyes were given complete examinations. Read More

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http://dx.doi.org/10.1097/IAE.0000000000001171DOI Listing
March 2017
23 Reads