Anasthesiol Intensivmed Notfallmed Schmerzther 2017 Oct 19;52(10):704-715. Epub 2017 Oct 19.

The diagnostic evaluation of perioperative anaphylaxia is of great importance for the medical care of the affected persons in the context of renewed interventions in general anesthesia. The most frequent triggers include muscle relaxants, antibiotics, latex and analgesics of the type of the cyclooxygenase inhibitors, but other perioperatively administered drugs such as opioids, anesthetics, benzodiazepines, dyes, disinfectants and even corticosteroids or drug additives may also be the cause in rare cases. The most important aim is therefore the identification of the responsible drug, for which a near-time allergological diagnosis should be carried out within the first 4 weeks to 6 months after the reaction. Read More

Medicina (B Aires) 2017 ;77(5):382-387

Unidad de Alergia, Asma e Inmunología Clínica, Buenos Aires, Argentina.

Anaphylaxis during anesthesia is an unpredictable, severe, and rare reaction. It has an incidence of 1/10 000 to 1/20 000 surgeries. In most series, the responsible drugs include neuromuscular blocking agents, latex, or antibiotics. Read More

Neurourol Urodyn 2017 Sep 26. Epub 2017 Sep 26.

Service des Maladies de l'Appareil Digestif, CHRU Pontchaillou, Université de Rennes 1, Rennes, France.

Aims: The prevalence rate of severe fecal incontinence (FI) in adults with spina bifida (SB) is high. The physiological basis of FI in SB has not been clearly established, which contributes to inadequate care. The aim was to better characterize a large cohort of adults with special consideration of anorectal physiology. Read More

Curr Treat Options Allergy 2017 3;4(3):312-319. Epub 2017 Jun 3.

Allergy and Respiratory Research Group, Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Medical School Doorway 3, Teviot Place, Edinburgh, EH8 9AG UK.

Idiopathic anaphylaxis is a rare life-threatening disorder with symptoms similar to other forms of anaphylaxis. There is lack of a robust evidence base underpinning the treatment of anaphylaxis and even less so for idiopathic anaphylaxis. Much of the evidence therefore comes from relatively small case series and expert opinion. Read More

J Allergy Clin Immunol Pract 2017 Sep - Oct;5(5):1212-1216

Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

Latex allergy emerged as an epidemic of anaphylaxis, occupational asthma, and clinical dilemmas in the 1980s. A systematic recognition, investigation, discovery, epidemiology, and prevention strategy followed. International attention and collaborations of investigators, government agencies, manufacturing, and health policy resulted in near elimination of a global epidemic. Read More

J Eur Acad Dermatol Venereol 2017 Aug 24. Epub 2017 Aug 24.

Chair of Dermatology, Sexually Transmitted Diseases and Imuunodermatology, Faculty of Medicine, Nicolaus Copernicus University in Torun, Bydgoszcz, Poland.

Background: Allergic reaction to seminal plasma was described decades ago. In USA, only tens of thousands women are estimated to be affected. Not only seminal plasma but also cervicovaginal fluid contains sex-restricted antigens, yet allergy to cervicovaginal fluid has never been reported in medical literature. Read More

Clin Exp Allergy 2017 Oct 7;47(10):1318-1330. Epub 2017 Sep 7.

Pharmacy Department, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

Background: Guidelines for investigation of perioperative drug allergy exist, but the quality of services is unknown. Specialist perioperative anaphylaxis services were surveyed through the Royal College of Anaesthetists 6(th) National Audit Project.

Objectives: We compare self-declared UK practice in specialist perioperative allergy services with national recommendations. Read More

NASN Sch Nurse 2017 Nov 4;32(6):343-345. Epub 2017 Aug 4.

Director of Education, Allergy & Asthma, Network.

Providing a safe environment for students at risk for anaphylaxis from a latex allergy requires care coordination and collaboration of all members of the school community. Strategies for allergy management include educating the school community, identifying potential exposure to latex, preparing to respond in an emergency, and creating a plan for the future. With the student at the center of sound planning, the school can provide a secure and healthy environment. Read More

J Investig Allergol Clin Immunol 2017 Aug 1. Epub 2017 Aug 1.

IMMA. Facultad de Medicina. Universidad CEU San Pablo, Madrid, Spain.

Profilin is a protein present in all eukaryotic cells, and is responsible for the cross-reactivity between pollen, latex and plant foods. It has been classically acknowledged as a minor or nearly irrelevant allergen, although recent data are changing this conception. The objective of this manuscript is to comprehensively review the published data on the role of this ubiquitous allergen in pollen, latex and plant food allergy. Read More

Allergol Immunopathol (Madr) 2017 Jul 24. Epub 2017 Jul 24.

Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran. Electronic address:

Introduction: Food allergy refers to abnormal reactions of the body caused by an immune system response to food. This study was conducted aiming to investigate allergy to food allergens in children with food allergies.

Materials And Methods: This study was conducted as a cross-sectional one on 304 children aged six months to seven years with food allergies admitted to the tertiary referral hospital in Kurdistan Province - Iran, during 2014-2015. Read More

Chem Biol Interact 2017 Aug 12;274:138-149. Epub 2017 Jul 12.

Universidade Federal do Ceará, Departamento de Bioquímica e Biologia Molecular, Fortaleza, Ceará CEP 60.440-970, Brazil. Electronic address:

Many thousands of plants are disseminated worldwide in traditional and folk medicines based on the belief that their leaves, roots, seeds, bark or secretions, when adequately handled, can treat, alleviate or ameliorate numerous disease symptoms. Calotropis procera (Apocynaceae) is a popular medicinal plant and the claims of this shrub's phytomedicinal properties have been scientifically validated. In this study, further prospects towards the in vivo toxicity and oral immunological tolerance of phytomodulatory proteins isolated from the latex of C. Read More

Biomed Res Int 2017 19;2017:9573021. Epub 2017 Jun 19.

Department of Chemistry, Faculty of Science, University of Colombo, 03 Colombo, Sri Lanka.

Natural rubber latex (NRL) allergy is caused by the extractable latex proteins in dipped rubber products. It is a major concern for the consumers who are sensitive to the allergenic extractable proteins (EP) in products such as NRL gloves. Objective of this research was to develop an economical method to reduce the EP in finished dipped NRL products. Read More

Asian Cardiovasc Thorac Ann 2017 Jan 1:218492317721412. Epub 2017 Jan 1.

1 Department of Cardiothoracic and Vascular Surgery, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.

Background Recurrent pneumothorax is one of the most common complications after thoracostomy tube removal. The purpose of this study was to assess the optimal method of thoracostomy tube removal by comparing party balloon-assisted Valsalva and classic Valsalva techniques. Methods Trauma patients with indications for tube thoracostomy from 2014 to 2015 were recruited. Read More

Clin Rev Allergy Immunol 2017 Jun 26. Epub 2017 Jun 26.

Department of Internal Medicine, Section of Immunoallergology and Respiratory Diseases, University of Florence, Florence, Italy.

The exact prevalence of hypersensitivity reactions related to sexual behaviours is not known; however, they heavily impact on the quality of life and of sex life of affected patients. In fact, not only common respiratory and skin allergies, such as asthma, rhinitis, urticaria and atopic dermatitis, but also food and drug allergy have been found to negatively affect the quality of sex life. Allergic diseases impact on the sexual function in both physical and psychological ways, representing one of the main complaints of a considerable proportion of patients. Read More

Antioxidants (Basel) 2017 May 18;6(2). Epub 2017 May 18.

Molecular Biology and Genomics Laboratory, Department of Botany, Berhampur University, Berhampur 760007, Odisha, India.

Zinc oxide nanoparticles (ZnONP-GS) were synthesised from the precursor zinc acetate (Zn(CH₃COO)₂) through the green route using the milky latex from milk weed (Calotropis gigantea L. R. Br) by alkaline precipitation. Read More

J Allergy Clin Immunol Pract 2017 May - Jun;5(3):587-592

Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass.

Perioperative anaphylaxis is an iatrogenic clinical condition, most often after anesthetic induction. Several mechanisms are implicated, including IgE- and non-IgE-mediated mechanisms. Perioperative anaphylaxis tends to be severe and has a higher mortality rate than anaphylaxis in other settings. Read More

Ann Allergy Asthma Immunol 2017 May;118(5):603-607

Unit of Occupational Medicine, University of Trieste, Trieste, Italy.

Background: Atopic diseases have increased since the second half of the previous century. Atopic workers are at higher risk to be sensitized to latex, and the first years of exposure are supposed to be especially risky.

Objective: To assess atopic status and rate of latex sensitization in health care students starting their exposure to latex gloves. Read More

Int Arch Allergy Immunol 2017 29;172(4):215-223. Epub 2017 Apr 29.

Department of Immunology, University Hospital of Wales, Cardiff, UK.

Background: Allergy is diagnosed from typical symptoms, and tests are performed to incriminate the suspected precipitant. Skin prick tests (SPTs) are commonly performed, inexpensive, and give immediate results. Laboratory tests (ImmunoCAP) for serum allergen-specific IgE antibodies are usually performed more selectively. Read More

Pain Pract 2017 Apr 18. Epub 2017 Apr 18.

Pfizer Inc., New York, New York, U.S.A.

Objective: To compare fibromyalgia (FM) characteristics among patients identified in a community-based chronic pain cohort based on traditional International Classification of Diagnoses 9th revision (ICD-9) diagnostic coding, with that of patients identified using a novel predictive model.

Methods: This retrospective study used data collected from July 1999 to February 17, 2015, in multiple chronic pain clinics in the United States. Patients were assigned to the FM case group based on specific inclusion criteria using ICD-9 codes or, separately, from results of a novel FM predictive model that was developed using random forest and logistic regression techniques. Read More

Physiol Rep 2017 Apr;5(7)

Divers Alert Network, Durham, North Carolina.

A recreational scuba diver wore a second scuba regulator against his face during a scuba dive, attached by an elastic rubber cord necklace. After surfacing, the diver's left face became swollen. Through a process of elimination all other items of scuba equipment were excluded as potential causes. Read More

J Am Coll Health 2017 Mar 31:1-8. Epub 2017 Mar 31.

d Meningitis and Vaccine-Preventable Diseases Branch , Centers for Disease Control and Prevention , Atlanta , Georgia , USA.

Objective: To assess the safety of meningococcal group B (MenB)-4C vaccine.

Participants: Undergraduates, dormitory residents, and persons with high-risk medical conditions received the MenB-4C vaccine two-dose series during mass vaccination clinics from 12/2013 through 11/2014.

Methods: Adverse events (AEs) were identified by 15 minutes of observation postvaccination, spontaneous reports, surveys, and hospital surveillance. Read More

J Dermatolog Treat 2017 Mar 20:1-6. Epub 2017 Mar 20.

b Prosthodontics, Department of Oral Health, College of Medicine, Nursing and Health Sciences , Fiji National University , Suva , Fiji.

Latex allergy (LA) is a commonly observed entity for which sublingual immunotherapy (SLIT) has been shown to be effective in many small randomized clinical trials. The present study was conducted with an aim of systematically reviewing the existing literature on the efficacy and safety of SLIT in patients with LA and to apply the principles of meta-analysis. A search for randomized controlled trials with appropriate search strategy in PubMed and CENTRAL was conducted. Read More

J Allergy Clin Immunol Pract 2017 May - Jun;5(3):873. Epub 2017 Mar 9.

Postgraduate School of Respiratory Medicine, Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy; Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy.

Curr Allergy Asthma Rep 2017 Mar;17(3):14

IPA Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum, Bochum, Germany.

Purpose Of Review: Allergy to natural rubber latex (NRL) reached epidemic proportions during the nineties and led to intense preventive efforts. The aim of this review was to provide a comprehensive compilation of the current status of occupational NRL allergy.

Recent Findings: Recent advances led to the characterization of 15 NRL allergens and the development of assays for measuring the allergen content of NRL materials and specific IgE antibodies against NRL allergen components. Read More

Acta Anaesthesiol Scand 2017 Mar;61(3):281-289

Department of Specialist Allergy and Clinical Immunology, Royal National Throat Nose Ear Hospital, University College London Hospital, London, UK.

Background: Anaphylaxis during general anaesthesia is rare but often severe. Identification of the cause of anaphylaxis and recommendation of a range of drugs or agents likely to be safer for future surgery is a collaborative venture between the allergists and the anaesthesiologists, but it often poses a significant challenge.

Methods: A total of 31 patients who attended the Drug Allergy Unit at University College London Hospital with suspected perioperative anaphylaxis between March 2013 and January 2016 were reviewed retrospectively. Read More

Acta Anaesthesiol Scand 2017 Mar;61(3):290-299

Department of Anaesthesiology and Intensive Care, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.

Background: Immediate hypersensitivity reactions during anaesthesia are rare but potentially life-threatening. The epidemiology changes with time and evolving professional practice, and hence needs to be monitored. Our objective was to follow this epidemiology. Read More

JAMA 2017 01;317(3):309-310

Surgical Outcomes and Quality Improvement Center (SOQIC), Department of Surgery and Center for Healthcare Studies, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

Contact Dermatitis 2017 Apr 28;76(4):195-203. Epub 2016 Dec 28.

Department of Dermatology, Chapel Allerton Hospital, Leeds, LS7 4SA, UK.

Background: Rubber additives constitute an important group of contact allergens, particularly in certain occupations.

Objectives: To collect information regarding the current practice of using a 'rubber series' in Europe, and discuss this against the background of evidence concerning the prevalence of allergy in order to derive a recommendation for a 'European rubber series'.

Methods: The following were performed: (i) a survey targeting all members of the COST action 'StanDerm' consortium, (ii) analysis of rubber contact allergy data in the database of the European Surveillance System on Contact Allergies, and (iii) a literature review. Read More

Eur J Dermatol 2016 Dec;26(6):523-530

Department of Occupational Diseases, Paris University Hospital, Centre Hôtel-Dieu, AP-HP 1, Parvis Notre-Dame, 75004 Paris, France.

Natural rubber latex (NRL) and rubber accelerators are well-known causes of occupational skin diseases. The latest epidemiological data on rubber allergy show that rubber additives are still among the allergens most strongly associated with occupational contact dermatitis, however, a decrease in NRL allergy has been confirmed. A review of recent publications on rubber allergens based on the Pubmed database is presented. Read More

Plast Surg Nurs 2016 Oct/Dec;36(4):173-179

Nancy S. Yunker, BS in Pharmacy, PharmD, FCCP, BCPS, is a board certified pharmacotherapy specialist. She is currently an Assistant Professor of Pharmacy and Nursing at the Virginia Commonwealth University (VCU). Nancy currently practices as an internal medicine pharmacy specialist at the VCU Health System but previously practiced as a general surgery pharmacy specialist at VCU. Bradley J. Wagner, PharmD, BCPS, is a board certified pharmacotherapy specialist. He is currently an internal medicine pharmacy specialist at VCU Health System.

Anaphylaxis occurs in the surgical population and may have devastating consequences. Anaphylaxis and anaphylactoid reactions are immediate hypersensitivity reactions that are most commonly precipitated by medications, insect stings, and foods. In the surgical population, 47. Read More

Yonsei Med J 2017 Jan;58(1):252-254

Department of Internal Medicine, Inje University Haeundae Paik Hospital, Busan, Korea.

Although formaldehyde is well known to cause type 4 hypersensitivity, immunoglobulin E (IgE)-mediated hypersensitivity to formaldehyde is rare. Here, we report a case of recurrent generalized urticaria after endodontic treatment using a para-formaldehyde (PFA)-containing root canal sealant and present a review of previous studies describing cases of immediate hypersensitivity reactions to formaldehyde. A 50-year-old man visited our allergy clinic for recurrent generalized urticaria several hours after endodontic treatment. Read More

Curr Allergy Asthma Rep 2016 Nov;16(11):77

Respiratory Health Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Mailstop HG 900.2, 1095 Willowdale Rd., Morgantown, WV, 26505, USA.

Healthcare workers (HCWs) are exposed to a range of high and low molecular weight agents that are allergic sensitizers or irritants including cleaners and disinfectants, natural rubber latex, and various medications. Studies have shown that exposed HCWs are at risk for work-related rhinitis and asthma (WRA). Work-related rhinitis may precede development of WRA and should be considered as an early marker of WRA. Read More

Clin Cosmet Investig Dermatol 2016 11;9:347-355. Epub 2016 Oct 11.

Department of Dermatology, Loma Linda University, Loma Linda, CA, USA.

Psoriasis is a chronic inflammatory skin disease that has a negative impact on psychosocial well-being and cardiometabolic health. Treatment options for moderate-to-severe psoriasis have expanded with the development of interleukin-17 (IL-17) inhibitors, the first of which is now available - secukinumab. Secukinumab is a fully human monoclonal immunoglobulin G1 κ antibody that selectively inhibits the ligand IL-17A. Read More

Pediatr Allergy Immunol 2017 Feb 23;28(1):38-43. Epub 2016 Nov 23.

Department of Pediatric Allergy and Immunology, School of Medicine, Karadeniz Technical University, Trabzon, Turkey.

Background: Although kiwifruit is known as a common cause of food allergy, population-based studies concerning the prevalence of kiwifruit allergy do not exist. We aimed to determine the prevalence and clinical characteristics of IgE-mediated kiwifruit allergy in 6-18-year-old urban schoolchildren in a region where kiwifruit is widely cultivated.

Methods: This cross-sectional study recruited 20,800 of the randomly selected 6-18-year-old urban schoolchildren from the Rize city in the eastern Black Sea region of Turkey during 2013. Read More

Contact Dermatitis 2016 Oct;75(4):256-7

Department of Periodontology and Oral Implantology, DY Patil University School of Dentistry, 400706, Navi Mumbai, India.

Allergy 2017 Feb 27;72(2):201-206. Epub 2016 Sep 27.

Department of Immunology, Allergology, and Rheumatology Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp University Hospital, Antwerpen, Belgium.

IgE-mediated Cannabis (C. sativa, marihuana) allergy seems to be on the rise. Both active and passive exposure to cannabis allergens may trigger a C. Read More

Anesth Prog Fall 2016;63(3):160-7

Professor and Chair, Department of Dental Anesthesiology, University of Pittsburgh, Pennsylvania.

The incidence of anaphylactic/anaphylactoid reactions has been reported to vary between 1 : 3500 and 1 : 20,000 cases with a mortality rate ranging from 3 to 9%. Clinical signs present as skin rash, urticaria, angioedema, bronchospasm, tachycardia, bradycardia, and hypotension. Rapid identification and treatment are crucial to overall patient prognosis, as delayed intervention is associated with increased mortality. Read More

Hautarzt 2016 Oct;67(10):780-785

Univ. Klinik für Dermatologie, LKH Graz, Auenbruggerplatz 8, 8036, Graz, Österreich.

The oral allergy syndrome is one of the most common form of food allergy and manifests as contact urticaria of the oral mucosa after consumption of cross reacting foods. Whereas allergic contact stomatitis often occurs due to dental materials, allergic contact cheilitis is usually a reaction due to topical therapeutics like herpes ointments or lip care products. As late type reactions are more frequent than immediate type reactions in the anogenital mucosa, contact dermatitis in this area should be identified via epicutaneous testing. Read More

J Investig Allergol Clin Immunol 2016 ;26(4):278

J Investig Allergol Clin Immunol 2016 ;26(4):278

Allergologie, Hôpital Arnaud de Villeneuve.

Adv Exp Med Biol 2016 Jul 29. Epub 2016 Jul 29.

Division of Clinical Occupational Medicine, Institute for Occupational and Maritime Medicine (ZfAM), University Medical Center Hamburg-Eppendorf, 10 Seewartenstraße, 20459, Hamburg, Germany.

The use of natural rubber latex (NRL) gloves in many occupations may lead to latex sensitization, allergic asthma, and skin reactions. Due to their good properties and environmental safety NRL gloves are still being used in the healthcare setting, but also in the food industry, by hairdressers, cleaners, etc. The aim of our study was to assess the protein and NRL allergen content in commercial gloves by different methods, including a new assay. Read More

PLoS One 2016 28;11(7):e0159542. Epub 2016 Jul 28.

School of Life Sciences, University of Nottingham, University Park, Nottingham, NG7 2RD, United Kingdom.

IgG antibodies produced by rabbits immunized against S. mansoni antigens cross-reacted with aqueous soluble constituents of a variety of allergens. The antibody cross-reactivity was largely sensitive to degradation by treatment of the target antigens with sodium meta-periodate, suggesting the cross-reactivity was due to carbohydrate determinants that were common to both the schistosome and the allergens (CCDs). Read More

Contact Dermatitis 2016 Oct 20;75(4):213-22. Epub 2016 Jul 20.

Occupational Dermatology Research and Education Centre, Skin and Cancer Foundation Inc., Carlton, Victoria, 3053, Australia.

Background: Healthcare workers (HCWs) are at risk of developing occupational skin disease (OSD).

Objectives: To ascertain the causes of OSD in Australian HCWs in a tertiary referral clinic.

Methods: A retrospective review was performed of patients assessed at the Occupational Dermatology Clinic in Melbourne from 1993 to 2014. Read More

Am J Infect Control 2016 Dec 4;44(12):1645-1649. Epub 2016 Jul 4.

Institute for Skin Integrity and Infection Prevention, School of Human & Health Sciences, University of Huddersfield, Huddersfield, United Kingdom. Electronic address:

Background: Medical examination gloves and surgical gloves protect the wearer directly and the patient indirectly from the risk of contamination. Because of concerns related to latex allergy, an increasing trend toward the use of synthetic gloves made of materials other than latex is observable. However, currently it is unknown if the physical properties of different materials may influence bacterial passage in case of a glove puncture. Read More

Rev Chil Pediatr 2016 Nov - Dec;87(6):468-473. Epub 2016 Jun 25.

Departamento de Pediatría Sur, Facultad de Medicina, Universidad de Chile, Santiago de Chile, Chile. Electronic address:

Introduction: The prevalence of latex sensitisation varies according to the population studied. There are various risk factors that increase latex sensitisation, such as genetic risk, atopy, and multiple surgeries.

Objective: To characterise patients referred to an Immunology Unit with suspected latex allergy, and to analyse their clinical features and risk factors. Read More

Contact Dermatitis 2016 Oct 28;75(4):223-9. Epub 2016 Jun 28.

Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, 2400 Copenhagen, Denmark.

Background: Occupational contact dermatitis is common in healthcare workers. Although irritant contact dermatitis resulting from wet work is the most frequently reported cause, healthcare workers also constitute high-risk group for the development of allergic contact dermatitis and contact urticaria.

Objectives: To evaluate the prevalence of delayed-type and immediate-type hypersensitivity in 120 healthcare workers with hand eczema. Read More

Postepy Dermatol Alergol 2016 Apr 16;33(2):120-7. Epub 2016 May 16.

Department of Allergology, Medical University of Gdansk, Gdansk, Poland.

Introduction: Differentiating between cross-reactivity and double sensitization is still a challenging issue in allergology.

Aim: To differentiate cross-reactions accompanying latex allergy with the use of the ISAC test.

Material And Methods: Thirty-nine patients reporting immediate allergic reactions to latex were enrolled into the study (group A). Read More

Adv Exp Med Biol 2016;921:37-44

Division of Clinical Occupational Medicine, Institute for Occupational and Maritime Medicine (ZfAM), University Medical Center Hamburg-Eppendorf, 10 Seewartenstraße, 20459, Hamburg, Germany.

The use of natural rubber latex (NRL) gloves in many occupations may lead to latex sensitization, allergic asthma, and skin reactions. Due to their good properties and environmental safety NRL gloves are still being used in the healthcare setting, but also in the food industry, by hairdressers, cleaners, etc. The aim of our study was to assess the protein and NRL allergen content in commercial gloves by different methods, including a new assay. Read More

Presse Med 2016 Sep 12;45(9):758-67. Epub 2016 May 12.

Nouvel Hôpital Civil, hôpitaux universitaires de Strasbourg, service d'anesthésie-réanimation chirurgicale, 1, place de l'Hôpital, BP 426, 67091 Strasbourg cedex, France.

Anaphylactic reactions may be either of immune (allergy, usually IgE-mediated, sometimes IgG-mediated) or non-immune origin. The incidence of anaphylactic reactions during anaesthesia varies between countries ranging from 1/1250 to 1/18,600 per procedure. In France, the estimated incidence of allergic reactions is 100. Read More

Eur Arch Paediatr Dent 2016 Aug 14;17(4):277-81. Epub 2016 May 14.

Our Lady's Children's Hospital Crumlin, Dublin 12, Ireland.

Background: An allergic reaction following a dental procedure is a rare event. A local anaesthetic (LA) may initially be suspected as a causative agent but allergy to dental LA solutions is extremely rare.

Case Report: This report concerns a 13 year old child who underwent dental treatment and was exposed to Lignospan Special(®) LA, mouthwash, latex gloves, ibuprofen medication, and a Magnum(®) (almond) ice cream all within 45 min. Read More