Search Our Scientific Publications & Authors

Food Chem 2019 Jun 25;284:245-253. Epub 2019 Jan 25.

Universidade Federal do Ceará, Departamento de Bioquímica e Biologia Molecular, Fortaleza, Ceará CEP 60.440-970, Brazil. Electronic address:

The present study evaluated four laticifer fluids as a novel source of peptidases capable of hydrolyzing proteins in cow's milk. The latex peptidases from Calotropis procera (CpLP), Cryptostegia grandiflora (CgLP), and Carica papaya (CapLP) were able to perform total hydrolysis of caseins after 30 min at pH 6.5, as confirmed by a significant reduction in the residual antigenicity. Read More

J Patient Saf 2019 Jan 31. Epub 2019 Jan 31.

Edward P. Lawrence Center for Quality and Safety, Massachusetts General Hospital and the Massachusetts General Professional Organization.

Background: The epidemiology of hospital adverse reactions (ARs), particularly allergic reactions, or hypersensitivity reactions (HSRs), is poorly defined. To determine priorities for allergy safety in healthcare, we identified and described safety reports of allergic reactions.

Methods: We searched the safety report database of a large academic medical center from April 2006 to March 2016 using 101 complete, truncated, and/or misspelled key words related to allergic symptoms, treatments, and culprits (e. Read More

Neurogastroenterol Motil 2019 Jan 31:e13552. Epub 2019 Jan 31.

Department of Gastroenterology, Royal North Shore Hospital, University of Sydney, Sydney, New South Wales, Australia.

Background: Anorectal manometry (ARM) and balloon expulsion test (BET) are pivotal in investigation of anorectal disorders. There is controversy, however, about normal values and optimum methodology for performing these tests. Our aims were to compare BET using three different balloons and to establish normal values for ARM and BET in health. Read More

Eur Ann Allergy Clin Immunol 2018 Nov 24;50(6):281-282. Epub 2018 Oct 24.

Ambulatorio di Allergologia, Clinica San Carlo, Paderno Dugnano (MI), Italy.

Rev Alerg Mex 2018 Oct-Dec;65(4):379-388

Secretaría de Salud, Hospital General de México, Servicio Alergia e Inmunología Clínica, Ciudad de México, México.

Background: Perioperative hypersensitivity reactions constitute a global health problem, with an estimated incidence of 1 per 100,000 procedures and a mortality rate of 0.1 to 9 %. Main risk factors are a history of allergy to other drugs, atopy, associated psychiatric disorders and previous surgeries. Read More

Curr Opin Allergy Clin Immunol 2018 Dec 20. Epub 2018 Dec 20.

Department of Occupational Lung Disease, Royal Brompton Hospital, London SW3 6LR.

Purpose Of Review: There is an unmet need for better immunological tests in cases of suspected occupational asthma to many workplace chemicals; here we consider the basophil activation test (BAT), a potential alternative to the detection of specific IgE antibodies.

Recent Findings: BAT is fairly widely used in general allergy services; and there is increasing experience of its use in the diagnosis of occupational allergy to low molecular weight agents and chemicals including wood dusts, persulphates, antibiotics and latex.

Summary: There is potential for BAT to become a useful tool in the clinical consideration of occupational asthma and of its mechanisms, and even to take a place in a Bayesian-based diagnostic algorithm. Read More

Medicine (Baltimore) 2018 Dec;97(51):e13293

Department of Obstetrics and Gynecology, Taipei Veterans General Hospital.

There is an increase in prevalence and financial burden of childhood atopic disorders in recent years. Understanding allergic conditions of pregnant women is important for developing strategies for prevention and management of allergy-related diseases. However, little is currently known about the atopic conditions in pregnant women. Read More

Paediatr Anaesth 2019 Feb 19;29(2):153-160. Epub 2018 Dec 19.

Department of Anaesthesia and Pain Management, Perth Children's Hospital, Perth, Australia.

Background And Aim: Pediatric patients increasingly report allergies, including allergies to food and medications. We sought to determine the incidence and, nature of parent-reported allergies in children presenting for surgery and its significance for anesthetists.

Methods: We prospectively collected data on admissions through our surgical admission unit over a 2-month period at a pediatric tertiary care teaching hospital. Read More

Pediatr Transplant 2019 02 4;23(1):e13316. Epub 2018 Nov 4.

Division of Pediatric Cardiology, Department of Pediatrics, Stanford University Medical Center, Palo Alto, California.

Background: Pediatric heart transplant (PedHtx) patients have increased cardiovascular risk profiles that affect their long-term outcomes and quality of life. We designed a 12- to 16-week diet and exercise intervention delivered via live video conferencing to improve cardiovascular health. Our methodology and baseline assessment of the first 13 enrolled patients are reported. Read More

Open Access Maced J Med Sci 2018 Sep 23;6(9):1722-1726. Epub 2018 Sep 23.

College of Dentistry, Jazan University, Jazan, Saudi Arabia.

Aim: The present study was aimed to assess the level of awareness and occupational hazards of dental students and professionals who are working at dental college and hospital, Jazan University, Saudi Arabia.

Material And Methods: Data has been collected through a self-administrated questionnaire with closed questions. The questionnaire consisted of questions on personal information like age, gender, years of experience and awareness of occupational hazards, seminar attendance, safety measures practised, and experience of occupational hazard while in practice. Read More

J Med Invest 2018 ;65(3.4):292-295

Department of Pediatrics, Tokushima University.

Natural rubber latex (NRL) allergy is one of the most important causes of severe anaphylaxis during medical intervention. We report a pediatric case of latex allergy with multiple surgical histories. A 12-year-old girl developed anaphylactic shock during the pyeloplasty for ureteropelvic junction restenosis. Read More

J Allergy Clin Immunol Pract 2018 Nov - Dec;6(6):1877-1878. Epub 2018 Sep 21.

Division of Allergy/Immunology/Rheumatology, Department of Pediatrics, University of North Carolina-Chapel Hill, Chapel Hill, NC. Electronic address:

Reduction in the prevalence of IgE-mediated allergy to latex proteins from gloves in patients may lead to lax attention by health care personnel to avoid use of latex products in latex-allergic subjects. Recent evidence from the Pennsylvania Patient Safety Reporting System shows an alarming continuation of adverse events mostly from latex urinary catheters. We are strongly advocating that health care personnel must continue to pay close attention to avoidance of latex in patients with a history of latex allergy. Read More

Front Pediatr 2018 7;6:236. Epub 2018 Sep 7.

Department of Research and Diagnostics, Istituto G. Gaslini, Genoa, Italy.

During general anesthesia, while muscle relaxants, latex and antibiotics are normally considered as very common causes of anaphylactic reactions, there are no documented cases of anaphylaxis due to inhalational agents. We report the case of a 6-year-old child scheduled for adenotonsillectomy who had an anaphylactic shock reaction due to Sevoflurane. Several allergic tests were performed to detect the trigger. Read More

Mol Immunol 2018 Nov 19;103:89-95. Epub 2018 Sep 19.

Institute of Biosciences and BioResources, CNR, I-80131 Naples, Italy. Electronic address:

Allergy to pomegranate is often associated with severe symptoms. Two allergens have previously been described: 9k-LTP Pun g 1 and pommaclein Pun g 7. This study describes the isolation of a chitinase III, identified by direct protein sequencing and mass spectrometry. Read More

Cutis 2018 Aug;102(2):116-118

Department of Dermatology, Loma Linda University, California, USA.

An allergic reaction provoked by reexposure to an allergen or antigen is known as a type I or immediate hypersensitivity reaction. Latex allergy is a common cause of type I hypersensitivity reactions. Allergic responses to latex in psoriasis patients receiving frequent injections with biologic agents are not commonly reported in the literature. Read More

Int Arch Allergy Immunol 2019 13;178(1):83-88. Epub 2018 Sep 13.

Department of Dermatology, Venereology, and Allergology, University Medical Center, Georg August University, Göttingen,

Background: Natural rubber latex (NRL) allergy is commonly diagnosed according to medical history, skin allergy tests, and serological analyses. However, skin tests are increasingly being abandoned because of (i) their time-consuming nature, (ii) latex preparations for skin tests being not commercially available, and (iii) the use of in-house prepared test solutions is becoming ever more difficult due to increasing regulatory hurdles. In this light, we have evaluated differences in the profiles of current and former patients with suspected latex allergy. Read More

Int J Food Microbiol 2019 Jan 28;289:7-16. Epub 2018 Aug 28.

Laboratorio de Bioquímica y Biología Molecular, Departamento de Biología, Universidad de La Serena, La Serena, Chile; Millennium Nucleus for Fungal Integrative and Synthetic Biology (FISB), Chile. Electronic address:

The aim of this study was to determine the antifungal activity of the proteolytic fraction P1G10 from Vasconcellea cundinamarcencis (ex-Carica candamarcensis) against Botrytis cinerea, the causative agent of pre- and postharvest damaging disease in fruit and vegetables. The survival of B. cinerea at different concentrations of P1G10 showed that 1 mg/mL inhibited 50% of mycelium growth after 72 h incubation. Read More

J Allergy Clin Immunol Pract 2018 Nov - Dec;6(6):1813-1823. Epub 2018 Aug 29.

Faculty of Medicine and Health Science, Department of Immunology, Allergology, Rheumatology, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium. Electronic address:

Secondary food allergies due to cross-reactivity between inhalant and food allergens are a significant and increasing global health issue. Cross-reactive food allergies predominantly involve plant-derived foods resulting from a prior sensitization to cross-reactive components present in pollen (grass, tree, weeds) and natural rubber latex. Also, primary sensitization to allergens present in fungi, insects, and both nonmammalian and mammalian meat might induce cross-reactive food allergic syndromes. Read More

J Investig Allergol Clin Immunol 2018 Aug;28(4):269-271

Department of Biomedical Sciences and Human Oncology Unit of Internal Medicine "G. Baccelli" 8, "Aldo Moro" University of Bari Medical School, Policlinico, Bari, Italy.

Clin Mol Allergy 2018 9;16:16. Epub 2018 Jul 9.

2Department of Emergency and Organ Transplantation, School and Chair of Allergology and Clinical Immunology, University of Bari-Aldo Moro, Bari, Italy.

Adverse reactions (ARs) to drugs administered during general anesthesia may be very severe and life-threatening, with a mortality rate ranging from 3 to 9%. The adverse reactions to drugs may be IgE and non-IgE-mediated. Neuromuscular blocking agents (NMBA) represent the first cause of perioperative reactions during general anesthesia followed by latex, antibiotics, hypnotic agents, opioids, colloids, dyes and antiseptics (chlorhexidine). Read More

Rev Alerg Mex 2018 Apr-Jun;65(2):128-139

Instituto Mexicano del Seguro Social, Hospital General de Zona 30, Mexicali, Baja California, México.

Background: The prevalence of latex allergy ranges from 0.8 to 6.5% and is the second cause of perioperative anaphylaxis. Read More

Int Arch Allergy Immunol 2018;177(3):238-244. Epub 2018 Jul 5.

Clinical Department of Dermatovenereology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.

Background: Dental workers often experience unwanted allergic and nonallergic skin reactions resulting in different contact dermatoses (e.g., contact urticaria, irritant and allergic contact dermatitis) that are often attributed to rubber gloves. Read More

Br J Anaesth 2018 Jul 21;121(1):159-171. Epub 2018 May 21.

Medicines and Healthcare products Regulatory Agency, London, UK.

Background: Anaphylaxis during anaesthesia is a serious complication for patients and anaesthetists.

Methods: The 6th National Audit Project (NAP6) on perioperative anaphylaxis collected and reviewed 266 reports of Grades 3-5 anaphylaxis over 1 yr from all NHS hospitals in the UK.

Results: The estimated incidence was ≈1:10 000 anaesthetics. Read More

Br J Anaesth 2018 Jul 21;121(1):146-158. Epub 2018 May 21.

Manchester University NHS Foundation Trust, Manchester, UK; Manchester Academic Heath Science Centre, University of Manchester, Manchester, UK; Royal College of Anaesthetists, London, UK.

Background: Details of the current UK drug and allergen exposure were needed for interpretation of reports of perioperative anaphylaxis to the 6th National Audit Project (NAP6).

Methods: We performed a cross-sectional survey of 356 NHS hospitals determining anaesthetic drug usage in October 2016. All cases cared for by an anaesthetist were included. Read More

Sao Paulo Med J 2018 Jun 11. Epub 2018 Jun 11.

MD, PhD. Attending Physician, Clinical Immunology and Allergy Division, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo (SP), Brazil.

Context: Adverse reactions associated with prick tests are rare but may be present as serious systemic reactions.

Case Report: A 38-year-old female nursing technician complained of three episodes of anaphylaxis in one year, all in the workplace. To investigate latex allergy, the patient underwent the prick test with latex, and immediately developed a rash, itchy skin, hoarseness, dyspnea and dry cough. Read More

J Allergy Clin Immunol Pract 2019 Jan 23;7(1):300-302. Epub 2018 May 23.

Department of Emergency and Organ Transplantation, School of Allergology and Clinical Immunology, University of Bari Aldo Moro, Bari, Italy. Electronic address:

J Oncol Pharm Pract 2018 Jan 1:1078155218775473. Epub 2018 Jan 1.

7 Unidad de Reumatología. UGC Cirugía Ortopédica, Traumatología y Reumatología, Hospital Universitario Puerta del Mar, Cádiz, Spain.

We describe a successful desensitization to alemtuzumab in one patient diagnosed with T-cell prolymphocytic leukaemia. Alemtuzumab treatment was initiated during infusion number 18, the patient showed cutaneous eruption with a miliary pattern, despite premedication with corticosteroids and antihistamines. The eruption returned with successive alemtuzumab infusions (infusions 19, 20 and 21), remained present for longer and was more severe with each infusion. Read More

Clin Exp Allergy 2018 Jul 19;48(7):846-861. Epub 2018 Jun 19.

Manchester University NHS Foundation Trust, Manchester, UK.

Background: The Royal College of Anaesthetists 6th National Audit Project examined Grade 3-5 perioperative anaphylaxis for 1 year in the UK.

Objective: To describe the causes and investigation of anaphylaxis in the NAP6 cohort, in relation to published guidance and previous baseline survey results.

Methods: We used a secure registry to gather details of Grade 3-5 perioperative anaphylaxis. Read More

BMC Pregnancy Childbirth 2018 May 15;18(1):168. Epub 2018 May 15.

Division of Global Health and Human Rights, Department of Emergency Medicine, Massachusetts General Hospital, 125 Nashua St, Suite 910, Boston, MA, 02114, USA.

Background: Postpartum hemorrhage is the leading cause of maternal mortality in low- and middle-income countries. While evidence on uterine balloon tamponade efficacy for severe hemorrhage is encouraging, little is known about safety of this intervention. The objective of this study was to evaluate the safety of an ultra-low-cost uterine balloon tamponade package (named ESM-UBT) for facility-based management of uncontrolled postpartum hemorrhage (PPH) in Kenya and Sierra Leone. Read More

Dermatitis 2018 May/Jun;29(3):176

Postepy Dermatol Alergol 2018 Apr 24;35(2):145-150. Epub 2018 Apr 24.

Allergy Unit, Università Cattolica del Sacro Cuore - Fondazione Policlinico "A. Gemelli", Rome, Italy.

Introduction: The only etiological and decisive therapy, able to influence the natural history of latex allergy is the specific desensitization.

Aim: To verify the clinical efficacy and immunological changes determined by latex sublingual immunotherapy in allergic patients who underwent this treatment for at least 3 years.

Material And Methods: We enrolled 76 patients (16 males and 60 females, mean age 34 years old) with evidence of a natural rubber latex allergy. Read More

Rev Alerg Mex 2018 Jan-Mar;65(1):10-18

Hospital Civil de Guadalajara "Dr. Juan I. Menchaca", Servicio de Alergia e Inmunología Clínica, Guadalajara, Jalisco, México.

Background: Prevalence of latex allergy in medical students is not known.

Objective: To determine the prevalence of self-reported latex allergy and associated factors in medical students.

Methods: Cross-sectional, analytical study of students with or without self-reported latex allergy. Read More

Rev Alerg Mex 2018 Jan-Mar;65(1):3-9

Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades, Servicio de Alergia e Inmunología Clínica. Ciudad de México, México.

Background: Latex-fruit syndrome (LFS) is characterized by allergy to latex and plants. Papain, chymopapain, caricaine and class I chitinases are papaya's most allergenic proteins. The similarity between latex hevein epitopes and papaya class I chitinases might explain the latex-papaya syndrome (LPS). Read More

Mol Immunol 2018 Aug 9;100:21-27. Epub 2018 Apr 9.

Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA), Bochum, Germany. Electronic address:

We are now in the epoch of "molecular allergology" and numerous clinically relevant allergenic molecules are available improving the performance of in vitro allergen tests and allergen detection methods. This review is focusing on characterized occupational allergens and their implementation into the in vitro diagnosis for occupational allergy and in allergen detection methods. More than 400 occupational agents are identified and documented as being 'respiratory sensitizers', but currently only a limited number of them are characterized on the molecular level and available for routine diagnosis as native or recombinant allergens. Read More

Curr Opin Allergy Clin Immunol 2018 06;18(3):168-176

Department of Philosophical, Methodological and Experimental Disciplines, University of Guadalajara, Guadalajara, Mexico.

Purpose Of Review: Allergen immunotherapy (AIT) is a well recognized and extensively studied therapeutic intervention for some allergic diseases. Every year new systematic reviews and meta-analysis provide the most powerful source of evidence to orient decision making on prevention or efficacy of AIT. We here discuss systematic reviews and meta-analyses on AIT (published January 2017 to February 2018). Read More

Int Arch Allergy Immunol 2018 28;176(1):1-7. Epub 2018 Mar 28.

Division of Allergy and Immunology, Department of Internal Medicine, Faculty of Medicine, Ege University, Izmir, Turkey.

Background: It has been suggested that latex-specific IgE analysis may lead to false-positive results, especially in patients with pollen allergy. In the present study, the reasons underlying clinically irrelevant latex-specific IgE positivity were investigated.

Methods: Thirty patients with latex allergy (group 1), 89 patients sensitised to aeroallergens (group 2a), and 98 healthy individuals without allergy (group 2b) were enrolled. Read More

Food Chem Toxicol 2018 May 24;115:365-374. Epub 2018 Mar 24.

Razi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran. Electronic address:

Plant-derived foods are the most common allergenic sources in adulthood. Owing to the rapidly increasing prevalence of plant food allergies in industrialized countries, the environmental factors are suspected to play a key role in development of allergic sensitization. The present article provides an overview of ways by which chemicals may influence the development and severity of allergic reactions to plant foods, with especial focus on plant allergens up-regulated under chemical stress. Read More

J Biol Regul Homeost Agents 2018 Jan-Feb;32(1 Suppl. 1):25-28

Departmental Unit of Allergology, Guglielmo da Saliceto Hospital, Piacenza, Italy.

The introduction of highly purified natural and recombinant single allergenic molecules represented an important improvement in the diagnosis of IgE sensitization. The identification of specific IgE against cross-reacting molecules such as profilin, lipid transfer proteins, calcium binding proteins or against “genuine molecules”, represents an added value and allows to distinguish between true and false polysensitization. In vitro tests add information to recognize patients with sensitization to genuine molecules that cause allergic diseases and to evaluate in childhood the spreading of sensitization for each molecule in order to choose the best treatment and to identify the ideal patient for allergen immunotherapy. Read More

J Biol Regul Homeost Agents 2018 Jan-Feb;32(1 Suppl. 1):19-24

Department of Sense Organs, Sapienza University, Rome, Italy.

The skin prick test (SPT) is the most common test for the diagnosis of allergy. SPT is performed by pricking the skin, usually in the volar surface of the forearm, with a lancet through a drop of an allergen extract and is usually the first choice test in the diagnostic workup for allergic diseases because of its reliability, safety, convenience and low cost. SPT is minimally invasive and has the advantage of testing multiple allergens in 15 to 20 min. Read More

Eur Ann Allergy Clin Immunol 2019 Jan 28;51(1):15-20. Epub 2018 Feb 28.

Centro de Investigación en Ciencias Médicas, Universidad Autónoma del Estado de México, Toluca de Lerdo, México.

Summary: Oral allergy syndrome (OAS) is the most common food allergy manifestation amongst adults. However, population studies aimed at estimating its prevalence and associated factors are scarce in Mexi-co. To establish the prevalence of OAS in a sample of university students and to describe their clinical characteristics and its associated factors. Read More

Spec Care Dentist 2018 Mar 7;38(2):89-94. Epub 2018 Mar 7.

Professor, Department of Pediatric Clinic, Preventive and Community Dentistry, Ribeirão Preto Dental School, University of São Paulo, Ribeirão Preto, SP, Brazil.

Myelomeningocele (MMC) is a congenital malformation that occurs in the embryonic period, characterized by failure in closure of the caudal portion of the neural tube during central nervous system formation. Alterations and complications can be associated with this condition, such as hydrocephalus, neurogenic bladder, orthopedic problems, and motor and cognitive impairment. This patients with MMC also have predisposition to develop latex allergy and high caries risk and activity due to deficient oral hygiene, fermentable carbon hydrate-rich diet and prolonged use of sugar-containing oral medications. Read More

Eur Ann Allergy Clin Immunol 2018 May 15;50(3):135-138. Epub 2018 Jan 15.

Division of Allergy, Clinical Immunology and Rheumatology, Department of Pediatrics, Escola Paulista de Medicina-Federal University of São Paulo, São Paulo, Brazil.

Summary: Microarray technique employing molecular allergens is pointed out as a new method to evaluate allergic patients. To evaluate if microarray technique (ImmunoCAP-ISAC®; I-ISAC®) is similar to fluorescence enzyme immunoassay (FEIA; ImmunoCAP®) in the diagnosis of latex allergy (specific IgE to latex plus symptoms) and latex sensitization (only antibody) in pediatric (9-mo to 14-yrs) patients with myelomeningocele undergone to surgical repair. Patients underwent skin prick testing (SPT) to latex and food (prick to prick), and dosage of serum specific IgE to latex and recombinant latex allergens (rHev b 1, rHev b 3, rHev b 5, rHev b 6. Read More

J Investig Allergol Clin Immunol 2018 ;28(1):37-41

Decanato, Facultad de Medicina, Facultad de Medicina, Universidad CEU San Pablo, Grupo Hospitales HM, Spain.

Background And Objective: The increasing prevalence of food allergy affects both patients and their families. Objective: The aim of this study was to evaluate the impact of an online educational program designed for parents and caregivers of children with food allergies. The program was developed by a multidisciplinary group comprising health care professionals, researchers, and expert patients under the participatory medicine model. Read More

J Allergy Clin Immunol Pract 2018 Jul - Aug;6(4):1176-1184. Epub 2018 Feb 14.

Faculty of Medicine and Health Science, Department of Immunology - Allergology - Rheumatology, University of Antwerp, Antwerp University Hospital, Antwerp, Belgium.

Quantification of specific IgE (sIgE) antibodies constitutes an important measure to document anesthesia-related immediate hypersensitivity reactions (IHRs). However, only a few drug-specific assays are available and their predictive value is not known. In cases of non-IgE mediated IHRs, diagnosis might benefit from cellular tests such as basophil mediator release tests and basophil activation tests (BATs). Read More

Curr Allergy Asthma Rep 2018 02 14;18(1). Epub 2018 Feb 14.

Centre Hospitalier Universitaire UCL Namur, Department of Chest Medicine, Université Catholique de Louvain, Yvoir, Belgium.

Purpose Of Review: Numerous clinically relevant allergenic molecules enhance the performance of specific (s) IgE tests and improve the specificity of allergy diagnosis. This review aimed to summarize our current knowledge of the high-molecular-weight allergens involved in the development of occupational asthma and rhinitis and to critically analyze the contribution of component-resolved diagnosis in the management of these conditions.

Recent Findings: There is a lack of standardization and validation for most available extracts of occupational agents, and assessment of sIgE reactivity to occupational allergen components has been poorly investigated, with the notable exception of natural rubber latex (NRL) and wheat flour. Read More

Can J Ophthalmol 2018 02;53(1):29-33

Maisonneuve-Rosemont Hospital, Montreal, Que.

Objective: To evaluate the effectiveness of a topical silicone gel on scars in patients who had undergone bilateral direct brow lift surgery.

Design: A randomized double-blind clinical trial with a placebo applied to one scar and topical silicone gel (Dermatix Ultra; Valeant Pharmaceuticals, Laval, Que.) used on the other scar for 2 months. Read More

Eur Ann Allergy Clin Immunol 2018 Mar 20;50(2):89-91. Epub 2017 Nov 20.

Serviço de Imunoalergologia, Hospital de Dona Estefânia, Centro Hospitalar de Lisboa Central, Lisbon, Portugal; CEDOC, Faculdade de Ciências Médicas (FCM), Universidade Nova de Lisboa, Lisbon, Portugal.

Summary: Piperacillin is a beta-lactam antibiotic of penicillin family. Some penicillins were report-ed as occupational diseases cause, but piperacillin anaphylaxis with occupational sensi-tization is rare. We describe the case of a female nurse with recurrent anaphylaxis in last few months without apparent cause, only in work environment. Read More

J Urol 2017 Aug 15;198(2):244. Epub 2017 May 15.

Contact Dermatitis 2018 Feb;78(2):168-169

Department of Dermatology and Venereology, University Hospital Centre Zagreb, School of Medicine, University of Zagreb, 10000, Zagreb, Croatia.

Clin Infect Dis 2017 Dec;66(suppl_1):S65-S72

Division of Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York.

Background: Naturally occurring botulism is rare, but a large number of cases could result from unintentional or intentional contamination of a commercial food. Despeciated, equine-derived, heptavalent botulinum antitoxin (HBAT) is licensed in the United States. Timely treatment reduces morbidity and mortality, but concerns that botulinum antitoxin can induce anaphylaxis exist. Read More