279,396 results match your criteria Lateral Epicondylitis


Oral Verruciform Xanthoma of lateral border of tongue - a sheep in wolf's clothing".

J Stomatol Oral Maxillofac Surg 2018 Dec 14. Epub 2018 Dec 14.

Assistant Professor, OMS Department, College of Dentistry, King Khalid University, Abha, KSA.

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December 2018

The Medial Pillar Island Flap for Oncoplastic Breast Reconstruction of Upper Pole Defects.

Ann Plast Surg 2018 Dec 13. Epub 2018 Dec 13.

Surgical Oncology, Department of Surgery, University of Massachusetts Medical School, Worcester, MA.

Background: Breast deformity is common following lumpectomy. Use of ptotic lower pole tissue for restoration of volume in the upper pole is quite appealing since it allows for a concomitant lift. This study presents the medial pillar island flap technique of oncoplastic breast reconstruction of upper pole defects. Read More

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December 2018

Tooth development and replacement in the Atlantic Cutlassfish, Trichiurus lepturus, with comparisons to other Scombroidei.

J Morphol 2019 Jan;280(1):78-94

Department of Ecology and Evolutionary Biology and Cornell University Museum of Vertebrates, Cornell University, Ithaca, New York.

Atlantic Cutlassfish, Trichiurus lepturus, have large, barbed, premaxillary and dentary fangs, and sharp dagger-shaped teeth in their oral jaws. Functional teeth firmly ankylose to the dentigerous bones. We used dry skeletons, histology, SEM, and micro-CT scanning to study 92 specimens of T. Read More

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January 2019

Drilling in the dorid species Vayssierea cf. elegans (Gastropoda: Nudibranchia): Functional and comparative morphological aspects.

J Morphol 2019 Jan;280(1):119-132

Invertebrate Zoology Department, Biological Faculty, M.V. Lomonosov Moscow State University, Moscow, Russia.

The drilling mode of feeding is known from two clades of Gastropoda: Caenogastropoda and Heterobranchia. However, the level of convergence and parallelism or homology among these two lineages is unclear. The morphology of the buccal complex is well studied for drilling caenogastropods, but poorly known for drilling nudibranchs. Read More

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January 2019

The application of high frequency ultrasound in the muscles, bones and the thoracodorsal artery in subscapular region and analysis of ultrasonic characteristics.

Eur Rev Med Pharmacol Sci 2018 Dec;22(23):8098-8103

Ultrasonic Department, The Third Hospital of Xi'an, Xi'an, Shaanxi, China.

Objective: To analyze the application value of high-frequency ultrasound in the muscles, bones and the thoracodorsal artery in the subscapular region and summarize the characteristics of ultrasound.

Patients And Methods: Subscapularis muscle, bone and thoracodorsal artery of 72 healthy subjects were examined using high-frequency ultrasound, the initial segment diameter of the thoracodorsal artery and peak systolic blood flow velocity were recorded, and the ultrasonographic characteristics of subscapularis muscle, bone and thoracodorsal artery were summarized.

Results: The spinous processes of 7th thoracic vertebrae, 9th thoracic vertebrae and 11th thoracic vertebrae all showed strong echoes with posterior acoustic shadow. Read More

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December 2018

Histological and clinical outcomes of lateral sinus floor elevation with simultaneous removal of a maxillary sinus pseudocyst.

Authors:
Huajie Yu Lixin Qiu

Clin Implant Dent Relat Res 2018 Dec 17. Epub 2018 Dec 17.

Peking University Hospital of Stomatology Fourth Division, Beijing, China.

Background: Maxillary sinus pathologies are a potential risk for failure of implant and bone augmentation. Management of lateral sinus floor elevation in the presence of a pseudocyst remains controversial, and reports on histological outcomes of endo-sinus bone augmentation with maxillary cysts are scarce.

Purpose: To present a modified surgical technique for removal of maxillary pseudocyst with simultaneous sinus floor elevation, and to evaluate clinical and histological outcomes of the bone grafting. Read More

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December 2018

The potential clinical relevance of anatomical structures and variations of the maxillary sinus for planned sinus floor elevation procedures: A retrospective cone beam computed tomography study.

Clin Implant Dent Relat Res 2018 Dec 17. Epub 2018 Dec 17.

Department of Otorhinolaryngology, Atatürk State Hospital, Antalya, Turkey.

Background: Complications arising from sinus floor elevation (SFE) with lateral approach surgery can be avoided by means of maxillary sinus examination in the preoperative period.

Purpose: To investigate anatomical variations in the maxillary sinus by making use of cone beam computed tomography (CBCT) in terms of SFE with a lateral approach.

Materials And Methods: Two hundred twenty eight maxillary sinuses in 114 patients were included. Read More

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December 2018

Improving the rates of Aspergillus detection: an update on current diagnostic strategies.

Expert Rev Anti Infect Ther 2018 Dec 17:1-12. Epub 2018 Dec 17.

d Division of Infectious Diseases, Department of Medicine , University of California-San Diego , San Diego , CA , USA.

Introduction: The spectrum of disease caused by Aspergillus spp. is dependent on the immune system of the host, and ranges from invasive aspergillosis (IA) to chronic pulmonary aspergillosis (CPA). Early and reliable diagnosis of Aspergillus disease is important to decrease associated morbidity and mortality. Read More

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December 2018

Chemicals, somatic mutations and neurodegeneration: Evidence from Western Pacific ALS-PDC.

Neuropathol Appl Neurobiol 2018 Dec 17. Epub 2018 Dec 17.

Department of Neurology, School of Medicine and Oregon Institute of Occupational Health Sciences, Oregon Health & Science University, Portland, Oregon, USA.

Leija-Salazar and colleagues discuss current evidence for somatic mutations in neurodegeneration, focusing on sporadic, usually late-onset neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Parkinson disease (PD) and Alzheimer's disease (AD). Somatic mutation, defined as any acquired post-zygotic change in the nuclear genome, has long been linked to chemically induced DNA damage, aging and cancer but little more than a theoretical basis exists to associate comparable phenomena with sporadic neurodegenerative diseases. Whereas specific exogenous mutagenic chemicals, such as the fungal toxin aflatoxin B1, the amine dye benzo(a)-pyrene, and a tobacco-specific N-nitrosamine, are key examples of proven mutagenic carcinogens [2], only broad exposure categories, such as tobacco smoke, have been linked positively with ALS and AD, and negatively with PD. Read More

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December 2018

New molecular diagnostic trends and biomarkers for Amyotrophic Lateral Sclerosis.

Hum Mutat 2018 Dec 17. Epub 2018 Dec 17.

Department of Pharmacy, School of Health Sciences, University of Patras, Rion GR-265 04, Patras, Greece.

Amyotrophic lateral sclerosis (ALS) is a rare and fatal neurodegenerative disorder. Two forms are recognized, familial (FALS) that accounts for 5-10% of ALS cases, and sporadic (SALS) that accounts for the rest. Early diagnosis of ALS is important since it improves their therapeutic efficacy. Read More

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December 2018

A High Current Density Direct-Current Generator Based on a Moving van der Waals Schottky Diode.

Adv Mater 2018 Dec 17:e1804398. Epub 2018 Dec 17.

College of microelectronics, College of Information Science and Electronic Engineering, Zhejiang University, Hangzhou, 310027, P. R. China.

Traditionally, Schottky diodes are used statically in the electronic information industry while dynamic or moving Schottky diode-based applications are rarely explored. Herein, a novel Schottky diode named "moving Schottky diode generator" is designed, which can convert mechanical energy into electrical energy by means of lateral movement between the graphene/metal film and semiconductor. The mechanism is based on the built-in electric field separation of the diffusing carriers in moving Schottky diode. Read More

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December 2018

Rapid Detection of Severe Fever with Thrombocytopenia Syndrome Virus via Colloidal Gold Immunochromatography Assay.

ACS Omega 2018 Nov 13;3(11):15399-15406. Epub 2018 Nov 13.

Jiangsu Province Hi-Tech Key Laboratory for Bio-Medical Research, School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, China.

To develop the point-of-care testing method to facilitate the clinical detection of severe fever with thrombocytopenia syndrome virus (SFTSV), colloidal gold paper-based lateral flow immunochromatography test strips (LFITSs) have been fabricated for the rapid detection for the first time. The pH value and the amount of monoclonal antibody to prepare colloidal gold nanoparticle-labeled monoclonal antibody bioconjugates were optimized. In addition, 0. Read More

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November 2018

Competitive Association of Antibiotics with a Clay Mineral and Organoclay Derivatives as a Control of Their Lifetimes in the Environment.

ACS Omega 2018 Nov 12;3(11):15332-15342. Epub 2018 Nov 12.

Institut des Sciences de la Terre d'Orléans, UMR 7327, CNRS-Université d'Orléans, 1A Rue de la Férollerie, 45071 Orléans Cedex 2, France.

A Na-smectite clay mineral (Na-Mt) was exchanged with two concentrations of benzyldimethyltetradecyl ammonium chloride cationic surfactant up to one time the cation exchange capacity. Nonionic organoclay was prepared with polyoxyethylene (20) oleyl ether (Brij-O20) nonionic surfactant at one concentration. The resulting organoclays displayed lateral layer organization of the surfactants within their interlayer space. Read More

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November 2018

Total necrosis of cornea, iris and crystalline lens with exposure of vitreous hyaloid face in the context of recalcitrant acanthamoeba keratitis.

J Curr Ophthalmol 2018 Dec 19;30(4):377-380. Epub 2018 Mar 19.

Department of Optometry, School of Rehabilitation, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Purpose: To report a rare and complicated case of acanthamoeba keratitis (AK) presented with total necrosis and dislodgment of cornea, iris, and crystalline lens with exposure of vitreous hyaloids face.

Methods: Case report of 28-year-old female referred to the Farabi Eye Hospital with a history of known left eye AK since 4 months earlier. She also had a history of soft contact lens wear for two years and topical steroid use before proper diagnosis. Read More

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December 2018

Misdiagnosis: Hypoglossal palsy mimicking bulbar onset amyotrophic lateral sclerosis.

eNeurologicalSci 2019 Mar 22;14:6-8. Epub 2018 Nov 22.

Mayo Clinic Florida, Department of Neurology, USA.

Bulbar onset amyotrophic lateral sclerosis (bALS) is a currently incurable neurodegenerative condition characterized by insidious progression of bulbar muscle paresis; namely dyspnea, dysarthria, and dysphagia. The diagnosis of bALS requires exclusion of mimicking pathologies as the diagnosis of bALS may have significant implications on patients' quality of life, future planning, and familial/social dynamics. Herein we present two cases which were misdiagnosed as bALS when in fact a structural lesion of the hypoglossal nerve was causative. Read More

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Dataset on the dynamic structural parameters of an old existing building exposed to earthquake loading before and after strengthening techniques - A case study, Lebanon.

Data Brief 2018 Dec 20;21:2262-2283. Epub 2018 Nov 20.

School of Civil Engineering, Universiti Sains Malaysia, Engineering Campus, 14300 Nibong Tebal, Penang, Malaysia.

This paper provides data and information on Beirut Arab University׳s existing old building in Lebanon. The building was primarily designed to resist gravity loads only, with no attention to seismic or lateral load effects. The data shows that there is a need to improve the conditions of the existing old building by applying new features that function as seismic capacity resistance. Read More

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December 2018

Functional Assessment of an Overexpressed Arabidopsis Purple Acid Phosphatase Gene () in Tobacco Plants.

Iran J Biotechnol 2018 Apr 18;16(1):e2024. Epub 2018 Apr 18.

Department of Agronomy and Plant Breeding, Faculty of Agriculture, Tabriz University, 5166616471, Tabriz, Iran.

Background: Overexpression of known genes encoding key phosphate (Pi)-metabolizing enzymes, such as acid phosphatases (APases), is presumed to help plants with Pi availability and absorption as they are mostly exposed to suboptimal environmental conditions for this vital element.

Objectives: In this study, the overexpression effect of , one of the main contributors in retrieving Pi from intracellular and extracellular compounds, was evaluated from various viewes in tobacco plant.

Materials And Methods: As a heterologous expression system, the encoding cDNA sequence of AtPAP26 was transferred into tobacco plants. Read More

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April 2018
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Changes in Serine Racemase-Dependent Modulation of NMDA Receptor: Impact on Physiological and Pathological Brain Aging.

Front Mol Biosci 2018 28;5:106. Epub 2018 Nov 28.

UNICAEN, INSERM, COMETE, Normandie University, Caen, France.

The N-methyl-D-Aspartate glutamate receptors (NMDARs) are pivotal for the functional and morphological plasticity that are required in neuronal networks for efficient brain activities and notably for cognitive-related abilities. Because NMDARs are heterogeneous in subunit composition and associated with multiple functional regulatory sites, their efficacy is under the tonic influence of numerous allosteric modulations, whose dysfunction generally represents the first step generating pathological states. Among the enzymatic candidates, serine racemase (SR) has recently gathered an increasing interest considering that it tightly regulates the production of d-serine, an amino acid now viewed as the main endogenous co-agonist necessary for NMDAR activation. Read More

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November 2018

Raster-scan optoacoustic angiography of blood vessel development in colon cancer models.

Photoacoustics 2019 Mar 23;13:25-32. Epub 2018 Nov 23.

Institute of Applied Physics, Russian Academy of Sciences, 46 Ulyanov Str., Nizhny Novgorod 603950, Russia.

Raster-scan optoacoustic angiography at 532 nm wavelength with 50 μm lateral resolution at 2 mm diagnostic depth was used for quantitative characterization of neoangiogenesis in colon cancer models. Two tumor models of human colon adenocarcinoma (HT-29) and murine colon carcinoma (CT26) different in their histology and vascularization were compared. Tumors of both origins showed an inhomogeneous distribution of areas with high and low vascularization. Read More

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Phenotypic heterogeneity of astrocytes in motor neuron disease.

Clin Exp Neuroimmunol 2018 Nov 4;9(4):225-234. Epub 2018 Oct 4.

Department of Neuroscience and Pathobiology Research Institute of Environmental Medicine Nagoya University Nagoya Japan.

Accumulating evidence has shown that astrocytes do not just support the function of neurons, but play key roles in maintaining the brain environment in health and disease. Contrary to the traditional understanding of astrocytes as static cells, reactive astrocytes possess more diverse functions and phenotypes than previously predicted. In the present focused review, we summarize the evidence showing that astrocytes are playing profound roles in the disease process of amyotrophic lateral sclerosis. Read More

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November 2018

Imaging quantum fluctuations near criticality.

Nat Phys 2018 Dec 20;14(12):1205-1210. Epub 2018 Aug 20.

Department of Physics and Institute of Nanotechnology and Advanced Materials, Bar Ilan University Ramat Gan, Israel.

A quantum phase transition (QPT) occurs between two competing phases of matter at zero temperature, driven by quantum fluctuations. Though the presence of these fluctuations is well established, they have not been locally imaged in space and their local dynamics has not been studied so far. We use a scanning superconducting quantum interference device to image quantum fluctuations in the vicinity of the QPT from a superconductor to an insulator. Read More

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December 2018

Serotonergic Input to Orexin Neurons Plays a Role in Maintaining Wakefulness and REM Sleep Architecture.

Front Neurosci 2018 30;12:892. Epub 2018 Nov 30.

International Institute for Integrative Sleep Medicine, University of Tsukuba, Tsukuba, Japan.

Neurons expressing neuropeptide orexins (hypocretins) in the lateral hypothalamus (LH) and serotonergic neurons in the dorsal raphe nucleus (DR) both play important roles in the regulation of sleep/wakefulness states, and show similar firing patterns across sleep/wakefulness states. Orexin neurons send excitatory projections to serotonergic neurons in the DR, which express both subtypes of orexin receptors (Mieda et al., 2011), while serotonin (5-HT) potently inhibits orexin neurons through activation of 5HT receptors (5HT1ARs). Read More

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November 2018

Invasive and Non-invasive Stimulation of the Obese Human Brain.

Authors:
Burkhard Pleger

Front Neurosci 2018 29;12:884. Epub 2018 Nov 29.

Department of Neurology, BG University Clinic Bergmannsheil, Ruhr-University Bochum, Bochum, Germany.

Accumulating evidence suggests that non-invasive and invasive brain stimulation may reduce food craving and calorie consumption rendering these techniques potential treatment options for obesity. Non-invasive transcranial direct current stimulation (tDCS) or repetitive transcranial magnet stimulation (rTMS) are used to modulate activity in superficially located executive control regions, such as the dorsolateral prefrontal cortex (DLPFC). Modulation of the DLPFC's activity may alter executive functioning and food reward processing in interconnected dopamine-rich regions such as the striatum or orbitofrontal cortex. Read More

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November 2018

The performance of serum cryptococcal capsular polysaccharide antigen test, histopathology and culture of the lung tissue for diagnosis of pulmonary cryptococcosis in patients without HIV infection.

Infect Drug Resist 2018 28;11:2483-2490. Epub 2018 Nov 28.

Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325015, Zhejiang, China,

Background: Clinicians may fail to make an early diagnosis of pulmonary cryptococcosis (PC) without HIV infection. Serum cryptococcal capsular polysaccharide antigen (CrAg) test, histopathology and culture of lung tissue play different roles in diagnosis of PC.

Objective: To investigate the performance of serum CrAg test, histopathology and culture of the lung tissue in diagnosis of PC without HIV infection. Read More

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November 2018

WNT10A variants in relation to nonsyndromic hypodontia in eastern Slovak population.

J Genet 2018 Dec;97(5):1169-1177

Department of Biology, Faculty of Humanities and Natural Sciences, University of Presov, Presov, Slovakia.

Nonsyndromic hypodontia is a congenital absence of less than six permanent teeth, with a most common subtype maxillary lateral incisor agenesis (MLIA). Mutations in several genes have been described in severe tooth agenesis. The aim of this study was to search for the variants in wingless-type MMTV-integration site family member (), paired box 9 () and axis inhibitor 2 () genes, and investigate their potential role in the pathogenesis of non-syndromic hypodontia. Read More

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December 2018

Surgical treatment of lateral and posterior process fractures of the talus: Mid-term results of 15 cases after 7 years.

Foot Ankle Surg 2018 Nov 29. Epub 2018 Nov 29.

Department of Trauma Surgery, Otto-von-Guericke University, Leipziger Str. 44 Magdeburg, Germany.

Background: We retrospectively evaluated the mid-term results of surgery for talar process fractures (lateral and posterior processes) and exploratively analyzed parameters that potentially impact treatment outcomes.

Methods: Fifteen patients who underwent internal fixation (January 2000 to December 2015) were examined for radiological and clinical functional outcomes. The independent parameters evaluated were age, sex, extent of general injury, soft-tissue damage, surgical latency, and fracture type. Read More

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November 2018

Effect of meniscus repair on pivot-shift during anterior cruciate ligament reconstruction: Objective evaluation using triaxial accelerometer.

Knee 2018 Dec 13. Epub 2018 Dec 13.

Department of Joint Surgery and Sports Medicine, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan; Department of Orthopaedic Surgery, Tokyo Medical and Dental University Hospital of Medicine, Bunkyo-ku, Tokyo, Japan. Electronic address:

Background: Some types of meniscus tear, especially lateral meniscus tear, have been reported to be associated with rotatory knee laxity. However, precise information regarding the effect of meniscus repair on rotatory laxity is limited. The purpose of this study was to investigate the effects of lateral and medial meniscus repair on rotatory laxity in anterior cruciate ligament (ACL) injured knees. Read More

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December 2018

Repeatability of measuring knee flexion angles with wearable inertial sensors.

Knee 2018 Dec 13. Epub 2018 Dec 13.

Lawson Health Research Institute, Robarts Research Institute, Department of Medical Biophysics, Department of Surgery, Western University, London, ON, Canada.

Background: As assessment with inertial-measurement-units (IMUs) increases in research and in clinics, it is important to be aware of the repeatability of these sensors. The objectives of this experiment were to evaluate the measurement repeatability of IMU joint angles using a repeatable robot controller and an anthropomorphic leg phantom and to determine effects of joint speed and sensor positioning on the angles collected by these sensors. Comparisons to an electro-goniometer and three-dimensional (3D) motion capture cameras were also completed. Read More

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December 2018

Allatostatin-C/AstC-R2 Is a Novel Pathway to Modulate the Circadian Activity Pattern in Drosophila.

Curr Biol 2018 Dec 4. Epub 2018 Dec 4.

Howard Hughes Medical Institute and National Center for Behavioral Genomics, Brandeis University, Waltham, MA 02454, USA. Electronic address:

Seven neuropeptides are expressed within the Drosophila brain circadian network. Our previous mRNA profiling suggested that Allatostatin-C (AstC) is an eighth neuropeptide and specifically expressed in dorsal clock neurons (DN1s). Our results here show that AstC is, indeed, expressed in DN1s, where it oscillates. Read More

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December 2018

Predominant Striatal Input to the Lateral Habenula in Macaques Comes from Striosomes.

Curr Biol 2018 Dec 6. Epub 2018 Dec 6.

McGovern Institute for Brain Research and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address:

Striosomes, neurochemically specialized modules in the striatum, are thought to be nodes in circuits extending, via basal ganglia pathways, from mood-related neocortical regions to dopamine-containing neurons of the substantia nigra. Yet striosomes have remained beyond the reach of electrophysiological methods to identify them, especially in non-human primates. Such work is needed for translational as well as for basic science. Read More

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December 2018

Timed Collinear Activation of Hox Genes during Gastrulation Controls the Avian Forelimb Position.

Curr Biol 2018 Dec 6. Epub 2018 Dec 6.

Department of Developmental and Stem Cell Biology, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris, Cedex 15, France; CNRS UMR3738, 25 rue du Dr Roux, 75015 Paris, France. Electronic address:

Limb position along the body is highly consistent within one species but very variable among vertebrates. Despite major advances in our understanding of limb patterning in three dimensions, how limbs reproducibly form along the antero-posterior axis remains largely unknown. Hox genes have long been suspected to control limb position; however, supporting evidences are mostly correlative and their role in this process is unclear. Read More

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December 2018

Quality of life related to symptomatic outcomes in patients with vestibular schwannomas: A Canadian Centre perspective.

Am J Otolaryngol 2018 Nov 22. Epub 2018 Nov 22.

Division of Neurosurgery, QEII Halifax Infirmary Site, 3rd Floor, 1796 Summer Street, Halifax, NS B3H 3A7, Canada; Maritime Lateral Skull Base Clinic: Divisions of Neurosurgery, OtolaryngologyHead & Neck Surgery, Canada; Department of Radiation Oncology, Dalhousie University, QEII Health Sciences Centre, 3rd floor Dickson Building, 5820 University Avenue, Halifax, NS B3H 1Y9, Canada.

Patients with vestibular schwannomas (VS) typically present with hearing loss and tinnitus as well as variable cranial nerve dysfunctions. Surgical resection, stereotactic radiotherapy and/or conservative management employing serial magnetic resonance or computed tomography imaging serve as the main treatment options. Quality of life (QoL) may be impacted by the extent of tumour burden and exacerbated or relieved by treatment. Read More

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November 2018

Correction of distal femoral valgus deformities with fixator-assisted plating: How accurate is the correction?

Acta Orthop Traumatol Turc 2018 Dec 13. Epub 2018 Dec 13.

Hacettepe University, Department of Orthopaedics and Traumatology, Turkey.

Objective: The aim of this study was to evaluate the results of fixator assisted correction of the distal femoral valgus deformities and the precision of the correction.

Methods: Seventeen extremities of 13 patients (7 women and 6 men; mean age: 16 ± 5.4 years) who had fixator assisted plating of the distal femur for genu valgum deformity were evaluated. Read More

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December 2018

Safety and efficacy of nabiximols on spasticity symptoms in patients with motor neuron disease (CANALS): a multicentre, double-blind, randomised, placebo-controlled, phase 2 trial.

Lancet Neurol 2018 Dec 13. Epub 2018 Dec 13.

Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy. Electronic address:

Background: Spasticity is a major determinant of disability and decline in quality of life in patients with motor neuron disease. Cannabinoids have been approved for symptomatic treatment of spasticity in multiple sclerosis. We investigated whether cannabinoids might also reduce spasticity in patients with motor neuron disease. Read More

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December 2018

The effect of axial compression and distraction on cervical facet mechanics during anterior shear, flexion, axial rotation, and lateral bending motions.

J Biomech 2018 Dec 5. Epub 2018 Dec 5.

Centre for Orthopaedic & Trauma Research, Adelaide Medical School, The University of Adelaide, South Australia, Australia; Adelaide Spinal Research Group, Adelaide Medical School, The University of Adelaide, South Australia, Australia; School of Mechanical Engineering, The University of Adelaide, South Australia, Australia. Electronic address:

The subaxial cervical facets are important load-bearing structures, yet little is known about their mechanical response during physiological or traumatic intervertebral motion. Facet loading likely increases when intervertebral motions are superimposed with axial compression forces, increasing the risk of facet fracture. The aim of this study was to measure the mechanical response of the facets when intervertebral axial compression or distraction is superimposed on constrained, non-destructive shear, bending and rotation motions. Read More

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December 2018

Tac1-Expressing Neurons in the Periaqueductal Gray Facilitate the Itch-Scratching Cycle via Descending Regulation.

Neuron 2018 Dec 5. Epub 2018 Dec 5.

Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science & Intelligence Technology, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China. Electronic address:

Uncontrollable itch-scratching cycles lead to serious skin damage in patients with chronic itch. However, the neural mechanism promoting the itch-scratching cycle remains elusive. Here, we report that tachykinin 1 (Tac1)-expressing glutamatergic neurons in the lateral and ventrolateral periaqueductal gray (l/vlPAG) facilitate the itch-scratching cycle. Read More

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December 2018

An analysis of perioperative outcomes following cervical abscess drainage in children under 2 years.

Int J Pediatr Otorhinolaryngol 2019 Jan 28;116:125-129. Epub 2018 Oct 28.

Department of Otolaryngology - Head and Neck Surgery, West Virginia University, 1 Medical Center Drive, Morgantown, WV, 26506, USA.

Objective: To identify risk factors and determine perioperative morbidity of children under 2 years of age undergoing cervical abscess drainage.

Methods: Patients who underwent cervical abscess drainage 1-18 years of age were queried via the ACS-National Surgical Quality Improvement Program-Pediatric (NSQIP-P) database (2012-2015). Analyzed outcomes include length of stay, operative time, readmission/reoperation rate, and postoperative complications. Read More

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January 2019

Double-exponential kinetics of binding and redistribution of the fluorescent dyes in cell membranes witness for the existence of lipid microdomains.

Biochem Biophys Res Commun 2018 Dec 13. Epub 2018 Dec 13.

Laboratory of Nanobiotechnologies, O.V. Palladin Institute of Biochemistry of the NAS of Ukraine, Leontovicha Str. 9, Kyiv, 01030, Ukraine.

New technique of detecting lateral heterogeneity of the plasma membrane of living cells by means of membrane-binding fluorescent dyes is proposed. The kinetics of dye incorporation into the membrane or its lateral diffusion inside the membrane is measured and decomposed into exponential components by means of the Maximum Entropy Method. Two distinct exponential components are obtained consistently in all cases for several fluorescent dyes, two different cell lines and in different types of experiments including spectroscopy, flow cytometry and fluorescence recovery after photobleaching. Read More

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December 2018

Characterization of Flow Efficiency, Pulsatility, and Respiratory Variability in Different Types of Fontan Circuits Using Quantitative Parameters.

Yonsei Med J 2019 Jan;60(1):56-64

Division of Cardiovascular Surgery, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Korea.

Purpose: Details on the hemodynamic differences among Fontan operations remain unclear according to respiratory and cardiac cycles. This study was undertaken to investigate hemodynamic characteristics in different types of Fontan circulation by quantification of blood flow with the combined influence of cardiac and respiratory cycles.

Materials And Methods: Thirty-five patients [10 atriopulmonary connections (APC), 13 lateral tunnels (LT), and 12 extracardiac conduits (ECC)] were evaluated, and parameters were measured in the superior vena cava, inferior vena cava (IVC), hepatic vein (HV), baffles, conduits, and left and right pulmonary artery. Read More

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January 2019

Enigma portal case: Phaeohyphomycosis by fine needle aspiration.

Cytopathology 2018 Dec 16. Epub 2018 Dec 16.

Department of Pathology, Duke University Medical Center.

48-year-old male History of multiple myeloma, clinically stable Now presenting with subcutaneous nodule near the left lateral epicondyle which had been present for "years" but had recently enlarged. The patient noted a possible remote minor trauma to the area. This article is protected by copyright. Read More

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December 2018
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Insular Resting State Functional Connectivity is Associated with Gut Microbiota Diversity.

Eur J Neurosci 2018 Dec 16. Epub 2018 Dec 16.

Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, Texas, 77030, USA.

The gut microbiota has recently gained attention as a possible modulator of brain activity. A number of reports suggest that the microbiota may be associated with neuropsychiatric conditions such as major depressive disorder, autism, and anxiety. The gut microbiota is thought to influence the brain via vagus nerve signaling, among other possible mechanisms. Read More

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December 2018
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Arbuscular mycorrhizal fungi possess a CLAVATA3/Endosperm surrounding region-related gene that positively regulates symbiosis.

New Phytol 2018 Dec 16. Epub 2018 Dec 16.

Laboratoire de Recherche en Sciences Végétales, Université de Toulouse, CNRS, UPS, France.

The arbuscular mycorrhizal (AM) symbiosis is a beneficial association established between land plants and the members of a subphylum of fungi, the Glomeromycotina. How the two symbiotic partners regulate their association is still enigmatic. Secreted fungal peptides are candidates for regulating this interaction. Read More

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December 2018

Heterogeneous brain FDG-PET metabolic patterns in patients with C9orf72 mutation.

Neurol Sci 2018 Dec 15. Epub 2018 Dec 15.

Vita-Salute San Raffaele University, Milan, Italy.

Objective: The hexanucleotide repeat expansion in C9orf72 is an associated genetic cause in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). In the "ALS/FTD" spectrum prevails clinical heterogeneity and an in vivo knowledge of the underling brain dysfunction in patients carrying C9orf72 mutation remain limited and only described at group level. The study aimed to assess the brain metabolic alterations characterizing patients with C9orf72 mutation using FDG-PET in single individuals. Read More

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December 2018
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Pharmacokinetics of meropenem in plasma and cerebrospinal fluid in patients with intraventricular hemorrhage after lateral ventricle drainage.

Eur J Clin Pharmacol 2018 Dec 15. Epub 2018 Dec 15.

Department of Emergency Internal Medicine, The First Affiliated Hospital of Bengbu Medical College, Bengbu, 233004, China.

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December 2018

Barotraumatic blowout fracture of the orbit after sneezing: Cone beam CT demonstration.

Clin Ter 2018 Nov-Dec;169(6):e265-e268

Section of Diagnostic Imaging - DIBIMED, University of Palermo, Palermo, Italy.

A 40-year-old man with no history of trauma or previous sinus surgery complained sudden right diplopia after vigorous sneezing. The patient was submitted elsewhere to a MRI study for persisting diplopia, with inconclusive findings. One week later the patient was submitted to a maxillofacial cone beam CT (CBCT) in our Institution. Read More

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December 2018

Integrated Analysis of the Endoscopic, Pathological and Molecular Characteristics of Colorectal Tumorigenesis.

Digestion 2018 Dec 14;99(1):33-38. Epub 2018 Dec 14.

Department of Molecular Diagnostic Pathology, School of Medicine, Iwate Medical University, Morioka, Japan.

Background: Colorectal cancers (CRCs) develop through the accumulation of genetic and epigenetic alterations of oncogenes and tumor suppressor genes. In addition to the well-characterized adenoma-carcinoma sequence, the serrated neoplasia pathway is now recognized as an alternative pathway for CRC development.

Summary: Through analysis of the colonoscopic, pathological, and molecular features of colorectal tumors, we identified a novel microsurface structure characteristic of serrated lesions. Read More

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December 2018
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Atlantoaxial fixation using C1 posterior arch screws: feasibility study, morphometric data, and biomechanical analysis.

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J Neurosurg Spine 2018 Dec 14:1-9. Epub 2018 Dec 14.

OBJECTIVEC1-2 is a highly mobile complex that presents unique surgical challenges to achieving biomechanical rigidity and fusion. Posterior wiring methods have been largely replaced with segmental constructs using the C1 lateral mass, C1 pedicle, C2 pars, and C2 pedicle. Modifications to reduce surgical morbidity led to the development of C2 laminar screws. Read More

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December 2018

Clinically applicable delineation of the pallidal sensorimotor region in patients with advanced Parkinson's disease: study of probabilistic and deterministic tractography.

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J Neurosurg 2018 Dec 14:1-12. Epub 2018 Dec 14.

OBJECTIVEDeep brain stimulation (DBS) is an effective procedure in improving motor symptoms for patients with advanced Parkinson's disease (PD) through the use of high-frequency stimulation. Although one of the most commonly used target sites for DBS, sensorimotor regions of the globus pallidus interna (GPi) have yet to be thoroughly described with advanced neuroimaging analysis in vivo for human subjects. Furthermore, many imaging studies to date have been performed in a research setting and bring into question the feasibility of their applications in a clinical setting, such as for surgical planning. Read More

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December 2018

Evaluation of a more ventral starting point for thoracic pedicle screws: higher maximal insertional arc and more medial and safer screw angulation.

Authors:

J Neurosurg Spine 2018 Dec 14:1-7. Epub 2018 Dec 14.

OBJECTIVETo demonstrate that a more ventral starting point for thoracic pedicle screw insertion, produced by aggressively removing the dorsal transverse process bone down to the superior articular facet (SAF), results in a larger margin for error and more medial screw angulation compared to the traditional dorsal starting point (DSP). The margin for error will be quantified by the maximal insertional arc (MIA).METHODSThe study population included 10 consecutive operative patients with adult idiopathic scoliosis who underwent primary surgery. Read More

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December 2018

Evaluation of functional ankle instability assessed by an instrumented wobble board.

Phys Ther Sport 2018 Dec 8;35:133-138. Epub 2018 Dec 8.

Physiotherapy Department, University College of Northern Denmark, UCN, Selma Lagerloffsvej 2, DK-9220, Aalborg, Denmark.

Objectives: Ankle sprains often lead to a history of recurrent injuries and functional joint instability. This study evaluated a new method for assessing functional impairment in patients with chronic ankle instability.

Design: Case-control study for construct validation purpose. Read More

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December 2018
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