279,151 results match your criteria Lateral Collateral Knee Ligament Injury


Lateral hypothalamic Mc3R-expressing neurons modulate locomotor activity, energy expenditure and adiposity in male mice.

Endocrinology 2018 Dec 11. Epub 2018 Dec 11.

Dept. of Pediatrics, Division of Endocrinology, Michigan Medicine, Ann Arbor, MI.

The central melanocortin (Mc) system plays a crucial role in the control of energy balance. While the decreased energy expenditure and increased adiposity of Mc-3 receptor (Mc3R)-null mice suggest the importance of Mc3R-regulated neurons in energy homeostasis, the roles for specific subsets of Mc3R neurons in energy balance have yet to be determined. Because the lateral hypothalamic area (LHA) contributes to the control of energy expenditure and feeding, we generated Mc3rcre mice to determine the roles of LHA Mc3R (Mc3RLHA) neurons in energy homeostasis. Read More

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December 2018

Axon-Seq Decodes the Motor Axon Transcriptome and Its Modulation in Response to ALS.

Stem Cell Reports 2018 Dec;11(6):1565-1578

Department of Neuroscience, Karolinska Institutet, Stockholm 171 77, Sweden. Electronic address:

Spinal motor axons traverse large distances to innervate target muscles, thus requiring local control of cellular events for proper functioning. To interrogate axon-specific processes we developed Axon-seq, a refined method incorporating microfluidics, RNA sequencing (RNA-seq), and bioinformatic quality control. We show that the axonal transcriptome is distinct from that of somas and contains fewer genes. Read More

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December 2018

Gene network analysis of poplar root transcriptome in response to drought stress identifies a PtaJAZ3PtaRAP2.6-centered hierarchical network.

PLoS One 2018 12;13(12):e0208560. Epub 2018 Dec 12.

Forest Resources and Environmental Science, Michigan Technological University, Houghton, MI, United States of America.

Using time-series transcriptomic data from poplar roots undergoing polyethylene glycol (PEG)-induced drought stress, we built a genetic network model of the involved putative molecular responses. We found that the network resembled a hierarchical structure. The highest hierarchical level in this structure is occupied by 9 genes, which we called superhubs because they were primarily connected to 18 hub genes, which are then connected to 2,934 terminal genes. Read More

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December 2018

Spatial impacts of a multi-individual grave on microbial and microfaunal communities and soil biogeochemistry.

PLoS One 2018 12;13(12):e0208845. Epub 2018 Dec 12.

Department of Biosystems Engineering and Soil Science, University of Tennessee, Knoxville, Tennessee, United States of America.

Decomposing vertebrates, including humans, result in pronounced changes in surrounding soil biogeochemistry, particularly nitrogen (N) and carbon (C) availability, and alter soil micro- and macrofauna. However, the impacts of subsurface human decomposition, where oxygen becomes limited and microbial biomass is generally lower, are far less understood. The goals of this study were to evaluate the impact of human decomposition in a multi-individual, shallow (~70 cm depth) grave on soil biogeochemistry and soil microbial and nematode communities. Read More

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December 2018

Assessing the potential of sputtered gold nanolayers in mass spectrometry imaging for metabolomics applications.

PLoS One 2018 12;13(12):e0208908. Epub 2018 Dec 12.

Department of Electronic Engineering, Universitat Rovira i Virgili, Tarragona, Spain.

Mass spectrometry imaging (MSI) is a molecular imaging technique that maps the distribution of molecules in biological tissues with high spatial resolution. The most widely used MSI modality is matrix-assisted laser desorption/ionization (MALDI), mainly due to the large variety of analyte classes amenable for MALDI analysis. However, the organic matrices used in classical MALDI may impact the quality of the molecular images due to limited lateral resolution and strong background noise in the low mass range, hindering its use in metabolomics. Read More

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December 2018

Development of a recombinase polymerase based isothermal amplification combined with lateral flow assay (HLB-RPA-LFA) for rapid detection of "Candidatus Liberibacter asiaticus".

PLoS One 2018 12;13(12):e0208530. Epub 2018 Dec 12.

Plant Virology Laboratory, ICAR-Indian Institute of Horticulture, Bengaluru, Karnataka, India.

Huanglongbing (HLB) or citrus greening is highly destructive disease that is affecting the citrus industry worldwide and it has killed millions of citrus plants globally. HLB is caused by the phloem limited, Gram negative, non-culturable, alpha-proteobacterium, 'Candidatus Liberibacter asiaticus'. Currently, polymerase chain reaction (PCR) and real time PCR have been the gold standard techniques used for detection of 'Ca. Read More

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December 2018

New skeletal material sheds light on the palaeobiology of the Pleistocene marsupial carnivore, Thylacoleo carnifex.

PLoS One 2018 12;13(12):e0208020. Epub 2018 Dec 12.

Ecology and Evolution, College of Science and Engineering, Flinders University, Adelaide, South Australia, Australia.

The extinct marsupial 'lion' Thylacoleo carnifex was Australia's largest mammalian carnivore. Despite being the topic of more discussion than any other extinct Australian marsupial (excepting perhaps the Thylacine), basic aspects of its palaeobiology, including its locomotory repertoire, remain poorly understood. Recent discoveries allowed the first reconstruction of an entire skeleton including the first complete tail and hitherto-unrecognised clavicles. Read More

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December 2018

Live nanoscopic to mesoscopic topography reconstruction with an optical microscope for chemical and biological samples.

PLoS One 2018 12;13(12):e0207881. Epub 2018 Dec 12.

LAI, Aix Marseille Univ, CNRS, INSERM, Marseille, France.

Macroscopic properties of physical and biological processes like friction, wetting, and adhesion or cell migration are controlled by interfacial properties at the nanoscopic scale. In an attempt to bridge simultaneously investigations at different scales, we demonstrate here how optical microscopy in Wet-Surface Ellipsometric Enhanced Contrast (Wet-SEEC) mode offers imaging and measurement of thin films at solid/liquid interfaces in the range 1-500 nm with lateral optical resolution. A live, label-free and noninvasive methodology integrated with microfluidic devices allowed here characterization of polymers and proteins patterns together with corresponding phenotypes of living cells. Read More

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December 2018

A new microendemic species of the deep-water catshark genus Bythaelurus (Carcharhiniformes, Pentanchidae) from the northwestern Indian Ocean, with investigations of its feeding ecology, generic review and identification key.

PLoS One 2018 12;13(12):e0207887. Epub 2018 Dec 12.

Center of Natural History, University of Hamburg, Hamburg, Germany.

A new deep-water catshark, Bythaelurus stewarti, is described based on 121 examined specimens caught on the Error Seamount (Mount Error Guyot) in the northwestern Indian Ocean. The new species differs from all congeners in the restricted distribution, a higher spiral valve turn count and in the morphology of the dermal denticles. It is distinguished from its morphologically and geographically closest congener, B. Read More

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December 2018

A Quartet of Elastic Stable Intramedullary Nails for More Challenging Pediatric Femur Fractures.

J Pediatr Orthop 2019 Jan;39(1):e12-e17

Children's Healthcare of Atlanta.

Introduction: The insertion of 2 elastic stable intramedullary nails (ESINs) is a common treatment for pediatric femur fractures. However, the use of this technique in length-unstable or metadiaphyseal fractures has historically been associated with higher complication rates. To improve stability, the addition of a third ESIN has been assessed biomechanically and clinically, but the addition of a fourth nail has only been evaluated biomechanically. Read More

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January 2019

Management of Long-Term Complications in the Setting of Lateral Meniscal Deficiency After Saucerization of a Discoid Lateral Meniscus in an Adolescent Patient: A Case Report and Review of the Literature.

JBJS Case Connect 2018 Dec 12. Epub 2018 Dec 12.

Elite Sports Medicine, Division of Orthopedic Surgery, Connecticut Children's Medical Center, University of Connecticut School of Medicine, Farmington, Connecticut.

Case: A 14-year-old adolescent with bilateral discoid menisci who had previously undergone discoid meniscal saucerization presented with pain and mechanical knee symptoms bilaterally. She had a torn left discoid lateral meniscus, a right lateral meniscal deficiency with an associated osteochondral defect, and valgus collapse of the right femur. She underwent successful repair of the left discoid meniscus as well as a femoral osteotomy, a meniscal transplant, and an osteochondral allograft transplantation in the right knee. Read More

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December 2018

Two-Team Surgical Approach to Improve Retroperitoneal Nerve Identification in the Treatment of Groin Pain.

Ann Plast Surg 2019 Jan;82(1):82-84

Greater Baltimore Medical Center, Towson, Maryland.

Background: An estimated 700,000 groin hernia repairs are performed in the United States each year. Studies have shown that up to 50% of patients who undergo groin hernia repair are affected by persistent pain beyond the first few days after surgery. At 2 to 5 years after either open or laparoscopic, mesh or without mesh, 10% to 12% of these patients will have persistent and disabling pain. Read More

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January 2019

Surgical Algorithmic Approach to Facilitate Primary Closure of the Anterolateral Thigh Flap Donor Site in Head and Neck Reconstruction.

Ann Plast Surg 2018 Dec 6. Epub 2018 Dec 6.

Department of Plastic and Reconstructive Surgery, Ditmanson Medical Foundation Chiayi Christian Hospital, Chiayi City, Taiwan.

Background: Use of the anterolateral thigh (ALT) flap has gained popularity in head and neck reconstruction. However, donor sites that cannot achieve primary closure are reported to have poorer functional and aesthetic outcomes. Therefore, we propose an algorithm to facilitate primary closure of the donor site. Read More

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December 2018
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Is anterior guidance a key factor on planning implant treatment for free-end missing in the posterior mandible?

J Oral Implantol 2018 Dec 12. Epub 2018 Dec 12.

1 Kyushu Dental University Department of Oral Reconstruction and Rehabilitation Kyushu Dental University.

To perform safe implant treatment, the anatomical structure and bone quality at implant placement sites are evaluated based on a patient's CT data, but there is no definite method to determine placement sites and the appropriate number of implants. The objective of this study was to investigate the influence of the number and arrangement of implants on the stress distribution in 3-unit posterior fixed partial dentures for the posterior mandible by mechanical analysis using the finite element method. Three-dimensional finite element analysis models were constructed from the CT data of a patient with missing mandibular teeth (Nos. Read More

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December 2018

Cdc42 negatively regulates endocytosis during apical membrane maintenance in live animals.

Mol Biol Cell 2018 Dec 12:mbcE18100615. Epub 2018 Dec 12.

Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 37 Convent Dr. Rm 2050B, Bethesda, MD, 20892 USA.

Lumen establishment and maintenance are fundamental for tubular organs physiological functions. Most of the studies investigating the mechanisms regulating this process have been carried out in cell cultures or in smaller organisms, whereas little has been done in mammalian model systems in vivo. Here we used the salivary glands of live mice to examine the role of the small GTPase Cdc42 in the regulation of the homeostasis of the intercellular canaliculi, a specialized apical domain of the acinar cells, where protein and fluid secretion occur. Read More

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December 2018

Designing spatially distributed gene regulatory networks to elicit contrasting patterns.

ACS Synth Biol 2018 Dec 12. Epub 2018 Dec 12.

Pattern formation and differential interactions are important for microbial consortia to divide labor and perform complex functions. To obtain further insight into such interactions, we present a computational method for simulating physically separated microbial colonies each implementing different gene regulatory networks. We validate our theory by experimentally demonstrating control over gene expression patterns in a diffusion-mediated lateral inhibition circuit. Read More

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December 2018

Mesoscopic simulation study on the structural transition of comb-shaped block copolymer lamellae on chemically patterned substrates: from vertical to lateral.

Phys Chem Chem Phys 2018 Dec 12. Epub 2018 Dec 12.

School of Chemistry and Chemical Engineering, Sichuan University of Arts and Science, Dazhou, Sichuan 635000, P. R. China.

Directed self-assembly of polymers on chemically homogeneous and heterogeneous patterns is of considerable interest for nanolithography and nanofluidic devices. By employing dissipative particle dynamics (DPD) technology, we explore the nanoscale phase separation of comb-like block copolymers (CBCPs) confined at chemically homogeneous and heterogeneous substrates. Herein, the geometric and energetic influences of striped substrates on the microphases are firstly studied using various geometries of annular stripes for the heterogeneous substrates. Read More

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December 2018

The London - van der Waals Force Field of a Chemically Patterned Surface to Enable Selective Adhesion.

Langmuir 2018 Dec 12. Epub 2018 Dec 12.

The London - van der Waals (L-vdW) force between a particle and a surface strongly depends on the topography and the chemical properties of the interacting surfaces. While a great deal of work has been done to understand the effect of topographical heterogeneity on the L-vdW adhesion, the role of chemical heterogeneity has been discussed only rarely. This study makes an attempt to quantify the magnitude and range of the L-vdW force acting on a spherical particle in the vicinity of a chemically patterned surface. Read More

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December 2018

Smaller left anterior cingulate cortex in non-bipolar relatives of patients with bipolar disorder.

Braz J Psychiatr 2018 Dec 6. Epub 2018 Dec 6.

UT Center of Excellence on Mood Disorders, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, Houston, TX, USA.

Objective: Bipolar disorder (BD) is highly heritable. The present study aimed at identifying brain morphometric features that could represent markers of BD vulnerability in non-bipolar relatives of bipolar patients.

Methods: In the present study, structural magnetic resonance imaging brain scans were acquired from a total of 93 subjects, including 31 patients with BD, 31 non-bipolar relatives of BD patients, and 31 healthy controls. Read More

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December 2018

Topography of 11C-Pittsburgh compound B uptake in Alzheimer's disease: a voxel-based investigation of cortical and white matter regions.

Braz J Psychiatr 2018 Dec 6. Epub 2018 Dec 6.

Núcleo de Apoio à Pesquisa em Neurociência Aplicada (NAPNA), USP, São Paulo, SP, Brazil.

Objective: To compare results of positron emission tomography (PET) with carbon-11-labeled Pittsburgh compound B (11C-PIB) obtained with cerebellar or global brain uptake for voxel intensity normalization, describe the cortical sites with highest tracer uptake in subjects with mild Alzheimer's disease (AD), and explore possible group differences in 11C-PIB binding to white matter.

Methods: 11C-PIB PET scans were acquired from subjects with AD (n=17) and healthy elderly controls (n=19). Voxel-based analysis was performed with statistical parametric mapping (SPM). Read More

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December 2018

Directional freezing of binary colloidal suspensions: a model for size fractionation of graphene oxide.

Soft Matter 2018 Dec 12. Epub 2018 Dec 12.

Center of Soft Matter Physics and Its Applications, Beihang University, Beijing 100191, China.

The performance of graphene oxide (GO)-based materials strongly depends on the lateral size and size distribution of GO nanosheets. Various methods are employed to prepare GO nanosheets with a narrow size distribution. One promising method was proposed recently, directional freezing of a GO aqueous dispersion at a controlled growth rate of the freezing front. Read More

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December 2018

Anatomical Risk Factors of Anterior Cruciate Ligament Injury.

Chin Med J (Engl) 2018 Dec;131(24):2960-2967

Department of Orthopaedics, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215004, China.

Background: Nowadays, the anterior cruciate ligament (ACL) injury has been one of the most common diseases of the knee joint. The relationships between the ACL injury and the anatomical structures are still controversial. This study aimed to identify the anatomical risk factors of ACL injury by magnetic resonance imaging (MRI) of the knee. Read More

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December 2018
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Clinical Features and Prognostic Risk Factors of Choroid Plexus Tumors in Children.

Chin Med J (Engl) 2018 Dec;131(24):2938-2946

Department of Neurosurgery, Beijing Tiantan Hospital; Department of Neurosurgery, Beijing Neurosurgical Institute, Capital Medical University, Beijing 100050, China.

Background: Decision-making concerning the treatment of choroid plexus tumor (CPT) in pediatric patients remains a topic of considerable debate. The aim of this work was to describe clinical features and prognostic risk factors of CPT in the pediatric population and to provide theoretical opinions regarding clinical decisions for CPT.

Methods: The data of 96 patients with CPT and younger than 14 years were retrospectively analyzed. Read More

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December 2018

Monitoring Value of Multimodal Magnetic Resonance Imaging in Disease Progression of Amyotrophic Lateral Sclerosis: A Prospective Observational Study.

Chin Med J (Engl) 2018 Dec;131(24):2904-2909

Department of Neurology, Peking Union Medical College Hospital; Neuroscience Center, Chinese Academy of Medical Sciences, Beijing 100730, China.

Background: Ongoing efforts have been made to identify new neuroimaging markers to track amyotrophic lateral sclerosis (ALS) progression. This study aimed to explore the monitoring value of multimodal magnetic resonance imaging (MRI) in the disease progression of ALS.

Methods: From September 2015 to March 2017, ten patients diagnosed with ALS in Peking Union Medical College Hospital completed head MRI scans at baseline and during follow-up. Read More

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December 2018

Network strategy to investigate differential pathways in sporadic amyotrophic lateral sclerosis.

J Cancer Res Ther 2018 Dec;14(Supplement):S1057-S1062

Department of Internal Medicine of TCM, Zhonglu Hospital, Shandong University of TCM, Jinan, Shandong Province, China.

Objective: The objective of this paper was to investigate differential pathways in sporadic amyotrophic lateral sclerosis (SALS) based on pathway network analysis.

Materials And Methods: To achieve this goal, first, differentially expressed genes (DEGs) between SALS and normal controls were identified, and a target network was defined as DEGs correlated interactions from the search tool for the retrieval of interacting genes/proteins (STRING). Second, topological centrality analysis was conducted on the target network to identify hub genes and hub network. Read More

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December 2018

Evaluation of levels of interleukin-6, interleukin-8 and some haematologic parameters of dogs with cutaneous wounds.

Cytokine 2019 Jan 28;113:128-138. Epub 2018 Jun 28.

Department of Veterinary Medicine, ABU, Zaria, Nigeria.

The aim of the study was to investigate the time-course of serum and wound fluids interleukin (IL)-6 and IL-8 levels in dogs with cutaneous wounds and their relationship with some haematologic parameters. The experimental group comprised of six adult dogs that underwent surgery with wounds (n = 6) on the mid lateral aspect of the right antebrachium; and control group of six, apparently, healthy intact (free from cutaneous wounds) adult dogs, comprising equal number of both sexes. Vital signs evaluated were within normal limits. Read More

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January 2019

Giant Modal Gain Coefficients in Colloidal II-VI Nanoplatelets.

Nano Lett 2018 Dec 12. Epub 2018 Dec 12.

Modal gain coefficient is a key figure of merit for a laser material. Previously, net modal gain coefficients larger than a few thousand cm-1 were achieved in II-VI and III-V semiconductor gain media, but this required operation at cryogenic temperatures. In this work, using pump-fluence-dependent variable-stripe-length measurements, we show that colloidal CdSe nanoplatelets enable giant modal gain coefficients at room temperature, up to 6,600 cm-1 under pulsed optical excitation. Read More

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December 2018

Laterally Extended Pelvic Resection for Gynaecological Malignancies: A Multicentric Experience with Out-of-the-Box Surgery.

Ann Surg Oncol 2018 Dec 11. Epub 2018 Dec 11.

Gynaecologic Oncology Center, Department of Obstetrics and Gynecology, First Faculty of Medicine, Charles University in Prague, General University Hospital in Prague, Prague, Czech Republic.

Purpose: To evaluate morbidity and oncological outcome in a multicentre series of women with gynaecological malignancies infiltrating pelvic side wall (PSW) that received laterally extended pelvic resection (LEPR).

Methods: Patients operated between 2007 and 2017 at three institutions were included. LEPR was defined as an en bloc lateral resection of a pelvic tumour involving sidewall muscle, and/or bone, and/or major nerve, and/or major vascular structure. Read More

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December 2018

High short-term return to sports rate despite an ongoing healing process after acute meniscus repair in young athletes.

Knee Surg Sports Traumatol Arthrosc 2018 Dec 11. Epub 2018 Dec 11.

Department of Orthopaedic Sports Medicine, Klinikum Rechts der Isar, Technical University Munich, Ismaningerstr. 22, 81675, Munich, Germany.

Purpose: Acute meniscus repair in young athletes is always a challenge due to the long rehabilitation process and time to return to sport (RTS). The purpose was to investigate signal alterations in short-term follow-up after acute meniscus repair on specific magnetic resonance imaging (MRI) scan sequences. It was hypothesized that (1) MRI signal changes over the first postoperative healing phase and represent a continuous healing process and (2) meniscus healing properties correlates with clinical outcomes and RTS. Read More

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December 2018

Large opening gaps, unstable hinge fractures, and osteotomy line below the safe zone cause delayed bone healing after open-wedge high tibial osteotomy.

Knee Surg Sports Traumatol Arthrosc 2018 Dec 11. Epub 2018 Dec 11.

Department of Orthopedic Surgery, Hokuriku Hospital, 2-13-43 Izumigaoka, Kanazawa, 921-8035, Japan.

Purpose: To evaluate bone formation in the osteotomy gap after open-wedge high tibial osteotomy (OWHTO), including after plate removal, and to investigate risk factors for delayed bone healing.

Methods: Ninety-three patients (102 knees) who underwent OWHTO without bone grafting were enrolled. The osteotomy gap was divided into the lateral hinge and the four zones on anteroposterior radiographs, and we defined the zone in which trabecular bone continuity could be observed as gap filling. Read More

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December 2018

Evaluation of age-related differences in anterior cruciate ligament size.

Knee Surg Sports Traumatol Arthrosc 2018 Dec 11. Epub 2018 Dec 11.

Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.

Purpose: The purpose of this study was to reveal the relation between age and the morphological characteristics of the anterior cruciate ligament (ACL) using magnetic resonance imaging (MRI).

Methods: Thirty-seven young subjects who were diagnosed with a meniscus injury without ACL tear using MRI (15 male and 22 female, median age 26, range 15-49), and 33 elderly subjects for whom knee MRI was performed before uni-compartmental knee arthroplasty (11 male and 22 female, median age 77, range 60-83), were included in this study. In the elderly group, healthy ACL gross morphology was confirmed macroscopically during surgery. Read More

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December 2018

Tourniquet application does not affect the periprosthetic bone cement penetration in total knee arthroplasty.

Knee Surg Sports Traumatol Arthrosc 2018 Dec 11. Epub 2018 Dec 11.

Department of Orthopaedics and Trauma Surgery, University Medical Center Mannheim of University Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.

Purpose: Poor scientific evidence exists on the issue of tourniquet application during total knee arthroplasty (TKA). It has been suggested that tourniquet application might improve interdigitation of the cement into the periprosthetic bones due to relatively dry surgical field. The hypothesis of the present study was that tourniquet use did not affect the periprosthetic bone cement penetration. Read More

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December 2018

Novel unilateral C1 double screw and ipsilateral C2 pedicle screw placement combined with contralateral laminar screw-rod fixation for atlantoaxial instability.

Eur Spine J 2018 Dec 11. Epub 2018 Dec 11.

Department of Orthopedics, The Second Affiliated Hospital of Chongqing Medical University, No. 76 Linjiang Road, Yuzhong District, Chongqing, 400010, People's Republic of China.

Purpose: To investigate the anatomical and biomechanical feasibility of the unilateral C1 double screw [pedicle screw (PS) + lateral mass screw (LMS)] and ipsilateral C2 PS combined with contralateral C2 laminar screw (LS)-rod fixation for atlantoaxial instability by comparison with traditional posterior fixation methods.

Methods: Fifteen sets of complete dry bony specimens of atlas were used for morphometric analysis. The working length, width and thickness of the C1 PSs and LMSs were manually measured. Read More

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December 2018

Clinical and radiologic outcomes of two patellar resection techniques during total knee arthroplasty: a prospective randomized controlled study.

Int Orthop 2018 Dec 11. Epub 2018 Dec 11.

Institution of Sports Medicine, Beijing Key Laboratory of Sports Injuries, Peking University Third Hospital, No. 49 North, Garden Road, Haidian, Beijing, 100191, China.

Purpose: A cutting guide technique for patella resurfacing in total knee arthroplasty was expected to result in less patellofemoral syndromes. The aim of this study was to identify differences in the patellofemoral function, clinical outcomes, and radiographic parameters between the freehand and cutting guide patellar resection techniques in patients undergoing total knee arthroplasty.

Methods: A prospective randomized controlled trial was conducted. Read More

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December 2018
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Morphological evaluation of the calcaneofibular ligament in different ankle positions using a three-dimensional MRI sequence.

Surg Radiol Anat 2018 Dec 11. Epub 2018 Dec 11.

Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, 060-8543, Japan.

Purpose: Evaluating images of the lateral ligament of the ankle is not easy, and evaluation of the calcaneofibular ligament (CFL) in particular is difficult. We prospectively conducted morphological measurements of the CFL in different ankle positions and obtain basic data for use in functional assessment of the CFL, diagnosis of CFL injury, and determination of treatment effects.

Methods: The subjects were ten healthy volunteers (ten ankles) with a mean age of 27. Read More

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December 2018

A unique case of an accessory sartorius muscle.

Surg Radiol Anat 2018 Dec 11. Epub 2018 Dec 11.

Department of Anatomy, Keimyung University School of Medicine, 1095 Dalgubeol-daero, Daegu, 704-701, Republic of Korea.

The sartorius muscle (SM) is a long strap muscle originating from the anterior superior iliac spine and inserting onto the medial surface of the proximal tibia. It crosses the anterior compartment of the thigh obliquely and descends towards the medial aspect of the knee. We found an accessory sartorius muscle (ASM) from the inguinal ligament and an original SM bifurcated into medial and lateral heads. Read More

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December 2018

Thermally imprinted microcone structure-assisted lateral-flow immunoassay platforms for detecting disease marker proteins.

Analyst 2018 Dec 12. Epub 2018 Dec 12.

Department of Applied Chemistry and Biotechnology, Graduate School of Engineering, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan.

Although various types of on-site immunoassay platforms have been developed, facile and reliable sample-to-answer immunoassay systems are still under development. In this study, we proposed a lateral-flow immunoassay system utilizing a polymer sheet with microcone array structures fabricated by thermal imprinting. By adding a surfactant to the running/washing buffer, we were able to dispense with complicated chemical modification protocols, which are usually necessary to enhance antibody adsorption. Read More

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December 2018

Lumbar Spine Injuries: Primary Prevention in Amateur and Professional Golf Players.

Sports Med Int Open 2018 Nov 16;2(6):E179-E184. Epub 2018 Nov 16.

Golf Biomechanic Academy, Teaching, Pforzheim, Germany.

In the sport of golf, there is no standard teaching method or swing technique even though golf is known for overuse injuries. This prospective study was to analyze classic swing kinematics in comparison with the Free-Release method and to define a physiological golf swing. Two hundred eighty-three players, age 50-59 years, were included in the study. Read More

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November 2018

A report of human papilloma virus-16 associated vaginal carcinoma after thirty-two years of successful radiation therapy for cervical cancer.

Virusdisease 2018 Dec 3;29(4):537-539. Epub 2018 Aug 3.

1Department of Obstetrics and Gynecology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, 576104 Karnataka India.

Once the recommended 5-year recurrence-free follow-up is achieved for cervical cancers regular annual pelvic examination is mandatory. The main aim of presenting this short report is to emphasize the difficulties in the collection and interpretation of cytology samples from stenosed cervix or vault after pelvic irradiation. Radiotherapy can induce changes in the cellular morphology which may persist for many years. Read More

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December 2018

Orbital compartment syndrome resulting in unilateral blindness in two dogs.

Open Vet J 2018 22;8(4):445-451. Epub 2018 Nov 22.

Department of Clinical Sciences, Companion and Equine Animals, Ophthalmology, University of Liège, Quartier Vallée 2, Avenue de Cureghem 3, 4000 Liège, Belgium.

Orbital compartment syndrome (OCS) is described in humans as an acute rise in intraorbital pressure following a severe and rapidly evolving orbital affection. It includes orbital oedema, haemorrhage or infection causing a marked reduction in local blood perfusion, and severely affecting the orbital neurovascular structures. If not promptly recognised and treated, it results in irreversible blindness. Read More

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November 2018

Bilateral Well Leg Compartment Syndrome Localized in the Anterior and Lateral Compartments following Urologic Surgery in Lithotomy Position.

Case Rep Orthop 2018 14;2018:2328014. Epub 2018 Nov 14.

Department of Orthopedic Surgery, Saiseikai Yokohamashi Tobu Hospital, 3-6-1 Shimosueyoshi, Tsurumi Ward, Yokohama, Kanagawa 230-0012, Japan.

Well leg compartment syndrome (WLCS) is a rare but severe complication after the surgery in lithotomy position. We present a case of bilateral WLCS that occurred after the prolonged urologic surgery in lithotomy position. A 50-year-old man complained of severe bilateral lower leg pain and swelling sixteen hours after the surgery. Read More

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November 2018

3D Reconstruction and Prediction of Sialolith Surgery.

Case Rep Dent 2018 13;2018:3951956. Epub 2018 Nov 13.

Department of Morphology, Faculty of Medicine, Federal University of Ceará, Fortaleza, Brazil.

Imaging examinations play an important role in the diagnosis of sialolithiasis, whose symptoms are initially confounded with other diseases. The objective of the present case report is to highlight imaging and processing techniques as well as image analysis for the preoperative assessment and planning of surgical interventions and adequate treatment of massive sialoliths. A 35-year-old male patient presented complaining of pain in the submandibular region and purulent secretions from a lingual caruncle with slightly increased volume in the region. Read More

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November 2018

The Effect of Periarticular Injection of Methylprednisolone Acetate in Patients with Primary Osteoarthritis of the Proximal Interphalangeal Joints: A Case Controlled Study.

Pain Res Treat 2018 14;2018:7561209. Epub 2018 Nov 14.

Department of Orthopedics, Carmel Medical Center, Haifa, Israel.

Backgrounds: Primary osteoarthritis of the proximal interphalangeal joints (PIPJ) is a common entity. It could be associated with local pain that has no effective treatment. Local subcutaneous periarticular injection of methylprednisolone acetate (MPA) was evaluated in a prospective case-control study. Read More

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November 2018

Traditional Korean Medicine Treatment for Patients with Wilting Disorder: A Literature Review of In Vivo Studies.

Evid Based Complement Alternat Med 2018 13;2018:5601846. Epub 2018 Nov 13.

Department of Acupuncture & Moxibustion, Kyung Hee University Hospital at Gangdong, 149 Sangil-dong, Gangdong-gu, Seoul 134-727, Republic of Korea.

Wilting disorder is an abnormal condition characterized by weakness and paralysis of the upper and lower extremities. Pathogenesis and treatment target of the disorder are unclear; hence, allopathic treatment is generally used to relieve the symptoms. To investigate the treatment mechanism and effect of Traditional Korean Medicine (TKM) in patients with wilting disorder, we reviewed in vivo studies that focused on the effect of TKM on the main symptoms of wilting disorder and treatment of the diseases that can cause these symptoms. Read More

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November 2018

Ancestrality and Mosaicism of Giant Viruses Supporting the Definition of the Fourth TRUC of Microbes.

Front Microbiol 2018 27;9:2668. Epub 2018 Nov 27.

Aix-Marseille Université, Institut de Recherche pour le Développement (IRD), Assistance Publique - Hôpitaux de Marseille (AP-HM); Microbes, Evolution, Phylogeny and Infection (MEΦI); Institut Hospitalo-Universitaire (IHU) - Méditerranée Infection, Marseille, France.

Giant viruses of amoebae were discovered in 2003. Since then, their diversity has greatly expanded. They were suggested to form a fourth branch of life, collectively named 'TRUC' (for "Things Resisting Uncompleted Classifications") alongside , , and . Read More

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November 2018

Margin Status and Duration of Surgery in Resection of Tongue Carcinoma with Ultrasound Coagulation Device: a Comparative Study.

Indian J Surg Oncol 2018 Dec 20;9(4):501-504. Epub 2018 Jul 20.

Department of Otolaryngology and Head Neck Surgery, Grant Medical College and Sir JJ Group of Hospitals, Mumbai, India.

Tongue is one of the most common subsites involved by oral cancer. Improved surgical care and adjuvant therapy, along with better rehabilitation has significantly improved long-term survival and quality of life in patients with oral cancer. Primary surgical treatment is the preferred modality of treatment in cancers of the oral tongue. Read More

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December 2018

Investigation on spp. eggs in hair coat of dogs in YSR Kadapa district of Andhra Pradesh, India.

J Parasit Dis 2018 Dec 15;42(4):550-553. Epub 2018 Oct 15.

2Department of Veterinary Clinical Complex, College of Veterinary Science, Faculty of Veterinary Medicine, Sri Venkateswara Veterinary University, Proddatur, Andhra Pradesh 516 360 India.

Present study was aimed to record the spp. eggs in dog's hair and to analyze the incidence in breed and age wise along with incidence variations in the anatomical locations of hair over the body. Dogs presented to the hospital were screened for enteric parasitic ova and hair samples were collected from the different body regions including head and neck region, ventral and lateral abdomen, perianal and hindquarters and tail region. Read More

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December 2018

T2-relaxation mapping and fat fraction assessment to objectively quantify clinical activity in thyroid eye disease: an initial feasibility study.

Eye (Lond) 2018 Dec 11. Epub 2018 Dec 11.

Department of Ophthalmology, Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Cambridge, UK.

Imaging in thyroid eye disease (TED) is used to exclude other diagnoses, assess for apical crowding and plan surgery. But to quantify TED activity objectively, subjective clinical scoring assessments remain the norm. Magnetic resonance imaging (MRI) T2-relaxation times correlate with extra-ocular muscle (EOM) inflammation, but are confounded by signal from fat. Read More

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December 2018

The Protozoan Targets Bacteria with Laterally Acquired NlpC/P60 Peptidoglycan Hydrolases.

MBio 2018 Dec 11;9(6). Epub 2018 Dec 11.

School of Biological Sciences, University of Auckland, Auckland, New Zealand

The human eukaryotic pathogen causes trichomoniasis, a prevalent sexually transmitted infection. This extracellular protozoan is intimately associated with the human vaginal mucosa and microbiota, but key aspects of the complex interactions between the parasite and the vaginal bacteria remain elusive. We report that has acquired, by lateral gene transfer from bacteria, genes encoding peptidoglycan hydrolases of the NlpC/P60 family. Read More

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December 2018

Sexuality and intimacy in ALS: systematic literature review and future perspectives.

J Neurol Neurosurg Psychiatry 2018 Dec 11. Epub 2018 Dec 11.

Department of Neurology and Laboratory of Neuroscience, Istituto Auxologico Italiano, IRCCS, Milan, Italy

Several features of amyotrophic lateral sclerosis (ALS) impact on sexuality and intimate relationship; however, the issue has received poor attention so far. We performed a systematic literature review in order to provide an up-to-date account of sexuality in ALS. References were identified by searches of PubMed, Web of Science, Scopus and PsycINFO (1970-2017, English literature). Read More

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December 2018