3,595 results match your criteria Lasers in Surgery and Medicine [Journal]


Society Update.

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Lasers Surg Med 2019 Feb;51(2):208-209

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http://dx.doi.org/10.1002/lsm.22963DOI Listing
February 2019

American Society for Laser Medicine and Surgery Abstracts.

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Lasers Surg Med 2019 Feb;51(S30):S4-S59

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http://doi.wiley.com/10.1002/lsm.23059
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http://dx.doi.org/10.1002/lsm.23059DOI Listing
February 2019
1 Read

Stereotaxic laser brain surgery with 1940-nm Tm:fiber laser: An in vivo study.

Lasers Surg Med 2019 Feb 19. Epub 2019 Feb 19.

Biophotonics Laboratory, Institute of Biomedical Engineering, Bogazici University, Kandilli Campus, Cengelkoy, Istanbul, 34684, Turkey.

Background: With exciting developments in fiber laser technology, studies investigating the use of lasers in neurosurgery have been increasing in the recent years. Fiber lasers are advantageous in many ways; first of all they are compact and they provide a more comfortable environment in the operating room due to feasibility of coupling laser light to different cross-sectioned fibers. Thulium fiber (Tm:fiber) lasers have been under investigation for medical applications since 2005 due to their spectral proximity to the water absorption peak. Read More

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http://dx.doi.org/10.1002/lsm.23070DOI Listing
February 2019

Vascular-targeted low dose photodynamic therapy stabilizes tumor vessels by modulating pericyte contractility.

Lasers Surg Med 2019 Feb 19. Epub 2019 Feb 19.

Department of Thoracic Surgery, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.

Vascular-targeted low-dose photodynamic therapy (L-PDT) was shown to improve chemotherapy distribution in malignant pleural tumors such as malignant pleural mesothelioma (MPM). However, the mechanisms triggered by L-PDT on the tumor vasculature are still debated. In pericyte and endothelial cell co-cultures, we show that pericytes exhibit enhanced sensitivity towards L-PDT compared to endothelial cells, displaying actin stress fibers and cellular contraction via Rho/ROCK kinase signaling myosin light chain and focal adhesion kinase phosphorylation (MLC-P, FAK-P). Read More

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http://dx.doi.org/10.1002/lsm.23069DOI Listing
February 2019

Efficacy of fractional CO laser in the treatment of genitourinary syndrome of menopause in Latin-American Population: First Peruvian experience.

Lasers Surg Med 2019 Feb 19. Epub 2019 Feb 19.

Universidad Del Valle, Cali, Colombia.

Objective: This PUBA study aimed to assess the efficacy of fractional CO2 laser in the treatment of genitourinary syndrome of menopause (GSM).

Methods: GSM symptoms were assessed before, 1 month after the first session and 1 month after the third session of laser (3 sessions with a 30 days interval between them) in 60 women (median, interquartile range: 55, 49-69). Subjective (visual analog scale) and objective (Vaginal Health Index, VHIS; Vaginal Maturity Index/Frost Index; Spanish Overactive Bladder Questionnaire-Short Form, USMEX Spanish OAB-qSF and Female Sexual Function Index, FSFI) measures were used during the study period to assess CO2 fractionated laser treatment outcomes compared to baseline. Read More

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http://doi.wiley.com/10.1002/lsm.23066
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http://dx.doi.org/10.1002/lsm.23066DOI Listing
February 2019
5 Reads

Sound levels and safety in cosmetic laser surgery.

Lasers Surg Med 2019 Feb 1. Epub 2019 Feb 1.

SkinCare Physicians, 1244 Boylston Street, Suite 103, Chestnut Hill, Massachusetts, 02467.

Objectives: Measure the sound levels produced by various lasers commonly used during routine outpatient cosmetic surgery to determine whether or not their use exceeds exposure levels set forth by the US National Institute for Occupational Safety and Health (NIOSH) and the US Occupational Safety and Health Administration (OSHA).

Materials And Methods: Using two different meters, the sound levels of lasers commonly used in cosmetic surgery were recorded during various procedures for several indications: tattoo removal, treatment of lentigines and pigmented lesions, facial erythema and vascular lesions, hair removal and resurfacing of acne scars, and photoaging.

Results: All but five lasers had a maximum sound level below 85 dBA, the limit proposed by NIOSH. Read More

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http://dx.doi.org/10.1002/lsm.23062DOI Listing
February 2019
2 Reads

Needle-free pneumatic injection device; histologic assessment using a rat model and parameter comparison in predicting collagen synthesis degree.

Lasers Surg Med 2019 Feb 1. Epub 2019 Feb 1.

Department of Dermatology, Korea University Ansan Hospital, 123 Jeokgeum-ro, Danwon-gu, Ansan-si, Gyeonggi-do, Korea.

Background: Needle-free pneumatic injections have been recently introduced to the field of dermatology to inject such substances as hyaluronic acid. However, data on the influence of various pneumatic injection parameters on collagen synthesis are lacking.

Objective: Compare the effect of diameter, pressure, and volume of a pneumatic injection jet on collagen synthesis and fluid dispersion pattern using a rat model. Read More

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http://dx.doi.org/10.1002/lsm.23046DOI Listing
February 2019

Photobiomodulation with polychromatic light increases zone 4 survival of transverse rectus abdominis musculocutaneous flap.

Lasers Surg Med 2019 Feb 1. Epub 2019 Feb 1.

Department of Plastic Reconstructive and Aesthetic Surgery, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Objective: The aim of this study was to evaluate the effect of relatively novel approach of application of polychromatic light waves on flap survival of experimental musculocutaneous flap model and to investigate efficacy of this modality as a delay procedure to increase vascularization of zone 4 of transverse rectus abdominis musculocutaneous (TRAM) flap.

Methods: Twenty-one Wistar rats were randomized and divided into 3 experimental groups (n = 7 each). In group 1 (control group), after being raised, the TRAM flap was sutured back to its bed without any further intervention. Read More

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http://doi.wiley.com/10.1002/lsm.23063
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http://dx.doi.org/10.1002/lsm.23063DOI Listing
February 2019
4 Reads

Light-based home-use devices for hair removal: Why do they work and how effective they are?

Lasers Surg Med 2019 Jan 25. Epub 2019 Jan 25.

Skinperium, Luxembourg, Europe.

Objectives: This review has the following objectives: Firstly, it provides an explanation of the evolution of laser/intense pulsed light (IPL) hair reduction modalities from high fluence professional devices to low fluence home-use appliances. Secondly, it summarises published literature reviews on home-use devices (HUDs) as evidence of their growing credibility. Thirdly, it proposes mechanistic differences in light delivery regimes and the resulting divergences in mode of action. Read More

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http://dx.doi.org/10.1002/lsm.23061DOI Listing
January 2019
4 Reads

Computational analysis of six optical coherence tomography systems for vocal fold imaging: A comparison study.

Lasers Surg Med 2019 Jan 25. Epub 2019 Jan 25.

Beckman Laser Institute & Medical Clinic, University of California-Irvine, Irvine, California, 92612.

Objectives: There have been many advancements in laryngeal imaging using optical coherence tomography (OCT), with varying system design and probes for use in research, office, and operating room settings. We evaluated the performance of six distinct OCT systems in imaging porcine vocal folds (cords) using computational image processing and segmentation.

Methods: Porcine vocal folds were scanned using six OCT systems. Read More

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http://dx.doi.org/10.1002/lsm.23060DOI Listing
January 2019

Comparison of 311-nm Titanium:Sapphire laser and 308-nm excimer laser treatment for vitiligo: A randomized controlled non-inferiority trial.

Lasers Surg Med 2019 Jan 25. Epub 2019 Jan 25.

Department of Dermatology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.

Objectives: The 308-nm excimer laser (EL) has been widely used for localized vitiligo. The recently developed Titanium:Sapphire laser, emits a wavelength of 311 nm, would be expected to be as effective as excimer laser in treatment of vitiligo but few controlled trials have been reported. We sought to compare the efficacy and safety of the TSL and EL as vitiligo treatments. Read More

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http://dx.doi.org/10.1002/lsm.23048DOI Listing
January 2019

Efficacy and safety of intense pulsed light with a KTP filter for the treatment of solar lentigines.

Lasers Surg Med 2019 Jan 25. Epub 2019 Jan 25.

The Pearl Dermatology, Houston, Texas.

Background: Optical energy-based devices, including intense pulsed light (IPL) and potassium titanyl phosphate (KTP) lasers achieve reduction of pigmented and vascular lesions in a relatively similar number of treatments. This study aimed to evaluate the efficacy and safety of an IPL with a "KTP-like" filter emitting a wavelength of 525-585 nm for the treatment of solar lentigines on the hands and face.

Methods: This was a single center, prospective, open-label clinical trial including 16 healthy Caucasian subjects (15 females, mean age, 55 years; skin types II and III) with hand and facial solar lentigines. Read More

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http://dx.doi.org/10.1002/lsm.23056DOI Listing
January 2019
1 Read

Patient satisfaction and our clinical experience with 459 microfocused ultrasound treatments.

Lasers Surg Med 2019 Jan 21. Epub 2019 Jan 21.

Union Square Laser Dermatology, 19 Union Square West, 5th Floor, New York, New York.

Purpose: Microfocused ultrasound (MFUS) is a safe and effective method for noninvasive skin tightening. Previous clinical studies demonstrate a 60-100% patient satisfaction after MFUS. We used an anonymous online platform after MFUS to assess patient satisfaction. Read More

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http://dx.doi.org/10.1002/lsm.23058DOI Listing
January 2019
2 Reads

Hyperspectral imaging in automated digital dermoscopy screening for melanoma.

Lasers Surg Med 2019 Jan 17. Epub 2019 Jan 17.

Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York.

Objectives: Early melanoma detection decreases morbidity and mortality. Early detection classically involves dermoscopy to identify suspicious lesions for which biopsy is indicated. Biopsy and histological examination then diagnose benign nevi, atypical nevi, or cancerous growths. Read More

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http://doi.wiley.com/10.1002/lsm.23055
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http://dx.doi.org/10.1002/lsm.23055DOI Listing
January 2019
30 Reads

Society Update.

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Lasers Surg Med 2019 Jan;51(1):114-115

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http://dx.doi.org/10.1002/lsm.22959DOI Listing
January 2019

High power holmium:YAG versus thulium fiber laser treatment of kidney stones in dusting mode: ablation rate and fragment size studies.

Lasers Surg Med 2019 Jan 16. Epub 2019 Jan 16.

Department of Physics and Optical Science, University of North Carolina at Charlotte, Charlotte, North Carolina.

Objectives: The experimental Thulium fiber laser (TFL) is currently being studied as a potential alternative to the gold standard Holmium:YAG laser for lithotripsy. Recent advances in both Holmium and TFL technology allow operation at similar laser parameters for direct comparison. The use of a "dusting" mode with low pulse energy (0. Read More

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http://dx.doi.org/10.1002/lsm.23057DOI Listing
January 2019

Improved MR thermometry for laser interstitial thermotherapy.

Lasers Surg Med 2019 Jan 15. Epub 2019 Jan 15.

Utah Center for Advanced Imaging Research, Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, Utah.

Objectives: To develop, test and evaluate improved 2D and 3D protocols for proton resonance frequency shift magnetic resonance temperature imaging (MRTI) of laser interstitial thermal therapy (LITT). The objective was to develop improved MRTI protocols in terms of temperature measurement precision and volume coverage compared to the 2D MRTI protocol currently used with a commercially available LITT system.

Methods: Four different 2D protocols and four different 3D protocols were investigated. Read More

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http://dx.doi.org/10.1002/lsm.23049DOI Listing
January 2019

Comparison of an Er: YAG laser osteotome versus a conventional drill for the use in osteo- odonto-keratoprosthesis (OOKP).

Lasers Surg Med 2019 Jan 15. Epub 2019 Jan 15.

Department of Ophthalmology, University Hospital Basel, University Basel, Basel, Switzerland.

Objectives: The osteo-odonto-kerato-prosthesis (OOKP) procedure is a complex, multi-stage, multidisciplinary surgical intervention for the treatment of severe corneal blindness. One step of the OOKP consists of creating a precise hole into a tooth in which an optic cylinder is subsequently inserted; its shape must ensure a perfect watertight fit. The Er: YAG laser (L) used in this study is part of CARLO®, the first laser osteotome that enables surgical planning based on computed tomography data, robot guidance, and a precise execution of laser cuts in teeth and bone tissue, using laser photoablation rather than conventional mechanical methods. Read More

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http://dx.doi.org/10.1002/lsm.23053DOI Listing
January 2019

Decreased phototoxicity of photodynamic therapy by Cx32/Cx26-composed GJIC: A "Good Samaritan" effect.

Lasers Surg Med 2019 Jan 7. Epub 2019 Jan 7.

Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Pharmacy School of Xuzhou Medical University, Xuzhou City 221004, Jiangsu Province, P. R. China.

Background And Objective: Photodynamic therapy (PDT) has been widely used to treat malignant tumors. Our previous studies indicated that connexin (Cx) 32- and Cx26-composed gap junctional intercellular communication (GJIC) could improve the phototoxicity of PDT. However, the role of heterotypic Cx32/Cx26-formed GJIC in PDT phototoxicity is still unknown. Read More

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http://dx.doi.org/10.1002/lsm.23044DOI Listing
January 2019
2 Reads

A miniaturized, tethered, spectrally-encoded confocal endomicroscopy capsule.

Lasers Surg Med 2019 Jan 6. Epub 2019 Jan 6.

Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, 02114, Massachusetts.

Background And Objective: The tethered spectrally-encoded confocal endomicroscopy (SECM) capsule is an imaging device that once swallowed by an unsedated patient can visualize cellular morphologic changes associated with gastrointestinal (GI) tract diseases in vivo. Recently, we demonstrated a tethered SECM capsule for counting esophageal eosinophils in patients with eosinophilic esophagitis (EoE) in vivo. Yet, the current tethered SECM capsule is far too long to be widely utilized for imaging pediatric patients, who constitute a major portion of the EoE patient population. Read More

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http://dx.doi.org/10.1002/lsm.23050DOI Listing
January 2019
2 Reads

Treatment of telangiectasia on the cheeks with a compact yellow (585 nm) semiconductor laser and a green (532 nm) KTP laser: a randomized double-blinded split-face trial.

Lasers Surg Med 2019 Jan 6. Epub 2019 Jan 6.

Optoelectronics Research Centre, Tampere University of Technology (TUT), Korkeakoulunkatu 3, 33720, Tampere, Finland.

Objectives: The primary objective of this study was to compare a traditional green KTP laser to a new investigational yellow laser (PhotoLase) in the treatment of facial telangiectasia in terms of the treatment outcomes. The secondary objective was to assess the functionality and reliability of the PhotoLase system from the perspective of the user.

Study Design/methods: The study was a randomized split-face double-blinded study that compared the treatment efficacy of the 532-nm KTP laser and the investigational 585-nm PhotoLase laser. Read More

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http://dx.doi.org/10.1002/lsm.23051DOI Listing
January 2019

Comparison between topical recombinant human epidermal growth factor and Aloe vera gel in combination with ablative fractional carbon dioxide laser as treatment for striae alba: A randomized double-blind trial.

Lasers Surg Med 2019 Jan 6. Epub 2019 Jan 6.

Department of Pathology and Forensic Medicine, Thammasat University, Pathumthani, Thailand.

Objectives: Striae distensae are linear atrophic dermal scars. Despite several currently available therapeutic modalities, no consistently effective therapies have been established. This study aimed to evaluate and compare the efficacy of topical recombinant human epidermal growth factor (rhEGF) and ablative fractional carbon dioxide (CO ) laser (AFXL) versus ablative fractional CO laser and topical Aloe vera gel in treating striae alba. Read More

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http://dx.doi.org/10.1002/lsm.23052DOI Listing
January 2019
1 Read

Eradication of hairy mouth after oncological resection of the tongue and floor mouth using a diode laser 808 nm. Postoperative pain assessment using thermal infrared imaging.

Lasers Surg Med 2019 Jan 6. Epub 2019 Jan 6.

Department of Morphology, Experimental Medicine and Surgery, University of Ferrara, Ferrara, Italy.

Objectives: Vascularized soft tissue flaps are often harvested from hair-bearing areas, such as the radial forearm or anterolateral thigh, making their use in oral reconstruction problematic due to postoperative hair growth. The presence of intact hair follicles in free tissue transfer and continued hair growth at the recipient site can result in difficulties with oral hygiene, intraoral irritation, food trapping, and patient distress. This study was to evaluate the intraoral efficacy and safety of a diode laser 808 nm when used for hair removal. Read More

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http://doi.wiley.com/10.1002/lsm.23054
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http://dx.doi.org/10.1002/lsm.23054DOI Listing
January 2019
1 Read
2.619 Impact Factor

MR-guided laser interstitial thermal therapy in the treatment of recurrent intracranial meningiomas.

Lasers Surg Med 2018 Dec 28. Epub 2018 Dec 28.

Department of Neurosurgery, Henry Ford Hospital, 2799 West Grand Blvd, Detroit 48202, Michigan.

Objective: Recurrent meningiomas can prove problematic for treatment, especially if anaplastic, as options are limited primarily to surgery and radiation therapy. Laser interstitial thermal therapy (LITT) is a minimally invasive technique for achieving immediate cytoreduction. This study seeks to determine the utility of LITT in the setting of recurrent meningiomas. Read More

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http://dx.doi.org/10.1002/lsm.23045DOI Listing
December 2018
1 Read

Transdermal delivery of water-soluble fluorescent antibody mediated by fractional Er:YAG laser for the diagnosis of lupus erythematosus in mice.

Lasers Surg Med 2018 Dec 28. Epub 2018 Dec 28.

Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (HUST), Wuhan 430022, China.

Objectives: Although transdermal drug delivery system (TDDS) has been successfully used for delivering small molecules, its application in the delivery of diagnostic antibodies has been limited due to their large size. In this study, we aim to obtain a broad insight in the dynamics of TRITC-conjugated Goat Anti-Mouse IgG (T-IgG) uptake in fractional Er:YAG laser pretreated skin and provide a new technical option for detecting lupus erythematosus (LE) in mice.

Methods: The skins of SD and MRL/lpr mice were treated by fractional Er:YAG laser followed by external application of T-IgG. Read More

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http://doi.wiley.com/10.1002/lsm.23047
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http://dx.doi.org/10.1002/lsm.23047DOI Listing
December 2018
10 Reads

The ablative fractional coagulation zone influences skin fluorescence intensities of topically applied test molecules-An in vitro study with fluorescence microscopy and fluorescence confocal microscopy.

Lasers Surg Med 2019 Jan 25;51(1):68-78. Epub 2018 Dec 25.

Department of Dermatology, University of Copenhagen, Bispebjerg Hospital, 2400, Copenhagen NV, Denmark.

Background: Ablative fractional laser (AFL) increases uptake of topically applied skin agents. The coagulation zone (CZ) surrounding vertically ablated channels may influence uptake of drugs.

Objectives: To investigate impact of CZ thickness on skin fluorescence intensities (FI) of a hydrophilic molecule by means of fluorescence microscopy (FM) and fluorescence confocal microscopy (FCM). Read More

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http://dx.doi.org/10.1002/lsm.23034DOI Listing
January 2019

Efficacy of noninvasive multisource radiofrequency treatment on periorbital rhytids using an imaging device.

Lasers Surg Med 2018 Dec 21. Epub 2018 Dec 21.

Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.

Objective: To evaluate the efficacy of the multisource radiofrequency in periorbital wrinkles treatment using a VISIA imager.

Methods: This is a prospective cohort study involving 30 sites in 15 patients.

Inclusion Criteria: healthy subjects with periorbital wrinkles. Read More

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http://doi.wiley.com/10.1002/lsm.23038
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http://dx.doi.org/10.1002/lsm.23038DOI Listing
December 2018
3 Reads

Discrimination of cancerous and healthy colon tissues: A new laser-based method.

Lasers Surg Med 2018 Dec 21. Epub 2018 Dec 21.

Faculty of Science, Department of Physics, University of Selçuk, Selçuklu, Konya, 42031, Turkey.

Background: Femtosecond (fs) Laser Ionisation Mass Spectrometry (fs-LIMS) on colon tissues are described and investigated using ionization/fragmentation processes in details to present a new application in this study. Linear Time of Flight (L-TOF) mass analyzer was utilized to investigate paraffin-embedded human tissue in this study. The effect of fs laser intensity on the spectral characteristics was investigated and interpreted due to mass spectra obtained using 800 nm wavelength with 90 fs pulses at 1 kHz repetition rate. Read More

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http://dx.doi.org/10.1002/lsm.23033DOI Listing
December 2018
2 Reads

Impact of photodynamic therapy versus ultrasonic scaler on gingival health during treatment with orthodontic fixed appliances.

Lasers Surg Med 2018 Dec 21. Epub 2018 Dec 21.

Complutense University of Madrid, School of Dentistry, Stomatology IV Department, Plaza Ramón y Cajal sn, 28040, Madrid, Spain.

Objectives: Poor oral hygiene during treatment with fixed appliances results in plaque accumulation. The presence of bacteria in the gingival crevice triggers an inflammatory reaction in the gingival tissues. The aim of this study was to compare the impact of two preventive treatments, photodynamic therapy (PDT), and ultrasonic scaler (US), on gingival health in patients under fixed orthodontic treatment. Read More

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http://dx.doi.org/10.1002/lsm.23035DOI Listing
December 2018
1 Read

Science and peace.

Authors:
Kristen M Kelly

Lasers Surg Med 2019 Jan 18;51(1):5-7. Epub 2018 Dec 18.

Beckman Laser Institute, University of California, Irvine, California 92697.

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http://dx.doi.org/10.1002/lsm.23043DOI Listing
January 2019

Retraction statement: Dental hard tissue ablation using mid-infrared tunable nanosecond pulsed Cr:CdSe laser.

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Lasers Surg Med 2018 Dec 19;50(10):1052. Epub 2018 Nov 19.

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http://dx.doi.org/10.1002/lsm.23040DOI Listing
December 2018

Society Update.

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Lasers Surg Med 2018 Dec;50(10):1050-1051

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http://dx.doi.org/10.1002/lsm.22733DOI Listing
December 2018

Induction of fat apoptosis by a non-thermal device: Mechanism of action of non-invasive high-intensity electromagnetic technology in a porcine model.

Lasers Surg Med 2019 Jan 14;51(1):47-53. Epub 2018 Dec 14.

Veterinary Research Institute, Brno, Czech Republic.

Objectives: While controlled thermal changes in subcutaneous tissue have been used to trigger apoptosis of fat cells and have been proven clinically efficacious, another mechanism of electromagnetic stress suggests that fat apoptosis could be achieved by a non-thermal manner as well. This animal model study investigates the use of a non-invasive high-intensity magnetic field device to induce apoptosis in fat cells.

Methods: Yorkshire pigs (N = 2) received one treatment (30 minutes) in the abdominal area using a High-Intensity Focused Electromagnetic (HIFEM) device. Read More

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http://dx.doi.org/10.1002/lsm.23039DOI Listing
January 2019
2 Reads

Outcomes of long-pulsed 1064 nm Nd:YAG laser treatment of basal cell carcinoma: A retrospective review.

Lasers Surg Med 2019 Jan 3;51(1):34-39. Epub 2018 Dec 3.

Department of Dermatology, University of California, San Diego School of Medicine, 9500 Gillman Drive, La Jolla, California, 92093.

Background And Objective: Recent prospective trials have supported treatment of nonfacial BCC with long-pulsed 1064 nm Nd:YAG laser based on short-term histologic clearance rates. Studies have yet to identify the long-term clinical clearance rates of this specific laser therapy for BCC.

Study Design/material And Methods: This is a retrospective review of BCC treated with long-pulsed 1064 nm Nd:YAG laser, which have been clinically monitored for at least 6 months, to assess for recurrence and cosmetic outcomes of the treated area. Read More

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http://dx.doi.org/10.1002/lsm.23041DOI Listing
January 2019
1 Read

Treatment of poikiloderma of Civatte using a redesigned pulsed dye laser with a 15 mm diameter treatment spot.

Lasers Surg Med 2019 Jan 27;51(1):54-58. Epub 2018 Nov 27.

Syneron-Candela Corporation, Wayland, Massachusetts.

Objectives: The pulsed-dye laser has long been a gold standard in the treatment of poikiloderma of Civatte. Recent advances in pulsed dye laser technology enable output energies 50% higher, enabling beam diameters of up to 15 mm with clinically relevant fluences. In this study, we investigate this new laser for treatment of this condition. Read More

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http://doi.wiley.com/10.1002/lsm.23036
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http://dx.doi.org/10.1002/lsm.23036DOI Listing
January 2019
20 Reads

Clinical benefit of using a multifractional Er:YAG laser combined with a spatially modulated ablative (SMA) module for the treatment of striae distensae: A prospective pilot study in 20 patients.

Lasers Surg Med 2018 Nov 27. Epub 2018 Nov 27.

Department of Plastic, Reconstructive and Maxillo facial Surgery, Hopital Henri Mondor, Creteil, 94010, France.

Background And Objective: Striae distensae (SD) are cutaneous lesions that often occur on the breasts, abdomen, hips, and thighs. The aim of this study is to evaluate the effectiveness of a new technique using a non-invasive Er:YAG laser combined with Spatially Modulated Ablation (SMA) module for the treatment of SD.

Study Design/materials And Methods: This prospective pilot clinical study included 20 patients with skin phototypes I to IV who are affected by SD. Read More

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http://doi.wiley.com/10.1002/lsm.23042
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http://dx.doi.org/10.1002/lsm.23042DOI Listing
November 2018
13 Reads
2.619 Impact Factor

Treatment of benign pigmented lesions using a novel Dermal Cooling System.

Lasers Surg Med 2019 Jan 27;51(1):59-61. Epub 2018 Nov 27.

Department of Dermatology, University of California San Diego, La Jolla 92122, California.

Benign pigmented lesions are among the most common dermatologic diagnoses that patients seek treatments for. Treatment modalities range from cryotherapy to light and laser-based technologies. These treatments have been shown to be effective, yet may lead to dyschromia or significant downtime. Read More

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http://dx.doi.org/10.1002/lsm.23037DOI Listing
January 2019
1 Read

Soft tissue cutting efficiency by 980 nm laser with carbon-, erbium-, and titanium-doped optothermal fiber converters.

Lasers Surg Med 2019 Feb 15;51(2):185-200. Epub 2018 Nov 15.

ITMO University, Saint-Petersburg, Russian Federation.

Objectives: The use of near-IR diode lasers for contact soft tissue surgery is attended by a risk of severe thermal damage of surrounding tissues due to the low cutting efficiency of these lasers. To increase the cutting efficiency of a near-IR lasers in contact surgery special tips (converters) which transform laser light to heat are used. The present in vivo study evaluated temperature dynamics and soft tissue cutting efficiency of 980 nm diode laser equipped with standard carbon- and novel erbium- and titanium-doped converters. Read More

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http://doi.wiley.com/10.1002/lsm.23006
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http://dx.doi.org/10.1002/lsm.23006DOI Listing
February 2019
9 Reads

Assessment of combined fractional CO and tranexamic acid in melasma treatment.

Lasers Surg Med 2019 Jan 15;51(1):27-33. Epub 2018 Nov 15.

Dermatology Department, Cairo University Kasr Alainy Faculty of Medicine, Cairo, Egypt.

Background: Melasma continues to be a disease that is difficult to treat with no fully satisfactory results. The role of a fractional CO laser in its treatment is controversial. The addition of tranexamic acid (TXA) might be helpful. Read More

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http://doi.wiley.com/10.1002/lsm.23032
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http://dx.doi.org/10.1002/lsm.23032DOI Listing
January 2019
14 Reads

Energy-based treatment for gynecologic conditions including genitourinary syndrome of menopause: Consensus, controversies, recommendations, and FDA clearance.

Lasers Surg Med 2018 Nov 8. Epub 2018 Nov 8.

Department of Gynecology, Uroclinica, Mendoza, Argentina Department of Laser Surgery, Palmares Hospital, Mendoza, Argentina.

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http://doi.wiley.com/10.1002/lsm.23031
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http://dx.doi.org/10.1002/lsm.23031DOI Listing
November 2018
7 Reads

Comparison of treatment options for small to medium congenital melanocytic nevi: A retrospective review of 119 cases.

Lasers Surg Med 2019 Jan 30;51(1):62-67. Epub 2018 Oct 30.

Department of Dermatology, Gangnam Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.

Objectives: For small to medium sized congenital melanocytic nevi (CMN), the treatment of choice is staged surgical excision. Ablative lasers or pigment-specific lasers have also been recommended for lesions difficult for surgical removal or to avoid surgery. In this study, we retrospectively analyzed the results of several treatment options for CMN to find out the optimal treatment method. Read More

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http://doi.wiley.com/10.1002/lsm.23030
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http://dx.doi.org/10.1002/lsm.23030DOI Listing
January 2019
5 Reads

Setting appropriate pain expectations: Lessons learned from a clinical trial.

Lasers Surg Med 2018 Oct 30. Epub 2018 Oct 30.

SkinCare Physicians, 1244 Boylston Street, Chestnut Hill, 02467, Massachusetts.

Objective: This retrospective study compares subject-reported pain levels and expectations set forth by industry and treating physicians during a clinical trial of an energy based device. The physiologic and emotional aspects of pain expectations are discussed and recommendations are made for strategic patient counseling.

Materials And Methods: Average and mode pain scores were collected from the records of a previously conducted clinical trial investigating a radiofrequency microneedling device at three different settings. Read More

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http://dx.doi.org/10.1002/lsm.23029DOI Listing
October 2018

Evaluation of the safety and efficacy of the dual wavelength picosecond laser for the treatment of benign pigmented lesions in Asians.

Lasers Surg Med 2019 Jan 25;51(1):14-22. Epub 2018 Oct 25.

Division of Dermatology, Department of Medicine, The University of Hong Kong, Hong Kong SAR, China.

Background And Objectives: Cutaneous pigmentary disorders are both more common and more difficult to treat in patients with skin color given the higher melanin content in the epidermis. Although Q-switched lasers are widely considered to be the standard treatment for both epidermal and dermal pigmentary conditions, a very high risk of post-inflammatory hyperpigmentation (PIH) of up to 25% is seen in patients with skin of color. Recently, the novel picosecond laser with pulse durations operating at sub-nanosecond domains has been shown to be effective in tattoo removal and in the treatment of acne scars. Read More

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http://doi.wiley.com/10.1002/lsm.23028
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http://dx.doi.org/10.1002/lsm.23028DOI Listing
January 2019
27 Reads

Using reflectance confocal microscopy to observe in vivo melanolysis after treatment with the picosecond alexandrite laser and Q-switched Nd:YAG laser in melasma.

Lasers Surg Med 2018 Oct 23. Epub 2018 Oct 23.

Department of Dermatology, School of Medicine, Kyung Hee University, Seoul, Korea.

Objectives: Melasma is an acquired type of hyperpigmentation that is characterized by the appearance of scattered light- to dark-brown macules and patches on the face. Recently, several lasers have been proposed as treatment options for melasma. In particular, the picosecond alexandrite laser is an ideal laser for selective photothermal melanolysis. Read More

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http://dx.doi.org/10.1002/lsm.23025DOI Listing
October 2018
2 Reads

Society Update.

Authors:

Lasers Surg Med 2018 Sep;50(9):973-974

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http://dx.doi.org/10.1002/lsm.22731DOI Listing
September 2018

Lidocaine-induced potentiation of thermal damage in skin and carcinoma cells.

Lasers Surg Med 2019 Jan 15;51(1):88-94. Epub 2018 Oct 15.

Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts.

Objective: Lidocaine acts as a local anesthetic by blocking transmembrane sodium channel permeability, but also induces the synthesis of heat shock proteins and sensitizes cells to hyperthermia. A previous study reported two cases of deep focal skin ulceration at points corresponding to depot local lidocaine injection sites after treatment with non-ablative fractional resurfacing and it was hypothesized that lidocaine had focally sensitized keratinocytes to the thermal damage of laser treatment. The objective of this study was to investigate whether lidocaine potentiates hyperthermia damage to both normal and cancerous skin cells using an in vitro model. Read More

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http://dx.doi.org/10.1002/lsm.23027DOI Listing
January 2019
2 Reads

Long pulsed dye laser with a back-to-back double-pulse technique and compression for the treatment of epidermal pigmented lesions.

Lasers Surg Med 2019 Feb 15;51(2):136-140. Epub 2018 Oct 15.

Department of Dermatology, Northwestern University Feinberg School of Medicine, 676 N. St. Clair Street, Suite 1600, Chicago 60611, Illinois.

Background: In the recent past, long pulsed dye lasers (LPDL) have been investigated for the treatment of epidermal pigmented lesions (EPLs). Using a pigmented lesion compression headpiece, blood is pushed laterally out of the laser field focusing laser energy on melanin. Recent studies have demonstrated excellent responses using a single-pulse at the following settings: 9-12 J/cm , 1. Read More

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http://doi.wiley.com/10.1002/lsm.23009
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http://dx.doi.org/10.1002/lsm.23009DOI Listing
February 2019
13 Reads

The toxic edge-A novel treatment for refractory erythema and flushing of rosacea.

Lasers Surg Med 2018 Oct 12. Epub 2018 Oct 12.

Department of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Purpose: Rosacea is a common, chronic facial skin disease that affects the quality of life. Treatment of facial erythema with intradermal botulinum toxin injection has previously been reported. The primary objective of the study was the safety and efficacy of thermal decomposition of the stratum corneum using a novel non-laser thermomechanical system (Tixel, Novoxel, Israel) to increase skin permeability for Botulinum toxin in the treatment of facial flushing of rosacea. Read More

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http://doi.wiley.com/10.1002/lsm.23023
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http://dx.doi.org/10.1002/lsm.23023DOI Listing
October 2018
15 Reads

Perfluorodecalin-infused patch in picosecond and Q-switched laser-assisted tattoo removal: Safety in Fitzpatrick IV-VI skin types.

Lasers Surg Med 2019 Jan 12;51(1):23-26. Epub 2018 Oct 12.

Department of Dermatology, University of Texas Health Sciences Center, Houston, Texas.

Background: The topical transparent perfluorodecalin-infused (PFD) silicone patch has been demonstrated to reduce epidermal whitening produced in association with laser-assisted tattoo removal. This optical clearing agent has enabled multiple laser passes to be made in one treatment session. Previous studies using the PFD patch have showed enhanced clearance with picosecond and Q-Switched lasers on blue/black tattoos in Fitzpatrick skin types I-III. Read More

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http://doi.wiley.com/10.1002/lsm.23022
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http://dx.doi.org/10.1002/lsm.23022DOI Listing
January 2019
7 Reads

Laser threshold and cell damage mechanism for intravascular photoacoustic imaging.

Lasers Surg Med 2018 Oct 10. Epub 2018 Oct 10.

Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia.

Objectives: Intravascular photoacoustic (IVPA) imaging is being developed to image atherosclerotic plaques, a leading cause of morbidity and mortality in the United States. However, the safety of this imaging modality, which requires repeated irradiation with short laser pulses, has not yet been investigated. This study has two objectives. Read More

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http://doi.wiley.com/10.1002/lsm.23026
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http://dx.doi.org/10.1002/lsm.23026DOI Listing
October 2018
10 Reads