3,569 results match your criteria Lasers in Surgery and Medicine [Journal]


Science and peace.

Authors:
Kristen M Kelly

Lasers Surg Med 2018 Dec 18. Epub 2018 Dec 18.

Beckman Laser Institute, University of California, Irvine, California 92697.

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http://dx.doi.org/10.1002/lsm.23043DOI Listing
December 2018

Retraction statement: Dental hard tissue ablation using mid-infrared tunable nanosecond pulsed Cr:CdSe laser.

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Lasers Surg Med 2018 Dec 19;50(10):1052. Epub 2018 Nov 19.

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http://dx.doi.org/10.1002/lsm.23040DOI Listing
December 2018

Society Update.

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Lasers Surg Med 2018 Dec;50(10):1050-1051

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http://dx.doi.org/10.1002/lsm.22733DOI Listing
December 2018

Induction of fat apoptosis by a non-thermal device: Mechanism of action of non-invasive high-intensity electromagnetic technology in a porcine model.

Lasers Surg Med 2018 Dec 14. Epub 2018 Dec 14.

Veterinary Research Institute, Brno, Czech Republic.

Objectives: While controlled thermal changes in subcutaneous tissue have been used to trigger apoptosis of fat cells and have been proven clinically efficacious, another mechanism of electromagnetic stress suggests that fat apoptosis could be achieved by a non-thermal manner as well. This animal model study investigates the use of a non-invasive high-intensity magnetic field device to induce apoptosis in fat cells.

Methods: Yorkshire pigs (N = 2) received one treatment (30 minutes) in the abdominal area using a High-Intensity Focused Electromagnetic (HIFEM) device. Read More

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http://dx.doi.org/10.1002/lsm.23039DOI Listing
December 2018
2 Reads

Outcomes of long-pulsed 1064 nm Nd:YAG laser treatment of basal cell carcinoma: A retrospective review.

Lasers Surg Med 2018 Dec 3. Epub 2018 Dec 3.

Department of Dermatology, University of California, San Diego School of Medicine, 9500 Gillman Drive, La Jolla, California, 92093.

Background And Objective: Recent prospective trials have supported treatment of nonfacial BCC with long-pulsed 1064 nm Nd:YAG laser based on short-term histologic clearance rates. Studies have yet to identify the long-term clinical clearance rates of this specific laser therapy for BCC.

Study Design/material And Methods: This is a retrospective review of BCC treated with long-pulsed 1064 nm Nd:YAG laser, which have been clinically monitored for at least 6 months, to assess for recurrence and cosmetic outcomes of the treated area. Read More

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http://dx.doi.org/10.1002/lsm.23041DOI Listing
December 2018

Treatment of poikiloderma of Civatte using a redesigned pulsed dye laser with a 15 mm diameter treatment spot.

Lasers Surg Med 2018 Nov 27. Epub 2018 Nov 27.

Syneron-Candela Corporation, Wayland, Massachusetts.

Objectives: The pulsed-dye laser has long been a gold standard in the treatment of poikiloderma of Civatte. Recent advances in pulsed dye laser technology enable output energies 50% higher, enabling beam diameters of up to 15 mm with clinically relevant fluences. In this study, we investigate this new laser for treatment of this condition. Read More

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http://doi.wiley.com/10.1002/lsm.23036
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http://dx.doi.org/10.1002/lsm.23036DOI Listing
November 2018
4 Reads

Clinical benefit of using a multifractional Er:YAG laser combined with a spatially modulated ablative (SMA) module for the treatment of striae distensae: A prospective pilot study in 20 patients.

Lasers Surg Med 2018 Nov 27. Epub 2018 Nov 27.

Department of Plastic, Reconstructive and Maxillo facial Surgery, Hopital Henri Mondor, Creteil, 94010, France.

Background And Objective: Striae distensae (SD) are cutaneous lesions that often occur on the breasts, abdomen, hips, and thighs. The aim of this study is to evaluate the effectiveness of a new technique using a non-invasive Er:YAG laser combined with Spatially Modulated Ablation (SMA) module for the treatment of SD.

Study Design/materials And Methods: This prospective pilot clinical study included 20 patients with skin phototypes I to IV who are affected by SD. Read More

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http://doi.wiley.com/10.1002/lsm.23042
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http://dx.doi.org/10.1002/lsm.23042DOI Listing
November 2018
5 Reads
2.619 Impact Factor

Treatment of benign pigmented lesions using a novel Dermal Cooling System.

Lasers Surg Med 2018 Nov 27. Epub 2018 Nov 27.

Department of Dermatology, University of California San Diego, La Jolla 92122, California.

Benign pigmented lesions are among the most common dermatologic diagnoses that patients seek treatments for. Treatment modalities range from cryotherapy to light and laser-based technologies. These treatments have been shown to be effective, yet may lead to dyschromia or significant downtime. Read More

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http://dx.doi.org/10.1002/lsm.23037DOI Listing
November 2018
1 Read

Soft tissue cutting efficiency by 980 nm laser with carbon-, erbium-, and titanium-doped optothermal fiber converters.

Lasers Surg Med 2018 Nov 15. Epub 2018 Nov 15.

ITMO University, Saint-Petersburg, Russian Federation.

Objectives: The use of near-IR diode lasers for contact soft tissue surgery is attended by a risk of severe thermal damage of surrounding tissues due to the low cutting efficiency of these lasers. To increase the cutting efficiency of a near-IR lasers in contact surgery special tips (converters) which transform laser light to heat are used. The present in vivo study evaluated temperature dynamics and soft tissue cutting efficiency of 980 nm diode laser equipped with standard carbon- and novel erbium- and titanium-doped converters. Read More

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http://doi.wiley.com/10.1002/lsm.23006
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http://dx.doi.org/10.1002/lsm.23006DOI Listing
November 2018
2 Reads

Assessment of combined fractional CO and tranexamic acid in melasma treatment.

Lasers Surg Med 2018 Nov 15. Epub 2018 Nov 15.

Dermatology Department, Cairo University Kasr Alainy Faculty of Medicine, Cairo, Egypt.

Background: Melasma continues to be a disease that is difficult to treat with no fully satisfactory results. The role of a fractional CO laser in its treatment is controversial. The addition of tranexamic acid (TXA) might be helpful. Read More

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http://doi.wiley.com/10.1002/lsm.23032
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http://dx.doi.org/10.1002/lsm.23032DOI Listing
November 2018
8 Reads

Energy-based treatment for gynecologic conditions including genitourinary syndrome of menopause: Consensus, controversies, recommendations, and FDA clearance.

Lasers Surg Med 2018 Nov 8. Epub 2018 Nov 8.

Department of Gynecology, Uroclinica, Mendoza, Argentina Department of Laser Surgery, Palmares Hospital, Mendoza, Argentina.

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http://dx.doi.org/10.1002/lsm.23031DOI Listing
November 2018

Comparison of treatment options for small to medium congenital melanocytic nevi: A retrospective review of 119 cases.

Lasers Surg Med 2018 Oct 30. Epub 2018 Oct 30.

Department of Dermatology, Gangnam Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.

Objectives: For small to medium sized congenital melanocytic nevi (CMN), the treatment of choice is staged surgical excision. Ablative lasers or pigment-specific lasers have also been recommended for lesions difficult for surgical removal or to avoid surgery. In this study, we retrospectively analyzed the results of several treatment options for CMN to find out the optimal treatment method. Read More

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http://doi.wiley.com/10.1002/lsm.23030
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http://dx.doi.org/10.1002/lsm.23030DOI Listing
October 2018
4 Reads

Setting appropriate pain expectations: Lessons learned from a clinical trial.

Lasers Surg Med 2018 Oct 30. Epub 2018 Oct 30.

SkinCare Physicians, 1244 Boylston Street, Chestnut Hill, 02467, Massachusetts.

Objective: This retrospective study compares subject-reported pain levels and expectations set forth by industry and treating physicians during a clinical trial of an energy based device. The physiologic and emotional aspects of pain expectations are discussed and recommendations are made for strategic patient counseling.

Materials And Methods: Average and mode pain scores were collected from the records of a previously conducted clinical trial investigating a radiofrequency microneedling device at three different settings. Read More

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http://dx.doi.org/10.1002/lsm.23029DOI Listing
October 2018

Evaluation of the safety and efficacy of the dual wavelength picosecond laser for the treatment of benign pigmented lesions in Asians.

Lasers Surg Med 2018 Oct 25. Epub 2018 Oct 25.

Division of Dermatology, Department of Medicine, The University of Hong Kong, Hong Kong SAR, China.

Background And Objectives: Cutaneous pigmentary disorders are both more common and more difficult to treat in patients with skin color given the higher melanin content in the epidermis. Although Q-switched lasers are widely considered to be the standard treatment for both epidermal and dermal pigmentary conditions, a very high risk of post-inflammatory hyperpigmentation (PIH) of up to 25% is seen in patients with skin of color. Recently, the novel picosecond laser with pulse durations operating at sub-nanosecond domains has been shown to be effective in tattoo removal and in the treatment of acne scars. Read More

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http://doi.wiley.com/10.1002/lsm.23028
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http://dx.doi.org/10.1002/lsm.23028DOI Listing
October 2018
15 Reads

Using reflectance confocal microscopy to observe in vivo melanolysis after treatment with the picosecond alexandrite laser and Q-switched Nd:YAG laser in melasma.

Lasers Surg Med 2018 Oct 23. Epub 2018 Oct 23.

Department of Dermatology, School of Medicine, Kyung Hee University, Seoul, Korea.

Objectives: Melasma is an acquired type of hyperpigmentation that is characterized by the appearance of scattered light- to dark-brown macules and patches on the face. Recently, several lasers have been proposed as treatment options for melasma. In particular, the picosecond alexandrite laser is an ideal laser for selective photothermal melanolysis. Read More

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http://dx.doi.org/10.1002/lsm.23025DOI Listing
October 2018
1 Read

Society Update.

Authors:

Lasers Surg Med 2018 Sep;50(9):973-974

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http://dx.doi.org/10.1002/lsm.22731DOI Listing
September 2018

Lidocaine-induced potentiation of thermal damage in skin and carcinoma cells.

Lasers Surg Med 2018 Oct 15. Epub 2018 Oct 15.

Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts.

Objective: Lidocaine acts as a local anesthetic by blocking transmembrane sodium channel permeability, but also induces the synthesis of heat shock proteins and sensitizes cells to hyperthermia. A previous study reported two cases of deep focal skin ulceration at points corresponding to depot local lidocaine injection sites after treatment with non-ablative fractional resurfacing and it was hypothesized that lidocaine had focally sensitized keratinocytes to the thermal damage of laser treatment. The objective of this study was to investigate whether lidocaine potentiates hyperthermia damage to both normal and cancerous skin cells using an in vitro model. Read More

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http://dx.doi.org/10.1002/lsm.23027DOI Listing
October 2018
2 Reads

Long pulsed dye laser with a back-to-back double-pulse technique and compression for the treatment of epidermal pigmented lesions.

Lasers Surg Med 2018 Oct 15. Epub 2018 Oct 15.

Department of Dermatology, Northwestern University Feinberg School of Medicine, 676 N. St. Clair Street, Suite 1600, Chicago 60611, Illinois.

Background: In the recent past, long pulsed dye lasers (LPDL) have been investigated for the treatment of epidermal pigmented lesions (EPLs). Using a pigmented lesion compression headpiece, blood is pushed laterally out of the laser field focusing laser energy on melanin. Recent studies have demonstrated excellent responses using a single-pulse at the following settings: 9-12 J/cm , 1. Read More

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http://doi.wiley.com/10.1002/lsm.23009
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http://dx.doi.org/10.1002/lsm.23009DOI Listing
October 2018
2 Reads

The toxic edge-A novel treatment for refractory erythema and flushing of rosacea.

Lasers Surg Med 2018 Oct 12. Epub 2018 Oct 12.

Department of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Purpose: Rosacea is a common, chronic facial skin disease that affects the quality of life. Treatment of facial erythema with intradermal botulinum toxin injection has previously been reported. The primary objective of the study was the safety and efficacy of thermal decomposition of the stratum corneum using a novel non-laser thermomechanical system (Tixel, Novoxel, Israel) to increase skin permeability for Botulinum toxin in the treatment of facial flushing of rosacea. Read More

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http://doi.wiley.com/10.1002/lsm.23023
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http://dx.doi.org/10.1002/lsm.23023DOI Listing
October 2018
10 Reads

Perfluorodecalin-infused patch in picosecond and Q-switched laser-assisted tattoo removal: Safety in Fitzpatrick IV-VI skin types.

Lasers Surg Med 2018 Oct 12. Epub 2018 Oct 12.

Department of Dermatology, University of Texas Health Sciences Center, Houston, Texas.

Background: The topical transparent perfluorodecalin-infused (PFD) silicone patch has been demonstrated to reduce epidermal whitening produced in association with laser-assisted tattoo removal. This optical clearing agent has enabled multiple laser passes to be made in one treatment session. Previous studies using the PFD patch have showed enhanced clearance with picosecond and Q-Switched lasers on blue/black tattoos in Fitzpatrick skin types I-III. Read More

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http://doi.wiley.com/10.1002/lsm.23022
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http://dx.doi.org/10.1002/lsm.23022DOI Listing
October 2018
6 Reads

Laser threshold and cell damage mechanism for intravascular photoacoustic imaging.

Lasers Surg Med 2018 Oct 10. Epub 2018 Oct 10.

Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia.

Objectives: Intravascular photoacoustic (IVPA) imaging is being developed to image atherosclerotic plaques, a leading cause of morbidity and mortality in the United States. However, the safety of this imaging modality, which requires repeated irradiation with short laser pulses, has not yet been investigated. This study has two objectives. Read More

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http://doi.wiley.com/10.1002/lsm.23026
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http://dx.doi.org/10.1002/lsm.23026DOI Listing
October 2018
6 Reads

High intensity focused electromagnetic therapy evaluated by magnetic resonance imaging: Safety and efficacy study of a dual tissue effect based non-invasive abdominal body shaping.

Lasers Surg Med 2018 Oct 10. Epub 2018 Oct 10.

Paula Fines Center, Sofia BG, Europe.

Objectives: This study introduces an initial evaluation of a novel High-Intensity Focused Electromagnetic (HIFEM) technology. The primary goal is to quantify any effects the treatments may have on abdominal tissues, as well as to establish hypotheses for future research of this technology.

Methods: Twenty-two patients received four abdominal treatments using the EMSCULPT device (BTL Industries Inc. Read More

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http://doi.wiley.com/10.1002/lsm.23024
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http://dx.doi.org/10.1002/lsm.23024DOI Listing
October 2018
12 Reads

Full ablative versus fractional ablative laser therapy for Dowling-Degos disease.

Lasers Surg Med 2018 Oct 3. Epub 2018 Oct 3.

Department of Dermatology, Venereology and Allergology, Universitätsklinikum Leipzig AöR, 04103, Leipzig, Germany.

Dowling-Degos disease (DDD) is a rare autosomal-dominant genodermatosis with limited treatment possibilities. Although the efficacy of ablative laser therapy has been reported, we sought to examine the efficacy of fractional versus full ablative laser therapy in a female patient with DDD in a split-side report. We treated the lesions on the right side of the patient's upper abdomen with an ablative fractional CO laser and the lesions on the left side of the upper abdomen with a full ablative Er:YAG laser (erbium-doped yttrium aluminium garnet laser) three times at monthly intervals. Read More

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http://doi.wiley.com/10.1002/lsm.23021
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http://dx.doi.org/10.1002/lsm.23021DOI Listing
October 2018
1 Read

2-deoxy-D-glucose augments photodynamic therapy induced mitochondrial caspase-independent apoptosis and energy-mediated autophagy.

Lasers Surg Med 2018 Sep 17. Epub 2018 Sep 17.

Key Laboratory of Medicinal Resources and Natural Pharmaceutical Chemistry, Ministry of Education, National Engineering Laboratory for Resource Developing of Endangered Chinese Crude Drugs in Northwest of China, College of Life Sciences, Shaanxi Normal University, Xi'an, Shaanxi, China.

Objectives: Compared to normal cells, malignant cells have a high degree of aerobic glycolysis, also known as the Warburg effect. Therefore, supplementing photodynamic therapy (PDT), an established cancer therapy, with metabolic inhibitors can augment the mitochondrial damage by depleting ATP. To assess the combined impact of the glycolysis inhibitor 2-deoxy-D-glucose (2-DG) and PDT on apoptosis and autophagy in human breast cancer cells, and examine the molecular basis. Read More

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http://dx.doi.org/10.1002/lsm.23020DOI Listing
September 2018

Feature characterization of scarring and non-scarring types of alopecia by multiphoton microscopy.

Lasers Surg Med 2018 Sep 24. Epub 2018 Sep 24.

Department of Dermatology, University of California, Irvine, California.

Objectives: Non-invasive visualization of hair follicles is important for proper diagnosis and management of alopecia; however, histological assessment remains the gold standard. Laser imaging technologies have made possible noninvasive in vivo evaluation of skin and hair follicle. The aim of this study was to evaluate the ability of multiphoton microscopy (MPM) to non-invasively identify morphological features that can distinguish scarring from non-scarring alopecia. Read More

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http://dx.doi.org/10.1002/lsm.23017DOI Listing
September 2018
2 Reads

News & Announcements: American Society for Laser Medicine and Surgery, Inc.

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Lasers Surg Med 2018 Oct;50(8):883-885

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http://dx.doi.org/10.1002/lsm.22729DOI Listing
October 2018

Effects of transcranial photobiomodulation with near-infrared light on sexual dysfunction.

Lasers Surg Med 2018 Sep 17. Epub 2018 Sep 17.

Department of Psychiatry, Nathan Kline Institute for Psychiatric Research, Orangeburg, New York.

Objectives: Transcranial photobiomodulation (t-PBM) consists of the delivery of near-infrared (NIR) or red light to the scalp designed to penetrate to subjacent cortical areas of the brain. NIR t-PBM has recently emerged as a potential therapy for brain disorders. This study assessed the efficacy of repeated sessions of NIR t-PBM on sexual dysfunction. Read More

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http://dx.doi.org/10.1002/lsm.23011DOI Listing
September 2018
2 Reads

Development and evaluation of a low-cost, portable, LED-based device for PDT treatment of early-stage oral cancer in resource-limited settings.

Lasers Surg Med 2018 Aug 31. Epub 2018 Aug 31.

Department of Physics, University of Massachusetts, Boston, Massachusetts, 02125.

Background: Photodynamic therapy (PDT) using δ-aminolevulinic acid (ALA) photosensitization has shown promise in clinical studies for the treatment of early-stage oral malignancies with fewer potential side effects than traditional therapies. Light delivery to oral lesions can also carried out with limited medical infrastructure suggesting the potential for implementation of PDT in global health settings.

Objectives: We sought to develop a cost-effective, battery-powered, fiber-coupled PDT system suitable for intraoral light delivery enabled by smartphone interface and embedded electronics for ease of operation. Read More

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http://dx.doi.org/10.1002/lsm.23019DOI Listing
August 2018
12 Reads

Does blue light restore human epidermal barrier function via activation of Opsin during cutaneous wound healing?

Lasers Surg Med 2018 Aug 31. Epub 2018 Aug 31.

Centre for Skin Sciences, Faculty of Life Sciences, University of Bradford, Bradford, United Kingdom.

Background And Objective: Visible light has beneficial effects on cutaneous wound healing, but the role of potential photoreceptors in human skin is unknown. In addition, inconsistency in the parameters of blue and red light-based therapies for skin conditions makes interpretation difficult. Red light can activate cytochrome c oxidase and has been proposed as a wound healing therapy. Read More

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http://dx.doi.org/10.1002/lsm.23015DOI Listing
August 2018
4 Reads

Efficacy and safety of picosecond 755-nm alexandrite laser with diffractive lens array for non-ablative rejuvenation in Chinese skin.

Lasers Surg Med 2018 Aug 28. Epub 2018 Aug 28.

Division of Dermatology, Department of Medicine, The University of Hong Kong, Hong Kong SAR, China.

Background And Objectives: The picosecond alexandrite laser with diffractive lens array (DLA) offers the dual advantages of a picosecond pulse duration and the fractionated delivery of laser energy. This study explores the efficacy and safety of the DLA for treatment of multiple aesthetic concerns associated with photoaging of the face including skin texture irregularities, dyspigmentation, enlarged pore size, rhytides, and skin laxity.

Methods: This prospective, evaluator-blinded trial enrolled Fitzpatrick skin type III-IV patients with mild to moderate signs of facial photoaging. Read More

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http://doi.wiley.com/10.1002/lsm.23014
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http://dx.doi.org/10.1002/lsm.23014DOI Listing
August 2018
7 Reads

Topical delivery of vismodegib using ablative fractional laser and micro-emulsion formulation in vitro.

Lasers Surg Med 2018 Aug 28. Epub 2018 Aug 28.

Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.

Background And Objective: Hedgehog inhibitors such as vismodegib are targeted drugs widely used for the treatment of basal cell carcinomas; however, their use is significantly limited by frequent systemic side effects due to oral administration route. We aim to use ablative fractional laser (AFL) to enable the topical delivery of vismodegib to relevant dermal depths.

Materials And Methods: Pig skin was treated in vitro with a fractional 10,600 nm CO laser at 0 or 80 mJ/microbeam and exposed to vismodegib (6. Read More

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http://dx.doi.org/10.1002/lsm.23013DOI Listing

In-depth analysis of antibacterial mechanisms of laser generated shockwave treatment.

Lasers Surg Med 2018 Aug 28. Epub 2018 Aug 28.

Department of Bioengineering, University of California, Los Angeles (UCLA) Henry Samueli School of Engineering and Applied Science, Los Angeles, California.

Background and Objectives Laser generated shockwave (LGS) is a novel modality for minimally invasive disruption of bacterial biofilms. The objectives of this study are to determine the mechanisms behind LGS treatment and non-biofilm effects on bacterial disruption, including (1) comparing bacterial load with and without LGS in its planktonic form and (2) estimating bacterial cell permeability following LGS. Study Design/Materials and Methods For the first study, planktonic S. Read More

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http://doi.wiley.com/10.1002/lsm.23018
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http://dx.doi.org/10.1002/lsm.23018DOI Listing
August 2018
6 Reads

Treatment of dissecting cellulitis of the scalp with 10% ALA-PDT.

Lasers Surg Med 2018 Aug 23. Epub 2018 Aug 23.

Department of Dermatology, The First Hospital of China Medical University, Shenyang, China.

Background: Dissecting cellulitis of the scalp (DCS) is difficult to be treated and 5-aminolaevulinic acid photodynamic therapy (ALA-PDT) is considered to be a potential treatment for inflammatory skin diseases.

Objective: To analyze the efficacy and safety of ALA-PDT on DCS.

Materials And Methods: The treatment areas of DCS patients were incubated with freshly prepared 10% ALA for 3 hours. Read More

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http://dx.doi.org/10.1002/lsm.23016DOI Listing
August 2018
7 Reads

Mobile phone-based UV fluorescence microscopy for the identification of fungal pathogens.

Lasers Surg Med 2018 Aug 16. Epub 2018 Aug 16.

Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts.

Background And Objective: Dermatophytes are fungi that cause infections in hair, skin, and nails. Potassium Hydroxide (KOH) microscopy is the most frequently used method for identifying dermatophytes. KOH helps in the visualization of the hyphae as it clears the debris present in the specimen but needs a trained eye for final diagnosis of the infection. Read More

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http://dx.doi.org/10.1002/lsm.23012DOI Listing
August 2018
3 Reads

Efficacy of adjunctive photodynamic therapy in the treatment of generalized aggressive periodontitis: A randomized controlled clinical trial.

Lasers Surg Med 2018 Aug 10. Epub 2018 Aug 10.

Faculty of Dentistry, Department of Periodontology, Marmara University, Istanbul, Turkey.

Objectives: Generalized aggressive periodontitis (GAgP) is a distinct type of periodontal disease characterized by rapid loss of attachment and alveolar bone occurring in young individuals. Photodynamic therapy (PDT) was introduced in periodontology as an adjunctive approach to non-surgical periodontal treatment (NPT) in periodontitis patients. In this trial, the aim was to evaluate the clinical and microbiological effects of adjunctive PDT to NPT in patients with GAgP. Read More

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http://dx.doi.org/10.1002/lsm.23010DOI Listing
August 2018
11 Reads
2.620 Impact Factor

Sequential facial skin rejuvenation with intense pulsed light and non-ablative fractionated laser resurfacing in fitzpatrick skin type II-IV patients: A prospective multicenter analysis.

Lasers Surg Med 2018 Aug 8. Epub 2018 Aug 8.

Dermatological Practice-Laser Center, Konz, Germany.

Background: While skin aging is triggered by multiple factors and typically presents with multiple manifestations, conventional treatment regimens deploy a single treatment modality. Typical approaches exploit ablative techniques, which involve considerable patient discomfort and downtime and can induce adverse events. Non-ablative fractionated laser (NAFL) resurfacing promotes neocollagenesis, with significantly fewer complications and discomfort. Read More

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http://doi.wiley.com/10.1002/lsm.23007
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http://dx.doi.org/10.1002/lsm.23007DOI Listing
August 2018
10 Reads

Acne vulgaris severity graded by in vivo reflectance confocal microscopy and optical coherence tomography.

Lasers Surg Med 2018 Aug 2. Epub 2018 Aug 2.

Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.

Introduction: Acne is an inflammatory disease of the pilosebaceous unit, which can be investigated in vivo using reflectance confocal microscopy (RCM) and optical coherence tomography (OCT).

Objectives: By means of RCM and OCT to identify morphological characteristics of acne that may be associated with clinical acne severity.

Methods: Patients with mild to moderate facial acne (n = 14, Investigators Global Assessment scale, IGA 1-3), and healthy participants (n = 7, IGA 0) were included in this explorative study. Read More

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http://dx.doi.org/10.1002/lsm.23008DOI Listing
August 2018
1 Read

1.7 micron optical coherence tomography for vaginal tissue characterization in vivo.

Lasers Surg Med 2018 Jul 30. Epub 2018 Jul 30.

Beckman Laser Institute, University of California, Irvine, California, 92617.

Objectives: Optical coherence tomography (OCT) can noninvasively visualize in vivo tissue microstructure with high spatial resolution that approaches the histologic level. Currently, OCT studies in gynecology are few and limited to a conventional 1.3 μm center wavelength swept light source which provides high spatial resolution but limited penetration depth. Read More

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http://dx.doi.org/10.1002/lsm.23003DOI Listing
July 2018
2.620 Impact Factor

Upper airway reconstruction using long-range optical coherence tomography: Effects of airway curvature on airflow resistance.

Lasers Surg Med 2018 Jul 26. Epub 2018 Jul 26.

Beckman Laser Institute, University of California, Irvine, California.

Objectives: Adenotonsillectomy (AT) is commonly used to treat upper airway obstruction in children, but selection of patients who will benefit most from AT is challenging. The need for diagnostic evaluation tools without sedation, radiation, or high costs has motivated the development of long-range optical coherence tomography (LR-OCT), providing real-time cross-sectional airway imaging during endoscopy. Since the endoscope channel location is not tracked in conventional LR-OCT, airway curvature must be estimated and may affect predicted airway resistance. Read More

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http://dx.doi.org/10.1002/lsm.23005DOI Listing

Plasmonic photothermal therapy: Approaches to advanced strategy.

Lasers Surg Med 2018 Dec 19;50(10):1025-1033. Epub 2018 Jul 19.

Saratov State Medical University (National Research University), 83 Astrakhanskaya str., Saratov 410012, Russia.

Background: The analysis of recent studies on plasmonic photothermal therapy (PPT) after intravenous administration of gold nanorods (GNRs) has demonstrated that the effectiveness of nanoparticle-assisted laser hyperthermia depends on a correct dosage strategy of nanoparticle administration. Accumulation of GNRs in tumor tissue dramatically increases the local heating of the tumor without damage to healthy tissues. However, the optimal doses of GNR intravenous injections (IVIs) for effective accumulation in tumors, and optimal protocols of PPT are not designed yet. Read More

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http://dx.doi.org/10.1002/lsm.23001DOI Listing
December 2018
3 Reads

A clinical study of choledochoscopic holmium laser lithotripsy for multiple intrahepatic calculi within ERAS programs.

Lasers Surg Med 2018 Jul 19. Epub 2018 Jul 19.

Department of Hepatobiliary Surgery, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, 150 Ximen Street, Linhai 317000, China.

Objectives: Multiple intrahepatic calculi, especially calculi in both sides of the liver, cannot be completely resolved by traditional surgery. In addition, morbidity after liver resection remains high. ERAS programs have been suggested that could relieve surgical stress and accelerate postoperative recovery. Read More

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http://dx.doi.org/10.1002/lsm.23004DOI Listing
July 2018
2 Reads

Selective ablation of dental caries using coaxial Co (9.3-μm) and near-IR (1880-nm) lasers.

Lasers Surg Med 2018 Jul 19. Epub 2018 Jul 19.

Department of Preventive and Restorative Dental Sciences, University of California, San Francisco, San Francisco 94143-0758, California.

Objective: The purpose of this study was to determine the feasibility of image-guided laser ablation of demineralization from tooth occlusal surfaces using coaxial near-infrared (NIR) and CO lasers.

Materials And Methods: A CO laser operating at a wavelength of 9.3-μm was combined with a thulium-doped fiber laser operating at 1880-nm for the selective removal of simulated occlusal caries lesions from 10 tooth samples. Read More

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http://dx.doi.org/10.1002/lsm.23002DOI Listing
July 2018
5 Reads
2.620 Impact Factor

Automating neurosurgical tumor resection surgery: Volumetric laser ablation of cadaveric porcine brain with integrated surface mapping.

Lasers Surg Med 2018 Dec 9;50(10):1017-1024. Epub 2018 Jul 9.

Department of Neurosurgery, Duke University School of Medicine, Durham, North Carolina.

Objective: Current surgical instruments for soft tissue resection including neurosurgical procedures rely on the accuracy and precision of the human operator and are fundamentally constrained by the human hand. Automated surgical action with the integration of intraoperative data sources can enable highly accurate and fast tissue manipulation using laser ablation. This study presents the first experiments with a prototype designed for automated tumor resection via laser ablation. Read More

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http://dx.doi.org/10.1002/lsm.23000DOI Listing
December 2018
1 Read

Sentinel lymphadenectomy in cervical cancer using near infrared fluorescence from indocyanine green combined with technetium-99m-nanocolloid.

Lasers Surg Med 2018 Dec 3;50(10):994-1001. Epub 2018 Jul 3.

Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany.

Objective: Sentinel diagnostic in cervical cancer is performed using Technetium-99m-nanocolloid as a radioactive marker with or without patent blue. In the last years, indocyanine green has been evaluated for sentinel diagnostic in different tumor entities. Indocyanine green is a fluorescent molecule which emits a light signal in the near infrared band after excitation. Read More

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http://dx.doi.org/10.1002/lsm.22999DOI Listing
December 2018
13 Reads

Choroidal remodeling after photodynamic therapy for polypoidal choroidal vasculopathy.

Lasers Surg Med 2018 Dec 28;50(10):978-979. Epub 2018 Jun 28.

Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.1002/lsm.22998DOI Listing
December 2018
2 Reads

Assessing fluorescence detection and effective photothermal therapy of near-infrared polymer nanoparticles using alginate tissue phantoms.

Lasers Surg Med 2018 Dec 28;50(10):1040-1049. Epub 2018 Jun 28.

Department of Plastic and Reconstructive Surgery, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157.

Objective: Photothermal therapy (PTT) uses light absorbing materials to generate heat for treatment of diseases, like cancer. The advantages of using PTT components that absorb in the near-infrared (NIR) include reduced tissue auto-fluorescence and higher penetration depths. However, NIR laser light can still be scattered and absorbed by biological tissues, thus decreasing the amount of the energy reaching the PTT agents. Read More

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http://dx.doi.org/10.1002/lsm.22955DOI Listing
December 2018
6 Reads

Accelerated tattoo removal with acoustic shock wave therapy in conjunction with a picosecond laser.

Lasers Surg Med 2018 Sep 25;50(9):890-892. Epub 2018 Jun 25.

Department of Dermatology, University of Texas Health Sciences Center, Houston, Texas.

Background: Conventional tattoo removal consists of single-pass treatments, spaced 7-8 weeks apart, for a total of 7-10 sessions. A major limiting factor of this procedure is the development of cavitation bubbles and vacuoles within the epidermis and dermis that result from the rapid heating of tattoo particles by the laser. While multiple-pass methods using the R20 protocol or the PFD patch enhance tattoo removal through epidermal clearance, they have no effect on deep-intradermal pigment associated vacuoles that arise from treatment with lasers such as the Q-switched laser. Read More

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http://doi.wiley.com/10.1002/lsm.22945
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http://dx.doi.org/10.1002/lsm.22945DOI Listing
September 2018
25 Reads

News & Announcements: American Society for Laser Medicine and Surgery, Inc.

Authors:

Lasers Surg Med 2018 Jul;50(5):599-603

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http://dx.doi.org/10.1002/lsm.22954DOI Listing
July 2018
1 Read

Topical brimonidine reduces IPL-induced erythema without affecting efficacy: A randomized controlled trial in patients with facial telangiectasias.

Lasers Surg Med 2018 Dec 17;50(10):1002-1009. Epub 2018 Jun 17.

Department of Dermatology, Bispebjerg University Hospital, Copenhagen, Denmark.

Background: Laser and intense pulsed light (IPL) are standard symptomatic treatments for superficial telangiectasias, but postoperative erythema, oedema, and pain may prolong downtime.

Objectives: To investigate whether topical brimonidine reduces IPL-induced inflammation in patients with moderate to severe facial telangiectasias.

Methods: A randomized, two-centre, single-blinded, split-face trial on adjuvant brimonidine and air-cooling versus air-cooling alone (control) in 19 patients treated in Denmark (n = 10 patients) and Belgium (n = 9). Read More

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http://dx.doi.org/10.1002/lsm.22953DOI Listing
December 2018
16 Reads

Fractional carbon dioxide laser resurfacing of skin grafts: long-term results of a prospective, randomized, split-scar, evaluator-blinded study.

Lasers Surg Med 2018 Dec 17;50(10):1010-1016. Epub 2018 Jun 17.

Department of Dermatology, University Medical Centre Regensburg, 93042, Regensburg, Germany.

Background: Fractional ablative resurfacing is frequently used for treating atrophic and acne scars as well as for the early improvement of scars after surgery. No evidence-based clinical data on improving the appearance of skin grafts by fractional CO -laser resurfacing have been available so far.

Objectives: The primary outcome parameter was the adaptation of the skin graft to the surrounding skin 2, 6, and 12 months after the second laser treatment. Read More

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http://dx.doi.org/10.1002/lsm.22950DOI Listing
December 2018