Search Our Scientific Publications & Authors

J Cosmet Dermatol 2020 Jun 5. Epub 2020 Jun 5.

Derma- Care skin and cosmetology Centre, Mangalore, India.

Fractional CO laser is an accepted and preferred form of treatment for resurfacing of all scars- accident scars, burn scars and acne scars. In 2004, Manstein et al. introduced the concept of fractional photothermolysis. Read More

Lasers Surg Med 2020 Apr 29. Epub 2020 Apr 29.

DeLozier Cosmetic Surgery Center, 209 23rd Ave N, Nashville, Tennessee, 37203.

Background And Objectives: A novel helium plasma device was evaluated for efficacy and safety for dermal resurfacing (ClinicalTrials.gov Identifier: NCT03286283). The helium plasma device delivers energy in a controlled, bimodal fashion that when compared with the nitrogen plasma predicate device in a porcine animal model demonstrated a more limited depth of thermal effect but a greater skin tissue contraction. Read More

Plast Reconstr Surg Glob Open 2020 Feb 26;8(2):e2640. Epub 2020 Feb 26.

Swanson Center, Leawood, KS.

Background: Despite their name, "short scar" procedures leave scars in the temples and the postauricular scar often requires extension. Redraping the orbicularis muscle for periorbital rejuvenation increases the risk of facial nerve injury. This retrospective cohort study was undertaken to clinically evaluate a surgical approach that eliminates the temporal incision. Read More

Lasers Surg Med 2020 Jan 14. Epub 2020 Jan 14.

Institute of Biomedical Optics, University of Luebeck, Luebeck, 23562, Germany.

Background And Objectives: A recent generation of 5,500 nm wavelength carbon monoxide (CO) lasers could serve as a novel tool for applications in medicine and surgery. At this wavelength, the optical penetration depth is about three times higher than that of the 10,600 nm wavelength carbon dioxide (CO ) laser. As the amount of ablation and coagulation is strongly influenced by the wavelength, we anticipated that CO lasers would provide extended coagulation zones, which could be beneficial for several medical applications, such as tissue tightening effects after laser skin resurfacing. Read More

Facial Plast Surg Clin North Am 2020 Feb;28(1):17-28

Laserplast SrL StP, Piazza Eleonora Duse 2 Milano, Republic of Italy; R&D Department, Swansea Bay University Health Board and the Welsh Centre for Burns and Plastic Surgery, Moriston Hospital, Swansea SA6 6NL, United Kingdom.

Fractional CO procedures are an established, safe and effective armamentarium for managing skin rejuvenation and scarring. Very short-pulse-duration devices offer a very high ablated volume/ablated surface ratio, inducing a controlled thermal damage. With this kind of device, each procedure can be customized on the features of the skin of each patient. Read More

Dermatol Surg 2019 Oct 11. Epub 2019 Oct 11.

Department of Dermatology Naval Medical Center Camp Lejeune, Camp Lejeune, North Carolina SkinCare Physicians, Chestnut Hill, Massachusetts SkinCare Physicians, Chestnut Hill, Massachusetts SkinCare Physicians, Chestnut Hill, Massachusetts Department of Dermatology, Yale University, New Haven, Connecticut.

Plast Reconstr Surg Glob Open 2019 Jun 14;7(6):e2075. Epub 2019 Jun 14.

Dallas Plastic Surgery Institute, Dallas, Texas, USA.

Face-lift techniques have evolved beyond the concept of lifting and now include incorporating superficial and deep filling of facial fat compartments to address volume deflation and aging. In addition to traditional face-lift methods involving the excision and tightening of skin and the underlying soft tissues, the following ancillary procedures have become paramount in achieving an optimal result: blending the lid-cheek junction; chin augmentation; lobule augmentation; hand rejuvenation; perioral rejuvenation; chemical peels; and laser resurfacing. We presented a summary of these integral techniques. Read More

Skin Therapy Lett 2019 Sep;24(5):1-6

Dr. Jason Emer, West Hollywood, CA, USA

Platelet-rich plasma (PRP) is an autologous serum containing high concentrations of platelets and growth factors. PRP continues to evolve as an important treatment modality with many applications in dermatology, particularly in the areas of hair restoration, skin rejuvenation, acne scars, dermal augmentation, and striae distensae. Furthermore, combining PRP with laser therapies, microneedling, dermal fillers, and autologous fat grafting produces synergistic effects, leading to improved aesthetic results. Read More

Aesthet Surg J 2019 Oct 2. Epub 2019 Oct 2.

Division of Plastic Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA.

Background: Google Trends (GT) provides cost-free, customizable analyses of search traffic for specified terms entered into Google's search engine. GT may inform plastic surgery marketing decisions and resource allocation.

Objectives: To determine GT's utility in tracking and predicting public interest in nonsurgical cosmetic procedures and to examine trends over time of public interest in nonsurgical procedures. Read More

J Ayub Med Coll Abbottabad 2019 Jul-Sep;31(3):336-339

Jinnah Burn and Reconstructive Surgery Center, Allama Iqbal Medical College, Lahore, Pakistan.

Background: Acne effects 80-90% of teenage population all around the world. Resulting scars can lead to facial disfigurement and psychological issues in affected population. To counter this problem many treatment options have been tried including resurfacing lasers, dermabrasion, peeling, fillers, platelet rich plasma therapy etc. Read More

Aesthet Surg J 2019 Sep 5. Epub 2019 Sep 5.

Private Practice in Istanbul, Turkey.

Background: Improvements in skin erythema and elasticity have been seen with topical application of platelet-rich plasma after fractional laser treatment. Nanofat, when injected in small needles into the dermis has shown improvements in tissue thickness, discoloration and wrinkle depth.

Objective: To evaluate improvements in skin following a nonablative fractional laser (FXD) treatment combined with the application of a novel topical nanofat biocrème, called neo-U. Read More

Dermatol Ther 2019 11 7;32(6):e13084. Epub 2019 Oct 7.

Department of Dermatology, The Affiliated Hospital of North Sichuan Medical College, Nanchong, China.

Fractional ablative carbon dioxide laser resurfacing is a frontline treatment for acne scars. It creates multiple microscopic treatment zones to accelerate the collagen formation and the healing process of reepithelialization, according the principle of fractional photothermolysis. At present, the fractional CO laser with a wavelength of 10,600 nm is commonly used in the field of cosmetology and clinical therapies for various skin diseases, and it can effectively improve skin regeneration and scar formation. Read More

Biomed Res Int 2019 1;2019:6952649. Epub 2019 Jul 1.

Department of Technology Design/Laboratory of Bone Implants Research and Design, Institute of Mechanical Technology, Poznan University of Technology, Piotrowo Street 3, 60-965 Poznan, Poland.

Resurfacing hip and knee endoprostheses are generally embedded in shallow, prepared areas in the bone and secured with cement. Massive cement penetration into periarticular bone, although it provides sufficient primary fixation, leads to the progressive weakening of peri-implant bone and results in failures. The aim of this paper was to investigate in an animal model the first biomimetic fixation of components of resurfacing arthroplasty endoprostheses by means of the innovative multispiked connecting scaffold (MSC-Scaffold). Read More

Am J Clin Dermatol 2019 Oct;20(5):683-690

Advanced Dermatology, Lincolnshire and Glencoe, IL, USA.

Over the past 30 years, the treatment of acne scars has undergone changes that have been significantly influenced by the concurrent development of new devices. The advent of fractional resurfacing lasers was a watershed moment for acne scarring therapy. The author recounts a career history of considerations of acne scarring treatments as well as the literature supporting the experiences causing changes in practice. Read More

Facial Plast Surg 2019 Jun 12;35(3):248-255. Epub 2019 Jun 12.

Department of Otolaryngology - Head and Neck Surgery, Rutgers New Jersey Medical School, Summit, New Jersey.

Laser technology continues to increase in popularity and expand treatment options for patients with common but challenging skin conditions including facial telangiectasias, facial aging, striae distensae, and acne scars. Facial telangiectasias have been estimated to occur in tens of millions of people worldwide. The 585-nm laser was the first to follow the principle of selective photothermolysis for the treatment of cutaneous vascular lesions, but it caused significant postoperative purpura. Read More

Skin Res Technol 2019 Nov 22;25(6):805-809. Epub 2019 May 22.

Terahertz Science and Technology Center (C2T2) and Terahertz Science and Technology National Laboratory (LANCYTT), Universidad Autónoma de San Luis Potosí, San Luis Potosí, México.

Background: Ablative fractional laser surgery is a common technique for treating acne scars. However, an in vivo and noninvasive analysis of the histologic variations between acne skin and the resulting resurfaced skin is needed in order to evaluate the wound healing process of the scars induced by the ablative fractional laser surgery.

Materials And Methods: Nine patients with acne scars underwent a single treatment with a CO ablative fractional laser surgery. Read More

Dermatol Clin 2019 Jul;37(3):375-386

Department of Dermatology, University of California Davis Medical System, 3301 C Street, #1400, Sacramento, CA 95816, USA. Electronic address:

Scar revision is of premier importance to the dermatologic surgeon. Some of the least invasive modalities include use of silicone gel sheets, resurfacing with electrosurgical instruments, dermabrasion, chemical peels, and subcision. Laser technology also has been implemented to selectively target and ablate fibrous scar tissue via selective thermolysis. Read More

Photodiagnosis Photodyn Ther 2019 Jun 12;26:270-276. Epub 2019 Apr 12.

Department of Dermatology, Faculty of Medicine University of Debrecen, Hungary.

Introduction: Ultraviolet light induced DNA damage, combined with immunosuppression and inflammation are involved in the pathogenesis of actinic keratosis. Photodynamic therapy not only destroys dysplastic cells via tissue destruction and vascular shutdown, but also induces an acute local inflammatory response and activates both the innate and adaptive immune system. In our current work we aimed to compare immunohistochemistry features of inflammatory infiltrate of actinic keratoses after 5-aminolevulinic acid photodynamic therapy with or without Er:YAG laser resurfacing. Read More

Otolaryngol Clin North Am 2019 Jun 5;52(3):443-459. Epub 2019 Apr 5.

PLLC Plastic & Reconstructive Surgery, 969 Park Ave Suite 1G New York, NY 10028, USA; Georgetown University, Washington, DC, USA.

Minimally invasive procedures including neurotoxins, dermal fillers, deoxycholic acid, lasers, peels, and microneedling offer powerful, less permanent adjuncts to surgery that are highly effective in select patients. Injectables and skin resurfacing techniques target facial irregularities including wrinkles and fine lines, decrease in volume and contour, and unwanted fat. Determining the best approach for a given patient involves careful consideration of the patient's health conditions, unique anatomic characteristics, tissue quality, and desired results. Read More

J Cosmet Dermatol 2019 Dec 4;18(6):1751-1757. Epub 2019 Apr 4.

Department of Pediatrics, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, Thailand.

Introduction: Fractional carbon dioxide (FrCO ) laser is effective for atrophic acne scar treatment, but unavoidable downtime. Meanwhile, postoperative topical steroid decreases the downtime, yet still possibly increases other steroid side effects.

Objective: To evaluate the efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese (experimental cream) versus 0. Read More

J Craniofac Surg 2019 Sep;30(6):e535-e539

Department of Plastic and Reconstructive Surgery, School of Medicine, Kyungpook National University, Daegu.

Background: For the treatment of wide scars, laser resurfacing procedures are generally used. However, sometimes their results are not satisfactory. Many clinical studies have reported that cultured epidermal allogenic sheets promote rapid and good quality wound healing. Read More

J Drugs Dermatol 2019 Mar;18(3):274-275

The use of full-thickness skin grafts (FTSG) in facial reconstruction during dermatologic surgery is well-established. Surgical sites that commonly receive a skin graft include the scalp, nose and ear Read More

J Clin Aesthet Dermatol 2019 Jan 1;12(1):24-27. Epub 2019 Jan 1.

Drs. Comeou, Goodman, and Buckley are with the Department of Dermatology at Philadelphia College of Osteopathic Medicine in Roswell, Georgia.

Rhinophyma is a progressive, disfiguring condition that affects the nose and is caused by the hypertrophy of sebaceous glands and connective tissue. Although its exact pathogenesis remains unclear, it is generally thought to be a subtype of the chronic, inflammatory condition rosacea. To date, oral and topical treatments have been largely ineffective at treating rhinophyma. Read More

J Cosmet Dermatol 2019 Dec 1;18(6):1657-1664. Epub 2019 Mar 1.

Department of Dermatology and Cutaneous Biology Research Center, International St. Mary's Hospital, Catholic Kwandong University College of Medicine, Incheon, Korea.

Background: Low-fluenced 2940-nm erbium (Er):yttrium-aluminium-garnet (YAG) resurfacing elicits ablative photothermal tissue reactions confined to the uppermost parts of the epidermis.

Objective: To demonstrate the efficacy and safety of low-fluenced ablative Er:YAG laser treatment in combination with broadband light (BBL) pretreatment for various pigmentation disorders.

Methods: In total, 35 Korean patients with various pigmentation disorders were pretreated with BBL, and then, low-fluenced Er:YAG laser resurfacing was performed with a beam size of 4 mm and a fluence of 1. Read More

Lasers Med Sci 2019 Aug 4;34(6):1125-1135. Epub 2019 Jan 4.

Ophthalmology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.

Fractional CO laser rejuvenation of scars offers a high safety profile. Laser marks usually disappear clinically within 1 week. The authors observed occasional persistence of the laser marks on the scar surface. Read More

Lasers Med Sci 2019 Aug 3;34(6):1147-1158. Epub 2019 Jan 3.

Faculty of Physics, University of Ljubljana, Jadranska 19, 1000, Ljubljana, Slovenia.

According to the standard Arrhenius relation, tissue damage is linearly dependent on the duration of exposure to elevated temperatures and exponentially dependent on the temperature itself. However, recently published measurements of damage threshold temperatures at extremely short exposure times (commonly present during laser treatments) exhibit a shift to temperatures that are higher than what would normally be expected from a single-process Arrhenius model. A novel variable heat shock (VHS) response model was developed that takes into account the observed deviation from the single-process Arrhenius relation, by assuming that the cell viability can be described as the combined effect of two biochemical processes that dominate cell survival characteristics at very short and very long exposure times. Read More

Facial Plast Surg 2018 Dec 28;34(6):624-630. Epub 2018 Dec 28.

Department of Plastic Surgery, King Edward VII's Hospital, London, Greater London, United Kingdom.

Facelift surgery is a popular treatment but exhibits high variation among practitioners in terms of both core technique and adjunctive measures. This review identified significant evidence addressing the role of pre-infiltration, drains, fat grafting, fibrin tissue adhesives, hilotherapy, and other miscellaneous adjuncts. Based on the authors' assessment of the current literature, there is reasonable supportive evidence for pre-infiltration, fat grafting and laser skin resurfacing, which appear to be safe and effective in appropriately selected patients. Read More

Scars Burn Heal 2018 Jan-Dec;4:2059513118808773. Epub 2018 Nov 18.

Centre for Cutaneous Research, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, 4 Newark Street, London E1 2AT, UK.

Introduction: Autologous platelet-based concentrates represent increasingly popular adjuncts to a variety of medical, surgical and aesthetic interventions. Their beneficial potential rests on the ability to deliver a high concentration of growth factors to the target tissues. There are currently no reports in the literature appraising the evidence behind the use of platelet-rich plasma (PRP) in scar management. Read More

Semin Cutan Med Surg 2018 Dec;37(4):210-216

Department of Dermatology, Weill Cornell Medical College, New York, New York, USA.

The world is flat when it comes to aesthetic treatments, meaning women and men from all walks of life, regardless of culture and ethnicity or even socioeconomic status, are seeking ways to improve their appearance, prevent aging, and rejuvenate their skin. Year after year, statistics show a steady increase in people of color undergoing aesthetic treatments, with neurotoxins, fillers, laser resurfacing, and body contouring being the most sought-after procedures. When treating this cohort of patients, however, dermatologists need to be sensitized to how a patient's ethnicity affects facial structure, the tissue reaction to treatments, and patient's specific expectations for recommended therapies. Read More

Semin Cutan Med Surg 2018 Dec;37(4):226-232

Yale University School of Medicine, New Haven, Connecticut, USA.

Genitourinary syndrome of menopause (GSM), encompassing the disorders of atrophic vaginitis, urinary incontinence, and pelvic prolapse, affects the majority of postmenopausal women, as well as patients who are undergoing breast cancer treatement, post-ovarectomy, post-radiation, and breast-feeding. There is a need for better treatment options for these common conditions that adversely affect physical function and quality of life and that are often underserved by existing options. Lasers have been used to treat genitourinary tissue for over 40 years, and over the past decade, several lasers and radiofrequency devices have been developed and clinically tested for the treatment of GSM, with an accumulating body of evidence demonstrating their safety and efficacy. Read More

J Oral Maxillofac Surg 2019 Feb 27;77(2):411.e1-411.e8. Epub 2018 Oct 27.

Lecturer, Department of Oral & Maxillofacial Surgery, MGM Dental College & Hospital, Navi Mumbai, India.

Purpose: The purpose was to evaluate the clinical outcomes of laser skin resurfacing using an ultra-pulse carbon dioxide (CO) laser and manual dermabrasion with a medium-grit drywall sand screen for scar revision in adults with Fitzpatrick skin type III to V.

Materials And Methods: A total of 20 postsurgical and post-traumatic scars in individuals with Fitzpatrick skin type III to V were included in this study. Preoperative evaluation of the scars was performed by 3 blinded observers using the Manchester scar rating scale. Read More

Lasers Surg Med 2019 01 15;51(1):88-94. Epub 2018 Oct 15.

Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts.

Objective: Lidocaine acts as a local anesthetic by blocking transmembrane sodium channel permeability, but also induces the synthesis of heat shock proteins and sensitizes cells to hyperthermia. A previous study reported two cases of deep focal skin ulceration at points corresponding to depot local lidocaine injection sites after treatment with non-ablative fractional resurfacing and it was hypothesized that lidocaine had focally sensitized keratinocytes to the thermal damage of laser treatment. The objective of this study was to investigate whether lidocaine potentiates hyperthermia damage to both normal and cancerous skin cells using an in vitro model. Read More

Aesthetic Plast Surg 2018 Dec 19;42(6):1531-1539. Epub 2018 Sep 19.

Department of Plastic Surgery, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.

Background: Super-high superficial musculoaponeurotic system (SMAS) suspension and tailor tack plication are powerful facelift tools used in cases of primary facial rhytidectomy.

Technique: Thorough pre-operative patient screening and counseling are completed in an outpatient cosmetic surgery center. A super-high SMAS flap is developed by undermining and incising along a line extending from the tragus to lateral canthus and dissecting the SMAS sufficiently to induce movement of the lateral nose and the oral commissure with traction on the SMAS. Read More

Facial Plast Surg Clin North Am 2018 Nov 16;26(4):455-468. Epub 2018 Aug 16.

Division of Facial Plastic and Reconstructive Surgery, Department of Head and Neck Surgery, David Geffen School of Medicine, University of California, Los Angeles, 10833 Le Conte Avenue, CHS 62-237, Los Angeles, CA 90095, USA.

Skin resurfacing for the purpose of rejuvenation and repair continues to evolve with the development of noninvasive or minimally invasive surgical substitutes. Advances in laser therapy, microneedling, and platelet-rich plasma have reinvigorated research in wound repair and regenerative science. An overall positive clinical response toward the use of platelet-rich plasma as an adjuvant to fractional photothermolysis and percutaneous collagen induction is observed. Read More

Facial Plast Surg Clin North Am 2018 Nov 16;26(4):439-446. Epub 2018 Aug 16.

Department of Otolaryngology-Head and Neck Surgery, Weill Cornell Medicine, 1305 York Avenue, Fifth Floor, New York, NY 10021, USA. Electronic address:

Platelet preparations, including platelet-rich plasma and platelet-rich fibrin matrix, have been used to improve wound healing, recovery time, and cosmetic outcomes for facial rejuvenation. Bioactive growth factors released from platelets are the putative agents in producing a reparative tissue reaction in the treated area. Different methods of processing the patients' blood will yield different types of platelet preparations with different components and properties, and it is important to understand these differences and their potential implications. Read More

Aesthetic Plast Surg 2019 02 21;43(1):213-220. Epub 2018 Aug 21.

Department of Plastic and Reconstructive Surgery, Kangnam Sacred Heart Hospital, College of Medicine, Hallym University, 1 Singil-ro, Yeongdeungpo-gu, Seoul, 07441, Republic of Korea.

Purpose: A linear surgical scar, when located in the head and neck region, can be a significant cosmetic concern. Laser skin resurfacing with a fractional laser and a pulsed dye laser has been proven to be useful for treating such scars. As alternatives, we used a classic ablative CO laser in continuous mode with a 1-mm spot size and a 595-nm Nd:YAG laser. Read More

Lasers Med Sci 2019 Mar 3;34(2):343-351. Epub 2018 Aug 3.

Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Pran-nok Road, Bangkok, 10700, Thailand.

Therapy with light-emitting diodes (LED) has been associated with the reduction of erythema and accelerated wound healing. LED phototherapy has been used in various clinical practices including post-laser wound healing enhancement. Fractional laser resurfacing is one of the popular dermatological procedures; however, the duration and degree of downtime may limit daily life activity and studies on the effect of LED low-level light therapy (LED-LLLT) on post-ablative laser wound care are still limited. Read More

Lasers Med Sci 2019 Feb 28;34(1):79-84. Epub 2018 Jul 28.

Department of Plastic and Reconstructive Surgery, University of Rome "Tor Vergata", Tor Vergata, Rome, Italy.

Lower eyelid malposition is the most frequent and severe complication after blepharoplasty and ectropion is observed in 1% of patients after surgery. This article describes a non-surgical method to treat lower eyelid cicatricial ectropion using a non-ablative laser as an alternative to surgery. Twelve patients with unilateral or bilateral lower lid cicatricial ectropion, following surgery or trauma, underwent laser therapy from 2012 to 2016. Read More

Dermatol Surg 2018 08;44(8):1102-1108

Both authors are affiliated with the CUTIS Institute of Dermatology, Srinagar, Kashmir, India.

Background: Lasers and potent topical corticosteroids are used as therapeutic options in hypertrophic burn scars.

Objective: To assess the therapeutic effect of fractional CO2 laser resurfacing in combination with potent topical corticosteroids on hypertrophic burn scars in pediatric age group.

Methods: Ten children (5-12 years) with postburn hypertrophic scars were treated with 3 to 5 sessions of fractional CO2 laser resurfacing at 1-month intervals, and triamcinolone suspension was applied immediately after each laser session. Read More

J Cosmet Laser Ther 2019 18;21(3):145-146. Epub 2018 Jul 18.

a Department of Dermatology , Habib Thameur Hospital , Tunis , Tunisia.

Fractional photothermolysis was initially introduced by Manstein in 2004 .Fractional CO2 laser technology introduced has allowed physicians to obtain good cosmetic results with a lower rate of complications than non-fractionated ablative laser treatment. However, adverse effects may still occur. Read More

Lasers Surg Med 2018 12 17;50(10):1010-1016. Epub 2018 Jun 17.

Department of Dermatology, University Medical Centre Regensburg, 93042, Regensburg, Germany.

Background: Fractional ablative resurfacing is frequently used for treating atrophic and acne scars as well as for the early improvement of scars after surgery. No evidence-based clinical data on improving the appearance of skin grafts by fractional CO -laser resurfacing have been available so far.

Objectives: The primary outcome parameter was the adaptation of the skin graft to the surrounding skin 2, 6, and 12 months after the second laser treatment. Read More

J Burn Care Res 2018 08;39(5):811-814

UT Southwestern Division of Burns/Trauma/Critical Care, Dallas.

Our group began performing erbium-YAG 2940 wavelength fractional resurfacing of burn scar in our burn center's dedicated burn operating room (OR) in January 2016. The impact of these procedures on the performance of a mature, dedicated burn OR is unknown. All burn OR cases performed between January 1, 2015 and December 31, 2015 served as a pre-laser (PRE-LSR) historical control. Read More

Am J Clin Dermatol 2018 Aug;19(4):459-477

Department of Dermatology, Medical School of Jundiaí, São Paulo, Brazil.

Background: Modalities for atrophic acne scarring can be classified depending upon the needs they satisfy; that is, resurfacing, lifting/volumization, tightening, or surgical removal/movement of tissue that is required for correction. A plethora of treatment options have resulted from the need to treat various acne scar types, variability of responses noted in various skin types, and increasing popularity of minimally invasive modalities. Still, there is a lack of consensus guidelines on treatment or combination therapies for various clinical scenarios. Read More

Dermatol Surg 2018 08;44(8):1109-1114

Universidade Federal do Rio de Janeiro, Faculdade de Medicina, Serviço de Anatomia Patológica-Brasil, Rio de Janeiro, Brazil.

Background: Expression of p53 by keratinocytes may be important in the pathogenesis of skin cancer induced by ultraviolet light.

Objective: We used side-by-side nonablative and ablative erbium fractional laser resurfacing to assess the effects on expression of p53 by facial keratinocytes.

Methods: Ten female patients (age range, 50-63 years) with Fitzpatrick skin Types I-IV and clinical signs of photoaging underwent erbium fractional laser resurfacing (nonablative, 1,540-nm; ablative, 2,940-nm) on opposite sides of the face. Read More

Burns 2018 08 4;44(5):1100-1105. Epub 2018 Apr 4.

UT Southwestern Division of Burns/Trauma/Critical Care, Dallas, TX, United States. Electronic address:

Objective: Fractional laser therapy is a new treatment with potential benefit in the treatment of burn scars. We sought to determine patient satisfaction after burn scar treatment with the Erbium-Yag laser.

Methods: We performed a telephone survey of all patients who underwent fractional resurfacing of burn scars with the Erbium-Yag 2940 wavelength laser at Parkland Hospital from 01/01/2016 to 05/01/2017. Read More

J Biol Regul Homeost Agents 2018 Jan-Feb;32(2 Suppl. 1):159-165

Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Italy.

Scars are a very common condition of the general population and can have a profound impact on the psyche of the patient such as low self-esteem and feelings of psychosocial isolation. Various therapeutic approaches have been proposed for improving the clinical appearance of scars. Fractional mode of ablative and non-ablative lasers has become a novel strategy for the treatment of scars. Read More

Int J Dermatol 2018 Apr 12;57(4):480-487. Epub 2018 Feb 12.

Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Pathumwan, Bangkok, Thailand.

Proven as effective acne scar treatment, ablative fractional carbon dioxide (AFCO ) laser requires post-laser wound healing care. MAS063DP is a multicomponent nonsteroidal anti-inflammatory moisturizer for effective post-laser treatment. This study compares the efficacy of MAS063DP and 0. Read More

Facial Plast Surg 2018 Apr 5;34(2):205-219. Epub 2018 Jan 5.

Department of Dermatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Ablative fractional carbon dioxide laser resurfacing is a well-established treatment for acne scars. However, there are limited consensus and guidelines regarding the procedure, such as its treatment plan, efficacy, and safety. In this study, we performed a systematic review to assess the efficacy and safety of the fractional carbon dioxide laser treatment procedure, and to provide evidence-based recommendations concerning its practical use on atrophic acne scars. Read More

Pediatr Dermatol 2018 Mar 20;35(2):268-270. Epub 2017 Dec 20.

Division of Pediatric and Adolescent Dermatology, Rady Children's Hospital and University of California at San Diego, San Diego, CA, USA.

Keloid scars are benign proliferations of fibrous tissue and collagen that usually occur in response to cutaneous injury. Many treatment modalities have been described in the literature, with variable rates of recurrence and no clear consensus. Keloids remain a therapeutic challenge to patients and physicians alike. Read More