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J Cosmet Laser Ther 2021 May 4:1-3. Epub 2021 May 4.

Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Minimally invasive fractional rejuvenation was developed to overcome the drawbacks of the traditional ablative laser. The Fotona 4D laser is one of these lasers used for face lifting. This laser uses two wavelengths such as Nd-YAG 1064 and Er-YAG 2940 nm in four different modes of non-ablative and ablative fractional laser to induce bulk heating in different tissue layers of facial skin. Read More

Life (Basel) 2021 Apr 17;11(4). Epub 2021 Apr 17.

Department and Graduate Institute of Biology and Anatomy, National Defense Medical Center, Taipei 114, Taiwan.

Background: During ablative fractional resurfacing (AFR) laser therapy, thermal damage to the skin is inevitable, resulting in inflammatory responses and small wounds. Corticosteroids are known for their anti-inflammatory effect. However, inappropriate application of corticosteroids carries the risk of delayed wound healing. Read More

Aesthetic Plast Surg 2021 Apr 21. Epub 2021 Apr 21.

Pharmaceutical Research Group, Faculty of Health, School of Allied Health, Education, Medicine and Social Care, Anglia Ruskin University, Bishops Hall Lane, Chelmsford, CM1 1SQ, UK.

Background: Scarring can jeopardize the final result of plastic surgeries. Deep dermal injuries activate dermal fibroblasts that produce excessive amount of collagen and inflammatory cytokines and growth factors, which contributes to increased fibrous tissue and scarring tissue formation.

Objectives: The aim of this early study, double-blind, prospective, randomised clinical trial was to investigate the use of laser-assisted drug delivery (LADD) for scar improvement to support the establishment of LADD as standard therapy modality and to indicate suitable drugs for dermal administration. Read More

Lasers Surg Med 2021 Apr 1. Epub 2021 Apr 1.

Faculty of Mechanical Engineering, University of Ljubljana, Askerceva 6 SI-1000, Ljubljana, Slovenia.

Background And Objectives: Recently, several minimally invasive gynecological, ENT and esthetic procedures have been introduced that are based on delivering "smooth" sequences of Er:YAG laser pulses to cutaneous or mucosal tissue at moderate cumulative fluences that are not only below the ablation threshold but typically also do not require local anesthesia.  To explain the observed clinical results using "smooth-resurfacing," it has been suggested that in addition to the direct heat injury to deeper-lying connective tissues, there is an additional mechanism based on indirect triggering of tissue regeneration through short-exposure, intense heat shocking of epithelia. The goal of this study is to improve understanding of the complex dynamics of the exposure of tissues to a series of short Er:YAG laser pulses, during which the thermal exposure times transition from extremely short to long durations. Read More

J Drugs Dermatol 2021 01;20(1):23-29

Background: Absorbable suspension sutures are an effective nonsurgical modality for correction of ptosis and tissue repositioning in the face and neck. The PLLA/PLGA suture is entirely absorbable and has a dual effect in that it both lifts tissues and induces collagenesis, thereby restoring contour. In clinical practice, nonsurgical modalities are rarely used in isolation, and combination treatments with fillers, neuromodulators, lipolysis, and energy-based devices are common. Read More

Semin Plast Surg 2020 Nov 24;34(4):305-313. Epub 2020 Dec 24.

Otolaryngology and Facial Plastic Surgery Associates, Fort Worth, Texas.

The process of scar formation is a sequela of the healing following soft tissue injury extending to, or through, the reticular dermis. Scars, within the head and neck in particular, may be physically disfiguring with resultant psychosocial implications. Mitigation of excessive scar formation during the healing process following surgery, or in the setting of trauma, begins with meticulous soft tissue handling and reconstructive technique. Read More

Lasers Surg Med 2021 01 8;53(1):115-118. Epub 2020 Nov 8.

SkinCare Physicians, Chestnut Hill, Massachusetts.

Introduction: The COVID-19 pandemic requires us all to re-evaluate aesthetic practices to ensure optimal patient safety during elective procedures. Specifically, energy-based devices and lasers require special consideration, as they may emit plume which has been shown to contain tissue debris and aerosolized biological materials. Prior studies have shown transmission of viruses and bacteria via plume (i. Read More

Acta Derm Venereol 2020 Nov;100(18):adv00310

Oaro Dermatology Institute, Seoul, Korea.

A variety of applications of human adipose tissue stem cell-derived exosomes have been suggested as novel cell-free therapeutic strategies in the regenerative and aesthetic medical fields. This study evaluated the clinical efficacy and safety of adipose tissue stem cell-derived exosomes as an adjuvant therapy after application of fractional CO2 laser for acne scars. A 12-week prospective, double-blind, randomized, split-face trial was performed. Read More

Dermatol Ther 2020 11 15;33(6):e14270. Epub 2020 Sep 15.

Department of Dermatology, Inonu University, Malatya, Turkey.

Erbium: Yttrium-aluminum-garnet laser (Er: YAG) treatment has been used in resurfacing the acne scars for a long time; however, we could not find any study reporting the recovery rates after each session of the treatment. In this study, we aimed to report the improvement rates after each session. We retrospectively analyzed the data of 35 patients with acne scars treated with fractional ablative Er: YAG laser. Read More

Int Urogynecol J 2020 Dec 11;31(12):2473-2484. Epub 2020 Aug 11.

Centre for Surgical Technologies, Group Biomedical Sciences, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.

Introduction And Hypothesis: Er:YAG laser is frequently used in dermatology and gynecology. Clinical studies document high satisfaction rates; however, hard data on the effects at the structural and molecular levels are limited. The aim of this systematic review was to summarize current knowledge about the objective effects of non-ablative Er:YAG laser on the skin and vaginal wall. Read More

Dermatol Surg 2020 12;46(12):1577-1582

Department of Dermatology and Oncology, University of Rochester Medical Center, Rochester, New York.

Background: Thermal burn scars can have catastrophic impact on the quality of life and personal image, and over time can lead to profound physical and psychological debilitation. There are no established treatments to significantly improve burn scars.

Objective: To demonstrate the safety, efficacy, and tolerability of fractionally ablative Er:YAG resurfacing of mature burn scars. Read More

Lasers Surg Med 2020 12 29;52(10):940-951. Epub 2020 Apr 29.

DeLozier Cosmetic Surgery Center, 209 23rd Ave N, Nashville, Tennessee, 37203.

Background And Objectives: A novel helium plasma device was evaluated for efficacy and safety for dermal resurfacing (ClinicalTrials.gov Identifier: NCT03286283). The helium plasma device delivers energy in a controlled, bimodal fashion that when compared with the nitrogen plasma predicate device in a porcine animal model demonstrated a more limited depth of thermal effect but a greater skin tissue contraction. Read More

J Altern Complement Med 2020 Jun 20;26(6):529-536. Epub 2020 Apr 20.

Preclinical Pharmacokinetics and Interspecies Scaling for Drug Development Research Unit, Chulalongkorn University, Bangkok, Thailand.

, a medicinal plant, has been used traditionally to promote wound healing. Its efficacy on promoting postlaser resurfacing wound healing is lacking. Thirty individuals with facial acne scars underwent a treatment with 2940 nm Er:YAG laser. Read More

Plast Reconstr Surg Glob Open 2020 Feb 26;8(2):e2640. Epub 2020 Feb 26.

Swanson Center, Leawood, KS.

Background: Despite their name, "short scar" procedures leave scars in the temples and the postauricular scar often requires extension. Redraping the orbicularis muscle for periorbital rejuvenation increases the risk of facial nerve injury. This retrospective cohort study was undertaken to clinically evaluate a surgical approach that eliminates the temporal incision. Read More

Lasers Surg Med 2020 10 14;52(8):788-798. Epub 2020 Jan 14.

Institute of Biomedical Optics, University of Luebeck, Luebeck, 23562, Germany.

Background And Objectives: A recent generation of 5,500 nm wavelength carbon monoxide (CO) lasers could serve as a novel tool for applications in medicine and surgery. At this wavelength, the optical penetration depth is about three times higher than that of the 10,600 nm wavelength carbon dioxide (CO ) laser. As the amount of ablation and coagulation is strongly influenced by the wavelength, we anticipated that CO lasers would provide extended coagulation zones, which could be beneficial for several medical applications, such as tissue tightening effects after laser skin resurfacing. Read More

Burns 2020 02 14;46(1):65-74. Epub 2019 Dec 14.

Burns Unit, Concord Repatriation General Hospital, Sydney, Australia; ANZAC Research Institute, Concord Repatriation General Hospital, Sydney, Australia; University of Sydney, Sydney, Australia.

Background: Reconstructive surgery remains the main approach to address burn scar contractures. Ablative fractional resurfacing is an increasingly popular tool for severe burn scar management, but its effect on overall burns reconstructive case-mix, operating time and patterns of hospital admission have not been reported.

Methods: Retrospective analysis of hospital administrative data from September 2013 to June 2017 was performed evaluating these effects of ablative fractional CO laser (CO-AFL). Read More

Facial Plast Surg Clin North Am 2020 Feb;28(1):17-28

Laserplast SrL StP, Piazza Eleonora Duse 2 Milano, Republic of Italy; R&D Department, Swansea Bay University Health Board and the Welsh Centre for Burns and Plastic Surgery, Moriston Hospital, Swansea SA6 6NL, United Kingdom.

Fractional CO procedures are an established, safe and effective armamentarium for managing skin rejuvenation and scarring. Very short-pulse-duration devices offer a very high ablated volume/ablated surface ratio, inducing a controlled thermal damage. With this kind of device, each procedure can be customized on the features of the skin of each patient. Read More

Aesthet Surg J 2020 08;40(9):938-947

Scheie Eye Institute, Division of Oculoplastics, Philadelphia, PA.

Background: The tear trough is a prominent structure of the midface. Many surgical and nonsurgical techniques have been devised to efface this feature.

Objectives: The aim of this study was to define an aesthetically pleasing tear trough and understand the effect of various surgical procedures on its appearance. Read More

Dermatol Surg 2021 02;47(2):301-303

SkinCare Physicians, Chestnut Hill, Massachusetts.

Plast Reconstr Surg Glob Open 2019 Jun 14;7(6):e2075. Epub 2019 Jun 14.

Dallas Plastic Surgery Institute, Dallas, Texas, USA.

Face-lift techniques have evolved beyond the concept of lifting and now include incorporating superficial and deep filling of facial fat compartments to address volume deflation and aging. In addition to traditional face-lift methods involving the excision and tightening of skin and the underlying soft tissues, the following ancillary procedures have become paramount in achieving an optimal result: blending the lid-cheek junction; chin augmentation; lobule augmentation; hand rejuvenation; perioral rejuvenation; chemical peels; and laser resurfacing. We presented a summary of these integral techniques. Read More

Skin Therapy Lett 2019 Sep;24(5):1-6

Dr. Jason Emer, West Hollywood, CA, USA

Platelet-rich plasma (PRP) is an autologous serum containing high concentrations of platelets and growth factors. PRP continues to evolve as an important treatment modality with many applications in dermatology, particularly in the areas of hair restoration, skin rejuvenation, acne scars, dermal augmentation, and striae distensae. Furthermore, combining PRP with laser therapies, microneedling, dermal fillers, and autologous fat grafting produces synergistic effects, leading to improved aesthetic results. Read More

Aesthet Surg J 2020 10;40(11):1253-1262

Dr Nazerali is an Attending Physician, Division of Plastic Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA.

Background: Google Trends (GT) provides cost-free, customizable analyses of search traffic for specified terms entered into Google's search engine. GT may inform plastic surgery marketing decisions and resource allocation.

Objectives: The aim of this study was to determine GT's utility in tracking and predicting public interest in nonsurgical cosmetic procedures and to examine trends over time of public interest in nonsurgical procedures. Read More

J Ayub Med Coll Abbottabad 2019 Jul-Sep;31(3):336-339

Jinnah Burn and Reconstructive Surgery Center, Allama Iqbal Medical College, Lahore, Pakistan.

Background: Acne effects 80-90% of teenage population all around the world. Resulting scars can lead to facial disfigurement and psychological issues in affected population. To counter this problem many treatment options have been tried including resurfacing lasers, dermabrasion, peeling, fillers, platelet rich plasma therapy etc. Read More

Aesthet Surg J 2020 07;40(8):892-899

Division of Plastic Surgery, Le Belvedere Hospital, Mont Saint Aignan, France.

Background: Improvements in skin erythema and elasticity have been observed with topical application of platelet-rich plasma after fractional laser (FXD) treatment. Injections of nanofat via small needles into the dermis improves tissue thickness, discoloration and wrinkle depth.

Objectives: The aim of this study was to evaluate improvements in skin following a nonablative FXD treatment combined with the application of a novel topical nanofat biocrème, called neo-U. Read More

Dermatol Ther 2019 11 7;32(6):e13084. Epub 2019 Oct 7.

Department of Dermatology, The Affiliated Hospital of North Sichuan Medical College, Nanchong, China.

Fractional ablative carbon dioxide laser resurfacing is a frontline treatment for acne scars. It creates multiple microscopic treatment zones to accelerate the collagen formation and the healing process of reepithelialization, according the principle of fractional photothermolysis. At present, the fractional CO laser with a wavelength of 10,600 nm is commonly used in the field of cosmetology and clinical therapies for various skin diseases, and it can effectively improve skin regeneration and scar formation. Read More

Biomed Res Int 2019 1;2019:6952649. Epub 2019 Jul 1.

Department of Technology Design/Laboratory of Bone Implants Research and Design, Institute of Mechanical Technology, Poznan University of Technology, Piotrowo Street 3, 60-965 Poznan, Poland.

Resurfacing hip and knee endoprostheses are generally embedded in shallow, prepared areas in the bone and secured with cement. Massive cement penetration into periarticular bone, although it provides sufficient primary fixation, leads to the progressive weakening of peri-implant bone and results in failures. The aim of this paper was to investigate in an animal model the first biomimetic fixation of components of resurfacing arthroplasty endoprostheses by means of the innovative multispiked connecting scaffold (MSC-Scaffold). Read More

Am J Clin Dermatol 2019 Oct;20(5):683-690

Advanced Dermatology, Lincolnshire and Glencoe, IL, USA.

Over the past 30 years, the treatment of acne scars has undergone changes that have been significantly influenced by the concurrent development of new devices. The advent of fractional resurfacing lasers was a watershed moment for acne scarring therapy. The author recounts a career history of considerations of acne scarring treatments as well as the literature supporting the experiences causing changes in practice. Read More

Facial Plast Surg 2019 Jun 12;35(3):248-255. Epub 2019 Jun 12.

Department of Otolaryngology - Head and Neck Surgery, Rutgers New Jersey Medical School, Summit, New Jersey.

Laser technology continues to increase in popularity and expand treatment options for patients with common but challenging skin conditions including facial telangiectasias, facial aging, striae distensae, and acne scars. Facial telangiectasias have been estimated to occur in tens of millions of people worldwide. The 585-nm laser was the first to follow the principle of selective photothermolysis for the treatment of cutaneous vascular lesions, but it caused significant postoperative purpura. Read More