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Arch Soc Esp Oftalmol (Engl Ed) 2022 Mar 27;97(3):172-175. Epub 2021 Feb 27.

Unidad de Uveítis, Departamento de Oftalmología, Hospital de León, Instituto de Biomedicina (IBIOMED), Universidad de León, Complejo Asistencial Universitario de León, León, Spain. Electronic address:

We describe two cases of ocular complications secondary to Diode laser assisted eyebrow epilation. Both included patients were women who underwent an eyebrow epilation procedure with Diode laser. A few hours after the procedure they started complaining with photophobia and blurred vision. Read More

J Lasers Med Sci 2021 20;12:e21. Epub 2021 May 20.

Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Laser-assisted hair removal is widely used by a large number of patients complaining of unwanted hair. However, little is known about the effect of varying the pulse duration on clinical results and side effects. This study aimed to investigate the effectiveness of hair removal using an alexandrite laser with different pulse durations. Read More

Lasers Med Sci 2022 Mar 13;37(2):913-918. Epub 2021 May 13.

Dermatology, Venereology and Andrology, Faculty of Medicine, Benha University, Banha, Egypt.

Complications of laser hair reduction should be classified not only to skin and ocular complications but to skin, ocular, and scalp hair complications. Do not forget the plumes. Awareness about laser dangers is very critical. Read More

Dermatol Ther 2021 03 28;34(2):e14859. Epub 2021 Feb 28.

Faculty of Medicine, Department of Dermatology, Zagazig University, Zagazig, Egypt.

Pseudofolliculitis barbae (PFB) presents as chronic inflammation of the beard area that affect males but also females may affect if have coarse hair. Its treatment can be challenging. Laser-assisted hair removal causes miniaturization of hair shafts which are the principal contributors to inflammation in PFB. Read More

Sex Transm Dis 2021 Feb;48(2):e30-e31

Infectious Diseases Departments, Centro Hospitalar Universitário do Porto (CHUP), Porto, Portugal.

Abstract: We report a case of perianal reactivation of herpes simplex virus type 2 in a 27-year-old man, who was HIV positive with good immunovirological status, after a laser-assisted (alexandrite) hair removal session. We discuss the clinical and laboratory features and the role of prophylaxis with antivirals, particularly in certain patients such as immunocompromised ones. Read More

Arch Soc Esp Oftalmol (Engl Ed) 2020 Dec 6. Epub 2020 Dec 6.

Unidad de Uveítis, Departamento de Oftalmología, Hospital de León. Instituto de Biomedicina (IBIOMED), Universidad de León. Complejo Asistencial Universitario de León, León, España. Electronic address:

We describe two cases of ocular complications secondary to Diode laser assisted eyebrow epilation. Both included patients were women who underwent an eyebrow epilation procedure with Diode laser. A few hours after the procedure they started complaining with photophobia and blurred vision. Read More

Dermatol Ther 2021 01 16;34(1):e14599. Epub 2020 Dec 16.

Section of Dermatology, Department of Medicine and Surgery, University of Parma, Parma, Italy.

This retrospective cohort study regarding hair removal procedures considers all the data collected in three different clinical centers from 2017 to 2019. The device used to perform the treatments was composed of an Alexandrite 755 nm and an Nd:YAG 1064 nm laser, that delivered both wavelengths in a blended simultaneous emission (Thunder MT, Quanta System, Samarate, Italy). The improvement evaluated after five sessions of treatment by an external referee was: 83. Read More

J Lasers Med Sci 2020 15;11(2):132-137. Epub 2020 Mar 15.

The Section of Professional Cosmetology, The Faculty of Motor Rehabilitation, The University of Physical Education in Krakow, Poland.

As hair removal has become most popular in aesthetics, the management of its side effects is crucial for every practitioner. Available studies describe the effectiveness of the diode laser hair removal for all skin types according to the Fitzpatrick scale independently, but the question of the occurrence of side effects and adverse effects remains unanswered. This study aims to illustrate aspects of side effects for patients of various ethnicities and the impact of those on the effectiveness of the treatment. Read More

Am J Emerg Med 2019 11 24;37(11):2119.e1-2119.e2. Epub 2019 Aug 24.

Department of Emergency Medicine, Maimonides Medical Center, Brooklyn, NY, USA.

This is the case of a 23-year-old female with a past medical history of ADHD and Depression who was evaluated in the emergency department for perioral cyanosis and hypoxia after application of the eutectic mixture of lidocaine and prilocaine (EMLA) local anesthetic prior to a laser-assisted hair removal procedure. This report illustrates a case of methemoglobinemia which is a rare but significant complication of topical anesthetic use. Read More

Photodermatol Photoimmunol Photomed 2019 Sep 5;35(5):313-317. Epub 2019 May 5.

Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Background: In recent years, there was a rise in ocular injuries secondary to cosmetic laser-assisted hair removal.

Purpose: To assess the level of adherence to optical safety guidelines during laser-assisted hair removal performed by nurses or physicians in private practice.

Methods: A cross-sectional study was conducted at thirty-one private laser-assisted hair removal clinics. Read More

J Cosmet Laser Ther 2019 1;21(2):69-70. Epub 2018 Jun 1.

b Pathology Department , Ankara University.

Laser is the most efficient and popular method in hair removal. The most common side effects of laser assisted hair removal are pain, erythema, edema, hypopigmentation, hyperpigmentation, blistering, crusting, erosions, purpura, folliculitis, and scar formation ( 1 ). Herein, for the first time we describe a case of lichen sclerosus (LS) following hair removal with long pulsed 1064 nm Nd:YAG laser therapy. Read More

Lasers Surg Med 2018 09 30;50(9):893-901. Epub 2018 May 30.

Laser and Skin Surgery Center of Northern California, Sacramento Lumenis LTD, Sacramento, California.

Objective: The purpose of this study was to determine the efficacy and safety of a 1060 nm diode laser system with multiple handpieces for permanent hair reduction.

Study Design: An open-label, prospective, multi-center study of adult subjects (≥18 years old) of any skin type, having dark brown or black hairs at the areas to be treated and seeking to permanently remove hair underwent six treatment sessions, at 4 to 6 weeks intervals with either a 1060 nm chilled sapphire tip or seven treatment sessions, at 6 weeks interval with a large spot vacuum based handpiece.

Methods: Subjects received treatments on various body areas using chilled sapphire tip or large spot size vacuum-assisted handpiece. Read More

Int J Legal Med 2019 May 21;133(3):843-846. Epub 2018 May 21.

Centre antipoison et de toxicovigilance de Paris, hôpital Fernand-Widal, Paris, France.

Background: Eutectic mixtures of lidocaine and prilocaine are used during painful dermatological procedures. Poisoning is rarely reported in adults.

Material And Method: We report three cases of women who experienced lidocaine and prilocaine poisoning after laser-assisted hair removal. Read More

J Drugs Dermatol 2018 Apr;17(4):413-418

Introduction: A variety of topical anesthetic creams are available to reduce pain associated with dermatological procedures. Pliaglis is a self-occluding eutectic mixture of lidocaine and tetracaine.

Study Objectives: To evaluate the post-marketing safety profile of Pliaglis and efficacy in terms of pain reduction, product satisfaction, and daily practice use prior to pre-defined dermatological procedures. Read More

Annu Int Conf IEEE Eng Med Biol Soc 2017 Jul;2017:604-607

Laser-assisted hair removal devices aim to remove body hair permanently. In most cases, these devices irradiate the whole area of the skin with a homogenous power density. Thus, a significant portion of the skin, where hair is not present, is burnt unnecessarily causing health risks. Read More

J Cosmet Laser Ther 2018 Jun 8;20(3):140-144. Epub 2017 Dec 8.

a Department of Dermatology , Frimley Park hospital NHS Foundation Trust , Camberley , UK.

Poly cystic ovarian syndrome (PCOS) has been described as the common diagnosis for hirsutism in women. Facial hirsutism is by far the most distressing symptom of hyperandrogenism in women with PCOS. A statistically significant improvement in psychological well-being has been reported in patients with PCOS allocated for laser-assisted hair removal. Read More

J Drugs Dermatol 2017 Sep;16(9):893-898

BACKGROUND The 800 nm long-pulsed diode laser machine is safe and effective for permanent hair reduction. Traditionally, most long-pulsed diode lasers used for hair removal had a relatively small spot size. Recently, a long-pulsed diode laser with a large spot size and vacuum assisted suction handpiece was introduced. Read More

Photomed Laser Surg 2017 Jun;35(6):317-323

5 Department of Biomedical Engineering, Seoul National University College of Medicine , Seoul, Korea.

Background And Objective: Many laser devices have been developed over the past decades for various skin conditions. However, variations in the technical skill of physicians for laser skin treatment delivery have not yet been evaluated. This study evaluates the differences in omission and overlap percentages during simulated laser hair removal treatments among physicians at two clinics. Read More

J Dtsch Dermatol Ges 2017 May;15(5):487-496

Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Denmark.

Recent developments (new wavelengths, treatment concepts, and combinations) in the field of lasers, intense pulsed light (IPL), LED, as well as new energy and light sources have opened up new therapeutic options that extend beyond mere aesthetic indications. Thus, while fractional lasers used to be employed to merely treat wrinkles, the same devices - in the context of laser-assisted drug delivery - have now become important tools in the treatment of scars, field cancerization, and epithelial tumors. The requirements posed to physicians, both with respect to establishing the indication and conducting treatment, have been growing along with the increase in technological complexity as well as the rising number of comorbidities and comedications in a patient population that continues to age. Read More

Can J Ophthalmol 2017 Apr 9;52(2):e71-e75. Epub 2017 Jan 9.

King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia. Electronic address:

Purpose: The aim of this study was to describe the clinical manifestations and outcomes of 4 patients who had sustained eye injury during alexandrite laser-assisted hair removal.

Methods: This was a retrospective case series of 4 patients who presented to 2 tertiary eye care hospitals over 2 years. Data on ophthalmic examination, spectral domain optical coherence tomography (Heidelberg Engineering, Heidelberg, Germany), and fundus fluorescein angiography were collected. Read More

J Drugs Dermatol 2016 Nov;15(11):1427-1434

Laser-based photoepilation of dark skin types demands a delicate combination of appropriate light wavelengths and spot size to achieve optimal epidermal-to-follicular energy absorption ratios. This prospective study assessed the axillary, arm, thigh, and back hair clearing ef cacy of the LightSheer In nity 1060 nm diode laser in 10 Fitzpatrick skin type IV-V patients. Each area was treated up to ve times, at 4-6-week intervals, after which immediate skin responses and adverse events were recorded. Read More

Photomed Laser Surg 2017 Feb 3;35(2):116-121. Epub 2016 Nov 3.

5 Department of Biomedical Engineering, College of Medicine, Seoul National University , Seoul, Korea.

Objective: We aimed to develop and validate a novel computer-assisted automated hair counting system for the quantitative evaluation of laser hair removal (LHR).

Methods: We developed a computer-aided image processing system to count hairs on shaved skin and validated its performance through clinical trials. Five volunteers of Fitzpatrick skin type III-IV volunteered and were tested on both thighs. Read More

Photomed Laser Surg 2016 Jan 23;34(1):42-9. Epub 2015 Nov 23.

5 Department of Biomedical Engineering, Seoul National University College of Medicine , Seoul, Korea.

Objective: This study aims to improve the performance of an automatic laser hair removal (LHR) system by applying an algorithm that considers the curve and slant of the skin surface.

Background Data: In an earlier research, a robot-assisted LHR system has been developed and validated for an almost flat skin or a relatively smooth curved part of the skin. For practical clinical applications, the feature of the robot-assisted LHR system is extended for real curved skins. Read More

Int Med Case Rep J 2015 7;8:177-9. Epub 2015 Sep 7.

Department of Ophthalmology, Kadıköy Medipol Hospital, Istanbul Medipol University, Istanbul, Turkey.

Ocular tissues are known to be sensitive to damage from exposure to laser emissions. This study reports the case of a female patient with acute unilateral anterior uveitis caused by alexandrite laser-assisted hair removal of the eyebrows. We report a 38-year-old female who presented with unilateral eye pain, redness, and photophobia after receiving alexandrite (755 nm) laser epilation of both eyebrows. Read More

Photomed Laser Surg 2015 Oct 8;33(10):509-16. Epub 2015 Sep 8.

5 Department of Biomedical Engineering, Seoul National University College of Medicine , Seoul, Korea.

Objective: This study aimed to evaluate the number of laser irradiation sessions, process duration, and hair removal rate required for robot-assisted automatic versus physician-directed laser hair removal.

Background Data: This research group previously developed and tested an automatic laser hair removal (LHR) system to provide uniform laser treatment distribution.

Methods: Six subjects 20-40 years of age, with skin types III-IV completed this study. Read More

Cornea 2015 Jan;34(1):101-2

Department of Ophthalmology, Süleyman Demirel University, Faculty of Medicine, Isparta, Turkey.

Purpose: Laser-assisted epilation of eyebrow hair has become a common practice, but a number of ocular complications can occur. We report the cases of 2 patients who had unilateral anterior uveitis after having undergone laser removal of eyebrow hair.

Methods: This report describes 2 patients who experienced eye pain, photophobia, redness, and edema after undergoing alexandrite (755 nm) laser epilation of the eyebrow area while not wearing protective eyewear or a corneal shield. Read More

Photomed Laser Surg 2014 Nov 24;32(11):633-41. Epub 2014 Oct 24.

1 Interdisciplinary Program for Bioengineering, Seoul National University , Seoul, Korea.

Unlabelled: Abstract Background and Objective: The robot-assisted automatic laser hair removal (LHR) system is developed to automatically detect any arbitrary shape of the desired LHR treatment area and to provide uniform laser irradiation to the designated skin area.

Methods: For uniform delivery of laser energy, a unit of a commercial LHR device, a laser distance sensor, and a high-resolution webcam are attached at the six axis industrial robot's end-effector, which can be easily controlled using a graphical user interface (GUI). During the treatment, the system provides real-time treatment progress as well as the total number of "pick and place" automatically. Read More

Adv Biomed Res 2014 31;3:110. Epub 2014 Mar 31.

Skin and Stem Cell Research Center, Department of Dermatology, Tehran University of Medical Sciences, Tehran, Iran.

Background: Lidocaine 7%-tetracaine 7% is one of the combinations recently offered for performing laser-assisted hair removal. The aim of this study was to compare the effects of this combination with placebo on the side effects of laser-assisted hair removal.

Materials And Methods: This clinical trial was carried out on 110 women who referred to Isfahan Spadana laser clinic for laser-assisted hair removal. Read More

Lasers Surg Med 2014 Apr;46(4):270-4

Background & Objective: Laser hair removal has become an increasingly popular method to remove unwanted or excessive hair. We have assessed the relative efficacy and discomfort associated with competing hair removal techniques, namely a high average power 810 nm diode laser using an “in-motion” technique with a market-leading 810 nm device with a single-pass vacuum-assisted technique. This study has determined the long-term (6-12 months) hair reduction efficacy and the relative pain induction intensities of these devices. Read More

Eur J Dermatol 2014 May-Jun;24(3):391-2

Department of Pathology, Medical Research Division, National Research Centre, Egypt.