20,039 results match your criteria Laryngoscope[Journal]


3D-printed, externally-implanted, bioresorbable airway splints for severe tracheobronchomalacia.

Laryngoscope 2019 Feb 22. Epub 2019 Feb 22.

Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan.

Objectives/hypothesis: To report the clinical safety and efficacy of three-dimensional (3D)-printed, patient-specific, bioresorbable airway splints in a cohort of critically ill children with severe tracheobronchomalacia.

Study Design: Case series.

Methods: From 2012 to 2018, 15 subjects received 29 splints on their trachea, right and/or left mainstem bronchi. Read More

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http://dx.doi.org/10.1002/lary.27863DOI Listing
February 2019

Add-on probiotics in patients with persistent allergic rhinitis: A randomized crossover clinical trial.

Laryngoscope 2019 Feb 22. Epub 2019 Feb 22.

Department of Otolaryngology, Guilan University of Medical Sciences, Rasht, Iran.

Objectives: Current medications for allergic rhinitis (AR) may have undesirable side effects that could affect quality of life (QoL). Probiotics could be an alternative in these patients. The aim of this study was to assess the impact of add-on probiotics on symptoms and QoL of patients. Read More

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http://dx.doi.org/10.1002/lary.27858DOI Listing
February 2019

Recurrence patterns of sinonasal cancers after a 5-year disease-free period.

Laryngoscope 2019 Feb 22. Epub 2019 Feb 22.

Department of Otorhinolaryngology-Head and Neck Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.

Objectives/hypothesis: Sinonasal cancers are rare but have a poor prognosis. Most previous studies of these cancers have focused on 5-year disease-free survival, but recurrences are also known to occur after this period. We examined the post-5-year recurrence patterns in sinonasal cancer patients by histologic type to determine the indicators for extended and close follow-up requirements. Read More

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http://dx.doi.org/10.1002/lary.27866DOI Listing
February 2019

Hemodynamic and pharmacokinetic analysis of oxymetazoline use during nasal surgery in children.

Laryngoscope 2019 Feb 20. Epub 2019 Feb 20.

Department of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, Ohio, U.S.A.

Objectives/hypothesis: Oxymetazoline is an α-adrenergic agonist that is commonly used as a topical hemostatic agent in the operating room during ear, nose, and throat surgery. There are limited data on oxymetazoline pharmacokinetics in children who undergo general anesthesia. We assessed the hemodynamic effects and systemic absorption of topically applied oxymetazoline in children undergoing various nasal procedures. Read More

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http://dx.doi.org/10.1002/lary.27760DOI Listing
February 2019
1 Read

A nomogram to predict osteoradionecrosis in oral cancer after marginal mandibulectomy and radiotherapy.

Laryngoscope 2019 Feb 20. Epub 2019 Feb 20.

Department of Otolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital, Kwei-Shan, Taiwan.

Objective: There is no useful tool to clinically predict the occurrence of osteoradionecrosis (ORN) of the mandible quantitatively. The aim was to investigate the risk factors, including different modalities of radiotherapy, for developing mandibular ORN in patients undergoing marginal mandibulectomy and postoperative radiotherapy.

Methods: Between January 2006 and December 2012, 167 subjects who underwent marginal mandibulectomy and postoperative radiotherapy with different modalities were enrolled. Read More

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http://dx.doi.org/10.1002/lary.27870DOI Listing
February 2019

Epidemiology and resource utilization of ludwig angina ED visits in the United States 2006-2014.

Laryngoscope 2019 Feb 20. Epub 2019 Feb 20.

Department of Surgery, Division of Otolaryngology/Head & Neck Surgery, Howard University College of Medicine, Washington, District of Columbia, U.S.A.

Objectives: Ludwig angina is a potentially lethal submandibular space infection. We aim to describe the epidemiological characteristics of Ludwig angina patients presenting to the emergency department (ED) and to examine outcomes and resource utilization to determine their burden on ED and hospitals.

Methods: Using the Nationwide Emergency Department Sample database, a nationally representative all-payer database, we retrospectively reviewed all ED visits between 2006 and 2014 for patients admitted with a primary diagnosis of Ludwig angina (International Classification of Diseases, Ninth Revision, 528. Read More

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http://dx.doi.org/10.1002/lary.27734DOI Listing
February 2019

Multicenter randomized crossover trial evaluating the provox luna in laryngectomized subjects.

Laryngoscope 2019 Feb 20. Epub 2019 Feb 20.

Netherlands Cancer Institute, Amsterdam, New Zealand.

Objectives: The aim of this study was to compare the relative compliance and the dermatological and pulmonary outcomes when the Provox Luna system (Atos Medical, Malmö, Sweden) is added during the night to the usual tracheastoma care of laryngectomized subjects.

Methods: This was a multicenter randomized crossover trial conducted in the Netherlands Cancer Institute, Erasmus Medical Center, and Maastricht University Medical Center in The Netherlands. The study included 46 laryngectomized subjects with prior heat and moisture exchanger (HME) and adhesive experience. Read More

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http://doi.wiley.com/10.1002/lary.27839
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http://dx.doi.org/10.1002/lary.27839DOI Listing
February 2019
1 Read

VOR adaptation training and retention in a patient with profound bilateral vestibular hypofunction.

Laryngoscope 2019 Feb 19. Epub 2019 Feb 19.

Laboratory of Vestibular NeuroAdaptation, Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, U.S.A.

A novel training method known as incremental VOR adaptation (IVA) can improve the vestibulo-ocular reflex (VOR) gain for both active and passive head rotation by coupling active head rotations with a laser-projected target that moves in the opposite direction of the head at a fraction of the head velocity. A 51-year-old male with bilateral vestibular hypofunction participated in a research protocol using a portable IVA device for 645 days. Passive VOR gains improved 179% to 600%; standing posture and gait also improved. Read More

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http://dx.doi.org/10.1002/lary.27838DOI Listing
February 2019

SCUBA Medicine for otolaryngologists: Part I. Diving into SCUBA physiology and injury prevention.

Laryngoscope 2019 Feb 18. Epub 2019 Feb 18.

Department of Surgery, Division of Otolaryngology, University of Connecticut Health, Farmington, Connecticut, U.S.A.

Objectives: Introduce pertinent self-contained underwater breathing apparatus (SCUBA) physiology and corresponding terminology. Appreciate the scope of diving and related otolaryngological injury. Illustrate pathophysiologic mechanisms for diving injuries. Read More

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http://dx.doi.org/10.1002/lary.27867DOI Listing
February 2019

Novel, anatomically appropriate balloon dilation technique of the glottis to treat posterior glottic stenosis in a 3D-printed model.

Laryngoscope 2019 Feb 18. Epub 2019 Feb 18.

Department of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania, U.S.A.

Objective: Posterior glottic stenosis (PGS) often requires a destructive surgical treatment. Early PGS treatment involves glottic dilation to reduce airway constriction associated with chronic PGS. Round laryngeal dilation may not optimize posterior glottic dilation due to the teardrop shape of the glottis and may injure vocal fold tissue. Read More

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http://dx.doi.org/10.1002/lary.27524DOI Listing
February 2019

SCUBA Medicine for Otolaryngologists: Part II. Diagnostic, Treatment, and Dive Fitness Recommendations.

Laryngoscope 2019 Feb 18. Epub 2019 Feb 18.

Department of Surgery, Division of Otolaryngology, University of Connecticut Health, Farmington, Connecticut, U.S.A.

Objectives: Challenge current practices and misconceptions in treating recreational SCUBA (Self-contained underwater breathing apparatus) divers. Differentiate patients who are fit to dive and those with relative and absolute contraindications. Redefine the standard of care for fitness to dive parameters based on the most up-to-date evidence. Read More

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http://dx.doi.org/10.1002/lary.27874DOI Listing
February 2019

The role of pepsin in epithelia-mesenchymal transition in idiopathic subglottic stenosis.

Laryngoscope 2019 Feb 18. Epub 2019 Feb 18.

Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin, U.S.A.

Objectives: Idiopathic subglottic stenosis (iSGS) is commonly characterized by laryngeal fibrosis thought to arise by epithelia-mesenchymal transition (EMT) induced by chronic inflammation. Pepsin is a potent inducer of inflammation in the airways during chronic laryngopharyngeal reflux and has been observed in the subglottic mucosa of patients with iSGS, absent in normal mucosa. The aim of this study was to examine the effect of pepsin on mechanisms of EMT in laryngeal cells with implications for iSGS. Read More

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http://dx.doi.org/10.1002/lary.27879DOI Listing
February 2019

Regarding clinical implications of magnetic resonance imaging in temporomandibular disorder patients presenting ear fullness.

Laryngoscope 2019 Feb 15. Epub 2019 Feb 15.

Department of Otolaryngology-Head and Neck Surgery, University of California, Irvine, California, U.S.A.

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http://dx.doi.org/10.1002/lary.27733DOI Listing
February 2019

In reference to management and follow-up results of salivary fistulas treated with botulinum toxin.

Laryngoscope 2019 Feb 15. Epub 2019 Feb 15.

Department of Neurosciences, Otolaryngology Section, University of Padova, Padova, Italy.

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http://dx.doi.org/10.1002/lary.27682DOI Listing
February 2019

Surgery versus radiation for T1 glottic carcinoma: Second primary considerations.

Laryngoscope 2019 Feb 15. Epub 2019 Feb 15.

Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts, U.S.A.

Although early glottic carcinoma is managed with radiation therapy (RT) or surgery, there is limited data on differences in second primary cancers of the larynx. We utilized the Surveillance, Epidemiology, and End Results (SEER) database to query T1 glottic carcinomas and assess the incidence of second primary laryngeal malignancies. Cumulative hazard for second primary laryngeal malignancies was compared with the log-rank method. Read More

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http://dx.doi.org/10.1002/lary.27854DOI Listing
February 2019

In response to the letter to the editor regarding management and follow-up results of salivary fistulas treated with botulinum toxin.

Laryngoscope 2019 Feb 15. Epub 2019 Feb 15.

Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Bonn, Bonn, Federal Republic of Germany.

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http://dx.doi.org/10.1002/lary.27681DOI Listing
February 2019

In response to letter to the editor regarding: "Patient-reported versus physiologic swallowing outcomes in patients with head and neck cancer after chemoradiation".

Laryngoscope 2019 Feb 13. Epub 2019 Feb 13.

Department of Speech, Language, and Swallowing Disorders, Massachusetts General Hospital, Boston, Massachusetts, U.S.A.

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http://dx.doi.org/10.1002/lary.27857DOI Listing
February 2019

Regarding "patient-reported versus physiologic swallowing outcomes in patients with head and neck cancer after chemoradiation".

Laryngoscope 2019 Feb 13. Epub 2019 Feb 13.

Department of Radiation Oncology, University of North Carolina, Chapel Hill, North Carolina, U.S.A.

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http://doi.wiley.com/10.1002/lary.27862
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http://dx.doi.org/10.1002/lary.27862DOI Listing
February 2019
1 Read

The impact of cricothyroid involvement on adductor recovery in unilateral vocal fold paralysis.

Laryngoscope 2019 Feb 13. Epub 2019 Feb 13.

Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.

Objectives/hypothesis: Wide variation in postinjury functional recovery is a hallmark of unilateral vocal fold paralysis (UVFP), ranging from zero to full recovery. The present study examined the impact of cricothyroid (CT) muscle involvement on recovery using quantitative laryngeal electromyography (LEMG) of the thyroarytenoid-lateral cricoarytenoid (TA-LCA) muscle complex at multiple times postinjury.

Study Design: Prospective cohort study in a medical center. Read More

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http://dx.doi.org/10.1002/lary.27868DOI Listing
February 2019

Validating peritonsillar abscess drainage rates using the Pediatric hospital information system data.

Laryngoscope 2019 Feb 13. Epub 2019 Feb 13.

Department of Otolaryngology-Pediatric Otolaryngology Division, UT Southwestern Medical Center and Children's Medical Center Dallas, Dallas, Texas, U.S.A.

Objectives: To evaluate the accuracy of the Children's Hospital Association's Pediatric Health Information System (PHIS) registry data in determining surgical drainage rates as compared to a chart review on the same cohort of children with diagnosis of peritonsillar abscess.

Study Design: Retrospective analysis.

Methods: Our analysis included 200 children, ages 2 to 17 years, treated for a peritonsillar abscess from 2011 to 2016. Read More

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http://dx.doi.org/10.1002/lary.27836DOI Listing
February 2019

Selective reinnervation using phrenic nerve and hypoglossal nerve for bilateral vocal fold paralysis.

Laryngoscope 2019 Feb 12. Epub 2019 Feb 12.

Department of Otolaryngology-Head and Neck Surgery, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of China.

Objective: To evaluate the extent of airway improvement and voice quality in patients with bilateral vocal fold paralysis (BVFP) who underwent selective laryngeal reinnervation surgery.

Methods: Seven patients with BVFP caused by thyroid surgeries were enrolled. They underwent selective laryngeal reinnervation surgery. Read More

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http://dx.doi.org/10.1002/lary.27768DOI Listing
February 2019

Safety of office-based percutaneous injection laryngoplasty with calcium hydroxylapatite.

Laryngoscope 2019 Feb 12. Epub 2019 Feb 12.

Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea.

Objective: To evaluate the safety of office-based calcium hydroxylapatite (CaHA) injection laryngoplasty via the cricothyroid approach through an analysis of all procedures performed over a period of 10 years at a single institution.

Methods: In total, 962 office-based CaHA injection laryngoplasty via the cricothyroid approach procedures were performed by a single physician at our institution between 2007 and 2016. From these, 955 procedures performed in 617 patients were included in our analysis. Read More

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http://dx.doi.org/10.1002/lary.27861DOI Listing
February 2019

Outcomes of carotid-sparing IMRT for T1 glottic cancer: Comparison with conventional radiation.

Laryngoscope 2019 Feb 12. Epub 2019 Feb 12.

Multidisciplinary Larynx Cancer Working Group from the Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, U.S.A.

Objectives: We aim to report oncologic outcomes after conventional radiotherapy (ConRT) using opposed lateral beams and intensity-modulated radiation therapy (IMRT) for tumor (T)1 nodal (N)0 T1 N0 glottic squamous cell carcinoma.

Study Design: Retrospective case-control study.

Methods: We retrospectively reviewed demographic, disease, and treatment characteristics for patients treated at our institution during 2000 to 2013. Read More

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http://dx.doi.org/10.1002/lary.27873DOI Listing
February 2019

In reference to pH-neutralizing esophageal irrigations as a novel mitigation strategy for button battery injury.

Laryngoscope 2019 Feb 11. Epub 2019 Feb 11.

Division of Pediatric Otolaryngology-Head and Neck Surgery, British Columbia Children's Hospital, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1002/lary.27755DOI Listing
February 2019

Factors of success of low-dose macrolides in chronic sinusitis: Systematic review and meta-analysis.

Laryngoscope 2019 Feb 11. Epub 2019 Feb 11.

Department of Otolaryngology, Bangkok, Thailand.

Objective: To assess the prognostic factors that predict favorable outcomes of low-dose macrolides (LDMs) in treating chronic rhinosinusitis (CRS).

Methods: Randomized controlled trials studying the effects of LDMs in treating CRS were included. Data were pooled for meta-analysis. Read More

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http://dx.doi.org/10.1002/lary.27865DOI Listing
February 2019
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In Response to pH-Neutralizing Esophageal Irrigations as a Novel Mitigation Strategy.

Laryngoscope 2019 Feb 11. Epub 2019 Feb 11.

Division of Otolaryngology, Department of Surgery, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/lary.27754DOI Listing
February 2019

Histoanatomical structures of laryngeal atresia: Functional considerations.

Laryngoscope 2019 Feb 8. Epub 2019 Feb 8.

Department of Anatomy and Pathology-CHU Lille, Lille, France.

Objective: To study the histoanatomical structure of laryngeal atresia with a focus on the laryngeal functional components in order to evaluate the functional prognosis of laryngeal atresia repair.

Methods: Twenty-one consecutives cases of laryngeal atresia were diagnosed at our institution between 2009 and 2016. Morphological analysis by macroscopic exam during autopsy was performed in 19 cases. Read More

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http://dx.doi.org/10.1002/lary.27855DOI Listing
February 2019

In-Office Injection Pharyngoplasty for Velopharyngeal Insufficiency After Oropharyngeal Cancer Treatment.

Laryngoscope 2019 Feb 7. Epub 2019 Feb 7.

The Rick and Tina Caruso Department of Otolaryngology, Head and Neck Surgery, University of Southern California, Keck School of Medicine, Los Angeles, California, U.S.A.

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http://dx.doi.org/10.1002/lary.27853DOI Listing
February 2019

Innovative insertion of the palmaris major tendon after lower lip reconstruction.

Laryngoscope 2019 Feb 6. Epub 2019 Feb 6.

Department of Otolaryngology-Head and Neck Surgery and Surgical Oncology, Sunnybrook Odette Cancer Centre, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/lary.27825DOI Listing
February 2019

Regarding epistaxis in the setting of antithrombotic therapy: A comparison between factor Xa inhibitors, warfarin, and antiplatelet agents.

Laryngoscope 2019 Feb 6. Epub 2019 Feb 6.

New York University School of Medicine, Ronald O. Perelman Department of Emergency Medicine, Division of Medical Toxicology, New York, New York, U.S.A.

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http://dx.doi.org/10.1002/lary.27824DOI Listing
February 2019

In response to Epistaxis in the setting of antithrombotic therapy: A comparison between factor Xa inhibitors, warfarin, and antiplatelet agents.

Authors:
Eran Glikson

Laryngoscope 2019 Feb 6. Epub 2019 Feb 6.

Department of Otolaryngology-Head and Neck Surgery, Sheba Medical Center, Tel-Hashomer, Israel.

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http://dx.doi.org/10.1002/lary.27817DOI Listing
February 2019

Can anatomical assessment of hypopharyngolarynx in awake patients predict obstructive sleep apnea?

Laryngoscope 2019 Feb 5. Epub 2019 Feb 5.

Department of Ear, Nose, and Throat-Head and Neck Surgery, University Hospital of Nancy, Hospitals of Brabois, Vandoeuvre-lès-Nancy, France.

Objectives/hypothesis: To assess the relationships between laryngeal and hypopharyngeal morphology and obstructive sleep apnea-hypopnea syndrome (OSAHS) in awake patients.

Study Design: Prospective study.

Methods: Awake flexible fiberoptic laryngoscopy and sleep studies were performed in 80 patients for snoring or OSAHS suspicion. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/lary.27851
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http://dx.doi.org/10.1002/lary.27851DOI Listing
February 2019
5 Reads

Cost burden and resource utilization in patients with chronic rhinosinusitis and nasal polyps.

Laryngoscope 2019 Feb 5. Epub 2019 Feb 5.

Sanofi, Chilly-Mazarin, France.

Objectives/hypothesis: Establish treatment patterns and economic burden in US patients with chronic rhinosinusitis with nasal polyposis (CRSwNP) versus without chronic rhinosinusitis (CRS). Determine comparative costs of subgroups with high clinical burden.

Study Design: Observational, retrospective, case-control study. Read More

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http://dx.doi.org/10.1002/lary.27852DOI Listing
February 2019
2 Reads

Cost and efficiency of myringotomy procedures in minor procedure rooms compared to operating rooms.

Laryngoscope 2019 Feb 5. Epub 2019 Feb 5.

Department of Otolaryngology-Head and Neck Surgery, London Health Sciences Center, Western University, London, Ontario, Canada.

Objectives: Minor pediatric surgeries performed in the minor procedure room (MPR) may be more time efficient and less costly compared to those performed in the operating room (OR).

Study Design: Retrospective review.

Methods: This was a retrospective study on cost and efficiency differences of bilateral myringotomy with tube insertions performed in the MPR versus the OR. Read More

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http://dx.doi.org/10.1002/lary.27840DOI Listing
February 2019

Pressure induced tissue resection in the larynx: A preliminary canine study.

Laryngoscope 2019 Feb 4. Epub 2019 Feb 4.

Department of Otolaryngology-Head and Neck Surgery, New York University School of Medicine, New York, New York, U.S.A.

Objectives: The application of laser (light amplification by stimulated emission of radiation) energy in the larynx relies on thermal injury. The impact of this injury on adjacent tissue can be undesirable. Attempts have been made to limit the extent and range of injury to adjacent tissue. Read More

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http://dx.doi.org/10.1002/lary.27822DOI Listing
February 2019

Long-term quality of life after definitive treatment of sinonasal and nasopharyngeal malignancies.

Laryngoscope 2019 Feb 1. Epub 2019 Feb 1.

Department of Head and Neck Surgery, the University of Texas MD Anderson Cancer Center, Houston.

Objective: To evaluate long-term global and site-specific health-related quality of life (HRQoL) in patients treated for sinonasal and nasopharyngeal malignancies.

Study Design: Cross-sectional.

Methods: One hundred fourteen patients with sinonasal and nasopharyngeal malignancies received surgery, radiation, systemic chemotherapy, or a combination thereof, with curative intent. Read More

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http://dx.doi.org/10.1002/lary.27849DOI Listing
February 2019
1 Read

A contemporary review of machine learning in otolaryngology-head and neck surgery.

Laryngoscope 2019 Feb 1. Epub 2019 Feb 1.

Department of Mechanical and Industrial Engineering, University of Toronto, Toronto, Ontario, Canada.

One of the key challenges with big data is leveraging the complex network of information to yield useful clinical insights. The confluence of massive amounts of health data and a desire to make inferences and insights on these data has produced a substantial amount of interest in machine-learning analytic methods. There has been a drastic increase in the otolaryngology literature volume describing novel applications of machine learning within the past 5 years. Read More

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http://doi.wiley.com/10.1002/lary.27850
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http://dx.doi.org/10.1002/lary.27850DOI Listing
February 2019
3 Reads

Survival impact of treatment-related time intervals in nasopharyngeal carcinoma in the United States.

Laryngoscope 2019 Jan 31. Epub 2019 Jan 31.

Department of Otolaryngology-Head and Neck Surgery, Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, U.S.A.

Objective: To determine if delayed or prolonged treatment-related time intervals (TRTIs) was associated with survival in patients with nasopharyngeal carcinoma (NPC) undergoing curative-intent concurrent chemoradiation (CCRT). The TRTIs investigated were duration of radiation treatment (RTd), time to radiation start (TTR), and time to chemotherapy start (TTC).

Methods: Observational cohort study using the National Cancer Database (NCDB). Read More

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http://dx.doi.org/10.1002/lary.27818DOI Listing
January 2019

The evidence-based preoperative assessment for the otolaryngologist.

Laryngoscope 2019 Jan 31. Epub 2019 Jan 31.

Department of Otolaryngology-Head and Neck Surgery, University of South Florida, Tampa, Florida, U.S.A.

There is a narrow window of opportunity between surgical scheduling and the operative date to optimize patients for an elective surgical procedure. Traditionally, preoperative care has involved extended routine testing batteries with intermittent referrals for medical clearance. These traditions are costly, inefficient, and yield no clear reduction in perioperative morbidity and mortality. Read More

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http://dx.doi.org/10.1002/lary.27845DOI Listing
January 2019
1 Read

Clinical applications of three-dimensional printing in otolaryngology-head and neck surgery: A systematic review.

Laryngoscope 2019 Jan 30. Epub 2019 Jan 30.

Department of Otolaryngology-Head and Neck Surgery, University of Toronto, Toronto, Ontario, Canada.

Objectives: Medical three-dimensional (3D) printing, the fabrication of handheld models from medical images, has the potential to become an integral part of otolaryngology-head and neck surgery (Oto-HNS) with broad impact across its subspecialties. We review the basic principles of this technology and provide a comprehensive summary of reported clinical applications in the field.

Methods: Standard bibliographic databases (MEDLINE, Embase, Cumulative Index to Nursing and Allied Health Literature, Web of Science, and The Cochrane Central Registry for Randomized Trials) were searched from their inception to May 2018 for the terms: "3D printing," "three-dimensional printing," "rapid prototyping," "additive manufacturing," "computer-aided design," "bioprinting," and "biofabrication" in various combinations with the terms: "ptolaryngology," "head and neck surgery," and "otology. Read More

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http://doi.wiley.com/10.1002/lary.27831
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http://dx.doi.org/10.1002/lary.27831DOI Listing
January 2019
3 Reads
2.032 Impact Factor

Neuroprotective factors and incident hearing impairment in the epidemiology of hearing loss study.

Laryngoscope 2019 Jan 30. Epub 2019 Jan 30.

Department of Ophthalmology and Visual Sciences, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin.

Objective: Hearing impairment (HI) is common in aging adults. Aldosterone, insulin-like growth factor (IGF1), and brain-derived neurotrophic factor (BDNF) have been identified as potentially protective of hearing. The present study aims to investigate these relationships. Read More

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http://dx.doi.org/10.1002/lary.27847DOI Listing
January 2019

Feasibility and tolerability of measuring translaryngeal pressure during exercise.

Laryngoscope 2019 Jan 30. Epub 2019 Jan 30.

Pediatric Department, Haukeland University Hospital, Bergen, Norway.

Objectives/hypothesis: To determine if simultaneous tracheal and supraglottic pressure measurement performed during a continuous laryngoscopy exercise (CLE) test is possible, tolerable, and feasible, and if so, whether measurements can be used to determined airflow resistance over the larynx, thus providing an objective outcome measure for the CLE test, the gold standard for diagnosing exercise-induced laryngeal obstruction.

Study Design: Explorative descriptive clinical study.

Methods: A CLE test was performed with the addition of two pressure sensors (Mikro-Cath 825-0101; Millar, Houston, TX) placed at the epiglottic tip and at the fifth tracheal ring. Read More

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http://dx.doi.org/10.1002/lary.27846DOI Listing
January 2019
3 Reads
2.032 Impact Factor

The benefit of trans-attic endoscopic control of ossicular prosthesis after cholesteatoma surgery.

Laryngoscope 2019 Jan 30. Epub 2019 Jan 30.

ENT Department, Hamad Medical Corporation, Doha, Qatar.

Objective: To show the efficiency of using transmastoid atticotomy (TMA) endoscopy on the outcome of ossiculoplasty in patients with cholesteatoma. TMA is often performed as part of the surgical management of patients with middle ear cholesteatoma extending to the epitympanum. TMA can also be used as an access for endoscopic view to confirm the right alignment and stability of the ossicular prosthesis because the reconstruction of the tympanic membrane will obscure the visualization of the prosthesis. Read More

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http://doi.wiley.com/10.1002/lary.27848
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http://dx.doi.org/10.1002/lary.27848DOI Listing
January 2019
5 Reads
2.032 Impact Factor

Impact of treating facilities' type and volume in patients with major salivary gland cancer.

Laryngoscope 2019 Jan 30. Epub 2019 Jan 30.

Department of Otolaryngology-Head and Neck Surgery, University of Missouri School of Medicine, Columbia, Missouri, U.S.A.

Objectives/hypothesis: Investigate the relationship between facility volume and type on overall survival (OS) in patients with major salivary gland cancer undergoing surgical treatment.

Study Design: Retrospective review of the National Cancer Database (NCDB) 2004-2015.

Methods: The NCDB was queried for patients with surgically treated major salivary gland cancer. Read More

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http://dx.doi.org/10.1002/lary.27844DOI Listing
January 2019

Engineering of scaffold-free tri-layered auricular tissues for external ear reconstruction.

Laryngoscope 2019 Jan 30. Epub 2019 Jan 30.

Department of Chemical Engineering, Ryerson University, Toronto, Ontario, Canada.

Objectives: Current strategies for external ear reconstruction can lead to donor site morbidity and/or surgical complications. Tissue-engineered auricular tissues may provide readily available reconstructive materials that resemble native auricular tissue, which is composed of a cartilaginous region sandwiched between two perichondrial layers. We previously developed scaffold-free bi-layered auricular tissues, consisting of a perichondrial layer and a cartilaginous layer, by cultivating chondrocytes and perichondrial cells in a continuous flow bioreactor. Read More

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http://dx.doi.org/10.1002/lary.27823DOI Listing
January 2019

Patient-defined duration of benefit from juvederm (hyaluronic acid) used in injection laryngoplasty.

Laryngoscope 2019 Jan 30. Epub 2019 Jan 30.

Department of Otolaryngology-Head and Neck Surgery, Washington University in St. Louis School of Medicine, St. Louis, Missouri, U.S.A.

Objectives/hypothesis: Injection laryngoplasty has become valuable in treating laryngologic disorders including vocal cord atrophy, paralysis, and paresis. Although materials such as carboxymethylcellulose and calcium hydroxylapatite are Food and Drug Administration (FDA) approved, they are not without limitations. Juvederm (hyaluronic acid) is an alternative treatment that is not FDA approved. Read More

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http://dx.doi.org/10.1002/lary.27842DOI Listing
January 2019

Eye movement desensitization and reprocessing as a treatment for tinnitus.

Laryngoscope 2019 Jan 28. Epub 2019 Jan 28.

Norfolk and Norwich University Hospital National Health Service Foundation Trust, Norwich, United Kingdom.

Objectives/hypothesis: To determine the effectiveness of eye movement desensitization and reprocessing (EMDR) as a treatment for tinnitus.

Study Design: Single-site prospective interventional clinical trial at a university hospital in the United Kingdom.

Methods: Participants were provided with tEMDR. Read More

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http://doi.wiley.com/10.1002/lary.27841
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http://dx.doi.org/10.1002/lary.27841DOI Listing
January 2019
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Qualitative and quantitative scintigraphy in sialorrhea before and after botulinum toxin injection.

Laryngoscope 2019 Jan 28. Epub 2019 Jan 28.

Instituto de Ciências Biomédicas, Laboratório de Motilidade Digestiva e Imagem, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.

Objectives/hypothesis: Sialorrhea is excessive saliva production and its usual escape of from the oral cavity. The use of botulinum toxin has been preconized, but its effectiveness until now has been unreliably measured. Our objective was to qualitatively and quantitatively determine the effectiveness of botulinum toxin injection in the reduction of saliva production by the parotid gland. Read More

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http://dx.doi.org/10.1002/lary.27826DOI Listing
January 2019

Positive airway pressure ventilation and complications in pediatric tracheocutaneous fistula repair.

Laryngoscope 2019 Jan 28. Epub 2019 Jan 28.

Department of Otolaryngology-Head and Neck Surgery, University of Michigan Hospitals and Health Centers, Ann Arbor, Michigan, U.S.A.

Objectives: Surgical repair of persistent tracheocutaneous fistula in children may be complicated by tracheal air leak with resultant subcutaneous emphysema, pneumomediastinum, and/or pneumothorax. We first sought to identify clinical risk factors for postoperative complications after primary repair of persistent tracheocutaneous fistula in children. Second, the type and frequency of complications in patients administered positive airway pressure ventilation (e. Read More

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http://dx.doi.org/10.1002/lary.27834DOI Listing
January 2019
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Comparison of balance outcomes according to treatment modality of vestibular schwannoma.

Laryngoscope 2019 Jan 28. Epub 2019 Jan 28.

Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, South Korea.

Objectives: We sought to compare balance outcomes according to treatment modality of vestibular schwannoma (VS) via a meta-analysis that divided measuring tools of balance outcomes into three categories based on type.

Methods: A comprehensive review of the literature from January 1966 to September 2017 was performed, looking for studies about long-term balance outcomes after microsurgery (MS), radiotherapy (RT), or observation for VS. A comprehensive meta-analysis was used to analyze effect sizes, explore possible causes of heterogeneity, and check publication bias with a funnel plot and Egger's regression. Read More

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http://dx.doi.org/10.1002/lary.27830DOI Listing
January 2019