92,989 results match your criteria Laryngeal Carcinoma Imaging


[Endoscopic keel placementto treat and prevent-bilateral vocal cord adhension].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(23):1821-1825

Department of Otorhinolaryngology Head and Neck Surgery, Eye Ear Nose Throat Hospital of Fudan University, Shanghai, 200031, China.

To investigate the effectiveness of endoscopic keel placement for the prevention and treatment of bilateral vocal cord adhesion. There are 47 cases with bilateral vocal cord lesions and 38 cases with laryngeal adhesion in this study. Bilateral vocal cord lesions were removed and laryngeal adhesion was cut and divided. Read More

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December 2018
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[Effect of serum HGF and CK18 in patients with laryngeal cancer on postoperative prognosis].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(23):1791-1794

Department of Otorhinolaryngology, the First People's Hospital of Xianyang, Xianyang, 712000, China.

To investigate the correlation between the levels of serum cytokeratin 18 (CK18) and hepatocyte growth factor (HGF) and tumor stage and prognosis in patients with laryngeal carcinoma. Patients with laryngeal cancer who were admitted to our hospital from January 2012 to December 2013 were enrolled. Blood samples were collected for CK18 and HGF detection, and postoperative prognosis data were collected at regular follow-up. Read More

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December 2018
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[Two cases of piriform pit carcinoma were repaired with thyroid lobe].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Oct;32(19):1511-1514

Two cases with piriform fossa cancer underwent larynx lateral wall repair surgery. Case 1: The patient was admitted to the hospital because of pharyngeal discomfort with swallowing pain for 2 months Electronic laryngoscopy revealed neoplasm in the left piriform fossa. Space occupying lesion in left piriform fossa and paranasal space was found in MRI scan. Read More

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October 2018
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[Application progress of CO₂ in the treatment of laryngology diseases].

Authors:
W B Lei Y Xu J Deng Y Li

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Oct;32(19):1447-1450

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October 2018
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[Analysis of infants with moderate to severe laryngomalacia].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Sep;32(18):1406-1409

Department of Otolaryngology Head and Neck Surgery, the First Affiliated Hospital of Xiamen University, Xiamen, 361003, China.

To investigate the clinical features and the treatment of moderate-severe laryngeallacia, and the application of CO₂laser supraglotation in laryngeallacia.Collecting the clinical data of 18 infants with moderate-to-severe laryngeallacia diagnosed in our hospital,10 cases were moderate. Eight cases were severe children; according to the classification of laryngeallacia, most of them were mixed type, including 2 cases of type Ⅱ, 3 cases of type Ⅲ, 5 cases of typeⅠ + type Ⅱ, 7 cases of typeⅡ+ type Ⅲ, and 1 case of typeⅠ+ typeⅡ + type Ⅲ. Read More

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September 2018

[Features of cognitive function in patients with laryngeal carcinoma].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Sep;32(18):1396-1399

Department of Otolaryngology Head and Neck Surgery, the First Hospital, Shanxi Medical University; Shanxi Key Laboratory of Otorhinolaryngology Head and Neck Cancer.

To study the differences in cognitive function between patients with laryngeal carcinoma and healthy volunteers. Patients with laryngeal carcinoma who have been first diagnosed with laryngeal carcinoma, but not received treatment at the Department of Otolaryngology in two hospitals in Shanxi Province and healthy volunteers of the same age, gender-matched and similar education were studied for the purpose to evaluate the cognitive status by using the Wechsler memory scale.No significant difference of age, gender and educational level was found between both groups(>0. Read More

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September 2018

[Preliminary experience of transoral robotic surgery in laryngeal and hypopharyngeal tumors with da Vinci surgical system].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Jul;32(14):1065-1070

Department of Otolaryngology Head and Neck Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.

The purpose of this study was to summarize preliminary clinical experience of transoral robotic surgery (TORS) in laryngeal and hypopharyngeal tumors with da Vinci surgical system.Twelve patients were reviewed who were diagnosed with laryngeal (=7) and hypopharyngeal tumors (=5) and treated with TORS in Beijing Anzhen Hospital from July 1, 2016 to January 31, 2018.Ten cases were male and two cases were female. Read More

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[Application of da Vinci robot's bilateral axillo-breast approach in thyroid surgery of obese patients].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Jul;32(14):1061-1065

Departmeng of Thyroid and Breast Surgery, Jinan Military General Hospital, Jinan, 250031, China.

To discuss the effect of obesity on the operation of thyroid gland surgery and surgical results.The clinical data of 446 patients who underwent robot thyroid surgery through bilateral axillo-breast approach (BABA) from the General Hospital of Jinan Military region from February 2014 to November 2017 were analyzed retrospectively, and the patients were divided into BMI<25 kg/m²; group, BMI 25-30 kg/m²; group and BMI>30 kg/m²; group according to body mass index (BMI). The operative complications were compared between the three groups of benign and malignant patients, such as operation time, postoperative lead flow, postoperative hospitalization time, tumor size (malignant), lymph node metastasis (malignant), cosmetic satisfaction score, laryngeal nerve injury and parathyroid function decrease. Read More

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[Robotic head and neck surgery at the Chinese University of Hong Kong].

Authors:
Y K Chan W Y Wong

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Jul;32(14):1056-1060

Department of Otorhinolaryngology, Head and Neck Surgery,The Chinese University of Hong Kong.

Robotic surgery in the head and neck region has been used to approach many different areas within the head and neck region. Here we describe our experiences of its application at The Chinese University of Hong Kong.This is a retrospective review of all cases operated by the two authors since Jan 2015 at the Department of Otorhinolaryngology, Head and Neck Surgery, The Chinese University of Hong Kong. Read More

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[Robot-assisted transaxillary thyroidectomy: our early experience].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Jul;32(14):1051-1055

Department of Otolaryngology, Sun Yat-sen Memorial Hospital,Sun Yat-sen University, Guangzhou, 510120, China.

To evaluate the feasibility, effectiveness and safety of robot-assisted transaxillary thyroidectomy (RATT). The clinical data of 66 patients undergoing RATT from November 2016 to May 2018 were prospectively collected and analyzed. The average age was (38. Read More

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July 2018
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[Advances in prevention of pharyngocutaneous fistula after total laryngectomy].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(24):1917-1922

Total laryngectomy is a common method for the treatment of malignant tumors of the pharynx and larynx in China, but pharyngocutaneous fistula often happens after surgery, which burdens patients and affects postoperative recovery. At present, there are many measures to prevent pharyngocutaneous fistula, including strengthening nutrition pre-operative and post-operative, testing related indicators, controlling comorbidities, rational use of drugs, regular oral care, optimal selection of incision closure, and using of flaps and special materials during operation, etc. However, the choice of specific program needs to take care of the patient's condition, surgeon's skills and hospital conditions, and often requires multiple programs to be used together throughout the perioperative period. Read More

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December 2018

[Two cases report of laryngeal malignant melanoma and a review of literatures].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(24):1906-1909

Two patients both complained of one year history of hoarseness and the clinical manifestations and imageology among 2 patients were lack of specificity. The pathological tissue was successfully eradicated by surgical removal. Histopathology established laryngeal malignant melanoma as the diagnosis. Read More

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December 2018
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Compatibility of CO laser surgery and fluorescence detection in head and neck cancer cells.

Head Neck 2018 Dec 14. Epub 2018 Dec 14.

Department of Otorhinolaryngology and Head and Neck Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.

Background: Surgical treatment of cancer requires tumor excision with emphasis on function preservation which is achieved in (early stage) laryngeal cancer by transoral carbon dioxide (CO ) laser surgery. Whereas conventional laser surgery is restricted by the surgeon's visual recognition of tumor tissue, new approaches based on fluorescence-guided surgery (FGS) improve the detection of the tumor and its margin. However, it is unclear whether fluorophores are compatible with high-power laser application or whether precision is compromised by laser-induced bleaching of the dye. Read More

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December 2018
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AHNS series: Do you know our guidelines? Review of current knowledge on laryngeal cancer.

Authors:
Burak Karabulut

Head Neck 2018 Dec 14. Epub 2018 Dec 14.

Department of Otolaryngology, University of Health Sciences Umraniye Education and Research Hospital, Istanbul, Turkey.

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December 2018
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Serum matrix metalloproteinase 8 and tissue inhibitor of metalloproteinase 1: Potential markers for malignant transformation of recurrent respiratory papillomatosis and for prognosis of laryngeal cancer.

Head Neck 2018 Dec 14. Epub 2018 Dec 14.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Background: Biomarkers that could predict malignant transformation of recurrent respiratory papillomatosis (RRP) would be useful in patient follow-up. We investigated whether serum matrix metalloproteinase 8 (MMP-8) and tissue inhibitor of metalloproteinase 1 (TIMP-1) could predict malignant transformation of RRP and whether they associate with survival in laryngeal squamous cell carcinoma (LSCC) without preexisting RRP.

Methods: We analyzed serum MMP-8 (S-MMP-8) and serum TIMP-1 (s-TIMP-1) in 114 patients: 55 were treated for RRP and 59 for LSCC without preexisting RRP. Read More

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December 2018

Association between comorbidity and survival in head and neck cancer: Results from Head and Neck 5000.

Head Neck 2018 Dec 14. Epub 2018 Dec 14.

National Institute of Health (NIHR) Bristol Biomedical Research Centre, Nutrition Theme, University of Bristol, Bristol, United Kingdom.

Background: People with head and neck cancer have higher comorbidity levels but it remains unclear if pretreatment comorbidity is an independent prognosticator in head and neck cancer.

Methods: Survival analyses were performed using data from participants in a UK multicentre cohort study with cancers of the oral cavity (n = 668), oropharynx (n = 1074), and larynx (n = 530). Survival analyses were incrementally adjusted for age, sex, marital status, income, education, stage, alcohol, and smoking. Read More

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December 2018

Knockdown of DGCR5 enhances the radiosensitivity of human laryngeal carcinoma cells via inducing miR-195.

J Cell Physiol 2018 Dec 13. Epub 2018 Dec 13.

Department of Oncology, RenMin Hospital of Wuhan University, Wuhan, China.

Long noncoding RNAs (lncRNAs) exert critical roles in the development of various cancers, including human laryngeal cancer. Radioresistance contributes to the predominant causes of laryngeal cancer recurrence after radiotherapy. The aim of our study was to investigate the association of dysregulated lncRNA and radiation resistance in human larynx squamous carcinoma. Read More

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December 2018

Isolated Recovery of Adductor Muscle Function Following Bilateral Recurrent Laryngeal Nerve Injuries.

Laryngoscope 2018 Dec 13. Epub 2018 Dec 13.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Szeged, Szeged, Hungary.

Objectives/hypothesis: The aim of this study was to analyze the phoniatric and respiratory outcomes of a subset of bilateral vocal cord paralysis (BVCP) patients who were all treated with unilateral endoscopic arytenoid abduction lateropexy (EAAL). EAAL is a nondestructive, minimally invasive glottis widening operation, which does not damage either the surgically treated or the contralateral vocal cord. Therefore, it does not impair the regeneration potential of the recurrent laryngeal nerve. Read More

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December 2018

Office-based transnasal esophagoscopy biopsies for histological diagnosis of head and neck patients.

Laryngoscope 2018 Dec 13. Epub 2018 Dec 13.

Department of Otolaryngology-Head and Neck Surgery, Norfolk and Norwich University Hospital, Norwich, United Kingdom.

Objectives/hypothesis: To present yield of transnasal esophagoscopy (TNE) biopsies of upper aerodigestive tract (UADT) lesions and define the role of TNE as a safe alternative to rigid endoscopy.

Study Design: Retrospective case series.

Methods: All patients who underwent TNE-guided biopsies attempted over a 2-year period were included. Read More

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December 2018

Vocal fold botulinum toxin injection for refractory paradoxical vocal fold motion disorder.

Laryngoscope 2018 Dec 13. Epub 2018 Dec 13.

Department of Otolaryngology-Head and Neck Surgery, Ohio State University Wexner Medical Center, Columbus, Ohio, U.S.A.

Objective: Demonstrate efficacy of vocal fold botulinum toxin injection for treatment of refractory paradoxical vocal fold motion disorder (PVFMD).

Methods: A retrospective review was completed of patients diagnosed with PVFMD who underwent vocal fold botulinum toxin injection for dyspnea symptoms that persisted despite laryngeal control therapy, medical management, and biofeedback therapy. Outcomes measured included overall improvement and resolution of dyspnea symptoms, number of botulinum toxin injections and dose range, change in dyspnea severity index (DSI) scores, and adverse effects of injection therapy. Read More

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December 2018

MicroRNA-384 regulates cell proliferation and apoptosis through directly targeting WISP1 in laryngeal cancer.

J Cell Biochem 2018 Dec 12. Epub 2018 Dec 12.

Department of Otolaryngology-Head and Neck Surgery, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Laryngeal cancer (LC) is an increasingly common malignant tumors of head and neck cancer. Aberrant expression of microRNA (miRNA) is closely related with LC development. In the current study, we investigated the biological function and underlying molecular mechanism of miR-384 in LC. Read More

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December 2018

Real-Time Light-Guided Vocal Fold Injection: Ex Vivo Feasibility Study in a Canine Model.

Laryngoscope 2018 Dec 12. Epub 2018 Dec 12.

Department of Otorhinolaryngology-Head and Neck Surgery and Biomedical Research Institute, Republic of Korea.

Objective: The transcricothyroid (CT) membrane approach is a good option for office-based vocal fold injection (VFI). However, because the needle tip is invisible during injection using the CT approach, precise localization requires a high level of experience, and mastering this approach involves a steep learning curve. To overcome current limitations, we conceptualized a novel technique: real-time light-guided VFI (RL-VFI), which enables simultaneous VFI under direct visualization of the lighted needle tip. Read More

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December 2018

Motor endplate-expressing cartilage-muscle implants for reconstruction of a denervated hemilarynx.

Laryngoscope 2018 Dec 12. Epub 2018 Dec 12.

Department of Speech, Language and Hearing Sciences, West Lafayette, Indiana, U.S.A.

Objective: Tissue engineering of the larynx requires a complex, multiple tissue layer design. Additionally, spontaneous reinnervation of the larynx after recurrent laryngeal nerve (RLN) injury is often disorganized, resulting in subpar function. This study investigates use of tissue-engineered cartilage and motor endplate-expressing (MEE) tissue-engineered skeletal muscle implants for laryngeal reconstruction and the promotion of organized reinnervation after RLN injury. Read More

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December 2018

Mutational profiles of persistent/recurrent laryngeal squamous cell carcinoma.

Head Neck 2018 Dec 12. Epub 2018 Dec 12.

Department of Otolaryngology - Head and Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan.

Background: We sought to describe targeted DNA sequencing data of persistent/recurrent laryngeal squamous cell carcinoma (LSCC) and to compare gene-specific alteration frequencies with that of primary, untreated LSCC specimens from The Cancer Genome Atlas (TCGA).

Methods: The tumors of 21 patients with persistent/recurrent LSCC were subjected to targeted DNA sequencing using the Ion AmpliSeq Comprehensive Cancer Panel. Gene-specific alteration frequencies were compared (Chi-Square test) to primary, untreated LSCC sequencing data from TCGA using the cBioPortal platform. Read More

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December 2018
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Long-term changes in vocal function after supracricoid partial laryngectomy with cricohyoidoepiglottopexy for laryngeal cancer.

Head Neck 2018 Dec 12. Epub 2018 Dec 12.

Department of Otolaryngology-Head and Neck Surgery, Graduate School of Medicine, Kumamoto University, Kumamoto, Japan.

Background: The purpose of this study was to assess changes in vocal function over time following supracricoid partial laryngectomy with cricohyoidoepiglottopexy (SCL-CHEP).

Methods: A total of 17 patients who underwent SCL-CHEP for laryngeal squamous cell carcinoma between 2007 and 2015 were reviewed. We examined maximum phonation time (MPT), mean airflow rate (MFR), voice intensity, the grade, roughness, breathiness, asthenia, and strain (GRBAS) scale, Voice Handicap Index-10 (VHI-10), and voice-related quality of life (V-RQOL) scores. Read More

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December 2018

A Rare Case of Laryngopyocele with Airway Obstruction.

J Clin Imaging Sci 2018 15;8:42. Epub 2018 Nov 15.

Department of Radiology, Tuen Mun Hospital, Tuen Mun, Hong Kong.

Laryngocele is a rare entity and can be defined as an abnormal cystic dilatation of saccule of the laryngeal ventricle with communication to the lumen of larynx. Laryngopyocele is a rare complication of laryngocele when it is infected. Patients may present with fever, neck swelling, shortness of breath, and hoarseness. Read More

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November 2018

A rare case of laryngeal cleft in association with VACTERL and malrotation.

Radiol Case Rep 2019 Mar 6;14(3):315-319. Epub 2018 Dec 6.

Staten Island University Hospital/Northwell, 475 Seaview Ave. Staten Island, NY 10305, USA.

We report a rare case of a neonatal girl who presented with coughing and dyspnea immediately after feeds. At birth, she was noted to have an imperforate anus with a posterior fourchette fistula from which she was stooling. Initial imaging with radiography showed a normal bowel gas pattern; however, lumbar vertebral anomalies were noted. Read More

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March 2019
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Oxidative stress induced by carboplatin promotes apoptosis and inhibits migration of HN-3 cells.

Oncol Lett 2018 Dec 10;16(6):7131-7138. Epub 2018 Oct 10.

Department of Otolaryngology-Head and Neck Surgery, Shanghai Key Clinical Disciplines of Otorhinolaryngology, Eye and ENT Hospital of Fudan University, Shanghai 200031, P.R. China.

Laryngeal squamous cell carcinoma (LSCC) is currently a serious public health problem in China; thus, it is urgent to identify effective treatment strategies for this disease. Previous studies demonstrated that reactive oxygen species (ROS) serve important roles in the apoptosis of LSCC cells. It has also been indicated that carboplatin (CBDCA), a second-generation platinum compound with broad antineoplastic properties, is able to induce oxidative stress to produce ROS, which in turn promotes apoptosis. Read More

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December 2018
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Thrombosis of the internal jugular vein in the ENT-department - Prevalence, causes and therapy: A retrospective analysis.

Auris Nasus Larynx 2018 Dec 10. Epub 2018 Dec 10.

Department of Oto-Rhino-Laryngology, Head and Neck Surgery, Ulm University Medical Center, Germany.

Objective: Less than 5% of deep vein thrombosis is due to thrombosis of the internal jugular vein. Genetic, malignant or inflammatory underlying diseases as well as insertion of venous catheters can be responsible for this pathology. Due to its rare occurrence, it is difficult to find systematic research about thrombosis of the internal jugular vein. Read More

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December 2018
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Sinonasal inverted papilloma associated with small cell neuroendocrine carcinoma: A case report and literature review of rare malignancies associated with inverted papilloma.

Auris Nasus Larynx 2018 Dec 10. Epub 2018 Dec 10.

Departments of Otorhinolaryngology, Nagoya City University, Japan.

We report a rare case of sinonasal inverted papilloma (IP) associated with small cell neuroendocrine carcinoma (SNEC). To our knowledge, this is the first report to describe SNEC found during the treatment of sinonasal IP. Surgery and five cycles of cisplatin plus etoposide with concurrent intensity modulated radiation therapy were performed. Read More

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December 2018

Resident Education in Laryngeal Stroboscopy and Perceptual Voice Evaluation: An Assessment.

J Voice 2018 Dec 10. Epub 2018 Dec 10.

Department of Otolaryngology-Head & Neck Surgery, University of Kansas School of Medicine, Kansas City, Kansas.

Objectives: To evaluate otolaryngology residents' level of confidence and understanding in interpreting laryngeal stroboscopy.

Methods: Otolaryngology residents from three residency programs with fellowship-trained laryngologists on faculty were invited to participate. An assessment consisting of a survey and five stroboscopic exams was administered. Read More

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December 2018

Detailed computational analysis of flow dynamics in an extended respiratory airway model.

Clin Biomech (Bristol, Avon) 2018 Dec 7;61:105-111. Epub 2018 Dec 7.

School of Engineering, RMIT University, PO Box 71, Bundoora, VIC 3083, Australia; Key Laboratory of Ministry of Education for Advanced Reactor Engineering and Safety, Institute of Nuclear and New Energy Technology, Tsinghua University, PO Box 1021, Beijing 100086, China. Electronic address:

Background: Understanding respiratory physiology can aid clinicians in diagnosing the cause of respiratory symptoms or shed light on drug delivery inhaler device optimisation. However, the sheer complexity of the human lung prohibits a full-scale study.

Methods: In this study, a realistic respiratory airway model including large-to-small conducting airways was built. Read More

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December 2018

Microbiome and disease in the upper airway.

Curr Opin Allergy Clin Immunol 2018 Dec 12. Epub 2018 Dec 12.

Department of Head and Neck Surgery, University of Colorado Medical Center, Denver, California, USA.

Purpose Of Review: Microbiome refers to the genetic potential of resident microorganisms that inhabit a given niche. The exact role of the microbiome and its relation to chronic disease processes remains largely unknown, although various associations have been observed. We reviewed current literature investigating the microbiome of the upper airway by subsite (nasal cavity, sinus cavities, nasopharynx, and larynx) and its relation to chronic inflammatory disease processes. Read More

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December 2018

Survival analysis of distant metastasis of laryngeal carcinoma: analysis based on SEER database.

Eur Arch Otorhinolaryngol 2018 Dec 12. Epub 2018 Dec 12.

Department of Urology, The Second Affiliated Hospital of Fujian Medical University, Licheng District Zhongshan North Road, Quanzhou, 362000, Fujian, China.

Background: The purpose of this study was to investigate the prognostic factors and the value of surgical treatment of patients with newly diagnosed laryngeal cancer with distant metastasis (DM).

Methods: The Surveillance, Epidemiology and End Result database (SEER) was used to analyze 446 patients with laryngeal cancer with DM at the time of initial diagnosis from 2010 to 2014.The survival prognosis of patients with DM was performed by using Kaplan-Meier and log-rank test. Read More

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December 2018

[Feasibility of supraglottic tracheal tube ventilation during painless fiberbronchoscopy].

Zhonghua Yi Xue Za Zhi 2018 Dec;98(46):3767-3772

Department of Anesthesiology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.

To evaluate the feasibility and safety of supraglottic tracheal tube ventilation by comparing with modified laryngeal mask airway ventilation during painless fiberbronchoscopy. This was a prospective study. Twenty-eight patients undergoing painless fiberbronchoscopy in Hangzhou First People's Hospital were randomly divided into 2 groups(=14): supraglottic tracheal tube ventilation(group A) and modified laryngeal mask airway(group B). Read More

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December 2018

Basaloid Laringyeal Carcinoma on o Patient with Pneumonectomy Due to Advanced Tuberculosis.

Curr Health Sci J 2015 Oct-Dec;41(4):401-405. Epub 2015 Dec 22.

Department of ENT, Emergency Hospital Grigore Alexandrescu, București, Romania.

The basaloid carcinoma is a rare and distinct type of squamous carcinoma. Of all the squamous carcinomas, the basaloid tumor is noted for its high aggressivity and fast replication rate. It is usually discovered within the upper levels of the larynx (supraglottis), the tongue base or the piriform sinuses in male patients ranging from sixty to eighty years old. Read More

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December 2015

Severity of Retrognathia and Glossoptosis Does Not Predict Respiratory and Feeding Disorders in Pierre Robin Sequence.

Front Pediatr 2018 20;6:351. Epub 2018 Nov 20.

Department of Pediatrics, APHP, Hôpital Universitaire Necker-Enfants Malades, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.

Pierre Robin sequence (PRS) may lead to life-threatening respiratory and feeding disorders. With the aim to analyse the association of the severities of retrognathia and glossoptosis with those of respiratory and feeding disorders, we retrospectively studied a series of 50 infants with retrognathia, glossoptosis, cleft palate, and airway obstruction. The patients were managed from birth to at least 6 years of age by a single pediatric team at the Armand Trousseau Hospital in Paris within a 12 years period (2000-2012). Read More

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November 2018

Efficacy of laser surgery versus radiotherapy for treatment of glottic carcinoma: a systematic review and meta-analysis.

Lasers Med Sci 2018 Dec 6. Epub 2018 Dec 6.

Nursing College of Shanxi Medical University, Taiyuan, 030001, Shanxi, People's Republic of China.

Laser surgery and radiotherapy are the two most common ways to treat glottic carcinomas, which is more efficacious and remains controversial. PubMed, Embase, and Cochrane Library were searched to identify relevant studies of laser surgery versus radiotherapy in patients with glottic carcinomas through April 2017. Sensitivity analysis and subgroup analysis were performed to evaluate heterogeneity. Read More

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December 2018

Nonintubated laryngomicrosurgery with Transnasal Humidified Rapid-Insufflation Ventilatory Exchange: A case series.

J Formos Med Assoc 2018 Dec 3. Epub 2018 Dec 3.

Department of Anesthesiology, National Taiwan University, College of Medicine and Hospital, No. 7, Chung-Shan S. Rd., Taipei, Taiwan. Electronic address:

Background: Nonintubation anaesthesia for laryngomicrosurgery (LMS) provides both excellent visualization of the surgical field and complete examination on vocal cord. However, adequate oxygenation remains challenging during nonintubated LMS. Recently, transnasal humidified rapid-insufflation ventilator exchange (THRIVE) has been reported effectively maintaining apneic oxygenation in patient with difficult airways. Read More

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December 2018

The risks of cancer development in systemic lupus erythematosus (SLE) patients: a systematic review and meta-analysis.

Arthritis Res Ther 2018 Dec 6;20(1):270. Epub 2018 Dec 6.

Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, No. 300 Guangzhou Road, Nanjing, 210029, China.

Background: Although accumulating data have suggested the development of cancer in systemic lupus erythematosus (SLE) patients, these results remain inconsistent. To examine such a putative association, this analysis reports the association between SLE and the risks of 24 cancer types.

Methods: Online databases PubMed, EMBASE, and Web of Science were searched comprehensively for eligible studies, published up to 15 May 2018. Read More

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December 2018

[Investigation of the diagnostic value of anti-dense fine speckled 70/lens epithelium derived growth factor p75 autoantibody for autoimmune diseases].

Mikrobiyol Bul 2018 Oct;52(4):413-424

Ankara Training and Research Hospital, Clinic of Medical Microbiology, Ankara, Turkey.

Antinuclear antibodies (ANA) are the autoantibodies that are produced against nuclear antigens in the cell nucleus and/or cytoplasm, and are one of the important diagnostic criteria in systemic autoimmune rheumatic diseases (SARD). Until today, several methods have been developed for detecting ANA's. However, indirect immunofluorescence (IIF) technique, that is also known as one of the oldest methods, is still the most commonly used one. Read More

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October 2018

Laryngeal hereditary hemorrhagic telangiectasia.

Ear Nose Throat J 2018 Dec;97(12):388

Laboratory of Phonetics, Faculty of Psychology, Research Institute for Language Sciences and Technology, University of Mons, Mons, Belgium.

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December 2018

Assessment of the Safety of the New Hybrid Pencil Type Energy (NP) Device Used Close to the Recurrent Laryngeal Nerve in a Porcine Model: Comparison With a Conventional Electrosurgical Knife.

Surg Innov 2018 Dec 12:1553350618817646. Epub 2018 Dec 12.

1 Keio University, School of Medicine Tokyo, Japan.

Background: Recurrent laryngeal nerve (RLN) paralysis is mainly associated with esophagectomy, and it may result in not only other morbidities, such as aspiration pneumonia, but also in long-term issues. Therefore, an approach to prevent RLN paralysis is necessary. The present study was designed to determine the technical usability of the new hybrid pencil type energy (NP) device developed by Olympus Corporation (Tokyo, Japan) and compare it with a conventional electrosurgical knife (EK) for resection around the RLN lymph nodes. Read More

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December 2018

Detection of Autoantibodies by Indirect Immunofluorescence Cytochemistry on Hep-2 Cells.

Methods Mol Biol 2019 ;1901:19-46

Rheumatology Division, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.

Indirect immunofluorescence assay (IFA) has been used for detection of autoantibodies against cellular antigens for more than 50 years. Originally using rodent tissue as substrate, the method was optimized by using the human immortal HEp-2 cell line derived from a larynx epidermal carcinoma. The HEp-2/IFA platform allows for optimal visualization of several cellular domains recognized by autoantibodies in the samples being tested. Read More

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January 2019
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Transoral Robotic Thyroidectomy for Papillary Thyroid Carcinoma: Perioperative Outcomes of 100 Consecutive Patients.

World J Surg 2018 Dec 11. Epub 2018 Dec 11.

Department of Surgery, KUMC Thyroid Center, Korea University Hospital, Korea University College of Medicine, 73, Inchon-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea.

Background: Endoscopic transoral thyroidectomy is a recently introduced technique of remote access thyroidectomy. We previously reported the feasibility of the robotic approach (TORT). Nevertheless, experience to date is limited, with scant data on outcomes in patients with papillary thyroid carcinoma (PTC). Read More

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December 2018
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Nasal function and CPAP compliance.

Auris Nasus Larynx 2018 Dec 8. Epub 2018 Dec 8.

Department of Otorhinolaryngology, Toho University Graduate School of Medicine, Japan; Department of Otorhinolaryngology, Toho University Omori Medical Center, Japan. Electronic address:

Objective: Continuous positive airway pressure (CPAP) is the mainstay therapy for patients with obstructive sleep apnea (OSA) however compliance with CPAP is variable. Nasal ailments, such as nasal congestion are frequently mentioned as a cause for CPAP non-compliance, and potentially could be addressed prior to CPAP initiation, however, no specific criteria or recommendations for the evaluation and management of these patients exist. The aim of this retrospective study is to evaluate the effects of nasal anatomic features and disease on adherence to CPAP therapy for patients with OSA and determine the indications for pre-CPAP nasal treatment by using data obtained at clinical examination. Read More

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December 2018

Reversal of hoarseness with recognition of Ortner syndrome in a patient with severe mitral regurgitation.

J Cardiol Cases 2013 Feb 8;7(2):e48-e50. Epub 2012 Dec 8.

Department of Second Section of Cardiology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 5 Fuxing Street, Guishan Township, Taoyuan County 33305, Taiwan.

Loss of voice due to vocal cord paralysis, as in Ortner syndrome, is secondary to left recurrent laryngeal nerve palsy. Cardiovascular cause should be listed as a differential diagnosis of hoarseness and is incumbent upon the diagnostic physician to be familiar with the condition. A 56-year-old male presented to our emergency department with shortness of breath due to severe mitral regurgitation. Read More

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February 2013

EA promotes swallowing via activating swallowing-related motor neurons in the Nucleus Ambiguus.

Brain Res 2018 Dec 8. Epub 2018 Dec 8.

Guangzhou University of Chinese Medicine, No.232 Waihuan East Road, Panyu District Guangzhou, Guangdong province, 510006,China. Electronic address:

To observe the effect of electroacupuncture (EA) on swallowing and its underlying mechanism, 32 Sprague-Dawley (SD) rats were chose and the electrophysiology was used to detect the discharge of nucleus ambiguus (NA) after EA at CV23 (Lianquan), GV16 (Fengfu), and other acupoints. The swallowing-related motor neuron was identified by antidromic stimulation through recurrent laryngeal nerve. Meanwhile, the swallowing numbers were induced by Double-distilled water (DDW) and the neuron discharges were recorded before and after EA. Read More

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December 2018
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