3,806 results match your criteria Lactose Intolerance

Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities.

Hum Reprod 2022 Jun 17. Epub 2022 Jun 17.

Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.

Study Question: Do the spectrum and prevalence of comorbidities of endometriosis and irritable bowel syndrome (IBS) overlap?

Summary Answer: Despite several overlapping symptoms, the most significantly associated comorbidities of endometriosis and IBS are different and are rather related to the organ systems primarily involved in the index diagnosis.

What Is Known Already: Endometriosis and IBS both have several similar unspecific symptoms, such as recurrent abdominal pain, cramping and anxiety, and both diseases affect young women and are associated with a number of comorbidities causing a poor quality of life. However, a detailed study, revealing the full spectrum of endometriosis and IBS comorbidities in the same study population, is lacking. Read More

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Short-Term Dairy Product Elimination and Reintroduction Minimally Perturbs the Gut Microbiota in Self-Reported Lactose-Intolerant Adults.

mBio 2022 Jun 13:e0105122. Epub 2022 Jun 13.

Department of Medicine, Stanford University School of Medicinegrid.471392.a, Stanford, California, USA.

An outstanding question regarding the human gut microbiota is whether and how microbiota-directed interventions influence host phenotypic traits. Here, we employed a dietary intervention to probe this question in the context of lactose intolerance. To assess the effects of dietary dairy product elimination and (re)introduction on the microbiota and host phenotype, we studied 12 self-reported mildly lactose-intolerant adults with triweekly collection of fecal samples over a 12-week study period: 2 weeks of baseline diet, 4 weeks of dairy product elimination, and 6 weeks of gradual whole cow milk (re)introduction. Read More

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Health-Promoting Nature of IBB109 and IBB417 Strains Exhibiting Proliferation Inhibition and Stimulation of Interleukin-18 Expression in Colorectal Cancer Cells.

Front Microbiol 2022 25;13:822912. Epub 2022 May 25.

Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland.

Lactic acid bacteria (LAB) are Gram-positive bacteria which are considered for use as adjuvant therapeutics in management of various disease ailments, including obesity, irritable bowel syndrome, lactose intolerance and cancer. To investigate the possible use of strains from our collection in treatment of gastrointestinal cancer, we tested them for the ability to arrest proliferation of human colorectal adenocarcinoma cells (Caco-2). Results of the BrdU assay showed that the anti-proliferative activity of cells is strain-specific. Read More

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The stressing life of Lactobacillus delbrueckii subsp. bulgaricus in soy milk.

Food Microbiol 2022 Sep 22;106:104042. Epub 2022 Apr 22.

STLO, INRAE, Institut Agro, F-35000, Rennes, France.

Lactobacillus delbrueckii subsp. bulgaricus is a beneficial lactic acid bacterium and constitutes one of the most used, and thus consumed, dairy starters, worldwide. This homofermentative bacterium was the first lactobacillus described and is involved in the fermentation of yogurt and of diverse other fermented products, including cheeses. Read More

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September 2022

Diagnostic therapeutic care pathway for pediatric food allergies and intolerances in Italy: a joint position paper by the Italian Society for Pediatric Gastroenterology Hepatology and Nutrition (SIGENP) and the Italian Society for Pediatric Allergy and Immunology (SIAIP).

Ital J Pediatr 2022 Jun 10;48(1):87. Epub 2022 Jun 10.

Pediatric Clinic, IRCCS "S. Matteo" Foundation, University of Pavia, Pavia, Italy.

Epidemiologic data suggest an increased prevalence of pediatric food allergies and intolerances (FAIs) during the last decades. This changing scenario has led to an increase in the overall healthcare costs, due to a growing demand for diagnostic and treatment services. There is the need to establish Evidence-based practices for diagnostic and therapeutic intervention that could  be adopted in the context of public health policies for FAIs are needed. Read More

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The Association of Lactose Intolerance With Colon and Gastric Cancers: Friend or Foe?

Cureus 2022 May 3;14(5):e24713. Epub 2022 May 3.

Department of Gastroenterology and Hepatology, Augusta University Medical College of Georgia, Augusta, USA.

Background: Lactose intolerance (LI) appears usually in later ages when the lactase enzyme becomes deficient or absent in the small intestine. Conflicting results have been reported in the literature about the association of lactose intolerance with various gastrointestinal malignancies. Hence, our aim was to study the association between LI, colon cancer (CCa), and gastric cancer (GC) using a large database. Read More

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Effects of different combinations of probiotics on rheology, microstructure, and moisture distribution of soy materials-based yogurt.

J Food Sci 2022 May 31. Epub 2022 May 31.

College of Food Science and Technology, Bohai University, Jinzhou, China.

The effects of different probiotics on the texture, rheological properties, microstructure, and water distribution of yogurt fermented with soy powder, soy isolate protein powder, soy umbilical powder, and soy whey as the main raw materials were studied. The soy materials-based yogurt fermented by Danisco mixed probiotic reached the end of fermentation after 4 h, which significantly shortened the fermentation time compared with other probiotic combinations. The fermentation with Danisco mixed probiotic and Kefir mixed probiotic respectively resulted in good texture and a denser and more homogeneous microstructure, which was consistent with the sensory evaluation results. Read More

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Serum Diamine Oxidase Values, Indicating Histamine Intolerance, Influence Lactose Tolerance Breath Test Results.

Nutrients 2022 May 12;14(10). Epub 2022 May 12.

Division of Immunology and Pathophysiology, Otto Loewi Research Center, Medical University of Graz, Heinrichstrasse 31a, 8010 Graz, Austria.

Lactose intolerance (LIT) is one of the major causes of irritable bowel syndrome (IBS) spectrum complaints. Differences in inadequate lactose digestion are described as various LIT phenotypes with basically unknown pathophysiology. In LIT patients, we retrospectively assessed the effect of histamine intolerance (HIT) on expiratory hydrogen (H) during H lactose breath tests. Read More

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Lactose: Characteristics, Food and Drug-Related Applications, and Its Possible Substitutions in Meeting the Needs of People with Lactose Intolerance.

Foods 2022 May 19;11(10). Epub 2022 May 19.

AILI-Associazione Italiana Latto-Intolleranti Aps, 55100 Lucca, Italy.

The recent growing interest in lactose intolerance has resulted in the proliferation of lactose-free products by food manufacturing companies. Since updated papers about lactose and its uses are missing, the main purpose of this review is to investigate this sugar comprehensively. Firstly, its chemical and physical characteristics were studied, following its employment in the food and drug industries. Read More

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Functional Fermented Probiotics, Prebiotics, and Synbiotics from Non-Dairy Products: A Perspective from Nutraceutical.

Mol Nutr Food Res 2022 May 26:e2101059. Epub 2022 May 26.

ICAR-Central Potato Research Institute, Shimla, Himachal Pradesh, 171001, India.

The current trend of health-conscious consumers and healthy food habits prompts researchers to explore developing food products with synbiotic benefits. Synbiotic foods have gained popularity in recent years due to their functional, nutritional, physiological, and therapeutic characteristics. Lactose intolerance, dyslipidemia, and allergic milk proteins become the barriers in the development of dairy probiotics. Read More

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International Cross-Sectional Survey among Healthcare Professionals on the Management of Cow's Milk Protein Allergy and Lactose Intolerance in Infants and Children.

Pediatr Gastroenterol Hepatol Nutr 2022 May 9;25(3):263-275. Epub 2022 May 9.

Department of Pediatrics, University of the Philippines, Philippine General Hospital, Manila, Philippines.

Purpose: The present international survey among healthcare providers aimed to collect data on theoretical knowledge and clinical practices in the diagnosis and management of cow's milk protein allergy (CMPA) and lactose intolerance (LI) in infants.

Methods: A global survey was conducted in several countries with diverse health care settings. The survey consisted of multiple-choice questions in 3 main domains: (1) understanding and clinical practices around CMPA and LI; (2) case scenarios; and (3) disease-specific knowledge and potential educational needs. Read More

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[Assessment of the state of the small intestine microbiota in children on a long-term dairy-free diet].

Vopr Pitan 2022 14;91(2):15-20. Epub 2022 Mar 14.

M. Gorky Donetsk National Medical University, 283003, Donetsk, Donetsk People's Republic.

An overview of recent outcomes of studies indicates an imbalance in the diet of children. Quantitative and qualitative malnutrition of children is the basis of a number of childhood diseases. of the research was to study the prevalence of small intestine bacterial overgrowth syndrome (SIBO) in children on a long-term dairy-free diet. Read More

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Carbohydrate Maldigestion and Intolerance.

Nutrients 2022 May 4;14(9). Epub 2022 May 4.

Department of Gastroenterology, Hospital Universitary MútuaTerrassa, 08221 Terrassa, Spain.

This review summarizes dietary carbohydrate intolerance conditions and recent advances on the possible role of carbohydrate maldigestion and dietary outcomes in patients with functional bowel disease. When malabsorbed carbohydrates reach the colon, they are fermented by colonic bacteria, with the production of short-chain fatty acids and gas lowering colonic pH. The appearance of diarrhoea or symptoms of flatulence depends in part on the balance between the production and elimination of these fermentation products. Read More

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The Relationship between Fluid Milk, Water, and 100% Juice and Health Outcomes among Children and Adolescents.

Nutrients 2022 Apr 30;14(9). Epub 2022 Apr 30.

Department of Food Science and Human Nutrition, Division of Nutritional Sciences, University of Illinois Urbana Champaign, Urbana, IL 61801, USA.

Beverages can provide improved nutrient intake and hydration, but also pose concerns related to overnutrition or contamination for children and adolescents who are in a time of critical growth. This narrative review aims to understand the impact of milk, 100% juice, and water consumption on health-related outcomes in youth. The literature review conducted used PubMed, Web of Science, and CABI global. Read More

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Can Lactose Intolerance Be a Cause of Constipation? A Narrative Review.

Nutrients 2022 Apr 24;14(9). Epub 2022 Apr 24.

Department of Paediatrics, Gastroenterology, Allergology and Paediatric Nutrition, Faculty of Medicine, Medical University of Gdańsk, Nowe Ogrody 1-6, 80-803 Gdańsk, Poland.

Lactose intolerance and constipation are common in children and impact everyday life, not only for patients but also their families. Both conditions can be comorbid with other diseases or form a part of their clinical presentation, but constipation is not usually associated with lactose intolerance. The typical symptoms of lactose intolerance include abdominal pain, bloating, flatus, diarrhoea, borborygmi, and less frequently nausea and vomiting. Read More

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Gastrointestinal Conditions: Malabsorption Syndromes.

FP Essent 2022 May;516:31-37

University of Kansas School of Medicine-Wichita, 1010 North Kansas, Wichita, KS 67214-3199.

Malabsorption syndromes are a heterogenous group of conditions that can cause distressing gastrointestinal symptoms. Celiac disease is most common and is triggered by exposure to gluten. Tissue transglutaminase immunoglobulin A is the diagnostic test of choice; management is gluten avoidance. Read More

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Continuing Medical Education Questions: May 2022.

Sumant Inamdar

Am J Gastroenterol 2022 May;117(5):719

University of Arkansas for Medical Science (UAMS), Little Rock, Arkansas.

Article Title: Evolutionary medicine perspectives: Helicobacter pylori lactose intolerance, and three hypotheses for functional and inflammatory gastrointestinal and hepatobiliary disorders. Read More

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Circulatory amino acid responses to milk consumption in dairy and lactose intolerant individuals.

Eur J Clin Nutr 2022 Apr 22. Epub 2022 Apr 22.

The Riddet Institute, Palmerston North, 4442, New Zealand.

Background/objectives: Self-reported digestive intolerance to dairy foods is common. As dairy can be an important source of dietary protein, this study aimed to identify whether milk protein digestion is compromised in individuals with digestive intolerance.

Subjects/methods: Adult women (n = 40) were enroled in this double-blinded, randomised cross-over trial, with digestive symptoms characterised using a lactose challenge and self-reported digestive symptom questionnaire. Read More

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Physicochemical, Microbiological and Microstructural Characteristics of Sucrose-Free Probiotic-Frozen Yogurt during Storage.

Foods 2022 Apr 12;11(8). Epub 2022 Apr 12.

Department of Dairy Science, Faculty of Agriculture, Benha University, Moshtohor 13736, Egypt.

Frozen yogurt is known as ice cream with some properties of yogurt. Frozen yogurts are a rich source of sucrose levels between 15% and 28% of total ingredients. Consumers suffering from lactose intolerance and metabolic syndrome are looking for sugar-free products. Read More

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Gene variants of the SLC2A5 gene encoding GLUT5, the major fructose transporter, do not contribute to clinical presentation of acquired fructose malabsorption.

BMC Gastroenterol 2022 Apr 6;22(1):167. Epub 2022 Apr 6.

Department of Molecular Genetics, Medical Laboratory for Clinical Chemistry, Microbiology, Infectious Diseases and Genetics "Prof. Schenk/Dr. Ansorge and Colleagues", Schwiesaustr. 11, 39124, Magdeburg, Germany.

Background: While role of ALDOB-related gene variants for hereditary fructose intolerance is well established, contribution of gene variants for acquired fructose malabsorption (e.g. SLC2A5, GLUT5) is not well understood. Read More

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Helicobacter pylori infection and lactose intolerance increase expiratory hydrogen.

EXCLI J 2022 17;21:426-435. Epub 2022 Feb 17.

Division of Immunology and Pathophysiology, Otto Loewi Research Center, Medical University of Graz, Heinrichstrasse 31a, A-8010 Graz, Austria.

Infection with () may cause dyspepsia and/or unexplained functional nonspecific, gastrointestinal complaints of the irritable bowel syndrome (IBS) spectrum. Hitherto, in infected patients with symptoms of the IBS spectrum the occurrence of additional food intolerance/malabsorption is not evaluated. We used a retrospective analysis of charts from 548 patients who presented with gastrointestinal complaints of the irritable bowel syndrome spectrum. Read More

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February 2022

Relationships of Intestinal Lactase and the Small Intestinal Microbiome with Symptoms of Lactose Intolerance and Intake in Adults.

Dig Dis Sci 2022 Mar 23. Epub 2022 Mar 23.

Division of Gastroenterology and Hepatology, Department of Medicine, Indiana University School of Medicine, 702 Rotary Circle, Suite 225, Indianapolis, IN, 46202, USA.

Background: Approximately two-thirds of adults are genetically predisposed to decreased lactase activity after weaning, putting them at risk of lactose intolerance. However, symptoms are a poor marker of lactose maldigestion.

Aims: We assessed association between self-reported lactose intolerance and intestinal lactase, lactose intake, and the small intestinal microbiome. Read More

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Validation of a modified cow's milk-related symptom score (CoMISS) for screening of lactose intolerance in adults.

Curr Med Res Opin 2022 Jun 20;38(6):947-953. Epub 2022 Apr 20.

Department of Internal Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Introduction: Lactose intolerance (LI) is the failure to digest foods and beverages containing the lactose present in milk. LI can present by many digestive symptoms.

Objective: To validate the modified CoMiSS score for prediction of LI, that was confirmed by a stool acidity test. Read More

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Influence of on the small intestine and lactase enzyme activity.

J Parasit Dis 2022 Mar 24;46(1):243-253. Epub 2021 Aug 24.

Parasitology Department, Kasr Al-Ainy School of Medicine, Cairo University, Cairo, Egypt.

is a cosmopolitan protozoan that has been associated with several gastrointestinal disturbances involving lactose intolerance. However, the underlying pathogenic factors remain indistinct. 20 Swiss albino mice were utilized and assembled into four groups, each of five mice: group-I: received neither infection nor lactose (healthy control), group-II: received a single dose of 10,000 cysts of and lactose diets in a dose of 12. Read More

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Lactose Malabsorption and Presumed Related Disorders: A Review of Current Evidence.

Nutrients 2022 Jan 28;14(3). Epub 2022 Jan 28.

Gastroenterology Unit, Brotzu Hospital, 09121 Cagliari, Italy.

Background: Lactose malabsorption (LM) is a frequent clinical problem associated with several digestive and extra-digestive diseases. The aim of this manuscript was to clarify the real clinical impact of LM on these disorders.

Methods: A literature search for digestive and extra-digestive disorders related to LM was carried out using PubMed, Medline and Cochrane. Read More

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January 2022

A Survey to Identify the Current Management of Cow's Milk Disorders and the Role of Goat Milk-Based Formulas in the Middle East and North Africa Region.

Nutrients 2022 Mar 3;14(5). Epub 2022 Mar 3.

KidZ Health Castle, UZ Brussel, Vrije Universiteit Brussel, 1090 Brussels, Belgium.

Background: Cow's milk allergy (CMA) and cow's milk intolerance (CMI) are the major cow's milk disorders observed in infants and young children. This study investigates, for the first time, physician knowledge regarding CMA and CMI prevalence, diagnosis, and management in the Middle East and North Africa (MENA) region. In addition, we explore the role of goat milk-based formula as an alternative in infants suffering from CMI. Read More

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Functional dairy products as a source of bioactive peptides and probiotics: current trends and future prospectives.

J Food Sci Technol 2022 Apr 11;59(4):1263-1279. Epub 2021 Apr 11.

Department of Food Processing and Preservation, Hajee Mohammad Danesh Science and Technology University, Dinajpur, 5200 Bangladesh.

Milk is an incredibly healthy food world-wide. However, the 'lactase deficient' individuals cannot digest milk's carbohydrate lactose. A large part of the world population is depriving of highly beneficial milk proteins like casein, lactoalbumin, lactoglobulin, etc. Read More

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Switching from the tablet to the powder formulation of levothyroxine corrects severe hypothyroidism in a patient with lactose intolerance.

Endocr J 2022 Mar 4. Epub 2022 Mar 4.

Department of Endocrinology and Metabolism, Dokkyo Medical University, Tochigi 321-0293, Japan.

We describe a case of a 38-year-old woman who, after radioactive iodine therapy for Graves' disease, developed severe hypothyroidism despite receiving a high dose of levothyroxine (L-T4) tablet as replacement therapy. Her thyroid stimulating hormone (TSH) remained to be high despite the dose of L-T4 tablets to 400 μg/day after treatment for hypothyroidism, and the patient complained of general malaise and edema of the legs. Reduced intestinal absorption of L-T4 is the most common cause of failure to achieve the therapeutic target in hypothyroid patients receiving replacement therapy. Read More

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Effects of Koumiss on Intestinal Immune Modulation in Immunosuppressed Rats.

Front Nutr 2022 14;9:765499. Epub 2022 Feb 14.

Department of Pharmacy, Baotou Medical College, Baotou, China.

Koumiss is a traditional fermented dairy product with health and medicinal benefits. It is very popular in the Inner Mongolia Autonomous Region of China. The results of relevant studies have shown that koumiss can regulate the gastrointestinal environment, improve the absorption of nutrients, improve the body's intolerance to lactose, enhance the body's immunity, prevent scurvy and atherosclerosis, and aid in the treatment of tuberculosis. Read More

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February 2022

Evolution of Milk Consumption and Its Psychological Determinants: A Mini-Review.

Front Nutr 2022 11;9:845154. Epub 2022 Feb 11.

EngageMinds HUB-Consumer, Food & Health Engagement Research Center, Milan, Italy.

The consumption of lactose-free products and in particular lactose-free milk is increasing worldwide. Although many studies claim that this dietary trend is mainly determined by the number of lactose intolerant people that is growing, others state that most of them self-report an intolerance that has not been diagnosed by medical tests. However, many researchers reported that the consumption of lactose-free milk may put the consumers' health at risk especially when the subjects are not intolerant. Read More

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February 2022