3,643 results match your criteria Lactose Intolerance


Guidelines Suggesting Children Avoid Plant-Based Milks: A Closer Examination.

Matern Child Health J 2020 Jun 30. Epub 2020 Jun 30.

Plant Based New Zealand Health Charitable Trust, Gisborne, New Zealand.

Recent Healthy Drinks, Healthy Kids (HDHK) guidelines state children between 12 and 24 months need to be consuming 2-3 cups a day of whole fat cow's milk, and less of all other beverages except water. Guidelines explicitly state plant-based milks should be avoided (with the exception of soy milk). We agree that in the first 12 months the optimal food for childhood growth is breast milk, with formula used where needed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10995-020-02970-yDOI Listing

Nutritional management of lactose intolerance: the importance of diet and food labelling.

J Transl Med 2020 Jun 26;18(1):260. Epub 2020 Jun 26.

Dietetics and Clinical Nutrition Laboratory, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.

Worldwide, 70% of the adult population has limited expression of lactase enzyme with a wide variation among different regions and countries. Lactase deficiency may lead to lactose intolerance (LI). Depending both on the amount of lactose ingested and on the lactase activity, people who suffer from lactose malabsorption might experience numerous gastrointestinal and extra-intestinal symptoms and manifestations. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12967-020-02429-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318541PMC

The importance of nutritional factors and dietary management of Hashimoto's thyroiditis.

Ann Agric Environ Med 2020 Jun 2;27(2):184-193. Epub 2019 Oct 2.

Nencki Institute of Experimental Biology PAN, Poland.

Hashimoto (HT) is an autoimmune disease in which destruction of the thyroid occurs as a result of lymphocyte infiltration. It is caused by an increased level of titers of antibody against thyroid peroxidase (TPO) and thyroglobulin (TG). Because of that,in HT patients, changes are observed in the level and metabolism of thyroid hormones, which leads to unspecified physical and psychological symptoms. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.26444/aaem/112331DOI Listing

Lactose Intolerance: What Your Breath Can Tell You.

Diagnostics (Basel) 2020 Jun 17;10(6). Epub 2020 Jun 17.

Department of Pharmaceutical Sciences, Massachusetts College of Pharmacy and Health Sciences University, Boston, MA 02115, USA.

Lactose intolerance has seen recognized as a clinical syndrome characterized by pain, abdominal distention, flatulence, and diarrhea after the consumption of lactose. Lactose is a common disaccharide found in dairy that requires lactase-phlorizin hydrolase (LPH) to break down into glucose and galactose. A deficiency in this enzyme results in flora bacteria further along in the gastrointestinal tract (GI) tract to metabolize the excess lactose to numerous gases, including H. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/diagnostics10060412DOI Listing

Effects of Consumption of Coconut and Cow's Milk on the Metabolic Profile of Wistar Rats Fed a Hyperprotein Diet.

J Med Food 2020 Jun 16. Epub 2020 Jun 16.

Department of Medical Sciences, School of Medicine, University of Marília (UNIMAR), Marília, Brazil.

The intake of milk has decreased over the past few decades in Western populations and has been replaced by drinks of plant origin. Substitution of cow's milk by vegetable drinks occurs for some reasons, such as the presence of lactose intolerance, reduced calorie intake, prevention of obesity, vegan diets, and concern about the use of hormone therapy and its possible residues in bovine milk. For these reasons, the objective of this study was to evaluate the biochemical and anthropometric profile of animals subjected to a diet supplemented with coconut milk. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/jmf.2020.0031DOI Listing

Milk-free diet followed by breastfeeding women.

Rocz Panstw Zakl Hig 2020 ;71(2):181-189

Warsaw University of Life Sciences - SGGW, Institute of Human Nutrition Sciences. Department of Dietetics, Warsaw, Poland.

Background: Breastfeeding is the most common way of feeding infants. Human milk contains nutrients which are necessary to provide proper growth of a child. Nowadays there aren't any recommendations to follow elimination diet in order to decrease the risk of allergy or baby colic. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.32394/rpzh.2020.0118DOI Listing
January 2020

Food intolerance/malabsorption may occur in rare diseases.

Intractable Rare Dis Res 2020 May;9(2):126-129

Clinical Institute of Medical and Chemical Laboratory Diagnosis, Medical University of Graz, Auenbruggerplatz 30, Graz, Austria.

Sugars including lactose and fructose, or proteins (gluten), or biogenic amines (histamine), and combinations thereof may cause food intolerance/malabsorption. However, in usually asymptomatic patients with rare diseases, who present with functional, non-specific, non-allergic gastrointestinal (GI) complaints the etiologic factors of food intolerance/malabsorption need to be evaluated. We summarize patients with rare diseases, such as primary epiploic appendagitis, beta-thalassemias minor, Gullo syndrome and anomaly of the inferior vena cava, who presented functional, non-specific, non-allergic GI complaints. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5582/irdr.2020.01029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263995PMC

The importance of lactose intolerance in individuals with gastrointestinal symptoms.

Rev Gastroenterol Mex 2020 May 29. Epub 2020 May 29.

Departamento de Gastroenterología, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán.

Lactose intolerance is a condition with an elevated prevalence worldwide, especially in Latin American, Asian, and African countries. The aim of the present narrative review was to highlight the importance of accurately diagnosing lactose intolerance to prevent self-diagnosis that results in the unnecessary elimination of milk and dairy products from the diet and the consequent deprivation of nutrients that could be essential at certain stages of life. The pathophysiologic mechanism of deficient lactose absorption in the intestine can be primary, secondary to other enteropathies, or coexistent with other intestinal diseases with similar symptoms, such as irritable bowel syndrome, bacterial overgrowth syndrome, or celiac disease, causing confusion in relation to diagnosis and treatment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.rgmx.2020.03.002DOI Listing

Valid Assessment of Carbohydrate Intolerance and the Need for a Distinction to Carbohydrate Malabsorption. Comment on "Roles of Lactose and Fructose Malabsorption and Dietary Outcomes in Children Presenting with Chronic Abdominal Pain.", , 2019, , 3063.

Nutrients 2020 May 26;12(6). Epub 2020 May 26.

Abteilung für Gastroenterologie und Hepatologie, Universitätsklinik für Innere Medizin 3, Medical University of Vienna, 1090 Vienna, Austria.

We have read with interest the recent paper by Posovszky and Roesler et al [1] that reports, based on the doctoral thesis by Dr. Roesler [2] [.. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/nu12061546DOI Listing

Individualized target fortification of breast milk with protein, carbohydrates, and fat for preterm infants: A double-blind randomized controlled trial.

Clin Nutr 2020 May 6. Epub 2020 May 6.

Division of Neonatology, Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada; Department of Pediatrics, Paracelsus Medical School, General Hospital of Nuremberg, Nuremberg, Germany. Electronic address:

Background & Aims: In preterm infants, natural variation of breast milk composition makes it difficult to achieve recommended macronutrient intakes with standard fortification. Evidence suggests that nutritional deficiency induces poor postnatal growth. This study investigates impacts of target fortification on preterm growth and metabolism by adjusting breast milk macronutrients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clnu.2020.04.031DOI Listing

Effects of Prebiotic and Probiotic Supplementation on Lactase Deficiency and Lactose Intolerance: A Systematic Review of Controlled Trials.

Nutrients 2020 May 20;12(5). Epub 2020 May 20.

Department of Pediatrics, University Clinical Hospital of Santiago de Compostela, 15704 Santiago de Compostela, Spain.

Lactose intolerance (LI) is characterized by the presence of primarily gastrointestinal clinical signs resulting from colonic fermentation of lactose, the absorption of which is impaired due to a deficiency in the lactase enzyme. These clinical signs can be modified by several factors, including lactose dose, residual lactase expression, concurrent ingestion of other dietary components, gut-transit time, and enteric microbiome composition. In many of individuals with lactose malabsorption, clinical signs may be absent after consumption of normal amounts of milk or, in particular, dairy products (yogurt and cheese), which contain lactose partially digested by live bacteria. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/nu12051487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284493PMC

Milk allergy most burdensome in multi-food allergic children.

Pediatr Allergy Immunol 2020 May 15. Epub 2020 May 15.

Department of Pediatrics and Child Health, The University of Manitoba, Winnipeg, MB, Canada.

Background: Food allergy is a substantial health burden, which disproportionately affects children. Among children with food allergy, as many as 70% have multiple food allergies. Whereas the overall burden of food allergy on quality of life has been described, little is known about the burden of individual allergens. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/pai.13274DOI Listing

Estimating Lactase Nonpersistence Distributions in the Multi-Ethnic Canadian Demographic: A Population-Based Study.

J Can Assoc Gastroenterol 2020 Jun 28;3(3):103-110. Epub 2018 Nov 28.

Lady Davis Institute for Medical Research, Division of Gastroenterology, Sir Mortimer B. Davis Jewish General Hospital, Montréal, Québec, Canada.

Objectives: The lactase persistence/nonpersistence (LP/LNP) phenotypes follow a geographic pattern that is rooted in the gene-culture coevolution observed throughout the history of human migrations. The immense size and relatively open immigration policy have drawn migrants of diverse ethnicities to Canada. Among the multicultural demographic, two-thirds of the population are derived from the British Isles and northwestern France. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jcag/gwy068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204802PMC

The role of small intestinal bacterial overgrowth and false positive diagnosis of lactose intolerance in southwest Hungary-A retrospective observational study.

PLoS One 2020 8;15(5):e0230784. Epub 2020 May 8.

Division of Gastroenterology, First Department of Medicine, Medical School, University of Pécs, Pécs, Hungary.

Background: Lactose intolerance is a frequent gastrointestinal disease affecting 47% of the Eastern European population. Small intestinal bacterial overgrowth (SIBO) leads to carbohydrate malabsorption and therefore to false results during lactose breath and tolerance tests.

Objectives: We aimed to assess the prevalence of lactose maldigestion and intolerance in Hungary and to investigate the role of combined diagnostic method and testing for SIBO in reducing false results. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0230784PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209350PMC

Prevalence of Disaccharidase Deficiency in Adults With Unexplained Gastrointestinal Symptoms.

J Neurogastroenterol Motil 2020 Jun;26(3):384-390

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Augusta University, Augusta, GA, USA.

Background/aims: Disaccharidase assay is used for assessing carbohydrate intolerance in children, but its usefulness in adults is not known. The aim of this study is to assess the prevalence of disaccharidase deficiency in patients with unexplained gastrointestinal symptoms.

Methods: A retrospective review of adults with chronic (> 1 year) abdominal symptoms and negative imaging and endoscopy/colonoscopy and who completed bowel symptom questionnaire and duodenal biopsy for lactase, maltase, sucrase, and palatinase was performed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5056/jnm19167DOI Listing

Preparation of Low-Lactose Milk Powder by Coupling Membrane Technology.

ACS Omega 2020 Apr 8;5(15):8543-8550. Epub 2020 Apr 8.

Center for Membrane Separation and Water Science & Technology, College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, P. R. China.

Due to lactose intolerance, there is a growing need for lactose-free or low-lactose dairy products. Herein, a combination of three membrane technologies (UF, electrodialysis (ED), and nanofiltration (NF)) was used as a novel green technology to replace the enzymatic preparation of low-lactose milk powder in the traditional industry. In which, large molecules such as proteins and fats are first retained using UF, mineral salt was intercepted and re-added into milk by electrodialysis, and finally, lactose is recovered by NF. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acsomega.9b04252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178344PMC

Osmolality and molar mass of oligosaccharides in breast milks and infant formula during hydrolysis of lactose. Application of high-resolution ultrasonic spectroscopy.

Food Chem 2020 Aug 21;322:126645. Epub 2020 Mar 21.

School of Chemistry., University College Dublin, Belfield, Dublin 4, Ireland. Electronic address:

β-Galactosidase formulations can be added to infant milks prior to feeding to reduce the level of lactose and to avoid symptoms of lactose intolerance. The hydrolysis of lactose affects osmolality, which is an important property of infant milk. This paper introduces novel ultrasonic technology for precision, real-time, non-destructive monitoring of osmolality of infant milks, including breast milk, during enzymatic hydrolysis of lactose by supplemental β-galactosidases. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.foodchem.2020.126645DOI Listing

Colonic mucosal inflammatory cells in children and adolescents with lactase deficiency.

Pathol Res Pract 2020 Jun 14;216(6):152971. Epub 2020 Apr 14.

Children's Mercy Hospital, Division of Gastroenterology, Kansas City, MO, United States.

Introduction And Objectives: Many of the symptoms of patients with lactose intolerance are due to fermentation of undigested lactose in the colonic lumen, which may also lead to inflammatory cell changes in the colonic mucosa. The objective of our project was to understand the histopathological changes involving infiltration of eosinophils and mast cells in the colonic mucosa of children with lactase deficiency (LD).

Methods: In this retrospective study we studied colonic mucosa of children and adolescents with LD to determine if any pathological changes or inflammatory cell changes were present. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.prp.2020.152971DOI Listing
June 2020
1.562 Impact Factor

Molecular Routes to Specific Identification of the Lactobacillus Casei Group at the Species, Subspecies and Strain Level.

Int J Mol Sci 2020 Apr 13;21(8). Epub 2020 Apr 13.

Department of Biotechnology, Microbiology and Human Nutrition, University of Life Sciences in Lublin, 8 Skromna St., 20-704 Lublin, Poland.

The genus includes, among others, , and species that are collectively referred to as the group. Many studies have shown that strains belonging to this group may decrease lactose intolerance, the effects of inflammatory bowel disease, diarrhea, constipation, food allergies and even colon cancer. Moreover, evidences exists of positive effects of these bacteria on mucosal immunity and blood cholesterol level. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms21082694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216162PMC

Galacto-Oligosaccharide RP-G28 Improves Multiple Clinical Outcomes in Lactose-Intolerant Patients.

Nutrients 2020 Apr 10;12(4). Epub 2020 Apr 10.

Meredith Professor of Nutrition Science, Institution: Purdue University, West Lafayette, IN 47907, USA.

Lactose intolerance (LI) is a global problem affecting more than half of the world's population. An ultra-purified, high-concentration galacto-oligosaccharide, RP-G28, is being developed as a treatment for patients with LI. The efficacy and safety of RP-G28 in reducing symptoms of lactose intolerance were assessed in a blinded, randomized, placebo-controlled trial. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/nu12041058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231374PMC

Health issues and technological aspects of plant-based alternative milk.

Food Res Int 2020 May 7;131:108972. Epub 2020 Jan 7.

Escola de Química, UFRJ. Av. Athos da Silveira Ramos, 149, bloco E - Cidade Universitária, Rio de Janeiro, RJ 21044-020, Brazil. Electronic address:

A growing number of consumers opt for plant-based milk substitutes for medical reasons, like cow's milk protein allergy (CMPA), lactose intolerance (LI), or as a lifestyle choice. Plant-based milk substitutes, or plant extracts, are water-soluble extracts of legumes, oilseeds, cereals or pseudocereals that resemble bovine milk in appearance. It is produced by reducing the size of the raw material, extracted in water and subsequently homogenized, being an alternative to cow's milk. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.foodres.2019.108972DOI Listing

Lactose intolerance.

Authors:
Andrea S Wiley

Evol Med Public Health 2020 17;2020(1):47-48. Epub 2020 Feb 17.

Department of Anthropology, Indiana University, 130 Student Building, Bloomington, IN 47405, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/emph/eoaa006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081935PMC
February 2020

John Goodsir: discovering and diagnosing Darwin's dyspepsia.

Scott Med J 2020 May 24;65(2):40-45. Epub 2020 Mar 24.

Director of Heritage, Surgeons' Hall Museums, Edinburgh, UK.

In 1842, when John Goodsir was Conservator to the Museum of the RCSEd, he saw a 19-year-old male patient who vomited a large volume of acidic, fermented-smelling, watery fluid every morning. Under his microscope, Goodsir found the vomitus to be populated with a micro-organism he named , which he considered to be causative. In so-doing, Goodsir became one of the first people to link a specific micro-organism with a disease. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0036933020912329DOI Listing

Cognition and hospitalizations are linked with salivary and faecal microbiota in cirrhosis cohorts from the USA and Mexico.

Liver Int 2020 Jun 1;40(6):1395-1407. Epub 2020 Apr 1.

George Mason University, Manassas, VA, USA.

Background & Aims: Gut microbiota are affected by diet and ethnicity, which impacts cognition and hospitalizations in cirrhosis.

Aim: Study interactions of diet with microbiota and impact on hospitalizations and cognition in American and Mexican cohorts.

Methods: Controls and age-balanced patients with compensated/decompensated cirrhosis were included and followed for 90-day hospitalizations. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/liv.14437DOI Listing

Spontaneously fermented curly kale juice: Microbiological quality, nutritional composition, antioxidant, and antimicrobial properties.

J Food Sci 2020 Apr 6;85(4):1248-1255. Epub 2020 Mar 6.

Dept. of Natural Science and Quality Assurance, Inst. of Quality Science, Poznan Univ. of Economics and Business, Al. Niepodległości 10, 61-875, Poznań, Poland.

Nondairy fermented products, such as fruit and vegetable juices, are gaining popularity among consumers worldwide for health-related and economic reasons. The purpose of this study was to determine the changes in microbiological quality; antimicrobial and antioxidant activity; and phenolic, vitamin C, minerals, and cadmium content occurring during spontaneous fermentation of curly kale juice. The fermentation process contributed to a significant growth of lactic acid bacteria, enterococci, and yeasts, while no pathogens of Escherichia coli and Salmonella spp. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/1750-3841.15080DOI Listing

Effect of Innovative Food Processing Technologies on the Physicochemical and Nutritional Properties and Quality of Non-Dairy Plant-Based Beverages.

Foods 2020 Mar 4;9(3). Epub 2020 Mar 4.

Centro Tecnológico de la Carne de Galicia, rúa Galicia n° 4, Parque Tecnológico de Galicia, San Cibrao das Viñas, 32900 Ourense, Spain.

Increase in allergenicity towards cow's milk, lactose intolerance, the prevalence of hypercholesterolemia, and flexitarian choice of food consumption have increased the market for cow's milk alternatives. Non-dairy plant-based beverages are useful alternatives because of the presence of bioactive components with health-promoting properties, which attract health-conscious consumers. However, the reduced nutritional value and sensory acceptability of the plant-based beverages (such as flavor, taste, and solubility) compared to cow's milk pose a big threat to its place in the market. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/foods9030288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142651PMC

Impact of gastrointestinal physiology on drug absorption in special populations--An UNGAP review.

Eur J Pharm Sci 2020 Apr 25;147:105280. Epub 2020 Feb 25.

Department of Pharmacy, University of Copenhagen, Denmark. Electronic address:

The release and absorption profile of an oral medication is influenced by the physicochemical properties of the drug and its formulation, as well as by the anatomy and physiology of the gastrointestinal (GI) tract. During drug development the bioavailability of a new drug is typically assessed in early clinical studies in a healthy adult population. However, many disease conditions are associated with an alteration of the anatomy and/or physiology of the GI tract. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejps.2020.105280DOI Listing
April 2020
3.350 Impact Factor

[Allergy to cow's milk protein, or lactose intolerance: a cross-sectional study in university students].

Rev Alerg Mex 2019 Oct-Dec;66(4):394-402

Universidad Autónoma del Estado de México, Centro de Investigación en Ciencias Médicas, Estado de México, México.

Background: Factors like ethnic origin and geographical area affect the frequency of cow's milk protein allergy (CMPA) and lactose intolerance (LI). Epidemiological information about the non-pediatric population is still missing.

Objective: To determine the prevalence of CMPA and LI in university students. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.29262/ram.v66i4.640DOI Listing
February 2020

Is There a Correlation Between Irritable Bowel Syndrome and Lactose Intolerance?

Cureus 2020 Jan 20;12(1):e6710. Epub 2020 Jan 20.

Internal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.

Irritable bowel syndrome (IBS) is a poorly understood gastrointestinal disorder that affects a significant percentage of the population and has a strong negative effect on the quality of life. The lack of known pathophysiologic mechanisms has made finding effective treatment strategies difficult. One of the common recommendations by clinicians is a trial of a lactose-free diet. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7759/cureus.6710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032600PMC
January 2020

New insights into the molecular basis of lactase non-persistence/persistence: a brief review.

Drug Discov Ther 2020 Mar 26;14(1):1-7. Epub 2020 Feb 26.

Department of Biotechnology, Baba Ghulam Shah Badshah University, Rajouri, J&K, India.

Lactose, a disaccharide and main carbohydrate in milk, requires hydrolysis in the intestinal tract to release its monosaccharides galactose and glucose for use as energy source by enterocytes. This hydrolysis is catalyzed by the enzyme lactase, a β-galactosidase located in the brush border membrane of small intestinal enterocytes. In most mammals, lactase activity declines after the weaning, a condition known as lactase non-persistence (LNP). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5582/ddt.2019.01079DOI Listing

Use of Thyroid Hormones in Hypothyroid and Euthyroid Patients; the 2019 Italian Survey.

Eur Thyroid J 2020 Jan 4;9(1):25-31. Epub 2019 Sep 4.

Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark.

Background: The incidence and prevalence of hypothyroidism are increasing and the threshold for the treatment of hypothyroid as well as individuals without evident thyroid disease with thyroid hormone is declining.

Objective: To investigate endocrinologists' use of thyroid hormones in hypothyroid and euthyroid patients in Italy, a country where different formulations of levothyroxine (LT4; tablet, liquid solution and soft-gel capsule) are available on the market.

Methods: Members of the Associazione Medici Endocrinologi (Italian Association of Clinical Endocrinologists) were invited to participate in a web-based survey investigating the topic. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000502057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024857PMC
January 2020

Recyclable thermophilic hybrid protein-inorganic nanoflowers for the hydrolysis of milk lactose.

Int J Biol Macromol 2020 May 12;151:602-608. Epub 2020 Feb 12.

Instituto de Agroquímica y Tecnología de Alimentos, CSIC, Valencia, Spain. Electronic address:

Thermostable β-galactosidase (TmLac) has been immobilized as hybrid inorganic-protein nanoflowers using salts of Cu, Mn, Zn, Co and Ca as the inorganic component. The incorporation efficiency of enzyme into the nanoflowers was higher than 95% for a protein concentration of 0.05 mg/mL. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijbiomac.2020.02.115DOI Listing

"Symptoms associated with environmental factors" (SAEF) - Towards a paradigm shift regarding "idiopathic environmental intolerance" and related phenomena.

J Psychosom Res 2020 Feb 5;131:109955. Epub 2020 Feb 5.

Health Psychology, Faculty of Psychology and Educational Sciences, University of Leuven, BE-3000, Belgium. Electronic address:

Health conditions characterized by symptoms associated with chemical, physical and biological environmental factors unrelated to objectifiable pathophysiological mechanisms are often labelled by the general term "idiopathic environmental intolerances". More specific, exposure-related terms are also used, e.g. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpsychores.2020.109955DOI Listing
February 2020

Milk and Health.

N Engl J Med 2020 Feb;382(7):644-654

From the Departments of Nutrition (W.C.W., D.S.L.) and Epidemiology (W.C.W.), Harvard T.H. Chan School of Public Health; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School (W.C.W.); the Department of Pediatrics, Harvard Medical School (D.S.L.); and the New Balance Foundation Obesity Prevention Center, Boston Children's Hospital (D.S.L.) - all in Boston.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMra1903547DOI Listing
February 2020

Human Health Effects of Lactose Consumption as a Food and Drug Ingredient.

Curr Pharm Des 2020 ;26(16):1778-1789

Area of Pharmaceutics and Food Technology, Faculty of Pharmacy, Complutense University of Madrid, 28040 Madrid, Spain.

Lactose is a reducing sugar consisting of galactose and glucose, linked by a β (1→4) glycosidic bond, considered as an antioxidant due to its α-hydroxycarbonyl group. Lactose is widely ingested through the milk and other unfermented dairy products and is considered to be one of the primary foods. On the other hand, lactose is also considered as one of the most widely used excipients for the development of pharmaceutical formulations. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1381612826666200212114843DOI Listing
January 2020

Lactose, Maltose, and Sucrose in Health and Disease.

Mol Nutr Food Res 2020 Apr 6;64(8):e1901082. Epub 2020 Apr 6.

Glycologic Limited, Glasgow, G4 0BA, UK.

Scope: This review represents a focus on the structure and properties of the common nutritional disaccharides (lactose, maltose, and sucrose) in health and disease. The aim is to provide a comprehensive reference source related to the role of disaccharides in human nutrition.

Methods And Results: Key reference sources are searched, including Web of Science, PubMed, Science Direct, and Wiley Online, and key reference works are selected to support the factual basis of the text where interpretations and relevance of the works are discussed in the review. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mnfr.201901082DOI Listing

Therapeutic Enteral Formulas in Children.

Indian Pediatr 2020 Apr 5;57(4):343-348. Epub 2020 Feb 5.

Srikanth KP(SKP). Manipal Hospitals, Bangalore, India.

Purpose: A variety of enteral formulas for various diseases have become available in India in the last few years. Awareness among pediatricians about the availability and indications for these therapeutic formulas is low.

Methods: A literature search was conducted in PUBMED and relevant data collected from all English language publications available. Read More

View Article

Download full-text PDF

Source
April 2020
1.014 Impact Factor

Consumption of Lactose, Other FODMAPs and Diarrhoea during Adjuvant 5-Fluorouracil Chemotherapy for Colorectal Cancer.

Nutrients 2020 Feb 4;12(2). Epub 2020 Feb 4.

Department of Oncology, Helsinki University Hospital and University of Helsinki, P.O. Box 180, FI-00029 HUS, Finland.

Chemotherapy-induced mucosal injury of the small intestine may interfere with the enzymes and transporters responsible for the hydrolysis and absorption of dietary carbohydrates causing diarrhoea, abdominal discomfort and pain. The aim of this study was to investigate the association between the consumption of foods rich in FODMAPs (fermentable oligo-, di- and monosaccharides and polyols) and gastrointestinal symptoms in patients receiving adjuvant therapy for colorectal cancer. The patients ( = 52) filled in a 4-day food diary at baseline and during therapy and kept a symptom diary. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/nu12020407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071323PMC
February 2020

Laktose- und Glutenintoleranz : viel Lärm um nichts ?

Rev Med Suisse 2020 Jan;16(679):235-236

Nutrition et diététique, Av. Mercier-de-Molin 2, 3960 Sierre.

View Article

Download full-text PDF

Source
January 2020

Carboxymethylpachymaran-zein coated plant microcapsules-based β-galactosidase encapsulation system for long-term effective delivery.

Food Res Int 2020 Feb 2;128:108867. Epub 2019 Dec 2.

College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China; Key Laboratory of Environment Correlative Dietology (Huazhong Agricultural University), Ministry of Education, China. Electronic address:

Oral delivery of β-galactosidase (β-Gal) for alleviating lactose intolerance is a challenge due to its degradation in the harsh gastrointestinal tract (GIT). In this study, sunflower sporopollenin exine capsules (SECs)-based systems were fabricated to serve as protective microcapsules in order to improve the stability as well as to impact the pH-responsive release of β-Gal in GIT. The SECs extraction and loading process were optimized with the maximum residual activity of 82. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.foodres.2019.108867DOI Listing
February 2020
2.818 Impact Factor

Lactose induced redox-dependent senescence and activated Nrf2 pathway.

Int J Clin Exp Pathol 2019 1;12(6):2034-2045. Epub 2019 Jun 1.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology Shanghai, China.

Lactose is a disaccharide found in milk and thus a part of our daily food intake. Upon ingestion, it is hydrolyzed to glucose and galactose by the enzyme lactase and absorbed in the small intestine. People who suffer from lactose intolerance are unable to completely digest it due to deficiency of lactase, leading to intestinal problems such as diarrhoea, and bloating. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949649PMC

Roles of Lactose and Fructose Malabsorption and Dietary Outcomes in Children Presenting with Chronic Abdominal Pain.

Nutrients 2019 Dec 16;11(12). Epub 2019 Dec 16.

University of Potsdam, Department Psychology, Counseling Psychology, Karl-Liebknecht-Str. 24-25, 14476 Potsdam, Germany.

Intolerance to lactose or fructose is frequently diagnosed in children with chronic abdominal pain (CAP). However, the causal relationship remains a matter of discussion. A cohort of 253 patients, aged 7-12 years, presenting with unexplained CAP received standardized diagnostics. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/nu11123063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950325PMC
December 2019
3.148 Impact Factor

The cryo-EM Structure of β-Galactosidase: Quaternary Structure Guides Protein Engineering.

ACS Chem Biol 2020 01 24;15(1):179-188. Epub 2019 Dec 24.

Spanish National Cancer Research Centre (CNIO) , Melchor Fernández Almagro 3 , 28029 , Madrid , Spain.

Lactose intolerance is a common digestive disorder that affects a large proportion of the adult human population. The severity of the symptoms is highly variable, depending on the susceptibility to the sugar and the amount digested. For that reason, enzymes that can be used for the production of lactose-free milk and milk derivatives have acquired singular biotechnological importance. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acschembio.9b00752DOI Listing
January 2020

Lactose Malabsorption and Lactose Intolerance in Children with Inflammatory Bowel Diseases.

Gastroenterol Res Pract 2019 1;2019:2507242. Epub 2019 Dec 1.

Department of Pediatrics, Medical University of Silesia, Katowice, Poland.

Background: Insufficient vitamin D and calcium intake associated with the restricted intake of milk and dairy products can lead to poor health outcomes like malnutrition and abnormal bone mineralization. The aim of the study was to estimate the prevalence of primary and secondary lactose intolerance in children with IBD.

Methods: The study included 107 patients (mean age 14. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2019/2507242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913261PMC
December 2019

Prospective Study of Lactose Intolerance as a Potential Cause of Gas Bloat Syndrome in Patients Treated Surgically for Gastroesophageal Reflux.

Surg Innov 2020 Apr 19;27(2):160-164. Epub 2019 Dec 19.

Hospital de Antequera, Málaga, Spain.

The high incidence of lactose intolerance leads us to consider that many of our patients could suffer from this alteration. Therefore, as its main sign (even when asymptomatic) is increased intestinal gas, patients recovering from a Nissen fundoplication have a significant probability of suffering from gas bloat syndrome. . Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1553350619891351DOI Listing

and Fructose Malabsorption: A Frequent Association.

Nutrients 2019 Dec 5;11(12). Epub 2019 Dec 5.

Joint Research Unit on Endocrinology, Nutrition and Clinical Dietetics, University of Valencia-Health Research Institute La Fe, 46026 Valencia, Spain.

Nowadays, scientific studies are emerging on the possible etiological role of intestinal parasites in functional digestive disorders. Our study was carried out with healthy individuals (control group; = 82) and symptomatic patients with lactose or fructose malabsorption, including positive (malabsorbers; = 213) and negative (absorbers; = 56) breath test, being analyzed for the presence of intestinal parasites. A high parasitic prevalence was observed in malabsorbers (41. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/nu11122973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950212PMC
December 2019

Adult lactose intolerance, calcium intake, bone metabolism and bone density in German-Turkish immigrants.

J Bone Miner Metab 2020 May 4;38(3):378-384. Epub 2019 Dec 4.

Department of Rheumatology, Immunology, Osteology and Physical Medicine, Kerckhoff Medical Campus of the Justus-Liebig University Gießen, Benekestr. 2-8, 61231, Bad Nauheim, Germany.

Introduction: Adult lactose intolerance (ALI) significantly alters calcium intake and absorption, and thus may promote osteoporosis. ALI is a recessive condition with a geographical north-south gradient characterised by decreased levels of intestinal lactase. PCR-based genotyping of lactase (LCT) gene polymorphisms is a safe and easy way to diagnose ALI and may complement diagnostic procedures to identify individuals at risk for reduced calcium intake and subsequently osteoporosis due to lactose malabsorption. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00774-019-01070-4DOI Listing

Comparison of the impact of bovine milk β-casein variants on digestive comfort in females self-reporting dairy intolerance: a randomized controlled trial.

Am J Clin Nutr 2020 01;111(1):149-160

The Liggins Institute, The University of Auckland, Auckland, New Zealand.

Background: Lactose malabsorption (LM) is a major cause of digestive discomfort from dairy products. Recently, a role for bovine β-casein A1 has been proposed.

Objectives: We examined whether there are distinct symptoms of digestive discomfort due to either lactose or differing bovine β-casein types. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ajcn/nqz279DOI Listing
January 2020

The Importance of Lactose in the Human Diet: Outcomes of a Mexican Consensus Meeting.

Nutrients 2019 Nov 12;11(11). Epub 2019 Nov 12.

FrieslandCampina, 3818 LEAmersfoort, The Netherlands.

Lactose is a unique component of breast milk, many infant formulas and dairy products, and is widely used in pharmaceutical products. In spite of that, its role in human nutrition or lactose intolerance is generally not well-understood. For that reason, a 2-day-long lactose consensus meeting with health care professionals was organized in Mexico to come to a set of statements for which consensus could be gathered. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/nu11112737DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893676PMC
November 2019

Lactose intolerance.

JAAPA 2019 11;32(11):49-50

Victoria Sainsbury Louwagie practices in the Mayo Clinic's Department of Gastroenterology and Hepatology in Mankato, Minn., and is an instructor in medicine at the Mayo Clinic College of Medicine in Rochester, Minn. The author has disclosed no potential conflicts of interest, financial or otherwise.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/01.JAA.0000586344.04372.e6DOI Listing
November 2019
1 Read